Mus musculus

0 known processes

Tspan8

tetraspanin 8

(Aliases: MGC38363,C76990,Tm4sf3,E330007O21Rik)

Tspan8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.239
ion transmembrane transportGO:00342203610.141
cellular amine metabolic processGO:0044106440.105
anion transportGO:00068201770.103
cation transportGO:00068123990.101
cellular ketone metabolic processGO:0042180840.077
amine metabolic processGO:0009308450.076
drug catabolic processGO:004273720.072
cation transmembrane transportGO:00986552660.071
cytokine productionGO:00018163190.071
cellular amino acid metabolic processGO:00065201030.068
immune effector processGO:00022523210.062
inorganic ion transmembrane transportGO:00986602340.056
t cell activationGO:00421102890.053
inorganic cation transmembrane transportGO:00986622070.050
regulation of cellular amino acid metabolic processGO:000652150.049
anion transmembrane transportGO:0098656710.047
cellular ion homeostasisGO:00068731650.045
cellular lipid metabolic processGO:00442553230.045
organic anion transportGO:00157111370.045
cellular homeostasisGO:00197252400.042
negative regulation of immune system processGO:00026832090.042
carbohydrate derivative biosynthetic processGO:19011371830.042
nucleotide metabolic processGO:00091173320.041
regulation of cellular amine metabolic processGO:0033238200.039
regulation of reactive oxygen species metabolic processGO:2000377400.038
carbohydrate metabolic processGO:00059752300.038
male gamete generationGO:00482322850.038
divalent inorganic cation transportGO:00725111780.036
action potentialGO:0001508780.036
Mouse
nitrogen compound transportGO:00717052710.036
regulation of cellular ketone metabolic processGO:0010565660.035
regulation of protein localizationGO:00328802310.034
divalent metal ion transportGO:00708381720.033
leukocyte mediated immunityGO:00024431740.033
purine containing compound metabolic processGO:00725213110.033
positive regulation of cellular amino acid metabolic processGO:004576430.032
inorganic anion transportGO:0015698430.032
drug metabolic processGO:001714440.032
nucleobase containing small molecule metabolic processGO:00550863520.032
leukocyte proliferationGO:00706611720.032
transepithelial chloride transportGO:003032140.031
cellular response to cytokine stimulusGO:00713451890.031
endomembrane system organizationGO:00102561470.031
regulation of ion transportGO:00432692150.031
glycoprotein metabolic processGO:00091001160.030
regulation of secretionGO:00510462740.030
cellular chemical homeostasisGO:00550822150.030
nucleoside phosphate metabolic processGO:00067533380.030
positive regulation of cellular amine metabolic processGO:003324050.030
regulation of cell activationGO:00508652890.030
membrane organizationGO:00610242450.030
regulation of cytokine productionGO:00018172660.029
regulation of lymphocyte activationGO:00512492400.029
protein processingGO:00164851630.029
negative regulation of phosphate metabolic processGO:00459361840.029
regulation of membrane potentialGO:00423911920.029
Mouse
protein maturationGO:00516041760.029
sensory perceptionGO:00076002450.029
purine ribonucleoside metabolic processGO:00461282410.029
leukocyte activation involved in immune responseGO:00023661260.028
glycosyl compound metabolic processGO:19016572460.028
monocarboxylic acid metabolic processGO:00327871910.028
transmission of nerve impulseGO:0019226760.028
Mouse
myeloid cell differentiationGO:00300992330.028
Mouse
regulation of t cell activationGO:00508631700.028
organic hydroxy compound metabolic processGO:19016152030.028
negative regulation of molecular functionGO:00440922580.028
circulatory system processGO:00030131970.028
apoptotic signaling pathwayGO:00971903060.028
spermatogenesisGO:00072832840.028
cell activation involved in immune responseGO:00022631260.027
cation homeostasisGO:00550802120.027
actin cytoskeleton organizationGO:00300362200.027
carboxylic acid transportGO:00469421000.027
respiratory system developmentGO:00605411900.027
cellular nitrogen compound catabolic processGO:00442702800.026
muscle system processGO:00030121410.026
regulation of organelle organizationGO:00330432890.026
metal ion homeostasisGO:00550651890.026
homeostasis of number of cellsGO:00488722100.026
glycoprotein biosynthetic processGO:0009101890.026
multicellular organismal signalingGO:0035637910.026
Mouse
inorganic anion transmembrane transportGO:0098661290.026
divalent inorganic cation homeostasisGO:00725071380.026
calcium ion homeostasisGO:00550741270.026
positive regulation of reactive oxygen species metabolic processGO:2000379110.025
regulation of homeostatic processGO:00328441820.025
