Mus musculus

39 known processes

Espl1

extra spindle poles-like 1 (S. cerevisiae)

(Aliases: AL024103,PRCE,Cerp,SSE,ESP1,AU045071)

Espl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.260
chromatin organizationGO:00063252060.135
chromosome segregationGO:0007059480.130
microtubule polymerization or depolymerizationGO:0031109260.119
dna repairGO:00062811070.105
positive regulation of chromosome segregationGO:005198440.098
regulation of exit from mitosisGO:000709610.084
microtubule cytoskeleton organization involved in mitosisGO:190285040.082
regulation of organelle organizationGO:00330432890.072
meiotic cell cycleGO:00513211220.071
macromolecule catabolic processGO:00090572810.071
male gamete generationGO:00482322850.069
nuclear divisionGO:00002801580.067
cellular protein catabolic processGO:00442571550.067
regulation of cellular amine metabolic processGO:0033238200.066
meiotic nuclear divisionGO:00071261150.063
negative regulation of cellular protein metabolic processGO:00322692470.063
meiotic cell cycle processGO:1903046770.062
heterocycle catabolic processGO:00467002800.061
cellular response to dna damage stimulusGO:00069742070.058
protein modification by small protein conjugation or removalGO:00706472070.057
organophosphate catabolic processGO:00464342320.056
regulation of cellular amino acid metabolic processGO:000652150.056
purine ribonucleoside metabolic processGO:00461282410.055
organelle assemblyGO:00709251770.055
organelle fissionGO:00482851700.055
nucleoside triphosphate metabolic processGO:00091412300.054
cellular amine metabolic processGO:0044106440.052
positive regulation of mitotic sister chromatid separationGO:190197020.052
regulation of cellular catabolic processGO:00313292420.052
amine metabolic processGO:0009308450.051
positive regulation of cellular amine metabolic processGO:003324050.051
positive regulation of cellular amino acid metabolic processGO:004576430.049
cell divisionGO:00513011200.049
negative regulation of protein metabolic processGO:00512482820.049
male meiosisGO:0007140370.048
dna recombinationGO:0006310920.047
protein polymerizationGO:0051258570.046
protein processingGO:00164851630.046
peptidyl amino acid modificationGO:00181933360.046
protein catabolic processGO:00301632210.044
ribonucleoside metabolic processGO:00091192450.044
protein ubiquitinationGO:00165671710.044
organic cyclic compound catabolic processGO:19013612950.044
regulation of cell cycleGO:00517262810.043
negative regulation of molecular functionGO:00440922580.042
ribonucleotide metabolic processGO:00092592910.042
purine ribonucleotide metabolic processGO:00091502900.042
cellular amino acid metabolic processGO:00065201030.041
protein modification by small protein conjugationGO:00324461870.041
mitotic cytokinesisGO:000028140.041
asymmetric stem cell divisionGO:009872230.040
lateral inhibitionGO:004633110.040
metaphase plate congressionGO:005131020.039
purine nucleoside catabolic processGO:00061522050.039
cellular ketone metabolic processGO:0042180840.038
regulation of protein processingGO:0070613960.037
regulation of cellular ketone metabolic processGO:0010565660.036
negative regulation of phosphorus metabolic processGO:00105631840.036
purine containing compound metabolic processGO:00725213110.035
cellular macromolecule catabolic processGO:00442652060.035
cellular nitrogen compound catabolic processGO:00442702800.034
nucleoside catabolic processGO:00091642060.034
regulation of chromosome organizationGO:0033044830.034
positive regulation of mitotic metaphase anaphase transitionGO:004584220.034
regulation of cell cycle processGO:00105641600.034
purine nucleotide metabolic processGO:00061633020.034
regulation of transferase activityGO:00513382630.033
nucleobase containing small molecule metabolic processGO:00550863520.033
purine ribonucleoside catabolic processGO:00461302050.033
positive regulation of protein modification processGO:00314012990.033
protein localization to organelleGO:00333651850.033
nucleoside phosphate catabolic processGO:19012922220.033
covalent chromatin modificationGO:00165691630.032
positive regulation of protein phosphorylationGO:00019342420.032
spermatogenesisGO:00072832840.032
chromatin modificationGO:00165681870.032
carbohydrate derivative catabolic processGO:19011362310.032
organelle localizationGO:00516401790.031
proteolysis involved in cellular protein catabolic processGO:00516031470.030
regulation of protein kinase activityGO:00458592320.030
