Mus musculus

95 known processes

Pde6h

phosphodiesterase 6H, cGMP-specific, cone, gamma

(Aliases: PDEgamma,A930033D18Rik)

Pde6h biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
phototransductionGO:0007602170.281
rhodopsin mediated signaling pathwayGO:001605640.257
response to light stimulusGO:00094161350.205
response to radiationGO:00093141650.177
detection of light stimulusGO:0009583250.174
visual perceptionGO:0007601520.154
transmembrane transportGO:00550854120.152
purine nucleotide metabolic processGO:00061633020.133
ion transmembrane transportGO:00342203610.120
purine ribonucleotide metabolic processGO:00091502900.108
nucleoside phosphate metabolic processGO:00067533380.096
regulation of nucleotide metabolic processGO:00061401690.096
nitrogen compound transportGO:00717052710.090
amine metabolic processGO:0009308450.089
nucleotide metabolic processGO:00091173320.087
eye photoreceptor cell developmentGO:0042462310.084
detection of stimulusGO:0051606840.083
detection of external stimulusGO:0009581610.082
ribonucleotide metabolic processGO:00092592910.080
regulation of membrane potentialGO:00423911920.077
camera type eye developmentGO:00430102660.075
g protein coupled receptor signaling pathwayGO:00071862430.074
sensory perceptionGO:00076002450.073
nucleobase containing small molecule metabolic processGO:00550863520.071
ribose phosphate metabolic processGO:00196932910.071
detection of abiotic stimulusGO:0009582600.068
cellular homeostasisGO:00197252400.068
ribonucleotide biosynthetic processGO:0009260590.067
regulation of secretion by cellGO:19035302490.067
carbohydrate derivative biosynthetic processGO:19011371830.067
purine containing compound metabolic processGO:00725213110.066
regulation of purine nucleotide metabolic processGO:19005421690.066
ribose phosphate biosynthetic processGO:0046390590.065
cellular chemical homeostasisGO:00550822150.065
retinal cone cell developmentGO:004654980.065
cellular divalent inorganic cation homeostasisGO:00725031270.064
photoreceptor cell developmentGO:0042461400.064
sensory perception of light stimulusGO:0050953540.063
eye photoreceptor cell differentiationGO:0001754410.063
regulation of protein kinase activityGO:00458592320.061
cellular amine metabolic processGO:0044106440.060
organophosphate biosynthetic processGO:00904071220.059
heart contractionGO:0060047930.059
organic hydroxy compound metabolic processGO:19016152030.058
detection of visible lightGO:0009584140.056
purine nucleotide biosynthetic processGO:0006164650.055
peptide hormone secretionGO:00300721090.054
retina development in camera type eyeGO:00600411190.053
muscle contractionGO:00069361010.052
activation of transmembrane receptor protein tyrosine kinase activityGO:000717130.050
phototransduction visible lightGO:000760360.049
forebrain developmentGO:00309003020.049
organic cyclic compound catabolic processGO:19013612950.049
purine containing compound biosynthetic processGO:0072522700.049
organic anion transportGO:00157111370.048
purine ribonucleotide biosynthetic processGO:0009152590.048
cyclic nucleotide metabolic processGO:0009187590.048
nucleotide biosynthetic processGO:0009165780.047
cellular metal ion homeostasisGO:00068751510.047
response to organonitrogen compoundGO:00102432460.047
oxidation reduction processGO:00551143420.046
inorganic cation transmembrane transportGO:00986622070.045
organic hydroxy compound transportGO:0015850930.045
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.045
cellular amino acid metabolic processGO:00065201030.044
anatomical structure homeostasisGO:00602491450.044
cellular calcium ion homeostasisGO:00068741190.043
t cell activationGO:00421102890.043
ras protein signal transductionGO:0007265770.042
photoreceptor cell differentiationGO:0046530520.042
organonitrogen compound biosynthetic processGO:19015661920.042
peptide transportGO:00158331330.040
leukocyte differentiationGO:00025213420.040
divalent metal ion transportGO:00708381720.039
calcium ion transportGO:00068161590.039
regulation of feeding behaviorGO:006025930.039
regulation of nucleotide biosynthetic processGO:0030808340.039
heart processGO:0003015940.039
membrane depolarizationGO:0051899640.039
regulation of dopamine secretionGO:001405990.038
negative regulation of phosphorus metabolic processGO:00105631840.038
regulation of kinase activityGO:00435492490.038
amide transportGO:00428861380.037
regulation of camp metabolic processGO:0030814300.037
norepinephrine transportGO:001587420.037
circulatory system processGO:00030131970.037
cation transportGO:00068123990.037
