IMP: Integrative Multi-species Prediction

Mus musculus

63 known processes

Nfyb

nuclear transcription factor-Y beta

(Aliases: Cbf-A,AA985999)

Entrez: 18045
Ensembl: ENSMUSG00000020248
UniProtKB: P63139
UniProtKB: Q8C590

Process Predictions
Disease Predictions

Nfyb biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
dna metabolic process	GO:0006259	303	0.625
cellular response to dna damage stimulus	GO:0006974	207	0.488
regulation of cellular amine metabolic process	GO:0033238	20	0.109
protein acylation	GO:0043543	64	0.108
dna repair	GO:0006281	107	0.104
protein ubiquitination	GO:0016567	171	0.098
histone modification	GO:0016570	159	0.084
cellular protein catabolic process	GO:0044257	155	0.076
organelle fission	GO:0048285	170	0.074
regulation of chromosome organization	GO:0033044	83	0.073
cellular amino acid metabolic process	GO:0006520	103	0.067
covalent chromatin modification	GO:0016569	163	0.066
cellular amine metabolic process	GO:0044106	44	0.065
chromatin organization	GO:0006325	206	0.063
rna interference	GO:0016246	2	0.058
regulation of histone modification	GO:0031056	56	0.056
rna processing	GO:0006396	105	0.054
meiotic cell cycle process	GO:1903046	77	0.054
response to growth factor	GO:0070848	198	0.053
stem cell differentiation	GO:0048863	268	0.051
negative regulation of protein metabolic process	GO:0051248	282	0.049
regulation of cellular amino acid metabolic process	GO:0006521	5	0.048
cellular macromolecule catabolic process	GO:0044265	206	0.046
cellular ketone metabolic process	GO:0042180	84	0.044
protein modification by small protein conjugation or removal	GO:0070647	207	0.044
histone acetylation	GO:0016573	41	0.042
amine metabolic process	GO:0009308	45	0.041
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	56	0.041
mrna processing	GO:0006397	63	0.040
mitotic cell cycle process	GO:1903047	159	0.039
peptidyl amino acid modification	GO:0018193	336	0.039
mrna metabolic process	GO:0016071	84	0.038
regulation of cellular ketone metabolic process	GO:0010565	66	0.037
rna splicing via transesterification reactions	GO:0000375	43	0.037
chromatin modification	GO:0016568	187	0.036
negative regulation of protein modification process	GO:0031400	163	0.034
microtubule based process	GO:0007017	236	0.034
stem cell development	GO:0048864	219	0.034
meiotic cell cycle	GO:0051321	122	0.034
nuclear division	GO:0000280	158	0.033
regulation of chromatin modification	GO:1903308	57	0.032
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.030
nucleic acid phosphodiester bond hydrolysis	GO:0090305	49	0.029
modification dependent protein catabolic process	GO:0019941	133	0.029
negative regulation of molecular function	GO:0044092	258	0.029
response to radiation	GO:0009314	165	0.028
regulation of cellular component biogenesis	GO:0044087	181	0.028
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.028
stem cell maintenance	GO:0019827	130	0.027
regulation of organelle organization	GO:0033043	289	0.026
regulation of cell cycle	GO:0051726	281	0.026
regulation of kinase activity	GO:0043549	249	0.025
methylation	GO:0032259	134	0.025
response to oxidative stress	GO:0006979	123	0.024
mitotic cell cycle	GO:0000278	195	0.024
negative regulation of cellular protein metabolic process	GO:0032269	247	0.024
protein modification by small protein conjugation	GO:0032446	187	0.023
regulation of protein catabolic process	GO:0042176	108	0.023
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.023
macromolecule catabolic process	GO:0009057	281	0.023
rna 3 end processing	GO:0031123	20	0.022
organelle localization	GO:0051640	179	0.022
regulation of cell cycle process	GO:0010564	160	0.022
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.022
mitotic sister chromatid cohesion	GO:0007064	1	0.021
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.021
negative regulation of cellular component organization	GO:0051129	194	0.020
protein methylation	GO:0006479	81	0.020
