Mus musculus

90 known processes

Chuk

conserved helix-loop-helix ubiquitous kinase

(Aliases: IKK1,AI256658,Fbx24,MGC25325,IKBKA,Ikka,Fbxo24,NFKBIKA,Chuk1)

Chuk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
serine phosphorylation of stat proteinGO:004250131.000
dendritic cell proliferationGO:004456520.999
Mouse
regulation of antibacterial peptide productionGO:000278610.994
Fly
interferon beta biosynthetic processGO:004535040.992
Mouse
i kappab phosphorylationGO:000725260.989
Mouse
regulation of interferon beta biosynthetic processGO:004535740.984
Mouse
activation of nf kappab inducing kinase activityGO:000725040.929
activation of innate immune responseGO:0002218560.929
Mouse
positive regulation of ion transmembrane transporter activityGO:0032414150.921
Mouse
homeostasis of number of cellsGO:00488722100.912
Mouse
myeloid cell differentiationGO:00300992330.903
positive regulation of antibacterial peptide biosynthetic processGO:000696310.891
Fly
regulation of cellular component biogenesisGO:00440871810.891
positive regulation of interferon beta productionGO:003272880.887
Mouse
response to endoplasmic reticulum stressGO:0034976530.874
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.872
skeletal system developmentGO:00015013560.851
epithelial cell proliferationGO:00506731740.846
positive regulation of innate immune responseGO:0045089800.830
Mouse
axonogenesisGO:00074092740.806
mammary gland lobule developmentGO:0061377220.793
myeloid leukocyte differentiationGO:00025731190.792
regulation of ion transmembrane transportGO:00347651190.764
Mouse
interferon beta productionGO:0032608160.747
Mouse
organonitrogen compound biosynthetic processGO:19015661920.743
Fly
regionalizationGO:00030023370.743
Zebrafish
positive regulation of interferon beta biosynthetic processGO:004535930.693
Mouse
regulation of antibacterial peptide biosynthetic processGO:000280810.684
Fly
odontogenesis of dentin containing toothGO:0042475660.663
regulation of defense responseGO:00313472330.644
Mouse Fly
mammary gland alveolus developmentGO:0060749220.627
regulation of sequence specific dna binding transcription factor activityGO:00510901060.616
regulation of body fluid levelsGO:00508781620.608
i kappab kinase nf kappab signalingGO:0007249850.606
regulation of innate immune responseGO:0045088910.585
Mouse Fly
gland developmentGO:00487323300.564
gastrulationGO:00073691160.555
Zebrafish
osteoclast differentiationGO:0030316620.549
antibacterial peptide productionGO:000277820.537
Fly
embryonic skeletal system developmentGO:00487061200.527
developmental maturationGO:00217001930.518
morphogenesis of embryonic epitheliumGO:00163311590.496
type i interferon biosynthetic processGO:004535190.486
Mouse
negative regulation of cellular amine metabolic processGO:003323910.458
positive regulation of cytokine productionGO:00018191740.450
Mouse
regulation of establishment of protein localizationGO:00702011810.444
cellular protein catabolic processGO:00442571550.440
negative regulation of dna replicationGO:000815640.432
defense response to other organismGO:00985421970.426
Mouse Fly
macromolecule catabolic processGO:00090572810.412
Fly
negative regulation of molecular functionGO:00440922580.409
embryonic epithelial tube formationGO:00018381300.399
regulation of cation channel activityGO:2001257220.393
Mouse
embryonic limb morphogenesisGO:00303261260.388
respiratory tube developmentGO:00303231670.386
positive regulation of ion transmembrane transportGO:0034767240.384
Mouse
modification dependent macromolecule catabolic processGO:00436321330.377
striated muscle contractionGO:0006941450.370
purine ribonucleoside metabolic processGO:00461282410.369
regulation of kinase activityGO:00435492490.364
angiogenesisGO:00015252010.349
protein catabolic processGO:00301632210.348
Fly
positive regulation of apoptotic processGO:00430652170.346
regulation of cellular amino acid metabolic processGO:000652150.343
regulation of cell morphogenesis involved in differentiationGO:00107691510.341
circulatory system processGO:00030131970.329
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathwayGO:1902235110.326
regulation of neuron differentiationGO:00456642810.324
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.321
Fly
embryonic skeletal system morphogenesisGO:0048704910.314
negative regulation of growthGO:0045926990.307
regulation of neuron projection developmentGO:00109751690.301
