Mus musculus

0 known processes

Leng8

leukocyte receptor cluster (LRC) member 8

(Aliases: AW049671)

Leng8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.148
myotube differentiationGO:00149021050.108
macromolecule methylationGO:00434141200.098
stem cell maintenanceGO:00198271300.094
dna metabolic processGO:00062593030.073
cellular macromolecule catabolic processGO:00442652060.065
purine containing compound metabolic processGO:00725213110.061
mrna metabolic processGO:0016071840.058
protein methylationGO:0006479810.054
regulation of translationGO:0006417710.054
translationGO:0006412930.054
histone methylationGO:0016571710.054
cellular protein catabolic processGO:00442571550.053
methylationGO:00322591340.053
purine nucleotide metabolic processGO:00061633020.053
monosaccharide metabolic processGO:00059961060.053
aromatic compound catabolic processGO:00194392860.050
purine ribonucleotide metabolic processGO:00091502900.048
membrane fusionGO:0061025380.048
nucleoside phosphate metabolic processGO:00067533380.048
nucleoside metabolic processGO:00091162460.047
regulation of nucleotide metabolic processGO:00061401690.047
membrane organizationGO:00610242450.045
regulation of purine nucleotide catabolic processGO:00331211220.045
positive regulation of nucleoside metabolic processGO:0045979910.044
organelle localizationGO:00516401790.043
regulation of cellular catabolic processGO:00313292420.043
organic cyclic compound catabolic processGO:19013612950.042
lipid homeostasisGO:0055088630.040
microtubule based processGO:00070172360.040
gene silencingGO:0016458380.040
lung developmentGO:00303241640.038
regulation of histone methylationGO:0031060300.038
nucleobase containing small molecule metabolic processGO:00550863520.038
cation transportGO:00068123990.038
sequestering of calcium ionGO:0051208180.037
purine nucleoside catabolic processGO:00061522050.036
positive regulation of histone h3 k27 methylationGO:006108740.036
positive regulation of cyclin dependent protein serine threonine kinase activityGO:004573760.036
striated muscle tissue developmentGO:00147062930.035
stem cell developmentGO:00488642190.035
muscle tissue developmentGO:00605373080.035
positive regulation of protein modification processGO:00314012990.034
respiratory tube developmentGO:00303231670.034
histone lysine methylationGO:0034968500.034
protein alkylationGO:0008213810.034
regulation of reactive oxygen species metabolic processGO:2000377400.034
nucleoside catabolic processGO:00091642060.034
small gtpase mediated signal transductionGO:0007264970.033
carbohydrate derivative catabolic processGO:19011362310.033
cellular nitrogen compound catabolic processGO:00442702800.033
regulation of nucleotide catabolic processGO:00308111220.032
regulation of actin nucleationGO:005112540.032
respiratory system developmentGO:00605411900.032
nucleotide catabolic processGO:00091662170.032
regulation of organelle organizationGO:00330432890.031
leukocyte differentiationGO:00025213420.031
polysaccharide metabolic processGO:0005976390.031
heterocycle catabolic processGO:00467002800.031
regulation of transporter activityGO:0032409570.031
limb morphogenesisGO:00351081490.031
positive regulation of beta amyloid clearanceGO:190022310.031
purine ribonucleotide catabolic processGO:00091542080.030
positive regulation of cellular catabolic processGO:00313311480.029
response to insulinGO:00328681000.029
organic hydroxy compound metabolic processGO:19016152030.029
modification dependent protein catabolic processGO:00199411330.029
regulation of intracellular transportGO:00323861590.029
negative regulation of protein metabolic processGO:00512482820.029
organophosphate catabolic processGO:00464342320.029
cellular response to hormone stimulusGO:00328701500.029
positive regulation of purine nucleotide catabolic processGO:0033123880.028
positive regulation of transferase activityGO:00513471670.028
