Mus musculus

0 known processes

Tspan4

tetraspanin 4

(Aliases: AI325509,Tspan-4,NAG-2,Tm4sf7,MGC102386,AI746565,D130042I01Rik)

Tspan4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.128
amine metabolic processGO:0009308450.123
ion transmembrane transportGO:00342203610.117
positive regulation of cellular amine metabolic processGO:003324050.116
transmembrane transportGO:00550854120.107
regulation of cellular amino acid metabolic processGO:000652150.105
regulation of cellular amine metabolic processGO:0033238200.102
cellular amine metabolic processGO:0044106440.095
cellular ketone metabolic processGO:0042180840.089
mapk cascadeGO:00001652810.087
oxidation reduction processGO:00551143420.087
negative regulation of molecular functionGO:00440922580.079
immune effector processGO:00022523210.078
regulation of cellular ketone metabolic processGO:0010565660.075
positive regulation of cellular amino acid metabolic processGO:004576430.074
regulation of mapk cascadeGO:00434082480.070
nucleotide metabolic processGO:00091173320.069
regulation of apoptotic signaling pathwayGO:20012331970.067
hexose metabolic processGO:0019318980.067
apoptotic signaling pathwayGO:00971903060.063
membrane organizationGO:00610242450.063
inflammatory responseGO:00069542440.058
circulatory system processGO:00030131970.058
organic hydroxy compound metabolic processGO:19016152030.057
positive regulation of protein phosphorylationGO:00019342420.057
nitrogen compound transportGO:00717052710.056
regulation of defense responseGO:00313472330.054
nucleobase containing small molecule metabolic processGO:00550863520.054
negative regulation of cellular protein metabolic processGO:00322692470.054
striated muscle tissue developmentGO:00147062930.052
monocarboxylic acid metabolic processGO:00327871910.051
cellular lipid metabolic processGO:00442553230.049
urogenital system developmentGO:00016552610.048
regulation of response to woundingGO:19030341890.048
purine nucleoside catabolic processGO:00061522050.047
leukocyte differentiationGO:00025213420.043
response to lipopolysaccharideGO:00324961280.042
cell substrate adhesionGO:00315891300.042
organonitrogen compound catabolic processGO:19015652640.042
regulation of ossificationGO:00302781120.041
nucleoside phosphate metabolic processGO:00067533380.041
anion transportGO:00068201770.041
cation transportGO:00068123990.041
leukocyte mediated immunityGO:00024431740.041
cellular response to molecule of bacterial originGO:0071219830.041
negative regulation of protein metabolic processGO:00512482820.040
positive regulation of protein modification processGO:00314012990.040
regulation of cell motilityGO:20001452360.039
lipid biosynthetic processGO:00086101790.039
carbohydrate metabolic processGO:00059752300.039
negative regulation of phosphorus metabolic processGO:00105631840.039
negative regulation of phosphorylationGO:00423261660.038
extracellular matrix organizationGO:00301981470.037
fat cell differentiationGO:00454441600.037
cell adhesionGO:00071553290.037
blood circulationGO:00080151950.037
myeloid cell differentiationGO:00300992330.037
regulation of protein kinase activityGO:00458592320.036
regulation of blood pressureGO:0008217930.036
lateral inhibitionGO:004633110.036
monosaccharide metabolic processGO:00059961060.036
response to nutrient levelsGO:00316671090.035
regulation of membrane potentialGO:00423911920.035
innate immune responseGO:00450871570.035
cellular modified amino acid metabolic processGO:0006575630.035
purine containing compound metabolic processGO:00725213110.034
activation of immune responseGO:00022531380.034
ossificationGO:00015032160.034
regulation of hydrolase activityGO:00513362460.034
regulation of protein processingGO:0070613960.034
aromatic compound catabolic processGO:00194392860.034
regulation of peptidase activityGO:0052547960.033
cation transmembrane transportGO:00986552660.032
glycerolipid metabolic processGO:00464861220.032
positive regulation of mapk cascadeGO:00434101700.031
purine ribonucleoside metabolic processGO:00461282410.031
negative regulation of phosphate metabolic processGO:00459361840.031
purine containing compound catabolic processGO:00725232130.031
intracellular protein transportGO:00068862040.030
male gamete generationGO:00482322850.030
regulation of protein localizationGO:00328802310.030
regulation of cell migrationGO:00303342190.030
immune response activating signal transductionGO:00027571160.030
