Mus musculus

75 known processes

Numbl

numb-like

(Aliases: nbl)

Numbl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cell developmentGO:00107202370.418
positive regulation of nervous system developmentGO:00519622210.330
regulation of neuron differentiationGO:00456642810.307
Rat
regulation of cellular amino acid metabolic processGO:000652150.242
regulation of cellular amine metabolic processGO:0033238200.176
asymmetric neuroblast divisionGO:005505910.174
Fly
positive regulation of neuron projection developmentGO:0010976790.173
Rat
muscle cell differentiationGO:00426922610.166
Fly
positive regulation of neuron differentiationGO:00456661410.156
Rat
lymphocyte differentiationGO:00300982420.146
positive regulation of cellular amino acid metabolic processGO:004576430.146
organelle localizationGO:00516401790.136
Fly
cellular amino acid metabolic processGO:00065201030.125
positive regulation of cellular amine metabolic processGO:003324050.114
axonogenesisGO:00074092740.114
regulation of cell projection organizationGO:00313442060.101
Rat
anion transportGO:00068201770.095
Worm
myeloid cell homeostasisGO:00022621140.094
Zebrafish
peptidyl amino acid modificationGO:00181933360.094
sulfur compound metabolic processGO:00067901000.093
lateral inhibitionGO:004633110.090
amine metabolic processGO:0009308450.087
cellular amine metabolic processGO:0044106440.086
gliogenesisGO:00420631410.078
Fly
neuroblast division in subventricular zoneGO:002184920.078
synaptic transmissionGO:00072683290.077
chemotaxisGO:00069352470.075
regulation of neuron projection developmentGO:00109751690.075
Rat
negative regulation of molecular functionGO:00440922580.073
skeletal system developmentGO:00015013560.072
cell growthGO:00160491300.072
neuron projection guidanceGO:00974851410.071
regulation of hydrolase activityGO:00513362460.070
dendrite developmentGO:00163581150.070
Rat
positive regulation of cell projection organizationGO:0031346950.067
Rat
positive regulation of protein modification processGO:00314012990.066
protein localization to membraneGO:00726571080.066
Worm
peptidyl tyrosine modificationGO:00182121450.064
neural precursor cell proliferationGO:00613511210.064
nucleobase containing small molecule metabolic processGO:00550863520.063
ion transmembrane transportGO:00342203610.063
cell chemotaxisGO:0060326810.062
regulation of long term synaptic depressionGO:190045230.062
purine ribonucleotide metabolic processGO:00091502900.060
developmental growth involved in morphogenesisGO:00605601380.060
regulation of cellular ketone metabolic processGO:0010565660.060
asymmetric stem cell divisionGO:009872230.059
Fly
transmembrane transportGO:00550854120.059
membrane organizationGO:00610242450.059
Worm
morphogenesis of embryonic epitheliumGO:00163311590.058
cellular ketone metabolic processGO:0042180840.057
negative regulation of protein metabolic processGO:00512482820.054
developmental cell growthGO:0048588840.054
sulfur compound biosynthetic processGO:0044272370.051
regulation of membrane potentialGO:00423911920.051
compound eye developmentGO:004874910.050
regionalizationGO:00030023370.048
regulation of bindingGO:00510981110.048
regulation of vesicle mediated transportGO:00606271390.047
Fly
regulation of apoptotic signaling pathwayGO:20012331970.047
protein modification by small protein conjugation or removalGO:00706472070.047
aromatic compound catabolic processGO:00194392860.047
positive regulation of cell deathGO:00109422240.047
mitotic cell cycle processGO:19030471590.047
regulation of cytoplasmic transportGO:19036491120.046
cell adhesionGO:00071553290.045
learning or memoryGO:00076111480.045
proteoglycan biosynthetic processGO:0030166200.044
myeloid cell differentiationGO:00300992330.043
Zebrafish
forebrain developmentGO:00309003020.042
endomembrane system organizationGO:00102561470.041
transmission of nerve impulseGO:0019226760.041
regulation of mitotic cell cycleGO:00073461260.040
regulation of cellular component biogenesisGO:00440871810.040
mitotic cell cycleGO:00002781950.040