protein alkylation	GO:0008213	81	0.019
peptidyl lysine modification	GO:0018205	77	0.019
cell division	GO:0051301	120	0.019
gene silencing	GO:0016458	38	0.019
spermatid differentiation	GO:0048515	115	0.019
histone mrna metabolic process	GO:0008334	3	0.018
regulation of transferase activity	GO:0051338	263	0.018
respiratory system development	GO:0060541	190	0.018
macromolecule methylation	GO:0043414	120	0.018
mapk cascade	GO:0000165	281	0.018	Fly
nucleobase containing small molecule metabolic process	GO:0055086	352	0.018
mrna splicing via spliceosome	GO:0000398	43	0.017
protein catabolic process	GO:0030163	221	0.017
response to peptide	GO:1901652	136	0.017
response to light stimulus	GO:0009416	135	0.016
regulation of cellular response to stress	GO:0080135	159	0.016
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.016
leukocyte differentiation	GO:0002521	342	0.016
aromatic compound catabolic process	GO:0019439	286	0.016
maintenance of protein location in nucleus	GO:0051457	2	0.016
cellular component assembly involved in morphogenesis	GO:0010927	139	0.015
myeloid cell differentiation	GO:0030099	233	0.015
nucleus organization	GO:0006997	45	0.015
double strand break repair	GO:0006302	48	0.015
regulation of chromatin organization	GO:1902275	57	0.015
establishment of organelle localization	GO:0051656	122	0.015
ubiquitin dependent protein catabolic process	GO:0006511	129	0.014
b cell activation	GO:0042113	161	0.014
muscle cell differentiation	GO:0042692	261	0.014
respiratory tube development	GO:0030323	167	0.014
microtubule cytoskeleton organization	GO:0000226	157	0.014
nitrogen compound transport	GO:0071705	271	0.014
peptidyl lysine acetylation	GO:0018394	45	0.014
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.014
regulation of protein kinase activity	GO:0045859	232	0.014
proteasomal protein catabolic process	GO:0010498	98	0.014
oocyte axis specification	GO:0007309	2	0.014
spermatid development	GO:0007286	108	0.014
dna dependent dna replication	GO:0006261	24	0.014
posttranscriptional gene silencing	GO:0016441	10	0.013
regulation of peptidyl lysine acetylation	GO:2000756	22	0.013
meiotic nuclear division	GO:0007126	115	0.012
positive regulation of nervous system development	GO:0051962	221	0.012	Fly
asymmetric stem cell division	GO:0098722	3	0.012
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	2	0.012
regulation of mapk cascade	GO:0043408	248	0.012	Fly
termination of rna polymerase ii transcription	GO:0006369	1	0.012
regulation of response to dna damage stimulus	GO:2001020	34	0.012
nucleocytoplasmic transport	GO:0006913	139	0.012
homeostasis of number of cells	GO:0048872	210	0.012
cell maturation	GO:0048469	127	0.012
internal peptidyl lysine acetylation	GO:0018393	42	0.012
mesenchymal cell differentiation	GO:0048762	107	0.012
maintenance of location	GO:0051235	89	0.012
regulation of circadian rhythm	GO:0042752	58	0.012
nucleotide metabolic process	GO:0009117	332	0.011
chromosome segregation	GO:0007059	48	0.011
palate development	GO:0060021	76	0.011
response to organonitrogen compound	GO:0010243	246	0.011
dephosphorylation	GO:0016311	129	0.011
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	40	0.011
myeloid cell homeostasis	GO:0002262	114	0.011
erbb signaling pathway	GO:0038127	32	0.011
intracellular mrna localization	GO:0008298	4	0.011
internal protein amino acid acetylation	GO:0006475	42	0.011
protein lipidation	GO:0006497	28	0.011
protein dna complex subunit organization	GO:0071824	28	0.011
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.010
regulation of histone acetylation	GO:0035065	19	0.010
male gamete generation	GO:0048232	285	0.010
positive regulation of protein complex assembly	GO:0031334	45	0.010

Nfyb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.018
central nervous system disease	DOID:331	0.018
disease of anatomical entity	DOID:7	0.018

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