Mus musculus

21 known processes

Sirt5

sirtuin 5 (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)

(Aliases: 1500032M05Rik,0610012J09Rik,AV001953)

Sirt5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180840.066
cellular amino acid metabolic processGO:00065201030.064
amine metabolic processGO:0009308450.058
regulation of cellular ketone metabolic processGO:0010565660.054
regulation of cellular amino acid metabolic processGO:000652150.049
regulation of cellular amine metabolic processGO:0033238200.047
cellular amine metabolic processGO:0044106440.047
oxidation reduction processGO:00551143420.046
coenzyme metabolic processGO:0006732520.043
lipid biosynthetic processGO:00086101790.043
nucleobase containing small molecule metabolic processGO:00550863520.043
nucleoside phosphate metabolic processGO:00067533380.039
cellular lipid metabolic processGO:00442553230.034
nucleotide metabolic processGO:00091173320.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
cellular nitrogen compound catabolic processGO:00442702800.031
response to organonitrogen compoundGO:00102432460.031
heterocycle catabolic processGO:00467002800.030
aromatic compound catabolic processGO:00194392860.029
glycosyl compound metabolic processGO:19016572460.029
ribonucleotide metabolic processGO:00092592910.027
purine nucleotide metabolic processGO:00061633020.026
regulation of organelle organizationGO:00330432890.026
positive regulation of cellular amine metabolic processGO:003324050.025
purine containing compound metabolic processGO:00725213110.025
nucleoside metabolic processGO:00091162460.025
apoptotic signaling pathwayGO:00971903060.024
transmembrane transportGO:00550854120.023
purine ribonucleotide metabolic processGO:00091502900.022
monocarboxylic acid metabolic processGO:00327871910.022
ribonucleoside metabolic processGO:00091192450.022
male gamete generationGO:00482322850.022
organic cyclic compound catabolic processGO:19013612950.022
organophosphate catabolic processGO:00464342320.022
dna metabolic processGO:00062593030.021
ribose phosphate metabolic processGO:00196932910.021
negative regulation of cellular amine metabolic processGO:003323910.021
nucleoside triphosphate metabolic processGO:00091412300.021
posttranscriptional regulation of gene expressionGO:00106081550.021
positive regulation of protein modification processGO:00314012990.021
purine nucleoside metabolic processGO:00422782410.020
organonitrogen compound catabolic processGO:19015652640.020
nitrogen compound transportGO:00717052710.020
purine ribonucleoside metabolic processGO:00461282410.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
negative regulation of cellular amino acid metabolic processGO:004576300.019
carbohydrate metabolic processGO:00059752300.019
purine nucleoside triphosphate metabolic processGO:00091442260.019
regulation of cell activationGO:00508652890.018
protein localization to organelleGO:00333651850.018
nucleotide catabolic processGO:00091662170.018
peptidyl amino acid modificationGO:00181933360.018
small gtpase mediated signal transductionGO:0007264970.018
ras protein signal transductionGO:0007265770.018
cytoplasmic transportGO:00164822340.018
macromolecule catabolic processGO:00090572810.018
small molecule biosynthetic processGO:00442831320.018
cellular carbohydrate metabolic processGO:00442621190.017
carbohydrate derivative catabolic processGO:19011362310.017
positive regulation of cell deathGO:00109422240.017
cell type specific apoptotic processGO:00972852680.017
Rat
positive regulation of programmed cell deathGO:00430682180.017
ribonucleoside catabolic processGO:00424542060.017
sulfur compound metabolic processGO:00067901000.017
fat cell differentiationGO:00454441600.017
intracellular protein transportGO:00068862040.017
cellular response to hormone stimulusGO:00328701500.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
purine ribonucleoside catabolic processGO:00461302050.017
organonitrogen compound biosynthetic processGO:19015661920.016
homeostasis of number of cellsGO:00488722100.016
maintenance of locationGO:0051235890.016
microtubule based processGO:00070172360.016
dephosphorylationGO:00163111290.016
regulation of hormone levelsGO:00108172110.016
spermatogenesisGO:00072832840.016
organic hydroxy compound metabolic processGO:19016152030.016
reactive oxygen species metabolic processGO:0072593840.016
Human