regulation of transmembrane transportGO:00347621280.039
positive regulation of apoptotic processGO:00430652170.039
positive regulation of organelle organizationGO:00106381280.038
cellular lipid metabolic processGO:00442553230.038
purine nucleoside metabolic processGO:00422782410.038
developmental maturationGO:00217001930.038
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.038
Worm
nuclear divisionGO:00002801580.037
locomotory behaviorGO:00076261950.036
regulation of sequence specific dna binding transcription factor activityGO:00510901060.036
negative regulation of cell developmentGO:00107211690.035
stem cell proliferationGO:00720891170.035
leukocyte differentiationGO:00025213420.035
negative regulation of neuron differentiationGO:00456651010.034
monosaccharide metabolic processGO:00059961060.034
histone modificationGO:00165701590.034
negative regulation of immune system processGO:00026832090.034
establishment of protein localization to membraneGO:0090150540.034
Worm
neuron apoptotic processGO:00514021420.034
negative regulation of phosphorus metabolic processGO:00105631840.034
muscle tissue developmentGO:00605373080.034
cognitionGO:00508901490.033
carbohydrate derivative catabolic processGO:19011362310.033
formation of organ boundaryGO:001016010.033
chromatin organizationGO:00063252060.033
organic cyclic compound catabolic processGO:19013612950.033
inorganic cation transmembrane transportGO:00986622070.032
cell fate commitmentGO:00451652100.032
Fly
negative regulation of cellular protein metabolic processGO:00322692470.031
nucleoside phosphate metabolic processGO:00067533380.031
connective tissue developmentGO:00614481790.031
purine nucleotide metabolic processGO:00061633020.031
regulation of cell motilityGO:20001452360.031
intracellular protein transportGO:00068862040.031
Worm
negative regulation of phosphorylationGO:00423261660.030
apoptotic signaling pathwayGO:00971903060.030
inorganic ion transmembrane transportGO:00986602340.030
epithelial tube morphogenesisGO:00605623030.030
respiratory system developmentGO:00605411900.030
Mouse
nucleoside phosphate catabolic processGO:19012922220.030
hematopoietic progenitor cell differentiationGO:00022441430.030
synapse organizationGO:00508081250.030
nucleotide metabolic processGO:00091173320.030
small gtpase mediated signal transductionGO:0007264970.029
stem cell differentiationGO:00488632680.029
negative regulation of phosphate metabolic processGO:00459361840.028
maintenance of locationGO:0051235890.028
regulation of axon extensionGO:0030516430.028
multicellular organismal signalingGO:0035637910.028
ras protein signal transductionGO:0007265770.027
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activityGO:2000311110.027
tube formationGO:00351481400.027
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711330.027
divalent metal ion transportGO:00708381720.027
regulation of neuron apoptotic processGO:00435231220.027
cell divisionGO:00513011200.026
organophosphate catabolic processGO:00464342320.026
regulation of ion transmembrane transporter activityGO:0032412540.026
regulation of postsynaptic membrane potentialGO:0060078480.026
nucleoside triphosphate metabolic processGO:00091412300.026
regulation of synaptic plasticityGO:0048167870.026
neural tube developmentGO:00219151600.026
maintenance of presynaptic active zone structureGO:004879010.026
nucleoside metabolic processGO:00091162460.026
protein modification by small protein conjugationGO:00324461870.026
chromatin modificationGO:00165681870.025
regulation of synaptic growth at neuromuscular junctionGO:000858240.025
single organism cell adhesionGO:00986021560.025
regulation of intracellular transportGO:00323861590.025
negative regulation of protein modification processGO:00314001630.025
regulation of ion transmembrane transportGO:00347651190.025
morphogenesis of a polarized epitheliumGO:0001738370.025
Mouse
regulation of cellular catabolic processGO:00313292420.025
synapse assemblyGO:0007416560.025
ribonucleoside triphosphate catabolic processGO:00092031990.025
