Mus musculus

66 known processes

Gphn

gephyrin

(Aliases: GPH,MGC38765,geph,GPHRYN,AI662856,5730552E08Rik,MGC150066,C230040D23,BC027112)

Gphn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleoside phosphate metabolic processGO:00067533380.235
positive regulation of cellular catabolic processGO:00313311480.219
heterocycle catabolic processGO:00467002800.201
transmembrane transportGO:00550854120.195
organonitrogen compound catabolic processGO:19015652640.192
regulation of membrane potentialGO:00423911920.183
ion transmembrane transportGO:00342203610.157
nucleobase containing small molecule metabolic processGO:00550863520.152
nucleoside phosphate catabolic processGO:19012922220.144
purine nucleoside metabolic processGO:00422782410.143
purine nucleoside catabolic processGO:00061522050.140
purine containing compound metabolic processGO:00725213110.137
nucleoside triphosphate catabolic processGO:00091432050.136
aromatic compound catabolic processGO:00194392860.129
nucleotide metabolic processGO:00091173320.121
nucleoside metabolic processGO:00091162460.118
guanosine containing compound metabolic processGO:19010681440.115
purine nucleotide metabolic processGO:00061633020.113
ras protein signal transductionGO:0007265770.112
organic cyclic compound catabolic processGO:19013612950.108
nucleoside catabolic processGO:00091642060.108
organophosphate catabolic processGO:00464342320.102
cellular nitrogen compound catabolic processGO:00442702800.102
glycosyl compound metabolic processGO:19016572460.100
protein catabolic processGO:00301632210.095
macromolecule catabolic processGO:00090572810.094
purine nucleotide catabolic processGO:00061952110.093
small gtpase mediated signal transductionGO:0007264970.093
cell type specific apoptotic processGO:00972852680.091
regulation of cellular catabolic processGO:00313292420.089
carbohydrate derivative catabolic processGO:19011362310.089
ribonucleoside triphosphate metabolic processGO:00091992200.087
regulation of ion transmembrane transportGO:00347651190.080
anion transportGO:00068201770.079
purine containing compound catabolic processGO:00725232130.079
response to oxidative stressGO:00069791230.079
regulation of transmembrane transportGO:00347621280.077
nucleotide catabolic processGO:00091662170.076
protein modification by small protein conjugationGO:00324461870.073
inorganic anion transmembrane transportGO:0098661290.073
inorganic ion transmembrane transportGO:00986602340.071
response to organonitrogen compoundGO:00102432460.070
ribose phosphate metabolic processGO:00196932910.069
neuron apoptotic processGO:00514021420.069
regulation of ras gtpase activityGO:0032318880.069
positive regulation of ras gtpase activityGO:0032320650.069
positive regulation of nucleotide catabolic processGO:0030813880.067
purine nucleoside triphosphate metabolic processGO:00091442260.065
gtp catabolic processGO:00061841430.064
olfactory learningGO:000835520.063
purine ribonucleoside catabolic processGO:00461302050.063
synaptic transmissionGO:00072683290.062
proteolysis involved in cellular protein catabolic processGO:00516031470.061
modification dependent macromolecule catabolic processGO:00436321330.060
action potentialGO:0001508780.060
protein ubiquitinationGO:00165671710.059
forebrain developmentGO:00309003020.059
purine nucleoside triphosphate catabolic processGO:00091462030.059
cognitionGO:00508901490.058
adult locomotory behaviorGO:0008344910.057
purine ribonucleotide catabolic processGO:00091542080.057
ribonucleotide metabolic processGO:00092592910.056
learning or memoryGO:00076111480.055
negative regulation of phosphorus metabolic processGO:00105631840.055
regulation of postsynaptic membrane potentialGO:0060078480.055
nucleoside triphosphate metabolic processGO:00091412300.054
regulation of nucleotide metabolic processGO:00061401690.054
multicellular organismal response to stressGO:0033555620.054
nucleocytoplasmic transportGO:00069131390.053
cytoplasmic transportGO:00164822340.053
peptidyl amino acid modificationGO:00181933360.052
regulation of neuron deathGO:19012141340.051
purine ribonucleotide metabolic processGO:00091502900.051
rho protein signal transductionGO:0007266320.051
positive regulation of nucleotide metabolic processGO:00459811140.051
chloride transmembrane transportGO:1902476240.050
purine ribonucleoside metabolic processGO:00461282410.050
g protein coupled receptor signaling pathwayGO:00071862430.049
