Mus musculus

63 known processes

Thoc2

THO complex 2

(Aliases: Gm1139,D130005M13Rik,Gm1793,6330441O12Rik,Tho2)

Thoc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063252060.361
histone h3 k9 trimethylationGO:003612460.274
heterochromatin organizationGO:007082840.232
histone methylationGO:0016571710.191
organonitrogen compound catabolic processGO:19015652640.162
rna interferenceGO:001624620.162
rna splicingGO:0008380540.158
dna replication independent nucleosome assemblyGO:000633610.152
purine nucleoside triphosphate metabolic processGO:00091442260.150
positive regulation of chromosome organizationGO:2001252330.144
organic cyclic compound catabolic processGO:19013612950.138
heterocycle catabolic processGO:00467002800.136
glycosyl compound catabolic processGO:19016582060.136
chromatin modificationGO:00165681870.136
purine ribonucleotide catabolic processGO:00091542080.133
purine nucleoside catabolic processGO:00061522050.122
ribose phosphate metabolic processGO:00196932910.116
nucleotide metabolic processGO:00091173320.112
cellular nitrogen compound catabolic processGO:00442702800.106
nucleobase containing small molecule metabolic processGO:00550863520.105
organophosphate catabolic processGO:00464342320.101
purine ribonucleoside catabolic processGO:00461302050.099
methylationGO:00322591340.099
purine ribonucleoside triphosphate catabolic processGO:00092071990.098
purine nucleoside triphosphate catabolic processGO:00091462030.098
regulation of mrna processingGO:0050684410.098
positive regulation of organelle organizationGO:00106381280.097
alternative mrna splicing via spliceosomeGO:0000380120.097
purine ribonucleotide metabolic processGO:00091502900.097
epithelial cell developmentGO:00020641590.097
regulation of rna splicingGO:0043484370.095
regulation of transcription by chromatin organizationGO:003440100.090
purine nucleotide metabolic processGO:00061633020.089
nucleoside triphosphate catabolic processGO:00091432050.088
ribonucleoside catabolic processGO:00424542060.085
histone h3 k9 methylationGO:0051567170.085
purine containing compound metabolic processGO:00725213110.085
purine containing compound catabolic processGO:00725232130.083
nucleotide catabolic processGO:00091662170.083
sensory perception of mechanical stimulusGO:00509541070.080
glycosyl compound metabolic processGO:19016572460.075
nucleoside metabolic processGO:00091162460.075
purine ribonucleoside metabolic processGO:00461282410.074
meiotic cell cycleGO:00513211220.074
positive regulation of mapk cascadeGO:00434101700.073
gene silencingGO:0016458380.073
positive regulation of cellular amine metabolic processGO:003324050.073
regulation of cell cycle processGO:00105641600.071
ribonucleotide catabolic processGO:00092612080.071
histone lysine methylationGO:0034968500.070
posttranscriptional regulation of gene expressionGO:00106081550.069
osteoclast fusionGO:007267530.069
endocytosisGO:00068971680.068
cellular response to dna damage stimulusGO:00069742070.068
dna conformation changeGO:0071103370.068
purine ribonucleoside monophosphate metabolic processGO:0009167800.067
synaptic transmissionGO:00072683290.067
nucleoside phosphate metabolic processGO:00067533380.067
aromatic compound catabolic processGO:00194392860.066
nucleoside phosphate catabolic processGO:19012922220.066
intracellular mrna localizationGO:000829840.064
chromosome organization involved in meiosisGO:0070192390.063
regulation of alternative mrna splicing via spliceosomeGO:000038180.062
carbohydrate derivative catabolic processGO:19011362310.062
nucleoside triphosphate metabolic processGO:00091412300.062
mrna metabolic processGO:0016071840.059
gene silencing by rnaGO:0031047190.059
chromatin assemblyGO:0031497130.058
regulation of organelle organizationGO:00330432890.058
ribonucleoside monophosphate metabolic processGO:0009161800.057
ribonucleoside monophosphate catabolic processGO:0009158570.056
mapk cascadeGO:00001652810.055
sensory perceptionGO:00076002450.054
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.054
purine nucleoside metabolic processGO:00422782410.054
histone modificationGO:00165701590.053
development of primary sexual characteristicsGO:00451371430.052
regulation of cellular ketone metabolic processGO:0010565660.052
regulation of system processGO:00440572000.051
dna packagingGO:0006323300.051
ribonucleotide metabolic processGO:00092592910.050
chromatin assembly or disassemblyGO:0006333160.050
atp catabolic processGO:0006200550.050
regulation of meiotic cell cycleGO:0051445340.050
posttranscriptional gene silencingGO:0016441100.049
positive regulation of chromatin modificationGO:1903310280.049
regulation of cell cycleGO:00517262810.048
positive regulation of histone modificationGO:0031058280.047
