Mus musculus

7 known processes

Mmp1b

matrix metallopeptidase 1b (interstitial collagenase)

(Aliases: Mcolb,Mcol-B)

Mmp1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transforming growth factor beta secretionGO:200120310.173
negative regulation of blood vessel endothelial cell migrationGO:004353730.128
transforming growth factor beta secretionGO:003804410.126
negative regulation of endothelial cell migrationGO:001059640.088
regulation of membrane potentialGO:00423911920.082
regulation of microvillus organizationGO:003253030.077
carbohydrate metabolic processGO:00059752300.076
regulation of transforming growth factor beta secretionGO:200120110.076
monosaccharide metabolic processGO:00059961060.073
cellular amine metabolic processGO:0044106440.073
macromolecule catabolic processGO:00090572810.073
Mouse
response to organonitrogen compoundGO:00102432460.072
regulation of cell projection organizationGO:00313442060.070
regulation of cell motilityGO:20001452360.070
regulation of cellular ketone metabolic processGO:0010565660.069
regulation of microvillus assemblyGO:003253430.069
cellular response to lipidGO:00713961450.065
hexose metabolic processGO:0019318980.062
muscle tissue developmentGO:00605373080.061
regulation of cellular amino acid metabolic processGO:000652150.061
positive regulation of secretion by cellGO:19035321140.055
regulation of secretionGO:00510462740.053
nitrogen compound transportGO:00717052710.052
muscle cell differentiationGO:00426922610.051
cellular response to organonitrogen compoundGO:00714171450.050
cellular ketone metabolic processGO:0042180840.048
striated muscle tissue developmentGO:00147062930.048
response to peptideGO:19016521360.045
spermatogenesisGO:00072832840.045
myotube differentiationGO:00149021050.044
regulation of transferase activityGO:00513382630.043
protein maturationGO:00516041760.043
cellular chemical homeostasisGO:00550822150.042
male gamete generationGO:00482322850.042
positive regulation of nervous system developmentGO:00519622210.042
leukocyte mediated immunityGO:00024431740.042
cellular response to hormone stimulusGO:00328701500.042
negative regulation of cellular protein metabolic processGO:00322692470.041
blood vessel morphogenesisGO:00485142850.040
positive regulation of protein modification processGO:00314012990.039
cell type specific apoptotic processGO:00972852680.039
angiogenesisGO:00015252010.039
sensory organ morphogenesisGO:00905962420.039
regulation of kinase activityGO:00435492490.038
positive regulation of cell developmentGO:00107202370.038
multicellular organismal signalingGO:0035637910.038
cellular homeostasisGO:00197252400.038
response to peptide hormoneGO:00434341270.036
regulation of body fluid levelsGO:00508781620.035
positive regulation of transferase activityGO:00513471670.035
transmembrane transportGO:00550854120.034
oxidation reduction processGO:00551143420.034
striated muscle cell developmentGO:00550021250.034
regulation of protein transportGO:00512231630.034
cellular response to peptideGO:1901653920.033
immune effector processGO:00022523210.033
regulation of interleukin 10 secretionGO:200117940.033
regulation of muscle tissue developmentGO:1901861970.033
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.033
defense response to bacteriumGO:00427421190.032
positive regulation of cell projection organizationGO:0031346950.032
muscle fiber developmentGO:0048747760.032
cellular lipid metabolic processGO:00442553230.032
action potentialGO:0001508780.031
cellular response to peptide hormone stimulusGO:0071375920.031
regulation of heart contractionGO:0008016770.031
cellular response to organic cyclic compoundGO:0071407870.030
cellular amino acid metabolic processGO:00065201030.030
protein catabolic processGO:00301632210.030
Mouse
apoptotic signaling pathwayGO:00971903060.030
lymphocyte mediated immunityGO:00024491390.030
amine metabolic processGO:0009308450.029
b cell activationGO:00421131610.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.029
wound healingGO:00420601570.028
response to organic cyclic compoundGO:00140701980.028
regulation of neuron projection developmentGO:00109751690.028
cellular response to testosterone stimulusGO:007139410.028
leukocyte differentiationGO:00025213420.027
production of molecular mediator of immune responseGO:00024401030.027
regulation of hydrolase activityGO:00513362460.027
skeletal muscle organ developmentGO:00605381630.027
adaptive immune responseGO:00022501550.027
placenta developmentGO:00018901400.027