synaptic transmissionGO:00072683290.037
multicellular organismal homeostasisGO:00488711640.036
regulation of hydrolase activityGO:00513362460.036
positive regulation of secretionGO:00510471300.035
regulation of cytokine productionGO:00018172660.035
nucleotide catabolic processGO:00091662170.035
cytokine productionGO:00018163190.035
positive regulation of transferase activityGO:00513471670.035
regulation of ion transportGO:00432692150.035
norepinephrine secretionGO:004824320.034
positive regulation of nucleotide metabolic processGO:00459811140.034
regulation of system processGO:00440572000.033
glycosyl compound metabolic processGO:19016572460.033
response to nutrient levelsGO:00316671090.033
metal ion homeostasisGO:00550651890.033
regulation of neuron differentiationGO:00456642810.033
positive regulation of catecholamine secretionGO:003360520.032
retinal cone cell differentiationGO:004267080.032
ribonucleoside metabolic processGO:00091192450.032
camp biosynthetic processGO:0006171310.032
photoreceptor cell maintenanceGO:0045494190.032
sensory organ morphogenesisGO:00905962420.031
regulation of cellular amino acid metabolic processGO:000652150.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
neuron neuron synaptic transmissionGO:0007270690.031
cyclic nucleotide biosynthetic processGO:0009190440.031
regulation of circadian sleep wake cycle sleepGO:004518730.031
blood circulationGO:00080151950.031
regulation of cell activationGO:00508652890.030
regulation of heart contractionGO:0008016770.030
tissue homeostasisGO:00018941150.030
carbohydrate derivative catabolic processGO:19011362310.030
positive regulation of dopamine secretionGO:003360320.030
regulation of protein serine threonine kinase activityGO:00719001570.029
regulation of cellular amine metabolic processGO:0033238200.029
myeloid leukocyte differentiationGO:00025731190.029
positive regulation of secretion by cellGO:19035321140.029
carboxylic acid transportGO:00469421000.029
regulation of cellular ketone metabolic processGO:0010565660.029
camp metabolic processGO:0046058400.029
muscle system processGO:00030121410.029
negative regulation of phosphate metabolic processGO:00459361840.028
cellular nitrogen compound catabolic processGO:00442702800.028
regulation of acetylcholine secretion neurotransmissionGO:001405620.028
regulation of cyclic nucleotide metabolic processGO:0030799400.028
cellular response to radiationGO:0071478280.028
negative regulation of cell proliferationGO:00082852960.027
regulation of norepinephrine secretionGO:001406120.027
regulation of map kinase activityGO:00434051200.027
divalent inorganic cation homeostasisGO:00725071380.027
cellular ion homeostasisGO:00068731650.026
glycosyl compound catabolic processGO:19016582060.026
cellular response to organonitrogen compoundGO:00714171450.026
conditioned taste aversionGO:000166140.026
regulation of defense responseGO:00313472330.026
epithelial cell developmentGO:00020641590.026
regulation of inflammatory responseGO:00507271470.026
regulation of secretionGO:00510462740.026
second messenger mediated signalingGO:0019932730.025
neurotransmitter transportGO:0006836760.025
cellular response to abiotic stimulusGO:0071214560.025
cellular ketone metabolic processGO:0042180840.025
purine ribonucleoside metabolic processGO:00461282410.025
cyclic purine nucleotide metabolic processGO:0052652430.025
protein localization to organelleGO:00333651850.025
regulation of protein localizationGO:00328802310.025
cation homeostasisGO:00550802120.024
positive regulation of hormone secretionGO:0046887380.024
aromatic compound catabolic processGO:00194392860.024
positive regulation of purine nucleotide metabolic processGO:19005441140.024
sensory perception of chemical stimulusGO:0007606510.024
nucleoside phosphate biosynthetic processGO:1901293790.024
inflammatory responseGO:00069542440.023
retina homeostasisGO:0001895230.023
neural retina developmentGO:0003407410.023
cellular lipid metabolic processGO:00442553230.023
sodium ion transmembrane transportGO:0035725490.023
regulation of homeostatic processGO:00328441820.023
regulation of transferase activityGO:00513382630.023
nucleoside metabolic processGO:00091162460.023
regulation of excitatory postsynaptic membrane potentialGO:0060079410.023
adult locomotory behaviorGO:0008344910.023
catecholamine secretionGO:0050432150.023
mapk cascadeGO:00001652810.023
regulation of lymphocyte activationGO:00512492400.023
positive regulation of protein modification processGO:00314012990.023
purine nucleoside metabolic processGO:00422782410.022
