| cation transmembrane transport | GO:0098655 | 266 | 0.227 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.203 | |
| transmembrane transport | GO:0055085 | 412 | 0.180 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.177 | |
| cation transport | GO:0006812 | 399 | 0.149 | |
| single fertilization | GO:0007338 | 82 | 0.131 | |
| cytokine production | GO:0001816 | 319 | 0.106 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.097 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.071 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.071 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.067 | |
| fertilization | GO:0009566 | 127 | 0.067 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.058 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.058 | |
| regulation of feeding behavior | GO:0060259 | 3 | 0.053 | |
| defense response to bacterium | GO:0042742 | 119 | 0.053 | |
| circulatory system process | GO:0003013 | 197 | 0.052 | |
| membrane organization | GO:0061024 | 245 | 0.050 | |
| regulation of thyroid hormone generation | GO:2000609 | 4 | 0.048 | |
| synaptic transmission | GO:0007268 | 329 | 0.048 | |
| regulation of defense response | GO:0031347 | 233 | 0.048 | |
| action potential | GO:0001508 | 78 | 0.045 | |
| t cell activation | GO:0042110 | 289 | 0.044 | |
| associative learning | GO:0008306 | 61 | 0.044 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.044 | |
| maintenance of location | GO:0051235 | 89 | 0.044 | |
| immune effector process | GO:0002252 | 321 | 0.044 | |
| binding of sperm to zona pellucida | GO:0007339 | 34 | 0.043 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.042 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.042 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.040 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.040 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.038 | |
| axonogenesis | GO:0007409 | 274 | 0.037 | |
| learning or memory | GO:0007611 | 148 | 0.035 | |
| regulation of blood pressure | GO:0008217 | 93 | 0.035 | |
| regulation of system process | GO:0044057 | 200 | 0.034 | |
| inflammatory response | GO:0006954 | 244 | 0.034 | |
| regulation of cell activation | GO:0050865 | 289 | 0.034 | |
| calcium ion transmembrane transport | GO:0070588 | 85 | 0.034 | |
| positive regulation of ion transport | GO:0043270 | 65 | 0.033 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.033 | |
| urogenital system development | GO:0001655 | 261 | 0.033 | |
| regulation of secretion | GO:0051046 | 274 | 0.033 | |
| cognition | GO:0050890 | 149 | 0.032 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.032 | |
| locomotory behavior | GO:0007626 | 195 | 0.032 | |
| innate immune response | GO:0045087 | 157 | 0.032 | |
| learning | GO:0007612 | 98 | 0.031 | |
| cell cell recognition | GO:0009988 | 44 | 0.031 | |
| anion transport | GO:0006820 | 177 | 0.031 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.031 | |
| hair follicle development | GO:0001942 | 85 | 0.030 | |
| epidermis development | GO:0008544 | 187 | 0.030 | |
| blood circulation | GO:0008015 | 195 | 0.030 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.030 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.030 | |
| regulation of circadian sleep wake cycle | GO:0042749 | 3 | 0.029 | |
| striated muscle contraction | GO:0006941 | 45 | 0.029 | |
| anion transmembrane transport | GO:0098656 | 71 | 0.029 | |
| amine metabolic process | GO:0009308 | 45 | 0.028 | |
| sensory perception of light stimulus | GO:0050953 | 54 | 0.028 | |
| carboxylic acid transport | GO:0046942 | 100 | 0.028 | |
| muscle system process | GO:0003012 | 141 | 0.028 | |
| neuronal action potential | GO:0019228 | 54 | 0.027 | |
| mapk cascade | GO:0000165 | 281 | 0.027 | |
| oxidation reduction process | GO:0055114 | 342 | 0.026 | |
| sperm egg recognition | GO:0035036 | 37 | 0.026 | |
| conditioned taste aversion | GO:0001661 | 4 | 0.026 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.025 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.025 | |
| pilomotor reflex | GO:0097195 | 3 | 0.025 | |
| sa node cell action potential | GO:0086015 | 4 | 0.025 | |
| protein maturation | GO:0051604 | 176 | 0.025 | |
| response to light stimulus | GO:0009416 | 135 | 0.024 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.024 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.024 | |
| negative regulation of defense response | GO:0031348 | 77 | 0.024 | |
| cation homeostasis | GO:0055080 | 212 | 0.024 | |
| feeding behavior | GO:0007631 | 62 | 0.023 | |
| cell adhesion | GO:0007155 | 329 | 0.023 | |
| monovalent inorganic cation homeostasis | GO:0055067 | 33 | 0.023 | |