positive regulation of cellular amine metabolic processGO:003324050.027
cellular response to cytokine stimulusGO:00713451890.027
regulation of feeding behaviorGO:006025930.027
regulation of response to woundingGO:19030341890.026
sprouting angiogenesisGO:0002040260.026
multicellular organism growthGO:00352641610.026
anion transportGO:00068201770.026
regulation of secretion by cellGO:19035302490.026
muscle cell developmentGO:00550011330.026
positive regulation of cell motilityGO:20001471160.026
cation transportGO:00068123990.026
skeletal muscle fiber developmentGO:0048741580.026
ion transmembrane transportGO:00342203610.025
cytokine productionGO:00018163190.025
cellular response to steroid hormone stimulusGO:0071383330.025
positive regulation of secretionGO:00510471300.025
carbohydrate derivative biosynthetic processGO:19011371830.025
glucose homeostasisGO:00425931280.025
lymphocyte differentiationGO:00300982420.025
regulation of protein localizationGO:00328802310.025
regulation of epithelial cell proliferationGO:00506781410.025
regulation of vesicle mediated transportGO:00606271390.024
cell adhesionGO:00071553290.024
monocarboxylic acid metabolic processGO:00327871910.024
t cell mediated immunityGO:0002456500.024
positive regulation of cell migrationGO:00303351090.024
cation homeostasisGO:00550802120.024
response to oxygen levelsGO:0070482620.024
negative regulation of protein metabolic processGO:00512482820.024
sensory perceptionGO:00076002450.024
nuclear transportGO:00511691390.024
regulation of cellular amine metabolic processGO:0033238200.023
chemotaxisGO:00069352470.023
positive regulation of cytokine productionGO:00018191740.023
diacylglycerol biosynthetic processGO:000665120.023
forebrain developmentGO:00309003020.023
positive regulation of protein phosphorylationGO:00019342420.023
heart processGO:0003015940.023
respiratory system developmentGO:00605411900.023
maintenance of locationGO:0051235890.022
skin developmentGO:00435882200.022
carboxylic acid transportGO:00469421000.022
myotube cell developmentGO:0014904600.022
regulation of myotube differentiationGO:0010830620.021
negative regulation of cell developmentGO:00107211690.021
regulation of angiotensin levels in bloodGO:000200240.021
response to lipopolysaccharideGO:00324961280.021
glucose metabolic processGO:0006006920.021
response to extracellular stimulusGO:00099911270.021
positive regulation of apoptotic processGO:00430652170.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
regulation of cell cycleGO:00517262810.021
regulation of myoblast differentiationGO:0045661290.020
t cell activationGO:00421102890.020
glycoprotein biosynthetic processGO:0009101890.020
steroid metabolic processGO:00082021190.020
transmission of nerve impulseGO:0019226760.020
lipid localizationGO:00108761260.020
norepinephrine secretionGO:004824320.020
regulation of cellular response to stressGO:00801351590.020
extracellular structure organizationGO:00430621480.020
Mouse
positive regulation of cell deathGO:00109422240.020
defense response to gram positive bacteriumGO:0050830500.020
regulation of neuron differentiationGO:00456642810.020
regulation of establishment of protein localizationGO:00702011810.020
establishment of blood nerve barrierGO:000806530.020
inorganic cation transmembrane transportGO:00986622070.020
camera type eye developmentGO:00430102660.020
negative regulation of cellular amine metabolic processGO:003323910.019
glycoprotein metabolic processGO:00091001160.019
rhythmic processGO:00485111740.019
negative regulation of cell motilityGO:2000146610.019
cellular macromolecule catabolic processGO:00442652060.019
regulation of hormone levelsGO:00108172110.019
ensheathment of neuronsGO:0007272760.019
amide transportGO:00428861380.019
response to insulinGO:00328681000.019
axonogenesisGO:00074092740.019
organic acid transportGO:00158491010.019
cell activation involved in immune responseGO:00022631260.019
leukocyte activation involved in immune responseGO:00023661260.019
hematopoietic progenitor cell differentiationGO:00022441430.018
Mouse
inter male aggressive behaviorGO:000212130.018
peptidyl amino acid modificationGO:00181933360.018
ossificationGO:00015032160.018
morphogenesis of a branching structureGO:00017632030.018
positive regulation of neuron differentiationGO:00456661410.018
embryonic placenta developmentGO:0001892980.018
response to nutrient levelsGO:00316671090.018
myoblast differentiationGO:0045445520.018
protein processingGO:00164851630.018
symbiosis encompassing mutualism through parasitismGO:0044403830.018