carbohydrate derivative catabolic processGO:19011362310.029
cellular chemical homeostasisGO:00550822150.029
heterocycle catabolic processGO:00467002800.029
response to insulinGO:00328681000.029
reactive oxygen species metabolic processGO:0072593840.029
small molecule biosynthetic processGO:00442831320.028
cellular carbohydrate metabolic processGO:00442621190.028
nucleoside triphosphate metabolic processGO:00091412300.028
dna metabolic processGO:00062593030.028
angiogenesisGO:00015252010.028
purine ribonucleotide metabolic processGO:00091502900.028
cellular homeostasisGO:00197252400.028
nucleoside phosphate catabolic processGO:19012922220.028
regulation of intracellular transportGO:00323861590.028
peptidyl amino acid modificationGO:00181933360.028
glycosyl compound metabolic processGO:19016572460.028
organic cyclic compound catabolic processGO:19013612950.028
purine ribonucleotide catabolic processGO:00091542080.027
entry into cell of other organism involved in symbiotic interactionGO:0051806150.027
defense response to other organismGO:00985421970.027
inorganic ion transmembrane transportGO:00986602340.027
negative regulation of cell proliferationGO:00082852960.027
purine nucleoside triphosphate metabolic processGO:00091442260.026
positive regulation of secretionGO:00510471300.026
regulation of proteolysisGO:00301621640.026
cellular response to cytokine stimulusGO:00713451890.026
alcohol metabolic processGO:00060661160.026
cellular nitrogen compound catabolic processGO:00442702800.026
negative regulation of protein phosphorylationGO:00019331260.026
organic anion transportGO:00157111370.026
nucleoside metabolic processGO:00091162460.026
glycerophospholipid metabolic processGO:0006650710.025
gland developmentGO:00487323300.025
ribonucleoside catabolic processGO:00424542060.025
synaptic transmissionGO:00072683290.025
immune response regulating signaling pathwayGO:00027641250.024
carboxylic acid transportGO:00469421000.024
purine nucleoside metabolic processGO:00422782410.024
response to oxidative stressGO:00069791230.024
positive regulation of cell deathGO:00109422240.024
protein maturationGO:00516041760.024
divalent metal ion transportGO:00708381720.024
purine ribonucleoside catabolic processGO:00461302050.024
regulation of organelle organizationGO:00330432890.024
response to extracellular stimulusGO:00099911270.023
guanosine containing compound metabolic processGO:19010681440.023
response to organonitrogen compoundGO:00102432460.023
negative regulation of protein modification processGO:00314001630.023
extracellular structure organizationGO:00430621480.023
regulation of transferase activityGO:00513382630.023
glycerolipid biosynthetic processGO:0045017500.023
positive regulation of protein kinase activityGO:00458601440.023
cytoplasmic transportGO:00164822340.023
carbohydrate derivative biosynthetic processGO:19011371830.022
regulation of innate immune responseGO:0045088910.022
small molecule catabolic processGO:0044282710.022
posttranscriptional regulation of gene expressionGO:00106081550.022
regulation of osteoblast differentiationGO:0045667670.022
glucose metabolic processGO:0006006920.022
regulation of endocytosisGO:0030100690.022
lung developmentGO:00303241640.022
cellular response to lipopolysaccharideGO:0071222770.022
regulation of cell activationGO:00508652890.022
endocytosisGO:00068971680.022
ribonucleoside metabolic processGO:00091192450.022
regulation of secretion by cellGO:19035302490.022
regulation of ion transportGO:00432692150.022
regulation of anatomical structure sizeGO:00900661780.021
establishment of protein localization to organelleGO:00725941180.021
mitochondrion organizationGO:00070051340.021
glucose homeostasisGO:00425931280.021
positive regulation of defense responseGO:00313491240.021
organophosphate catabolic processGO:00464342320.021
endomembrane system organizationGO:00102561470.021
carbohydrate homeostasisGO:00335001280.021
regulation of lymphocyte activationGO:00512492400.021
cell matrix adhesionGO:0007160680.021
ribonucleoside triphosphate catabolic processGO:00092031990.021
organonitrogen compound biosynthetic processGO:19015661920.020
regulation of hormone levelsGO:00108172110.020
epithelial tube morphogenesisGO:00605623030.020
protein localization to membraneGO:00726571080.020
cellular response to organonitrogen compoundGO:00714171450.020
ribonucleoside triphosphate metabolic processGO:00091992200.020