negative regulation of intracellular signal transductionGO:19025321670.048
cellular response to growth factor stimulusGO:00713631970.048
cellular amino acid metabolic processGO:00065201030.048
hindbrain developmentGO:00309021280.047
mitochondrion organizationGO:00070051340.046
regulation of nucleotide catabolic processGO:00308111220.046
neuron deathGO:00709971540.046
ribonucleoside metabolic processGO:00091192450.046
telencephalon developmentGO:00215371860.045
regulation of rho protein signal transductionGO:0035023710.045
establishment of mitochondrion localizationGO:005165440.045
cerebellum developmentGO:0021549770.045
purine ribonucleoside triphosphate metabolic processGO:00092052200.045
striated muscle tissue developmentGO:00147062930.045
organelle fissionGO:00482851700.044
cellular response to organonitrogen compoundGO:00714171450.043
cellular macromolecule catabolic processGO:00442652060.043
regulation of rho gtpase activityGO:0032319580.042
glycosyl compound catabolic processGO:19016582060.042
homeostasis of number of cellsGO:00488722100.041
response to growth factorGO:00708481980.041
leukocyte differentiationGO:00025213420.041
response to inorganic substanceGO:0010035960.040
cell divisionGO:00513011200.040
membrane organizationGO:00610242450.039
cellular amino acid catabolic processGO:0009063250.039
ribonucleoside triphosphate catabolic processGO:00092031990.038
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.038
cellular protein catabolic processGO:00442571550.038
regionalizationGO:00030023370.037
gtp metabolic processGO:00460391440.037
regulation of purine nucleotide metabolic processGO:19005421690.037
purine ribonucleoside triphosphate catabolic processGO:00092071990.037
ubiquitin dependent protein catabolic processGO:00065111290.037
oxidation reduction processGO:00551143420.036
locomotory behaviorGO:00076261950.036
positive regulation of rho gtpase activityGO:0032321410.036
cellular ketone metabolic processGO:0042180840.036
regulation of nucleoside metabolic processGO:00091181300.036
carbohydrate metabolic processGO:00059752300.035
positive regulation of ubiquitin protein transferase activityGO:005144340.035
protein polyubiquitinationGO:0000209330.035
regulation of purine nucleotide catabolic processGO:00331211220.034
apoptotic signaling pathwayGO:00971903060.034
response to nutrient levelsGO:00316671090.034
regulation of response to drugGO:200102320.034
regulation of mitochondrial fissionGO:009014030.034
synaptic transmission glycinergicGO:006001220.033
protein modification by small protein conjugation or removalGO:00706472070.033
positive regulation of gtpase activityGO:0043547850.033
regulation of engulfment of apoptotic cellGO:190107420.033
glycerolipid metabolic processGO:00464861220.032
regulation of translationGO:0006417710.032
spermatogenesisGO:00072832840.031
positive regulation of purine nucleotide metabolic processGO:19005441140.031
circadian rhythmGO:00076231140.031
response to uvGO:0009411440.030
regulation of cell motilityGO:20001452360.030
regulation of organelle organizationGO:00330432890.030
negative regulation of phosphate metabolic processGO:00459361840.030
cellular lipid metabolic processGO:00442553230.029
gland developmentGO:00487323300.029
single fertilizationGO:0007338820.029
regulation of ion transportGO:00432692150.029
negative regulation of cellular protein metabolic processGO:00322692470.029
positive regulation of nucleoside metabolic processGO:0045979910.029
renal system developmentGO:00720012250.029
ribonucleoside catabolic processGO:00424542060.028
fertilizationGO:00095661270.028
intrinsic apoptotic signaling pathwayGO:00971931320.028
lipid biosynthetic processGO:00086101790.028
regulation of ras protein signal transductionGO:00465781140.027
cellular response to ammonium ionGO:007124220.027
regulation of neuron apoptotic processGO:00435231220.027
blood vessel morphogenesisGO:00485142850.027
covalent chromatin modificationGO:00165691630.027
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.027
proteasomal protein catabolic processGO:0010498980.027
regulation of transferase activityGO:00513382630.027
learningGO:0007612980.027
response to transforming growth factor betaGO:0071559880.026
monocarboxylic acid metabolic processGO:00327871910.026
positive regulation of protein modification processGO:00314012990.026
exocytosisGO:00068871210.026
positive regulation of growthGO:00459271040.026
