Mus musculus

86 known processes

Usp21

ubiquitin specific peptidase 21

(Aliases: ESTM28,Usp23,Usp16,W53272)

Usp21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin modificationGO:00165681870.276
histone methylationGO:0016571710.257
covalent chromatin modificationGO:00165691630.198
negative regulation of molecular functionGO:00440922580.192
nucleobase containing small molecule metabolic processGO:00550863520.151
histone modificationGO:00165701590.112
chromatin organizationGO:00063252060.103
skeletal system developmentGO:00015013560.099
ribonucleoside catabolic processGO:00424542060.086
ribonucleoside triphosphate metabolic processGO:00091992200.081
regulation of cell cycleGO:00517262810.080
macromolecule catabolic processGO:00090572810.077
Yeast Fly
histone lysine methylationGO:0034968500.075
negative regulation of cell proliferationGO:00082852960.074
organic cyclic compound catabolic processGO:19013612950.072
defense response to other organismGO:00985421970.072
Fly
urogenital system developmentGO:00016552610.072
ribonucleotide metabolic processGO:00092592910.071
protein alkylationGO:0008213810.070
regulation of cellular ketone metabolic processGO:0010565660.068
purine ribonucleotide metabolic processGO:00091502900.067
camera type eye developmentGO:00430102660.067
methylationGO:00322591340.065
spermatogenesisGO:00072832840.065
heterocycle catabolic processGO:00467002800.065
cellular response to dna damage stimulusGO:00069742070.064
response to organic cyclic compoundGO:00140701980.064
cellular macromolecule catabolic processGO:00442652060.063
Yeast Fly
cilium morphogenesisGO:00602711020.062
protein methylationGO:0006479810.061
male gamete generationGO:00482322850.060
organonitrogen compound catabolic processGO:19015652640.060
protein localization to organelleGO:00333651850.059
purine containing compound metabolic processGO:00725213110.057
synaptonemal complex assemblyGO:0007130130.057
regulation of bindingGO:00510981110.056
peptidyl amino acid modificationGO:00181933360.055
synapsisGO:0007129340.055
purine nucleoside triphosphate metabolic processGO:00091442260.055
nucleoside triphosphate metabolic processGO:00091412300.054
regulation of proteolysisGO:00301621640.054
Fly
cytokine productionGO:00018163190.053
regulation of cell cycle processGO:00105641600.052
negative regulation of phosphate metabolic processGO:00459361840.052
modification dependent protein catabolic processGO:00199411330.052
Yeast
innate immune responseGO:00450871570.051
Fly
nucleotide catabolic processGO:00091662170.051
negative regulation of protein metabolic processGO:00512482820.051
carbohydrate metabolic processGO:00059752300.051
dna alkylationGO:0006305430.050
nucleoside phosphate catabolic processGO:19012922220.050
aromatic compound catabolic processGO:00194392860.049
protein ubiquitinationGO:00165671710.048
skeletal system morphogenesisGO:00487052030.048
protein localization to nucleusGO:00345041210.048
intracellular protein transportGO:00068862040.048
carbohydrate derivative catabolic processGO:19011362310.048
glycosyl compound metabolic processGO:19016572460.047
positive regulation of proteolysisGO:0045862850.047
Fly
synaptonemal complex organizationGO:0070193150.047
cellular nitrogen compound catabolic processGO:00442702800.046
purine nucleoside triphosphate catabolic processGO:00091462030.046
regulation of protein localizationGO:00328802310.046
gland developmentGO:00487323300.045
purine containing compound catabolic processGO:00725232130.044
protein modification by small protein conjugation or removalGO:00706472070.044
macromolecule methylationGO:00434141200.044
renal system developmentGO:00720012250.043
nucleoside triphosphate catabolic processGO:00091432050.043
cellular amino acid metabolic processGO:00065201030.043
lens development in camera type eyeGO:0002088620.042
nucleoside catabolic processGO:00091642060.041
response to acid chemicalGO:00011011110.040
positive regulation of programmed cell deathGO:00430682180.039
response to organonitrogen compoundGO:00102432460.039
protein importGO:00170381010.039
regulation of hydrolase activityGO:00513362460.039
positive regulation of apoptotic processGO:00430652170.039
negative regulation of intracellular signal transductionGO:19025321670.039
