Mus musculus

2 known processes

Nat2

N-acetyltransferase 2 (arylamine N-acetyltransferase)

(Aliases: AV377607)

Nat2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.101
negative regulation of molecular functionGO:00440922580.087
organic cyclic compound catabolic processGO:19013612950.072
nucleoside phosphate metabolic processGO:00067533380.070
cellular response to lipidGO:00713961450.070
cellular response to dna damage stimulusGO:00069742070.064
regulation of defense responseGO:00313472330.064
i kappab kinase nf kappab signalingGO:0007249850.059
organonitrogen compound biosynthetic processGO:19015661920.056
oxidation reduction processGO:00551143420.054
regulation of protein localizationGO:00328802310.053
cellular nitrogen compound catabolic processGO:00442702800.053
regulation of transferase activityGO:00513382630.052
regulation of protein transportGO:00512231630.051
aromatic compound catabolic processGO:00194392860.049
regulation of interleukin 1 alpha productionGO:003265040.049
organophosphate catabolic processGO:00464342320.047
positive regulation of secretionGO:00510471300.047
negative regulation of immune system processGO:00026832090.047
cytokine productionGO:00018163190.047
leukocyte mediated immunityGO:00024431740.046
response to molecule of bacterial originGO:00022371430.046
regulation of secretion by cellGO:19035302490.045
leukocyte differentiationGO:00025213420.044
b cell activationGO:00421131610.043
innate immune responseGO:00450871570.043
male gamete generationGO:00482322850.043
glycosyl compound metabolic processGO:19016572460.043
regulation of cell cycleGO:00517262810.043
nucleobase containing small molecule metabolic processGO:00550863520.043
organic hydroxy compound metabolic processGO:19016152030.043
cellular lipid metabolic processGO:00442553230.042
modification dependent macromolecule catabolic processGO:00436321330.042
regulation of lymphocyte activationGO:00512492400.041
myeloid cell differentiationGO:00300992330.040
sensory perceptionGO:00076002450.040
nucleotide metabolic processGO:00091173320.040
proteolysis involved in cellular protein catabolic processGO:00516031470.040
apoptotic signaling pathwayGO:00971903060.039
positive regulation of protein modification processGO:00314012990.038
cellular amine metabolic processGO:0044106440.038
nucleoside phosphate catabolic processGO:19012922220.038
ribonucleoside metabolic processGO:00091192450.037
regulation of secretionGO:00510462740.037
regulation of apoptotic signaling pathwayGO:20012331970.037
lipid biosynthetic processGO:00086101790.037
homeostasis of number of cellsGO:00488722100.037
regulation of cellular ketone metabolic processGO:0010565660.037
regulation of peptidase activityGO:0052547960.036
regulation of cellular amino acid metabolic processGO:000652150.036
spermatogenesisGO:00072832840.036
regulation of cellular component biogenesisGO:00440871810.036
cellular chemical homeostasisGO:00550822150.035
negative regulation of cellular protein metabolic processGO:00322692470.035
macromolecule catabolic processGO:00090572810.034
amine metabolic processGO:0009308450.034
regulation of cellular catabolic processGO:00313292420.034
cellular ketone metabolic processGO:0042180840.034
regulation of cell activationGO:00508652890.034
spermatid differentiationGO:00485151150.034
positive regulation of interleukin 1 alpha secretionGO:005071730.033
negative regulation of phosphate metabolic processGO:00459361840.033
cellular amino acid metabolic processGO:00065201030.033
apoptotic mitochondrial changesGO:0008637480.032
ribonucleotide metabolic processGO:00092592910.032
regulation of organelle organizationGO:00330432890.031
carbohydrate derivative catabolic processGO:19011362310.031
positive regulation of hydrolase activityGO:00513451480.031
cellular homeostasisGO:00197252400.031
nucleoside catabolic processGO:00091642060.031
cellular macromolecule catabolic processGO:00442652060.031
signal transduction in absence of ligandGO:0038034550.031
regulation of protein kinase activityGO:00458592320.030
nucleoside metabolic processGO:00091162460.030
negative regulation of cellular component organizationGO:00511291940.030
regulation of response to woundingGO:19030341890.030
regulation of kinase activityGO:00435492490.029
regulation of establishment of protein localizationGO:00702011810.029
positive regulation of secretion by cellGO:19035321140.029
glycosyl compound catabolic processGO:19016582060.029
response to oxidative stressGO:00069791230.029
t cell activationGO:00421102890.029
