Mus musculus

49 known processes

Cul1

cullin 1

Cul1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugation or removalGO:00706472070.909
modification dependent macromolecule catabolic processGO:00436321330.536
cellular protein catabolic processGO:00442571550.415
regulation of protein stabilityGO:0031647520.397
protein modification by small protein conjugationGO:00324461870.285
proteasomal protein catabolic processGO:0010498980.261
proteolysis involved in cellular protein catabolic processGO:00516031470.248
mitotic cell cycle processGO:19030471590.226
Worm Fly
cellular macromolecule catabolic processGO:00442652060.223
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.215
response to light stimulusGO:00094161350.195
cellular response to dna damage stimulusGO:00069742070.192
Fly
stem cell developmentGO:00488642190.164
ribonucleoside triphosphate catabolic processGO:00092031990.126
purine ribonucleoside triphosphate metabolic processGO:00092052200.125
myosin filament organizationGO:003103330.124
positive regulation of protein complex assemblyGO:0031334450.118
ubiquitin dependent protein catabolic processGO:00065111290.115
nucleotide metabolic processGO:00091173320.109
nucleoside triphosphate catabolic processGO:00091432050.101
ribonucleoside catabolic processGO:00424542060.101
protein localization to organelleGO:00333651850.098
dna metabolic processGO:00062593030.097
guanosine containing compound metabolic processGO:19010681440.094
purine ribonucleotide metabolic processGO:00091502900.094
cell divisionGO:00513011200.089
myosin filament assemblyGO:003103420.089
establishment of protein localization to organelleGO:00725941180.089
nucleoside catabolic processGO:00091642060.089
carbohydrate derivative catabolic processGO:19011362310.089
purine nucleoside triphosphate metabolic processGO:00091442260.087
protein targetingGO:00066051430.085
membrane organizationGO:00610242450.083
glycosyl compound catabolic processGO:19016582060.082
regulation of protein localizationGO:00328802310.080
nucleoside phosphate metabolic processGO:00067533380.078
striated muscle myosin thick filament assemblyGO:007168810.077
cytoplasmic transportGO:00164822340.077
nucleoside metabolic processGO:00091162460.075
cellular ketone metabolic processGO:0042180840.072
purine ribonucleoside catabolic processGO:00461302050.068
protein importGO:00170381010.067
negative regulation of protein metabolic processGO:00512482820.067
nucleoside triphosphate metabolic processGO:00091412300.059
macromolecule catabolic processGO:00090572810.058
cellular nitrogen compound catabolic processGO:00442702800.058
organelle assemblyGO:00709251770.057
peptidyl amino acid modificationGO:00181933360.055
nucleoside phosphate catabolic processGO:19012922220.053
heterocycle catabolic processGO:00467002800.052
negative regulation of dna replicationGO:000815640.052
ribonucleotide metabolic processGO:00092592910.051
protein ubiquitinationGO:00165671710.051
protein catabolic processGO:00301632210.049
ribose phosphate metabolic processGO:00196932910.048
apoptotic signaling pathwayGO:00971903060.048
small gtpase mediated signal transductionGO:0007264970.047
mitotic cell cycleGO:00002781950.046
Worm Fly
positive regulation of cellular catabolic processGO:00313311480.046
regulation of ras gtpase activityGO:0032318880.045
cellular amino acid metabolic processGO:00065201030.045
intracellular protein transportGO:00068862040.043
posttranscriptional regulation of gene expressionGO:00106081550.042
purine ribonucleotide catabolic processGO:00091542080.042
organonitrogen compound catabolic processGO:19015652640.041
regulation of cellular amino acid metabolic processGO:000652150.041
stem cell differentiationGO:00488632680.040
regulation of kinase activityGO:00435492490.040
organophosphate catabolic processGO:00464342320.040
purine nucleoside metabolic processGO:00422782410.039
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:0031146100.039
regulation of protein complex assemblyGO:0043254830.038
positive regulation of hydrolase activityGO:00513451480.038
aromatic compound catabolic processGO:00194392860.038
purine nucleoside catabolic processGO:00061522050.038
ras protein signal transductionGO:0007265770.037
regulation of organelle organizationGO:00330432890.037
regulation of transcription factor import into nucleusGO:0042990240.036
gonad developmentGO:00084061410.036
Worm
purine nucleotide catabolic processGO:00061952110.036
rna splicingGO:0008380540.035
positive regulation of proteolysisGO:0045862850.035
gtp metabolic processGO:00460391440.035
purine ribonucleoside triphosphate catabolic processGO:00092071990.034
ribonucleoside triphosphate metabolic processGO:00091992200.034
positive regulation of nucleotide catabolic processGO:0030813880.034
rna processingGO:00063961050.034
actomyosin structure organizationGO:0031032560.034
purine nucleoside triphosphate catabolic processGO:00091462030.034
muscle cell differentiationGO:00426922610.033
