| regulation of cell cycle | GO:0051726 | 281 | 0.282 | |
| rna splicing via transesterification reactions | GO:0000375 | 43 | 0.272 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.267 | |
| mrna splicing via spliceosome | GO:0000398 | 43 | 0.229 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.200 | |
| cell division | GO:0051301 | 120 | 0.146 | |
| male gamete generation | GO:0048232 | 285 | 0.143 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 32 | 0.132 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.122 | |
| lateral inhibition | GO:0046331 | 1 | 0.106 | Fly |
| organelle fission | GO:0048285 | 170 | 0.104 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.104 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.096 | |
| nuclear division | GO:0000280 | 158 | 0.093 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.085 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.084 | |
| regulation of nuclear division | GO:0051783 | 56 | 0.084 | |
| mrna metabolic process | GO:0016071 | 84 | 0.083 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.079 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.078 | |
| microtubule based process | GO:0007017 | 236 | 0.073 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.070 | |
| oocyte construction | GO:0007308 | 2 | 0.068 | Fly |
| rna splicing | GO:0008380 | 54 | 0.068 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.068 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.064 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.064 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.063 | Mouse Fly |
| nucleoside metabolic process | GO:0009116 | 246 | 0.063 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.062 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.061 | |
| serine family amino acid metabolic process | GO:0009069 | 7 | 0.060 | |
| l serine metabolic process | GO:0006563 | 2 | 0.060 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 43 | 0.059 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.058 | |
| dna metabolic process | GO:0006259 | 303 | 0.057 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.056 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.055 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.055 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.055 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.054 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.054 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.053 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.053 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.051 | |
| regulation of cell division | GO:0051302 | 76 | 0.051 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.051 | |
| body morphogenesis | GO:0010171 | 45 | 0.049 | |
| oocyte axis specification | GO:0007309 | 2 | 0.049 | Fly |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.048 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.048 | |
| translation | GO:0006412 | 93 | 0.048 | Fly |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.047 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.047 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.047 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.047 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.046 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.046 | |
| germ cell development | GO:0007281 | 185 | 0.046 | Fly |
| positive regulation of chromosome segregation | GO:0051984 | 4 | 0.044 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.044 | |
| protein processing | GO:0016485 | 163 | 0.044 | |
| protein localization to organelle | GO:0033365 | 185 | 0.043 | |
| positive regulation of cell cycle | GO:0045787 | 92 | 0.042 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.041 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.041 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.040 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.039 | |
| positive regulation of mitotic sister chromatid separation | GO:1901970 | 2 | 0.038 | |
| dna repair | GO:0006281 | 107 | 0.038 | |
| positive regulation of mitotic metaphase anaphase transition | GO:0045842 | 2 | 0.037 | |
| regulation of mrna metabolic process | GO:1903311 | 43 | 0.037 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.036 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.035 | |
| mrna processing | GO:0006397 | 63 | 0.035 | |
| membrane organization | GO:0061024 | 245 | 0.034 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.034 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.034 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.033 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.033 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.032 | |
| dna recombination | GO:0006310 | 92 | 0.032 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.031 | |
| protein maturation | GO:0051604 | 176 | 0.031 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.030 | |
| compound eye development | GO:0048749 | 1 | 0.029 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.029 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.029 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.028 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.028 | |
| chromosome segregation | GO:0007059 | 48 | 0.028 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.028 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.027 | |
| regulation of cell activation | GO:0050865 | 289 | 0.026 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.026 | |
| chromatin organization | GO:0006325 | 206 | 0.026 | |
| immunoglobulin production | GO:0002377 | 73 | 0.026 | |
| stem cell development | GO:0048864 | 219 | 0.026 | Mouse |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.026 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.026 | |
| meiosis i | GO:0007127 | 60 | 0.026 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.025 | |
| histone methylation | GO:0016571 | 71 | 0.025 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.025 | |