response to lipopolysaccharideGO:00324961280.029
ribose phosphate metabolic processGO:00196932910.028
response to topologically incorrect proteinGO:0035966250.028
retrograde transport endosome to golgiGO:004214720.028
autophagyGO:0006914450.028
purine ribonucleotide catabolic processGO:00091542080.028
defense response to other organismGO:00985421970.028
regulation of cytokine productionGO:00018172660.028
monocarboxylic acid metabolic processGO:00327871910.028
regulation of proteolysisGO:00301621640.028
interleukin 1 alpha secretionGO:005070330.028
regulation of hydrolase activityGO:00513362460.028
regulation of protein serine threonine kinase activityGO:00719001570.028
response to organonitrogen compoundGO:00102432460.027
lymphocyte differentiationGO:00300982420.027
negative regulation of intracellular signal transductionGO:19025321670.027
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.027
nitrogen compound transportGO:00717052710.027
Mouse
negative regulation of cell proliferationGO:00082852960.027
membrane organizationGO:00610242450.027
inflammatory responseGO:00069542440.027
activation of immune responseGO:00022531380.027
regulation of membrane potentialGO:00423911920.026
nucleotide catabolic processGO:00091662170.026
positive regulation of apoptotic processGO:00430652170.026
purine nucleoside metabolic processGO:00422782410.026
regulation of homeostatic processGO:00328441820.026
negative regulation of necroptotic processGO:006054690.026
ion transmembrane transportGO:00342203610.026
Mouse
positive regulation of cellular amine metabolic processGO:003324050.025
sphingolipid biosynthetic processGO:0030148260.025
purine containing compound metabolic processGO:00725213110.025
response to unfolded proteinGO:0006986210.025
protein catabolic processGO:00301632210.025
positive regulation of protein phosphorylationGO:00019342420.025
regulation of cellular amine metabolic processGO:0033238200.025
negative regulation of cell activationGO:00508661110.025
positive regulation of cell deathGO:00109422240.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
regulation of t cell activationGO:00508631700.024
positive regulation of innate immune responseGO:0045089800.024
membrane lipid biosynthetic processGO:0046467320.024
regulation of mapk cascadeGO:00434082480.024
mapk cascadeGO:00001652810.024
g protein coupled receptor signaling pathwayGO:00071862430.024
regulation of b cell activationGO:0050864810.024
positive regulation of interleukin 1 alpha productionGO:003273040.024
modification dependent protein catabolic processGO:00199411330.023
cation transportGO:00068123990.023
regulation of interleukin 1 alpha secretionGO:005070530.023
cell type specific apoptotic processGO:00972852680.023
protein maturationGO:00516041760.023
cytoplasmic transportGO:00164822340.023
sequestering of metal ionGO:0051238190.023
purine ribonucleoside metabolic processGO:00461282410.023
cellular response to oxidative stressGO:0034599760.022
protein processingGO:00164851630.022
sequestering of calcium ionGO:0051208180.022
vesicle organizationGO:0016050600.022
cellular response to hormone stimulusGO:00328701500.022
positive regulation of kinase activityGO:00336741550.022
cellular protein complex assemblyGO:00436231160.022
b cell proliferationGO:0042100530.022
negative regulation of apoptotic signaling pathwayGO:20012341040.022
carbohydrate derivative biosynthetic processGO:19011371830.022
maintenance of locationGO:0051235890.022
ribonucleotide catabolic processGO:00092612080.022
epithelial cell proliferationGO:00506731740.022
heterocycle catabolic processGO:00467002800.021
regulation of lipid metabolic processGO:00192161180.021
positive regulation of transferase activityGO:00513471670.021
negative regulation of phosphorus metabolic processGO:00105631840.021
myeloid cell homeostasisGO:00022621140.021
positive regulation of defense responseGO:00313491240.021
gland developmentGO:00487323300.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
regulation of cellular response to stressGO:00801351590.021
regulation of inflammatory responseGO:00507271470.021
lymphocyte proliferationGO:00466511640.021
compound eye developmentGO:004874910.021
regulation of sphingolipid biosynthetic processGO:009015310.021
cellular response to organic cyclic compoundGO:0071407870.020
lymphocyte mediated immunityGO:00024491390.020
posttranscriptional regulation of gene expressionGO:00106081550.020
regulation of cell projection organizationGO:00313442060.020
purine ribonucleoside catabolic processGO:00461302050.020
