IMP: Integrative Multi-species Prediction

Mus musculus

187 known processes

Sox10

SRY-box containing gene 10

(Aliases: Sox21,Dom)

Ensembl: ENSMUSG00000033006
Entrez: 20665
UniProtKB: Q04888

Process Predictions
Disease Predictions

Sox10 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
negative regulation of neuron differentiation	GO:0045665	101	0.992	Mouse
amine metabolic process	GO:0009308	45	0.988
pigmentation	GO:0043473	71	0.974
glial cell differentiation	GO:0010001	131	0.973
cellular amine metabolic process	GO:0044106	44	0.969
peripheral nervous system development	GO:0007422	53	0.965
sympathetic nervous system development	GO:0048485	22	0.956	Mouse
autonomic nervous system development	GO:0048483	43	0.950
mesenchymal cell differentiation	GO:0048762	107	0.947
schwann cell development	GO:0014044	22	0.938
glial cell development	GO:0021782	54	0.936	Mouse
neural crest cell migration	GO:0001755	32	0.933
regulation of ras gtpase activity	GO:0032318	88	0.926
regulation of cellular amine metabolic process	GO:0033238	20	0.910
gliogenesis	GO:0042063	141	0.909
skeletal system development	GO:0001501	356	0.890	Mouse
ureteric bud morphogenesis	GO:0060675	62	0.890	Mouse
striated muscle tissue development	GO:0014706	293	0.883	Mouse
ras protein signal transduction	GO:0007265	77	0.882
enteric nervous system development	GO:0048484	11	0.878
limb development	GO:0060173	166	0.870	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.867
lateral line nerve development	GO:0048892	1	0.859
developmental pigmentation	GO:0048066	40	0.854
cell proliferation in hindbrain	GO:0021534	10	0.845
sensory system development	GO:0048880	3	0.837
positive regulation of nervous system development	GO:0051962	221	0.837
regulation of purine nucleotide catabolic process	GO:0033121	122	0.833
muscle tissue development	GO:0060537	308	0.833	Mouse
ameboidal type cell migration	GO:0001667	128	0.832
positive regulation of neuron differentiation	GO:0045666	141	0.817	Mouse
regulation of neuron differentiation	GO:0045664	281	0.817	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.811	Mouse
central nervous system morphogenesis	GO:0021551	2	0.798
stem cell development	GO:0048864	219	0.794
cerebral cortex development	GO:0021987	86	0.786	Mouse
neuroepithelial cell differentiation	GO:0060563	37	0.776
negative regulation of neuron projection development	GO:0010977	50	0.770
gtp metabolic process	GO:0046039	144	0.765
cerebellar granule cell precursor proliferation	GO:0021930	10	0.764
activation of transmembrane receptor protein tyrosine kinase activity	GO:0007171	3	0.763
synaptic transmission	GO:0007268	329	0.759
neuron projection guidance	GO:0097485	141	0.750
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.748
telencephalon development	GO:0021537	186	0.742	Mouse
skeletal muscle organ development	GO:0060538	163	0.734	Mouse
cell type specific apoptotic process	GO:0097285	268	0.731	Mouse
cation transport	GO:0006812	399	0.730
axon guidance	GO:0007411	141	0.726
cellular amino acid metabolic process	GO:0006520	103	0.724
heart trabecula morphogenesis	GO:0061384	26	0.723
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.721
nephron tubule morphogenesis	GO:0072078	68	0.720	Mouse
developmental cell growth	GO:0048588	84	0.720	Mouse
cellular ketone metabolic process	GO:0042180	84	0.717
regulation of cell motility	GO:2000145	236	0.717	Mouse
nephron development	GO:0072006	109	0.714	Mouse
regulation of neuron projection development	GO:0010975	169	0.710