negative regulation of cellular component organizationGO:00511291940.024
central nervous system neuron differentiationGO:00219531620.024
cytoplasmic transportGO:00164822340.024
cellular response to lipidGO:00713961450.024
lung developmentGO:00303241640.024
Mouse
gland developmentGO:00487323300.024
axon target recognitionGO:000741240.024
chondroitin sulfate proteoglycan biosynthetic processGO:005065080.024
heterocycle catabolic processGO:00467002800.024
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.024
regulation of auditory receptor cell differentiationGO:004560740.023
purine containing compound metabolic processGO:00725213110.023
regulation of neurotransmitter levelsGO:0001505870.023
cation transportGO:00068123990.023
associative learningGO:0008306610.023
positive regulation of thymocyte migrationGO:200041220.023
membrane depolarizationGO:0051899640.023
response to growth factorGO:00708481980.023
nucleoside triphosphate catabolic processGO:00091432050.023
fat cell differentiationGO:00454441600.023
regulation of cell cycleGO:00517262810.023
response to metal ionGO:0010038470.023
ribonucleoside metabolic processGO:00091192450.023
glial cell migrationGO:000834770.023
Fly
organelle fissionGO:00482851700.023
regulation of peptidyl tyrosine phosphorylationGO:0050730930.023
negative regulation of nervous system developmentGO:00519611560.023
protein palmitoylationGO:0018345140.023
regulation of cell morphogenesis involved in differentiationGO:00107691510.022
Rat
organelle assemblyGO:00709251770.022
cation transmembrane transportGO:00986552660.022
cellular nitrogen compound catabolic processGO:00442702800.021
positive regulation of cellular catabolic processGO:00313311480.021
homeostasis of number of cellsGO:00488722100.021
Zebrafish
axon guidanceGO:00074111410.021
regulation of glutamate receptor signaling pathwayGO:1900449160.021
rho protein signal transductionGO:0007266320.021
extracellular structure organizationGO:00430621480.021
calcium ion transportGO:00068161590.021
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.021
purine nucleoside triphosphate metabolic processGO:00091442260.021
sperm egg recognitionGO:0035036370.021
oocyte axis specificationGO:000730920.021
lipid homeostasisGO:0055088630.021
Mouse
response to radiationGO:00093141650.021
calcium ion transmembrane transportGO:0070588850.021
telencephalon developmentGO:00215371860.020
glial cell differentiationGO:00100011310.020
guanosine containing compound metabolic processGO:19010681440.020
positive regulation of endocytosisGO:0045807420.020
Fly
cartilage developmentGO:00512161400.020
macromolecule catabolic processGO:00090572810.020
neuron migrationGO:00017641220.020
skeletal muscle organ developmentGO:00605381630.020
protein targetingGO:00066051430.020
Worm
regulation of organelle organizationGO:00330432890.020
leukocyte chemotaxisGO:0030595690.020
regulation of actin filament based processGO:0032970990.020
glycosyl compound metabolic processGO:19016572460.020
positive regulation of apoptotic signaling pathwayGO:2001235950.020
cellular response to cytokine stimulusGO:00713451890.020
Human
response to light stimulusGO:00094161350.020
organonitrogen compound catabolic processGO:19015652640.019
protein ubiquitinationGO:00165671710.019
phospholipid metabolic processGO:0006644870.019
posttranscriptional regulation of gene expressionGO:00106081550.019
regulation of transporter activityGO:0032409570.019
sensory organ morphogenesisGO:00905962420.019
nuclear transportGO:00511691390.019
regulation of synaptic transmission glutamatergicGO:0051966190.019
organonitrogen compound biosynthetic processGO:19015661920.019
purine ribonucleoside triphosphate metabolic processGO:00092052200.019
regulation of ion transportGO:00432692150.019
memoryGO:0007613580.019
positive regulation of epithelial cell proliferation involved in wound healingGO:006005420.018
regulation of nucleotide catabolic processGO:00308111220.018
detection of external stimulusGO:0009581610.018
rac protein signal transductionGO:0016601130.018
negative regulation of cell proliferationGO:00082852960.018