sensory perception of mechanical stimulusGO:00509541070.020
nucleoside triphosphate metabolic processGO:00091412300.020
exocytosisGO:00068871210.020
peptide transportGO:00158331330.020
positive regulation of lymphocyte activationGO:00512511400.020
regulation of toll like receptor 4 signaling pathwayGO:003414340.020
regulation of interleukin 8 secretionGO:200048220.020
regulation of b cell proliferationGO:0030888390.020
germ cell developmentGO:00072811850.020
purine containing compound catabolic processGO:00725232130.020
negative regulation of transferase activityGO:0051348850.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
spermatid developmentGO:00072861080.020
purine nucleotide catabolic processGO:00061952110.020
cation homeostasisGO:00550802120.020
ribonucleoside catabolic processGO:00424542060.020
negative regulation of protein metabolic processGO:00512482820.020
skin developmentGO:00435882200.019
extrinsic apoptotic signaling pathwayGO:00971911260.019
interleukin 8 productionGO:003263740.019
regulation of interleukin 8 productionGO:003267730.019
reactive oxygen species metabolic processGO:0072593840.019
cellular response to steroid hormone stimulusGO:0071383330.019
detection of molecule of bacterial originGO:003249020.019
organic anion transportGO:00157111370.019
Mouse
amide transportGO:00428861380.019
negative regulation of b cell activationGO:0050869270.019
wound healingGO:00420601570.019
lipid catabolic processGO:0016042690.018
regulation of body fluid levelsGO:00508781620.018
cellular response to cytokine stimulusGO:00713451890.018
positive regulation of programmed cell deathGO:00430682180.018
purine ribonucleotide metabolic processGO:00091502900.018
myeloid leukocyte differentiationGO:00025731190.018
cd8 positive alpha beta t cell extravasationGO:003569730.018
synaptic transmissionGO:00072683290.018
response to acid chemicalGO:00011011110.018
mitochondrion organizationGO:00070051340.018
immune effector processGO:00022523210.018
protein secretionGO:00093061110.018
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.018
leukocyte proliferationGO:00706611720.018
regulation of reactive oxygen species metabolic processGO:2000377400.018
negative regulation of phosphorylationGO:00423261660.018
purine nucleotide metabolic processGO:00061633020.018
neural tube developmentGO:00219151600.018
ribonucleoside triphosphate catabolic processGO:00092031990.017
alcohol metabolic processGO:00060661160.017
developmental maturationGO:00217001930.017
positive regulation of protein transportGO:0051222930.017
protein oligomerizationGO:0051259670.017
response to organic cyclic compoundGO:00140701980.017
cellular protein catabolic processGO:00442571550.017
sphingolipid metabolic processGO:0006665450.017
protein modification by small protein conjugation or removalGO:00706472070.017
dna endoreduplicationGO:004202340.017
cellular metal ion homeostasisGO:00068751510.017
regulation of vesicle mediated transportGO:00606271390.017
divalent metal ion transportGO:00708381720.017
immune response regulating signaling pathwayGO:00027641250.017
erythrocyte differentiationGO:0030218880.017
blood vessel morphogenesisGO:00485142850.017
divalent inorganic cation transportGO:00725111780.017
respiratory tube developmentGO:00303231670.017
microtubule based processGO:00070172360.016
negative regulation of cell cycleGO:00457861230.016
negative regulation of lymphocyte activationGO:0051250910.016
cellular response to molecule of bacterial originGO:0071219830.016
protein autophosphorylationGO:0046777610.016
anion transportGO:00068201770.016
Mouse
carboxylic acid catabolic processGO:0046395510.016
methylationGO:00322591340.016
embryonic epithelial tube formationGO:00018381300.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
purine ribonucleoside monophosphate metabolic processGO:0009167800.016
positive regulation of t cell receptor signaling pathwayGO:005086240.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
regulation of hormone levelsGO:00108172110.016
glial cell apoptotic processGO:003434930.016
blood circulationGO:00080151950.016
steroid metabolic processGO:00082021190.016
negative regulation of kinase activityGO:0033673810.016
pyroptosisGO:007026980.016
small gtpase mediated signal transductionGO:0007264970.016
peptide secretionGO:00027901140.016
protein targetingGO:00066051430.016
purine nucleoside catabolic processGO:00061522050.016
regulation of lymphocyte proliferationGO:00506701170.015
positive regulation of proteolysisGO:0045862850.015