positive regulation of protein phosphorylationGO:00019342420.016
cell adhesionGO:00071553290.016
carbohydrate derivative biosynthetic processGO:19011371830.015
sensory perceptionGO:00076002450.015
nucleoside phosphate catabolic processGO:19012922220.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
generation of precursor metabolites and energyGO:00060911030.015
inflammatory responseGO:00069542440.015
regulation of cellular catabolic processGO:00313292420.015
regulation of cellular component biogenesisGO:00440871810.015
hexose metabolic processGO:0019318980.015
ribonucleotide catabolic processGO:00092612080.015
regulation of apoptotic signaling pathwayGO:20012331970.015
rho protein signal transductionGO:0007266320.015
cellular homeostasisGO:00197252400.015
regulation of hydrolase activityGO:00513362460.015
purine ribonucleotide catabolic processGO:00091542080.015
purine nucleoside catabolic processGO:00061522050.015
regulation of membrane potentialGO:00423911920.015
protein maturationGO:00516041760.015
energy derivation by oxidation of organic compoundsGO:0015980770.015
immune effector processGO:00022523210.015
mitochondrion organizationGO:00070051340.015
sensory organ morphogenesisGO:00905962420.015
germ cell developmentGO:00072811850.015
regulation of protein localizationGO:00328802310.014
nucleoside catabolic processGO:00091642060.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
glycosyl compound catabolic processGO:19016582060.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
regulation of kinase activityGO:00435492490.014
membrane organizationGO:00610242450.014
response to organic cyclic compoundGO:00140701980.014
gland developmentGO:00487323300.014
cellular response to organonitrogen compoundGO:00714171450.014
regulation of homeostatic processGO:00328441820.014
multicellular organismal signalingGO:0035637910.014
carbohydrate homeostasisGO:00335001280.014
positive regulation of cell activationGO:00508671580.014
regulation of neuron differentiationGO:00456642810.014
negative regulation of cellular protein metabolic processGO:00322692470.014
coenzyme a metabolic processGO:001593680.014
skeletal system developmentGO:00015013560.014
cofactor metabolic processGO:0051186800.014
regulation of lymphocyte activationGO:00512492400.013
negative regulation of cellular component organizationGO:00511291940.013
positive regulation of cell developmentGO:00107202370.013
regulation of protein kinase activityGO:00458592320.013
muscle tissue developmentGO:00605373080.013
myeloid cell differentiationGO:00300992330.013
regulation of establishment of protein localizationGO:00702011810.013
protein targetingGO:00066051430.013
renal system developmentGO:00720012250.013
leukocyte differentiationGO:00025213420.013
regulation of secretion by cellGO:19035302490.013
regulation of secretionGO:00510462740.013
cellular response to lipidGO:00713961450.013
purine containing compound catabolic processGO:00725232130.013
cellular macromolecule catabolic processGO:00442652060.013
ribonucleoside bisphosphate metabolic processGO:003387590.013
regulation of cell motilityGO:20001452360.013
cellular protein complex assemblyGO:00436231160.013
positive regulation of organelle organizationGO:00106381280.013
synaptic transmissionGO:00072683290.013
response to lipopolysaccharideGO:00324961280.013
myeloid leukocyte differentiationGO:00025731190.013
purine nucleotide catabolic processGO:00061952110.013
negative regulation of molecular functionGO:00440922580.013
regulation of transferase activityGO:00513382630.013
neuronal action potentialGO:0019228540.013
positive regulation of apoptotic processGO:00430652170.013
positive regulation of hydrolase activityGO:00513451480.012
organelle localizationGO:00516401790.012
mapk cascadeGO:00001652810.012
cellular chemical homeostasisGO:00550822150.012
epithelial tube morphogenesisGO:00605623030.012
regulation of cytokine productionGO:00018172660.012
nucleoside triphosphate catabolic processGO:00091432050.012
response to nutrient levelsGO:00316671090.012
Rat
positive regulation of lymphocyte activationGO:00512511400.012
camera type eye developmentGO:00430102660.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
action potentialGO:0001508780.012
regulation of cell projection organizationGO:00313442060.012
cation transportGO:00068123990.012
transmission of nerve impulseGO:0019226760.012
negative regulation of cell proliferationGO:00082852960.012