| response to oxygen levels | GO:0070482 | 62 | 0.023 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.023 | |
| av node cell to bundle of his cell communication | GO:0086067 | 2 | 0.023 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.023 | |
| response to peptide hormone | GO:0043434 | 127 | 0.022 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.022 | |
| muscle contraction | GO:0006936 | 101 | 0.022 | |
| developmental maturation | GO:0021700 | 193 | 0.022 | |
| regulation of muscle contraction | GO:0006937 | 49 | 0.022 | |
| adult behavior | GO:0030534 | 135 | 0.022 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.022 | |
| response to peptide | GO:1901652 | 136 | 0.022 | |
| exocytosis | GO:0006887 | 121 | 0.021 | |
| regulation of muscle tissue development | GO:1901861 | 97 | 0.021 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.021 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.021 | |
| positive regulation of thyroid hormone generation | GO:2000611 | 2 | 0.021 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.021 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.021 | |
| protein catabolic process | GO:0030163 | 221 | 0.021 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.021 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.020 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.020 | |
| calcium ion dependent exocytosis | GO:0017156 | 35 | 0.020 | |
| regulation of renin secretion into blood stream | GO:1900133 | 4 | 0.020 | |
| response to radiation | GO:0009314 | 165 | 0.020 | |
| neuron neuron synaptic transmission | GO:0007270 | 69 | 0.020 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.020 | |
| regulation of ph | GO:0006885 | 26 | 0.020 | |
| developmental cell growth | GO:0048588 | 84 | 0.020 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.020 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.020 | |
| asymmetric stem cell division | GO:0098722 | 3 | 0.020 | |
| regulation of systemic arterial blood pressure | GO:0003073 | 61 | 0.019 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.019 | |
| digestion | GO:0007586 | 40 | 0.019 | |
| muscle tissue development | GO:0060537 | 308 | 0.019 | |
| digestive system development | GO:0055123 | 200 | 0.019 | Mouse |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.019 | |
| cellular homeostasis | GO:0019725 | 240 | 0.019 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.019 | |
| renal system development | GO:0072001 | 225 | 0.019 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.019 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.019 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.019 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.019 | |
| cellular potassium ion transport | GO:0071804 | 43 | 0.019 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.018 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.018 | |
| sensory perception of sound | GO:0007605 | 97 | 0.018 | |
| endomembrane system organization | GO:0010256 | 147 | 0.018 | |
| skin development | GO:0043588 | 220 | 0.018 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.018 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.017 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.017 | |
| axon ensheathment | GO:0008366 | 76 | 0.017 | |
| actin filament based movement | GO:0030048 | 23 | 0.017 | |
| regulation of neurotransmitter levels | GO:0001505 | 87 | 0.017 | |
| placenta development | GO:0001890 | 140 | 0.017 | |
| hormone metabolic process | GO:0042445 | 86 | 0.017 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.017 | |
| cellular response to nutrient levels | GO:0031669 | 64 | 0.017 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.017 | |
| male gamete generation | GO:0048232 | 285 | 0.017 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.017 | |
| prevention of polyspermy | GO:0060468 | 4 | 0.017 | |
| vitamin transmembrane transport | GO:0035461 | 4 | 0.017 | |
| organ growth | GO:0035265 | 117 | 0.017 | |
| amino acid transport | GO:0006865 | 61 | 0.017 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.017 | |
| response to inorganic substance | GO:0010035 | 96 | 0.017 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.016 | |
| cell growth | GO:0016049 | 130 | 0.016 | |
| heart morphogenesis | GO:0003007 | 178 | 0.016 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.016 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.016 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.016 | |
| spermatogenesis | GO:0007283 | 284 | 0.016 | |
| sa node cell to atrial cardiac muscle cell signalling | GO:0086018 | 4 | 0.016 | |
| inorganic anion transport | GO:0015698 | 43 | 0.016 | |