regulation of cytokine productionGO:00018172660.038
purine ribonucleoside catabolic processGO:00461302050.038
cellular ketone metabolic processGO:0042180840.038
ribonucleoside triphosphate catabolic processGO:00092031990.037
tube closureGO:0060606910.037
neural tube developmentGO:00219151600.037
tube formationGO:00351481400.036
ribose phosphate metabolic processGO:00196932910.036
cellular protein catabolic processGO:00442571550.036
Yeast Fly
cellular response to lipidGO:00713961450.035
multi multicellular organism processGO:00447061090.035
homeostasis of number of cellsGO:00488722100.035
nucleoside phosphate metabolic processGO:00067533380.034
epithelial tube formationGO:00721751300.034
positive regulation of cell deathGO:00109422240.034
purine ribonucleoside triphosphate catabolic processGO:00092071990.034
response to molecule of bacterial originGO:00022371430.034
positive regulation of bindingGO:0051099490.034
embryonic appendage morphogenesisGO:00351131260.034
purine nucleoside catabolic processGO:00061522050.033
cilium assemblyGO:0042384810.033
guanosine containing compound catabolic processGO:19010691440.033
apoptotic signaling pathwayGO:00971903060.033
purine nucleotide metabolic processGO:00061633020.032
positive regulation of hydrolase activityGO:00513451480.032
regulation of apoptotic signaling pathwayGO:20012331970.031
gtp catabolic processGO:00061841430.030
primary neural tube formationGO:0014020950.030
protein maturationGO:00516041760.030
nucleoside metabolic processGO:00091162460.030
cellular amine metabolic processGO:0044106440.030
protein targetingGO:00066051430.030
negative regulation of nervous system developmentGO:00519611560.029
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.029
regulation of protein kinase activityGO:00458592320.029
guanosine containing compound metabolic processGO:19010681440.029
gtp metabolic processGO:00460391440.028
cellular carbohydrate metabolic processGO:00442621190.028
regulation of purine nucleotide metabolic processGO:19005421690.028
histone h4 k16 acetylationGO:004398430.028
synaptic transmissionGO:00072683290.028
mitotic cell cycle processGO:19030471590.027
regulation of antimicrobial humoral responseGO:000275930.027
Fly
purine ribonucleotide catabolic processGO:00091542080.027
posttranscriptional regulation of gene expressionGO:00106081550.027
purine ribonucleoside triphosphate metabolic processGO:00092052200.026
embryonic epithelial tube formationGO:00018381300.026
negative regulation of cellular protein metabolic processGO:00322692470.026
fat cell differentiationGO:00454441600.026
ubiquitin dependent protein catabolic processGO:00065111290.026
Yeast
dna modificationGO:0006304500.026
small gtpase mediated signal transductionGO:0007264970.026
Mouse
kidney developmentGO:00018222130.025
blood vessel morphogenesisGO:00485142850.025
peptidyl lysine modificationGO:0018205770.025
forebrain developmentGO:00309003020.025
negative regulation of kinase activityGO:0033673810.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
nuclear divisionGO:00002801580.025
regulation of transferase activityGO:00513382630.024
midbrain developmentGO:0030901350.024
negative regulation of protein phosphorylationGO:00019331260.024
immune effector processGO:00022523210.024
Fly
regulation of synaptic growth at neuromuscular junctionGO:000858240.023
negative regulation of phosphorus metabolic processGO:00105631840.023
skeletal muscle organ developmentGO:00605381630.023
axon target recognitionGO:000741240.023
regulation of sequence specific dna binding transcription factor activityGO:00510901060.023
rhythmic processGO:00485111740.023
regulation of establishment of protein localizationGO:00702011810.023
regulation of nucleotide catabolic processGO:00308111220.023
response to radiationGO:00093141650.023
regulation of histone methylationGO:0031060300.023
mitotic cell cycleGO:00002781950.023
learning or memoryGO:00076111480.023
organophosphate catabolic processGO:00464342320.023
appendage morphogenesisGO:00351071490.023
protein catabolic processGO:00301632210.022
Yeast Fly
intracellular receptor signaling pathwayGO:0030522740.022
ribonucleoside metabolic processGO:00091192450.022
regulation of cellular catabolic processGO:00313292420.022
