Mus musculus

0 known processes

Iars2

isoleucine-tRNA synthetase 2, mitochondrial

(Aliases: MGC63429,2010002H18Rik,C79125)

Iars2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
coenzyme metabolic processGO:0006732520.181
oxidation reduction processGO:00551143420.180
cellular lipid metabolic processGO:00442553230.150
coenzyme biosynthetic processGO:0009108230.141
nucleobase containing small molecule metabolic processGO:00550863520.111
cellular ketone metabolic processGO:0042180840.110
sulfur compound metabolic processGO:00067901000.106
fatty acid metabolic processGO:00066311210.104
monocarboxylic acid metabolic processGO:00327871910.102
aromatic compound catabolic processGO:00194392860.098
purine nucleotide metabolic processGO:00061633020.096
purine ribonucleotide metabolic processGO:00091502900.093
heterocycle catabolic processGO:00467002800.089
purine nucleoside metabolic processGO:00422782410.077
purine containing compound metabolic processGO:00725213110.071
glycosyl compound metabolic processGO:19016572460.068
purine nucleoside triphosphate metabolic processGO:00091442260.064
mitochondrion organizationGO:00070051340.063
nucleoside phosphate metabolic processGO:00067533380.059
cellular nitrogen compound catabolic processGO:00442702800.059
intracellular protein transportGO:00068862040.058
nucleotide metabolic processGO:00091173320.058
ribonucleotide metabolic processGO:00092592910.058
nucleoside metabolic processGO:00091162460.057
regulation of cellular ketone metabolic processGO:0010565660.056
nucleoside triphosphate metabolic processGO:00091412300.055
acetyl coa biosynthetic process from pyruvateGO:000608630.055
organic cyclic compound catabolic processGO:19013612950.055
acyl coa metabolic processGO:0006637190.054
thioester metabolic processGO:0035383190.053
cellular amino acid metabolic processGO:00065201030.053
apoptotic signaling pathwayGO:00971903060.053
ribose phosphate metabolic processGO:00196932910.053
membrane organizationGO:00610242450.052
purine ribonucleoside metabolic processGO:00461282410.047
ribonucleoside triphosphate metabolic processGO:00091992200.046
action potentialGO:0001508780.042
cofactor metabolic processGO:0051186800.040
ribonucleoside metabolic processGO:00091192450.040
carbohydrate derivative catabolic processGO:19011362310.039
cellular amine metabolic processGO:0044106440.039
intrinsic apoptotic signaling pathwayGO:00971931320.039
regulation of cellular amino acid metabolic processGO:000652150.039
transmission of nerve impulseGO:0019226760.038
fatty acid oxidationGO:0019395280.037
energy derivation by oxidation of organic compoundsGO:0015980770.036
organonitrogen compound catabolic processGO:19015652640.036
amine metabolic processGO:0009308450.036
regulation of cellular catabolic processGO:00313292420.036
regulation of cellular amine metabolic processGO:0033238200.035
response to oxidative stressGO:00069791230.034
purine ribonucleoside triphosphate metabolic processGO:00092052200.034
organophosphate catabolic processGO:00464342320.034
acetyl coa biosynthetic processGO:000608550.033
lipid biosynthetic processGO:00086101790.033
regulation of hydrolase activityGO:00513362460.033
purine nucleotide catabolic processGO:00061952110.032
organic acid catabolic processGO:0016054510.031
small molecule biosynthetic processGO:00442831320.031
thioester biosynthetic processGO:003538470.031
cofactor biosynthetic processGO:0051188410.031
positive regulation of cellular amine metabolic processGO:003324050.029
cellular macromolecule catabolic processGO:00442652060.028
acyl coa biosynthetic processGO:007161670.028
multicellular organismal signalingGO:0035637910.028
nucleotide catabolic processGO:00091662170.028
positive regulation of cellular amino acid metabolic processGO:004576430.027
macromolecule catabolic processGO:00090572810.027
response to organonitrogen compoundGO:00102432460.027
ribonucleotide catabolic processGO:00092612080.027
epithelial tube morphogenesisGO:00605623030.027
neuronal action potentialGO:0019228540.027
positive regulation of protein modification processGO:00314012990.026
regulation of membrane potentialGO:00423911920.026
positive regulation of protein phosphorylationGO:00019342420.025
anatomical structure homeostasisGO:00602491450.025
lipid oxidationGO:0034440290.025
cell type specific apoptotic processGO:00972852680.025
alcohol metabolic processGO:00060661160.025
translationGO:0006412930.024
nucleoside catabolic processGO:00091642060.024
purine nucleoside triphosphate catabolic processGO:00091462030.024
ras protein signal transductionGO:0007265770.024
purine ribonucleotide catabolic processGO:00091542080.023
nucleoside phosphate catabolic processGO:19012922220.023
regulation of purine nucleotide metabolic processGO:19005421690.023
ribonucleoside triphosphate catabolic processGO:00092031990.023
generation of precursor metabolites and energyGO:00060911030.022
cellular lipid catabolic processGO:0044242520.022
glycosyl compound catabolic processGO:19016582060.022
maintenance of locationGO:0051235890.022