| positive regulation of cell cycle phase transition | GO:1901989 | 17 | 0.025 | |
| alternative mrna splicing via spliceosome | GO:0000380 | 12 | 0.025 | |
| macromolecule methylation | GO:0043414 | 120 | 0.025 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.025 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.025 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.024 | |
| gonad morphogenesis | GO:0035262 | 1 | 0.023 | |
| purine nucleobase biosynthetic process | GO:0009113 | 3 | 0.023 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.023 | |
| locomotory behavior | GO:0007626 | 195 | 0.023 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.023 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.023 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.023 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.022 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.022 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.022 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.021 | |
| regulation of mitochondrion organization | GO:0010821 | 27 | 0.021 | |
| digestive tract development | GO:0048565 | 190 | 0.021 | |
| positive regulation of chromosome organization | GO:2001252 | 33 | 0.021 | |
| regulation of binding | GO:0051098 | 111 | 0.021 | |
| synaptic transmission | GO:0007268 | 329 | 0.021 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.021 | |
| regulation of defense response | GO:0031347 | 233 | 0.021 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.021 | |
| protein localization to cell junction | GO:1902414 | 3 | 0.021 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.021 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.021 | |
| somatic recombination of immunoglobulin gene segments | GO:0016447 | 42 | 0.020 | |
| spermatogenesis | GO:0007283 | 284 | 0.020 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.020 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.020 | |
| cell fate commitment | GO:0045165 | 210 | 0.020 | Fly |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.020 | Fly |
| positive regulation of mitotic cell cycle | GO:0045931 | 41 | 0.020 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 40 | 0.020 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.019 | |
| protein targeting | GO:0006605 | 143 | 0.019 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.019 | |
| positive regulation of cell cycle process | GO:0090068 | 61 | 0.019 | |
| rhythmic process | GO:0048511 | 174 | 0.019 | |
| female gamete generation | GO:0007292 | 74 | 0.019 | Fly |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.019 | |
| regulation of exit from mitosis | GO:0007096 | 1 | 0.019 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.019 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.019 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.018 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.018 | |
| cell adhesion | GO:0007155 | 329 | 0.018 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.018 | |
| dna replication | GO:0006260 | 52 | 0.018 | |
| dna damage response signal transduction by p53 class mediator | GO:0030330 | 19 | 0.018 | |
| snrna metabolic process | GO:0016073 | 1 | 0.018 | |
| regulation of protein processing | GO:0070613 | 96 | 0.018 | |
| rna processing | GO:0006396 | 105 | 0.018 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.018 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.018 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.018 | |
| mitotic nuclear division | GO:0007067 | 48 | 0.018 | |
| oogenesis | GO:0048477 | 56 | 0.018 | Fly |
| protein catabolic process | GO:0030163 | 221 | 0.018 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.017 | |
| nuclear import | GO:0051170 | 95 | 0.017 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.017 | |
| neuroblast differentiation | GO:0014016 | 2 | 0.017 | |
| establishment or maintenance of cytoskeleton polarity | GO:0030952 | 2 | 0.017 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.017 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.017 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.017 | |
| regulation of protein stability | GO:0031647 | 52 | 0.016 | |
| b cell activation | GO:0042113 | 161 | 0.016 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.016 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.016 | |
| regulation of histone h3 k9 methylation | GO:0051570 | 8 | 0.016 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.016 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.016 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.016 | |
| protein polymerization | GO:0051258 | 57 | 0.016 | |
| negative regulation of histone methylation | GO:0031061 | 10 | 0.016 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.016 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.016 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.015 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.015 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.015 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.015 | |
| protein alkylation | GO:0008213 | 81 | 0.015 | |
| circadian regulation of gene expression | GO:0032922 | 48 | 0.015 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.015 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.015 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.015 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.015 | Fly |
| gland development | GO:0048732 | 330 | 0.015 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 8 | 0.015 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.015 | |
| protein methylation | GO:0006479 | 81 | 0.015 | |
| rna interference | GO:0016246 | 2 | 0.015 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.015 | |
| endomembrane system organization | GO:0010256 | 147 | 0.015 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.015 | |
| aspartate family amino acid metabolic process | GO:0009066 | 10 | 0.015 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.015 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.015 | |