epithelial tube morphogenesisGO:00605623030.015
peroxisomal transportGO:004357440.015
positive regulation of immune effector processGO:00026991070.015
protein modification by small protein conjugationGO:00324461870.015
epidermis developmentGO:00085441870.015
gonad developmentGO:00084061410.015
carbohydrate metabolic processGO:00059752300.015
regulation of cytokine secretionGO:0050707610.015
protein localization to nucleusGO:00345041210.015
intracellular protein transportGO:00068862040.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
regulation of neuron differentiationGO:00456642810.015
anatomical structure homeostasisGO:00602491450.015
neural tube formationGO:00018411080.015
positive regulation of cell activationGO:00508671580.015
adaptive immune responseGO:00022501550.015
hematopoietic progenitor cell differentiationGO:00022441430.015
peptidyl amino acid modificationGO:00181933360.014
morphogenesis of embryonic epitheliumGO:00163311590.014
meiotic cell cycle processGO:1903046770.014
transmembrane transportGO:00550854120.014
Mouse
lymphocyte homeostasisGO:0002260640.014
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.014
regulation of multi organism processGO:00439001110.014
organophosphate biosynthetic processGO:00904071220.014
cellular ion homeostasisGO:00068731650.014
negative regulation of interleukin 8 secretionGO:200048310.014
negative regulation of leukocyte proliferationGO:0070664460.014
response to oxygen levelsGO:0070482620.014
regulation of endopeptidase activityGO:0052548890.014
immune response activating signal transductionGO:00027571160.014
ubiquitin dependent protein catabolic processGO:00065111290.014
nucleoside triphosphate catabolic processGO:00091432050.014
wnt signaling pathwayGO:00160551880.014
positive regulation of nervous system developmentGO:00519622210.014
er nucleus signaling pathwayGO:0006984270.014
t cell proliferationGO:00420981200.014
regulation of protein catabolic processGO:00421761080.014
organonitrogen compound catabolic processGO:19015652640.014
respiratory system developmentGO:00605411900.013
regulation of protein secretionGO:0050708820.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
membrane depolarizationGO:0051899640.013
metal ion homeostasisGO:00550651890.013
coagulationGO:0050817780.013
positive regulation of cysteine type endopeptidase activityGO:2001056390.013
zymogen activationGO:0031638410.013
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.013
regulation of exocytosisGO:0017157610.013
lipid homeostasisGO:0055088630.013
positive regulation of mapk cascadeGO:00434101700.013
nucleic acid phosphodiester bond hydrolysisGO:0090305490.013
positive regulation of cellular catabolic processGO:00313311480.013
positive regulation of cell developmentGO:00107202370.013
protein localization to organelleGO:00333651850.013
microglial cell activationGO:000177430.013
protein importGO:00170381010.013
cellular response to lipopolysaccharideGO:0071222770.013
plasma cell differentiationGO:000231730.013
negative regulation of protein modification processGO:00314001630.013
muscle tissue developmentGO:00605373080.013
regulation of ion transportGO:00432692150.013
pattern recognition receptor signaling pathwayGO:0002221470.013
angiogenesisGO:00015252010.013
negative regulation of necrotic cell deathGO:0060547110.013
steroid biosynthetic processGO:0006694470.013
regulation of lipid biosynthetic processGO:0046890540.013
digestive system developmentGO:00551232000.013
carbohydrate homeostasisGO:00335001280.013
membrane fusionGO:0061025380.013
toll like receptor signaling pathwayGO:0002224380.013
cell maturationGO:00484691270.013
cellular response to acid chemicalGO:0071229680.013
small molecule catabolic processGO:0044282710.013
regulation of immunological synapse formationGO:200052020.012
positive regulation of leukocyte differentiationGO:1902107860.012
regulation of epithelial cell proliferationGO:00506781410.012
lipid transportGO:0006869980.012
glucose homeostasisGO:00425931280.012
regulation of leukocyte differentiationGO:19021051590.012
t cell differentiationGO:00302171740.012
ras protein signal transductionGO:0007265770.012
peptide hormone secretionGO:00300721090.012
negative regulation of t cell activationGO:0050868650.012
positive regulation of apoptotic signaling pathwayGO:2001235950.012
regulation of metal ion transportGO:00109591060.012
epithelial tube formationGO:00721751300.012
response to light stimulusGO:00094161350.012
calcium ion homeostasisGO:00550741270.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