regulation of membrane potential	GO:0042391	192	0.708
neural crest cell development	GO:0014032	48	0.690
rho protein signal transduction	GO:0007266	32	0.686
embryonic organ morphogenesis	GO:0048562	276	0.676	Mouse
chemotaxis	GO:0006935	247	0.675
nucleotide catabolic process	GO:0009166	217	0.668
connective tissue development	GO:0061448	179	0.655	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.649
lateral line system development	GO:0048925	1	0.649
cell growth	GO:0016049	130	0.647	Mouse
smoothened signaling pathway	GO:0007224	105	0.643
regulation of nucleoside metabolic process	GO:0009118	130	0.635
regulation of ras protein signal transduction	GO:0046578	114	0.633
forebrain cell migration	GO:0021885	58	0.630
hindbrain tangential cell migration	GO:0021934	2	0.625
negative regulation of cell development	GO:0010721	169	0.622	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	5	0.620
myelination in peripheral nervous system	GO:0022011	19	0.618
negative regulation of cell migration	GO:0030336	59	0.617
peptidyl tyrosine phosphorylation	GO:0018108	143	0.612
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.611
skin development	GO:0043588	220	0.607	Mouse
stem cell differentiation	GO:0048863	268	0.607
regulation of gtp catabolic process	GO:0033124	113	0.605
glycosyl compound catabolic process	GO:1901658	206	0.600
kidney development	GO:0001822	213	0.600	Mouse
cranial nerve development	GO:0021545	41	0.600
purine ribonucleoside catabolic process	GO:0046130	205	0.597
purine nucleoside catabolic process	GO:0006152	205	0.597
metanephros development	GO:0001656	79	0.592	Mouse
nucleoside triphosphate metabolic process	GO:0009141	230	0.592
ribonucleotide catabolic process	GO:0009261	208	0.591
pallium development	GO:0021543	120	0.588	Mouse
hindbrain development	GO:0030902	128	0.587
gtp catabolic process	GO:0006184	143	0.579
mesenchymal cell development	GO:0014031	93	0.578
mesenchyme development	GO:0060485	152	0.577
neural crest cell differentiation	GO:0014033	54	0.576
positive regulation of gtpase activity	GO:0043547	85	0.568
nucleobase containing small molecule metabolic process	GO:0055086	352	0.566
astrocyte differentiation	GO:0048708	43	0.563	Mouse
guanosine containing compound metabolic process	GO:1901068	144	0.558
positive regulation of nucleotide catabolic process	GO:0030813	88	0.558
hair follicle development	GO:0001942	85	0.556	Mouse
extracellular structure organization	GO:0043062	148	0.553	Mouse
regulation of apoptotic signaling pathway	GO:2001233	197	0.552
regulation of rho protein signal transduction	GO:0035023	71	0.552
regulation of cellular ketone metabolic process	GO:0010565	66	0.551
negative regulation of nervous system development	GO:0051961	156	0.550	Mouse
signal transduction in absence of ligand	GO:0038034	55	0.548
axonogenesis	GO:0007409	274	0.545
regulation of gliogenesis	GO:0014013	50	0.537
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.536
regulation of neuron death	GO:1901214	134	0.529
dopamine metabolic process	GO:0042417	23	0.527
regulation of rho gtpase activity	GO:0032319	58	0.519
regulation of renal sodium excretion	GO:0035813	3	0.517
digestive system development	GO:0055123	200	0.513
regulation of axon extension	GO:0030516	43	0.512
ear development	GO:0043583	200	0.512	Mouse
guanosine containing compound catabolic process	GO:1901069	144	0.507
positive regulation of gtp catabolic process	GO:0033126	85	0.504
spinal cord development	GO:0021510	81	0.503	Mouse
excretion	GO:0007588	22	0.502
carbohydrate homeostasis	GO:0033500	128	0.501	Mouse