posttranscriptional regulation of gene expressionGO:00106081550.018
response to molecule of bacterial originGO:00022371430.018
regulation of striated muscle cell differentiationGO:0051153810.018
cardiac muscle tissue developmentGO:00487381300.018
inflammatory responseGO:00069542440.018
regulation of vasculature developmentGO:1901342880.018
eye photoreceptor cell developmentGO:0042462310.018
carbohydrate homeostasisGO:00335001280.018
central nervous system neuron differentiationGO:00219531620.018
small molecule biosynthetic processGO:00442831320.017
chromatin organizationGO:00063252060.017
cellular ion homeostasisGO:00068731650.017
ameboidal type cell migrationGO:00016671280.017
positive regulation of protein transportGO:0051222930.017
regulation of carbohydrate metabolic processGO:0006109750.017
circulatory system processGO:00030131970.017
multi multicellular organism processGO:00447061090.017
response to acid chemicalGO:00011011110.017
interleukin 10 secretionGO:007260840.017
regulation of lymphocyte activationGO:00512492400.017
aromatic compound catabolic processGO:00194392860.017
protein secretionGO:00093061110.017
positive regulation of programmed cell deathGO:00430682180.017
regulation of organelle organizationGO:00330432890.017
cellular response to insulin stimulusGO:0032869780.017
regulation of system processGO:00440572000.017
positive regulation of angiogenesisGO:0045766460.017
cation transmembrane transportGO:00986552660.017
interspecies interaction between organismsGO:0044419830.017
regulation of protein processingGO:0070613960.016
response to steroid hormoneGO:0048545560.016
cd4 positive alpha beta t cell cytokine productionGO:003574340.016
developmental growth involved in morphogenesisGO:00605601380.016
sequestering of metal ionGO:0051238190.016
cellular nitrogen compound catabolic processGO:00442702800.016
regulation of cell activationGO:00508652890.016
anatomical structure homeostasisGO:00602491450.016
macromolecule glycosylationGO:0043413550.016
blood circulationGO:00080151950.016
exocytosisGO:00068871210.016
regulation of angiotensin metabolic processGO:006017740.016
response to amino acidGO:0043200370.016
regulation of cellular component biogenesisGO:00440871810.016
Human
cellular response to carbohydrate stimulusGO:0071322500.016
regulation of action potentialGO:009890040.016
positive regulation of immune effector processGO:00026991070.016
negative regulation of phosphorus metabolic processGO:00105631840.016
regulation of protein maturationGO:1903317960.016
nucleoside phosphate catabolic processGO:19012922220.016
epidermis developmentGO:00085441870.016
lipid biosynthetic processGO:00086101790.016
ras protein signal transductionGO:0007265770.016
positive regulation of defense responseGO:00313491240.016
cellular carbohydrate metabolic processGO:00442621190.016
neuron deathGO:00709971540.016
muscle system processGO:00030121410.015
retinoid metabolic processGO:0001523240.015
cellular response to nutrient levelsGO:0031669640.015
organic anion transportGO:00157111370.015
myeloid cell differentiationGO:00300992330.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
regulation of protein kinase activityGO:00458592320.015
chromatin modificationGO:00165681870.015
small gtpase mediated signal transductionGO:0007264970.015
regulation of cellular carbohydrate metabolic processGO:0010675750.015
regulation of leukocyte differentiationGO:19021051590.015
regulation of defense responseGO:00313472330.015
carbohydrate biosynthetic processGO:0016051740.015
negative regulation of molecular functionGO:00440922580.015
positive regulation of kinase activityGO:00336741550.015
regulation of proteolysisGO:00301621640.015
negative regulation of vasculature developmentGO:1901343260.015
neuron neuron synaptic transmissionGO:0007270690.015
negative regulation of muscle cell differentiationGO:0051148330.015
mapk cascadeGO:00001652810.015
cellular response to molecule of bacterial originGO:0071219830.015
carbohydrate derivative catabolic processGO:19011362310.015
rho protein signal transductionGO:0007266320.015
stem cell proliferationGO:00720891170.015
divalent metal ion transportGO:00708381720.015
myeloid leukocyte mediated immunityGO:0002444420.015
dephosphorylationGO:00163111290.015
positive regulation of inflammatory responseGO:0050729470.014
response to monosaccharideGO:0034284670.014
protein localization to organelleGO:00333651850.014
photoreceptor cell differentiationGO:0046530520.014