anion transmembrane transportGO:0098656710.020
positive regulation of response to woundingGO:1903036660.020
negative regulation of defense responseGO:0031348770.020
divalent inorganic cation transportGO:00725111780.019
leukocyte proliferationGO:00706611720.019
positive regulation of apoptotic processGO:00430652170.019
entry into host cellGO:0030260150.019
negative regulation of multi organism processGO:0043901680.019
sulfur compound metabolic processGO:00067901000.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
epithelial cell proliferationGO:00506731740.019
lymphocyte mediated immunityGO:00024491390.019
regulation of cytoplasmic transportGO:19036491120.019
cell type specific apoptotic processGO:00972852680.019
regulation of multi organism processGO:00439001110.019
negative regulation of transferase activityGO:0051348850.019
cellular response to hormone stimulusGO:00328701500.019
cation homeostasisGO:00550802120.019
regulation of protein transportGO:00512231630.019
macromolecule catabolic processGO:00090572810.018
skeletal muscle organ developmentGO:00605381630.018
organic acid biosynthetic processGO:0016053860.018
inorganic cation transmembrane transportGO:00986622070.018
muscle cell differentiationGO:00426922610.018
Mouse
regulation of purine nucleotide metabolic processGO:19005421690.018
wound healingGO:00420601570.018
regulation of nucleotide metabolic processGO:00061401690.018
protein processingGO:00164851630.018
phospholipid metabolic processGO:0006644870.018
regulation of cell adhesionGO:00301551540.018
carboxylic acid biosynthetic processGO:0046394860.018
purine ribonucleoside triphosphate metabolic processGO:00092052200.018
regulation of lipid metabolic processGO:00192161180.018
action potentialGO:0001508780.018
negative regulation of cellular component organizationGO:00511291940.018
nucleocytoplasmic transportGO:00069131390.018
cellular response to lipidGO:00713961450.018
single organism nuclear importGO:1902593950.018
positive regulation of programmed cell deathGO:00430682180.018
organic acid transportGO:00158491010.018
lymphocyte proliferationGO:00466511640.017
nucleotide catabolic processGO:00091662170.017
glycoprotein biosynthetic processGO:0009101890.017
cell activation involved in immune responseGO:00022631260.017
glycoprotein metabolic processGO:00091001160.017
respiratory system developmentGO:00605411900.017
cytokine productionGO:00018163190.017
regulation of secretionGO:00510462740.017
protein secretionGO:00093061110.017
regulation of cytokine productionGO:00018172660.017
guanosine containing compound catabolic processGO:19010691440.017
regulation of fat cell differentiationGO:0045598810.017
respiratory tube developmentGO:00303231670.017
chemotaxisGO:00069352470.017
negative regulation of cellular amine metabolic processGO:003323910.017
wnt signaling pathwayGO:00160551880.017
nucleoside catabolic processGO:00091642060.017
epithelial cell developmentGO:00020641590.017
sensory perceptionGO:00076002450.016
cellular response to peptide hormone stimulusGO:0071375920.016
renal system developmentGO:00720012250.016
regulation of system processGO:00440572000.016
calcium ion transportGO:00068161590.016
organophosphate biosynthetic processGO:00904071220.016
regulation of transmembrane transportGO:00347621280.016
negative regulation of ossificationGO:0030279490.016
protein localization to organelleGO:00333651850.016
kidney developmentGO:00018222130.016
cytokine mediated signaling pathwayGO:00192211150.016
ribose phosphate metabolic processGO:00196932910.016
response to monosaccharideGO:0034284670.016
phagosome maturationGO:009038240.016
cellular response to peptideGO:1901653920.016
response to inorganic substanceGO:0010035960.016
purine nucleotide metabolic processGO:00061633020.016
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.016
regulation of systemic arterial blood pressureGO:0003073610.016
placenta developmentGO:00018901400.016
bone developmentGO:00603481200.016
i kappab kinase nf kappab signalingGO:0007249850.016
ribonucleotide metabolic processGO:00092592910.016
myeloid leukocyte differentiationGO:00025731190.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
negative regulation of intracellular signal transductionGO:19025321670.015
sterol metabolic processGO:0016125580.015
cellular response to carbohydrate stimulusGO:0071322500.015
interspecies interaction between organismsGO:0044419830.015