nucleotide metabolic processGO:00091173320.030
spindle assembly involved in mitosisGO:009030740.029
purine containing compound catabolic processGO:00725232130.029
ribonucleoside triphosphate catabolic processGO:00092031990.029
positive regulation of protein kinase activityGO:00458601440.028
mitotic cell cycleGO:00002781950.028
nucleoside metabolic processGO:00091162460.028
protein maturationGO:00516041760.027
synaptic transmissionGO:00072683290.027
mitotic cell cycle processGO:19030471590.027
cation transportGO:00068123990.027
modification dependent protein catabolic processGO:00199411330.027
nucleoside phosphate metabolic processGO:00067533380.026
purine nucleoside triphosphate metabolic processGO:00091442260.026
proteasomal protein catabolic processGO:0010498980.026
positive regulation of cell divisionGO:0051781310.026
ribonucleoside triphosphate metabolic processGO:00091992200.026
purine ribonucleoside triphosphate metabolic processGO:00092052200.026
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.026
cellular homeostasisGO:00197252400.026
negative regulation of cell proliferationGO:00082852960.026
regulation of proteolysisGO:00301621640.025
endocytosisGO:00068971680.024
metaphase anaphase transition of mitotic cell cycleGO:000709190.024
positive regulation of metaphase anaphase transition of cell cycleGO:190210120.024
aromatic compound catabolic processGO:00194392860.024
negative regulation of protein modification processGO:00314001630.024
regulation of chromatin silencingGO:003193520.024
nucleoside triphosphate catabolic processGO:00091432050.023
negative regulation of proteolysisGO:0045861740.023
purine ribonucleotide catabolic processGO:00091542080.023
nitrogen compound transportGO:00717052710.023
double strand break repairGO:0006302480.023
sister chromatid segregationGO:0000819200.023
transmembrane transportGO:00550854120.023
regulation of neuron differentiationGO:00456642810.023
purine nucleoside triphosphate catabolic processGO:00091462030.022
cleavage furrow formationGO:003608920.022
synaptonemal complex organizationGO:0070193150.022
regulation of cytokine productionGO:00018172660.021
regulation of protein maturationGO:1903317960.021
regulation of secretion by cellGO:19035302490.021
peptidyl serine phosphorylationGO:0018105740.021
gland developmentGO:00487323300.021
ribose phosphate metabolic processGO:00196932910.021
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.021
cell fate commitmentGO:00451652100.021
regulation of mitotic cell cycle phase transitionGO:1901990730.020
gene silencingGO:0016458380.020
regulation of secretionGO:00510462740.020
histone modificationGO:00165701590.020
regulation of kinase activityGO:00435492490.020
positive regulation of transferase activityGO:00513471670.020
organonitrogen compound catabolic processGO:19015652640.020
meiosis iGO:0007127600.020
purine nucleotide catabolic processGO:00061952110.020
g1 s transition of mitotic cell cycleGO:0000082570.020
negative regulation of phosphate metabolic processGO:00459361840.020
lymphocyte differentiationGO:00300982420.019
positive regulation of organelle organizationGO:00106381280.019
protein complex disassemblyGO:0043241400.019
mapk cascadeGO:00001652810.019
regulation of cell projection organizationGO:00313442060.019
ubiquitin dependent protein catabolic processGO:00065111290.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
regulation of homeostatic processGO:00328441820.019
regulation of protein transportGO:00512231630.019
negative regulation of cellular catabolic processGO:0031330470.019
small gtpase mediated signal transductionGO:0007264970.019
negative regulation of chromatin silencingGO:003193610.019
regulation of mrna processingGO:0050684410.019
base excision repair gap fillingGO:000628730.019
maintenance of locationGO:0051235890.018
reactive oxygen species metabolic processGO:0072593840.018
regulation of mitotic cell cycleGO:00073461260.018
oogenesisGO:0048477560.018
positive regulation of cellular catabolic processGO:00313311480.018
ribonucleoside catabolic processGO:00424542060.018
chromosome separationGO:0051304140.018
anatomical structure homeostasisGO:00602491450.018
leukocyte differentiationGO:00025213420.018
purine ribonucleoside monophosphate metabolic processGO:0009167800.018
cell cycle g1 s phase transitionGO:0044843570.018
cell type specific apoptotic processGO:00972852680.018
positive regulation of nervous system developmentGO:00519622210.018