ras protein signal transductionGO:0007265770.047
regulation of mapk cascadeGO:00434082480.046
nucleoside monophosphate catabolic processGO:0009125590.046
macromolecule methylationGO:00434141200.046
purine ribonucleoside triphosphate metabolic processGO:00092052200.045
cell type specific apoptotic processGO:00972852680.044
nucleoside catabolic processGO:00091642060.043
positive regulation of necrotic cell deathGO:001094010.042
mitotic sister chromatid cohesionGO:000706410.040
uterus morphogenesisGO:006103820.039
apoptotic signaling pathwayGO:00971903060.038
spermatogenesisGO:00072832840.038
mitotic cell cycleGO:00002781950.037
gonad developmentGO:00084061410.037
purine nucleotide catabolic processGO:00061952110.037
posttranscriptional gene silencing by rnaGO:0035194100.036
atp metabolic processGO:0046034750.036
oogenesisGO:0048477560.036
dna metabolic processGO:00062593030.035
regulation of chromosome organizationGO:0033044830.035
cellular amino acid metabolic processGO:00065201030.035
ribonucleoside triphosphate metabolic processGO:00091992200.035
positive regulation of cell cycle processGO:0090068610.035
positive regulation of protein modification processGO:00314012990.035
positive regulation of cell cycleGO:0045787920.034
protein methylationGO:0006479810.034
neural tube developmentGO:00219151600.033
chromatin silencingGO:0006342150.033
lateral inhibitionGO:004633110.033
mrna processingGO:0006397630.032
regulation of mrna splicing via spliceosomeGO:0048024320.032
meiotic nuclear divisionGO:00071261150.032
cellular response to lipidGO:00713961450.032
multinuclear osteoclast differentiationGO:007267440.032
sensory perception of soundGO:0007605970.031
negative regulation of intracellular signal transductionGO:19025321670.031
nucleoside monophosphate metabolic processGO:0009123850.030
heterochromatin organization involved in chromatin silencingGO:007086810.029
regulation of hydrolase activityGO:00513362460.029
protein deacetylationGO:0006476320.028
regulation of cell divisionGO:0051302760.028
purine ribonucleoside monophosphate catabolic processGO:0009169570.028
protein localization to organelleGO:00333651850.028
ribonucleoside triphosphate catabolic processGO:00092031990.027
positive regulation of histone h3 k9 methylationGO:005157440.027
purine nucleoside monophosphate metabolic processGO:0009126810.026
protein dna complex subunit organizationGO:0071824280.026
histone h4 k20 methylationGO:003477080.026
cellular ketone metabolic processGO:0042180840.025
rna processingGO:00063961050.025
learning or memoryGO:00076111480.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
gtp catabolic processGO:00061841430.025
mitochondrion organizationGO:00070051340.025
purine nucleoside monophosphate catabolic processGO:0009128580.024
rna splicing via transesterification reactionsGO:0000375430.024
negative regulation of molecular functionGO:00440922580.024
regulation of protein localizationGO:00328802310.024
sertoli cell developmentGO:0060009150.024
muscle contractionGO:00069361010.024
cation homeostasisGO:00550802120.023
synapse organizationGO:00508081250.023
chromatin remodelingGO:0006338320.023
negative regulation of phosphorylationGO:00423261660.023
small gtpase mediated signal transductionGO:0007264970.023
macromolecule deacylationGO:0098732370.023
mitotic nuclear divisionGO:0007067480.023
regulation of cellular amine metabolic processGO:0033238200.022
compound eye developmentGO:004874910.022
extrinsic apoptotic signaling pathwayGO:00971911260.021
ribonucleoside metabolic processGO:00091192450.021
mrna splicing via spliceosomeGO:0000398430.021
regulation of cellular response to stressGO:00801351590.021
covalent chromatin modificationGO:00165691630.021
response to extracellular stimulusGO:00099911270.020
regulation of mrna stabilityGO:0043488230.020
membrane organizationGO:00610242450.020
cellular homeostasisGO:00197252400.020
nuclear divisionGO:00002801580.020
meiotic cell cycle processGO:1903046770.020
cell cycle checkpointGO:0000075470.019
meiosis iGO:0007127600.019
forebrain developmentGO:00309003020.019
regulation of mrna metabolic processGO:1903311430.019
chromatin silencing at rdnaGO:000018330.019
receptor mediated endocytosisGO:0006898510.019
protein deacylationGO:0035601360.019
interkinetic nuclear migrationGO:002202780.019
innate immune responseGO:00450871570.019
dna dependent dna replication maintenance of fidelityGO:004500530.018
oocyte axis specificationGO:000730920.018
positive regulation of homeostatic processGO:0032846640.018
positive regulation of apoptotic processGO:00430652170.018
negative regulation of nervous system developmentGO:00519611560.018
establishment of vesicle localizationGO:0051650810.018
microtubule cytoskeleton organizationGO:00002261570.018
microtubule based processGO:00070172360.018