muscle cell differentiation	GO:0042692	261	0.500	Mouse
cell adhesion	GO:0007155	329	0.499	Mouse
organ growth	GO:0035265	117	0.496	Mouse
forebrain neuron differentiation	GO:0021879	52	0.494	Mouse
nucleoside phosphate metabolic process	GO:0006753	338	0.483
stem cell maintenance	GO:0019827	130	0.482	Mouse
positive regulation of nucleoside metabolic process	GO:0045979	91	0.480
organonitrogen compound catabolic process	GO:1901565	264	0.478
regulation of nucleotide catabolic process	GO:0030811	122	0.477
aromatic compound catabolic process	GO:0019439	286	0.472
negative regulation of neuron apoptotic process	GO:0043524	92	0.471
regulation of cell migration	GO:0030334	219	0.471	Mouse
negative regulation of neuron death	GO:1901215	98	0.465
kidney epithelium development	GO:0072073	121	0.464	Mouse
epidermis development	GO:0008544	187	0.460	Mouse
ossification	GO:0001503	216	0.458	Mouse
renal tubule development	GO:0061326	87	0.450	Mouse
telencephalon cell migration	GO:0022029	55	0.450
neuron maturation	GO:0042551	29	0.448
schwann cell differentiation	GO:0014037	26	0.445
regulation of kinase activity	GO:0043549	249	0.444
nucleoside metabolic process	GO:0009116	246	0.435
myeloid cell homeostasis	GO:0002262	114	0.430
cellular response to growth factor stimulus	GO:0071363	197	0.428	Mouse
mechanoreceptor differentiation	GO:0042490	67	0.427
neuron projection extension	GO:1990138	64	0.425
learning	GO:0007612	98	0.425
epithelial cell proliferation	GO:0050673	174	0.422	Mouse
carbohydrate derivative catabolic process	GO:1901136	231	0.421
wound healing	GO:0042060	157	0.418	Mouse
myelination	GO:0042552	74	0.413
response to pain	GO:0048265	26	0.410
regulation of protein kinase activity	GO:0045859	232	0.409
regulation of ph	GO:0006885	26	0.408
nucleoside triphosphate catabolic process	GO:0009143	205	0.405
mapk cascade	GO:0000165	281	0.400	Mouse
regulation of protein transport	GO:0051223	163	0.398
regulation of purine nucleotide metabolic process	GO:1900542	169	0.396
ribose phosphate metabolic process	GO:0019693	291	0.395
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.394
regulation of cell projection organization	GO:0031344	206	0.391
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.391
axon ensheathment	GO:0008366	76	0.391
organonitrogen compound biosynthetic process	GO:1901566	192	0.389
sensory organ morphogenesis	GO:0090596	242	0.386	Mouse
neuron apoptotic process	GO:0051402	142	0.383
regulation of glial cell differentiation	GO:0045685	41	0.380
positive regulation of protein modification process	GO:0031401	299	0.379	Mouse
endothelium development	GO:0003158	45	0.378	Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.375
negative regulation of leukocyte differentiation	GO:1902106	51	0.373
organophosphate catabolic process	GO:0046434	232	0.369
negative regulation of protein metabolic process	GO:0051248	282	0.367
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.366
nucleoside catabolic process	GO:0009164	206	0.365
positive regulation of ras gtpase activity	GO:0032320	65	0.364
carbohydrate transport	GO:0008643	62	0.364
positive regulation of epithelial cell proliferation	GO:0050679	68	0.361	Mouse
glucose transport	GO:0015758	56	0.360
cellular nitrogen compound catabolic process	GO:0044270	280	0.357
forebrain development	GO:0030900	302	0.352	Mouse
extracellular matrix organization	GO:0030198	147	0.351	Mouse
ribonucleotide metabolic process	GO:0009259	291	0.351
synapse assembly	GO:0007416	56	0.348
