Mus musculus

23 known processes

Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

(Aliases: IkB,IKB-beta,MGC36057,IkBb,IKappaBbeta)

Nfkbib biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201030.141
response to organonitrogen compoundGO:00102432460.102
Mouse
leukocyte differentiationGO:00025213420.093
Mouse
cellular amine metabolic processGO:0044106440.084
lymphocyte differentiationGO:00300982420.079
Mouse
regulation of cellular amino acid metabolic processGO:000652150.076
positive regulation of cellular amine metabolic processGO:003324050.075
protein catabolic processGO:00301632210.070
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.067
Mouse
protein modification by small protein conjugationGO:00324461870.066
negative regulation of protein metabolic processGO:00512482820.065
Mouse
immune effector processGO:00022523210.064
Mouse Fly
apoptotic signaling pathwayGO:00971903060.061
negative regulation of molecular functionGO:00440922580.060
response to peptideGO:19016521360.059
Mouse
t cell activationGO:00421102890.059
Mouse
t cell differentiationGO:00302171740.059
Mouse
response to peptide hormoneGO:00434341270.058
regulation of cellular amine metabolic processGO:0033238200.058
negative regulation of intracellular signal transductionGO:19025321670.054
Rat
regulation of antimicrobial humoral responseGO:000275930.054
Fly
antimicrobial peptide productionGO:000277520.053
Fly
innate immune responseGO:00450871570.051
Mouse
response to molecule of bacterial originGO:00022371430.051
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.050
regulation of cellular ketone metabolic processGO:0010565660.050
amine metabolic processGO:0009308450.048
modification dependent macromolecule catabolic processGO:00436321330.048
regulation of lymphocyte differentiationGO:00456191070.046
peptidyl amino acid modificationGO:00181933360.045
positive regulation of cellular amino acid metabolic processGO:004576430.045
cellular amide metabolic processGO:0043603580.043
Fly
cellular response to peptide hormone stimulusGO:0071375920.042
myeloid leukocyte differentiationGO:00025731190.042
regulation of neuron deathGO:19012141340.041
camera type eye developmentGO:00430102660.041
positive regulation of apoptotic processGO:00430652170.041
cellular response to hormone stimulusGO:00328701500.040
peptide metabolic processGO:0006518460.040
Fly
chromatin organizationGO:00063252060.039
cytokine productionGO:00018163190.038
Mouse
positive regulation of protein phosphorylationGO:00019342420.038
cellular ketone metabolic processGO:0042180840.038
gland developmentGO:00487323300.037
mapk cascadeGO:00001652810.036
positive regulation of protein modification processGO:00314012990.036
protein ubiquitinationGO:00165671710.035
protein targetingGO:00066051430.035
Mouse Rat
small gtpase mediated signal transductionGO:0007264970.035
germinal center formationGO:0002467160.035
Mouse
organonitrogen compound biosynthetic processGO:19015661920.034
Fly
sensory organ morphogenesisGO:00905962420.034
t cell differentiation in thymusGO:0033077770.034
response to lipopolysaccharideGO:00324961280.034
purine ribonucleotide metabolic processGO:00091502900.034
cellular response to lipopolysaccharideGO:0071222770.033
macromolecule catabolic processGO:00090572810.033
response to inorganic substanceGO:0010035960.033
regulation of leukocyte differentiationGO:19021051590.032
positive regulation of programmed cell deathGO:00430682180.032
chromatin modificationGO:00165681870.032
positive regulation of antimicrobial peptide productionGO:000222510.032
Fly
negative regulation of phosphorus metabolic processGO:00105631840.031
regulation of cytokine productionGO:00018172660.031
Mouse
regulation of defense response to bacteriumGO:190042430.031
gonad developmentGO:00084061410.030
positive regulation of cell deathGO:00109422240.030
cellular response to organonitrogen compoundGO:00714171450.030
protein modification by small protein conjugation or removalGO:00706472070.030