Fly
response to oxidative stressGO:00069791230.022
response to decreased oxygen levelsGO:0036293590.022
stem cell developmentGO:00488642190.022
neural tube formationGO:00018411080.022
telencephalon developmentGO:00215371860.022
myeloid cell differentiationGO:00300992330.022
regulation of kinase activityGO:00435492490.022
regulation of purine nucleotide catabolic processGO:00331211220.022
morphogenesis of embryonic epitheliumGO:00163311590.022
purine nucleotide catabolic processGO:00061952110.022
negative regulation of cytokine productionGO:0001818840.021
regulation of chromosome organizationGO:0033044830.021
mitochondrion organizationGO:00070051340.021
rho protein signal transductionGO:0007266320.021
ribonucleotide catabolic processGO:00092612080.021
intrinsic apoptotic signaling pathwayGO:00971931320.021
histone deubiquitinationGO:001657820.020
purine nucleoside metabolic processGO:00422782410.020
ossificationGO:00015032160.020
chromatin remodelingGO:0006338320.020
regulation of cellular amino acid metabolic processGO:000652150.020
regulation of ossificationGO:00302781120.020
protein acylationGO:0043543640.020
cellular component assembly involved in morphogenesisGO:00109271390.020
rna interferenceGO:001624620.020
regulation of organelle organizationGO:00330432890.020
glycosyl compound catabolic processGO:19016582060.020
response to oxygen levelsGO:0070482620.020
meiotic nuclear divisionGO:00071261150.019
locomotory behaviorGO:00076261950.019
multicellular organism growthGO:00352641610.019
regulation of neuron differentiationGO:00456642810.019
negative regulation of cellular amine metabolic processGO:003323910.019
nuclear importGO:0051170950.019
cellular response to organonitrogen compoundGO:00714171450.019
leukocyte homeostasisGO:0001776790.019
regionalizationGO:00030023370.019
cognitionGO:00508901490.019
regulation of chromatin modificationGO:1903308570.019
negative regulation of protein modification processGO:00314001630.019
proteasomal protein catabolic processGO:0010498980.019
Fly
negative regulation of cell developmentGO:00107211690.018
negative regulation of synapse assemblyGO:005196430.018
ameboidal type cell migrationGO:00016671280.018
cellular response to oxidative stressGO:0034599760.018
lymphocyte differentiationGO:00300982420.018
regulation of cellular amine metabolic processGO:0033238200.018
regulation of osteoblast differentiationGO:0045667670.018
response to lipopolysaccharideGO:00324961280.018
dna repairGO:00062811070.018
regulation of protein serine threonine kinase activityGO:00719001570.018
amine metabolic processGO:0009308450.018
regulation of histone modificationGO:0031056560.018
regulation of chromatin organizationGO:1902275570.018
developmental growth involved in morphogenesisGO:00605601380.018
regulation of multi organism processGO:00439001110.018
Fly
rna processingGO:00063961050.018
negative regulation of phosphorylationGO:00423261660.018
single organism nuclear importGO:1902593950.018
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.018
positive regulation of organelle organizationGO:00106381280.017
embryonic organ morphogenesisGO:00485622760.017
palate developmentGO:0060021760.017
regulation of anatomical structure sizeGO:00900661780.017
protein homotrimerizationGO:007020740.017
regulation of defense response to bacteriumGO:190042430.017
Fly
regulation of mapk cascadeGO:00434082480.017
mammary gland epithelium developmentGO:0061180650.017
embryonic skeletal system developmentGO:00487061200.017
striated muscle tissue developmentGO:00147062930.017
translationGO:0006412930.017
negative regulation of transferase activityGO:0051348850.017
regulation of cellular protein catabolic processGO:1903362610.017
Fly
cellular response to growth factor stimulusGO:00713631970.016
appendage developmentGO:00487361660.016
peptide secretionGO:00027901140.016
angiogenesisGO:00015252010.016
regulation of cell motilityGO:20001452360.016
fertilizationGO:00095661270.016
regulation of endopeptidase activityGO:0052548890.016
myeloid leukocyte differentiationGO:00025731190.016
response to insulinGO:00328681000.016
demethylationGO:0070988230.016
tissue homeostasisGO:00018941150.015
microtubule based processGO:00070172360.015