epithelial tube formation	GO:0072175	130	0.348	Mouse
granulocyte macrophage colony stimulating factor production	GO:0032604	3	0.347
purine ribonucleoside metabolic process	GO:0046128	241	0.345
regulation of astrocyte differentiation	GO:0048710	20	0.343
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.341
pigment cell differentiation	GO:0050931	27	0.339
purine containing compound metabolic process	GO:0072521	311	0.335
peptidyl tyrosine modification	GO:0018212	145	0.335
cell proliferation in external granule layer	GO:0021924	10	0.334
oligodendrocyte differentiation	GO:0048709	53	0.332
nerve development	GO:0021675	67	0.326
purine nucleotide metabolic process	GO:0006163	302	0.325
cell migration in hindbrain	GO:0021535	16	0.324
trabecula morphogenesis	GO:0061383	40	0.322
positive regulation of cell development	GO:0010720	237	0.322
peripheral nervous system neuron axonogenesis	GO:0048936	3	0.318
negative regulation of cell proliferation	GO:0008285	296	0.317	Mouse
extrinsic apoptotic signaling pathway	GO:0097191	126	0.317
neuron death	GO:0070997	154	0.316
organic cyclic compound catabolic process	GO:1901361	295	0.315
positive regulation of nucleotide metabolic process	GO:0045981	114	0.313
regulation of leukocyte differentiation	GO:1902105	159	0.313
purine nucleoside metabolic process	GO:0042278	241	0.312
ribonucleoside catabolic process	GO:0042454	206	0.310
paramesonephric duct development	GO:0061205	3	0.308
muscle tissue morphogenesis	GO:0060415	53	0.308
ureteric bud development	GO:0001657	94	0.304	Mouse
inner ear receptor cell differentiation	GO:0060113	61	0.300
response to organonitrogen compound	GO:0010243	246	0.295	Mouse
circulatory system process	GO:0003013	197	0.294
nucleoside phosphate catabolic process	GO:1901292	222	0.293
neuroblast proliferation	GO:0007405	49	0.289
myeloid cell differentiation	GO:0030099	233	0.286
mesenchymal cell proliferation	GO:0010463	44	0.283	Mouse
regulation of protein tyrosine kinase activity	GO:0061097	17	0.281
regulation of cell activation	GO:0050865	289	0.280	Mouse
regulation of extent of cell growth	GO:0061387	52	0.280
neuronal action potential	GO:0019228	54	0.279
glycosyl compound metabolic process	GO:1901657	246	0.278
odontogenesis	GO:0042476	78	0.278
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.277
central nervous system neuron differentiation	GO:0021953	162	0.275	Mouse
synapse organization	GO:0050808	125	0.274
cardiac muscle cell differentiation	GO:0055007	69	0.273
tube formation	GO:0035148	140	0.270	Mouse
single organism cell adhesion	GO:0098602	156	0.268	Mouse
negative regulation of gliogenesis	GO:0014014	23	0.267	Mouse
regulation of anatomical structure size	GO:0090066	178	0.265
regulation of cellular component size	GO:0032535	121	0.264
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.264
striated muscle cell proliferation	GO:0014855	39	0.263
associative learning	GO:0008306	61	0.261
developmental induction	GO:0031128	34	0.259	Mouse
positive regulation of striated muscle tissue development	GO:0045844	31	0.257	Mouse
cognition	GO:0050890	149	0.257
somatic stem cell maintenance	GO:0035019	47	0.257	Mouse
positive regulation of map kinase activity	GO:0043406	84	0.254
muscle system process	GO:0003012	141	0.253
pituitary gland development	GO:0021983	38	0.247	Mouse
extrinsic apoptotic signaling pathway in absence of ligand	GO:0097192	55	0.245
ensheathment of neurons	GO:0007272	76	0.245
negative regulation of cell motility	GO:2000146	61	0.243
positive regulation of protein phosphorylation	GO:0001934	242	0.243	Mouse