regulation of hydrolase activityGO:00513362460.033
cell fate commitmentGO:00451652100.032
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.032
blood vessel morphogenesisGO:00485142850.032
purine nucleotide metabolic processGO:00061633020.032
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.031
male gamete generationGO:00482322850.031
ribonucleotide catabolic processGO:00092612080.031
regulation of protein catabolic processGO:00421761080.031
covalent chromatin modificationGO:00165691630.030
cell adhesionGO:00071553290.030
regulation of cell motilityGO:20001452360.030
regulation of purine nucleotide catabolic processGO:00331211220.029
actin cytoskeleton organizationGO:00300362200.029
nuclear importGO:0051170950.029
regulation of response to dna damage stimulusGO:2001020340.029
purine containing compound catabolic processGO:00725232130.029
modification dependent protein catabolic processGO:00199411330.029
organelle fissionGO:00482851700.028
Worm
regulation of cellular ketone metabolic processGO:0010565660.028
purine containing compound metabolic processGO:00725213110.028
protein modification by small protein removalGO:0070646210.028
peptidyl serine phosphorylationGO:0018105740.027
positive regulation of purine nucleotide catabolic processGO:0033123880.027
nucleotide catabolic processGO:00091662170.026
microtubule based processGO:00070172360.026
synaptic transmissionGO:00072683290.026
single organism nuclear importGO:1902593950.026
regulation of protein targetingGO:1903533610.026
organic cyclic compound catabolic processGO:19013612950.026
negative regulation of cell proliferationGO:00082852960.025
Worm
cellular protein complex assemblyGO:00436231160.025
ribonucleoside metabolic processGO:00091192450.025
dna repairGO:00062811070.024
regulation of cell cycleGO:00517262810.024
Worm Fly
purine ribonucleoside metabolic processGO:00461282410.023
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.023
transmembrane transportGO:00550854120.023
establishment of organelle localizationGO:00516561220.023
regulation of cellular component biogenesisGO:00440871810.023
establishment or maintenance of cell polarityGO:0007163860.023
positive regulation of cell deathGO:00109422240.023
Worm
germ cell developmentGO:00072811850.022
nucleobase containing small molecule metabolic processGO:00550863520.022
response to radiationGO:00093141650.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
Fly
regulation of transmembrane transportGO:00347621280.022
cellular component assembly involved in morphogenesisGO:00109271390.022
methylationGO:00322591340.022
regulation of transferase activityGO:00513382630.022
regulation of nucleotide metabolic processGO:00061401690.022
dna endoreduplicationGO:004202340.021
skeletal muscle cell differentiationGO:0035914660.021
positive regulation of nucleoside metabolic processGO:0045979910.021
endomembrane system organizationGO:00102561470.021
cytokinesisGO:0000910170.021
epithelial tube morphogenesisGO:00605623030.021
negative regulation of cellular protein metabolic processGO:00322692470.020
regulation of cell migrationGO:00303342190.020
protein import into nucleusGO:0006606950.020
regulation of purine nucleotide metabolic processGO:19005421690.020
muscle tissue developmentGO:00605373080.020
negative regulation of triglyceride biosynthetic processGO:001086820.020
negative regulation of cell cycleGO:00457861230.019
Worm Fly
positive regulation of protein phosphorylationGO:00019342420.019
regulation of nucleotide catabolic processGO:00308111220.019
cellular amine metabolic processGO:0044106440.019
positive regulation of protein modification processGO:00314012990.018
guanosine containing compound catabolic processGO:19010691440.018
nucleocytoplasmic transportGO:00069131390.018
mesenchymal cell differentiationGO:00487621070.018
regulation of cellular response to growth factor stimulusGO:0090287820.018
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.018
lipid localizationGO:00108761260.018
organelle localizationGO:00516401790.018
protein sumoylationGO:0016925140.018
endocytosisGO:00068971680.018
Worm
epithelial cell proliferationGO:00506731740.017
amine metabolic processGO:0009308450.017
regulation of cellular catabolic processGO:00313292420.017
wound healingGO:00420601570.017
stem cell maintenanceGO:00198271300.017
regulation of mitotic cell cycleGO:00073461260.017
Worm Fly
positive regulation of ras gtpase activityGO:0032320650.017
regulation of histone modificationGO:0031056560.016
placenta developmentGO:00018901400.016
snrna metabolic processGO:001607310.016
adult behaviorGO:00305341350.016
protein stabilizationGO:0050821250.016
regulation of proteasomal protein catabolic processGO:0061136460.016
regulation of epithelial cell proliferationGO:00506781410.016
response to transforming growth factor betaGO:0071559880.016
protein localization to membraneGO:00726571080.016
regulation of mapk cascadeGO:00434082480.016
stem cell divisionGO:0017145300.015