transforming growth factor beta receptor signaling pathwayGO:0007179710.026
muscle cell differentiationGO:00426922610.026
cellular chemical homeostasisGO:00550822150.025
chloride transportGO:0006821320.025
intracellular protein transportGO:00068862040.025
translationGO:0006412930.025
mitochondrion transport along microtubuleGO:004749730.024
response to radiationGO:00093141650.024
neuron neuron synaptic transmissionGO:0007270690.024
regulation of cellular ketone metabolic processGO:0010565660.024
metencephalon developmentGO:0022037890.024
negative regulation of neuron apoptotic processGO:0043524920.024
negative regulation of apoptotic signaling pathwayGO:20012341040.024
positive regulation of cellular amine metabolic processGO:003324050.023
nitrogen compound transportGO:00717052710.023
regulation of protein catabolic processGO:00421761080.023
positive regulation of hydrolase activityGO:00513451480.023
positive regulation of cell developmentGO:00107202370.023
rhythmic processGO:00485111740.023
response to drugGO:0042493750.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
ossificationGO:00015032160.022
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.022
regulation of ubiquitin protein transferase activityGO:005143870.022
regulation of anion transportGO:0044070270.022
endomembrane system organizationGO:00102561470.022
regulation of protein ubiquitinationGO:0031396520.022
protein localization to membraneGO:00726571080.022
cellular amine metabolic processGO:0044106440.022
negative regulation of protein metabolic processGO:00512482820.022
alcohol metabolic processGO:00060661160.022
epithelial cell developmentGO:00020641590.021
regulation of kinase activityGO:00435492490.021
positive regulation of transferase activityGO:00513471670.021
dephosphorylationGO:00163111290.021
positive regulation of purine nucleotide catabolic processGO:0033123880.021
lipid localizationGO:00108761260.021
guanosine containing compound catabolic processGO:19010691440.021
compound eye developmentGO:004874910.021
mapk cascadeGO:00001652810.021
transmission of nerve impulseGO:0019226760.021
inorganic anion transportGO:0015698430.021
skeletal system developmentGO:00015013560.020
neuronal action potentialGO:0019228540.020
sensory perceptionGO:00076002450.020
nuclear transportGO:00511691390.020
cation transportGO:00068123990.020
response to osmotic stressGO:0006970210.020
myosin filament assemblyGO:003103420.020
negative regulation of cell sizeGO:004579230.020
divalent inorganic cation transportGO:00725111780.020
anion transmembrane transportGO:0098656710.020
adult behaviorGO:00305341350.020
regulation of hydrolase activityGO:00513362460.019
monocarboxylic acid biosynthetic processGO:0072330610.019
regulation of synaptic plasticityGO:0048167870.019
modification dependent protein catabolic processGO:00199411330.019
cellular homeostasisGO:00197252400.019
neuromuscular processGO:0050905990.019
response to organic cyclic compoundGO:00140701980.019
defecationGO:003042110.019
regulation of feeding behaviorGO:006025930.019
regulation of ion transmembrane transporter activityGO:0032412540.019
response to endoplasmic reticulum stressGO:0034976530.019
positive regulation of organelle organizationGO:00106381280.019
fatty acid metabolic processGO:00066311210.019
regulation of protein modification by small protein conjugation or removalGO:1903320570.019
fat cell differentiationGO:00454441600.019
cellular response to arsenic containing substanceGO:007124340.019
negative regulation of immune system processGO:00026832090.019
protein localization to organelleGO:00333651850.019
negative regulation of phosphorylationGO:00423261660.019
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.019
male gamete generationGO:00482322850.019
glycerolipid biosynthetic processGO:0045017500.018
multicellular organism growthGO:00352641610.018
cellular response to histamineGO:007142010.018
organonitrogen compound biosynthetic processGO:19015661920.018
chromatin modificationGO:00165681870.018
organic acid catabolic processGO:0016054510.018
regulation of lymphocyte activationGO:00512492400.018
response to extracellular stimulusGO:00099911270.018
regulation of apoptotic signaling pathwayGO:20012331970.018
cation homeostasisGO:00550802120.018
regulation of system processGO:00440572000.018
regulation of proteolysisGO:00301621640.018
regulation of cell cycleGO:00517262810.018
regulation of cell projection organizationGO:00313442060.017
