Mus musculus

86 known processes

Lias

lipoic acid synthetase

(Aliases: C77512,mLip1,4933425M12Rik,2900022L22Rik,MGC7254,7a5ex)

Lias biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrion organizationGO:00070051340.183
energy derivation by oxidation of organic compoundsGO:0015980770.117
sulfur compound biosynthetic processGO:0044272370.105
purine ribonucleoside metabolic processGO:00461282410.103
nucleobase containing small molecule metabolic processGO:00550863520.089
protein catabolic processGO:00301632210.083
protein processingGO:00164851630.072
purine ribonucleotide metabolic processGO:00091502900.065
regulation of membrane potentialGO:00423911920.062
cellular ketone metabolic processGO:0042180840.059
regulation of cellular catabolic processGO:00313292420.057
acetyl coa biosynthetic process from pyruvateGO:000608630.055
coenzyme biosynthetic processGO:0009108230.051
protein processing involved in protein targeting to mitochondrionGO:000662710.051
proteasomal protein catabolic processGO:0010498980.049
endocytosisGO:00068971680.049
purine nucleoside metabolic processGO:00422782410.047
cellular amino acid metabolic processGO:00065201030.047
protein maturationGO:00516041760.046
purine nucleoside monophosphate metabolic processGO:0009126810.046
cellular macromolecule catabolic processGO:00442652060.044
regulation of cellular amine metabolic processGO:0033238200.040
regulation of cellular ketone metabolic processGO:0010565660.039
sulfur compound metabolic processGO:00067901000.038
macromolecule catabolic processGO:00090572810.038
nucleotide metabolic processGO:00091173320.036
nucleoside phosphate metabolic processGO:00067533380.036
purine ribonucleoside triphosphate metabolic processGO:00092052200.035
apoptotic mitochondrial changesGO:0008637480.034
proteolysis involved in cellular protein catabolic processGO:00516031470.034
cellular protein catabolic processGO:00442571550.034
intrinsic apoptotic signaling pathwayGO:00971931320.033
nucleoside monophosphate metabolic processGO:0009123850.032
acetyl coa biosynthetic processGO:000608550.032
negative regulation of protein metabolic processGO:00512482820.032
aromatic compound catabolic processGO:00194392860.031
cofactor metabolic processGO:0051186800.031
cellular amine metabolic processGO:0044106440.029
regulation of cellular amino acid metabolic processGO:000652150.029
negative regulation of intracellular signal transductionGO:19025321670.028
regulation of protein catabolic processGO:00421761080.028
transmembrane transportGO:00550854120.028
ribonucleoside metabolic processGO:00091192450.027
neuronal action potentialGO:0019228540.027
negative regulation of protein maturationGO:1903318790.027
regulation of endopeptidase activityGO:0052548890.026
modification dependent macromolecule catabolic processGO:00436321330.026
ion transmembrane transportGO:00342203610.026
mitochondrion degradationGO:000042230.026
positive regulation of proteolysisGO:0045862850.026
negative regulation of apoptotic signaling pathwayGO:20012341040.026
cellular response to dna damage stimulusGO:00069742070.026
atp metabolic processGO:0046034750.026
nucleoside metabolic processGO:00091162460.025
ribose phosphate metabolic processGO:00196932910.025
nucleoside triphosphate metabolic processGO:00091412300.024
acyl coa biosynthetic processGO:007161670.024
ribonucleoside monophosphate metabolic processGO:0009161800.024
regulation of proteolysisGO:00301621640.023
translationGO:0006412930.023
protein localization to organelleGO:00333651850.022
cristae formationGO:004240730.022
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.022
positive regulation of apoptotic processGO:00430652170.022
positive regulation of cellular amine metabolic processGO:003324050.021
purine nucleotide metabolic processGO:00061633020.021
purine ribonucleoside monophosphate metabolic processGO:0009167800.021
ribonucleoside triphosphate metabolic processGO:00091992200.021
cell type specific apoptotic processGO:00972852680.021
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.021
carbohydrate derivative catabolic processGO:19011362310.021
modification dependent protein catabolic processGO:00199411330.020
locomotory behaviorGO:00076261950.020
dephosphorylationGO:00163111290.020
negative regulation of proteolysisGO:0045861740.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
membrane organizationGO:00610242450.020
positive regulation of protein catabolic processGO:0045732600.019
purine containing compound metabolic processGO:00725213110.019
regulation of hydrolase activityGO:00513362460.019
chromatin organizationGO:00063252060.019
mitochondrial electron transport nadh to ubiquinoneGO:000612040.019
regulation of epithelial cell proliferationGO:00506781410.019
regulation of protein maturationGO:1903317960.019
cofactor biosynthetic processGO:0051188410.019
negative regulation of cell proliferationGO:00082852960.018
heterocycle catabolic processGO:00467002800.018
negative regulation of cellular protein metabolic processGO:00322692470.018
