Mus musculus

58 known processes

Sirt3

sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)

(Aliases: 2310003L23Rik,AI848213,Sir2l3)

Sirt3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
coenzyme metabolic processGO:0006732520.553
acetate metabolic processGO:000608310.442
cellular amino acid metabolic processGO:00065201030.374
oxidation reduction processGO:00551143420.355
Human
monocarboxylic acid metabolic processGO:00327871910.254
coenzyme biosynthetic processGO:0009108230.206
cofactor metabolic processGO:0051186800.197
nucleobase containing small molecule metabolic processGO:00550863520.196
cellular aldehyde metabolic processGO:0006081120.187
small molecule biosynthetic processGO:00442831320.184
carboxylic acid biosynthetic processGO:0046394860.145
amine metabolic processGO:0009308450.123
cellular lipid metabolic processGO:00442553230.120
Mouse
cellular amine metabolic processGO:0044106440.112
ketone catabolic processGO:004218230.111
cellular amino acid biosynthetic processGO:0008652220.091
9 cis retinoic acid metabolic processGO:004290550.086
lipid biosynthetic processGO:00086101790.084
organonitrogen compound biosynthetic processGO:19015661920.083
regulation of cellular ketone metabolic processGO:0010565660.078
nadh metabolic processGO:000673410.076
organic acid biosynthetic processGO:0016053860.076
cellular ketone metabolic processGO:0042180840.074
sulfur compound biosynthetic processGO:0044272370.071
response to organonitrogen compoundGO:00102432460.070
Mouse
response to testosteroneGO:003357430.067
diterpenoid metabolic processGO:0016101240.067
renal system developmentGO:00720012250.064
energy derivation by oxidation of organic compoundsGO:0015980770.063
Human
regulation of cellular amino acid metabolic processGO:000652150.061
cellular modified amino acid metabolic processGO:0006575630.058
polyamine catabolic processGO:000659820.056
sulfur compound metabolic processGO:00067901000.053
iron sulfur cluster assemblyGO:001622630.052
cofactor biosynthetic processGO:0051188410.051
apoptotic signaling pathwayGO:00971903060.048
muscle tissue developmentGO:00605373080.047
striated muscle tissue developmentGO:00147062930.046
retinoid metabolic processGO:0001523240.046
regulation of response to drugGO:200102320.046
nucleoside phosphate metabolic processGO:00067533380.045
oxidoreduction coenzyme metabolic processGO:0006733160.045
glutathione metabolic processGO:0006749160.044
organic hydroxy compound metabolic processGO:19016152030.043
generation of precursor metabolites and energyGO:00060911030.042
Human
morphogenesis of embryonic epitheliumGO:00163311590.041
gland developmentGO:00487323300.039
nucleotide metabolic processGO:00091173320.037
embryonic organ morphogenesisGO:00485622760.036
positive regulation of cellular amine metabolic processGO:003324050.036
response to oxygen levelsGO:0070482620.036
small molecule catabolic processGO:0044282710.036
isoprenoid metabolic processGO:0006720290.036
camera type eye developmentGO:00430102660.035
fat cell differentiationGO:00454441600.034
Mouse
diterpenoid biosynthetic processGO:001610270.034
carbohydrate metabolic processGO:00059752300.034
sensory organ morphogenesisGO:00905962420.034
positive regulation of cellular amino acid metabolic processGO:004576430.033
regulation of hormone levelsGO:00108172110.032
Rat
cardiac muscle tissue developmentGO:00487381300.032
maintenance of locationGO:0051235890.031
Mouse
organonitrogen compound catabolic processGO:19015652640.031
developmental maturationGO:00217001930.031
Mouse
heart morphogenesisGO:00030071780.030
urogenital system developmentGO:00016552610.029
digestive tract developmentGO:00485651900.028
response to organic cyclic compoundGO:00140701980.028
Mouse
digestive system developmentGO:00551232000.028
regulation of cellular amine metabolic processGO:0033238200.028
nonribosomal peptide biosynthetic processGO:001918450.028
branched chain amino acid catabolic processGO:000908320.027
response to hyperoxiaGO:005509320.026
regulation of protein kinase activityGO:00458592320.026
response to molecule of bacterial originGO:00022371430.025
ethanol metabolic processGO:000606730.025
multicellular organismal homeostasisGO:00488711640.024
hormone metabolic processGO:0042445860.024
microtubule cytoskeleton organizationGO:00002261570.023
Mouse
terpenoid metabolic processGO:0006721250.023
rhythmic processGO:00485111740.023
alcohol metabolic processGO:00060661160.023
ribonucleoside metabolic processGO:00091192450.022