cellular response to light stimulusGO:0071482190.022
regulation of neurotransmitter levelsGO:0001505870.022
lymphocyte proliferationGO:00466511640.022
regulation of postsynaptic membrane potentialGO:0060078480.022
regulation of cyclic nucleotide biosynthetic processGO:0030802310.022
cation transmembrane transportGO:00986552660.022
synaptic transmission glutamatergicGO:0035249360.022
smooth muscle contractionGO:0006939440.021
photoreceptor cell morphogenesisGO:000859430.021
regulation of blood pressureGO:0008217930.021
regulation of ion transmembrane transportGO:00347651190.021
ribonucleotide catabolic processGO:00092612080.021
purine nucleotide catabolic processGO:00061952110.020
cellular response to lipidGO:00713961450.020
regulation of muscle contractionGO:0006937490.020
response to organic cyclic compoundGO:00140701980.020
peptide secretionGO:00027901140.020
anion transportGO:00068201770.020
spermatogenesisGO:00072832840.020
nucleoside triphosphate metabolic processGO:00091412300.020
nucleoside triphosphate catabolic processGO:00091432050.019
cellular response to acid chemicalGO:0071229680.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
organelle localizationGO:00516401790.019
rho protein signal transductionGO:0007266320.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
organophosphate catabolic processGO:00464342320.019
regulation of camp biosynthetic processGO:0030817250.019
negative regulation of immune system processGO:00026832090.019
regulation of peptide transportGO:0090087910.019
regulation of cyclase activityGO:0031279130.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
regulation of transmembrane transportGO:00347621280.019
establishment of organelle localizationGO:00516561220.019
action potentialGO:0001508780.019
organic acid transportGO:00158491010.019
adult behaviorGO:00305341350.019
carbohydrate metabolic processGO:00059752300.019
rhythmic processGO:00485111740.019
regulation of action potentialGO:009890040.018
microtubule based processGO:00070172360.018
generation of precursor metabolites and energyGO:00060911030.018
heterocycle catabolic processGO:00467002800.018
muscle cell developmentGO:00550011330.018
synaptic transmission involved in micturitionGO:006008430.018
ribonucleoside catabolic processGO:00424542060.018
sequestering of calcium ionGO:0051208180.018
regulation of establishment of protein localizationGO:00702011810.018
regulation of hormone levelsGO:00108172110.018
negative regulation of molecular functionGO:00440922580.018
sensory perception of smellGO:0007608260.018
negative regulation of transferase activityGO:0051348850.018
regulation of cellular component biogenesisGO:00440871810.018
regulation of response to woundingGO:19030341890.017
visual behaviorGO:0007632450.017
ribonucleoside triphosphate catabolic processGO:00092031990.017
cgmp metabolic processGO:0046068200.017
regulation of gtp catabolic processGO:00331241130.017
regulation of protein transportGO:00512231630.017
generation of ovulation cycle rhythmGO:006011210.017
monoamine transportGO:0015844330.017
male gamete generationGO:00482322850.017
regulation of circadian sleep wake cycleGO:004274930.017
purine ribonucleotide catabolic processGO:00091542080.017
positive regulation of homeostatic processGO:0032846640.017
positive regulation of cell developmentGO:00107202370.017
regulation of catecholamine secretionGO:0050433120.017
regulation of blood circulationGO:1903522930.017
positive regulation of defense responseGO:00313491240.017
regulation of hormone secretionGO:0046883880.017
macromolecule methylationGO:00434141200.017
small gtpase mediated signal transductionGO:0007264970.017
negative regulation of cyclase activityGO:003128010.017
embryonic organ morphogenesisGO:00485622760.017
positive regulation of protein kinase activityGO:00458601440.017
ribonucleoside triphosphate metabolic processGO:00091992200.016
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200260.016
acetylcholine secretion neurotransmissionGO:001405520.016
cytoplasmic transportGO:00164822340.016
circadian rhythmGO:00076231140.016
purine ribonucleoside triphosphate catabolic processGO:00092071990.016
monosaccharide metabolic processGO:00059961060.016
regulation of cell projection organizationGO:00313442060.016
negative regulation of phosphorylationGO:00423261660.016
neurotransmitter secretionGO:0007269620.016
multicellular organism growthGO:00352641610.016
regulation of neurotransmitter transportGO:0051588350.016
dna metabolic processGO:00062593030.016