positive regulation of programmed cell deathGO:00430682180.018
regulation of protein bindingGO:0043393600.018
intrinsic apoptotic signaling pathwayGO:00971931320.018
neuron projection extensionGO:1990138640.018
peripheral nervous system developmentGO:0007422530.018
peptidyl tyrosine phosphorylationGO:00181081430.018
striated muscle tissue developmentGO:00147062930.018
response to organic cyclic compoundGO:00140701980.018
regulation of protein localizationGO:00328802310.018
negative regulation of cellular amine metabolic processGO:003323910.018
cell type specific apoptotic processGO:00972852680.018
carbohydrate metabolic processGO:00059752300.018
protein localization to synapseGO:0035418110.017
terminal button organizationGO:007255330.017
protein catabolic processGO:00301632210.017
protein targeting to membraneGO:0006612200.017
Worm
positive regulation of growthGO:00459271040.017
leukocyte migrationGO:00509001240.017
ionotropic glutamate receptor signaling pathwayGO:0035235290.017
regulation of asymmetric cell divisionGO:000978640.017
Fly
receptor localization to synapseGO:009712040.017
positive regulation of cytoskeleton organizationGO:0051495490.017
adult locomotory behaviorGO:0008344910.017
response to peptide hormoneGO:00434341270.017
mapk cascadeGO:00001652810.017
positive regulation of purine nucleotide catabolic processGO:0033123880.017
regulation of extent of cell growthGO:0061387520.017
glycosyl compound catabolic processGO:19016582060.017
glycosaminoglycan metabolic processGO:0030203340.017
carbohydrate biosynthetic processGO:0016051740.016
regulation of synaptic vesicle exocytosisGO:2000300110.016
regulation of cellular component sizeGO:00325351210.016
endocytosisGO:00068971680.016
Fly
purine ribonucleoside metabolic processGO:00461282410.016
intracellular mrna localizationGO:000829840.016
nucleoside catabolic processGO:00091642060.016
response to organonitrogen compoundGO:00102432460.016
engulfment of apoptotic cellGO:004365230.016
meiotic nuclear divisionGO:00071261150.016
blood vessel morphogenesisGO:00485142850.016
regulation of eosinophil migrationGO:200041620.016
regulation of thymocyte migrationGO:200041020.015
learningGO:0007612980.015
ribonucleotide catabolic processGO:00092612080.015
cellular protein catabolic processGO:00442571550.015
protein processingGO:00164851630.015
placenta developmentGO:00018901400.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
purine containing compound catabolic processGO:00725232130.015
skeletal system morphogenesisGO:00487052030.015
regulation of cell sizeGO:0008361720.015
negative regulation of protein phosphorylationGO:00019331260.015
regulation of purine nucleotide metabolic processGO:19005421690.015
response to peptideGO:19016521360.015
rna processingGO:00063961050.015
positive regulation of eosinophil migrationGO:200041820.015
positive regulation of gtp catabolic processGO:0033126850.015
positive regulation of t cell activationGO:00508701010.015
regulation of synaptic vesicle transportGO:1902803130.015
regulation of endopeptidase activityGO:0052548890.015
oxidation reduction processGO:00551143420.015
negative regulation of lyase activityGO:005135010.015
ribonucleotide metabolic processGO:00092592910.015
central nervous system neuron developmentGO:0021954670.015
apoptotic mitochondrial changesGO:0008637480.015
cellular response to growth factor stimulusGO:00713631970.015
somitogenesisGO:0001756690.015
regulation of fat cell differentiationGO:0045598810.015
adult behaviorGO:00305341350.015
aminoglycan metabolic processGO:0006022340.015
purine ribonucleoside triphosphate catabolic processGO:00092071990.015
carbohydrate derivative biosynthetic processGO:19011371830.014
organic acid transportGO:00158491010.014
multi organism behaviorGO:0051705620.014
regulation of cell cycle processGO:00105641600.014
extracellular matrix organizationGO:00301981470.014
chondroitin sulfate proteoglycan metabolic processGO:0050654200.014
ribonucleoside catabolic processGO:00424542060.014
regulation of transferase activityGO:00513382630.014