regulation of multi organism processGO:00439001110.025
fertilizationGO:00095661270.025
innate immune responseGO:00450871570.025
response to molecule of bacterial originGO:00022371430.025
calcium ion transportGO:00068161590.025
regulation of hormone levelsGO:00108172110.025
cytokine mediated signaling pathwayGO:00192211150.025
norepinephrine transportGO:001587420.025
macromolecule glycosylationGO:0043413550.025
lipid localizationGO:00108761260.025
nucleoside metabolic processGO:00091162460.025
aromatic compound catabolic processGO:00194392860.025
cofactor metabolic processGO:0051186800.024
response to lipopolysaccharideGO:00324961280.024
lymphocyte proliferationGO:00466511640.024
regulation of cell motilityGO:20001452360.024
negative regulation of hydrolase activityGO:0051346710.024
purine nucleoside metabolic processGO:00422782410.024
regulation of anatomical structure sizeGO:00900661780.024
lipid biosynthetic processGO:00086101790.024
organonitrogen compound biosynthetic processGO:19015661920.023
regulation of body fluid levelsGO:00508781620.023
Rat
ribonucleotide metabolic processGO:00092592910.023
cellular metal ion homeostasisGO:00068751510.023
leukocyte mediated cytotoxicityGO:0001909620.023
amino acid transmembrane transportGO:0003333370.023
negative regulation of cellular amine metabolic processGO:003323910.023
cellular response to lipidGO:00713961450.023
locomotory behaviorGO:00076261950.022
defense response to bacteriumGO:00427421190.022
immune response activating signal transductionGO:00027571160.022
lymphocyte mediated immunityGO:00024491390.022
monovalent inorganic cation homeostasisGO:0055067330.022
wound healingGO:00420601570.022
Rat
negative regulation of cellular amino acid metabolic processGO:004576300.022
regulation of vesicle mediated transportGO:00606271390.022
response to organic cyclic compoundGO:00140701980.022
leukocyte differentiationGO:00025213420.022
Mouse
organonitrogen compound catabolic processGO:19015652640.022
negative regulation of phosphorus metabolic processGO:00105631840.022
negative regulation of protein metabolic processGO:00512482820.022
regulation of cell cycleGO:00517262810.022
reactive nitrogen species metabolic processGO:200105700.021
activation of immune responseGO:00022531380.021
organic cyclic compound catabolic processGO:19013612950.021
epithelial tube morphogenesisGO:00605623030.021
blood circulationGO:00080151950.021
reactive oxygen species biosynthetic processGO:190340980.021
lymphocyte differentiationGO:00300982420.021
negative regulation of growthGO:0045926990.021
purine nucleoside triphosphate metabolic processGO:00091442260.021
respiratory tube developmentGO:00303231670.021
regulation of establishment of protein localizationGO:00702011810.021
regulation of protein maturationGO:1903317960.021
regulation of innate immune responseGO:0045088910.021
organic acid transportGO:00158491010.021
nucleoside phosphate catabolic processGO:19012922220.020
oxidation reduction processGO:00551143420.020
protein ubiquitinationGO:00165671710.020
regulation of system processGO:00440572000.020
positive regulation of secretionGO:00510471300.020
t cell proliferationGO:00420981200.020
cell adhesionGO:00071553290.020
intracellular protein transportGO:00068862040.020
ribonucleoside triphosphate metabolic processGO:00091992200.019
ear developmentGO:00435832000.019
nucleoside triphosphate metabolic processGO:00091412300.019
ras protein signal transductionGO:0007265770.019
lung developmentGO:00303241640.019
protein glycosylationGO:0006486550.019
glycosyl compound catabolic processGO:19016582060.019
g protein coupled receptor signaling pathwayGO:00071862430.019
heterocycle catabolic processGO:00467002800.019
positive regulation of lymphocyte activationGO:00512511400.019
response to acid chemicalGO:00011011110.019
actin filament organizationGO:00070151130.019
regulation of hydrolase activityGO:00513362460.019
regulation of transferase activityGO:00513382630.019
macromolecule catabolic processGO:00090572810.019
organic hydroxy compound transportGO:0015850930.019
regulation of reactive oxygen species biosynthetic processGO:190342620.019
regulation of transmembrane transportGO:00347621280.018
negative regulation of cellular protein metabolic processGO:00322692470.018
cell type specific apoptotic processGO:00972852680.018
purine nucleotide metabolic processGO:00061633020.018
organophosphate catabolic processGO:00464342320.018
reactive oxygen species metabolic processGO:0072593840.018
regulation of epithelial cell proliferationGO:00506781410.018
regulation of cellular catabolic processGO:00313292420.018
