Mus musculus

31 known processes

Fbxw8

F-box and WD-40 domain protein 8

(Aliases: FBW8,FBXO29,4930438M06Rik,Fbx29,FBW6)

Fbxw8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ras protein signal transductionGO:0007265770.147
cellular amino acid metabolic processGO:00065201030.091
small gtpase mediated signal transductionGO:0007264970.082
protein catabolic processGO:00301632210.079
actin cytoskeleton organizationGO:00300362200.057
nucleoside phosphate metabolic processGO:00067533380.056
endomembrane system organizationGO:00102561470.054
Human
nucleobase containing small molecule metabolic processGO:00550863520.053
cellular amine metabolic processGO:0044106440.052
protein modification by small protein conjugationGO:00324461870.051
Human
negative regulation of cellular protein metabolic processGO:00322692470.051
cellular response to organonitrogen compoundGO:00714171450.049
cell adhesionGO:00071553290.048
nucleotide metabolic processGO:00091173320.048
modification dependent protein catabolic processGO:00199411330.045
wnt signaling pathwayGO:00160551880.045
male gamete generationGO:00482322850.045
purine ribonucleoside triphosphate catabolic processGO:00092071990.045
rho protein signal transductionGO:0007266320.044
regulation of proteolysisGO:00301621640.042
regulation of defense responseGO:00313472330.041
nucleoside triphosphate metabolic processGO:00091412300.041
regulation of cellular ketone metabolic processGO:0010565660.040
macromolecule catabolic processGO:00090572810.040
purine nucleoside metabolic processGO:00422782410.040
cytoplasmic transportGO:00164822340.040
positive regulation of programmed cell deathGO:00430682180.039
cellular protein catabolic processGO:00442571550.039
oxidation reduction processGO:00551143420.039
protein localization to membraneGO:00726571080.039
positive regulation of protein modification processGO:00314012990.038
regulation of cell motilityGO:20001452360.038
purine containing compound metabolic processGO:00725213110.038
apoptotic signaling pathwayGO:00971903060.037
cation transportGO:00068123990.037
regulation of cell migrationGO:00303342190.037
purine nucleoside catabolic processGO:00061522050.037
mapk cascadeGO:00001652810.037
positive regulation of protein phosphorylationGO:00019342420.036
plasma membrane organizationGO:0007009900.036
glycosyl compound catabolic processGO:19016582060.035
protein maturationGO:00516041760.035
purine nucleotide metabolic processGO:00061633020.035
purine ribonucleotide metabolic processGO:00091502900.034
response to organonitrogen compoundGO:00102432460.034
negative regulation of protein metabolic processGO:00512482820.034
purine ribonucleotide catabolic processGO:00091542080.034
proteolysis involved in cellular protein catabolic processGO:00516031470.033
immune effector processGO:00022523210.033
positive regulation of cell deathGO:00109422240.033
protein ubiquitinationGO:00165671710.033
Human
transmembrane transportGO:00550854120.033
ribonucleotide metabolic processGO:00092592910.033
purine nucleoside triphosphate catabolic processGO:00091462030.032
protein localization to organelleGO:00333651850.032
purine ribonucleoside triphosphate metabolic processGO:00092052200.032
regulation of response to woundingGO:19030341890.032
positive regulation of apoptotic processGO:00430652170.031
positive regulation of protein kinase activityGO:00458601440.031
aromatic compound catabolic processGO:00194392860.031
protein processingGO:00164851630.031
nucleoside catabolic processGO:00091642060.031
regulation of cellular amino acid metabolic processGO:000652150.030
posttranscriptional regulation of gene expressionGO:00106081550.029
ossificationGO:00015032160.029
cellular ketone metabolic processGO:0042180840.029
inflammatory responseGO:00069542440.029
negative regulation of cellular amino acid metabolic processGO:004576300.028
protein modification by small protein conjugation or removalGO:00706472070.028
Human
regulation of hydrolase activityGO:00513362460.028
maintenance of locationGO:0051235890.028
membrane organizationGO:00610242450.027
lipid localizationGO:00108761260.027
muscle cell differentiationGO:00426922610.027
cellular nitrogen compound catabolic processGO:00442702800.027
cell type specific apoptotic processGO:00972852680.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.026
blood vessel morphogenesisGO:00485142850.026
response to peptide hormoneGO:00434341270.026
regulation of mapk cascadeGO:00434082480.025
proteasomal protein catabolic processGO:0010498980.025
purine containing compound catabolic processGO:00725232130.025
regulation of intracellular transportGO:00323861590.025
negative regulation of phosphorus metabolic processGO:00105631840.025
negative regulation of molecular functionGO:00440922580.025
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.025
negative regulation of protein modification processGO:00314001630.025