cellular ion homeostasisGO:00068731650.017
associative learningGO:0008306610.017
sensory perception of light stimulusGO:0050953540.017
lymphocyte differentiationGO:00300982420.017
response to metal ionGO:0010038470.017
amine metabolic processGO:0009308450.017
negative regulation of neuron deathGO:1901215980.017
lipid homeostasisGO:0055088630.017
regulation of transporter activityGO:0032409570.017
establishment of protein localization to organelleGO:00725941180.017
cellular response to biotic stimulusGO:0071216920.017
cell maturationGO:00484691270.017
carbohydrate derivative biosynthetic processGO:19011371830.017
divalent metal ion transportGO:00708381720.017
cellular response to amino acid stimulusGO:0071230290.017
cellular response to transforming growth factor beta stimulusGO:0071560880.017
multi multicellular organism processGO:00447061090.016
multicellular organismal signalingGO:0035637910.016
regulation of cell activationGO:00508652890.016
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.016
cell adhesionGO:00071553290.016
urogenital system developmentGO:00016552610.016
protein targetingGO:00066051430.016
chromatin organizationGO:00063252060.016
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.016
cofactor biosynthetic processGO:0051188410.016
regulation of release of cytochrome c from mitochondriaGO:0090199110.016
memoryGO:0007613580.016
connective tissue developmentGO:00614481790.016
positive regulation of cell activationGO:00508671580.016
regulation of respiratory system processGO:0044065130.016
tube formationGO:00351481400.016
inorganic cation transmembrane transportGO:00986622070.016
visual perceptionGO:0007601520.015
morphogenesis of embryonic epitheliumGO:00163311590.015
cofactor metabolic processGO:0051186800.015
alpha amino acid metabolic processGO:1901605590.015
regulation of cell divisionGO:0051302760.015
microtubule based movementGO:0007018840.015
metal ion homeostasisGO:00550651890.015
cation transmembrane transportGO:00986552660.015
cellular carbohydrate metabolic processGO:00442621190.015
regulation of protein localizationGO:00328802310.015
regulation of lipid metabolic processGO:00192161180.015
transition metal ion homeostasisGO:0055076540.015
camera type eye developmentGO:00430102660.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
central nervous system neuron differentiationGO:00219531620.014
ear developmentGO:00435832000.014
protein oligomerizationGO:0051259670.014
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.014
regulation of mapk cascadeGO:00434082480.014
sulfur compound metabolic processGO:00067901000.014
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.014
nuclear divisionGO:00002801580.014
coenzyme biosynthetic processGO:0009108230.014
digestive system developmentGO:00551232000.014
response to molecule of bacterial originGO:00022371430.014
epithelial cell proliferationGO:00506731740.014
positive regulation of protein ubiquitinationGO:0031398270.014
myeloid cell homeostasisGO:00022621140.014
respiratory gaseous exchangeGO:0007585430.014
female gamete generationGO:0007292740.014
cellular response to hormone stimulusGO:00328701500.014
germ cell developmentGO:00072811850.014
muscle tissue developmentGO:00605373080.014
regulation of neuron differentiationGO:00456642810.014
maintenance of locationGO:0051235890.014
cerebellum morphogenesisGO:0021587420.014
oocyte anterior posterior axis specificationGO:000731420.014
primary neural tube formationGO:0014020950.014
negative regulation of mapk cascadeGO:0043409650.013
neural tube developmentGO:00219151600.013
regulation of defense responseGO:00313472330.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
negative regulation of cell proliferationGO:00082852960.013
regulation of cellular component biogenesisGO:00440871810.013
regulation of mitochondrion organizationGO:0010821270.013
regulation of ossificationGO:00302781120.013
phagocytosisGO:0006909660.013
maternal determination of anterior posterior axis embryoGO:000835820.013
actin cytoskeleton organizationGO:00300362200.013
inner ear receptor cell differentiationGO:0060113610.013
posttranscriptional regulation of gene expressionGO:00106081550.013
neural precursor cell proliferationGO:00613511210.013
energy reserve metabolic processGO:0006112390.013
mitochondrion distributionGO:004831140.013
respiratory system processGO:0003016250.013
organelle localizationGO:00516401790.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.013