appendage developmentGO:00487361660.022
glycosyl compound metabolic processGO:19016572460.022
microtubule based processGO:00070172360.022
Mouse
regulation of organelle organizationGO:00330432890.022
Mouse
limb developmentGO:00601731660.022
regulation of membrane potentialGO:00423911920.022
Mouse
transmembrane transportGO:00550854120.021
liver developmentGO:0001889660.021
cellular response to acid chemicalGO:0071229680.021
monocarboxylic acid biosynthetic processGO:0072330610.021
peptide metabolic processGO:0006518460.021
ribonucleotide metabolic processGO:00092592910.021
response to lipopolysaccharideGO:00324961280.021
ear morphogenesisGO:00424711180.020
thioester metabolic processGO:0035383190.020
quinone metabolic processGO:190166170.020
nadph regenerationGO:000674020.020
pyruvate metabolic processGO:0006090280.020
hematopoietic progenitor cell differentiationGO:00022441430.019
development of primary female sexual characteristicsGO:0046545730.019
limb morphogenesisGO:00351081490.019
positive regulation of protein modification processGO:00314012990.019
purine ribonucleotide metabolic processGO:00091502900.019
forebrain developmentGO:00309003020.019
positive regulation of apoptotic processGO:00430652170.019
Mouse
regulation of epithelial cell proliferationGO:00506781410.019
negative regulation of cellular component organizationGO:00511291940.019
Mouse
hepaticobiliary system developmentGO:0061008670.018
response to extracellular stimulusGO:00099911270.018
Mouse
metallo sulfur cluster assemblyGO:003116330.018
macromolecule catabolic processGO:00090572810.018
Mouse
muscle cell differentiationGO:00426922610.018
positive regulation of protein phosphorylationGO:00019342420.018
myeloid leukocyte migrationGO:0097529570.017
response to growth factorGO:00708481980.017
response to nutrient levelsGO:00316671090.017
Mouse
kidney developmentGO:00018222130.017
primary alcohol metabolic processGO:0034308110.017
locomotory behaviorGO:00076261950.017
response to steroid hormoneGO:0048545560.017
ubiquitin dependent protein catabolic processGO:00065111290.017
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.017
proteolysis involved in cellular protein catabolic processGO:00516031470.017
Mouse
positive regulation of programmed cell deathGO:00430682180.017
Mouse
lung developmentGO:00303241640.017
response to acid chemicalGO:00011011110.017
ear developmentGO:00435832000.017
response to increased oxygen levelsGO:003629620.016
nicotinamide nucleotide metabolic processGO:0046496120.016
leukocyte migrationGO:00509001240.016
negative regulation of protein modification processGO:00314001630.016
neural nucleus developmentGO:0048857220.016
homeostasis of number of cellsGO:00488722100.016
cellular macromolecule catabolic processGO:00442652060.016
Mouse
protein localization to organelleGO:00333651850.016
nucleoside metabolic processGO:00091162460.016
tissue homeostasisGO:00018941150.016
pyridine nucleotide metabolic processGO:0019362120.016
positive regulation of cell deathGO:00109422240.016
Mouse
purine containing compound metabolic processGO:00725213110.015
retinoic acid metabolic processGO:0042573120.015
purine nucleotide metabolic processGO:00061633020.015
transmission of nerve impulseGO:0019226760.015
Mouse
nucleoside triphosphate metabolic processGO:00091412300.015
inner ear morphogenesisGO:00424721010.015
female sex differentiationGO:0046660840.015
substantia nigra developmentGO:002176220.015
epithelial cell proliferationGO:00506731740.015
neuromuscular processGO:0050905990.015
regulation of transferase activityGO:00513382630.015
cytokine productionGO:00018163190.015
nitrogen compound transportGO:00717052710.015
Rat
aldehyde catabolic processGO:004618540.015
skin developmentGO:00435882200.015
respiratory system developmentGO:00605411900.015
myeloid cell differentiationGO:00300992330.014
olfactory pit developmentGO:006016630.014
regionalizationGO:00030023370.014
embryonic appendage morphogenesisGO:00351131260.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
negative regulation of cellular protein metabolic processGO:00322692470.014
aromatic compound catabolic processGO:00194392860.014
steroid metabolic processGO:00082021190.014
9 cis retinoic acid biosynthetic processGO:004290450.014
regulation of cytokine productionGO:00018172660.014
cellular protein complex assemblyGO:00436231160.014
Mouse
terpenoid biosynthetic processGO:001611470.014
protein maturationGO:00516041760.013
neuromuscular process controlling balanceGO:0050885590.013
