IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Fam154b

family with sequence similarity 154, member B

(Aliases: 1700129I04Rik,D030069K18)

Entrez: 330577
Ensembl: ENSMUSG00000038570
UniProtKB: Q8BQB6

Process Predictions
Disease Predictions

Fam154b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cation transport	GO:0006812	399	0.037
male gamete generation	GO:0048232	285	0.035
microtubule based movement	GO:0007018	84	0.033
microtubule based process	GO:0007017	236	0.031
cellular amino acid metabolic process	GO:0006520	103	0.028
nucleoside phosphate metabolic process	GO:0006753	338	0.028
regulation of cellular amino acid metabolic process	GO:0006521	5	0.027
regulation of cellular amine metabolic process	GO:0033238	20	0.027
cellular amine metabolic process	GO:0044106	44	0.026
macromolecule catabolic process	GO:0009057	281	0.025
transmembrane transport	GO:0055085	412	0.025
spermatogenesis	GO:0007283	284	0.023
fertilization	GO:0009566	127	0.023
cation transmembrane transport	GO:0098655	266	0.023
positive regulation of cell development	GO:0010720	237	0.022
ras protein signal transduction	GO:0007265	77	0.022
negative regulation of cellular protein metabolic process	GO:0032269	247	0.022
hematopoietic progenitor cell differentiation	GO:0002244	143	0.021
regulation of cellular ketone metabolic process	GO:0010565	66	0.021
inorganic cation transmembrane transport	GO:0098662	207	0.021
negative regulation of cell proliferation	GO:0008285	296	0.021
homeostasis of number of cells	GO:0048872	210	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.020
positive regulation of cellular amine metabolic process	GO:0033240	5	0.020
ribose phosphate metabolic process	GO:0019693	291	0.020
ion transmembrane transport	GO:0034220	361	0.020
nucleobase containing small molecule metabolic process	GO:0055086	352	0.020
amine metabolic process	GO:0009308	45	0.020
cilium morphogenesis	GO:0060271	102	0.020
negative regulation of molecular function	GO:0044092	258	0.020
negative regulation of protein metabolic process	GO:0051248	282	0.019
ribonucleotide metabolic process	GO:0009259	291	0.019
response to organonitrogen compound	GO:0010243	246	0.019
cilium assembly	GO:0042384	81	0.019
cellular homeostasis	GO:0019725	240	0.019
nucleotide metabolic process	GO:0009117	332	0.018
heterocycle catabolic process	GO:0046700	280	0.018
aromatic compound catabolic process	GO:0019439	286	0.018
regulation of cell adhesion	GO:0030155	154	0.018
cellular ketone metabolic process	GO:0042180	84	0.018
organelle fission	GO:0048285	170	0.017
inorganic ion transmembrane transport	GO:0098660	234	0.017
purine containing compound metabolic process	GO:0072521	311	0.017
protein catabolic process	GO:0030163	221	0.017
nuclear division	GO:0000280	158	0.017
cellular nitrogen compound catabolic process	GO:0044270	280	0.017
regulation of cell activation	GO:0050865	289	0.017
nucleoside phosphate catabolic process	GO:1901292	222	0.016
carbohydrate derivative catabolic process	GO:1901136	231	0.016
cellular component assembly involved in morphogenesis	GO:0010927	139	0.016
positive regulation of protein modification process	GO:0031401	299	0.016
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.016
purine nucleotide metabolic process	GO:0006163	302	0.016
purine nucleotide catabolic process	GO:0006195	211	0.016
sensory perception	GO:0007600	245	0.015
leukocyte differentiation	GO:0002521	342	0.015
nucleoside metabolic process	GO:0009116	246	0.015
organelle localization	GO:0051640	179	0.015
posttranscriptional regulation of gene expression	GO:0010608	155	0.015
organic cyclic compound catabolic process	GO:1901361	295	0.015
camera type eye development	GO:0043010	266	0.015
purine ribonucleotide metabolic process	GO:0009150	290	0.015