ubiquitin dependent protein catabolic processGO:00065111290.024
peptidyl amino acid modificationGO:00181933360.024
ribose phosphate metabolic processGO:00196932910.024
nuclear divisionGO:00002801580.024
lipid transportGO:0006869980.024
regulation of cellular amine metabolic processGO:0033238200.023
ribonucleoside triphosphate metabolic processGO:00091992200.023
negative regulation of cellular amine metabolic processGO:003323910.023
modification dependent macromolecule catabolic processGO:00436321330.023
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.023
purine ribonucleoside metabolic processGO:00461282410.023
organelle fissionGO:00482851700.023
carboxylic acid transportGO:00469421000.023
spermatogenesisGO:00072832840.023
organelle assemblyGO:00709251770.023
organic cyclic compound catabolic processGO:19013612950.022
endocytosisGO:00068971680.022
actin filament organizationGO:00070151130.022
regulation of neuron differentiationGO:00456642810.022
Human
carbohydrate metabolic processGO:00059752300.022
nucleoside phosphate catabolic processGO:19012922220.022
regulation of secretion by cellGO:19035302490.022
negative regulation of intracellular signal transductionGO:19025321670.022
microtubule based processGO:00070172360.022
cytokine productionGO:00018163190.022
nucleoside metabolic processGO:00091162460.021
cellularizationGO:000734910.021
purine nucleotide catabolic processGO:00061952110.021
ameboidal type cell migrationGO:00016671280.021
ribonucleoside metabolic processGO:00091192450.021
negative regulation of proteolysisGO:0045861740.021
regulation of protein localizationGO:00328802310.021
mitotic cell cycleGO:00002781950.021
purine ribonucleoside catabolic processGO:00461302050.021
blood circulationGO:00080151950.021
carbohydrate derivative catabolic processGO:19011362310.021
regulation of protein serine threonine kinase activityGO:00719001570.021
ribonucleoside catabolic processGO:00424542060.020
circulatory system processGO:00030131970.020
positive regulation of nervous system developmentGO:00519622210.020
Human
anion transportGO:00068201770.020
cellular response to hormone stimulusGO:00328701500.020
skin developmentGO:00435882200.020
response to growth factorGO:00708481980.020
organonitrogen compound catabolic processGO:19015652640.020
regulation of establishment of protein localizationGO:00702011810.020
lung developmentGO:00303241640.020
positive regulation of defense responseGO:00313491240.020
regulation of cytokine productionGO:00018172660.019
cellular carbohydrate metabolic processGO:00442621190.019
regulation of transferase activityGO:00513382630.019
ribonucleotide catabolic processGO:00092612080.019
heterocycle catabolic processGO:00467002800.019
regulation of apoptotic signaling pathwayGO:20012331970.019
regulation of protein maturationGO:1903317960.019
metal ion homeostasisGO:00550651890.019
cellular response to growth factor stimulusGO:00713631970.019
intracellular protein transportGO:00068862040.019
positive regulation of transferase activityGO:00513471670.019
spermatid differentiationGO:00485151150.019
peptidyl serine modificationGO:0018209830.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
regulation of protein processingGO:0070613960.019
positive regulation of cell projection organizationGO:0031346950.019
Human
negative regulation of phosphate metabolic processGO:00459361840.018
response to radiationGO:00093141650.018
establishment of protein localization to organelleGO:00725941180.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
amine metabolic processGO:0009308450.018
cellular macromolecule catabolic processGO:00442652060.018
positive regulation of kinase activityGO:00336741550.018
organophosphate catabolic processGO:00464342320.018
guanosine containing compound metabolic processGO:19010681440.018
regulation of membrane potentialGO:00423911920.018
negative regulation of protein maturationGO:1903318790.018
development of primary sexual characteristicsGO:00451371430.018
wound healingGO:00420601570.018
positive regulation of cellular amine metabolic processGO:003324050.018
organic anion transportGO:00157111370.018
regulation of canonical wnt signaling pathwayGO:0060828820.018
cellular response to abiotic stimulusGO:0071214560.018
regulation of anatomical structure sizeGO:00900661780.018
negative regulation of protein processingGO:0010955790.018
mitochondrion organizationGO:00070051340.018
regulation of lymphocyte activationGO:00512492400.017
germ cell developmentGO:00072811850.017
regulation of kinase activityGO:00435492490.017
organic acid transportGO:00158491010.017
nucleotide catabolic processGO:00091662170.017
single organism cell adhesionGO:00986021560.017
protein localization to nucleusGO:00345041210.017
regulation of actin filament based processGO:0032970990.017
cellular homeostasisGO:00197252400.017
regulation of cell activationGO:00508652890.017