organic hydroxy compound metabolic processGO:19016152030.014
embryonic epithelial tube formationGO:00018381300.014
dendritic spine developmentGO:0060996300.014
circadian regulation of gene expressionGO:0032922480.014
regulation of exocytosisGO:0017157610.014
positive regulation of glutamate receptor signaling pathwayGO:190045130.014
thymocyte migrationGO:007267920.014
mrna metabolic processGO:0016071840.014
positive regulation of nucleoside metabolic processGO:0045979910.014
establishment of protein localization to organelleGO:00725941180.014
renal system developmentGO:00720012250.014
Fly
guanosine containing compound catabolic processGO:19010691440.014
cellular response to hormone stimulusGO:00328701500.014
positive regulation of leukocyte differentiationGO:1902107860.014
visual behaviorGO:0007632450.014
actin cytoskeleton organizationGO:00300362200.014
regulation of dendritic spine developmentGO:0060998220.014
translationGO:0006412930.014
regulation of nucleoside metabolic processGO:00091181300.014
segmentationGO:0035282930.014
purine ribonucleotide catabolic processGO:00091542080.014
glycoprotein biosynthetic processGO:0009101890.014
regulation of translationGO:0006417710.014
protein autophosphorylationGO:0046777610.014
regulation of cell activationGO:00508652890.014
morphogenesis of a branching epitheliumGO:00611381930.014
regulation of neural precursor cell proliferationGO:2000177700.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.013
response to inactivityGO:001485440.013
regulation of cytokine productionGO:00018172660.013
lipid biosynthetic processGO:00086101790.013
positive regulation of cell cycleGO:0045787920.013
t cell differentiation in thymusGO:0033077770.013
ensheathment of neuronsGO:0007272760.013
purine nucleoside catabolic processGO:00061522050.013
protein localization to plasma membraneGO:0072659570.013
sensory perception of chemical stimulusGO:0007606510.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
positive regulation of cellular component biogenesisGO:0044089940.013
regulation of organ morphogenesisGO:20000271440.013
Mouse
neuromuscular processGO:0050905990.013
microtubule based processGO:00070172360.013
protein maturationGO:00516041760.013
long term synaptic potentiationGO:0060291250.013
neuron deathGO:00709971540.013
lymphocyte apoptotic processGO:0070227540.013
neutrophil migrationGO:1990266370.013
covalent chromatin modificationGO:00165691630.013
regulation of reactive oxygen species metabolic processGO:2000377400.013
cerebral cortex radially oriented cell migrationGO:0021799310.013
primitive erythrocyte differentiationGO:006031930.013
Zebrafish
regulation of receptor activityGO:0010469410.013
synaptic transmission glutamatergicGO:0035249360.013
respiratory tube developmentGO:00303231670.013
Mouse
negative regulation of cellular response to growth factor stimulusGO:0090288460.013
fatty acid metabolic processGO:00066311210.013
dendritic spine maintenanceGO:009706240.013
sodium ion transmembrane transportGO:0035725490.013
gonad developmentGO:00084061410.013
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.013
metencephalon developmentGO:0022037890.012
ribose phosphate metabolic processGO:00196932910.012
inflammatory responseGO:00069542440.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
divalent inorganic cation transportGO:00725111780.012
cellular response to inorganic substanceGO:0071241370.012
positive regulation of protein phosphorylationGO:00019342420.012
regulation of cell divisionGO:0051302760.012
Fly
negative regulation of intracellular signal transductionGO:19025321670.012
cellular response to organonitrogen compoundGO:00714171450.012
proteoglycan metabolic processGO:0006029380.012
regulation of synapse structural plasticityGO:005182340.012
gene silencingGO:0016458380.012
neurotransmitter secretionGO:0007269620.012
negative regulation of myeloid cell differentiationGO:0045638380.012
regulation of cell growthGO:0001558910.012
establishment of organelle localizationGO:00516561220.012
regulation of homeostatic processGO:00328441820.012
