Mus musculus

0 known processes

Hils1

histone H1-like protein in spermatids 1

(Aliases: TISP64)

Hils1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amino acid metabolic processGO:000652150.409
wnt signaling pathwayGO:00160551880.209
cellular amino acid metabolic processGO:00065201030.199
amine metabolic processGO:0009308450.198
cellular chemical homeostasisGO:00550822150.186
cellular amine metabolic processGO:0044106440.176
cellular ketone metabolic processGO:0042180840.175
cellular homeostasisGO:00197252400.167
regulation of cellular ketone metabolic processGO:0010565660.167
positive regulation of cytokine secretionGO:0050715410.155
diterpenoid metabolic processGO:0016101240.152
somatotropin secreting cell differentiationGO:006012640.131
striated muscle tissue developmentGO:00147062930.112
regulation of secretion by cellGO:19035302490.109
defense response to bacteriumGO:00427421190.098
regulation of vitamin metabolic processGO:003065630.089
metal ion homeostasisGO:00550651890.088
cellular lipid metabolic processGO:00442553230.088
leukocyte differentiationGO:00025213420.084
cellular calcium ion homeostasisGO:00068741190.077
nitrogen compound transportGO:00717052710.075
multicellular organism growthGO:00352641610.075
cation homeostasisGO:00550802120.074
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.071
morphogenesis of a branching epitheliumGO:00611381930.071
nucleotide metabolic processGO:00091173320.068
hormone metabolic processGO:0042445860.067
multicellular organismal signalingGO:0035637910.066
hypophysis morphogenesisGO:004885030.065
regulation of purine nucleotide metabolic processGO:19005421690.064
skin developmentGO:00435882200.062
muscle system processGO:00030121410.061
peptidyl amino acid modificationGO:00181933360.061
positive regulation of cellular amino acid metabolic processGO:004576430.059
regulation of wnt signaling pathwayGO:00301111230.059
g protein coupled receptor signaling pathwayGO:00071862430.059
divalent inorganic cation homeostasisGO:00725071380.058
male gamete generationGO:00482322850.057
epithelial cell proliferationGO:00506731740.056
regulation of membrane potentialGO:00423911920.056
placenta developmentGO:00018901400.054
male gonad developmentGO:0008584880.054
positive regulation of cellular amine metabolic processGO:003324050.053
fertilizationGO:00095661270.053
ensheathment of neuronsGO:0007272760.052
gland developmentGO:00487323300.052
binding of sperm to zona pellucidaGO:0007339340.052
mesenchyme developmentGO:00604851520.051
purine nucleotide metabolic processGO:00061633020.050
muscle tissue developmentGO:00605373080.049
epithelial cell maturation involved in prostate gland developmentGO:006074340.049
positive regulation of protein modification processGO:00314012990.049
anatomical structure homeostasisGO:00602491450.048
regulation of cellular amine metabolic processGO:0033238200.047
ribonucleotide metabolic processGO:00092592910.047
ribonucleoside triphosphate catabolic processGO:00092031990.046
germ cell developmentGO:00072811850.046
male sex differentiationGO:00466611090.046
actin cytoskeleton organizationGO:00300362200.046
cellular metal ion homeostasisGO:00068751510.046
lipid biosynthetic processGO:00086101790.046
positive regulation of purine nucleotide metabolic processGO:19005441140.045
regulation of nucleotide metabolic processGO:00061401690.044
positive regulation of secretionGO:00510471300.044
ribose phosphate metabolic processGO:00196932910.044
sensory perceptionGO:00076002450.044
intrinsic apoptotic signaling pathwayGO:00971931320.043
regulation of kinase activityGO:00435492490.043
cellular divalent inorganic cation homeostasisGO:00725031270.043
regulation of secretionGO:00510462740.042
positive regulation of apoptotic processGO:00430652170.042
neuronal action potentialGO:0019228540.042
cytokine productionGO:00018163190.042
epithelial cell developmentGO:00020641590.042
labyrinthine layer developmentGO:0060711490.042
calcium ion homeostasisGO:00550741270.041
positive regulation of protein phosphorylationGO:00019342420.040
cellular ion homeostasisGO:00068731650.040
diencephalon developmentGO:0021536630.039
cardiac muscle tissue developmentGO:00487381300.039
regulation of transferase activityGO:00513382630.039
ossificationGO:00015032160.038
purine ribonucleotide biosynthetic processGO:0009152590.038
nucleobase containing small molecule metabolic processGO:00550863520.038
sperm motilityGO:0030317470.037
positive regulation of nucleotide metabolic processGO:00459811140.036
multi multicellular organism processGO:00447061090.036
hair cycleGO:0042633900.035
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.035
