| cellular amino acid metabolic process | GO:0006520 | 103 | 0.113 | |
| intracellular protein transport | GO:0006886 | 204 | 0.067 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.061 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.055 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.055 | |
| amine metabolic process | GO:0009308 | 45 | 0.055 | |
| 4 hydroxyproline metabolic process | GO:0019471 | 5 | 0.050 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.049 | |
| dna metabolic process | GO:0006259 | 303 | 0.048 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.045 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.044 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.042 | |
| spermatogenesis | GO:0007283 | 284 | 0.042 | |
| immune effector process | GO:0002252 | 321 | 0.042 | |
| transmembrane transport | GO:0055085 | 412 | 0.041 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.040 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.040 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.040 | |
| membrane organization | GO:0061024 | 245 | 0.040 | |
| regulation of protein transport | GO:0051223 | 163 | 0.039 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.039 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 55 | 0.038 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.038 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.038 | |
| male gamete generation | GO:0048232 | 285 | 0.036 | |
| gland development | GO:0048732 | 330 | 0.036 | |
| amide transport | GO:0042886 | 138 | 0.035 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.034 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.034 | |
| regulation of system process | GO:0044057 | 200 | 0.034 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.033 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.033 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.033 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.033 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.032 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.032 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.031 | |
| single organism nuclear import | GO:1902593 | 95 | 0.031 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.031 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.029 | |
| endomembrane system organization | GO:0010256 | 147 | 0.029 | |
| protein targeting | GO:0006605 | 143 | 0.029 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.028 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.028 | |
| protein localization to organelle | GO:0033365 | 185 | 0.028 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.028 | |
| muscle system process | GO:0003012 | 141 | 0.027 | |
| extracellular structure organization | GO:0043062 | 148 | 0.027 | |
| regulation of protein localization | GO:0032880 | 231 | 0.027 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.027 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.027 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.026 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.026 | |
| oocyte construction | GO:0007308 | 2 | 0.025 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.025 | |
| protein maturation | GO:0051604 | 176 | 0.025 | |
| cellular response to lipid | GO:0071396 | 145 | 0.025 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.025 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.025 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.025 | |
| mapk cascade | GO:0000165 | 281 | 0.025 | |
| coagulation | GO:0050817 | 78 | 0.024 | |
| inflammatory response | GO:0006954 | 244 | 0.024 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.024 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.024 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.024 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.024 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.024 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.024 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.023 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.023 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.023 | |
| cellular homeostasis | GO:0019725 | 240 | 0.023 | |
| hemostasis | GO:0007599 | 78 | 0.023 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.023 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.023 | |
| nuclear import | GO:0051170 | 95 | 0.022 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.022 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.022 | |
| cell killing | GO:0001906 | 67 | 0.022 | |
| cation transport | GO:0006812 | 399 | 0.022 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.022 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.022 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.022 | |
| response to oxygen radical | GO:0000305 | 16 | 0.022 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.021 | |
| development of primary male sexual characteristics | GO:0046546 | 88 | 0.021 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.021 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.021 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.021 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.021 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.021 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.021 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.021 | |
| muscle tissue development | GO:0060537 | 308 | 0.021 | |
| protein import into nucleus | GO:0006606 | 95 | 0.021 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.021 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.021 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.020 | |
| nuclear transport | GO:0051169 | 139 | 0.020 | |
| wound healing | GO:0042060 | 157 | 0.020 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.020 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.020 | |
| peptide transport | GO:0015833 | 133 | 0.020 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.020 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.020 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.020 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.020 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.020 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.020 | |
| t cell activation | GO:0042110 | 289 | 0.019 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.019 | |
| regulation of binding | GO:0051098 | 111 | 0.019 | |
| regulation of defense response | GO:0031347 | 233 | 0.019 | |
| lateral inhibition | GO:0046331 | 1 | 0.019 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.019 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.019 | |
| male sex differentiation | GO:0046661 | 109 | 0.019 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.018 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.018 | |
| tissue homeostasis | GO:0001894 | 115 | 0.018 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.018 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.018 | |
| multicellular organism growth | GO:0035264 | 161 | 0.018 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.018 | |
| organelle localization | GO:0051640 | 179 | 0.018 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.018 | |
| innate immune response | GO:0045087 | 157 | 0.018 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.018 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.018 | |
| regulation of ion transport | GO:0043269 | 215 | 0.018 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.018 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.018 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.018 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.017 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.017 | |
| organelle fission | GO:0048285 | 170 | 0.017 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.017 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.017 | |
| regulation of muscle system process | GO:0090257 | 80 | 0.017 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.017 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.017 | |
| vesicle localization | GO:0051648 | 86 | 0.017 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.017 | |
| cellular modified amino acid metabolic process | GO:0006575 | 63 | 0.017 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.017 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.017 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.017 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.017 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.017 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.017 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.017 | |
| camera type eye development | GO:0043010 | 266 | 0.017 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.017 | |
| regulation of reproductive process | GO:2000241 | 66 | 0.017 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.016 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.016 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.016 | |