intracellular protein transportGO:00068862040.300
type i interferon productionGO:0032606290.293
Mouse
peptide metabolic processGO:0006518460.291
Fly
purine containing compound metabolic processGO:00725213110.290
mammary gland epithelium developmentGO:0061180650.287
antimicrobial peptide productionGO:000277520.283
Fly
ion transmembrane transportGO:00342203610.282
Mouse
synaptic vesicle localizationGO:0097479590.279
appendage morphogenesisGO:00351071490.275
regulation of protein kinase activityGO:00458592320.275
organonitrogen compound catabolic processGO:19015652640.273
leukocyte differentiationGO:00025213420.272
skin developmentGO:00435882200.271
regulation of cytokine biosynthetic processGO:0042035590.270
Mouse
purine ribonucleotide metabolic processGO:00091502900.268
positive regulation of proteolysisGO:0045862850.265
b cell homeostasisGO:0001782340.262
Mouse
positive regulation of sodium ion transportGO:0010765130.261
Mouse
regulation of organ morphogenesisGO:20000271440.259
positive regulation of antimicrobial humoral responseGO:000276020.255
Fly
cellular homeostasisGO:00197252400.252
glycosyl compound metabolic processGO:19016572460.252
blood circulationGO:00080151950.250
embryonic organ morphogenesisGO:00485622760.250
lactationGO:0007595250.248
positive regulation of defense response to bacteriumGO:190042610.247
Fly
protein targetingGO:00066051430.243
chemotaxisGO:00069352470.239
asymmetric neuroblast divisionGO:005505910.236
activation of immune responseGO:00022531380.235
Mouse
aromatic compound catabolic processGO:00194392860.235
regulation of metal ion transportGO:00109591060.234
Mouse
neuron projection guidanceGO:00974851410.229
purine nucleotide metabolic processGO:00061633020.228
peptidyl amino acid modificationGO:00181933360.226
Fly
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.226
epithelial tube morphogenesisGO:00605623030.225
morphogenesis of an epithelial sheetGO:0002011270.224
positive regulation of cellular catabolic processGO:00313311480.221
peptidyl serine modificationGO:0018209830.218
Fly
negative regulation of protein phosphorylationGO:00019331260.214
positive regulation of cytokine biosynthetic processGO:0042108400.213
Mouse
genetic imprintingGO:0071514270.210
protein modification by small protein conjugation or removalGO:00706472070.208
lipid localizationGO:00108761260.206
neuron apoptotic processGO:00514021420.205
muscle contractionGO:00069361010.205
regulation of cytokine productionGO:00018172660.204
Mouse
negative regulation of necroptotic processGO:006054690.204
positive regulation of secretionGO:00510471300.203
wnt signaling pathwayGO:00160551880.202
ossificationGO:00015032160.202
regulation of cellular ketone metabolic processGO:0010565660.193
regulation of synaptic growth at neuromuscular junctionGO:000858240.192
carbohydrate derivative catabolic processGO:19011362310.191
positive regulation of protein serine threonine kinase activityGO:00719021060.191
protein modification by small protein conjugationGO:00324461870.190
regulation of cell projection organizationGO:00313442060.189
primary neural tube formationGO:0014020950.187
respiratory system developmentGO:00605411900.186
dna metabolic processGO:00062593030.186
negative regulation of cell proliferationGO:00082852960.184
proteolysis involved in cellular protein catabolic processGO:00516031470.183
negative regulation of apoptotic signaling pathwayGO:20012341040.183
cellular ketone metabolic processGO:0042180840.182
cellular nitrogen compound catabolic processGO:00442702800.181
mammary gland epithelial cell proliferationGO:0033598240.180
negative regulation of protein modification processGO:00314001630.179
synaptic transmissionGO:00072683290.178
regulation of cell cycleGO:00517262810.176
cellularizationGO:000734910.176
transmembrane transportGO:00550854120.173
Mouse
appendage developmentGO:00487361660.171
regulation of reactive oxygen species metabolic processGO:2000377400.170
neurotransmitter secretionGO:0007269620.169
neuron deathGO:00709971540.166
regulation of neurotransmitter levelsGO:0001505870.165
epithelial tube formationGO:00721751300.165
actin cytoskeleton organizationGO:00300362200.163
regulation of cell motilityGO:20001452360.162
lung developmentGO:00303241640.162
body fluid secretionGO:0007589530.160
purine ribonucleotide catabolic processGO:00091542080.159
cellular amine metabolic processGO:0044106440.157