regulation of angiogenesisGO:0045765810.015
regulation of protein bindingGO:0043393600.015
epithelial cell proliferationGO:00506731740.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
negative regulation of growthGO:0045926990.015
stem cell maintenanceGO:00198271300.015
regulation of cysteine type endopeptidase activityGO:2000116650.015
cell cycle checkpointGO:0000075470.015
nuclear transportGO:00511691390.015
positive regulation of purine nucleotide catabolic processGO:0033123880.015
regulation of membrane potentialGO:00423911920.015
positive regulation of dna templated transcription elongationGO:003278620.015
canonical wnt signaling pathwayGO:00600701300.015
sensory perceptionGO:00076002450.015
nucleocytoplasmic transportGO:00069131390.015
microtubule cytoskeleton organizationGO:00002261570.014
positive regulation of cellular catabolic processGO:00313311480.014
Fly
cellular response to misfolded proteinGO:007121850.014
pallium developmentGO:00215431200.014
response to peptideGO:19016521360.014
negative regulation of apoptotic signaling pathwayGO:20012341040.014
cellular response to insulin stimulusGO:0032869780.014
positive regulation of protein modification processGO:00314012990.014
proteolysis involved in cellular protein catabolic processGO:00516031470.014
Yeast Fly
multicellular organismal homeostasisGO:00488711640.014
regulation of cellular response to stressGO:00801351590.014
dna methylationGO:0006306430.014
negative regulation of dna replicationGO:000815640.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
regulation of nucleoside metabolic processGO:00091181300.014
regulation of mitotic cell cycleGO:00073461260.014
nucleotide metabolic processGO:00091173320.014
regulation of myeloid cell differentiationGO:0045637960.014
regulation of g1 s transition of mitotic cell cycleGO:2000045350.014
anatomical structure homeostasisGO:00602491450.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.014
transmission of nerve impulseGO:0019226760.014
regulation of ras protein signal transductionGO:00465781140.014
meiosis iGO:0007127600.014
leukocyte differentiationGO:00025213420.014
protein import into nucleusGO:0006606950.013
multicellular organismal response to stressGO:0033555620.013
regulation of stem cell proliferationGO:0072091780.013
limb developmentGO:00601731660.013
cation homeostasisGO:00550802120.013
rna splicingGO:0008380540.013
muscle cell differentiationGO:00426922610.013
spermatid differentiationGO:00485151150.013
regulation of neural precursor cell proliferationGO:2000177700.013
development of primary sexual characteristicsGO:00451371430.013
negative regulation of cell cycleGO:00457861230.013
peptidyl lysine methylationGO:0018022290.013
nitrogen compound transportGO:00717052710.013
hematopoietic progenitor cell differentiationGO:00022441430.013
antimicrobial peptide productionGO:000277520.013
Fly
response to light stimulusGO:00094161350.013
regulation of cytoskeleton organizationGO:00514931220.013
dendrite developmentGO:00163581150.013
regulation of protein kinase b signalingGO:0051896560.013
histone lysine demethylationGO:0070076130.013
neural tube closureGO:0001843900.013
membrane organizationGO:00610242450.013
Yeast
regulation of epithelial cell proliferationGO:00506781410.013
positive regulation of protein catabolic processGO:0045732600.013
Fly
protein oligomerizationGO:0051259670.013
adult behaviorGO:00305341350.013
positive regulation of gtpase activityGO:0043547850.013
placenta developmentGO:00018901400.013
positive regulation of cellular amine metabolic processGO:003324050.013
regulation of vasculature developmentGO:1901342880.013
muscle tissue developmentGO:00605373080.013
positive regulation of defense responseGO:00313491240.013
wnt signaling pathwayGO:00160551880.013
single fertilizationGO:0007338820.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.012
Fly
regulation of antimicrobial peptide biosynthetic processGO:000280510.012
response to heatGO:0009408270.012
regulation of protein transportGO:00512231630.012
negative regulation of cellular component organizationGO:00511291940.012
epithelial tube morphogenesisGO:00605623030.012
negative regulation of immune system processGO:00026832090.012
Fly
cellular response to acid chemicalGO:0071229680.012