male sex differentiation	GO:0046661	109	0.241	Mouse
negative regulation of cell projection organization	GO:0031345	56	0.240
appendage development	GO:0048736	166	0.238	Mouse
purine nucleotide catabolic process	GO:0006195	211	0.238
embryonic skeletal system development	GO:0048706	120	0.238	Mouse
purine ribonucleotide metabolic process	GO:0009150	290	0.237
neuromuscular process	GO:0050905	99	0.236	Mouse
regulation of fibroblast proliferation	GO:0048145	34	0.235
response to oxidative stress	GO:0006979	123	0.233
regulation of morphogenesis of a branching structure	GO:0060688	53	0.232	Mouse
regulation of cell adhesion	GO:0030155	154	0.231	Mouse
developmental maturation	GO:0021700	193	0.230
single organismal cell cell adhesion	GO:0016337	131	0.229	Mouse
positive regulation of granulocyte macrophage colony stimulating factor production	GO:0032725	3	0.228
negative regulation of immune system process	GO:0002683	209	0.227	Mouse
regulation of t cell differentiation	GO:0045580	83	0.226
heterocycle catabolic process	GO:0046700	280	0.226
mesonephric tubule morphogenesis	GO:0072171	63	0.226	Mouse
trigeminal nerve development	GO:0021559	10	0.225
cellular response to oxidative stress	GO:0034599	76	0.225
gland development	GO:0048732	330	0.224	Mouse
development of primary sexual characteristics	GO:0045137	143	0.223	Mouse
nephron tubule development	GO:0072080	84	0.222	Mouse
ear morphogenesis	GO:0042471	118	0.218	Mouse
glucose homeostasis	GO:0042593	128	0.217	Mouse
intermediate filament cytoskeleton organization	GO:0045104	26	0.216
nucleotide metabolic process	GO:0009117	332	0.216
olfactory bulb interneuron differentiation	GO:0021889	12	0.215
morphogenesis of a branching epithelium	GO:0061138	193	0.211	Mouse
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.210
regulation of neuron apoptotic process	GO:0043523	122	0.210
positive regulation of cerebellar granule cell precursor proliferation	GO:0021940	10	0.208
tissue remodeling	GO:0048771	102	0.207
t cell activation	GO:0042110	289	0.205	Mouse
hexose transport	GO:0008645	56	0.204
heart process	GO:0003015	94	0.203
monosaccharide transport	GO:0015749	58	0.203
regulation of heart contraction	GO:0008016	77	0.200
regulation of cerebellar granule cell precursor proliferation	GO:0021936	12	0.199
regulation of epithelial cell proliferation	GO:0050678	141	0.198	Mouse
multicellular organismal response to stress	GO:0033555	62	0.198
protein localization to nucleus	GO:0034504	121	0.197	Mouse
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	GO:0072108	3	0.197
neural tube formation	GO:0001841	108	0.196	Mouse
regulation of nucleotide metabolic process	GO:0006140	169	0.194
heart trabecula formation	GO:0060347	14	0.192
cranial nerve morphogenesis	GO:0021602	26	0.192
cerebral cortex cell migration	GO:0021795	44	0.192
negative regulation of wnt signaling pathway	GO:0030178	73	0.192
cellular homeostasis	GO:0019725	240	0.191	Mouse
action potential	GO:0001508	78	0.191
cartilage development	GO:0051216	140	0.191	Mouse
positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	18	0.191	Mouse
respiratory gaseous exchange	GO:0007585	43	0.190
embryonic camera type eye development	GO:0031076	36	0.190	Mouse
regulation of blood pressure	GO:0008217	93	0.188
embryonic epithelial tube formation	GO:0001838	130	0.188	Mouse
brain morphogenesis	GO:0048854	32	0.187	Mouse
postganglionic parasympathetic nervous system development	GO:0021784	2	0.184
cation transmembrane transport	GO:0098655	266	0.178