g protein coupled receptor signaling pathwayGO:00071862430.012
regulation of cell cycleGO:00517262810.012
translationGO:0006412930.012
establishment of protein localization to organelleGO:00725941180.012
chromatin organizationGO:00063252060.012
striated muscle tissue developmentGO:00147062930.012
ear developmentGO:00435832000.012
hematopoietic progenitor cell differentiationGO:00022441430.012
multicellular organismal homeostasisGO:00488711640.012
regulation of defense responseGO:00313472330.012
coenzyme biosynthetic processGO:0009108230.012
cellular response to cytokine stimulusGO:00713451890.012
negative regulation of protein metabolic processGO:00512482820.012
organelle fissionGO:00482851700.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
cellular response to organic cyclic compoundGO:0071407870.011
tube formationGO:00351481400.011
meiotic cell cycleGO:00513211220.011
blood vessel morphogenesisGO:00485142850.011
ion transmembrane transportGO:00342203610.011
embryonic organ morphogenesisGO:00485622760.011
cation transmembrane transportGO:00986552660.011
t cell activationGO:00421102890.011
organophosphate biosynthetic processGO:00904071220.011
positive regulation of protein kinase activityGO:00458601440.011
muscle cell differentiationGO:00426922610.011
response to inorganic substanceGO:0010035960.011
glucose homeostasisGO:00425931280.011
rhythmic processGO:00485111740.011
regulation of lipid metabolic processGO:00192161180.011
carboxylic acid catabolic processGO:0046395510.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
Human
skin developmentGO:00435882200.011
locomotory behaviorGO:00076261950.011
cell substrate adhesionGO:00315891300.011
regulation of t cell activationGO:00508631700.011
regulation of cell cycle processGO:00105641600.011
protein catabolic processGO:00301632210.011
inorganic ion transmembrane transportGO:00986602340.011
regulation of proteolysisGO:00301621640.011
amide transportGO:00428861380.011
negative regulation of immune system processGO:00026832090.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
guanosine containing compound metabolic processGO:19010681440.011
response to molecule of bacterial originGO:00022371430.011
ossificationGO:00015032160.011
cellular response to dna damage stimulusGO:00069742070.011
negative regulation of intracellular signal transductionGO:19025321670.011
anatomical structure homeostasisGO:00602491450.011
cofactor biosynthetic processGO:0051188410.011
regulation of purine nucleotide metabolic processGO:19005421690.011
innate immune responseGO:00450871570.011
response to growth factorGO:00708481980.011
cellular response to acid chemicalGO:0071229680.011
negative regulation of phosphate metabolic processGO:00459361840.011
positive regulation of nervous system developmentGO:00519622210.011
anion transportGO:00068201770.011
organic acid catabolic processGO:0016054510.011
morphogenesis of embryonic epitheliumGO:00163311590.011
organic acid biosynthetic processGO:0016053860.011
response to peptideGO:19016521360.011
developmental maturationGO:00217001930.010
regulation of mapk cascadeGO:00434082480.010
response to oxidative stressGO:00069791230.010
forebrain developmentGO:00309003020.010
multicellular organism growthGO:00352641610.010
hormone secretionGO:00468791280.010
sequestering of metal ionGO:0051238190.010
methylationGO:00322591340.010
guanosine containing compound catabolic processGO:19010691440.010
intracellular mrna localizationGO:000829840.010
regulation of nucleoside metabolic processGO:00091181300.010
chemotaxisGO:00069352470.010
regulation of interleukin 8 productionGO:003267730.010
compound eye developmentGO:004874910.010
nuclear divisionGO:00002801580.010
protein oligomerizationGO:0051259670.010
embryonic epithelial tube formationGO:00018381300.010

Sirt5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.027
nervous system diseaseDOID:86300.020
disease of anatomical entityDOID:700.020
inherited metabolic disorderDOID:65500.019
central nervous system diseaseDOID:33100.015
immune system diseaseDOID:291400.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
organ system cancerDOID:005068600.011
musculoskeletal system diseaseDOID:1700.011
cardiovascular system diseaseDOID:128700.010
sensory system diseaseDOID:005015500.010
hematopoietic system diseaseDOID:7400.010
amino acid metabolic disorderDOID:925200.010