mrna metabolic processGO:0016071840.017
spermatid developmentGO:00072861080.017
regulation of protein kinase activityGO:00458592320.017
mrna processingGO:0006397630.017
negative regulation of apoptotic signaling pathwayGO:20012341040.017
negative regulation of synapse assemblyGO:005196430.017
regulation of secretionGO:00510462740.016
positive regulation of cytokine productionGO:00018191740.016
skeletal system morphogenesisGO:00487052030.016
ribonucleoside triphosphate catabolic processGO:00092031990.016
regulation of hormone levelsGO:00108172110.016
respiratory tube developmentGO:00303231670.016
multicellular organismal signalingGO:0035637910.016
meiotic cell cycleGO:00513211220.016
respiratory system developmentGO:00605411900.016
regulation of protein stabilityGO:0031647520.016
regulation of ral protein signal transductionGO:003248540.016
synaptic transmissionGO:00072683290.016
interleukin 5 secretionGO:007260320.016
g protein coupled receptor signaling pathwayGO:00071862430.016
regulation of nucleoside metabolic processGO:00091181300.016
regulation of protein transportGO:00512231630.015
response to lipopolysaccharideGO:00324961280.015
positive regulation of secretionGO:00510471300.015
positive regulation of protein serine threonine kinase activityGO:00719021060.015
regulation of cell cycleGO:00517262810.015
gtp metabolic processGO:00460391440.015
amide transportGO:00428861380.015
epithelial cell developmentGO:00020641590.015
peptidyl serine phosphorylationGO:0018105740.015
developmental maturationGO:00217001930.015
regulation of cysteine type endopeptidase activityGO:2000116650.015
response to light stimulusGO:00094161350.015
regulation of cell adhesionGO:00301551540.015
regulation of ossificationGO:00302781120.015
regulation of organelle organizationGO:00330432890.015
molting cycleGO:0042303900.015
calcium ion homeostasisGO:00550741270.015
positive regulation of cell motilityGO:20001471160.015
cellular response to peptideGO:1901653920.015
negative regulation of transferase activityGO:0051348850.014
regulation of homeostatic processGO:00328441820.014
stress activated mapk cascadeGO:0051403800.014
leukocyte mediated immunityGO:00024431740.014
regulation of body fluid levelsGO:00508781620.014
cellular response to lipidGO:00713961450.014
bone developmentGO:00603481200.014
stem cell differentiationGO:00488632680.014
nucleocytoplasmic transportGO:00069131390.014
cellular component assembly involved in morphogenesisGO:00109271390.014
multicellular organismal homeostasisGO:00488711640.014
cell growthGO:00160491300.014
single organism nuclear importGO:1902593950.014
lipid biosynthetic processGO:00086101790.014
carbohydrate homeostasisGO:00335001280.014
rna processingGO:00063961050.014
transmission of nerve impulseGO:0019226760.014
locomotory behaviorGO:00076261950.014
neuronal action potentialGO:0019228540.014
positive regulation of mapk cascadeGO:00434101700.014
regulation of protein catabolic processGO:00421761080.014
regulation of system processGO:00440572000.014
organonitrogen compound biosynthetic processGO:19015661920.014
regulation of endopeptidase activityGO:0052548890.014
regulation of peptidase activityGO:0052547960.014
intrinsic apoptotic signaling pathwayGO:00971931320.013
carbohydrate biosynthetic processGO:0016051740.013
vesicle localizationGO:0051648860.013
monocarboxylic acid metabolic processGO:00327871910.013
regulation of nucleotide catabolic processGO:00308111220.013
single organismal cell cell adhesionGO:00163371310.013
chromatin organizationGO:00063252060.013
response to oxidative stressGO:00069791230.013
cholesterol storageGO:001087840.013
negative regulation of phosphorylationGO:00423261660.013
protein importGO:00170381010.013
negative regulation of cellular component organizationGO:00511291940.013
mitotic cell cycle processGO:19030471590.013
regulation of fatty acid beta oxidationGO:003199810.013
carbohydrate derivative biosynthetic processGO:19011371830.013
insulin receptor signaling pathwayGO:0008286490.013
regulation of interleukin 13 secretionGO:200066520.013
glycerolipid metabolic processGO:00464861220.013
positive regulation of organelle organizationGO:00106381280.013
cellular response to peptide hormone stimulusGO:0071375920.013
regulation of mitochondrion organizationGO:0010821270.013
glucose metabolic processGO:0006006920.013
nitrogen compound transportGO:00717052710.013
regulation of purine nucleotide metabolic processGO:19005421690.013
t cell activationGO:00421102890.013
hexose metabolic processGO:0019318980.013
leukocyte activation involved in immune responseGO:00023661260.012
multicellular organism growthGO:00352641610.012
regulation of inflammatory responseGO:00507271470.012
protein localization to plasma membraneGO:0072659570.012
dna repairGO:00062811070.012
response to oxygen levelsGO:0070482620.012
positive regulation of hydrolase activityGO:00513451480.012
chemotaxisGO:00069352470.012
