| protein modification by small protein conjugation | GO:0032446 | 187 | 0.173 | |
| intracellular protein transport | GO:0006886 | 204 | 0.111 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.108 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.092 | |
| protein localization to organelle | GO:0033365 | 185 | 0.085 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.082 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.063 | |
| protein targeting | GO:0006605 | 143 | 0.061 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.060 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.056 | |
| endocytosis | GO:0006897 | 168 | 0.052 | |
| protein ubiquitination | GO:0016567 | 171 | 0.050 | |
| misfolded protein transport | GO:0070843 | 1 | 0.050 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.049 | |
| membrane organization | GO:0061024 | 245 | 0.049 | Human |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.047 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.045 | |
| protein catabolic process | GO:0030163 | 221 | 0.043 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.043 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.042 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.042 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.041 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.041 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.041 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.041 | |
| regulation of protein localization | GO:0032880 | 231 | 0.040 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.040 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.040 | |
| synaptic transmission | GO:0007268 | 329 | 0.038 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.038 | |
| male gamete generation | GO:0048232 | 285 | 0.038 | |
| mapk cascade | GO:0000165 | 281 | 0.038 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.037 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.035 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.035 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.033 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.032 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.032 | |
| cognition | GO:0050890 | 149 | 0.032 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.032 | |
| spermatogenesis | GO:0007283 | 284 | 0.031 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.031 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.031 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.030 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.030 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.030 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.030 | |
| regulation of protein transport | GO:0051223 | 163 | 0.030 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.030 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.029 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.029 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.029 | |
| microtubule based process | GO:0007017 | 236 | 0.028 | Human |
| nuclear division | GO:0000280 | 158 | 0.027 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.027 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.027 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.027 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.027 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.027 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.027 | |
| protein import | GO:0017038 | 101 | 0.026 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.026 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.025 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.025 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.025 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.025 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.025 | |
| action potential | GO:0001508 | 78 | 0.025 | |
| multicellular organism growth | GO:0035264 | 161 | 0.025 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.025 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.025 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.024 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.024 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.024 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.024 | |
| histone modification | GO:0016570 | 159 | 0.023 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.023 | |
| nuclear transport | GO:0051169 | 139 | 0.023 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.022 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.022 | |
| response to peptide hormone | GO:0043434 | 127 | 0.022 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.022 | |
| gland development | GO:0048732 | 330 | 0.022 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.021 | Human |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.021 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.021 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.021 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.021 | |
| dendrite development | GO:0016358 | 115 | 0.021 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.021 | |
| organelle fission | GO:0048285 | 170 | 0.020 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.020 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.020 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.020 | |
| adult behavior | GO:0030534 | 135 | 0.020 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.020 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.020 | |
| myosin filament organization | GO:0031033 | 3 | 0.020 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.020 | |
| protein localization to membrane | GO:0072657 | 108 | 0.019 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.019 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.019 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.019 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.019 | |
| single organism nuclear import | GO:1902593 | 95 | 0.019 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.019 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.019 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.019 | |
| fat cell differentiation | GO:0045444 | 160 | 0.019 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.019 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.018 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.018 | |
| localization within membrane | GO:0051668 | 4 | 0.018 | |
| striated muscle myosin thick filament assembly | GO:0071688 | 1 | 0.018 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.018 | |
| protein import into nucleus | GO:0006606 | 95 | 0.018 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.018 | |
| amine metabolic process | GO:0009308 | 45 | 0.018 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.018 | |
| synapsis | GO:0007129 | 34 | 0.018 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.018 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.018 | |
| camera type eye development | GO:0043010 | 266 | 0.018 | |
| cytokine production | GO:0001816 | 319 | 0.018 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.018 | |
| regionalization | GO:0003002 | 337 | 0.017 | |
| regulation of secretion | GO:0051046 | 274 | 0.017 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.017 | |
| fertilization | GO:0009566 | 127 | 0.017 | |
| oocyte axis specification | GO:0007309 | 2 | 0.017 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.017 | |
| nuclear import | GO:0051170 | 95 | 0.017 | |
| vesicle organization | GO:0016050 | 60 | 0.016 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.016 | |
| organelle assembly | GO:0070925 | 177 | 0.016 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.016 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.016 | |
| transmembrane transport | GO:0055085 | 412 | 0.016 | |
| chromatin organization | GO:0006325 | 206 | 0.016 | |
| rna processing | GO:0006396 | 105 | 0.016 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.016 | |
| learning or memory | GO:0007611 | 148 | 0.016 | |
| neural tube development | GO:0021915 | 160 | 0.016 | |
| cell division | GO:0051301 | 120 | 0.016 | |
| dna recombination | GO:0006310 | 92 | 0.016 | |
| synapse organization | GO:0050808 | 125 | 0.016 | |
| gtp metabolic process | GO:0046039 | 144 | 0.016 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.016 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.016 | |
| locomotory behavior | GO:0007626 | 195 | 0.015 | |
| amide transport | GO:0042886 | 138 | 0.015 | |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.015 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.015 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.015 | |
| tube formation | GO:0035148 | 140 | 0.015 | |