skeletal system morphogenesisGO:00487052030.156
apoptotic signaling pathwayGO:00971903060.153
cytokine metabolic processGO:0042107710.152
Mouse
cellular metal ion homeostasisGO:00068751510.152
response to nutrient levelsGO:00316671090.151
nitrogen compound transportGO:00717052710.151
mitochondrion organizationGO:00070051340.151
muscle cell proliferationGO:0033002520.147
regulation of cellular component sizeGO:00325351210.147
dendrite developmentGO:00163581150.144
cellular macromolecule catabolic processGO:00442652060.143
response to oxidative stressGO:00069791230.141
nucleoside phosphate metabolic processGO:00067533380.139
carbon catabolite regulation of transcriptionGO:004599040.138
cytokine productionGO:00018163190.138
Mouse
action potentialGO:0001508780.138
organelle localizationGO:00516401790.136
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.136
neuronal action potentialGO:0019228540.136
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.136
regulation of cellular amine metabolic processGO:0033238200.135
organophosphate catabolic processGO:00464342320.134
ripoptosome assembly involved in necroptotic processGO:190102660.133
positive regulation of kinase activityGO:00336741550.133
single organism cell adhesionGO:00986021560.133
regulation of anatomical structure sizeGO:00900661780.133
regulation of protein serine threonine kinase activityGO:00719001570.132
positive regulation of ion transportGO:0043270650.131
Mouse
regulation of defense response to bacteriumGO:190042430.130
Fly
regulation of membrane potentialGO:00423911920.130
positive regulation of mitotic cell cycle phase transitionGO:1901992170.129
positive regulation of defense responseGO:00313491240.129
Mouse Fly
embryonic appendage morphogenesisGO:00351131260.127
organic cyclic compound catabolic processGO:19013612950.126
ribonucleotide metabolic processGO:00092592910.125
regulation of organelle organizationGO:00330432890.125
bone developmentGO:00603481200.125
odontogenesisGO:0042476780.124
blood vessel morphogenesisGO:00485142850.124
negative regulation of epithelial cell proliferationGO:0050680640.124
limb morphogenesisGO:00351081490.124
immune effector processGO:00022523210.123
Fly
positive regulation of transferase activityGO:00513471670.122
organic anion transportGO:00157111370.121
synapse organizationGO:00508081250.120
establishment or maintenance of cell polarityGO:0007163860.120
hair follicle developmentGO:0001942850.119
ubiquitin dependent protein catabolic processGO:00065111290.119
neural tube formationGO:00018411080.119
regulation of cell sizeGO:0008361720.119
male gamete generationGO:00482322850.118
cell divisionGO:00513011200.118
synaptic vesicle transportGO:0048489570.117
eye photoreceptor cell developmentGO:0042462310.115
cytokine biosynthetic processGO:0042089680.114
Mouse
negative regulation of cell cycleGO:00457861230.114
mitotic cell cycleGO:00002781950.112
positive regulation of osteoclast differentiationGO:0045672150.110
extrinsic apoptotic signaling pathwayGO:00971911260.110
forebrain developmentGO:00309003020.110
programmed necrotic cell deathGO:0097300280.106
reactive oxygen species metabolic processGO:0072593840.106
protein localization to organelleGO:00333651850.105
calcium ion homeostasisGO:00550741270.105
nucleobase containing small molecule metabolic processGO:00550863520.104
positive regulation of interferon alpha productionGO:003272740.103
regulation of transporter activityGO:0032409570.103
Mouse
positive regulation of cell migrationGO:00303351090.102
amine metabolic processGO:0009308450.102
metal ion homeostasisGO:00550651890.097
negative regulation of cellular amino acid metabolic processGO:004576300.097
positive regulation of growthGO:00459271040.097
nucleoside triphosphate metabolic processGO:00091412300.097
negative regulation of protein metabolic processGO:00512482820.093
epidermis developmentGO:00085441870.093
regulation of protein complex assemblyGO:0043254830.092
t cell activationGO:00421102890.092
regulation of secretionGO:00510462740.090
organelle assemblyGO:00709251770.089
germ cell developmentGO:00072811850.089
tube formationGO:00351481400.089
axon guidanceGO:00074111410.088
spermatogenesisGO:00072832840.088
positive regulation of type i interferon productionGO:0032481140.088
Mouse
purine nucleoside metabolic processGO:00422782410.087
cation homeostasisGO:00550802120.087
positive regulation of rac protein signal transductionGO:003502210.086