regulation of nucleotide metabolic processGO:00061401690.012
regulation of cellular component sizeGO:00325351210.012
regulation of dna replicationGO:0006275170.012
Yeast
histone acetylationGO:0016573410.012
response to sterolGO:003631440.012
cytoplasmic transportGO:00164822340.012
metal ion homeostasisGO:00550651890.012
amide transportGO:00428861380.012
cellular homeostasisGO:00197252400.012
Yeast
synaptic vesicle localizationGO:0097479590.012
regulation of asymmetric cell divisionGO:000978640.012
positive regulation of peptidase activityGO:0010952490.012
atp metabolic processGO:0046034750.012
positive regulation of protein transportGO:0051222930.012
metencephalon developmentGO:0022037890.012
purine ribonucleoside metabolic processGO:00461282410.012
glucose homeostasisGO:00425931280.012
response to growth factorGO:00708481980.012
regulation of translationGO:0006417710.012
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.012
regulation of hormone levelsGO:00108172110.012
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.012
interleukin 8 productionGO:003263740.012
protein processingGO:00164851630.012
response to retinoic acidGO:0032526560.012
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.012
actin polymerization or depolymerizationGO:0008154540.012
memoryGO:0007613580.011
regulation of intracellular transportGO:00323861590.011
response to hypoxiaGO:0001666580.011
stem cell differentiationGO:00488632680.011
attachment of spindle microtubules to kinetochoreGO:000860840.011
regulation of peptidase activityGO:0052547960.011
dna replicationGO:0006260520.011
Yeast
cation transportGO:00068123990.011
organophosphate biosynthetic processGO:00904071220.011
cellular response to peptide hormone stimulusGO:0071375920.011
defense response to bacteriumGO:00427421190.011
Fly
protein dna complex disassemblyGO:003298610.011
cellular response to organic cyclic compoundGO:0071407870.011
germ cell developmentGO:00072811850.011
regulation of myeloid leukocyte differentiationGO:0002761580.011
mitotic g1 dna damage checkpointGO:003157140.011
protein secretionGO:00093061110.011
multicellular organismal signalingGO:0035637910.011
positive regulation of protein phosphorylationGO:00019342420.011
cellular response to cytokine stimulusGO:00713451890.011
glial cell differentiationGO:00100011310.011
cellular amide metabolic processGO:0043603580.011
regulation of protein catabolic processGO:00421761080.011
Fly
carbohydrate homeostasisGO:00335001280.011
establishment of protein localization to organelleGO:00725941180.011
positive regulation of apoptotic signaling pathwayGO:2001235950.011
response to temperature stimulusGO:0009266550.011
negative regulation of protein serine threonine kinase activityGO:0071901490.011
regulation of response to dna damage stimulusGO:2001020340.011
sequestering of metal ionGO:0051238190.011
regulation of cell projection organizationGO:00313442060.011
ras protein signal transductionGO:0007265770.011
Mouse
muscle cell developmentGO:00550011330.011
regulation of leukocyte differentiationGO:19021051590.010
positive regulation of synaptic plasticityGO:003191540.010
transcription factor import into nucleusGO:0042991260.010
regulation of protein stabilityGO:0031647520.010
positive regulation of mapk cascadeGO:00434101700.010
response to transforming growth factor betaGO:0071559880.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.010
peroxisomal transportGO:004357440.010
mrna metabolic processGO:0016071840.010
cell type specific apoptotic processGO:00972852680.010
response to topologically incorrect proteinGO:0035966250.010
protein modification by small protein conjugationGO:00324461870.010
chemotaxisGO:00069352470.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
spermatid developmentGO:00072861080.010
neural retina developmentGO:0003407410.010
negative regulation of multi organism processGO:0043901680.010
Fly
regulation of system processGO:00440572000.010
sensory organ morphogenesisGO:00905962420.010

Usp21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
eye and adnexa diseaseDOID:149200.017
retinal diseaseDOID:567900.017
eye diseaseDOID:561400.017
sensory system diseaseDOID:005015500.017
retinal degenerationDOID:846600.017