actomyosin structure organizationGO:0031032560.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
synaptic vesicle membrane organizationGO:004849910.012
multicellular organismal response to stressGO:0033555620.012
t cell activationGO:00421102890.012
mesoderm developmentGO:00074981000.012
pallium developmentGO:00215431200.012
negative regulation of lymphocyte activationGO:0051250910.012
telencephalon cell migrationGO:0022029550.012
positive regulation of membrane protein ectodomain proteolysisGO:005104430.012
camera type eye developmentGO:00430102660.012
maternal determination of anterior posterior axis embryoGO:000835820.012
gtp catabolic processGO:00061841430.012
positive regulation of nucleotide catabolic processGO:0030813880.011
myeloid leukocyte migrationGO:0097529570.011
lipid localizationGO:00108761260.011
Worm
methylationGO:00322591340.011
regulation of anatomical structure sizeGO:00900661780.011
regulation of cellular response to stressGO:00801351590.011
negative regulation of cell activationGO:00508661110.011
positive regulation of glutamate secretionGO:001404920.011
axon ensheathmentGO:0008366760.011
neurotransmitter transportGO:0006836760.011
cell cell junction organizationGO:0045216720.011
cell proliferation in forebrainGO:0021846300.011
rna splicingGO:0008380540.011
regulation of secretion by cellGO:19035302490.011
immune effector processGO:00022523210.011
regulation of proteolysisGO:00301621640.011
actin polymerization or depolymerizationGO:0008154540.011
regulation of protein kinase activityGO:00458592320.011
nucleotide catabolic processGO:00091662170.011
regulation of protein localization to nucleusGO:1900180600.011
regulation of establishment of protein localizationGO:00702011810.011
single fertilizationGO:0007338820.011
regulation of leukocyte differentiationGO:19021051590.011
oocyte constructionGO:000730820.011
neuron maturationGO:0042551290.011
postsynaptic membrane organizationGO:0001941180.011
cellular component assembly involved in morphogenesisGO:00109271390.011
ubiquitin dependent protein catabolic processGO:00065111290.011
establishment or maintenance of cell polarityGO:0007163860.011
negative regulation of mechanoreceptor differentiationGO:004563230.011
sterol metabolic processGO:0016125580.011
regulation of cell migrationGO:00303342190.011
positive regulation of long term neuronal synaptic plasticityGO:004817030.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
purine nucleotide catabolic processGO:00061952110.011
myelination in peripheral nervous systemGO:0022011190.011
regulation of t cell activationGO:00508631700.011
reactive oxygen species metabolic processGO:0072593840.011
purine ribonucleoside catabolic processGO:00461302050.011
regulation of intracellular protein transportGO:0033157820.011
regulation of protein catabolic processGO:00421761080.010
cellular response to dna damage stimulusGO:00069742070.010
sterol homeostasisGO:0055092450.010
Mouse
prevention of polyspermyGO:006046840.010
mitochondrion organizationGO:00070051340.010
rna interferenceGO:001624620.010
hindbrain developmentGO:00309021280.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
nephron epithelium morphogenesisGO:0072088680.010
regulation of circadian rhythmGO:0042752580.010
negative regulation of transferase activityGO:0051348850.010
dorsal ventral axon guidanceGO:003356330.010
cardiac muscle tissue developmentGO:00487381300.010
actin filament organizationGO:00070151130.010
spinal cord motor neuron cell fate specificationGO:0021520130.010
regulation of inositol phosphate biosynthetic processGO:001091930.010
t cell differentiationGO:00302171740.010
ventricular system developmentGO:0021591270.010
multi multicellular organism processGO:00447061090.010

Numbl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.035
musculoskeletal system diseaseDOID:1700.033
disease of anatomical entityDOID:700.033
bone development diseaseDOID:008000600.023
connective tissue diseaseDOID:6500.023
bone diseaseDOID:008000100.023
acquired metabolic diseaseDOID:006015800.012