mesenchyme developmentGO:00604851520.015
muscle cell developmentGO:00550011330.015
mesenchymal cell developmentGO:0014031930.015
rna splicing via transesterification reactionsGO:0000375430.015
negative regulation of cellular catabolic processGO:0031330470.015
regulation of cellular protein catabolic processGO:1903362610.015
regulation of ion transmembrane transportGO:00347651190.015
body morphogenesisGO:0010171450.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.015
chemotaxisGO:00069352470.015
actin mediated cell contractionGO:0070252150.015
regulation of protein processingGO:0070613960.014
positive regulation of cellular component biogenesisGO:0044089940.014
response to uvGO:0009411440.014
striated muscle cell developmentGO:00550021250.014
renal system developmentGO:00720012250.014
lateral inhibitionGO:004633110.014
atp metabolic processGO:0046034750.014
positive regulation of nucleotide metabolic processGO:00459811140.014
cellular response to peptide hormone stimulusGO:0071375920.014
Fly
regulation of cytoplasmic transportGO:19036491120.014
glycosyl compound metabolic processGO:19016572460.014
gene silencingGO:0016458380.014
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.014
spermatogenesisGO:00072832840.014
spermatid differentiationGO:00485151150.013
metaphase plate congressionGO:005131020.013
gland developmentGO:00487323300.013
negative regulation of protein maturationGO:1903318790.013
mitotic nuclear divisionGO:0007067480.013
Worm
sperm motilityGO:0030317470.013
regulation of protein localization to nucleusGO:1900180600.013
regulation of cellular component sizeGO:00325351210.013
Worm
dna replicationGO:0006260520.013
cellular response to transforming growth factor beta stimulusGO:0071560880.013
locomotory behaviorGO:00076261950.013
regulation of proteolysisGO:00301621640.013
positive regulation of transcription by galactoseGO:000041110.013
hematopoietic progenitor cell differentiationGO:00022441430.013
axonogenesisGO:00074092740.013
positive regulation of transferase activityGO:00513471670.013
negative regulation of cell developmentGO:00107211690.013
response to growth factorGO:00708481980.012
regulation of cell cycle processGO:00105641600.012
Fly
regulation of intracellular protein transportGO:0033157820.012
rho protein signal transductionGO:0007266320.012
t cell activationGO:00421102890.012
regulation of nucleocytoplasmic transportGO:0046822730.012
cell type specific apoptotic processGO:00972852680.012
neuron projection guidanceGO:00974851410.012
nuclear transportGO:00511691390.012
cell cycle checkpointGO:0000075470.012
Fly
cell growthGO:00160491300.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
microtubule cytoskeleton organizationGO:00002261570.012
positive regulation of gtp catabolic processGO:0033126850.012
digestive system developmentGO:00551232000.012
negative regulation of mitotic cell cycleGO:0045930580.012
Worm Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
intracellular receptor signaling pathwayGO:0030522740.012
epithelial to mesenchymal transitionGO:0001837470.012
dna recombinationGO:0006310920.012
response to organic cyclic compoundGO:00140701980.011
reproductive behaviorGO:0019098320.011
positive regulation of protein catabolic processGO:0045732600.011
mrna metabolic processGO:0016071840.011
blastocyst formationGO:0001825330.011
peptidyl serine modificationGO:0018209830.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
regulation of cellular response to stressGO:00801351590.011
gastrulationGO:00073691160.011
oocyte constructionGO:000730820.011
maternal determination of anterior posterior axis embryoGO:000835820.011
regulation of mitosisGO:0007088290.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
regulation of protein kinase activityGO:00458592320.011
b cell activationGO:00421131610.011
regulation of cellular amine metabolic processGO:0033238200.011
protein localization to nucleusGO:00345041210.011
regulation of bindingGO:00510981110.011
cellular response to growth factor stimulusGO:00713631970.011
mitotic cytokinesisGO:000028140.011
oocyte anterior posterior axis specificationGO:000731420.011
ion transmembrane transportGO:00342203610.011
synapse organizationGO:00508081250.010
carbohydrate derivative biosynthetic processGO:19011371830.010
molting cycleGO:0042303900.010
genitalia developmentGO:0048806370.010
negative regulation of intracellular signal transductionGO:19025321670.010
Fly
androgen receptor signaling pathwayGO:003052180.010
stem cell proliferationGO:00720891170.010
calcium ion transmembrane transportGO:0070588850.010

Cul1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.085
disease of anatomical entityDOID:700.085
muscular diseaseDOID:008000000.085
muscle tissue diseaseDOID:6600.064
myopathyDOID:42300.064
physical disorderDOID:008001500.043
nervous system diseaseDOID:86300.019
sensory system diseaseDOID:005015500.019
eye and adnexa diseaseDOID:149200.019
muscular dystrophyDOID:988400.016
eye diseaseDOID:561400.014