dna replicationGO:0006260520.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
fertilizationGO:00095661270.017
negative regulation of phosphorylationGO:00423261660.017
intracellular protein transportGO:00068862040.017
mitotic sister chromatid cohesionGO:000706410.017
response to organonitrogen compoundGO:00102432460.017
positive regulation of cell cycleGO:0045787920.017
regulation of lymphocyte activationGO:00512492400.017
regulation of cell divisionGO:0051302760.017
regulation of cytoplasmic transportGO:19036491120.017
protein localization to chromosome centromeric regionGO:007145910.017
establishment of organelle localizationGO:00516561220.016
response to inorganic substanceGO:0010035960.016
mitotic sister chromatid segregationGO:0000070140.016
ion transmembrane transportGO:00342203610.016
positive regulation of nuclear divisionGO:0051785270.016
dendrite developmentGO:00163581150.016
regulation of mapk cascadeGO:00434082480.016
regulation of cellular response to stressGO:00801351590.016
asymmetric neuroblast divisionGO:005505910.016
regulation of cytoskeleton organizationGO:00514931220.016
endomembrane system organizationGO:00102561470.016
microtubule based processGO:00070172360.016
nucleotide catabolic processGO:00091662170.016
circulatory system processGO:00030131970.016
regulation of cell motilityGO:20001452360.016
regulation of synaptic plasticityGO:0048167870.015
positive regulation of cell developmentGO:00107202370.015
nucleoside monophosphate metabolic processGO:0009123850.015
stem cell differentiationGO:00488632680.015
multicellular organismal homeostasisGO:00488711640.015
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.015
regulation of microtubule cytoskeleton organizationGO:0070507370.015
purine nucleoside metabolic processGO:00422782410.015
cellular lipid metabolic processGO:00442553230.015
negative regulation of cellular component organizationGO:00511291940.015
purine ribonucleoside monophosphate catabolic processGO:0009169570.015
muscle tissue developmentGO:00605373080.015
ras protein signal transductionGO:0007265770.015
cellular protein complex assemblyGO:00436231160.015
positive regulation of mitosisGO:0045840140.015
posttranscriptional regulation of gene expressionGO:00106081550.014
myeloid cell differentiationGO:00300992330.014
negative regulation of organelle organizationGO:0010639900.014
ribonucleoside monophosphate metabolic processGO:0009161800.014
forebrain developmentGO:00309003020.014
response to radiationGO:00093141650.014
atp catabolic processGO:0006200550.014
rhythmic processGO:00485111740.014
chromosome movement towards spindle poleGO:005130530.014
ribonucleotide catabolic processGO:00092612080.014
chromosome organization involved in meiosisGO:0070192390.014
glycosyl compound catabolic processGO:19016582060.014
apoptotic signaling pathwayGO:00971903060.014
regulation of hydrolase activityGO:00513362460.014
meiosis iiGO:000713570.014
regulation of protein catabolic processGO:00421761080.014
regulation of defense responseGO:00313472330.014
hematopoietic progenitor cell differentiationGO:00022441430.014
glycosyl compound metabolic processGO:19016572460.014
negative regulation of cellular amino acid metabolic processGO:004576300.013
blood circulationGO:00080151950.013
female meiotic divisionGO:0007143210.013
regulation of chromosome segregationGO:0051983210.013
carbohydrate metabolic processGO:00059752300.013
regulation of protein localizationGO:00328802310.013
inflammatory responseGO:00069542440.013
spindle assemblyGO:0051225130.013
t cell activationGO:00421102890.013
spindle assembly involved in female meiosisGO:000705630.013
cytoplasmic transportGO:00164822340.013
microtubule cytoskeleton organizationGO:00002261570.013
nucleoside monophosphate catabolic processGO:0009125590.013
negative regulation of cell developmentGO:00107211690.013
ossificationGO:00015032160.013
regulation of hormone levelsGO:00108172110.013
rho protein signal transductionGO:0007266320.013
positive regulation of exit from mitosisGO:003153610.013
positive regulation of mitotic cell cycleGO:0045931410.013
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.013
response to oxidative stressGO:00069791230.013
homeostasis of number of cellsGO:00488722100.013
purine nucleoside monophosphate catabolic processGO:0009128580.013
regulation of protein serine threonine kinase activityGO:00719001570.012
germ cell developmentGO:00072811850.012