regulation of transferase activityGO:00513382630.030
protein localization to membraneGO:00726571080.030
heterocycle catabolic processGO:00467002800.030
regulation of lymphocyte activationGO:00512492400.029
regionalizationGO:00030023370.029
Fly
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.029
Fly
cellular response to dna damage stimulusGO:00069742070.029
Fly
covalent chromatin modificationGO:00165691630.029
regulation of antimicrobial peptide productionGO:000278410.027
Fly
cellular response to cytokine stimulusGO:00713451890.027
regulation of defense responseGO:00313472330.027
Mouse Fly
molting cycleGO:0042303900.027
cellular response to peptideGO:1901653920.027
regulation of sequence specific dna binding transcription factor activityGO:00510901060.027
regulation of antimicrobial peptide biosynthetic processGO:000280510.027
Fly
regulation of cell cycleGO:00517262810.027
purine containing compound metabolic processGO:00725213110.027
glycosyl compound metabolic processGO:19016572460.027
myeloid cell differentiationGO:00300992330.026
Mouse
spermatogenesisGO:00072832840.026
neuron deathGO:00709971540.026
histone modificationGO:00165701590.026
response to oxidative stressGO:00069791230.026
positive regulation of defense responseGO:00313491240.026
Mouse Fly
response to radiationGO:00093141650.026
glycosyl compound catabolic processGO:19016582060.026
modification dependent protein catabolic processGO:00199411330.025
negative regulation of cellular amino acid metabolic processGO:004576300.025
negative regulation of neuron deathGO:1901215980.025
regulation of inflammatory responseGO:00507271470.025
purine nucleotide metabolic processGO:00061633020.025
regulation of t cell differentiationGO:0045580830.024
rhythmic processGO:00485111740.024
response to organic cyclic compoundGO:00140701980.024
Mouse
cytokine metabolic processGO:0042107710.024
Mouse
regulation of kinase activityGO:00435492490.024
purine nucleotide catabolic processGO:00061952110.023
negative regulation of protein modification processGO:00314001630.023
ribonucleoside triphosphate metabolic processGO:00091992200.023
regulation of innate immune responseGO:0045088910.023
Mouse
striated muscle tissue developmentGO:00147062930.023
regulation of protein kinase activityGO:00458592320.023
protein localization to organelleGO:00333651850.023
Mouse Rat
development of primary sexual characteristicsGO:00451371430.023
g protein coupled receptor signaling pathwayGO:00071862430.023
negative regulation of phosphorylationGO:00423261660.023
multicellular organismal signalingGO:0035637910.022
regulation of mapk cascadeGO:00434082480.022
negative regulation of cellular protein metabolic processGO:00322692470.022
cellular macromolecule catabolic processGO:00442652060.022
negative regulation of immune system processGO:00026832090.022
Mouse
skin developmentGO:00435882200.021
purine ribonucleoside triphosphate metabolic processGO:00092052200.021
germ cell developmentGO:00072811850.021
Fly
alpha beta t cell differentiationGO:0046632690.021
Mouse
ras protein signal transductionGO:0007265770.021
regulation of ion transportGO:00432692150.020
regulation of multi organism processGO:00439001110.020
Fly
connective tissue developmentGO:00614481790.020
reactive oxygen species metabolic processGO:0072593840.020
lung developmentGO:00303241640.020
spermatid differentiationGO:00485151150.020
intracellular receptor signaling pathwayGO:0030522740.020
Mouse
membrane organizationGO:00610242450.020
regulation of reactive oxygen species biosynthetic processGO:190342620.020
cellular response to biotic stimulusGO:0071216920.019
rna processingGO:00063961050.019
cellular protein catabolic processGO:00442571550.019
maintenance of locationGO:0051235890.019
Rat
regulation of cell activationGO:00508652890.019
intracellular protein transportGO:00068862040.019
Mouse Rat
epithelial cell developmentGO:00020641590.019
Fly
meiotic nuclear divisionGO:00071261150.019
negative regulation of phosphate metabolic processGO:00459361840.019
