Mus musculus

0 known processes

Thoc4

THO complex 4

(Aliases: REF1,Refbp1,ALY)

Thoc4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of nucleotide catabolic processGO:003081290.716
Yeast
rna splicing via transesterification reactionsGO:0000375430.590
negative regulation of purine nucleotide catabolic processGO:003312290.541
Yeast
nucleic acid transportGO:0050657180.536
Human Yeast Mouse
mitotic cell cycle processGO:19030471590.508
mrna metabolic processGO:0016071840.439
positive regulation of dna templated transcription elongationGO:003278620.391
Human
establishment of rna localizationGO:0051236180.361
Human Yeast Mouse
rna transportGO:0050658180.353
Human Yeast Mouse
mrna processingGO:0006397630.343
regulation of mitotic cell cycleGO:00073461260.338
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.337
rna processingGO:00063961050.316
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.310
rna localizationGO:0006403230.280
Human Yeast Mouse
mitotic cell cycleGO:00002781950.278
negative regulation of purine nucleotide metabolic processGO:1900543160.249
Yeast
microtubule based processGO:00070172360.249
mrna splicing via spliceosomeGO:0000398430.228
mitotic centrosome separationGO:000710040.197
negative regulation of dna templated transcription terminationGO:006056710.192
dna repairGO:00062811070.191
Yeast
regulation of rna splicingGO:0043484370.190
regulation of mrna splicing via spliceosomeGO:0048024320.181
regulation of mrna metabolic processGO:1903311430.179
regulation of mrna processingGO:0050684410.176
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.169
microtubule cytoskeleton organizationGO:00002261570.168
oocyte constructionGO:000730820.160
regulation of hydrolase activityGO:00513362460.158
Yeast
rna splicingGO:0008380540.156
nucleobase containing compound transportGO:0015931270.151
Human Yeast Mouse
nuclear exportGO:0051168340.149
Human Yeast Mouse
development of primary sexual characteristicsGO:00451371430.147
nucleocytoplasmic transportGO:00069131390.137
Human Yeast Mouse
pole plasm assemblyGO:000731520.137
endocytosisGO:00068971680.135
oocyte anterior posterior axis specificationGO:000731420.126
negative regulation of nucleoside metabolic processGO:0045978110.125
Yeast
cellular nitrogen compound catabolic processGO:00442702800.125
Yeast
negative regulation of atpase activityGO:003278020.120
Yeast
transcription coupled nucleotide excision repairGO:000628320.114
Yeast
organelle fissionGO:00482851700.113
aromatic compound catabolic processGO:00194392860.110
Yeast
nuclear transportGO:00511691390.109
Human Yeast Mouse
negative regulation of phosphate metabolic processGO:00459361840.105
Yeast
nuclear divisionGO:00002801580.102
purine nucleotide catabolic processGO:00061952110.101
Yeast
regulation of protein complex disassemblyGO:0043244280.098
negative regulation of molecular functionGO:00440922580.094
Yeast
regulation of cell cycle processGO:00105641600.091
intracellular mrna localizationGO:000829840.089
regulation of purine nucleotide catabolic processGO:00331211220.088
Yeast
spermatogenesisGO:00072832840.087
negative regulation of cellular component organizationGO:00511291940.086
negative regulation of nucleotide metabolic processGO:0045980160.086
Yeast
oocyte axis specificationGO:000730920.086
dephosphorylationGO:00163111290.080
posttranscriptional regulation of gene expressionGO:00106081550.080
heterocycle catabolic processGO:00467002800.076
Yeast
establishment or maintenance of cytoskeleton polarityGO:003095220.071
purine nucleoside metabolic processGO:00422782410.068
Yeast
organic cyclic compound catabolic processGO:19013612950.065
Yeast
centrosome separationGO:005129940.064
negative regulation of hydrolase activityGO:0051346710.063
Yeast
dna metabolic processGO:00062593030.063
Human Yeast
alternative mrna splicing via spliceosomeGO:0000380120.061
positive regulation of cell cycleGO:0045787920.060
regulation of cellular catabolic processGO:00313292420.059
Yeast
regionalizationGO:00030023370.058
cellular response to dna damage stimulusGO:00069742070.058
Human Yeast
regulation of cell cycleGO:00517262810.058
nitrogen compound transportGO:00717052710.057
Human Yeast Mouse
ribose phosphate metabolic processGO:00196932910.057
Yeast
nucleoside catabolic processGO:00091642060.055
Yeast
poly a mrna export from nucleusGO:001697340.054
Mouse
segmentationGO:0035282930.054
nucleoside triphosphate metabolic processGO:00091412300.052
Yeast
ribonucleotide metabolic processGO:00092592910.050
Yeast
regulation of cellular component biogenesisGO:00440871810.050
mrna export from nucleusGO:0006406110.048
Human Yeast Mouse
negative regulation of atp metabolic processGO:190357940.048
Yeast
regulation of organelle organizationGO:00330432890.047
regulation of nucleotide catabolic processGO:00308111220.047