purine nucleoside catabolic processGO:00061522050.022
negative regulation of phosphorus metabolic processGO:00105631840.022
mitochondrial translationGO:003254340.022
dna metabolic processGO:00062593030.022
nucleoside triphosphate catabolic processGO:00091432050.021
lipid localizationGO:00108761260.021
organelle localizationGO:00516401790.021
homeostasis of number of cellsGO:00488722100.021
regulation of nucleotide metabolic processGO:00061401690.021
purine containing compound catabolic processGO:00725232130.021
small gtpase mediated signal transductionGO:0007264970.021
lipid modificationGO:0030258650.021
morphogenesis of embryonic epitheliumGO:00163311590.021
regulation of secretion by cellGO:19035302490.021
protein processingGO:00164851630.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
nucleoside monophosphate metabolic processGO:0009123850.020
cytokine productionGO:00018163190.020
ribonucleoside catabolic processGO:00424542060.020
small molecule catabolic processGO:0044282710.020
phospholipid metabolic processGO:0006644870.019
regulation of protein localizationGO:00328802310.019
regulation of organelle organizationGO:00330432890.019
nuclear transportGO:00511691390.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
purine ribonucleoside catabolic processGO:00461302050.019
guanosine containing compound metabolic processGO:19010681440.019
protein localization to organelleGO:00333651850.019
negative regulation of phosphate metabolic processGO:00459361840.018
ensheathment of neuronsGO:0007272760.018
monocarboxylic acid catabolic processGO:0072329270.018
regulation of apoptotic signaling pathwayGO:20012331970.018
carboxylic acid catabolic processGO:0046395510.018
cellular response to growth factor stimulusGO:00713631970.018
regulation of cell activationGO:00508652890.018
atp metabolic processGO:0046034750.017
organonitrogen compound biosynthetic processGO:19015661920.017
gtp metabolic processGO:00460391440.017
regulation of establishment of protein localizationGO:00702011810.017
organic hydroxy compound metabolic processGO:19016152030.017
transmembrane transportGO:00550854120.017
negative regulation of apoptotic signaling pathwayGO:20012341040.017
sulfur compound biosynthetic processGO:0044272370.017
ion transmembrane transportGO:00342203610.017
neural tube formationGO:00018411080.017
carbohydrate metabolic processGO:00059752300.017
synapse organizationGO:00508081250.016
gtp catabolic processGO:00061841430.016
lipid catabolic processGO:0016042690.016
cytoplasmic transportGO:00164822340.016
positive regulation of cell activationGO:00508671580.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
positive regulation of organelle organizationGO:00106381280.016
rho protein signal transductionGO:0007266320.016
forebrain developmentGO:00309003020.016
regulation of kinase activityGO:00435492490.016
immune effector processGO:00022523210.016
blood circulationGO:00080151950.016
nucleocytoplasmic transportGO:00069131390.016
regulation of leukocyte differentiationGO:19021051590.016
glycerol ether metabolic processGO:000666220.016
negative regulation of immune system processGO:00026832090.016
response to organic cyclic compoundGO:00140701980.015
regulation of protein transportGO:00512231630.015
negative regulation of cellular amine metabolic processGO:003323910.015
regulation of cytokine productionGO:00018172660.015
multicellular organismal homeostasisGO:00488711640.015
positive regulation of hydrolase activityGO:00513451480.015
ribonucleoside monophosphate metabolic processGO:0009161800.015
myelinationGO:0042552740.015
carbohydrate derivative biosynthetic processGO:19011371830.015
tube formationGO:00351481400.015
glycerophospholipid metabolic processGO:0006650710.015
interleukin 8 productionGO:003263740.014
regulation of mitochondrion organizationGO:0010821270.014
cellular respirationGO:0045333380.014
cation transmembrane transportGO:00986552660.014
guanosine containing compound catabolic processGO:19010691440.014
protein maturationGO:00516041760.014
regulation of interleukin 8 productionGO:003267730.014
endomembrane system organizationGO:00102561470.014
leukocyte differentiationGO:00025213420.014
protein targetingGO:00066051430.014
protein oligomerizationGO:0051259670.014
lateral inhibitionGO:004633110.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
regulation of secretionGO:00510462740.014
protein secretionGO:00093061110.014
response to growth factorGO:00708481980.014
embryonic epithelial tube formationGO:00018381300.014
axon ensheathmentGO:0008366760.014
cellular carbohydrate metabolic processGO:00442621190.014
mitotic cell cycleGO:00002781950.014
cation transportGO:00068123990.014
fatty acid catabolic processGO:0009062250.014
ossificationGO:00015032160.014
protein localization to nucleusGO:00345041210.013
hematopoietic progenitor cell differentiationGO:00022441430.013
cellular response to dna damage stimulusGO:00069742070.013
multicellular organism growthGO:00352641610.013
negative regulation of protein metabolic processGO:00512482820.013
adult behaviorGO:00305341350.013