cell substrate adhesionGO:00315891300.018
regulation of lymphocyte proliferationGO:00506701170.018
chemotaxisGO:00069352470.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
regulation of leukocyte proliferationGO:00706631210.018
positive regulation of defense responseGO:00313491240.018
protein modification by small protein conjugationGO:00324461870.018
ribonucleoside metabolic processGO:00091192450.018
sensory organ morphogenesisGO:00905962420.018
dna metabolic processGO:00062593030.018
small gtpase mediated signal transductionGO:0007264970.018
organophosphate biosynthetic processGO:00904071220.018
protein modification by small protein conjugation or removalGO:00706472070.017
positive regulation of protein phosphorylationGO:00019342420.017
posttranscriptional regulation of gene expressionGO:00106081550.017
angiogenesisGO:00015252010.017
ribonucleoside triphosphate catabolic processGO:00092031990.017
maintenance of locationGO:0051235890.017
regulation of secretion by cellGO:19035302490.017
regulation of protein processingGO:0070613960.017
alpha beta t cell activationGO:0046631910.017
negative regulation of cellular component organizationGO:00511291940.017
regulation of cellular component biogenesisGO:00440871810.017
kidney developmentGO:00018222130.017
cell killingGO:0001906670.016
glycosylationGO:0070085620.016
ribose phosphate metabolic processGO:00196932910.016
interspecies interaction between organismsGO:0044419830.016
hormone metabolic processGO:0042445860.016
response to drugGO:0042493750.016
nucleotide catabolic processGO:00091662170.016
cellular divalent inorganic cation homeostasisGO:00725031270.016
naphthalene containing compound metabolic processGO:009042010.016
alcohol metabolic processGO:00060661160.016
neuromuscular processGO:0050905990.016
endocytosisGO:00068971680.016
steroid metabolic processGO:00082021190.016
germ cell developmentGO:00072811850.016
negative regulation of protein maturationGO:1903318790.016
nucleoside catabolic processGO:00091642060.016
peptidyl amino acid modificationGO:00181933360.016
lymphocyte activation involved in immune responseGO:0002285930.016
negative regulation of intracellular signal transductionGO:19025321670.016
regulation of cell projection organizationGO:00313442060.016
cytoplasmic transportGO:00164822340.016
sodium ion transportGO:0006814730.016
chloride transportGO:0006821320.015
multicellular organismal homeostasisGO:00488711640.015
purine containing compound catabolic processGO:00725232130.015
calcitriol biosynthetic process from calciolGO:003637830.015
ribonucleoside catabolic processGO:00424542060.015
sterol homeostasisGO:0055092450.015
positive regulation of ion transportGO:0043270650.015
negative regulation of protein processingGO:0010955790.015
meiotic cell cycle processGO:1903046770.015
regulation of blood pressureGO:0008217930.015
negative regulation of cell proliferationGO:00082852960.015
plasma membrane organizationGO:0007009900.015
positive regulation of programmed cell deathGO:00430682180.015
epithelial cell developmentGO:00020641590.015
regulation of defense responseGO:00313472330.015
positive regulation of vasoconstrictionGO:004590740.015
cellular protein complex assemblyGO:00436231160.015
compound eye developmentGO:004874910.015
cellular calcium ion homeostasisGO:00068741190.015
organelle fissionGO:00482851700.015
t cell mediated immunityGO:0002456500.015
leukocyte migrationGO:00509001240.015
regulation of cellular component sizeGO:00325351210.015
regulation of protein kinase activityGO:00458592320.015
fatty acid metabolic processGO:00066311210.015
regulation of proteolysisGO:00301621640.014
amide transportGO:00428861380.014
urogenital system developmentGO:00016552610.014
regulation of systemic arterial blood pressureGO:0003073610.014
response to oxygen levelsGO:0070482620.014
single organism cell adhesionGO:00986021560.014
cellular alcohol metabolic processGO:004410730.014
rho protein signal transductionGO:0007266320.014
sequestering of calcium ionGO:0051208180.014
cardiac muscle fiber developmentGO:004873940.014
camera type eye developmentGO:00430102660.014
striated muscle myosin thick filament assemblyGO:007168810.014
sulfur compound metabolic processGO:00067901000.014
nucleoside monophosphate metabolic processGO:0009123850.014
muscle cell differentiationGO:00426922610.014
forebrain developmentGO:00309003020.014
humoral immune responseGO:0006959570.014
developmental maturationGO:00217001930.014
response to extracellular stimulusGO:00099911270.014
symbiosis encompassing mutualism through parasitismGO:0044403830.014