ear developmentGO:00435832000.014
lymphocyte activation involved in immune responseGO:0002285930.014
photoreceptor cell developmentGO:0042461400.014
positive regulation of protein secretionGO:0050714520.014
regulation of cellular component sizeGO:00325351210.014
b cell differentiationGO:0030183780.014
negative regulation of blood vessel morphogenesisGO:2000181250.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
cellular response to extracellular stimulusGO:0031668810.014
regulation of angiogenesisGO:0045765810.014
cerebral cortex developmentGO:0021987860.014
negative regulation of growthGO:0045926990.014
cytoplasmic transportGO:00164822340.014
gland developmentGO:00487323300.014
heterocycle catabolic processGO:00467002800.014
negative regulation of protein modification processGO:00314001630.014
regulation of cytokine secretionGO:0050707610.014
regulation of lymphocyte differentiationGO:00456191070.014
response to inorganic substanceGO:0010035960.014
asymmetric stem cell divisionGO:009872230.014
photoreceptor cell morphogenesisGO:000859430.013
regulation of exocytosisGO:0017157610.013
activation of nf kappab inducing kinase activityGO:000725040.013
negative regulation of myoblast differentiationGO:0045662180.013
tissue remodelingGO:00487711020.013
tissue migrationGO:0090130680.013
generation of precursor metabolites and energyGO:00060911030.013
regulation of cell migrationGO:00303342190.013
protein modification by small protein conjugationGO:00324461870.013
positive regulation of response to woundingGO:1903036660.013
androgen biosynthetic processGO:000670240.013
neuronal action potentialGO:0019228540.013
regulation of cell projection assemblyGO:0060491380.013
cellular response to acid chemicalGO:0071229680.013
peptide metabolic processGO:0006518460.013
regulation of coagulationGO:0050818310.013
epithelial cell developmentGO:00020641590.013
regulation of multi organism processGO:00439001110.013
positive regulation of neural precursor cell proliferationGO:2000179420.013
negative regulation of phosphorylationGO:00423261660.013
regulation of skeletal muscle fiber developmentGO:0048742360.013
regulation of lipid metabolic processGO:00192161180.013
immunoglobulin productionGO:0002377730.013
response to transforming growth factor betaGO:0071559880.013
spermatid differentiationGO:00485151150.013
negative regulation of angiogenesisGO:0016525250.013
cellular response to starvationGO:0009267570.013
negative regulation of immune system processGO:00026832090.013
olfactory learningGO:000835520.013
peptide secretionGO:00027901140.013
insulin receptor signaling pathwayGO:0008286490.013
glycerolipid metabolic processGO:00464861220.013
cell growthGO:00160491300.013
neutrophil mediated killing of gram positive bacteriumGO:007094620.012
connective tissue developmentGO:00614481790.012
positive regulation of growthGO:00459271040.012
inorganic ion transmembrane transportGO:00986602340.012
regulation of norepinephrine secretionGO:001406120.012
eye photoreceptor cell differentiationGO:0001754410.012
monosaccharide transportGO:0015749580.012
negative regulation of proteolysisGO:0045861740.012
cellular response to biotic stimulusGO:0071216920.012
regulation of wound healingGO:0061041400.012
regulation of production of molecular mediator of immune responseGO:0002700650.012
neural precursor cell proliferationGO:00613511210.012
cell growth involved in cardiac muscle cell developmentGO:006104930.012
morphogenesis of a branching epitheliumGO:00611381930.012
positive regulation of cytokine secretionGO:0050715410.012
nuclear divisionGO:00002801580.012
glycosylationGO:0070085620.012
response to vitamin dGO:003328030.012
negative regulation of carbohydrate metabolic processGO:0045912190.012
fatty acid metabolic processGO:00066311210.012
t cell activation involved in immune responseGO:0002286430.012
cellular response to growth factor stimulusGO:00713631970.012
conditioned taste aversionGO:000166140.012
organonitrogen compound catabolic processGO:19015652640.012
regulation of phospholipase a2 activityGO:003242930.012
negative regulation of protein processingGO:0010955790.012
negative regulation of protein maturationGO:1903318790.012
gonad developmentGO:00084061410.012
activation of immune responseGO:00022531380.012
regulation of ion transportGO:00432692150.012
organelle fissionGO:00482851700.012
negative regulation of endopeptidase activityGO:0010951440.012
reactive oxygen species metabolic processGO:0072593840.012
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.012