embryonic limb morphogenesisGO:00303261260.013
cellular response to lipidGO:00713961450.013
sensory perceptionGO:00076002450.013
retinoic acid biosynthetic processGO:000213870.013
asymmetric stem cell divisionGO:009872230.013
stem cell developmentGO:00488642190.013
mesenchyme developmentGO:00604851520.013
cellular response to hormone stimulusGO:00328701500.013
regulation of interleukin 8 productionGO:003267730.013
purine nucleoside metabolic processGO:00422782410.013
cellular amide metabolic processGO:0043603580.013
respiratory tube developmentGO:00303231670.013
neuronal action potentialGO:0019228540.013
Mouse
mapk cascadeGO:00001652810.013
Rat
stem cell differentiationGO:00488632680.013
asymmetric neuroblast divisionGO:005505910.012
cellular response to growth factor stimulusGO:00713631970.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
Mouse Rat
regulation of kinase activityGO:00435492490.012
cellular carbohydrate metabolic processGO:00442621190.012
reactive oxygen species metabolic processGO:0072593840.012
Mouse Rat
purine ribonucleoside metabolic processGO:00461282410.012
chemotaxisGO:00069352470.012
organic cyclic compound catabolic processGO:19013612950.012
cellular response to organonitrogen compoundGO:00714171450.012
Mouse
nucleoside phosphate catabolic processGO:19012922220.012
limbic system developmentGO:0021761720.012
cell type specific apoptotic processGO:00972852680.012
epithelial cell developmentGO:00020641590.012
nucleus accumbens developmentGO:002176810.012
anatomical structure homeostasisGO:00602491450.012
regulation of anatomical structure sizeGO:00900661780.012
multicellular organismal signalingGO:0035637910.012
Mouse
lateral inhibitionGO:004633110.012
striatum developmentGO:0021756140.012
bone developmentGO:00603481200.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
cellular modified amino acid biosynthetic processGO:0042398120.011
negative regulation of intracellular signal transductionGO:19025321670.011
Rat
pancreas developmentGO:0031016570.011
ribonucleoside catabolic processGO:00424542060.011
mitochondrion degradationGO:000042230.011
negative regulation of phosphorylationGO:00423261660.011
Mouse Rat
male gamete generationGO:00482322850.011
female gonad developmentGO:0008585710.011
response to light stimulusGO:00094161350.011
peptidyl amino acid modificationGO:00181933360.011
ensheathment of neuronsGO:0007272760.011
Mouse
nucleotide catabolic processGO:00091662170.011
negative regulation of phosphorus metabolic processGO:00105631840.011
Mouse Rat
lipid storageGO:0019915360.011
telencephalon developmentGO:00215371860.011
posttranscriptional regulation of gene expressionGO:00106081550.011
skeletal system developmentGO:00015013560.011
pyruvate transportGO:000684820.011
ovulation cycleGO:0042698590.011
action potentialGO:0001508780.011
Mouse
connective tissue developmentGO:00614481790.011
negative regulation of cell proliferationGO:00082852960.011
Mouse
circulatory system processGO:00030131970.010
response to retinoic acidGO:0032526560.010
negative regulation of phosphate metabolic processGO:00459361840.010
Mouse Rat
protein catabolic processGO:00301632210.010
Mouse
negative regulation of protein phosphorylationGO:00019331260.010
Mouse
cation transmembrane transportGO:00986552660.010
muscle system processGO:00030121410.010
glycosyl compound catabolic processGO:19016582060.010
proteasomal protein catabolic processGO:0010498980.010
Mouse
embryonic epithelial tube formationGO:00018381300.010
myeloid leukocyte differentiationGO:00025731190.010
anatomical structure maturationGO:0071695490.010
carbohydrate derivative biosynthetic processGO:19011371830.010
retinal metabolic processGO:004257450.010
response to alcoholGO:0097305480.010
neuron apoptotic processGO:00514021420.010
purine ribonucleotide catabolic processGO:00091542080.010
small gtpase mediated signal transductionGO:0007264970.010
purine nucleoside triphosphate metabolic processGO:00091442260.010
pyridine containing compound metabolic processGO:0072524140.010
intracellular receptor signaling pathwayGO:0030522740.010
nephron developmentGO:00720061090.010
carbohydrate derivative catabolic processGO:19011362310.010

Sirt3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.030
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.025
organ system cancerDOID:005068600.025
inherited metabolic disorderDOID:65500.018
nervous system diseaseDOID:86300.010
disease of anatomical entityDOID:700.010