Yeast
striated muscle contractionGO:0006941450.047
organophosphate catabolic processGO:00464342320.047
Yeast
cellular macromolecule catabolic processGO:00442652060.046
nucleoside phosphate metabolic processGO:00067533380.046
Yeast
regulation of nucleotide metabolic processGO:00061401690.046
Yeast
oxidation reduction processGO:00551143420.046
regulation of nucleoside metabolic processGO:00091181300.045
Yeast
regulation of cell cycle phase transitionGO:1901987770.044
purine ribonucleoside metabolic processGO:00461282410.044
Yeast
response to organic cyclic compoundGO:00140701980.043
protein complex disassemblyGO:0043241400.041
positive regulation of cytoskeleton organizationGO:0051495490.041
cell divisionGO:00513011200.041
positive regulation of protein modification processGO:00314012990.041
germ cell developmentGO:00072811850.040
mitotic nuclear divisionGO:0007067480.039
regulation of translationGO:0006417710.039
negative regulation of cellular protein metabolic processGO:00322692470.038
nucleoside metabolic processGO:00091162460.038
Yeast
cellular amine metabolic processGO:0044106440.038
regulation of cell divisionGO:0051302760.038
amine metabolic processGO:0009308450.037
macromolecule catabolic processGO:00090572810.036
positive regulation of rna splicingGO:0033120120.035
dna templated transcription terminationGO:000635340.035
mrna transportGO:0051028130.035
Human Yeast Mouse
positive regulation of mrna metabolic processGO:1903313170.034
recombinational repairGO:0000725210.034
cell cycle checkpointGO:0000075470.033
intracellular protein transportGO:00068862040.033
cellular amino acid metabolic processGO:00065201030.032
nucleotide catabolic processGO:00091662170.032
Yeast
negative regulation of translationGO:0017148220.032
regulation of cellular amino acid metabolic processGO:000652150.032
nucleobase containing small molecule metabolic processGO:00550863520.032
Yeast
purine ribonucleotide metabolic processGO:00091502900.031
Yeast
response to organonitrogen compoundGO:00102432460.031
chromatin organizationGO:00063252060.030
positive regulation of cell cycle processGO:0090068610.030
regulation of dna templated transcription elongationGO:0032784100.030
Human
cytoplasmic transportGO:00164822340.030
Human Yeast Mouse
chromatin modificationGO:00165681870.030
translationGO:0006412930.029
positive regulation of glycogen catabolic processGO:004581920.029
cellular carbohydrate metabolic processGO:00442621190.029
negative regulation of immune system processGO:00026832090.028
adult behaviorGO:00305341350.028
protein import into nucleusGO:0006606950.028
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.027
rna export from nucleusGO:0006405150.027
Human Yeast Mouse
negative regulation of phagocytosisGO:005076540.027
positive regulation of organelle organizationGO:00106381280.027
polysaccharide metabolic processGO:0005976390.027
purine nucleoside triphosphate metabolic processGO:00091442260.026
Yeast
glucose homeostasisGO:00425931280.026
dna damage checkpointGO:0000077260.026
mrna catabolic processGO:0006402220.026
nuclear transcribed mrna catabolic processGO:0000956160.026
regulation of cellular response to stressGO:00801351590.026
regulation of dna damage checkpointGO:200000130.026
regulation of mitotic cell cycle phase transitionGO:1901990730.026
organonitrogen compound catabolic processGO:19015652640.025
Yeast
regulation of homeostatic processGO:00328441820.025
regulation of cellular amine metabolic processGO:0033238200.025
apoptotic signaling pathwayGO:00971903060.025
respiratory system developmentGO:00605411900.025
negative regulation of cell cycleGO:00457861230.025
regulation of atp metabolic processGO:1903578170.024
Yeast
generation of precursor metabolites and energyGO:00060911030.024
receptor mediated endocytosisGO:0006898510.024
negative regulation of protein complex disassemblyGO:0043242220.024
regulation of intracellular protein transportGO:0033157820.024
ribonucleoside monophosphate catabolic processGO:0009158570.024
Yeast
hematopoietic progenitor cell differentiationGO:00022441430.024
protein ubiquitinationGO:00165671710.023
leukocyte differentiationGO:00025213420.023
male gamete generationGO:00482322850.023
double strand break repairGO:0006302480.023
positive regulation of mitotic cell cycleGO:0045931410.023
regulation of multi organism processGO:00439001110.023
small gtpase mediated signal transductionGO:0007264970.023
ras protein signal transductionGO:0007265770.022
nuclear importGO:0051170950.022
dna templated transcription elongationGO:0006354130.022
Human
single fertilizationGO:0007338820.022
negative regulation of myeloid cell differentiationGO:0045638380.022
protein localization to nucleusGO:00345041210.022
muscle contractionGO:00069361010.022
spermatid differentiationGO:00485151150.022