nuclear divisionGO:00002801580.014
immune response regulating signaling pathwayGO:00027641250.014
regulation of kinase activityGO:00435492490.014
exocytosisGO:00068871210.014
stem cell differentiationGO:00488632680.014
norepinephrine secretionGO:004824320.014
regulation of intracellular transportGO:00323861590.014
muscle contractionGO:00069361010.014
neuronal action potentialGO:0019228540.014
Mouse
nucleocytoplasmic transportGO:00069131390.013
regulation of mapk cascadeGO:00434082480.013
cellular alcohol biosynthetic processGO:004410830.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
blood vessel morphogenesisGO:00485142850.013
inflammatory responseGO:00069542440.013
Mouse
vitamin transmembrane transportGO:003546140.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
lipid transportGO:0006869980.013
negative regulation of multi organism processGO:0043901680.013
hematopoietic progenitor cell differentiationGO:00022441430.013
purine nucleotide catabolic processGO:00061952110.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
vitamin d3 metabolic processGO:007064030.013
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.013
cellular response to growth factor stimulusGO:00713631970.013
regulation of ion transmembrane transportGO:00347651190.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
regulation of angiotensin levels in bloodGO:000200240.013
carbohydrate transportGO:0008643620.013
digestionGO:0007586400.013
regulation of response to woundingGO:19030341890.013
Rat
chloride transmembrane transportGO:1902476240.013
regulation of antimicrobial peptide productionGO:000278410.013
mitotic cell cycleGO:00002781950.013
regulation of cytokine secretionGO:0050707610.013
protein catabolic processGO:00301632210.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
response to nutrient levelsGO:00316671090.013
carbohydrate derivative catabolic processGO:19011362310.013
response to inorganic substanceGO:0010035960.013
positive regulation of cell motilityGO:20001471160.013
regulation of leukocyte differentiationGO:19021051590.013
myosin filament assemblyGO:003103420.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
extracellular matrix organizationGO:00301981470.013
synaptic transmissionGO:00072683290.013
purine nucleoside catabolic processGO:00061522050.012
single fertilizationGO:0007338820.012
regulation of feeding behaviorGO:006025930.012
striated muscle tissue developmentGO:00147062930.012
regulation of muscle system processGO:0090257800.012
positive regulation of transferase activityGO:00513471670.012
regulation of norepinephrine secretionGO:001406120.012
defense response to other organismGO:00985421970.012
renal system developmentGO:00720012250.012
antimicrobial peptide biosynthetic processGO:000277720.012
regulation of mitotic cell cycleGO:00073461260.012
negative regulation of cell activationGO:00508661110.012
microtubule based processGO:00070172360.012
cellular response to extracellular stimulusGO:0031668810.012
regulation of apoptotic signaling pathwayGO:20012331970.012
ribonucleotide catabolic processGO:00092612080.012
spermatid differentiationGO:00485151150.012
oligopeptide transmembrane transportGO:003567240.012
atp metabolic processGO:0046034750.012
regulation of inflammatory responseGO:00507271470.012
mitotic cell cycle processGO:19030471590.012
regulation of t cell proliferationGO:0042129920.012
small molecule biosynthetic processGO:00442831320.012
cytosolic calcium ion homeostasisGO:0051480700.012
regulation of cell migrationGO:00303342190.012
circadian rhythmGO:00076231140.012
cytokine secretionGO:0050663720.012
organelle localizationGO:00516401790.012
antimicrobial peptide productionGO:000277520.012
regulation of synaptic growth at neuromuscular junctionGO:000858240.012
spermatid developmentGO:00072861080.012
regulation of phGO:0006885260.012
regulation of vasculature developmentGO:1901342880.012
epithelial cell proliferationGO:00506731740.012
immune response activating cell surface receptor signaling pathwayGO:0002429720.012
purine ribonucleotide catabolic processGO:00091542080.012
t cell differentiationGO:00302171740.012
purine ribonucleoside catabolic processGO:00461302050.012
positive regulation of secretion by cellGO:19035321140.012
protein localization to membraneGO:00726571080.012
cell maturationGO:00484691270.012
negative regulation of protein modification processGO:00314001630.012
i kappab kinase nf kappab signalingGO:0007249850.012
wnt signaling pathwayGO:00160551880.012
dephosphorylationGO:00163111290.012
positive regulation of mapk cascadeGO:00434101700.012