| protein processing | GO:0016485 | 163 | 0.016 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.016 | |
| camera type eye development | GO:0043010 | 266 | 0.016 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.016 | |
| organelle localization | GO:0051640 | 179 | 0.016 | |
| leukocyte homeostasis | GO:0001776 | 79 | 0.015 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.015 | |
| developmental growth involved in morphogenesis | GO:0060560 | 138 | 0.015 | |
| regulation of circadian sleep wake cycle sleep | GO:0045187 | 3 | 0.015 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.015 | |
| cell communication by chemical coupling | GO:0010643 | 2 | 0.015 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.015 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.015 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.015 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.015 | |
| cellular response to starvation | GO:0009267 | 57 | 0.015 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.015 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.015 | |
| regulation of t cell proliferation | GO:0042129 | 92 | 0.015 | |
| thyroid hormone metabolic process | GO:0042403 | 16 | 0.015 | |
| tissue remodeling | GO:0048771 | 102 | 0.015 | |
| ventricular cardiac muscle cell action potential | GO:0086005 | 4 | 0.015 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.015 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.015 | |
| visual perception | GO:0007601 | 52 | 0.014 | |
| kidney development | GO:0001822 | 213 | 0.014 | |
| sodium ion transport | GO:0006814 | 73 | 0.014 | |
| renal system process | GO:0003014 | 48 | 0.014 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.014 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.014 | |
| sensory perception of mechanical stimulus | GO:0050954 | 107 | 0.014 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.014 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.014 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.014 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.014 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.014 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.014 | |
| cardiac muscle contraction | GO:0060048 | 32 | 0.014 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.014 | |
| protein localization to membrane | GO:0072657 | 108 | 0.014 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.014 | |
| vesicle organization | GO:0016050 | 60 | 0.014 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.014 | |
| cell recognition | GO:0008037 | 83 | 0.014 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.014 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.013 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.013 | |
| regulation of blood circulation | GO:1903522 | 93 | 0.013 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.013 | |
| regulation of cell motility | GO:2000145 | 236 | 0.013 | |
| glucose transport | GO:0015758 | 56 | 0.013 | |
| organic anion transport | GO:0015711 | 137 | 0.013 | |
| protein polymerization | GO:0051258 | 57 | 0.013 | |
| regulation of mesenchymal cell proliferation involved in ureter development | GO:0072199 | 3 | 0.013 | |
| membrane fusion | GO:0061025 | 38 | 0.013 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.013 | |
| positive regulation of the force of heart contraction by epinephrine norepinephrine | GO:0001997 | 3 | 0.013 | |
| monosaccharide metabolic process | GO:0005996 | 106 | 0.013 | |
| adult locomotory behavior | GO:0008344 | 91 | 0.013 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.013 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.013 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.013 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.013 | |
| embryonic placenta development | GO:0001892 | 98 | 0.013 | |
| potassium ion homeostasis | GO:0055075 | 4 | 0.013 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.013 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.013 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.012 | |
| peripheral nervous system development | GO:0007422 | 53 | 0.012 | |
| sodium ion transmembrane transport | GO:0035725 | 49 | 0.012 | |
| negative regulation of inflammatory response | GO:0050728 | 61 | 0.012 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.012 | |
| skeletal system development | GO:0001501 | 356 | 0.012 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.012 | |
| positive regulation of synaptic growth at neuromuscular junction | GO:0045887 | 1 | 0.012 | |
| organic hydroxy compound transport | GO:0015850 | 93 | 0.012 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.012 | |