tissue homeostasisGO:00018941150.012
rhythmic processGO:00485111740.012
defense response to bacteriumGO:00427421190.012
membrane hyperpolarizationGO:0060081210.012
regulation of leukocyte apoptotic processGO:2000106560.012
cell activation involved in immune responseGO:00022631260.012
response to nutrient levelsGO:00316671090.012
activation of cysteine type endopeptidase activityGO:0097202270.012
small molecule biosynthetic processGO:00442831320.012
asymmetric stem cell divisionGO:009872230.012
positive regulation of growthGO:00459271040.012
regulation of neuron deathGO:19012141340.012
transmission of nerve impulseGO:0019226760.012
mrna metabolic processGO:0016071840.012
calcium ion transportGO:00068161590.012
cytokine secretionGO:0050663720.012
release of cytochrome c from mitochondriaGO:0001836230.012
immune response regulating cell surface receptor signaling pathwayGO:0002768800.012
cation transmembrane transportGO:00986552660.012
neuron apoptotic processGO:00514021420.012
cellular calcium ion homeostasisGO:00068741190.012
inorganic cation transmembrane transportGO:00986622070.012
regulation of complement activation classical pathwayGO:003045010.011
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.011
morphogenesis of a branching epitheliumGO:00611381930.011
hemostasisGO:0007599780.011
extracellular structure organizationGO:00430621480.011
regulation of leukocyte proliferationGO:00706631210.011
oocyte constructionGO:000730820.011
muscle cell differentiationGO:00426922610.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
regulation of intracellular transportGO:00323861590.011
guanosine containing compound metabolic processGO:19010681440.011
regulation of innate immune responseGO:0045088910.011
cellular response to topologically incorrect proteinGO:0035967250.011
lung developmentGO:00303241640.011
hormone secretionGO:00468791280.011
extracellular matrix organizationGO:00301981470.011
viral life cycleGO:0019058360.011
alcohol biosynthetic processGO:0046165430.011
regulation of system processGO:00440572000.011
ossificationGO:00015032160.011
interleukin 8 secretionGO:007260630.011
tube formationGO:00351481400.011
leukocyte homeostasisGO:0001776790.011
gtp metabolic processGO:00460391440.011
organelle localizationGO:00516401790.011
ribonucleotide biosynthetic processGO:0009260590.011
nucleocytoplasmic transportGO:00069131390.011
establishment of protein localization to peroxisomeGO:007266340.011
symbiosis encompassing mutualism through parasitismGO:0044403830.011
regulation of t cell proliferationGO:0042129920.011
negative regulation of t cell proliferationGO:0042130380.011
heart contractionGO:0060047930.011
morphogenesis of a branching structureGO:00017632030.011
plasma membrane organizationGO:0007009900.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
regulation of myeloid cell differentiationGO:0045637960.011
regulation of protein complex assemblyGO:0043254830.011
striated muscle tissue developmentGO:00147062930.011
tissue remodelingGO:00487711020.011
sensory perception of soundGO:0007605970.010
dna catabolic process endonucleolyticGO:0000737150.010
regulation of bindingGO:00510981110.010
innate immune response activating signal transductionGO:0002758500.010
immune response activating cell surface receptor signaling pathwayGO:0002429720.010
hepatocyte apoptotic processGO:0097284110.010
multicellular organismal signalingGO:0035637910.010
nucleoside phosphate biosynthetic processGO:1901293790.010
cell fate commitmentGO:00451652100.010
oocyte axis specificationGO:000730920.010
negative regulation of protein phosphorylationGO:00019331260.010
fatty acid metabolic processGO:00066311210.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.010
negative regulation of b cell proliferationGO:0030889130.010
positive regulation of protein oligomerizationGO:003246140.010
cell killingGO:0001906670.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.010
ceramide metabolic processGO:0006672310.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
protein import into nucleusGO:0006606950.010
positive regulation of cytokine productionGO:00018191740.010

Nat2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.026
disease of cellular proliferationDOID:1456600.022
disease of metabolismDOID:001466700.019
cancerDOID:16200.019
thoracic cancerDOID:509300.014
organ system cancerDOID:005068600.014
inherited metabolic disorderDOID:65500.011
eye diseaseDOID:561400.010
sensory system diseaseDOID:005015500.010
eye and adnexa diseaseDOID:149200.010