cellular response to dna damage stimulusGO:00069742070.028
positive regulation of gtpase activityGO:0043547850.028
positive regulation of cell deathGO:00109422240.027
regionalizationGO:00030023370.027
macromolecule catabolic processGO:00090572810.027
regulation of striated muscle cell differentiationGO:0051153810.027
glycosyl compound metabolic processGO:19016572460.027
histone h3 k4 trimethylationGO:008018250.027
regulation of membrane potentialGO:00423911920.026
regulation of cellular response to stressGO:00801351590.026
appendage morphogenesisGO:00351071490.026
epithelial tube morphogenesisGO:00605623030.026
regulation of protein serine threonine kinase activityGO:00719001570.025
proteolysis involved in cellular protein catabolic processGO:00516031470.025
divalent inorganic cation homeostasisGO:00725071380.025
stem cell differentiationGO:00488632680.025
ribonucleoside triphosphate metabolic processGO:00091992200.025
regulation of myotube differentiationGO:0010830620.025
gtp metabolic processGO:00460391440.025
regulation of secretion by cellGO:19035302490.025
carbohydrate metabolic processGO:00059752300.025
regulation of cell cycleGO:00517262810.025
glucose metabolic processGO:0006006920.024
regulation of purine nucleotide metabolic processGO:19005421690.024
gtp catabolic processGO:00061841430.024
gland developmentGO:00487323300.024
guanosine containing compound metabolic processGO:19010681440.024
organonitrogen compound catabolic processGO:19015652640.024
establishment of organelle localizationGO:00516561220.023
cellularizationGO:000734910.023
positive regulation of nucleotide catabolic processGO:0030813880.023
vesicle localizationGO:0051648860.023
regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016310.023
response to peptide hormoneGO:00434341270.023
organic acid biosynthetic processGO:0016053860.023
proteasomal protein catabolic processGO:0010498980.023
sequestering of metal ionGO:0051238190.022
nitrogen compound transportGO:00717052710.022
lipid biosynthetic processGO:00086101790.022
purine nucleoside metabolic processGO:00422782410.022
phosphatidylethanolamine metabolic processGO:004633720.022
cellular ion homeostasisGO:00068731650.022
regulation of neuron differentiationGO:00456642810.022
nucleoside phosphate catabolic processGO:19012922220.022
actin cytoskeleton organizationGO:00300362200.022
regulation of mrna metabolic processGO:1903311430.022
ribonucleotide metabolic processGO:00092592910.022
rhythmic processGO:00485111740.022
lymphocyte differentiationGO:00300982420.022
purine ribonucleoside triphosphate catabolic processGO:00092071990.022
peptidyl amino acid modificationGO:00181933360.021
cellular response to peptideGO:1901653920.021
cellular metal ion homeostasisGO:00068751510.021
positive regulation of gtp catabolic processGO:0033126850.021
rna processingGO:00063961050.021
neural tube closureGO:0001843900.021
regulation of cytoskeleton organizationGO:00514931220.021
negative regulation of cation channel activityGO:200125810.021
developmental maturationGO:00217001930.021
regulation of ion transportGO:00432692150.021
ribonucleotide catabolic processGO:00092612080.021
negative regulation of calcium ion transmembrane transporter activityGO:190102010.021
protein ubiquitinationGO:00165671710.021
multicellular organism growthGO:00352641610.021
phosphatidylethanolamine biosynthetic processGO:000664620.020
hexose metabolic processGO:0019318980.020
cell type specific apoptotic processGO:00972852680.020
regulation of response to drugGO:200102320.020
single fertilizationGO:0007338820.020
carbohydrate biosynthetic processGO:0016051740.020
development of primary sexual characteristicsGO:00451371430.020
organic acid transportGO:00158491010.020
guanosine containing compound catabolic processGO:19010691440.020
carboxylic acid biosynthetic processGO:0046394860.020
wnt signaling pathwayGO:00160551880.020