p38mapk cascadeGO:003806640.013
glycerophospholipid metabolic processGO:0006650710.013
myelinationGO:0042552740.012
sensory perception of mechanical stimulusGO:00509541070.012
cellular response to acid chemicalGO:0071229680.012
nuclear exportGO:0051168340.012
innate immune responseGO:00450871570.012
regulation of leukocyte differentiationGO:19021051590.012
mrna processingGO:0006397630.012
oocyte constructionGO:000730820.012
regulation of epithelial cell proliferationGO:00506781410.012
regulation of myeloid cell differentiationGO:0045637960.012
dna metabolic processGO:00062593030.012
limbic system developmentGO:0021761720.012
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.012
negative regulation of organelle organizationGO:0010639900.012
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.012
positive regulation of mitotic sister chromatid separationGO:190197020.012
glucose homeostasisGO:00425931280.012
calcium ion transportGO:00068161590.012
calcium ion transmembrane transportGO:0070588850.012
cellular response to dna damage stimulusGO:00069742070.012
alpha amino acid catabolic processGO:1901606180.012
positive regulation of protein phosphorylationGO:00019342420.012
regulation of respiratory gaseous exchange by neurological system processGO:0002087120.012
regulation of protein kinase activityGO:00458592320.012
histone modificationGO:00165701590.012
negative regulation of cellular component organizationGO:00511291940.011
nucleoside monophosphate metabolic processGO:0009123850.011
embryonic organ morphogenesisGO:00485622760.011
striated muscle cell developmentGO:00550021250.011
meiotic nuclear divisionGO:00071261150.011
carboxylic acid catabolic processGO:0046395510.011
ensheathment of neuronsGO:0007272760.011
cellular alcohol metabolic processGO:004410730.011
intracellular mrna localizationGO:000829840.011
nucleoside phosphate biosynthetic processGO:1901293790.011
wnt signaling pathwayGO:00160551880.011
reactive oxygen species biosynthetic processGO:190340980.011
lymphocyte proliferationGO:00466511640.011
anatomical structure homeostasisGO:00602491450.011
respiratory system developmentGO:00605411900.011
phospholipid metabolic processGO:0006644870.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
regulation of homeostatic processGO:00328441820.011
regulation of respiratory gaseous exchangeGO:0043576180.011
regulation of cellular protein catabolic processGO:1903362610.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
meiotic cell cycleGO:00513211220.011
neural tube formationGO:00018411080.011
regulation of cytokine productionGO:00018172660.011
t cell activationGO:00421102890.011
polysaccharide metabolic processGO:0005976390.011
regulation of cell migrationGO:00303342190.011
phosphatidylinositol metabolic processGO:0046488450.011
regulation of chromosome organizationGO:0033044830.011
regulation of androgen receptor signaling pathwayGO:006076530.011
cellular response to cytokine stimulusGO:00713451890.011
negative regulation of cellular response to growth factor stimulusGO:0090288460.011
cellular response to lipopolysaccharideGO:0071222770.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
epithelial tube morphogenesisGO:00605623030.011
dna repairGO:00062811070.011
insulin metabolic processGO:190114230.010
glycoprotein metabolic processGO:00091001160.010
regulation of protein transportGO:00512231630.010
regulation of secretion by cellGO:19035302490.010
protein export from nucleusGO:0006611200.010
multicellular organismal homeostasisGO:00488711640.010
organic acid biosynthetic processGO:0016053860.010
response to lipopolysaccharideGO:00324961280.010
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.010
regulation of secretionGO:00510462740.010
negative regulation of mesenchymal cell proliferationGO:007220130.010
response to amino acidGO:0043200370.010
myeloid leukocyte differentiationGO:00025731190.010
dendrite developmentGO:00163581150.010
cell fate commitmentGO:00451652100.010
defense response to other organismGO:00985421970.010
positive regulation of ion transportGO:0043270650.010
purine nucleoside monophosphate metabolic processGO:0009126810.010

Gphn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.031
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
inherited metabolic disorderDOID:65500.013
musculoskeletal system diseaseDOID:1700.011
cancerDOID:16200.010
disease of cellular proliferationDOID:1456600.010