regulation of phosphatidylcholine catabolic processGO:001089920.015
brown fat cell differentiationGO:0050873360.015
regulation of neuron apoptotic processGO:00435231220.015
ribonucleotide biosynthetic processGO:0009260590.015
renal system processGO:0003014480.015
regulation of kinase activityGO:00435492490.015
regulation of leukocyte differentiationGO:19021051590.015
peptidyl tyrosine modificationGO:00182121450.015
regulation of epithelial cell proliferationGO:00506781410.015
regulation of inflammatory responseGO:00507271470.015
regulation of vesicle mediated transportGO:00606271390.015
positive regulation of apoptotic signaling pathwayGO:2001235950.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
positive regulation of map kinase activityGO:0043406840.015
metal ion homeostasisGO:00550651890.015
acetylcholine transportGO:001587020.015
reactive nitrogen species metabolic processGO:200105700.014
protein catabolic processGO:00301632210.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
response to acid chemicalGO:00011011110.014
t cell activationGO:00421102890.014
regulation of cellular catabolic processGO:00313292420.014
nuclear importGO:0051170950.014
regulation of glucose metabolic processGO:0010906600.014
cellular macromolecule catabolic processGO:00442652060.014
positive regulation of inflammatory responseGO:0050729470.014
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.014
embryonic organ morphogenesisGO:00485622760.014
response to growth factorGO:00708481980.014
rhythmic processGO:00485111740.014
l amino acid transportGO:0015807320.014
multicellular organism growthGO:00352641610.014
regulation of homeostatic processGO:00328441820.014
somite developmentGO:0061053810.014
positive regulation of kinase activityGO:00336741550.014
spermatogenesisGO:00072832840.014
response to molecule of bacterial originGO:00022371430.014
negative regulation of proteolysisGO:0045861740.014
sphingolipid metabolic processGO:0006665450.014
symbiosis encompassing mutualism through parasitismGO:0044403830.013
stress activated mapk cascadeGO:0051403800.013
positive regulation of endocytosisGO:0045807420.013
regulation of map kinase activityGO:00434051200.013
muscle tissue developmentGO:00605373080.013
cholesterol storageGO:001087840.013
response to peptideGO:19016521360.013
glycosyl compound catabolic processGO:19016582060.013
organic hydroxy compound transportGO:0015850930.013
positive regulation of transferase activityGO:00513471670.013
skeletal system developmentGO:00015013560.013
response to light stimulusGO:00094161350.013
peptide transportGO:00158331330.013
anatomical structure homeostasisGO:00602491450.013
adaptive immune responseGO:00022501550.013
hindbrain developmentGO:00309021280.013
t cell proliferationGO:00420981200.013
cellular biogenic amine metabolic processGO:0006576280.013
nuclear transportGO:00511691390.013
nephron epithelium developmentGO:0072009920.013
protein localization to vacuoleGO:007266540.013
response to organic cyclic compoundGO:00140701980.013
positive regulation of ossificationGO:0045778470.013
plasma lipoprotein particle clearanceGO:0034381130.013
neuron apoptotic processGO:00514021420.013
female meiosis chromosome segregationGO:001632110.012
amide transportGO:00428861380.012
morphogenesis of a branching epitheliumGO:00611381930.012
response to radiationGO:00093141650.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
negative regulation of cell motilityGO:2000146610.012
protein targetingGO:00066051430.012
leukocyte migrationGO:00509001240.012
regulation of protein targetingGO:1903533610.012
purine nucleotide biosynthetic processGO:0006164650.012
detection of molecule of bacterial originGO:003249020.012
regulation of monocyte chemotaxisGO:009002530.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
small gtpase mediated signal transductionGO:0007264970.012
response to oxygen radicalGO:0000305160.012
organelle fissionGO:00482851700.012
steroid metabolic processGO:00082021190.012
multi multicellular organism processGO:00447061090.012
positive regulation of nervous system developmentGO:00519622210.012
cholesterol catabolic processGO:000670750.012
canonical wnt signaling pathwayGO:00600701300.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
cellular response to extracellular stimulusGO:0031668810.012
positive regulation of cholesterol storageGO:001088630.012
regulation of angiogenesisGO:0045765810.012