purine ribonucleoside metabolic process	GO:0046128	241	0.015
regulation of membrane potential	GO:0042391	192	0.015
regulation of lymphocyte activation	GO:0051249	240	0.015
spermatid differentiation	GO:0048515	115	0.015
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.015
regulation of protein localization	GO:0032880	231	0.014
membrane organization	GO:0061024	245	0.014
nucleoside triphosphate metabolic process	GO:0009141	230	0.014
cellular response to organonitrogen compound	GO:0071417	145	0.014
protein modification by small protein conjugation or removal	GO:0070647	207	0.014
g protein coupled receptor signaling pathway	GO:0007186	243	0.014
regulation of system process	GO:0044057	200	0.014
regulation of nucleotide metabolic process	GO:0006140	169	0.014
organelle assembly	GO:0070925	177	0.014
regulation of cell projection organization	GO:0031344	206	0.014
regulation of cellular catabolic process	GO:0031329	242	0.014
positive regulation of nervous system development	GO:0051962	221	0.014
smoothened signaling pathway	GO:0007224	105	0.014
cell type specific apoptotic process	GO:0097285	268	0.014
cytokine production	GO:0001816	319	0.014
adult behavior	GO:0030534	135	0.014
synaptic transmission	GO:0007268	329	0.013
small gtpase mediated signal transduction	GO:0007264	97	0.013
response to organic cyclic compound	GO:0014070	198	0.013
cilium movement	GO:0003341	28	0.013
regulation of organelle organization	GO:0033043	289	0.013
cellular chemical homeostasis	GO:0055082	215	0.013
ribonucleoside metabolic process	GO:0009119	245	0.013
regulation of cell cycle	GO:0051726	281	0.013
regulation of hydrolase activity	GO:0051336	246	0.013
negative regulation of protein modification process	GO:0031400	163	0.013
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.013
rho protein signal transduction	GO:0007266	32	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.013
regulation of neuron death	GO:1901214	134	0.013
organophosphate catabolic process	GO:0046434	232	0.013
cellular response to lipid	GO:0071396	145	0.013
protein ubiquitination	GO:0016567	171	0.013
inflammatory response	GO:0006954	244	0.013
spermatid development	GO:0007286	108	0.013
regulation of cellular component biogenesis	GO:0044087	181	0.013
t cell activation	GO:0042110	289	0.013
forebrain development	GO:0030900	302	0.012
cellular ion homeostasis	GO:0006873	165	0.012
germ cell development	GO:0007281	185	0.012
regulation of proteolysis	GO:0030162	164	0.012
divalent inorganic cation homeostasis	GO:0072507	138	0.012
apoptotic signaling pathway	GO:0097190	306	0.012
response to radiation	GO:0009314	165	0.012
regulation of apoptotic signaling pathway	GO:2001233	197	0.012
cellular macromolecule catabolic process	GO:0044265	206	0.012
negative regulation of cellular component organization	GO:0051129	194	0.012
nitrogen compound transport	GO:0071705	271	0.012
cell adhesion	GO:0007155	329	0.012
purine nucleoside metabolic process	GO:0042278	241	0.012
sequestering of calcium ion	GO:0051208	18	0.012
sensory organ morphogenesis	GO:0090596	242	0.012
regulation of cell cycle process	GO:0010564	160	0.012
carbohydrate derivative biosynthetic process	GO:1901137	183	0.012
purine ribonucleotide catabolic process	GO:0009154	208	0.012
tissue homeostasis	GO:0001894	115	0.012
regulation of transferase activity	GO:0051338	263	0.012
positive regulation of transferase activity	GO:0051347	167	0.012
regulation of purine nucleotide metabolic process	GO:1900542	169	0.012
glycosyl compound metabolic process	GO:1901657	246	0.012
negative regulation of protein phosphorylation	GO:0001933	126	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.012
calcium ion transport	GO:0006816	159	0.012
protein modification by small protein conjugation	GO:0032446	187	0.012
positive regulation of neuron differentiation	GO:0045666	141	0.012