regulation of membrane potentialGO:00423911920.019
epidermis developmentGO:00085441870.019
cellular chemical homeostasisGO:00550822150.018
blood circulationGO:00080151950.018
locomotory behaviorGO:00076261950.018
mrna metabolic processGO:0016071840.018
cellular response to lipidGO:00713961450.018
purine nucleoside triphosphate catabolic processGO:00091462030.018
peptidyl serine modificationGO:0018209830.018
nuclear transportGO:00511691390.018
Mouse Rat
adaptive immune responseGO:00022501550.018
Mouse
sequestering of calcium ionGO:0051208180.018
embryonic organ morphogenesisGO:00485622760.018
ribonucleoside metabolic processGO:00091192450.018
nucleoside triphosphate metabolic processGO:00091412300.018
purine nucleoside metabolic processGO:00422782410.018
response to acid chemicalGO:00011011110.018
establishment of protein localization to organelleGO:00725941180.018
Mouse Rat
production of molecular mediator of immune responseGO:00024401030.018
Fly
cell type specific apoptotic processGO:00972852680.018
antigen processing and presentationGO:0019882470.017
carbohydrate derivative biosynthetic processGO:19011371830.017
regulation of organelle organizationGO:00330432890.017
purine ribonucleoside metabolic processGO:00461282410.017
carbohydrate metabolic processGO:00059752300.017
regulation of antibacterial peptide biosynthetic processGO:000280810.017
cellular response to molecule of bacterial originGO:0071219830.017
positive regulation of kinase activityGO:00336741550.017
regulation of bindingGO:00510981110.017
male sex differentiationGO:00466611090.017
regulation of hormone levelsGO:00108172110.017
synaptic transmissionGO:00072683290.017
negative regulation of apoptotic signaling pathwayGO:20012341040.017
female gonad developmentGO:0008585710.017
ribose phosphate metabolic processGO:00196932910.017
nucleoside triphosphate catabolic processGO:00091432050.016
male gamete generationGO:00482322850.016
glycoprotein metabolic processGO:00091001160.016
defense response to bacteriumGO:00427421190.016
Mouse
post embryonic retina morphogenesis in camera type eyeGO:006006030.016
hair cycleGO:0042633900.016
embryonic placenta developmentGO:0001892980.016
aromatic compound catabolic processGO:00194392860.016
cation transportGO:00068123990.016
positive regulation of antibacterial peptide biosynthetic processGO:000696310.016
muscle tissue developmentGO:00605373080.016
neuron apoptotic processGO:00514021420.016
development of primary male sexual characteristicsGO:0046546880.016
posttranscriptional regulation of gene expressionGO:00106081550.016
cellular response to organic cyclic compoundGO:0071407870.016
purine containing compound catabolic processGO:00725232130.016
lymphocyte activation involved in immune responseGO:0002285930.016
Mouse
compound eye developmentGO:004874910.016
cellular nitrogen compound catabolic processGO:00442702800.016
positive regulation of protein kinase activityGO:00458601440.016
activation of innate immune responseGO:0002218560.016
Mouse
inflammatory responseGO:00069542440.015
negative regulation of cellular amine metabolic processGO:003323910.015
spleen developmentGO:0048536390.015
Mouse
positive regulation of cytokine productionGO:00018191740.015
Mouse
development of primary female sexual characteristicsGO:0046545730.015
rna interferenceGO:001624620.015
nitrogen compound transportGO:00717052710.015
Rat
protein importGO:00170381010.015
Mouse Rat
divalent inorganic cation transportGO:00725111780.015
negative regulation of response to woundingGO:1903035770.015
regulation of t cell activationGO:00508631700.015
ovarian follicle developmentGO:0001541400.015
retina development in camera type eyeGO:00600411190.015
activation of immune responseGO:00022531380.015
Mouse
cell adhesionGO:00071553290.015
tumor necrosis factor productionGO:0032640500.015
Mouse
cytokine biosynthetic processGO:0042089680.015
Mouse
organelle fissionGO:00482851700.015
mrna splicing via spliceosomeGO:0000398430.015