positive regulation of protein catabolic processGO:0045732600.012
microtubule depolymerizationGO:0007019150.012
negative regulation of protein maturationGO:1903318790.012
cytokine productionGO:00018163190.012
stem cell proliferationGO:00720891170.012
positive regulation of cell deathGO:00109422240.012
regulation of nucleotide catabolic processGO:00308111220.012
cation transmembrane transportGO:00986552660.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
regulation of spindle organizationGO:009022420.012
negative regulation of cellular amine metabolic processGO:003323910.012
positive regulation of programmed cell deathGO:00430682180.012
membrane organizationGO:00610242450.012
regulation of bindingGO:00510981110.012
negative regulation of immune system processGO:00026832090.012
atp metabolic processGO:0046034750.012
chromatin disassemblyGO:003149810.012
dna endoreduplicationGO:004202340.012
regulation of mitotic sister chromatid segregationGO:0033047120.012
nuclear dna replicationGO:003326030.012
cytokinetic processGO:003250620.012
locomotory behaviorGO:00076261950.012
immune effector processGO:00022523210.011
divalent metal ion transportGO:00708381720.011
regulation of cell cycle phase transitionGO:1901987770.011
cellular response to cytokine stimulusGO:00713451890.011
cell adhesionGO:00071553290.011
inorganic ion transmembrane transportGO:00986602340.011
striated muscle tissue developmentGO:00147062930.011
guanosine containing compound catabolic processGO:19010691440.011
chromatin silencingGO:0006342150.011
spindle assembly involved in meiosisGO:009030640.011
cellular component assembly involved in morphogenesisGO:00109271390.011
innate immune responseGO:00450871570.011
regulation of proteasomal protein catabolic processGO:0061136460.011
response to light stimulusGO:00094161350.011
regulation of microtubule based processGO:0032886520.011
cellular chemical homeostasisGO:00550822150.011
regulation of protein modification by small protein conjugation or removalGO:1903320570.011
monocarboxylic acid metabolic processGO:00327871910.011
inorganic cation transmembrane transportGO:00986622070.011
regulation of inflammatory responseGO:00507271470.011
regulation of cellular protein catabolic processGO:1903362610.011
cellularizationGO:000734910.011
negative regulation of microtubule polymerizationGO:003111520.011
hatchingGO:003518840.011
oxidation reduction processGO:00551143420.011
sister chromatid cohesionGO:0007062120.011
stem cell developmentGO:00488642190.011
dephosphorylationGO:00163111290.011
positive regulation of cell cycle processGO:0090068610.011
regulation of establishment of protein localizationGO:00702011810.011
organic hydroxy compound metabolic processGO:19016152030.011
protein targetingGO:00066051430.011
regulation of anatomical structure sizeGO:00900661780.011
negative regulation of protein phosphorylationGO:00019331260.011
peptide hormone secretionGO:00300721090.011
microtubule polymerizationGO:0046785120.011
amide transportGO:00428861380.011
b cell activationGO:00421131610.011
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.011
regulation of cell activationGO:00508652890.010
muscle cell differentiationGO:00426922610.010
modification dependent macromolecule catabolic processGO:00436321330.010
cell maturationGO:00484691270.010
actin cytoskeleton organizationGO:00300362200.010
regulation of purine nucleotide metabolic processGO:19005421690.010
tube closureGO:0060606910.010
developmental maturationGO:00217001930.010
adaptive immune responseGO:00022501550.010
blood vessel morphogenesisGO:00485142850.010
lipid biosynthetic processGO:00086101790.010
translesion synthesisGO:001998510.010
response to organic cyclic compoundGO:00140701980.010
hormone secretionGO:00468791280.010
rna processingGO:00063961050.010
carbohydrate homeostasisGO:00335001280.010
gtp metabolic processGO:00460391440.010
signal transduction by p53 class mediatorGO:0072331510.010
leukocyte mediated immunityGO:00024431740.010
divalent inorganic cation transportGO:00725111780.010

Espl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.043
disease of cellular proliferationDOID:1456600.043
cancerDOID:16200.043
gastrointestinal system cancerDOID:311900.036
intestinal cancerDOID:1015500.024
large intestine cancerDOID:567200.024
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.016
disease of metabolismDOID:001466700.010
inherited metabolic disorderDOID:65500.010
colorectal cancerDOID:925600.010