negative regulation of purine nucleotide metabolic processGO:1900543160.016
apoptotic signaling pathwayGO:00971903060.016
cell type specific apoptotic processGO:00972852680.016
calcium ion homeostasisGO:00550741270.016
gtp catabolic processGO:00061841430.016
methylationGO:00322591340.016
muscle tissue developmentGO:00605373080.016
hormone secretionGO:00468791280.016
maintenance of locationGO:0051235890.016
exploration behaviorGO:0035640210.016
intracellular protein transportGO:00068862040.016
positive regulation of peptide secretionGO:0002793330.015
regulation of muscle system processGO:0090257800.015
leukocyte proliferationGO:00706611720.015
protein kinase b signalingGO:0043491740.015
positive regulation of peptide hormone secretionGO:0090277310.015
adaptation of rhodopsin mediated signalingGO:001606220.015
exocytosisGO:00068871210.015
nucleoside phosphate catabolic processGO:19012922220.015
regulation of cellular catabolic processGO:00313292420.015
response to extracellular stimulusGO:00099911270.015
negative regulation of action potentialGO:004575910.015
posttranscriptional regulation of gene expressionGO:00106081550.015
blood vessel morphogenesisGO:00485142850.015
dopamine secretionGO:001404690.015
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressureGO:000198810.015
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.015
dephosphorylationGO:00163111290.015
cell activation involved in immune responseGO:00022631260.015
positive regulation of cytosolic calcium ion concentrationGO:0007204650.015
regulation of amine transportGO:0051952210.015
monocarboxylic acid metabolic processGO:00327871910.015
regulation of t cell activationGO:00508631700.014
response to acid chemicalGO:00011011110.014
inorganic ion transmembrane transportGO:00986602340.014
myeloid cell differentiationGO:00300992330.014
purine nucleoside catabolic processGO:00061522050.014
regulation of body fluid levelsGO:00508781620.014
regulation of protein kinase b signalingGO:0051896560.014
neuron apoptotic processGO:00514021420.014
regulation of neurotransmitter secretionGO:0046928290.014
regulation of peptide hormone secretionGO:0090276750.014
acetylcholine transportGO:001587020.014
alpha beta t cell activationGO:0046631910.014
positive regulation of cellular catabolic processGO:00313311480.014
catecholamine transportGO:0051937210.014
endocytosisGO:00068971680.014
regulation of nucleoside metabolic processGO:00091181300.014
peptidyl amino acid modificationGO:00181933360.014
cytosolic calcium ion homeostasisGO:0051480700.014
osteoclast differentiationGO:0030316620.014
body fluid secretionGO:0007589530.014
positive regulation of protein phosphorylationGO:00019342420.014
nucleoside catabolic processGO:00091642060.014
divalent inorganic cation transportGO:00725111780.014
purine ribonucleoside catabolic processGO:00461302050.013
response to drugGO:0042493750.013
positive regulation of hydrolase activityGO:00513451480.013
cardiac muscle contractionGO:0060048320.013
camera type eye photoreceptor cell differentiationGO:0060219150.013
activation of adenylate cyclase activityGO:000719040.013
negative regulation of cell developmentGO:00107211690.013
striated muscle contractionGO:0006941450.013
regulation of circadian rhythmGO:0042752580.013
positive regulation of cellular amine metabolic processGO:003324050.013
cellular response to external stimulusGO:0071496880.013
lens development in camera type eyeGO:0002088620.013
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.013
neuron deathGO:00709971540.013
memoryGO:0007613580.013
regulation of renin secretion into blood streamGO:190013340.013
positive regulation of camp mediated signalingGO:004395030.013
gland developmentGO:00487323300.013
response to oxygen levelsGO:0070482620.013
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.013
transepithelial chloride transportGO:003032140.013
positive regulation of synaptic transmission dopaminergicGO:003222650.013
sperm motilityGO:0030317470.013
positive regulation of cytokine productionGO:00018191740.013
erk1 and erk2 cascadeGO:0070371770.013
tumor necrosis factor superfamily cytokine productionGO:0071706510.013
insulin secretionGO:0030073890.013
actin filament based movementGO:0030048230.012
negative regulation of protein phosphorylationGO:00019331260.012
glucose metabolic processGO:0006006920.012
positive regulation of ion transportGO:0043270650.012
spermatid developmentGO:00072861080.012
sodium ion transportGO:0006814730.012
dopamine metabolic processGO:0042417230.012
cell adhesionGO:00071553290.012