regulation of establishment of protein localizationGO:00702011810.012
cofactor metabolic processGO:0051186800.012
gtp metabolic processGO:00460391440.012
carbohydrate biosynthetic processGO:0016051740.012
neuronal action potentialGO:0019228540.012
multicellular organismal homeostasisGO:00488711640.012
axonogenesisGO:00074092740.012
ribonucleotide catabolic processGO:00092612080.012
vascular process in circulatory systemGO:0003018620.012
negative regulation of immune system processGO:00026832090.012
response to reactive oxygen speciesGO:0000302560.012
neuron deathGO:00709971540.012
cellular response to dna damage stimulusGO:00069742070.012
development of primary sexual characteristicsGO:00451371430.012
negative regulation of neuron apoptotic processGO:0043524920.012
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.011
multicellular organismal signalingGO:0035637910.011
monosaccharide transportGO:0015749580.011
regulation of cellular carbohydrate metabolic processGO:0010675750.011
homeostasis of number of cellsGO:00488722100.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
negative regulation of growthGO:0045926990.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
regulation of ion transmembrane transportGO:00347651190.011
protein localization to plasma membraneGO:0072659570.011
sterol homeostasisGO:0055092450.011
negative regulation of cell activationGO:00508661110.011
male gonad developmentGO:0008584880.011
defense response to virusGO:0051607680.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
regulation of neuron deathGO:19012141340.011
rho protein signal transductionGO:0007266320.011
protein kinase b signalingGO:0043491740.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
peptide hormone secretionGO:00300721090.011
hormone metabolic processGO:0042445860.011
regulation of tube sizeGO:0035150570.011
circadian regulation of gene expressionGO:0032922480.011
sequestering of calcium ionGO:0051208180.011
regulation of immunological synapse formationGO:200052020.011
blood vessel morphogenesisGO:00485142850.011
positive regulation of apoptotic cell clearanceGO:200042730.011
activation of adenylate cyclase activityGO:000719040.011
regulation of protein maturationGO:1903317960.011
gonad developmentGO:00084061410.011
regulation of body fluid levelsGO:00508781620.011
hexose transportGO:0008645560.011
apoptotic mitochondrial changesGO:0008637480.011
heart contractionGO:0060047930.011
negative regulation of neuron deathGO:1901215980.011
regulation of cellular response to stressGO:00801351590.011
organic hydroxy compound catabolic processGO:1901616250.011
hemostasisGO:0007599780.011
response to peptide hormoneGO:00434341270.011
skeletal system morphogenesisGO:00487052030.010
regulation of nucleocytoplasmic transportGO:0046822730.010
positive regulation of cell migrationGO:00303351090.010
hormone secretionGO:00468791280.010
cellular response to inorganic substanceGO:0071241370.010
muscle system processGO:00030121410.010
nucleotide biosynthetic processGO:0009165780.010
lipid homeostasisGO:0055088630.010
cognitionGO:00508901490.010
nucleoside phosphate biosynthetic processGO:1901293790.010
positive regulation of cell developmentGO:00107202370.010
cellular glucose homeostasisGO:0001678520.010
hepaticobiliary system developmentGO:0061008670.010
purine nucleotide catabolic processGO:00061952110.010
regulation of carbohydrate metabolic processGO:0006109750.010
cellular response to biotic stimulusGO:0071216920.010
regulation of mitochondrion organizationGO:0010821270.010
regulation of erk1 and erk2 cascadeGO:0070372710.010
positive regulation of coagulationGO:0050820130.010
regulation of protein serine threonine kinase activityGO:00719001570.010
macromolecule glycosylationGO:0043413550.010
recognition of apoptotic cellGO:004365430.010
locomotory behaviorGO:00076261950.010
t cell mediated immunityGO:0002456500.010
regulation of removal of superoxide radicalsGO:200012140.010
glutathione metabolic processGO:0006749160.010

Tspan4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.041
inherited metabolic disorderDOID:65500.041
disease of anatomical entityDOID:700.035
connective tissue diseaseDOID:6500.035
musculoskeletal system diseaseDOID:1700.035
bone diseaseDOID:008000100.035
bone development diseaseDOID:008000600.030
immune system diseaseDOID:291400.020
osteochondrodysplasiaDOID:225600.016
nervous system diseaseDOID:86300.016
hematopoietic system diseaseDOID:7400.011