regulation of wnt signaling pathwayGO:00301111230.012
divalent inorganic cation homeostasisGO:00725071380.012
regulation of protein secretionGO:0050708820.012
guanosine containing compound catabolic processGO:19010691440.012
protein targetingGO:00066051430.012
cd4 positive alpha beta t cell cytokine productionGO:003574340.012
tissue homeostasisGO:00018941150.012
protein secretionGO:00093061110.012
coagulationGO:0050817780.012
cellular response to cytokine stimulusGO:00713451890.012
positive regulation of neuron projection regenerationGO:007057220.012
negative regulation of protein phosphorylationGO:00019331260.012
positive regulation of nucleotide metabolic processGO:00459811140.012
glucose homeostasisGO:00425931280.012
regulation of leukocyte differentiationGO:19021051590.012
nuclear transportGO:00511691390.012
regulation of cell shapeGO:0008360390.012
nucleoside triphosphate catabolic processGO:00091432050.012
regulation of protein targetingGO:1903533610.012
myotube differentiationGO:00149021050.012
cellular chemical homeostasisGO:00550822150.012
cellular modified amino acid metabolic processGO:0006575630.012
regulation of cytoplasmic transportGO:19036491120.012
platelet activationGO:0030168400.012
regulation of leukocyte mediated immunityGO:00027031040.012
positive regulation of intracellular transportGO:0032388700.012
atp metabolic processGO:0046034750.012
negative regulation of kinase activityGO:0033673810.012
dna metabolic processGO:00062593030.012
circadian rhythmGO:00076231140.012
reactive nitrogen species metabolic processGO:200105700.012
regulation of cellular catabolic processGO:00313292420.012
lymphocyte differentiationGO:00300982420.011
lateral inhibitionGO:004633110.011
sensory perceptionGO:00076002450.011
sequestering of calcium ionGO:0051208180.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.011
muscle tissue developmentGO:00605373080.011
gtp catabolic processGO:00061841430.011
immune response regulating signaling pathwayGO:00027641250.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
stress activated protein kinase signaling cascadeGO:0031098810.011
b cell activationGO:00421131610.011
cell fate commitmentGO:00451652100.011
positive regulation of cell activationGO:00508671580.011
regulation of mitotic cell cycle phase transitionGO:1901990730.011
response to uvGO:0009411440.011
g1 s transition of mitotic cell cycleGO:0000082570.011
glycoprotein metabolic processGO:00091001160.011
nucleoside monophosphate catabolic processGO:0009125590.011
myeloid leukocyte differentiationGO:00025731190.011
response to peptideGO:19016521360.011
action potentialGO:0001508780.011
cation transmembrane transportGO:00986552660.011
regulation of cellular component biogenesisGO:00440871810.011
cellular response to dna damage stimulusGO:00069742070.011
glycosyl compound metabolic processGO:19016572460.011
camera type eye developmentGO:00430102660.011
cellular ion homeostasisGO:00068731650.011
dephosphorylationGO:00163111290.011
glucose transportGO:0015758560.011
regulation of cell sizeGO:0008361720.011
syncytium formation by plasma membrane fusionGO:0000768420.011
methylationGO:00322591340.011
leukocyte differentiationGO:00025213420.011
peptide transportGO:00158331330.011
epidermis developmentGO:00085441870.011
regulation of mrna processingGO:0050684410.011
positive regulation of map kinase activityGO:0043406840.011
production of molecular mediator of immune responseGO:00024401030.011
response to acid chemicalGO:00011011110.011
cell substrate adhesionGO:00315891300.011
negative regulation of peptidase activityGO:0010466460.011
regulation of cell cycle processGO:00105641600.011
asymmetric stem cell divisionGO:009872230.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
neuron apoptotic processGO:00514021420.011
microtubule cytoskeleton organizationGO:00002261570.010
regulation of cell cycle phase transitionGO:1901987770.010
regulation of cell projection organizationGO:00313442060.010
Human
renal system developmentGO:00720012250.010
cellular response to organic cyclic compoundGO:0071407870.010
regulation of glucose metabolic processGO:0010906600.010
positive regulation of cell developmentGO:00107202370.010
Human
meiosis iGO:0007127600.010
cation homeostasisGO:00550802120.010
gonad developmentGO:00084061410.010
peptide secretionGO:00027901140.010
protein import into nucleusGO:0006606950.010
anion transmembrane transportGO:0098656710.010
response to inorganic substanceGO:0010035960.010
positive regulation of immune effector processGO:00026991070.010

Fbxw8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.017
neuromuscular diseaseDOID:44000.017
neuropathyDOID:87000.017
disease of anatomical entityDOID:700.017
charcot marie tooth diseaseDOID:1059500.017
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
sensory system diseaseDOID:005015500.012
musculoskeletal system diseaseDOID:1700.010