respiratory system development	GO:0060541	190	0.178	Mouse
multicellular organismal signaling	GO:0035637	91	0.178
lymphocyte differentiation	GO:0030098	242	0.177	Mouse
renal sodium excretion	GO:0035812	3	0.176
negative regulation of protein modification process	GO:0031400	163	0.176
ribonucleoside metabolic process	GO:0009119	245	0.175
hematopoietic progenitor cell differentiation	GO:0002244	143	0.174	Mouse
gonad development	GO:0008406	141	0.174	Mouse
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.173
peptidyl amino acid modification	GO:0018193	336	0.172
sphingolipid metabolic process	GO:0006665	45	0.172
purine ribonucleotide catabolic process	GO:0009154	208	0.171
regulation of metal ion transport	GO:0010959	106	0.168
positive regulation of glial cell proliferation	GO:0060252	4	0.168
g protein coupled receptor signaling pathway	GO:0007186	243	0.168
regulation of cell size	GO:0008361	72	0.167
positive regulation of hydrolase activity	GO:0051345	148	0.167
cellular response to monosaccharide stimulus	GO:0071326	47	0.166	Mouse
hair follicle morphogenesis	GO:0031069	29	0.166
regulation of cellular component biogenesis	GO:0044087	181	0.164	Mouse
renal system development	GO:0072001	225	0.164	Mouse
midbrain development	GO:0030901	35	0.164
regulation of cellular catabolic process	GO:0031329	242	0.163
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.163
protein localization to membrane	GO:0072657	108	0.162
positive regulation of notch signaling pathway	GO:0045747	18	0.161	Mouse
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.161
metanephric nephron development	GO:0072210	34	0.161	Mouse
apoptotic signaling pathway	GO:0097190	306	0.160
learning or memory	GO:0007611	148	0.159
somatotropin secreting cell differentiation	GO:0060126	4	0.159
astrocyte development	GO:0014002	12	0.158
retina development in camera type eye	GO:0060041	119	0.158	Mouse
forebrain morphogenesis	GO:0048853	17	0.158	Mouse
cell chemotaxis	GO:0060326	81	0.157
positive regulation of cellular catabolic process	GO:0031331	148	0.156
lymphocyte proliferation	GO:0046651	164	0.154
regulation of mesenchymal cell proliferation	GO:0010464	37	0.154	Mouse
endothelial cell differentiation	GO:0045446	41	0.152	Mouse
regulation of developmental pigmentation	GO:0048070	14	0.150
t cell proliferation	GO:0042098	120	0.149
developmental growth involved in morphogenesis	GO:0060560	138	0.149	Mouse
positive regulation of cell migration	GO:0030335	109	0.148	Mouse
positive regulation of protein kinase b signaling	GO:0051897	32	0.147
regulation of smoothened signaling pathway	GO:0008589	58	0.147
regulation of map kinase activity	GO:0043405	120	0.147
epithelial tube morphogenesis	GO:0060562	303	0.146	Mouse
female gonad development	GO:0008585	71	0.146
skeletal muscle cell differentiation	GO:0035914	66	0.146	Mouse
positive regulation of rho gtpase activity	GO:0032321	41	0.146
regulation of hydrolase activity	GO:0051336	246	0.145
positive regulation of transferase activity	GO:0051347	167	0.145
positive regulation of smooth muscle cell migration	GO:0014911	4	0.144
t cell differentiation	GO:0030217	174	0.144	Mouse
positive regulation of protein kinase activity	GO:0045860	144	0.142
regulation of cytoskeleton organization	GO:0051493	122	0.142
cell maturation	GO:0048469	127	0.141
development of primary male sexual characteristics	GO:0046546	88	0.139	Mouse
optic nerve structural organization	GO:0021633	2	0.138
regulation of kidney development	GO:0090183	40	0.137	Mouse
protein localization to organelle	GO:0033365	185	0.137	Mouse