cytoplasmic transportGO:00164822340.035
macromolecule catabolic processGO:00090572810.034
nucleoside phosphate metabolic processGO:00067533380.034
organonitrogen compound biosynthetic processGO:19015661920.034
cellular response to acid chemicalGO:0071229680.034
nucleoside phosphate biosynthetic processGO:1901293790.033
regulation of cellular response to stressGO:00801351590.033
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.033
apoptotic signaling pathwayGO:00971903060.032
blastocyst developmentGO:0001824800.032
testosterone biosynthetic processGO:006137020.032
small gtpase mediated signal transductionGO:0007264970.032
phenol containing compound metabolic processGO:0018958600.032
regulation of reproductive processGO:2000241660.031
ribose phosphate biosynthetic processGO:0046390590.031
cell adhesionGO:00071553290.031
purkinje myocyte differentiationGO:000316810.031
endodermal cell fate specificationGO:000171440.031
sperm egg recognitionGO:0035036370.031
protein localization to organelleGO:00333651850.031
protein maturationGO:00516041760.030
action potentialGO:0001508780.029
negative regulation of phosphorylationGO:00423261660.029
response to extracellular stimulusGO:00099911270.029
regulation of organ morphogenesisGO:20000271440.029
asymmetric neuroblast divisionGO:005505910.029
regulation of isoprenoid metabolic processGO:001974710.029
endocytosisGO:00068971680.029
positive regulation of secretion by cellGO:19035321140.029
organic cyclic compound catabolic processGO:19013612950.029
transmission of nerve impulseGO:0019226760.028
stem cell differentiationGO:00488632680.028
circadian sleep wake cycle non rem sleepGO:004274820.028
myeloid leukocyte differentiationGO:00025731190.027
response to nutrient levelsGO:00316671090.027
rho protein signal transductionGO:0007266320.027
negative regulation of secretionGO:0051048610.027
canonical wnt signaling pathwayGO:00600701300.027
dna metabolic processGO:00062593030.027
regulation of epithelial cell proliferationGO:00506781410.027
positive regulation of growthGO:00459271040.027
thyroid stimulating hormone secreting cell differentiationGO:006012940.027
heart morphogenesisGO:00030071780.026
defense response to other organismGO:00985421970.026
cyclic nucleotide biosynthetic processGO:0009190440.026
developmental maturationGO:00217001930.026
visual perceptionGO:0007601520.026
activation of adenylate cyclase activityGO:000719040.026
response to radiationGO:00093141650.026
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.026
regulation of hormone levelsGO:00108172110.026
paramesonephric duct developmentGO:006120530.026
regulation of cell migrationGO:00303342190.025
regulation of ossificationGO:00302781120.025
oogenesisGO:0048477560.025
regulation of hydrolase activityGO:00513362460.025
purine containing compound metabolic processGO:00725213110.025
mammary gland duct morphogenesisGO:0060603380.025
retinoid metabolic processGO:0001523240.025
muscle cell differentiationGO:00426922610.025
cellular response to hormone stimulusGO:00328701500.025
myelinationGO:0042552740.025
response to organonitrogen compoundGO:00102432460.025
molting cycleGO:0042303900.025
regulation of cell adhesionGO:00301551540.025
subpallium neuron fate commitmentGO:006016320.024
intracellular protein transportGO:00068862040.024
camera type eye developmentGO:00430102660.024
regulation of metal ion transportGO:00109591060.024
female gamete generationGO:0007292740.024
cellular response to transforming growth factor beta stimulusGO:0071560880.024
striated muscle cell developmentGO:00550021250.024
negative regulation of molecular functionGO:00440922580.024
negative regulation of protein metabolic processGO:00512482820.024
positive regulation of protein transportGO:0051222930.024
cell recognitionGO:0008037830.024
cell maturationGO:00484691270.024
appendage developmentGO:00487361660.024
axon ensheathmentGO:0008366760.024
muscle cell developmentGO:00550011330.023
regulation of cell projection organizationGO:00313442060.023
innate immune response in mucosaGO:000222730.023
development of primary sexual characteristicsGO:00451371430.023
multicellular organismal homeostasisGO:00488711640.023
purine containing compound biosynthetic processGO:0072522700.023
development of primary male sexual characteristicsGO:0046546880.023
regulation of mapk cascadeGO:00434082480.022
regulation of peptide secretionGO:0002791770.022
regulation of peptide transportGO:0090087910.022
skeletal system developmentGO:00015013560.022
positive regulation of cyclic nucleotide biosynthetic processGO:0030804240.022
single fertilizationGO:0007338820.022