| regulation of protein import into nucleus | GO:0042306 | 52 | 0.015 | |
| response to radiation | GO:0009314 | 165 | 0.015 | |
| response to peptide | GO:1901652 | 136 | 0.015 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.015 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.015 | |
| dna metabolic process | GO:0006259 | 303 | 0.015 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.015 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.015 | |
| methylation | GO:0032259 | 134 | 0.015 | |
| neuronal action potential | GO:0019228 | 54 | 0.015 | |
| stem cell maintenance | GO:0019827 | 130 | 0.014 | |
| spermatid differentiation | GO:0048515 | 115 | 0.014 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.014 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.014 | |
| cell adhesion | GO:0007155 | 329 | 0.014 | |
| muscle tissue development | GO:0060537 | 308 | 0.014 | |
| neural tube closure | GO:0001843 | 90 | 0.014 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.014 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.014 | |
| male genitalia morphogenesis | GO:0048808 | 4 | 0.014 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.014 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.014 | |
| stem cell development | GO:0048864 | 219 | 0.014 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.014 | |
| chromosome organization involved in meiosis | GO:0070192 | 39 | 0.014 | |
| learning | GO:0007612 | 98 | 0.014 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.014 | |
| histone h2a ubiquitination | GO:0033522 | 3 | 0.014 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.014 | |
| insulin receptor signaling pathway | GO:0008286 | 49 | 0.014 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.014 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.014 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.014 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.014 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.013 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.013 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.013 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.013 | |
| chromatin modification | GO:0016568 | 187 | 0.013 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.013 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.013 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.013 | |
| single fertilization | GO:0007338 | 82 | 0.013 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.013 | |
| lipid localization | GO:0010876 | 126 | 0.013 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.013 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.013 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.013 | |
| blastocyst development | GO:0001824 | 80 | 0.013 | |
| male anatomical structure morphogenesis | GO:0090598 | 4 | 0.013 | |
| lateral inhibition | GO:0046331 | 1 | 0.013 | |
| regulation of cell motility | GO:2000145 | 236 | 0.013 | |
| male meiosis | GO:0007140 | 37 | 0.013 | |
| regulation of translation | GO:0006417 | 71 | 0.013 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.013 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.013 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.013 | |
| rhythmic process | GO:0048511 | 174 | 0.013 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.012 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.012 | |
| oxidation reduction process | GO:0055114 | 342 | 0.012 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.012 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.012 | |
| adult locomotory behavior | GO:0008344 | 91 | 0.012 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.012 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.012 | |
| digestive system development | GO:0055123 | 200 | 0.012 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.012 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.012 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.012 | |
| chemotaxis | GO:0006935 | 247 | 0.012 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.012 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.012 | |
| lipid modification | GO:0030258 | 65 | 0.012 | |
| germ cell development | GO:0007281 | 185 | 0.012 | |
| regulation of histone modification | GO:0031056 | 56 | 0.012 | |
| p38mapk cascade | GO:0038066 | 4 | 0.012 | |
| negative regulation of synaptic transmission glutamatergic | GO:0051967 | 4 | 0.012 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.012 | |
| skeletal muscle organ development | GO:0060538 | 163 | 0.012 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.012 | |
| cellular response to peptide | GO:1901653 | 92 | 0.012 | |
| primary neural tube formation | GO:0014020 | 95 | 0.012 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.012 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.012 | |
| memory | GO:0007613 | 58 | 0.012 | |
| defense response to other organism | GO:0098542 | 197 | 0.012 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.011 | |
| forebrain development | GO:0030900 | 302 | 0.011 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.011 | |
| regulation of defense response | GO:0031347 | 233 | 0.011 | |
| striated muscle cell development | GO:0055002 | 125 | 0.011 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.011 | |
| mrna metabolic process | GO:0016071 | 84 | 0.011 | |
| cell maturation | GO:0048469 | 127 | 0.011 | |
| response to light stimulus | GO:0009416 | 135 | 0.011 | |
| response to sterol | GO:0036314 | 4 | 0.011 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.011 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.011 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.011 | |
| telencephalon development | GO:0021537 | 186 | 0.011 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.011 | |
| muscle cell development | GO:0055001 | 133 | 0.011 | |
| skeletal system development | GO:0001501 | 356 | 0.011 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.011 | |
| blastocyst formation | GO:0001825 | 33 | 0.011 | |
| cellular homeostasis | GO:0019725 | 240 | 0.011 | Human |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.011 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.011 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.011 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.011 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.011 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.011 | |
| peptide transport | GO:0015833 | 133 | 0.011 | |
| secretory granule organization | GO:0033363 | 20 | 0.011 | |
| cellularization | GO:0007349 | 1 | 0.011 | |
| lipoprotein biosynthetic process | GO:0042158 | 33 | 0.011 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.011 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.011 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.011 | |
| regulation of protein stability | GO:0031647 | 52 | 0.011 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.011 | |
| regulation of nuclear division | GO:0051783 | 56 | 0.011 | |
| oocyte construction | GO:0007308 | 2 | 0.011 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.011 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.011 | |
| protein glycosylation | GO:0006486 | 55 | 0.010 | |
| positive regulation of potassium ion transport | GO:0043268 | 3 | 0.010 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.010 | |
| cell growth | GO:0016049 | 130 | 0.010 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.010 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.010 | |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.010 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.010 | |
| intracellular mrna localization | GO:0008298 | 4 | 0.010 | |
| protein polymerization | GO:0051258 | 57 | 0.010 | |
| maintenance of location | GO:0051235 | 89 | 0.010 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.010 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.010 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.010 | |
| positive regulation of growth | GO:0045927 | 104 | 0.010 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.010 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.010 | |
| response to insulin | GO:0032868 | 100 | 0.010 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.010 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.010 | |
| regulation of cell activation | GO:0050865 | 289 | 0.010 | |
| neural tube formation | GO:0001841 | 108 | 0.010 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.010 | |
| pole plasm assembly | GO:0007315 | 2 | 0.010 | |
| negative regulation of tor signaling | GO:0032007 | 13 | 0.010 | |
| gonad development | GO:0008406 | 141 | 0.010 | |
| regulation of ion transport | GO:0043269 | 215 | 0.010 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.010 | |