maintenance of location	GO:0051235	89	0.011
learning or memory	GO:0007611	148	0.011
positive regulation of protein phosphorylation	GO:0001934	242	0.011
cellular protein complex assembly	GO:0043623	116	0.011
regulation of kinase activity	GO:0043549	249	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.011
organonitrogen compound catabolic process	GO:1901565	264	0.011
anion transport	GO:0006820	177	0.011
ribonucleoside catabolic process	GO:0042454	206	0.011
endomembrane system organization	GO:0010256	147	0.011
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.011
ribonucleotide catabolic process	GO:0009261	208	0.011
protein localization to nucleus	GO:0034504	121	0.011
dephosphorylation	GO:0016311	129	0.011
peptidyl amino acid modification	GO:0018193	336	0.011
neural precursor cell proliferation	GO:0061351	121	0.011
regulation of cell substrate adhesion	GO:0010810	73	0.011
multicellular organism growth	GO:0035264	161	0.011
response to light stimulus	GO:0009416	135	0.011
lymphocyte differentiation	GO:0030098	242	0.011
metal ion homeostasis	GO:0055065	189	0.011
regulation of ion transport	GO:0043269	215	0.011
male meiosis	GO:0007140	37	0.011
positive regulation of hydrolase activity	GO:0051345	148	0.011
regulation of vesicle mediated transport	GO:0060627	139	0.011
reactive oxygen species biosynthetic process	GO:1903409	8	0.011
single organism cell adhesion	GO:0098602	156	0.011
locomotory behavior	GO:0007626	195	0.011
regulation of ion transmembrane transport	GO:0034765	119	0.011
protein targeting	GO:0006605	143	0.011
single fertilization	GO:0007338	82	0.011
regulation of cell motility	GO:2000145	236	0.011
protein maturation	GO:0051604	176	0.011
divalent metal ion transport	GO:0070838	172	0.011
positive regulation of cellular catabolic process	GO:0031331	148	0.011
meiotic nuclear division	GO:0007126	115	0.011
oocyte construction	GO:0007308	2	0.011
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
organonitrogen compound biosynthetic process	GO:1901566	192	0.011
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.011
intracellular mrna localization	GO:0008298	4	0.010
oocyte axis specification	GO:0007309	2	0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.010
regulation of protein catabolic process	GO:0042176	108	0.010
proteasomal protein catabolic process	GO:0010498	98	0.010
purine containing compound catabolic process	GO:0072523	213	0.010
epithelial cell proliferation	GO:0050673	174	0.010
negative regulation of phosphorylation	GO:0042326	166	0.010
cell substrate adhesion	GO:0031589	130	0.010
chromatin organization	GO:0006325	206	0.010
negative regulation of phosphate metabolic process	GO:0045936	184	0.010
calcium ion transmembrane transport	GO:0070588	85	0.010
mitotic cell cycle process	GO:1903047	159	0.010
nucleotide catabolic process	GO:0009166	217	0.010
mitotic cell cycle	GO:0000278	195	0.010
calcium ion homeostasis	GO:0055074	127	0.010
protein localization to organelle	GO:0033365	185	0.010
cation homeostasis	GO:0055080	212	0.010
regulation of leukocyte differentiation	GO:1902105	159	0.010
modification dependent macromolecule catabolic process	GO:0043632	133	0.010
male sex differentiation	GO:0046661	109	0.010
cognition	GO:0050890	149	0.010

Fam154b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.022
nervous system disease	DOID:863	0.022
eye and adnexa disease	DOID:1492	0.019
sensory system disease	DOID:0050155	0.019
primary ciliary dyskinesia	DOID:9562	0.018
eye disease	DOID:5614	0.012
musculoskeletal system disease	DOID:17	0.011
retinal degeneration	DOID:8466	0.011
retinal disease	DOID:5679	0.011
central nervous system disease	DOID:331	0.011
disease of cellular proliferation	DOID:14566	0.010

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