cellular ion homeostasisGO:00068731650.018
neural precursor cell proliferationGO:00613511210.017
germ cell developmentGO:00072811850.017
regulation of protein maturationGO:1903317960.017
cognitionGO:00508901490.017
ribonucleoprotein complex subunit organizationGO:0071826280.017
dna methylation involved in gamete generationGO:0043046150.017
negative regulation of phosphate metabolic processGO:00459361840.017
axonogenesisGO:00074092740.016
negative regulation of protein metabolic processGO:00512482820.016
androgen biosynthetic processGO:000670240.016
regulation of ras protein signal transductionGO:00465781140.016
positive regulation of potassium ion transportGO:004326830.016
dendrite developmentGO:00163581150.016
calcium ion transportGO:00068161590.016
trna wobble uridine modificationGO:000209820.016
female gamete generationGO:0007292740.016
oxidation reduction processGO:00551143420.015
leukocyte migrationGO:00509001240.015
stem cell differentiationGO:00488632680.015
organelle localizationGO:00516401790.015
cellular metal ion homeostasisGO:00068751510.015
establishment or maintenance of polarity of embryonic epitheliumGO:001633210.015
rhythmic processGO:00485111740.015
regulation of nuclear divisionGO:0051783560.015
organic hydroxy compound metabolic processGO:19016152030.014
regulation of cell motilityGO:20001452360.014
divalent inorganic cation homeostasisGO:00725071380.014
sister chromatid segregationGO:0000819200.014
protein localization to nucleusGO:00345041210.014
chloride transportGO:0006821320.014
cellular chemical homeostasisGO:00550822150.014
amine metabolic processGO:0009308450.014
cellular respirationGO:0045333380.014
locomotory behaviorGO:00076261950.014
organelle fissionGO:00482851700.014
muscle system processGO:00030121410.013
nucleocytoplasmic transportGO:00069131390.013
phagocytosisGO:0006909660.013
external genitalia morphogenesisGO:003526110.013
histone deacetylationGO:0016575260.013
nucleosome positioningGO:001658440.013
jnk cascadeGO:0007254720.013
positive regulation of cell deathGO:00109422240.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
male gonad developmentGO:0008584880.013
positive regulation of histone methylationGO:0031062160.013
circulatory system processGO:00030131970.013
genitalia developmentGO:0048806370.012
nuclear transportGO:00511691390.012
stress activated mapk cascadeGO:0051403800.012
cation transportGO:00068123990.012
skeletal system developmentGO:00015013560.012
positive regulation of mitotic cell cycleGO:0045931410.012
regulation of chromatin modificationGO:1903308570.012
histone h3 k4 trimethylationGO:008018250.012
digestive tract developmentGO:00485651900.012
regulation of ion transportGO:00432692150.012
bone developmentGO:00603481200.012
sensory organ morphogenesisGO:00905962420.012
regulation of cellular component biogenesisGO:00440871810.012
organelle assemblyGO:00709251770.012
mitotic cell cycle processGO:19030471590.012
regulation of protein complex assemblyGO:0043254830.011
hepaticobiliary system developmentGO:0061008670.011
development of primary male sexual characteristicsGO:0046546880.011
dna alkylationGO:0006305430.011
regulation of embryonic developmentGO:0045995710.011
neurohypophysis developmentGO:002198520.011
negative regulation of immune system processGO:00026832090.011
epithelial tube morphogenesisGO:00605623030.011
cellular response to radiationGO:0071478280.011
synaptic vesicle transportGO:0048489570.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
regulation of cell migrationGO:00303342190.011
regulation of planar cell polarity pathway involved in axis elongationGO:200004030.011
neuron apoptotic processGO:00514021420.011
positive regulation of cell divisionGO:0051781310.011
protein processingGO:00164851630.011
rna catabolic processGO:0006401290.011
fat cell differentiationGO:00454441600.011
male gamete generationGO:00482322850.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
response to alcoholGO:0097305480.011
blood circulationGO:00080151950.011
meiotic sister chromatid segregationGO:004514460.011
regulation of kinase activityGO:00435492490.010
developmental maturationGO:00217001930.010
peptidyl lysine methylationGO:0018022290.010
erk1 and erk2 cascadeGO:0070371770.010
response to organic cyclic compoundGO:00140701980.010
synaptic vesicle localizationGO:0097479590.010
negative regulation of blood vessel morphogenesisGO:2000181250.010

Thoc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
bone development diseaseDOID:008000600.024
osteochondrodysplasiaDOID:225600.024
connective tissue diseaseDOID:6500.024
bone diseaseDOID:008000100.024
musculoskeletal system diseaseDOID:1700.024
long qt syndromeDOID:284300.017
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015