| negative regulation of histone h3 k9 methylation | GO:0051573 | 4 | 0.014 | |
| muscle tissue development | GO:0060537 | 308 | 0.014 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.014 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.014 | |
| motor neuron migration | GO:0097475 | 4 | 0.014 | |
| negative regulation of cell size | GO:0045792 | 3 | 0.014 | |
| regulation of meiotic cell cycle | GO:0051445 | 34 | 0.014 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.014 | |
| erythrocyte differentiation | GO:0030218 | 88 | 0.014 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.014 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.014 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.014 | |
| cell maturation | GO:0048469 | 127 | 0.014 | Fly |
| male meiosis | GO:0007140 | 37 | 0.014 | |
| nuclear transport | GO:0051169 | 139 | 0.014 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.014 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.014 | |
| positive regulation of mitotic cell cycle phase transition | GO:1901992 | 17 | 0.014 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.014 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.013 | |
| purine nucleobase metabolic process | GO:0006144 | 4 | 0.013 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.013 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.013 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.013 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.013 | |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.013 | |
| epithelial cell development | GO:0002064 | 159 | 0.013 | Fly |
| positive regulation of metaphase anaphase transition of cell cycle | GO:1902101 | 2 | 0.013 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.013 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.013 | |
| gtp metabolic process | GO:0046039 | 144 | 0.013 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.013 | |
| male meiosis i | GO:0007141 | 16 | 0.013 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.013 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.013 | |
| spermatid development | GO:0007286 | 108 | 0.013 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.013 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.013 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.013 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.012 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.012 | |
| histone lysine methylation | GO:0034968 | 50 | 0.012 | |
| cell cycle arrest | GO:0007050 | 37 | 0.012 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.012 | |
| regulation of cell motility | GO:2000145 | 236 | 0.012 | |
| ectodermal cell differentiation | GO:0010668 | 3 | 0.012 | |
| regulation of cell migration | GO:0030334 | 219 | 0.012 | |
| immune effector process | GO:0002252 | 321 | 0.012 | |
| regulation of chromosome segregation | GO:0051983 | 21 | 0.012 | |
| regulation of protein binding | GO:0043393 | 60 | 0.012 | |
| response to testosterone | GO:0033574 | 3 | 0.012 | |
| protein ubiquitination | GO:0016567 | 171 | 0.012 | |
| membrane disassembly | GO:0030397 | 1 | 0.012 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.012 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.012 | |
| multicellular organism growth | GO:0035264 | 161 | 0.012 | |
| somatic diversification of immune receptors via germline recombination within a single locus | GO:0002562 | 51 | 0.012 | |
| liver development | GO:0001889 | 66 | 0.012 | |
| cellularization | GO:0007349 | 1 | 0.012 | |
| b cell differentiation | GO:0030183 | 78 | 0.012 | |
| base excision repair | GO:0006284 | 9 | 0.012 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.012 | |
| nuclear dna replication | GO:0033260 | 3 | 0.012 | |
| stem cell fate specification | GO:0048866 | 3 | 0.012 | |
| dna dependent dna replication maintenance of fidelity | GO:0045005 | 3 | 0.012 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.011 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 22 | 0.011 | |
| maintenance of location | GO:0051235 | 89 | 0.011 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.011 | |
| chromosome separation | GO:0051304 | 14 | 0.011 | |
| digestive system development | GO:0055123 | 200 | 0.011 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.011 | |
| response to light stimulus | GO:0009416 | 135 | 0.011 | |
| protein dna complex subunit organization | GO:0071824 | 28 | 0.011 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.011 | |
| localization within membrane | GO:0051668 | 4 | 0.011 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.011 | |
| intracellular protein transport | GO:0006886 | 204 | 0.011 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.011 | |
| zygotic determination of anterior posterior axis embryo | GO:0007354 | 3 | 0.011 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.011 | |
| tube closure | GO:0060606 | 91 | 0.011 | |
| protein localization to membrane | GO:0072657 | 108 | 0.011 | |
| nls bearing protein import into nucleus | GO:0006607 | 2 | 0.011 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.011 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.011 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.011 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.010 | |
| negative regulation of chromatin silencing | GO:0031936 | 1 | 0.010 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.010 | |
| regulation of ran gtpase activity | GO:0032316 | 3 | 0.010 | |
| somatic diversification of immune receptors | GO:0002200 | 53 | 0.010 | |
| stem cell maintenance | GO:0019827 | 130 | 0.010 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.010 | |
| cellular homeostasis | GO:0019725 | 240 | 0.010 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.010 | |
| negative regulation of neuron differentiation | GO:0045665 | 101 | 0.010 | |
| regulation of cell cell adhesion mediated by cadherin | GO:2000047 | 2 | 0.010 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.010 | |
| somatic diversification of immunoglobulins | GO:0016445 | 43 | 0.010 | |