cellular amino acid metabolic processGO:00065201030.086
histone acetylationGO:0016573410.085
heterocycle catabolic processGO:00467002800.085
neural tube closureGO:0001843900.085
cation transportGO:00068123990.085
Mouse
establishment of organelle localizationGO:00516561220.084
synapse assemblyGO:0007416560.084
activation of mapkk activityGO:0000186150.083
regulation of fat cell differentiationGO:0045598810.083
cell substrate adhesionGO:00315891300.083
establishment or maintenance of apical basal cell polarityGO:0035088210.082
cell fate determinationGO:0001709320.082
immune response activating signal transductionGO:00027571160.082
regulation of secretion by cellGO:19035302490.081
leukocyte homeostasisGO:0001776790.081
Mouse
regulation of transferase activityGO:00513382630.081
cellular response to dna damage stimulusGO:00069742070.081
platelet derived growth factor receptor alpha signaling pathwayGO:003579030.080
gliogenesisGO:00420631410.080
antibacterial peptide biosynthetic processGO:000278020.080
Fly
regulation of epithelial cell proliferationGO:00506781410.079
response to organic cyclic compoundGO:00140701980.078
intracellular cholesterol transportGO:003236730.078
cellular amide metabolic processGO:0043603580.077
Fly
oocyte axis specificationGO:000730920.077
epithelial cell developmentGO:00020641590.077
negative regulation of cell cycle phase transitionGO:1901988480.077
microtubule based processGO:00070172360.077
purine ribonucleoside catabolic processGO:00461302050.077
establishment of protein localization to organelleGO:00725941180.076
response to growth factorGO:00708481980.076
modification dependent protein catabolic processGO:00199411330.076
autophagyGO:0006914450.076
posttranscriptional regulation of gene expressionGO:00106081550.075
peptidyl tyrosine phosphorylationGO:00181081430.075
defense response to gram positive bacteriumGO:0050830500.075
Mouse
limb developmentGO:00601731660.075
positive regulation of hydrolase activityGO:00513451480.074
regulation of ion transportGO:00432692150.074
Mouse
lung alveolus developmentGO:0048286450.074
cellular response to extracellular stimulusGO:0031668810.074
regulation of map kinase activityGO:00434051200.073
regulation of type i interferon productionGO:0032479220.073
Mouse
cellular chemical homeostasisGO:00550822150.072
single organismal cell cell adhesionGO:00163371310.072
antimicrobial peptide biosynthetic processGO:000277720.072
Fly
regulation of neuron deathGO:19012141340.072
positive regulation of cell cycleGO:0045787920.072
hair cycleGO:0042633900.072
regulation of autophagyGO:0010506300.071
multicellular organismal homeostasisGO:00488711640.071
response to metal ionGO:0010038470.070
negative regulation of response to endoplasmic reticulum stressGO:190357380.070
regulation of transmembrane transportGO:00347621280.069
Mouse
female gamete generationGO:0007292740.069
innate immune responseGO:00450871570.068
Mouse Fly
regulation of ion transmembrane transporter activityGO:0032412540.068
Mouse
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.068
negative regulation of phosphate metabolic processGO:00459361840.067
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.067
morphogenesis of a branching epitheliumGO:00611381930.066
regulation of keratinocyte differentiationGO:0045616110.066
myeloid leukocyte activationGO:0002274830.066
endomembrane system organizationGO:00102561470.065
regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014810.065
molting cycleGO:0042303900.065
exocytosisGO:00068871210.065
cell type specific apoptotic processGO:00972852680.064
leukocyte proliferationGO:00706611720.064
Mouse
endodermal cell fate specificationGO:000171440.064
transmission of nerve impulseGO:0019226760.064
muscle cell developmentGO:00550011330.063
regulation of ossificationGO:00302781120.063
cellular response to cytokine stimulusGO:00713451890.062
Human
ribose phosphate metabolic processGO:00196932910.062
regulation of cellular catabolic processGO:00313292420.062
positive regulation of protein kinase activityGO:00458601440.062
positive regulation of cell deathGO:00109422240.061
tube closureGO:0060606910.061
response to extracellular stimulusGO:00099911270.061
regulation of endodermal cell fate specificationGO:004266320.061
oocyte anterior posterior axis specificationGO:000731420.060
embryonic digit morphogenesisGO:0042733560.060