transmission of nerve impulse	GO:0019226	76	0.136
cardiac muscle tissue morphogenesis	GO:0055008	44	0.136
positive regulation of endothelial cell proliferation	GO:0001938	17	0.135
cerebellar cortex formation	GO:0021697	22	0.135
dendrite development	GO:0016358	115	0.135
peptide secretion	GO:0002790	114	0.134	Mouse
rac protein signal transduction	GO:0016601	13	0.134
optic nerve morphogenesis	GO:0021631	6	0.133
regeneration	GO:0031099	38	0.133	Mouse
cardiocyte differentiation	GO:0035051	87	0.132	Mouse
sensory perception of mechanical stimulus	GO:0050954	107	0.132	Mouse
dorsal spinal cord development	GO:0021516	20	0.132
sensory perception	GO:0007600	245	0.131	Mouse
bmp signaling pathway	GO:0030509	93	0.131	Mouse
glial cell fate specification	GO:0021780	5	0.130
metanephric dct cell differentiation	GO:0072240	3	0.130
cardiac chamber development	GO:0003205	108	0.130	Mouse
melanocyte differentiation	GO:0030318	25	0.129
phosphatidylinositol mediated signaling	GO:0048015	41	0.128	Mouse
lateral motor column neuron migration	GO:0097477	3	0.128
multicellular organismal homeostasis	GO:0048871	164	0.128	Mouse
positive regulation of heart growth	GO:0060421	18	0.127
negative regulation of lymphocyte activation	GO:0051250	91	0.127
cardiac muscle tissue development	GO:0048738	130	0.127
regulation of excretion	GO:0044062	5	0.126
regulation of lymphocyte proliferation	GO:0050670	117	0.126
negative regulation of ossification	GO:0030279	49	0.126	Mouse
skeletal system morphogenesis	GO:0048705	203	0.125	Mouse
detection of stimulus	GO:0051606	84	0.125	Mouse
cellular response to insulin stimulus	GO:0032869	78	0.125
motor neuron migration	GO:0097475	4	0.124
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001240	16	0.124
regulation of phosphatidylinositol 3 kinase signaling	GO:0014066	30	0.123	Mouse
regulation of system process	GO:0044057	200	0.123
neural tube development	GO:0021915	160	0.123	Mouse
regulation of interleukin 6 production	GO:0032675	55	0.123
anatomical structure maturation	GO:0071695	49	0.123
tube closure	GO:0060606	91	0.122
vascular process in circulatory system	GO:0003018	62	0.122
regulation of transferase activity	GO:0051338	263	0.121
regulation of cardiac muscle cell proliferation	GO:0060043	23	0.121
negative regulation of phosphorylation	GO:0042326	166	0.121
regulation of transcription involved in cell fate commitment	GO:0060850	15	0.121	Mouse
response to insulin	GO:0032868	100	0.120
cardiac muscle cell proliferation	GO:0060038	31	0.120
nitrogen compound transport	GO:0071705	271	0.119	Mouse
regulation of establishment of protein localization	GO:0070201	181	0.119
developmental programmed cell death	GO:0010623	41	0.118
regulation of protein localization	GO:0032880	231	0.118
negative regulation of glial cell differentiation	GO:0045686	21	0.117
positive regulation of mapk cascade	GO:0043410	170	0.117
regulation of cardiac muscle tissue growth	GO:0055021	26	0.117
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.116	Mouse
platelet derived growth factor receptor alpha signaling pathway	GO:0035790	3	0.116
hair cycle	GO:0042633	90	0.114	Mouse
response to organic cyclic compound	GO:0014070	198	0.114
nuclear transport	GO:0051169	139	0.114
neuron migration	GO:0001764	122	0.113
spinal cord motor neuron differentiation	GO:0021522	35	0.113	Mouse
regulation of ion homeostasis	GO:2000021	64	0.112
positive regulation of muscle tissue development	GO:1901863	32	0.110	Mouse
sensory perception of sound	GO:0007605	97	0.110	Mouse