cellular homeostasisGO:00197252400.015
ear developmentGO:00435832000.015
positive regulation of antimicrobial humoral responseGO:000276020.015
Fly
lens development in camera type eyeGO:0002088620.015
respiratory tube developmentGO:00303231670.015
reactive oxygen species biosynthetic processGO:190340980.015
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.015
Mouse
regulation of mitotic cell cycleGO:00073461260.015
regulation of response to woundingGO:19030341890.015
nucleotide metabolic processGO:00091173320.015
regulation of protein targetingGO:1903533610.015
Rat
positive regulation of hydrolase activityGO:00513451480.015
ribonucleotide metabolic processGO:00092592910.014
regulation of intracellular protein transportGO:0033157820.014
Rat
regulation of peptide transportGO:0090087910.014
Rat
positive regulation of mirna metabolic processGO:200063010.014
female sex differentiationGO:0046660840.014
cellular protein complex assemblyGO:00436231160.014
interferon gamma productionGO:0032609670.014
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.014
regulation of cytoplasmic transportGO:19036491120.014
Rat
regulation of neuron apoptotic processGO:00435231220.014
regulation of purine nucleotide metabolic processGO:19005421690.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
Mouse
regulation of protein catabolic processGO:00421761080.014
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.014
Mouse
male gonad developmentGO:0008584880.014
nucleobase containing small molecule metabolic processGO:00550863520.014
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.014
peptidyl serine phosphorylationGO:0018105740.014
positive regulation of innate immune responseGO:0045089800.014
Mouse
regulation of secretion by cellGO:19035302490.014
ossificationGO:00015032160.014
alpha beta t cell differentiation involved in immune responseGO:0002293300.013
Mouse
regulation of establishment of protein localizationGO:00702011810.013
Rat
regulation of transmembrane transportGO:00347621280.013
positive regulation of growth hormone receptor signaling pathwayGO:006039930.013
organic cyclic compound catabolic processGO:19013612950.013
placenta developmentGO:00018901400.013
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.013
regulation of protein serine threonine kinase activityGO:00719001570.013
endomembrane system organizationGO:00102561470.013
organic hydroxy compound metabolic processGO:19016152030.013
positive regulation of proteolysisGO:0045862850.013
organonitrogen compound catabolic processGO:19015652640.013
stem cell differentiationGO:00488632680.013
i kappab kinase nf kappab signalingGO:0007249850.013
Rat
antibacterial peptide productionGO:000277820.013
developmental maturationGO:00217001930.013
response to copper ionGO:004668830.013
regulation of cell migrationGO:00303342190.013
regulation of protein transportGO:00512231630.013
Rat
regulation of defense response to fungusGO:190015010.013
Fly
regulation of anatomical structure sizeGO:00900661780.013
hair follicle developmentGO:0001942850.013
rna splicingGO:0008380540.013
response to light stimulusGO:00094161350.013
protein polyubiquitinationGO:0000209330.013
nuclear importGO:0051170950.013
Mouse Rat
hepaticobiliary system developmentGO:0061008670.013
notch signaling pathwayGO:0007219710.012
Mouse
regulation of intracellular transportGO:00323861590.012
Rat
regulation of antibacterial peptide productionGO:000278610.012
multicellular organism growthGO:00352641610.012
cell growthGO:00160491300.012
regulation of striated muscle cell differentiationGO:0051153810.012
extracellular structure organizationGO:00430621480.012
Mouse
negative regulation of defense responseGO:0031348770.012
cellular metal ion homeostasisGO:00068751510.012
transmembrane transportGO:00550854120.012
peptidyl tyrosine phosphorylationGO:00181081430.012
nucleoside phosphate metabolic processGO:00067533380.012
positive regulation of transferase activityGO:00513471670.012
positive regulation of cellular catabolic processGO:00313311480.012