response to inorganic substanceGO:0010035960.060
foregut regionalizationGO:006042330.060
regulation of myeloid leukocyte differentiationGO:0002761580.060
muscle tissue developmentGO:00605373080.059
negative regulation of cellular response to growth factor stimulusGO:0090288460.059
regulation of proteolysisGO:00301621640.059
central nervous system neuron differentiationGO:00219531620.059
positive regulation of ossificationGO:0045778470.059
stem cell proliferationGO:00720891170.059
embryonic hemopoiesisGO:0035162230.058
negative regulation of kinase activityGO:0033673810.058
response to sterolGO:003631440.057
organelle fissionGO:00482851700.057
regulation of neuron apoptotic processGO:00435231220.057
neurotransmitter transportGO:0006836760.057
multicellular organism growthGO:00352641610.056
ribonucleoside metabolic processGO:00091192450.056
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.056
neural tube developmentGO:00219151600.056
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.056
endodermal cell fate commitmentGO:0001711120.055
regulation of mitotic cell cycle phase transitionGO:1901990730.055
keratinocyte differentiationGO:0030216480.055
camera type eye photoreceptor cell differentiationGO:0060219150.054
cell maturationGO:00484691270.054
ribonucleoside monophosphate metabolic processGO:0009161800.054
regulation of ripoptosome assembly involved in necroptotic processGO:190244230.054
negative regulation of cell motilityGO:2000146610.054
attachment of spindle microtubules to kinetochoreGO:000860840.053
small molecule catabolic processGO:0044282710.053
regulation of system processGO:00440572000.053
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.052
compound eye developmentGO:004874910.052
regulation of peptidyl tyrosine phosphorylationGO:0050730930.052
regulation of cellular response to growth factor stimulusGO:0090287820.052
digestive system developmentGO:00551232000.052
Zebrafish
regulation of neuronal synaptic plasticityGO:0048168300.052
purine nucleoside triphosphate catabolic processGO:00091462030.051
oxidation reduction processGO:00551143420.051
canonical wnt signaling pathwayGO:00600701300.051
hemostasisGO:0007599780.051
positive regulation of cell developmentGO:00107202370.051
oocyte differentiationGO:0009994350.050
nucleobase containing compound transportGO:0015931270.050
positive regulation of myeloid leukocyte differentiationGO:0002763260.050
negative regulation of phosphorylationGO:00423261660.050
purine ribonucleoside monophosphate metabolic processGO:0009167800.049
g protein coupled receptor signaling pathwayGO:00071862430.049
regulation of camp biosynthetic processGO:0030817250.049
positive regulation of programmed cell deathGO:00430682180.048
activation of jnkk activityGO:000725630.048
response to acid chemicalGO:00011011110.048
cellular protein complex assemblyGO:00436231160.048
purine nucleotide catabolic processGO:00061952110.048
cardiac chamber developmentGO:00032051080.048
response to fatty acidGO:007054280.048
lipid storageGO:0019915360.047
nucleotide metabolic processGO:00091173320.047
peptidyl lysine modificationGO:0018205770.047
regulation of cell migrationGO:00303342190.047
cellular divalent inorganic cation homeostasisGO:00725031270.047
regulation of epithelial cell migrationGO:0010632350.047
photoreceptor cell differentiationGO:0046530520.047
positive regulation of transporter activityGO:0032411170.046
Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.046
establishment of synaptic vesicle localizationGO:0097480570.046
negative regulation of lymphocyte activationGO:0051250910.046
chondrocyte differentiationGO:0002062720.046
proteasomal protein catabolic processGO:0010498980.046
regulation of purine nucleotide metabolic processGO:19005421690.046
internal protein amino acid acetylationGO:0006475420.046
heparan sulfate proteoglycan metabolic processGO:0030201100.046
peptidyl serine phosphorylationGO:0018105740.045
Fly
segmentationGO:0035282930.045
Zebrafish
oogenesisGO:0048477560.045
keratinocyte proliferationGO:0043616210.045
cellular transition metal ion homeostasisGO:0046916320.045
regulation of antimicrobial peptide productionGO:000278410.044
Fly
organophosphate biosynthetic processGO:00904071220.044
mitochondrial transportGO:0006839360.044
dna templated transcription initiationGO:0006352130.044
regulation of ras gtpase activityGO:0032318880.044
regulation of mapk cascadeGO:00434082480.044