dna alkylationGO:0006305430.020
regulation of lymphocyte differentiationGO:00456191070.019
cellular response to organonitrogen compoundGO:00714171450.019
male gamete generationGO:00482322850.019
positive regulation of protein phosphorylationGO:00019342420.019
defecationGO:003042110.019
tube formationGO:00351481400.019
regulation of secretionGO:00510462740.019
protein maturationGO:00516041760.019
regulation of cellular ketone metabolic processGO:0010565660.019
ribose phosphate metabolic processGO:00196932910.019
cellular chemical homeostasisGO:00550822150.018
maintenance of locationGO:0051235890.018
cell fate commitmentGO:00451652100.018
multi multicellular organism processGO:00447061090.018
protein localization to organelleGO:00333651850.018
cation transmembrane transportGO:00986552660.018
cellular calcium ion homeostasisGO:00068741190.018
regulation of transferase activityGO:00513382630.018
response to organonitrogen compoundGO:00102432460.018
nucleoside triphosphate catabolic processGO:00091432050.018
purine nucleotide catabolic processGO:00061952110.018
regulation of leukocyte differentiationGO:19021051590.018
positive regulation of hydrolase activityGO:00513451480.018
skeletal system developmentGO:00015013560.018
regulation of ral gtpase activityGO:003231540.018
neuron deathGO:00709971540.018
positive regulation of kinase activityGO:00336741550.017
t cell differentiationGO:00302171740.017
fertilizationGO:00095661270.017
circadian regulation of gene expressionGO:0032922480.017
ribonucleoside catabolic processGO:00424542060.017
regulation of myeloid cell differentiationGO:0045637960.017
glucose homeostasisGO:00425931280.017
positive regulation of programmed cell deathGO:00430682180.017
ras protein signal transductionGO:0007265770.017
actin filament organizationGO:00070151130.017
positive regulation of apoptotic processGO:00430652170.017
sensory perception of mechanical stimulusGO:00509541070.017
organelle fissionGO:00482851700.017
heart contractionGO:0060047930.017
posttranscriptional regulation of gene expressionGO:00106081550.017
cellular response to acid chemicalGO:0071229680.017
exocytosisGO:00068871210.017
ascending thin limb developmentGO:007202120.017
response to acid chemicalGO:00011011110.016
t cell activationGO:00421102890.016
protein processingGO:00164851630.016
embryonic organ morphogenesisGO:00485622760.016
positive regulation of organelle organizationGO:00106381280.016
mitotic cell cycleGO:00002781950.016
positive regulation of nucleotide metabolic processGO:00459811140.016
homeostasis of number of cellsGO:00488722100.016
neuroblast fate determinationGO:000740010.016
protein catabolic processGO:00301632210.016
positive regulation of dna templated transcription elongationGO:003278620.016
regulation of establishment of planar polarityGO:0090175280.016
blood circulationGO:00080151950.016
regulation of vesicle mediated transportGO:00606271390.016
positive regulation of cellular amino acid metabolic processGO:004576430.016
alcohol metabolic processGO:00060661160.016
reactive oxygen species metabolic processGO:0072593840.015
organic anion transportGO:00157111370.015
protein localization to plasma membraneGO:0072659570.015
regulation of hydrolase activityGO:00513362460.015
establishment or maintenance of cell polarityGO:0007163860.015
ribonucleoside metabolic processGO:00091192450.015
regulation of ryanodine sensitive calcium release channel activityGO:0060314100.015
dna modificationGO:0006304500.015
gliogenesisGO:00420631410.015
negative regulation of cellular component organizationGO:00511291940.015
endodermal cell fate specificationGO:000171440.015
protein localization to membraneGO:00726571080.015
calcium ion dependent exocytosisGO:0017156350.015
purine nucleoside triphosphate catabolic processGO:00091462030.015
oxidation reduction processGO:00551143420.015
cellular response to lipidGO:00713961450.015