central nervous system neuron axonogenesis	GO:0021955	28	0.108
organic hydroxy compound metabolic process	GO:1901615	203	0.108
hippocampus development	GO:0021766	52	0.108
ion transmembrane transport	GO:0034220	361	0.108
regulation of erk1 and erk2 cascade	GO:0070372	71	0.107
second messenger mediated signaling	GO:0019932	73	0.107
medulla oblongata development	GO:0021550	3	0.107
lens development in camera type eye	GO:0002088	62	0.106	Mouse
forebrain generation of neurons	GO:0021872	63	0.106	Mouse
tissue homeostasis	GO:0001894	115	0.106	Mouse
cellular response to glucose stimulus	GO:0071333	45	0.105	Mouse
negative regulation of cellular protein metabolic process	GO:0032269	247	0.105
homeostasis of number of cells	GO:0048872	210	0.105	Mouse
molting cycle	GO:0042303	90	0.104	Mouse
sensory perception of pain	GO:0019233	47	0.103
regulation of skeletal muscle fiber development	GO:0048742	36	0.102	Mouse
chondrocyte differentiation	GO:0002062	72	0.102	Mouse
cellular response to organonitrogen compound	GO:0071417	145	0.101	Mouse
inorganic ion transmembrane transport	GO:0098660	234	0.101
purine containing compound catabolic process	GO:0072523	213	0.101
membrane fusion	GO:0061025	38	0.100
regulation of organ growth	GO:0046620	61	0.100
negative regulation of phosphorus metabolic process	GO:0010563	184	0.100
leukocyte proliferation	GO:0070661	172	0.099
pigment metabolic process	GO:0042440	32	0.098	Mouse
cell differentiation in hindbrain	GO:0021533	24	0.097
positive regulation of neuron projection development	GO:0010976	79	0.096
divalent inorganic cation transport	GO:0072511	178	0.096
regulation of pigment cell differentiation	GO:0050932	7	0.095
positive regulation of protein tyrosine kinase activity	GO:0061098	10	0.095
notch signaling pathway	GO:0007219	71	0.095	Mouse
calcium ion transport	GO:0006816	159	0.094
positive regulation of ras protein signal transduction	GO:0046579	13	0.094
dopaminergic neuron differentiation	GO:0071542	14	0.094
maintenance of location	GO:0051235	89	0.094
regulation of metanephros development	GO:0072215	15	0.093
hair cell differentiation	GO:0035315	40	0.092
positive regulation of secretion by cell	GO:1903532	114	0.092	Mouse
peptidyl serine phosphorylation	GO:0018105	74	0.091
insulin secretion	GO:0030073	89	0.091	Mouse
negative regulation of phosphate metabolic process	GO:0045936	184	0.091
regulation of synaptic plasticity	GO:0048167	87	0.091
neural crest cell migration involved in autonomic nervous system development	GO:1901166	5	0.091
response to peptide	GO:1901652	136	0.091
cytokine production	GO:0001816	319	0.091
positive regulation of mesenchymal cell proliferation	GO:0002053	33	0.091	Mouse
bone morphogenesis	GO:0060349	78	0.090	Mouse
response to growth factor	GO:0070848	198	0.090	Mouse
serotonin transport	GO:0006837	11	0.090
establishment of neuroblast polarity	GO:0045200	1	0.090
camp metabolic process	GO:0046058	40	0.089
regulation of intracellular transport	GO:0032386	159	0.089
regulation of cytokine production	GO:0001817	266	0.089
regulation of cell cycle process	GO:0010564	160	0.089	Mouse
regulation of heart growth	GO:0060420	31	0.089
cell fate specification	GO:0001708	72	0.088	Mouse
salivary gland morphogenesis	GO:0007435	33	0.088

Sox10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.382
cancer	DOID:162	0.212
organ system cancer	DOID:0050686	0.212
disease of anatomical entity	DOID:7	0.203
gastrointestinal system disease	DOID:77	0.203

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