| t cell proliferation | GO:0042098 | 120 | 0.016 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.016 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.016 | |
| cytokine production | GO:0001816 | 319 | 0.016 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.016 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.016 | |
| heart process | GO:0003015 | 94 | 0.016 | |
| nuclear division | GO:0000280 | 158 | 0.016 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.016 | |
| localization within membrane | GO:0051668 | 4 | 0.016 | |
| protein localization to membrane | GO:0072657 | 108 | 0.016 | |
| protein import | GO:0017038 | 101 | 0.016 | |
| germ cell development | GO:0007281 | 185 | 0.016 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.016 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.015 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.015 | |
| positive regulation of growth | GO:0045927 | 104 | 0.015 | |
| male gonad development | GO:0008584 | 88 | 0.015 | |
| sensory perception | GO:0007600 | 245 | 0.015 | Mouse |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.015 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.015 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.015 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.015 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.015 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.015 | |
| placenta development | GO:0001890 | 140 | 0.015 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.015 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.015 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.015 | Mouse |
| striated muscle tissue development | GO:0014706 | 293 | 0.015 | |
| response to inorganic substance | GO:0010035 | 96 | 0.015 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.015 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.014 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.014 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.014 | |
| regulation of cell activation | GO:0050865 | 289 | 0.014 | |
| regionalization | GO:0003002 | 337 | 0.014 | |
| cell adhesion | GO:0007155 | 329 | 0.014 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.014 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.014 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.014 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.014 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.014 | |
| response to light stimulus | GO:0009416 | 135 | 0.014 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.014 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.014 | |
| regulation of response to biotic stimulus | GO:0002831 | 38 | 0.013 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.013 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.013 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.013 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.013 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.013 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.013 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.013 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.013 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.013 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.013 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.013 | |
| blood circulation | GO:0008015 | 195 | 0.013 | |
| circulatory system process | GO:0003013 | 197 | 0.013 | |
| cellularization | GO:0007349 | 1 | 0.013 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.013 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.013 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.013 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.013 | |
| response to superoxide | GO:0000303 | 16 | 0.013 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.013 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.013 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.013 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.012 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.012 | |
| removal of superoxide radicals | GO:0019430 | 12 | 0.012 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.012 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.012 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.012 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.012 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.012 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.012 | |
| negative regulation of reactive oxygen species metabolic process | GO:2000378 | 10 | 0.012 | |
| positive regulation of response to wounding | GO:1903036 | 66 | 0.012 | |
| oocyte axis specification | GO:0007309 | 2 | 0.012 | |
| b cell activation | GO:0042113 | 161 | 0.012 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.012 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.012 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.012 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.012 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.012 | |
| t cell differentiation | GO:0030217 | 174 | 0.012 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.012 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.012 | |
| retina homeostasis | GO:0001895 | 23 | 0.012 | |
| spermatid development | GO:0007286 | 108 | 0.012 | |
| chromatin modification | GO:0016568 | 187 | 0.012 | |
| forebrain development | GO:0030900 | 302 | 0.012 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.012 | |
| kidney development | GO:0001822 | 213 | 0.012 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.012 | |
| spermatid differentiation | GO:0048515 | 115 | 0.012 | |
| negative regulation of t cell differentiation | GO:0045581 | 23 | 0.012 | |
| heart contraction | GO:0060047 | 93 | 0.012 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.012 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.012 | |
| synaptic transmission | GO:0007268 | 329 | 0.012 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.012 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.012 | |
| regulation of wound healing | GO:0061041 | 40 | 0.012 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.012 | |
| protein methylation | GO:0006479 | 81 | 0.012 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.012 | |
| regulation of blood circulation | GO:1903522 | 93 | 0.012 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.012 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.011 | |
| cell fate commitment | GO:0045165 | 210 | 0.011 | |
| cognition | GO:0050890 | 149 | 0.011 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.011 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.011 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.011 | |
| fat cell differentiation | GO:0045444 | 160 | 0.011 | |
| blood coagulation | GO:0007596 | 76 | 0.011 | |
| leukocyte mediated cytotoxicity | GO:0001909 | 62 | 0.011 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.011 | |
| peptide metabolic process | GO:0006518 | 46 | 0.011 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.011 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.011 | |
| skin development | GO:0043588 | 220 | 0.011 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.011 | |
| protein ubiquitination | GO:0016567 | 171 | 0.011 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.011 | |
| regulation of synaptic plasticity | GO:0048167 | 87 | 0.011 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 40 | 0.011 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.011 | |
| developmental maturation | GO:0021700 | 193 | 0.011 | |
| maintenance of location | GO:0051235 | 89 | 0.011 | |
| interleukin 8 production | GO:0032637 | 4 | 0.010 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.010 | |
| response to acid chemical | GO:0001101 | 111 | 0.010 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.010 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.010 | |
| microtubule based process | GO:0007017 | 236 | 0.010 | |
| telencephalon development | GO:0021537 | 186 | 0.010 | |
| response to metal ion | GO:0010038 | 47 | 0.010 | |
| transcription factor import into nucleus | GO:0042991 | 26 | 0.010 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.010 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.010 | |
| maternal placenta development | GO:0001893 | 20 | 0.010 | |
| negative regulation of leukocyte differentiation | GO:1902106 | 51 | 0.010 | |
| ossification | GO:0001503 | 216 | 0.010 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.010 | |
| response to radiation | GO:0009314 | 165 | 0.010 | |
| exocytosis | GO:0006887 | 121 | 0.010 | |
| hormone metabolic process | GO:0042445 | 86 | 0.010 | |
| regulation of muscle tissue development | GO:1901861 | 97 | 0.010 | |
| l ascorbic acid metabolic process | GO:0019852 | 4 | 0.010 | |