exogenous drug catabolic processGO:004273810.012
tissue homeostasisGO:00018941150.012
coenzyme metabolic processGO:0006732520.012
protein secretionGO:00093061110.012
cellular macromolecule catabolic processGO:00442652060.012
nucleoside triphosphate catabolic processGO:00091432050.011
cytokinetic processGO:003250620.011
negative regulation of peptidase activityGO:0010466460.011
positive regulation of hydrolase activityGO:00513451480.011
adult behaviorGO:00305341350.011
response to growth factorGO:00708481980.011
response to organonitrogen compoundGO:00102432460.011
myeloid leukocyte differentiationGO:00025731190.011
Mouse
regulation of bindingGO:00510981110.011
positive regulation of apoptotic processGO:00430652170.011
erk1 and erk2 cascadeGO:0070371770.011
columnar cuboidal epithelial cell differentiationGO:0002065820.011
regulation of leukocyte mediated immunityGO:00027031040.011
organic hydroxy compound biosynthetic processGO:1901617770.011
digestive tract developmentGO:00485651900.011
regulation of peptidase activityGO:0052547960.011
cellular response to lipopolysaccharideGO:0071222770.011
regulation of renal sodium excretionGO:003581330.011
cellular response to molecule of bacterial originGO:0071219830.011
monosaccharide transportGO:0015749580.011
regulation of cytoskeleton organizationGO:00514931220.011
regulation of protein transportGO:00512231630.011
mapk cascadeGO:00001652810.011
negative regulation of phosphorylationGO:00423261660.011
thrombin receptor signaling pathwayGO:007049320.011
hormone secretionGO:00468791280.011
negative regulation of cytokine productionGO:0001818840.011
regulation of chemokine secretionGO:009019640.011
regulation of neuron projection developmentGO:00109751690.011
positive regulation of phagocytosis engulfmentGO:006010030.011
muscle tissue developmentGO:00605373080.011
axonogenesisGO:00074092740.011
regulation of defense response to bacteriumGO:190042430.011
negative regulation of lymphocyte activationGO:0051250910.011
positive regulation of neutrophil mediated cytotoxicityGO:007096010.011
hemostasisGO:0007599780.011
Rat
heart morphogenesisGO:00030071780.011
carbohydrate homeostasisGO:00335001280.011
ossificationGO:00015032160.011
lipid homeostasisGO:0055088630.011
activation of transmembrane receptor protein tyrosine kinase activityGO:000717130.011
rna processingGO:00063961050.011
sodium ion transmembrane transportGO:0035725490.011
positive regulation of cytokine productionGO:00018191740.011
peptide transportGO:00158331330.011
mitotic chromosome condensationGO:000707610.011
cellular response to oxidative stressGO:0034599760.011
organelle assemblyGO:00709251770.011
regulation of neuron differentiationGO:00456642810.011
meiotic cell cycleGO:00513211220.011
positive regulation of innate immune responseGO:0045089800.011
purine ribonucleotide metabolic processGO:00091502900.011
positive regulation of neutrophil mediated killing of symbiont cellGO:007096110.011
negative regulation of t cell activationGO:0050868650.010
protein localization to plasma membraneGO:0072659570.010
regulation of cellular response to growth factor stimulusGO:0090287820.010
cellular component assembly involved in morphogenesisGO:00109271390.010
actin polymerization or depolymerizationGO:0008154540.010
phenol containing compound metabolic processGO:0018958600.010
cellular response to acid chemicalGO:0071229680.010
regulation of ion homeostasisGO:2000021640.010
regulation of chloride transportGO:200122520.010
neutrophil mediated killing of gram negative bacteriumGO:007094540.010
cellular response to hormone stimulusGO:00328701500.010
regionalizationGO:00030023370.010
regulation of cell cycle processGO:00105641600.010
myeloid leukocyte activationGO:0002274830.010
positive regulation of cell deathGO:00109422240.010
multi multicellular organism processGO:00447061090.010
inter male aggressive behaviorGO:000212130.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
extrinsic apoptotic signaling pathwayGO:00971911260.010
membrane depolarizationGO:0051899640.010
glycerolipid metabolic processGO:00464861220.010
regulation of blood circulationGO:1903522930.010
leukocyte chemotaxisGO:0030595690.010
regulation of purine nucleotide metabolic processGO:19005421690.010
generation of precursor metabolites and energyGO:00060911030.010
organic acid biosynthetic processGO:0016053860.010

Tspan8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
organ system cancerDOID:005068600.014
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
musculoskeletal system diseaseDOID:1700.013
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012