cellular homeostasisGO:00197252400.022
positive regulation of mrna splicing via spliceosomeGO:0048026110.022
sensory perceptionGO:00076002450.021
rna dependent dna replicationGO:000627830.021
multicellular organism growthGO:00352641610.021
regulation of protein localizationGO:00328802310.021
gonad developmentGO:00084061410.021
purine nucleotide metabolic processGO:00061633020.021
Yeast
regulation of establishment of protein localizationGO:00702011810.021
nucleoside triphosphate catabolic processGO:00091432050.021
Yeast
histone modificationGO:00165701590.021
positive regulation of cellular catabolic processGO:00313311480.021
termination of rna polymerase ii transcriptionGO:000636910.020
maternal determination of anterior posterior axis embryoGO:000835820.020
ribonucleoside triphosphate catabolic processGO:00092031990.020
Yeast
regulation of double strand break repair via nonhomologous end joiningGO:200103220.020
multi multicellular organism processGO:00447061090.020
regulation of lymphocyte activationGO:00512492400.020
regulation of purine nucleotide metabolic processGO:19005421690.020
Yeast
purine nucleoside monophosphate metabolic processGO:0009126810.020
Yeast
regulation of ras protein signal transductionGO:00465781140.020
establishment or maintenance of cell polarityGO:0007163860.020
regulation of alternative mrna splicing via spliceosomeGO:000038180.020
cellular response to cytokine stimulusGO:00713451890.019
regulation of cell cycle checkpointGO:190197690.019
regulation of cellular ketone metabolic processGO:0010565660.019
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.018
fertilizationGO:00095661270.018
glycosyl compound metabolic processGO:19016572460.018
Yeast
spindle organizationGO:0007051280.018
stem cell differentiationGO:00488632680.018
cellular protein complex disassemblyGO:0043624360.018
cellular chemical homeostasisGO:00550822150.018
cardiac muscle contractionGO:0060048320.018
atp metabolic processGO:0046034750.018
Yeast
peptidyl amino acid modificationGO:00181933360.018
response to lipopolysaccharideGO:00324961280.018
lung developmentGO:00303241640.018
protein processingGO:00164851630.018
female gamete generationGO:0007292740.018
negative regulation of cell activationGO:00508661110.017
stem cell developmentGO:00488642190.017
regulation of apoptotic signaling pathwayGO:20012331970.017
genitalia developmentGO:0048806370.017
purine containing compound metabolic processGO:00725213110.017
Yeast
regulation of leukocyte differentiationGO:19021051590.017
protein localization to organelleGO:00333651850.017
nuclear mrna surveillanceGO:007102810.017
glycosyl compound catabolic processGO:19016582060.017
Yeast
digestive system developmentGO:00551232000.017
positive regulation of translationGO:0045727190.017
actin cytoskeleton organizationGO:00300362200.017
methylationGO:00322591340.017
monosaccharide metabolic processGO:00059961060.016
chemotaxisGO:00069352470.016
nucleoside monophosphate catabolic processGO:0009125590.016
Yeast
ion transmembrane transportGO:00342203610.016
striated muscle myosin thick filament assemblyGO:007168810.016
positive regulation of cell cycle phase transitionGO:1901989170.016
muscle tissue developmentGO:00605373080.016
carbohydrate homeostasisGO:00335001280.016
chromatin assemblyGO:0031497130.015
atp catabolic processGO:0006200550.015
Yeast
cellular response to carbohydrate stimulusGO:0071322500.015
protein targetingGO:00066051430.015
carbohydrate metabolic processGO:00059752300.015
energy derivation by oxidation of organic compoundsGO:0015980770.015
positive regulation of cellular amine metabolic processGO:003324050.015
purine ribonucleoside monophosphate catabolic processGO:0009169570.015
Yeast
regulation of cell migrationGO:00303342190.015
regulation of vesicle mediated transportGO:00606271390.015
regulation of cytoskeleton organizationGO:00514931220.015
hexose metabolic processGO:0019318980.015
positive regulation of dna repairGO:004573930.015
regulation of double strand break repair via homologous recombinationGO:001056920.014
homeostasis of number of cellsGO:00488722100.014
stem cell maintenanceGO:00198271300.014
regulation of mrna stabilityGO:0043488230.014
regulation of lymphocyte differentiationGO:00456191070.014
covalent chromatin modificationGO:00165691630.014
organelle assemblyGO:00709251770.014
cell type specific apoptotic processGO:00972852680.014
epithelial tube morphogenesisGO:00605623030.014
reactive oxygen species metabolic processGO:0072593840.014
purine nucleoside monophosphate catabolic processGO:0009128580.014
Yeast
ribonucleoside catabolic processGO:00424542060.014
Yeast
glycogen metabolic processGO:0005977320.014
cell cycle g1 s phase transitionGO:0044843570.014
camera type eye developmentGO:00430102660.014
protein maturationGO:00516041760.014