protein modification by small protein conjugationGO:00324461870.015
regulation of muscle tissue developmentGO:1901861970.015
regulation of reproductive processGO:2000241660.014
regulation of ion transmembrane transportGO:00347651190.014
positive regulation of protein kinase activityGO:00458601440.014
circulatory system processGO:00030131970.014
endoderm developmentGO:0007492450.014
gonad developmentGO:00084061410.014
sensory perceptionGO:00076002450.014
defense response to other organismGO:00985421970.014
synaptic transmissionGO:00072683290.014
ion transmembrane transportGO:00342203610.014
organonitrogen compound biosynthetic processGO:19015661920.014
response to peptideGO:19016521360.014
regulation of cellular response to insulin stimulusGO:1900076300.014
positive regulation of mapk cascadeGO:00434101700.014
monocarboxylic acid metabolic processGO:00327871910.014
actin filament polymerizationGO:0030041440.014
viral gene expressionGO:001908030.014
striated muscle contractionGO:0006941450.014
histone h4 k16 acetylationGO:004398430.014
rho protein signal transductionGO:0007266320.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
small molecule biosynthetic processGO:00442831320.014
cellular amine metabolic processGO:0044106440.014
cellular response to insulin stimulusGO:0032869780.014
negative regulation of organelle organizationGO:0010639900.014
synaptic vesicle transportGO:0048489570.014
mrna processingGO:0006397630.014
modification dependent macromolecule catabolic processGO:00436321330.014
glycosyl compound catabolic processGO:19016582060.014
ovarian follicle developmentGO:0001541400.014
neural precursor cell proliferationGO:00613511210.013
cardiac cell fate specificationGO:006091220.013
myeloid cell differentiationGO:00300992330.013
regulation of calcium ion transmembrane transportGO:1903169200.013
metanephric ascending thin limb developmentGO:007221820.013
intracellular mrna localizationGO:000829840.013
negative regulation of glycoprotein metabolic processGO:190301930.013
establishment of protein localization to membraneGO:0090150540.013
regulation of cellular component sizeGO:00325351210.013
detection of nodal flowGO:000312720.013
regulation of bindingGO:00510981110.013
monocarboxylic acid biosynthetic processGO:0072330610.013
intracellular lipid transportGO:003236530.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
intracellular protein transportGO:00068862040.013
cellular response to fluid shear stressGO:007149840.013
purine ribonucleoside metabolic processGO:00461282410.013
regulation of insulin receptor signaling pathwayGO:0046626210.013
liver developmentGO:0001889660.013
peptide transportGO:00158331330.013
photoreceptor cell morphogenesisGO:000859430.013
regulation of intracellular protein transportGO:0033157820.013
renal system developmentGO:00720012250.013
myeloid cell homeostasisGO:00022621140.013
organic hydroxy compound transportGO:0015850930.013
organophosphate biosynthetic processGO:00904071220.013
sensory perception of soundGO:0007605970.013
plasma membrane organizationGO:0007009900.013
skeletal system morphogenesisGO:00487052030.012
regulation of chromosome organizationGO:0033044830.012
anion transportGO:00068201770.012
regulation of protein transportGO:00512231630.012
dna templated transcription terminationGO:000635340.012
regulation of carbohydrate biosynthetic processGO:0043255400.012
cell adhesionGO:00071553290.012
pharynx developmentGO:006046510.012
nucleotide metabolic processGO:00091173320.012
cellular protein complex assemblyGO:00436231160.012
peptide secretionGO:00027901140.012
germ cell developmentGO:00072811850.012
dephosphorylationGO:00163111290.012
purine ribonucleoside catabolic processGO:00461302050.012
regulation of metal ion transportGO:00109591060.012
regulation of chromatin modificationGO:1903308570.012
cholesterol transportGO:0030301380.012
regulation of cell projection organizationGO:00313442060.012