spermatid differentiationGO:00485151150.044
nucleotide biosynthetic processGO:0009165780.044
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.044
regulation of cellular protein catabolic processGO:1903362610.043
regulation of protein secretionGO:0050708820.043
ribonucleoside triphosphate metabolic processGO:00091992200.042
pattern recognition receptor signaling pathwayGO:0002221470.042
regulation of canonical wnt signaling pathwayGO:0060828820.042
regulation of protein catabolic processGO:00421761080.042
regulation of epidermis developmentGO:0045682330.042
embryonic placenta developmentGO:0001892980.042
multicellular organismal signalingGO:0035637910.041
renal system developmentGO:00720012250.041
humoral immune responseGO:0006959570.041
Fly
cellular ion homeostasisGO:00068731650.041
urogenital system developmentGO:00016552610.041
intracellular lipid transportGO:003236530.040
response to radiationGO:00093141650.040
positive regulation of nervous system developmentGO:00519622210.040
eye photoreceptor cell differentiationGO:0001754410.040
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.040
regulation of protein transportGO:00512231630.040
regulation of endocytosisGO:0030100690.040
regulation of nucleocytoplasmic transportGO:0046822730.040
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.039
innate immune response activating signal transductionGO:0002758500.039
columnar cuboidal epithelial cell differentiationGO:0002065820.039
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.039
lymphocyte proliferationGO:00466511640.038
Mouse
regulation of cytoskeleton organizationGO:00514931220.038
jak stat cascadeGO:0007259420.038
pallium developmentGO:00215431200.038
cardiac muscle tissue developmentGO:00487381300.037
digestive tract developmentGO:00485651900.037
Zebrafish
response to organonitrogen compoundGO:00102432460.037
asymmetric cell divisionGO:000835680.037
lymphocyte activation involved in immune responseGO:0002285930.037
mesenchyme developmentGO:00604851520.037
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.037
regulation of hydrolase activityGO:00513362460.037
formation of radial glial scaffoldsGO:002194340.037
anion transportGO:00068201770.037
morphogenesis of a polarized epitheliumGO:0001738370.037
nucleoside monophosphate catabolic processGO:0009125590.037
somatic stem cell maintenanceGO:0035019470.037
divalent inorganic cation homeostasisGO:00725071380.037
response to tumor necrosis factorGO:0034612260.036
Human
positive regulation of leukocyte differentiationGO:1902107860.036
intracellular sterol transportGO:003236630.036
purine nucleoside monophosphate catabolic processGO:0009128580.036
purine ribonucleoside triphosphate catabolic processGO:00092071990.036
asymmetric stem cell divisionGO:009872230.036
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.036
mapk cascadeGO:00001652810.035
positive regulation of peptidase activityGO:0010952490.035
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.035
establishment of tissue polarityGO:0007164280.035
receptor mediated endocytosisGO:0006898510.035
tissue homeostasisGO:00018941150.035
positive regulation of protein localization to nucleusGO:1900182300.035
negative regulation of epidermal growth factor activated receptor activityGO:000717530.034
ribonucleoside catabolic processGO:00424542060.034
organic hydroxy compound metabolic processGO:19016152030.034
germ line stem cell divisionGO:004207820.034
oocyte constructionGO:000730820.034
multi multicellular organism processGO:00447061090.034
regulation of neurotransmitter secretionGO:0046928290.033
visual perceptionGO:0007601520.033
regulation of neurotransmitter transportGO:0051588350.033
peptidyl lysine acetylationGO:0018394450.033
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.033
establishment or maintenance of bipolar cell polarityGO:0061245210.033

Chuk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.397
cancerDOID:16200.155
organ system cancerDOID:005068600.155
disease of anatomical entityDOID:700.100
integumentary system diseaseDOID:1600.100
large intestine cancerDOID:567200.079
colon cancerDOID:21900.079
gastrointestinal system cancerDOID:311900.079
intestinal cancerDOID:1015500.079
colorectal cancerDOID:925600.079
disease of metabolismDOID:001466700.069
urinary system cancerDOID:399600.069
skin diseaseDOID:3700.066
inherited metabolic disorderDOID:65500.041