ribonucleoside metabolic processGO:00091192450.014
Yeast
spermatid developmentGO:00072861080.013
mapk cascadeGO:00001652810.013
respiratory tube developmentGO:00303231670.013
protein modification by small protein conjugation or removalGO:00706472070.013
regulation of intracellular transportGO:00323861590.013
regulation of transferase activityGO:00513382630.013
purine ribonucleoside catabolic processGO:00461302050.013
Yeast
regulation of cell motilityGO:20001452360.013
regulation of cell activationGO:00508652890.013
meiotic cell cycle checkpointGO:003331320.013
membrane organizationGO:00610242450.013
ear developmentGO:00435832000.013
developmental maturationGO:00217001930.013
striated muscle tissue developmentGO:00147062930.013
nucleus organizationGO:0006997450.013
chromatin assembly or disassemblyGO:0006333160.013
compound eye developmentGO:004874910.013
cellular glucan metabolic processGO:0006073320.013
double strand break repair via nonhomologous end joiningGO:0006303100.013
response to acid chemicalGO:00011011110.013
positive regulation of cell divisionGO:0051781310.013
myeloid cell differentiationGO:00300992330.013
cellular response to hexose stimulusGO:0071331470.013
cell adhesionGO:00071553290.013
cellular polysaccharide metabolic processGO:0044264380.013
regulation of mapk cascadeGO:00434082480.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
Yeast
negative regulation of leukocyte differentiationGO:1902106510.012
cellular response to acid chemicalGO:0071229680.012
cellular ketone metabolic processGO:0042180840.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
Yeast
ossificationGO:00015032160.012
Human
organelle localizationGO:00516401790.012
nucleotide metabolic processGO:00091173320.012
Yeast
double strand break repair via homologous recombinationGO:0000724210.012
negative regulation of protein metabolic processGO:00512482820.012
placenta developmentGO:00018901400.012
positive regulation of intracellular transportGO:0032388700.012
skin developmentGO:00435882200.012
regulation of cellular carbohydrate metabolic processGO:0010675750.012
positive regulation of hydrolase activityGO:00513451480.012
blastoderm segmentationGO:0007350130.012
negative regulation of phosphorus metabolic processGO:00105631840.012
Yeast
single organism nuclear importGO:1902593950.012
chromosome segregationGO:0007059480.012
macromolecular complex disassemblyGO:0032984430.012
regulation of chromatin modificationGO:1903308570.012
connective tissue developmentGO:00614481790.012
cellular response to hormone stimulusGO:00328701500.012
regulation of cell cycle g1 s phase transitionGO:1902806350.011
modification dependent macromolecule catabolic processGO:00436321330.011
circulatory system processGO:00030131970.011
regulation of embryonic developmentGO:0045995710.011
regulation of rna stabilityGO:0043487260.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
nucleoside phosphate catabolic processGO:19012922220.011
Yeast
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
Yeast
cation transportGO:00068123990.011
cellular response to organonitrogen compoundGO:00714171450.011
transcription elongation from rna polymerase ii promoterGO:000636890.011
transmembrane transportGO:00550854120.011
dna integrity checkpointGO:0031570280.011
regulation of protein import into nucleusGO:0042306520.011
negative regulation of mitotic cell cycleGO:0045930580.011
protein importGO:00170381010.011
mitotic cell cycle checkpointGO:0007093310.011
b cell activationGO:00421131610.011
regulation of nuclear divisionGO:0051783560.011
positive regulation of transferase activityGO:00513471670.011
regulation of secretion by cellGO:19035302490.011
muscle cell differentiationGO:00426922610.011
megakaryocyte differentiationGO:0030219260.011
protein dna complex subunit organizationGO:0071824280.011
positive regulation of keratinocyte proliferationGO:001083840.011
regulation of response to dna damage stimulusGO:2001020340.011
positive regulation of mrna processingGO:0050685160.010
positive regulation of cell deathGO:00109422240.010
myosin filament assemblyGO:003103420.010
negative regulation of apoptotic cell clearanceGO:200042610.010
maternal process involved in female pregnancyGO:0060135320.010
lymphocyte differentiationGO:00300982420.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.010
carbohydrate derivative biosynthetic processGO:19011371830.010
regulation of nucleocytoplasmic transportGO:0046822730.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.010

Thoc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012
colorectal cancerDOID:925600.011
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
intestinal cancerDOID:1015500.011
gastrointestinal system cancerDOID:311900.011
large intestine cancerDOID:567200.011
colon cancerDOID:21900.011