wound healingGO:00420601570.022
ear morphogenesisGO:00424711180.022
regulation of protein localizationGO:00328802310.022
inflammatory responseGO:00069542440.022
regulation of apoptotic signaling pathwayGO:20012331970.022
carbohydrate derivative biosynthetic processGO:19011371830.022
ras protein signal transductionGO:0007265770.021
inner medullary collecting duct developmentGO:007206120.021
negative regulation of cellular protein metabolic processGO:00322692470.021
purine nucleoside catabolic processGO:00061522050.021
cell cell recognitionGO:0009988440.021
cell divisionGO:00513011200.021
nucleoside triphosphate catabolic processGO:00091432050.021
stem cell developmentGO:00488642190.021
heterocycle catabolic processGO:00467002800.021
visual behaviorGO:0007632450.020
response to acid chemicalGO:00011011110.020
rhythmic processGO:00485111740.020
regulation of lymphocyte activationGO:00512492400.020
spermatid developmentGO:00072861080.020
protein catabolic processGO:00301632210.020
regulation of canonical wnt signaling pathwayGO:0060828820.020
regulation of circadian sleep wake cycle non rem sleepGO:004518810.020
positive regulation of cell projection organizationGO:0031346950.020
bone mineralizationGO:0030282540.020
muscle tissue morphogenesisGO:0060415530.020
neuron migrationGO:00017641220.020
positive regulation of programmed cell deathGO:00430682180.020
endocrine system developmentGO:0035270980.019
limbic system developmentGO:0021761720.019
epithelial tube morphogenesisGO:00605623030.019
glycosyl compound metabolic processGO:19016572460.019
regulation of cyclic nucleotide metabolic processGO:0030799400.019
regulation of response to woundingGO:19030341890.019
purine nucleoside metabolic processGO:00422782410.019
heart trabecula morphogenesisGO:0061384260.019
biomineral tissue developmentGO:0031214640.019
cell substrate adhesionGO:00315891300.019
limb developmentGO:00601731660.019
spermatogenesisGO:00072832840.019
cytokine metabolic processGO:0042107710.018
regulation of cytokine productionGO:00018172660.018
corpora quadrigemina developmentGO:006137820.018
ribonucleotide biosynthetic processGO:0009260590.018
embryonic placenta developmentGO:0001892980.018
blood circulationGO:00080151950.018
response to organic cyclic compoundGO:00140701980.018
regulation of cell cycle processGO:00105641600.018
morphogenesis of a branching structureGO:00017632030.018
organic hydroxy compound metabolic processGO:19016152030.018
nucleocytoplasmic transportGO:00069131390.018
regulation of cell activationGO:00508652890.017
neurotransmitter transportGO:0006836760.017
positive regulation of mapk cascadeGO:00434101700.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
response to light stimulusGO:00094161350.017
pituitary gland developmentGO:0021983380.017
regulation of heart contractionGO:0008016770.017
cellular response to lipidGO:00713961450.017
spermatid differentiationGO:00485151150.017
cytokine biosynthetic processGO:0042089680.017
ribonucleotide catabolic processGO:00092612080.017
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.017
cytosolic calcium ion homeostasisGO:0051480700.017
tissue remodelingGO:00487711020.017
regulation of ion transportGO:00432692150.017
carboxylic acid transportGO:00469421000.017
embryonic limb morphogenesisGO:00303261260.017
aromatic compound catabolic processGO:00194392860.017
peptide secretionGO:00027901140.017
nucleoside catabolic processGO:00091642060.017
leukocyte proliferationGO:00706611720.017
negative regulation of cellular component organizationGO:00511291940.016
brain morphogenesisGO:0048854320.016
cellular response to inorganic substanceGO:0071241370.016
organelle localizationGO:00516401790.016
membrane organizationGO:00610242450.016
ear developmentGO:00435832000.016
purine ribonucleoside catabolic processGO:00461302050.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
central nervous system vasculogenesisGO:002200930.016
fibroblast growth factor productionGO:009026940.016
adenohypophysis developmentGO:0021984140.016
regulation of cyclic nucleotide biosynthetic processGO:0030802310.016
purine nucleotide catabolic processGO:00061952110.016
organic acid biosynthetic processGO:0016053860.016
locomotory behaviorGO:00076261950.016
peptidyl serine modificationGO:0018209830.016
positive regulation of cytokine productionGO:00018191740.016
cellular response to oxidative stressGO:0034599760.016
regulation of body fluid levelsGO:00508781620.016
response to inorganic substanceGO:0010035960.016
forebrain cell migrationGO:0021885580.015
positive regulation of hydrolase activityGO:00513451480.015
response to coldGO:0009409190.015