negative regulation of molecular functionGO:00440922580.013
cristae formationGO:004240730.013
engulfment of apoptotic cellGO:004365230.013
mitochondrion transport along microtubuleGO:004749730.013
organophosphate biosynthetic processGO:00904071220.013
peptidyl amino acid modificationGO:00181933360.013
posttranscriptional regulation of gene expressionGO:00106081550.013
cell adhesionGO:00071553290.013
protein importGO:00170381010.013
peptidyl serine modificationGO:0018209830.013
mitochondrion morphogenesisGO:0070584130.013
negative regulation of intracellular signal transductionGO:19025321670.013
response to endoplasmic reticulum stressGO:0034976530.013
regulation of cell migrationGO:00303342190.013
cellular response to organonitrogen compoundGO:00714171450.013
negative regulation of dna replicationGO:000815640.013
cellular response to hormone stimulusGO:00328701500.013
negative regulation of cellular protein metabolic processGO:00322692470.013
negative regulation of cellular component organizationGO:00511291940.013
protein localization to membraneGO:00726571080.013
response to molecule of bacterial originGO:00022371430.013
neutral lipid metabolic processGO:0006638570.012
g protein coupled receptor signaling pathwayGO:00071862430.012
digestive tract developmentGO:00485651900.012
urogenital system developmentGO:00016552610.012
cellular amide metabolic processGO:0043603580.012
tube closureGO:0060606910.012
cofactor transportGO:005118140.012
fatty acid beta oxidationGO:0006635160.012
regulation of nucleotide catabolic processGO:00308111220.012
cellular homeostasisGO:00197252400.012
regulation of myeloid cell differentiationGO:0045637960.012
camera type eye developmentGO:00430102660.012
microtubule based processGO:00070172360.012
regulation of mitotic cell cycle phase transitionGO:1901990730.012
mitochondrial fusionGO:000805390.012
carbohydrate biosynthetic processGO:0016051740.012
positive regulation of growthGO:00459271040.012
purine nucleotide biosynthetic processGO:0006164650.012
regulation of lymphocyte activationGO:00512492400.012
regulation of lipid metabolic processGO:00192161180.012
anion transportGO:00068201770.012
neuron apoptotic processGO:00514021420.012
renal system developmentGO:00720012250.011
response to peptide hormoneGO:00434341270.011
inorganic cation transmembrane transportGO:00986622070.011
cellular response to oxidative stressGO:0034599760.011
macromolecule methylationGO:00434141200.011
gland developmentGO:00487323300.011
regulation of ion transportGO:00432692150.011
neural tube developmentGO:00219151600.011
t cell apoptotic processGO:0070231390.011
spermatogenesisGO:00072832840.011
methylationGO:00322591340.011
ribose phosphate biosynthetic processGO:0046390590.011
nitrogen compound transportGO:00717052710.011
circulatory system processGO:00030131970.011
response to insulinGO:00328681000.011
regulation of cell motilityGO:20001452360.011
apoptotic mitochondrial changesGO:0008637480.011
tissue homeostasisGO:00018941150.011
regulation of homeostatic processGO:00328441820.011
endocytosisGO:00068971680.011
stem cell differentiationGO:00488632680.011
positive regulation of protein kinase activityGO:00458601440.011
monosaccharide metabolic processGO:00059961060.011
epithelial tube formationGO:00721751300.011
digestive system developmentGO:00551232000.011
epithelial cell proliferationGO:00506731740.011
regulation of cell cycleGO:00517262810.011
positive regulation of cell developmentGO:00107202370.011
negative regulation of granulocyte differentiationGO:003085330.010
membrane fusionGO:0061025380.010
cellular response to peptideGO:1901653920.010
neuron migrationGO:00017641220.010
purine ribonucleotide biosynthetic processGO:0009152590.010
regulation of defense responseGO:00313472330.010
regulation of transferase activityGO:00513382630.010
establishment of protein localization to organelleGO:00725941180.010
innate immune responseGO:00450871570.010
positive regulation of lymphocyte activationGO:00512511400.010
cation homeostasisGO:00550802120.010
positive regulation of cellular catabolic processGO:00313311480.010
defense response to other organismGO:00985421970.010
regulation of ion transmembrane transportGO:00347651190.010
regulation of purine nucleotide catabolic processGO:00331211220.010
regulation of cytoplasmic transportGO:19036491120.010
dna integrity checkpointGO:0031570280.010
peptidyl serine phosphorylationGO:0018105740.010
telencephalon developmentGO:00215371860.010
regulation of protein secretionGO:0050708820.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
neuron deathGO:00709971540.010
positive regulation of kinase activityGO:00336741550.010

Iars2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.045
inherited metabolic disorderDOID:65500.031
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
musculoskeletal system diseaseDOID:1700.013
amino acid metabolic disorderDOID:925200.011
carbohydrate metabolic disorderDOID:297800.010
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010
sensory system diseaseDOID:005015500.010