negative regulation of kinase activityGO:0033673810.012
fat cell differentiationGO:00454441600.012
calcium ion transmembrane transportGO:0070588850.012
negative regulation of defense responseGO:0031348770.012
striated muscle tissue developmentGO:00147062930.012
gastrulationGO:00073691160.012
ear morphogenesisGO:00424711180.012
multicellular organismal signalingGO:0035637910.012
acetate ester transportGO:190137420.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
carboxylic acid biosynthetic processGO:0046394860.012
regulation of purine nucleotide catabolic processGO:00331211220.012
regulation of lipid metabolic processGO:00192161180.012
learningGO:0007612980.012
central nervous system neuron differentiationGO:00219531620.012
cellular carbohydrate metabolic processGO:00442621190.012
cognitionGO:00508901490.012
dendrite developmentGO:00163581150.012
cellular protein complex assemblyGO:00436231160.012
glucose homeostasisGO:00425931280.012
purine containing compound catabolic processGO:00725232130.012
skin developmentGO:00435882200.012
dopamine transportGO:0015872150.012
carbohydrate homeostasisGO:00335001280.012
membrane hyperpolarizationGO:0060081210.012
anion transmembrane transportGO:0098656710.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
visual learningGO:0008542440.011
learning or memoryGO:00076111480.011
regulation of mapk cascadeGO:00434082480.011
regulation of anatomical structure sizeGO:00900661780.011
negative regulation of intracellular signal transductionGO:19025321670.011
amino acid transportGO:0006865610.011
regulation of protein secretionGO:0050708820.011
circadian sleep wake cycle non rem sleepGO:004274820.011
negative regulation of cellular component organizationGO:00511291940.011
multi multicellular organism processGO:00447061090.011
energy derivation by oxidation of organic compoundsGO:0015980770.011
wound healingGO:00420601570.011
immune response activating signal transductionGO:00027571160.011
b cell activationGO:00421131610.011
negative regulation of toll signaling pathwayGO:004575110.011
reactive oxygen species metabolic processGO:0072593840.011
negative regulation of inflammatory responseGO:0050728610.011
organonitrogen compound catabolic processGO:19015652640.011
angiogenesisGO:00015252010.011
immune response regulating signaling pathwayGO:00027641250.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
monocarboxylic acid transportGO:0015718440.011
ventricular cardiac muscle cell action potentialGO:008600540.011
organic acid biosynthetic processGO:0016053860.011
lymphocyte differentiationGO:00300982420.011
regulation of proteolysisGO:00301621640.011
gtp metabolic processGO:00460391440.011
lipid localizationGO:00108761260.011
regulation of lymphocyte differentiationGO:00456191070.011
regulation of leukocyte differentiationGO:19021051590.011
regulation of satellite cell activation involved in skeletal muscle regenerationGO:001471730.011
regulation of lymphocyte proliferationGO:00506701170.010
response to monosaccharideGO:0034284670.010
cytokine mediated signaling pathwayGO:00192211150.010
neural precursor cell proliferationGO:00613511210.010
positive regulation of mapk cascadeGO:00434101700.010
monosaccharide transportGO:0015749580.010
circadian sleep wake cycle rem sleepGO:004274710.010
telencephalon developmentGO:00215371860.010
regulation of circadian sleep wake cycle non rem sleepGO:004518810.010
multicellular organismal response to stressGO:0033555620.010
lymphocyte activation involved in immune responseGO:0002285930.010
protein modification by small protein removalGO:0070646210.010
ossificationGO:00015032160.010
septum primum developmentGO:000328440.010
regulation of ossificationGO:00302781120.010
regulation of organ morphogenesisGO:20000271440.010
pigmentationGO:0043473710.010
protein localization to nucleusGO:00345041210.010
myosin filament assemblyGO:003103420.010
cellular component assembly involved in morphogenesisGO:00109271390.010
positive regulation of gtpase activityGO:0043547850.010
associative learningGO:0008306610.010
regulation of myeloid leukocyte differentiationGO:0002761580.010
regulation of blood vessel sizeGO:0050880560.010

Pde6h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye and adnexa diseaseDOID:149200.356
eye diseaseDOID:561400.356
sensory system diseaseDOID:005015500.356
disease of anatomical entityDOID:700.356
nervous system diseaseDOID:86300.356
retinal diseaseDOID:567900.208
retinal degenerationDOID:846600.051
retinitis pigmentosaDOID:1058400.037
disease of cellular proliferationDOID:1456600.011