organelle fissionGO:00482851700.015
regulation of peptidyl tyrosine phosphorylationGO:0050730930.015
regulation of multi organism processGO:00439001110.015
mesoderm developmentGO:00074981000.015
regulation of protein processingGO:0070613960.015
gastrin induced gastric acid secretionGO:000169810.015
embryonic organ morphogenesisGO:00485622760.015
oviduct developmentGO:006006630.015
lung inductionGO:006049230.015
positive regulation of cell deathGO:00109422240.015
mesoderm morphogenesisGO:0048332640.015
nucleoside metabolic processGO:00091162460.015
negative regulation of growthGO:0045926990.015
negative regulation of protein maturationGO:1903318790.015
purkinje myocyte developmentGO:000316510.014
adaptive immune responseGO:00022501550.014
positive regulation of camp biosynthetic processGO:0030819190.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
organ growthGO:00352651170.014
cell junction organizationGO:0034330770.014
negative regulation of cell migrationGO:0030336590.014
cardiocyte differentiationGO:0035051870.014
negative regulation of canonical wnt signaling pathwayGO:0090090510.014
bone remodelingGO:0046849530.014
positive regulation of kinase activityGO:00336741550.014
nuclear transportGO:00511691390.014
cyclic nucleotide metabolic processGO:0009187590.014
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathwayGO:005148240.014
cytokine secretionGO:0050663720.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
muscle contractionGO:00069361010.014
spinal cord oligodendrocyte cell differentiationGO:002152930.014
glial cell developmentGO:0021782540.014
homeostasis of number of cellsGO:00488722100.014
negative regulation of wnt signaling pathwayGO:0030178730.014
regulation of cell motilityGO:20001452360.014
glycosyl compound catabolic processGO:19016582060.014
establishment of organelle localizationGO:00516561220.014
negative regulation of cell proliferationGO:00082852960.014
regulation of nucleotide biosynthetic processGO:0030808340.014
cell type specific apoptotic processGO:00972852680.014
telencephalon developmentGO:00215371860.014
regulation of establishment of protein localizationGO:00702011810.014
regulation of peptidase activityGO:0052547960.014
cartilage developmentGO:00512161400.014
camp biosynthetic processGO:0006171310.014
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.014
chromosome segregationGO:0007059480.014
somatostatin signaling pathwayGO:003817020.013
developmental growth involved in morphogenesisGO:00605601380.013
renal inner medulla developmentGO:007205330.013
endomembrane system organizationGO:00102561470.013
type b pancreatic cell fate commitmentGO:000332710.013
regulation of endopeptidase activityGO:0052548890.013
regulation of erk1 and erk2 cascadeGO:0070372710.013
skin morphogenesisGO:0043589380.013
tissue homeostasisGO:00018941150.013
negative regulation of cell developmentGO:00107211690.013
mammary gland morphogenesisGO:0060443540.013
regulation of muscle tissue developmentGO:1901861970.013
meiotic nuclear divisionGO:00071261150.013
rhodopsin mediated signaling pathwayGO:001605640.013
steroid metabolic processGO:00082021190.013
positive regulation of transcription via serum response element bindingGO:001073510.013
regulation of cellular catabolic processGO:00313292420.013
organophosphate catabolic processGO:00464342320.013
organonitrogen compound catabolic processGO:19015652640.013
mapk cascadeGO:00001652810.013
protein secretionGO:00093061110.013
glial cell differentiationGO:00100011310.013
blood vessel morphogenesisGO:00485142850.013
regulation of endocytosisGO:0030100690.013
regulation of saliva secretionGO:004687720.013
negative regulation of epithelial cell proliferationGO:0050680640.013
purine ribonucleotide metabolic processGO:00091502900.013
positive regulation of cyclic nucleotide metabolic processGO:0030801240.013
regulation of stress activated mapk cascadeGO:0032872690.013
positive regulation of fat cell differentiationGO:0045600320.013
actomyosin structure organizationGO:0031032560.013
ribonucleoside metabolic processGO:00091192450.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
water homeostasisGO:0030104270.013
extracellular structure organizationGO:00430621480.013
purine nucleotide biosynthetic processGO:0006164650.012
phospholipase c activating serotonin receptor signaling pathwayGO:000720810.012
cyclic purine nucleotide metabolic processGO:0052652430.012
regulation of protein transportGO:00512231630.012
b cell activationGO:00421131610.012
learningGO:0007612980.012
pharynx developmentGO:006046510.012
lymphocyte differentiationGO:00300982420.012