antibacterial peptide biosynthetic processGO:000278020.012
negative regulation of neuron apoptotic processGO:0043524920.012
dna metabolic processGO:00062593030.012
cell maturationGO:00484691270.012
mrna processingGO:0006397630.012
protein maturationGO:00516041760.012
myeloid cell homeostasisGO:00022621140.012
purine ribonucleoside catabolic processGO:00461302050.012
steroid metabolic processGO:00082021190.012
purine ribonucleotide catabolic processGO:00091542080.012
regulation of mrna metabolic processGO:1903311430.012
circadian rhythmGO:00076231140.012
defense response to other organismGO:00985421970.012
Mouse Fly
cellular lipid metabolic processGO:00442553230.012
myeloid leukocyte activationGO:0002274830.012
b cell activationGO:00421131610.012
Mouse
positive regulation of mapk cascadeGO:00434101700.012
divalent metal ion transportGO:00708381720.012
nucleoside phosphate catabolic processGO:19012922220.012
regulation of cytokine biosynthetic processGO:0042035590.011
Mouse
cellular carbohydrate metabolic processGO:00442621190.011
skeletal system morphogenesisGO:00487052030.011
muscle cell differentiationGO:00426922610.011
protein polymerizationGO:0051258570.011
positive regulation of production of molecular mediator of immune responseGO:0002702450.011
Fly
regulation of metal ion transportGO:00109591060.011
positive regulation of cytokine biosynthetic processGO:0042108400.011
Mouse
response to growth factorGO:00708481980.011
carbohydrate biosynthetic processGO:0016051740.011
extracellular matrix organizationGO:00301981470.011
Mouse
innate immune response activating signal transductionGO:0002758500.011
Mouse
purine nucleoside triphosphate metabolic processGO:00091442260.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
regulation of mirna metabolic processGO:200062840.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
ovulation cycleGO:0042698590.011
nucleoside catabolic processGO:00091642060.011
circadian regulation of gene expressionGO:0032922480.011
negative regulation of protein phosphorylationGO:00019331260.011
glucose homeostasisGO:00425931280.011
nucleoside monophosphate metabolic processGO:0009123850.011
ion transmembrane transportGO:00342203610.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
skeletal system developmentGO:00015013560.011
adult behaviorGO:00305341350.011
nik nf kappab signalingGO:0038061140.011
positive regulation of growthGO:00459271040.011
mitotic cell cycleGO:00002781950.011
nucleocytoplasmic transportGO:00069131390.011
Mouse Rat
response to interleukin 6GO:0070741100.011
negative regulation of cell proliferationGO:00082852960.011
humoral immune responseGO:0006959570.010
Mouse Fly
vitamin d biosynthetic processGO:004236830.010
microtubule based processGO:00070172360.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.010
oxidation reduction processGO:00551143420.010
positive regulation of purine nucleotide metabolic processGO:19005441140.010
liver developmentGO:0001889660.010
wnt signaling pathwayGO:00160551880.010
metal ion homeostasisGO:00550651890.010
myosin filament organizationGO:003103330.010
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.010
Mouse
b cell differentiationGO:0030183780.010
Mouse
response to reactive oxygen speciesGO:0000302560.010
cd4 positive alpha beta t cell differentiationGO:0043367410.010
Mouse
response to oxygen levelsGO:0070482620.010
glycoprotein biosynthetic processGO:0009101890.010
carbohydrate derivative catabolic processGO:19011362310.010
regulation of interferon gamma productionGO:0032649570.010
Mouse
microtubule cytoskeleton organizationGO:00002261570.010
homeostasis of number of cellsGO:00488722100.010
tumor necrosis factor superfamily cytokine productionGO:0071706510.010
Mouse
respiratory system developmentGO:00605411900.010

Nfkbib disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.016
immune system diseaseDOID:291400.015
hematopoietic system diseaseDOID:7400.015
disease of metabolismDOID:001466700.014