peptidyl serine modificationGO:0018209830.012
purine containing compound catabolic processGO:00725232130.012
inorganic cation transmembrane transportGO:00986622070.012
negative regulation of cellular amine metabolic processGO:003323910.012
regulation of multi organism processGO:00439001110.011
positive regulation of thymocyte migrationGO:200041220.011
regulation of phospholipase a2 activityGO:003242930.011
forebrain developmentGO:00309003020.011
negative regulation of cell proliferationGO:00082852960.011
anatomical structure homeostasisGO:00602491450.011
metencephalon developmentGO:0022037890.011
regulation of anatomical structure sizeGO:00900661780.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.011
cytosolic calcium ion homeostasisGO:0051480700.011
regulation of protein kinase activityGO:00458592320.011
kidney developmentGO:00018222130.011
chromatin organizationGO:00063252060.011
blastocyst developmentGO:0001824800.011
amine metabolic processGO:0009308450.011
regulation of microtubule based processGO:0032886520.011
regulation of homeostatic processGO:00328441820.011
nucleoside triphosphate metabolic processGO:00091412300.011
cellular ketone metabolic processGO:0042180840.011
carboxylic acid transportGO:00469421000.011
adult behaviorGO:00305341350.011
negative regulation of leukocyte differentiationGO:1902106510.011
chemotaxisGO:00069352470.011
calcium ion transportGO:00068161590.011
negative regulation of translationGO:0017148220.011
positive regulation of secondary heart field cardioblast proliferationGO:007251340.011
regulation of kinase activityGO:00435492490.011
negative regulation of glycoprotein biosynthetic processGO:001056130.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
primary neural tube formationGO:0014020950.011
insulin receptor signaling pathwayGO:0008286490.011
regulation of cell adhesionGO:00301551540.011
peptidyl lysine methylationGO:0018022290.011
negative regulation of cellular protein metabolic processGO:00322692470.011
endocrine system developmentGO:0035270980.011
hindbrain developmentGO:00309021280.011
nucleocytoplasmic transportGO:00069131390.011
regulation of neurotransmitter levelsGO:0001505870.011
inorganic ion transmembrane transportGO:00986602340.011
actin filament based movementGO:0030048230.011
neurotransmitter secretionGO:0007269620.011
regulation of blood circulationGO:1903522930.011
regulation of protein maturationGO:1903317960.011
alpha beta t cell differentiationGO:0046632690.011
negative regulation of triglyceride biosynthetic processGO:001086820.010
nuclear importGO:0051170950.010
response to oxygen radicalGO:0000305160.010
somitogenesisGO:0001756690.010
negative regulation of molecular functionGO:00440922580.010
peptidyl serine phosphorylationGO:0018105740.010
protein modification by small protein conjugation or removalGO:00706472070.010
regulation of neuron deathGO:19012141340.010
regulation of defense response to bacteriumGO:190042430.010
mrna splicing via spliceosomeGO:0000398430.010
regulation of protein localizationGO:00328802310.010
rna splicingGO:0008380540.010
cellular response to peptide hormone stimulusGO:0071375920.010
positive regulation of cellular amine metabolic processGO:003324050.010
circadian rhythmGO:00076231140.010
monosaccharide biosynthetic processGO:0046364440.010
mitochondrion organizationGO:00070051340.010
synaptic vesicle localizationGO:0097479590.010

Leng8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.015
nervous system diseaseDOID:86300.015
disease of anatomical entityDOID:700.015
hematopoietic system diseaseDOID:7400.014
immune system diseaseDOID:291400.014
neurodegenerative diseaseDOID:128900.011
bone remodeling diseaseDOID:008000500.010
bone diseaseDOID:008000100.010
osteopetrosisDOID:1353300.010
osteosclerosisDOID:425400.010
connective tissue diseaseDOID:6500.010
musculoskeletal system diseaseDOID:1700.010