body fluid secretionGO:0007589530.012
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200260.012
androgen biosynthetic processGO:000670240.012
fat cell differentiationGO:00454441600.012
exploration behaviorGO:0035640210.012
positive regulation of camp metabolic processGO:0030816190.012
adult behaviorGO:00305341350.012
pallium developmentGO:00215431200.012
regulation of protein kinase activityGO:00458592320.012
sodium ion transportGO:0006814730.012
regulation of protein serine threonine kinase activityGO:00719001570.012
regulation of nucleoside metabolic processGO:00091181300.012
establishment of protein localization to organelleGO:00725941180.012
mitotic cell cycleGO:00002781950.012
nucleoside phosphate catabolic processGO:19012922220.012
negative regulation of peptidase activityGO:0010466460.012
positive regulation of purine nucleotide catabolic processGO:0033123880.012
respiratory tube developmentGO:00303231670.011
positive regulation of cytokine biosynthetic processGO:0042108400.011
plasma membrane organizationGO:0007009900.011
regulation of heart growthGO:0060420310.011
small molecule biosynthetic processGO:00442831320.011
mitotic cell cycle processGO:19030471590.011
purine containing compound catabolic processGO:00725232130.011
protein modification by small protein conjugationGO:00324461870.011
positive regulation of protein kinase activityGO:00458601440.011
nucleotide biosynthetic processGO:0009165780.011
organic hydroxy compound transportGO:0015850930.011
negative regulation of cell activationGO:00508661110.011
protein targetingGO:00066051430.011
regulation of cytokine secretionGO:0050707610.011
regulation of homeostatic processGO:00328441820.011
positive regulation of cytosolic calcium ion concentrationGO:0007204650.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
positive regulation of protein secretionGO:0050714520.011
forebrain developmentGO:00309003020.011
establishment of skin barrierGO:0061436140.011
response to retinoic acidGO:0032526560.011
heart inductionGO:000312920.011
somatostatin receptor signaling pathwayGO:003816920.011
regulation of peptidyl serine phosphorylationGO:0033135390.011
pulmonary myocardium developmentGO:000335030.011
response to parathyroid hormoneGO:007110730.011
chromatin organizationGO:00063252060.011
hemostasisGO:0007599780.011
regionalizationGO:00030023370.011
positive regulation of nucleotide catabolic processGO:0030813880.011
modification dependent protein catabolic processGO:00199411330.011
regulation of camp metabolic processGO:0030814300.011
regulation of neuron projection developmentGO:00109751690.011
cellular protein complex assemblyGO:00436231160.011
positive regulation of nervous system developmentGO:00519622210.011
positive regulation of nucleotide biosynthetic processGO:0030810260.010
purine ribonucleoside metabolic processGO:00461282410.010
cellular macromolecule catabolic processGO:00442652060.010
phospholipid metabolic processGO:0006644870.010
gtp catabolic processGO:00061841430.010
ribonucleoside catabolic processGO:00424542060.010
regulation of meiotic cell cycleGO:0051445340.010
negative regulation of response to woundingGO:1903035770.010
cellular component assembly involved in morphogenesisGO:00109271390.010
paraxial mesodermal cell fate commitmentGO:004834320.010
gonad developmentGO:00084061410.010
regulation of cellular carbohydrate metabolic processGO:0010675750.010
nucleotide catabolic processGO:00091662170.010
regulation of sequence specific dna binding transcription factor activityGO:00510901060.010
regulation of proteolysisGO:00301621640.010
interleukin 8 productionGO:003263740.010
regulation of leukocyte differentiationGO:19021051590.010
atrioventricular node cell developmentGO:006092820.010
nuclear divisionGO:00002801580.010
regulation of map kinase activityGO:00434051200.010
carbohydrate derivative catabolic processGO:19011362310.010
negative regulation of protein modification processGO:00314001630.010
cellular response to biotic stimulusGO:0071216920.010
thymus developmentGO:0048538410.010
regulation of sodium ion transportGO:0002028290.010
negative regulation of synapse assemblyGO:005196430.010
rna processingGO:00063961050.010
cardiac ventricle developmentGO:0003231830.010
regulation of circadian rhythmGO:0042752580.010
positive regulation of cell developmentGO:00107202370.010
regulation of purine nucleotide catabolic processGO:00331211220.010
dephosphorylationGO:00163111290.010

Hils1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
eye diseaseDOID:561400.018
eye and adnexa diseaseDOID:149200.018
sensory system diseaseDOID:005015500.018
retinal diseaseDOID:567900.014