regulation of homeostatic processGO:00328441820.012
positive regulation of ubiquitin protein transferase activityGO:005144340.012
regulation of protein oligomerizationGO:003245940.012
Human
positive regulation of protein kinase activityGO:00458601440.012
leukocyte chemotaxisGO:0030595690.012
mature natural killer cell chemotaxisGO:003578210.012
positive regulation of cell activationGO:00508671580.012
regulation of cytokine productionGO:00018172660.012
cytokine secretionGO:0050663720.012
organic hydroxy compound metabolic processGO:19016152030.012
negative regulation of cellular carbohydrate metabolic processGO:0010677190.012
axon ensheathmentGO:0008366760.011
stem cell developmentGO:00488642190.011
synaptic transmissionGO:00072683290.011
coagulationGO:0050817780.011
epithelial cell proliferationGO:00506731740.011
protein ubiquitinationGO:00165671710.011
regulation of cell sizeGO:0008361720.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
extracellular matrix organizationGO:00301981470.011
Mouse
activation of transmembrane receptor protein tyrosine kinase activityGO:000717130.011
respiratory tube developmentGO:00303231670.011
regulation of peptidase activityGO:0052547960.011
glucuronate metabolic processGO:001958520.011
regulation of cell growthGO:0001558910.011
gluconeogenesisGO:0006094390.011
diterpenoid metabolic processGO:0016101240.011
blood vessel endothelial cell migrationGO:0043534230.011
sequestering of calcium ionGO:0051208180.011
nucleoside triphosphate catabolic processGO:00091432050.011
regulation of endopeptidase activityGO:0052548890.011
positive regulation of lymphocyte activationGO:00512511400.011
blood coagulationGO:0007596760.011
carbohydrate transportGO:0008643620.011
response to radiationGO:00093141650.011
positive regulation of cd4 positive alpha beta t cell proliferationGO:200056310.011
positive regulation of epithelial cell proliferationGO:0050679680.011
cellular response to glucose stimulusGO:0071333450.011
nucleotide catabolic processGO:00091662170.011
multicellular organismal homeostasisGO:00488711640.011
protein modification by small protein conjugation or removalGO:00706472070.011
response to oxidative stressGO:00069791230.011
leukocyte mediated cytotoxicityGO:0001909620.011
protein glycosylationGO:0006486550.011
positive regulation of keratinocyte proliferationGO:001083840.011
ribonucleoside catabolic processGO:00424542060.011
response to growth factorGO:00708481980.011
regulation of peptide transportGO:0090087910.011
multi organism behaviorGO:0051705620.011
cellular response to monosaccharide stimulusGO:0071326470.011
hemostasisGO:0007599780.011
physiological cardiac muscle hypertrophyGO:000330130.010
peptide hormone secretionGO:00300721090.010
positive regulation of stem cell proliferationGO:2000648590.010
regulation of adaptive immune responseGO:0002819900.010
purine nucleotide metabolic processGO:00061633020.010
negative regulation of intracellular signal transductionGO:19025321670.010
cellular response to hexose stimulusGO:0071331470.010
purine nucleoside triphosphate catabolic processGO:00091462030.010
fat cell differentiationGO:00454441600.010
cellular metal ion homeostasisGO:00068751510.010
nucleobase containing small molecule metabolic processGO:00550863520.010
response to decreased oxygen levelsGO:0036293590.010
organic cyclic compound catabolic processGO:19013612950.010
ovulation cycleGO:0042698590.010
negative regulation of transferase activityGO:0051348850.010
positive regulation of leukocyte proliferationGO:0070665730.010
regulation of muscle system processGO:0090257800.010
ribonucleoside metabolic processGO:00091192450.010
calcium ion dependent exocytosisGO:0017156350.010
regulation of glucose metabolic processGO:0010906600.010
positive regulation of protein oligomerizationGO:003246140.010
Human
dna metabolic processGO:00062593030.010
cellular protein catabolic processGO:00442571550.010
response to testosteroneGO:003357430.010
isoprenoid metabolic processGO:0006720290.010

Mmp1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
nervous system diseaseDOID:86300.042
disease of metabolismDOID:001466700.034
sensory system diseaseDOID:005015500.025
eye and adnexa diseaseDOID:149200.023
musculoskeletal system diseaseDOID:1700.022
inherited metabolic disorderDOID:65500.018
eye diseaseDOID:561400.017
connective tissue diseaseDOID:6500.016
bone diseaseDOID:008000100.016
retinal diseaseDOID:567900.014
neurodegenerative diseaseDOID:128900.010
central nervous system diseaseDOID:33100.010