| response to insulin | GO:0032868 | 100 | 0.012 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.012 | |
| negative regulation of epithelial cell proliferation | GO:0050680 | 64 | 0.012 | |
| oligopeptide transmembrane transport | GO:0035672 | 4 | 0.012 | |
| response to growth factor | GO:0070848 | 198 | 0.012 | |
| dephosphorylation | GO:0016311 | 129 | 0.012 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.012 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.012 | |
| positive regulation of homeostatic process | GO:0032846 | 64 | 0.012 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.012 | |
| wound healing | GO:0042060 | 157 | 0.012 | |
| sensory perception | GO:0007600 | 245 | 0.012 | |
| cardiac muscle tissue development | GO:0048738 | 130 | 0.012 | |
| cellular response to insulin stimulus | GO:0032869 | 78 | 0.012 | |
| ascending thin limb development | GO:0072021 | 2 | 0.012 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.012 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.012 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.012 | |
| cellular modified amino acid metabolic process | GO:0006575 | 63 | 0.011 | |
| reflex | GO:0060004 | 22 | 0.011 | |
| cardiac muscle cell contraction | GO:0086003 | 7 | 0.011 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.011 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.011 | |
| interleukin 10 secretion | GO:0072608 | 4 | 0.011 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.011 | |
| response to hypoxia | GO:0001666 | 58 | 0.011 | |
| calcium ion transport | GO:0006816 | 159 | 0.011 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.011 | |
| regulation of protein localization | GO:0032880 | 231 | 0.011 | |
| regulation of protein processing | GO:0070613 | 96 | 0.011 | |
| intracellular protein transport | GO:0006886 | 204 | 0.011 | |
| defecation | GO:0030421 | 1 | 0.011 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.011 | |
| cellular response to lipid | GO:0071396 | 145 | 0.011 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.011 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.011 | |
| angiogenesis | GO:0001525 | 201 | 0.011 | |
| synaptic vesicle localization | GO:0097479 | 59 | 0.011 | |
| establishment or maintenance of neuroblast polarity | GO:0045196 | 1 | 0.011 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.011 | |
| alpha beta t cell activation | GO:0046631 | 91 | 0.011 | |
| positive regulation of growth | GO:0045927 | 104 | 0.011 | |
| single organismal cell cell adhesion | GO:0016337 | 131 | 0.011 | |
| visual learning | GO:0008542 | 44 | 0.011 | |
| regulation of muscle system process | GO:0090257 | 80 | 0.011 | |
| neuron projection extension | GO:1990138 | 64 | 0.011 | |
| response to steroid hormone | GO:0048545 | 56 | 0.011 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.011 | |
| response to decreased oxygen levels | GO:0036293 | 59 | 0.011 | |
| hair cycle | GO:0042633 | 90 | 0.011 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 71 | 0.011 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.011 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.010 | |
| regulation of ion transport | GO:0043269 | 215 | 0.010 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.010 | |
| neutral lipid metabolic process | GO:0006638 | 57 | 0.010 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.010 | |
| rna processing | GO:0006396 | 105 | 0.010 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.010 | |
| connective tissue development | GO:0061448 | 179 | 0.010 | |
| neurotransmitter secretion | GO:0007269 | 62 | 0.010 | |
| positive regulation of lymphocyte differentiation | GO:0045621 | 61 | 0.010 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.010 | |
| regulation of cell size | GO:0008361 | 72 | 0.010 | |
| cytokine metabolic process | GO:0042107 | 71 | 0.010 | |
| spleen development | GO:0048536 | 39 | 0.010 | |
| fat soluble vitamin biosynthetic process | GO:0042362 | 4 | 0.010 | |
| striated muscle cell development | GO:0055002 | 125 | 0.010 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.010 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.010 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.010 | |
| regulation of lipid metabolic process | GO:0019216 | 118 | 0.010 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.010 | |
| norepinephrine transport | GO:0015874 | 2 | 0.010 | |
| protein localization to organelle | GO:0033365 | 185 | 0.010 | |
| cellular alcohol biosynthetic process | GO:0044108 | 3 | 0.010 | |
| hexose metabolic process | GO:0019318 | 98 | 0.010 | |
| response to starvation | GO:0042594 | 65 | 0.010 | |
| atrial ventricular junction remodeling | GO:0003294 | 2 | 0.010 | |