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.018
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.017
organic cyclic compound catabolic processGO:19013612950.017
purine nucleotide catabolic processGO:00061952110.017
action potentialGO:0001508780.017
purine nucleoside triphosphate catabolic processGO:00091462030.016
oxidation reduction processGO:00551143420.016
exocytosisGO:00068871210.016
regulation of secretion by cellGO:19035302490.016
posttranscriptional regulation of gene expressionGO:00106081550.016
neural tube formationGO:00018411080.016
lateral inhibitionGO:004633110.016
positive regulation of cellular protein catabolic processGO:1903364340.016
male gamete generationGO:00482322850.015
regulation of proteasomal protein catabolic processGO:0061136460.015
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.015
neuron apoptotic processGO:00514021420.015
organophosphate catabolic processGO:00464342320.015
amine metabolic processGO:0009308450.015
cation transportGO:00068123990.015
ribonucleotide catabolic processGO:00092612080.015
circulatory system processGO:00030131970.015
negative regulation of cellular component organizationGO:00511291940.015
transmission of nerve impulseGO:0019226760.015
negative regulation of protein processingGO:0010955790.015
multicellular organism growthGO:00352641610.015
mitochondrial protein processingGO:003498250.015
ubiquitin dependent protein catabolic processGO:00065111290.015
positive regulation of cell deathGO:00109422240.014
regulation of organelle organizationGO:00330432890.014
phagocytosisGO:0006909660.014
pyruvate metabolic processGO:0006090280.014
spermatid differentiationGO:00485151150.014
spermatid developmentGO:00072861080.014
synapse organizationGO:00508081250.014
cation transmembrane transportGO:00986552660.014
apoptotic signaling pathwayGO:00971903060.014
positive regulation of hydrolase activityGO:00513451480.014
small molecule biosynthetic processGO:00442831320.014
response to organonitrogen compoundGO:00102432460.013
response to growth factorGO:00708481980.013
generation of precursor metabolites and energyGO:00060911030.013
multicellular organismal agingGO:0010259240.013
regulation of mitotic cell cycle phase transitionGO:1901990730.013
regulation of cell cycle processGO:00105641600.013
blood circulationGO:00080151950.013
synaptic transmissionGO:00072683290.013
nucleotide catabolic processGO:00091662170.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
regulation of cellular protein catabolic processGO:1903362610.013
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.013
cellular amide metabolic processGO:0043603580.013
regulation of mitochondrial fissionGO:009014030.013
positive regulation of protein modification processGO:00314012990.012
trna wobble uridine modificationGO:000209820.012
nucleoside monophosphate catabolic processGO:0009125590.012
trna metabolic processGO:0006399110.012
regulation of secretionGO:00510462740.012
negative regulation of cellular amine metabolic processGO:003323910.012
vascular process in circulatory systemGO:0003018620.012
organelle fusionGO:0048284280.012
glycosyl compound metabolic processGO:19016572460.012
cytoplasmic transportGO:00164822340.012
purine nucleoside triphosphate metabolic processGO:00091442260.011
nitrogen compound transportGO:00717052710.011
autophagyGO:0006914450.011
aldehyde catabolic processGO:004618540.011
protein modification by small protein conjugation or removalGO:00706472070.011
cardiac muscle tissue developmentGO:00487381300.011
negative regulation of epithelial cell proliferationGO:0050680640.011
germ cell developmentGO:00072811850.011
positive regulation of protein phosphorylationGO:00019342420.011
thioester metabolic processGO:0035383190.011
trna aminoacylationGO:004303910.011
purine ribonucleotide catabolic processGO:00091542080.011
cellular response to hormone stimulusGO:00328701500.011
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.011
positive regulation of cellular catabolic processGO:00313311480.011
mitotic cell cycleGO:00002781950.011
myelinationGO:0042552740.011
asymmetric stem cell divisionGO:009872230.010
neuron deathGO:00709971540.010
organic hydroxy compound transportGO:0015850930.010
nucleoside catabolic processGO:00091642060.010
regulation of reactive oxygen species metabolic processGO:2000377400.010
response to extracellular stimulusGO:00099911270.010
peptidyl amino acid modificationGO:00181933360.010
positive regulation of programmed cell deathGO:00430682180.010
cellular response to cytokine stimulusGO:00713451890.010
purine nucleoside monophosphate catabolic processGO:0009128580.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.010
cellular response to organonitrogen compoundGO:00714171450.010

Lias disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.036
disease of metabolismDOID:001466700.036
disease of anatomical entityDOID:700.023
nervous system diseaseDOID:86300.023
musculoskeletal system diseaseDOID:1700.015
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
physical disorderDOID:008001500.010