Mus musculus

0 known processes

Mapk4

mitogen-activated protein kinase 4

(Aliases: A330097D03Rik,Erk3,p63Mapk,Prkm4)

Mapk4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mapk cascadeGO:00001652810.110
Mouse
regulation of membrane potentialGO:00423911920.087
amine metabolic processGO:0009308450.081
regulation of kinase activityGO:00435492490.068
cellular amino acid metabolic processGO:00065201030.066
regulation of cellular ketone metabolic processGO:0010565660.061
regulation of cellular amino acid metabolic processGO:000652150.060
positive regulation of protein modification processGO:00314012990.059
regulation of cellular amine metabolic processGO:0033238200.056
positive regulation of protein phosphorylationGO:00019342420.056
male gamete generationGO:00482322850.056
protein modification by small protein conjugation or removalGO:00706472070.051
regulation of organelle organizationGO:00330432890.051
connective tissue developmentGO:00614481790.050
positive regulation of cellular amino acid metabolic processGO:004576430.049
transmission of nerve impulseGO:0019226760.048
regulation of cell projection organizationGO:00313442060.047
negative regulation of molecular functionGO:00440922580.046
multicellular organismal signalingGO:0035637910.046
regulation of secretion by cellGO:19035302490.046
cation transportGO:00068123990.046
regulation of mapk cascadeGO:00434082480.045
macromolecule catabolic processGO:00090572810.044
action potentialGO:0001508780.044
muscle tissue developmentGO:00605373080.043
cellular macromolecule catabolic processGO:00442652060.043
ras protein signal transductionGO:0007265770.042
skin developmentGO:00435882200.040
cellular protein catabolic processGO:00442571550.040
regulation of protein kinase activityGO:00458592320.039
spermatogenesisGO:00072832840.038
apoptotic signaling pathwayGO:00971903060.038
epithelial tube morphogenesisGO:00605623030.038
renal system developmentGO:00720012250.038
regulation of cellular component biogenesisGO:00440871810.038
membrane organizationGO:00610242450.038
transmembrane transportGO:00550854120.038
regulation of transferase activityGO:00513382630.038
cellular amine metabolic processGO:0044106440.037
kidney developmentGO:00018222130.037
cellular lipid metabolic processGO:00442553230.036
wnt signaling pathwayGO:00160551880.035
cytokine productionGO:00018163190.035
cation transmembrane transportGO:00986552660.035
peptidyl amino acid modificationGO:00181933360.035
microtubule based processGO:00070172360.035
oxidation reduction processGO:00551143420.034
neuronal action potentialGO:0019228540.034
cellular response to organonitrogen compoundGO:00714171450.034
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.034
axonogenesisGO:00074092740.033
urogenital system developmentGO:00016552610.033
positive regulation of transferase activityGO:00513471670.033
cellular ketone metabolic processGO:0042180840.033
regulation of protein localizationGO:00328802310.033
forebrain developmentGO:00309003020.033
respiratory tube developmentGO:00303231670.033
fat cell differentiationGO:00454441600.033
single organism cell adhesionGO:00986021560.033
response to organonitrogen compoundGO:00102432460.032
regulation of hormone levelsGO:00108172110.032
positive regulation of cellular amine metabolic processGO:003324050.032
protein ubiquitinationGO:00165671710.032
modification dependent macromolecule catabolic processGO:00436321330.031
regulation of establishment of protein localizationGO:00702011810.031
positive regulation of nervous system developmentGO:00519622210.031
synaptic transmissionGO:00072683290.031
developmental growth involved in morphogenesisGO:00605601380.031
negative regulation of protein metabolic processGO:00512482820.030
negative regulation of cell proliferationGO:00082852960.030
neuron projection guidanceGO:00974851410.030
regulation of cell cycleGO:00517262810.030
regulation of cellular response to stressGO:00801351590.029
camera type eye developmentGO:00430102660.029
cell fate commitmentGO:00451652100.029
regulation of proteolysisGO:00301621640.029
homeostasis of number of cellsGO:00488722100.029
protein maturationGO:00516041760.029
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.028
regulation of neuron differentiationGO:00456642810.028
respiratory system developmentGO:00605411900.028
ion transmembrane transportGO:00342203610.028
microtubule cytoskeleton organizationGO:00002261570.027
glycoprotein metabolic processGO:00091001160.027
intracellular protein transportGO:00068862040.027
g protein coupled receptor signaling pathwayGO:00071862430.027
cognitionGO:00508901490.026
regulation of apoptotic signaling pathwayGO:20012331970.026
striated muscle tissue developmentGO:00147062930.026
regulation of transmembrane transportGO:00347621280.026
positive regulation of kinase activityGO:00336741550.026
myeloid cell differentiationGO:00300992330.026
positive regulation of protein kinase activityGO:00458601440.026
digestive system developmentGO:00551232000.026
ear developmentGO:00435832000.026
modification dependent protein catabolic processGO:00199411330.025
negative regulation of cellular protein metabolic processGO:00322692470.025
gliogenesisGO:00420631410.025
protein modification by small protein conjugationGO:00324461870.025
carbohydrate metabolic processGO:00059752300.025
regulation of ion transmembrane transporter activityGO:0032412540.024
protein catabolic processGO:00301632210.024
ubiquitin dependent protein catabolic processGO:00065111290.024
plasma membrane organizationGO:0007009900.024
positive regulation of cell developmentGO:00107202370.024
positive regulation of mapk cascadeGO:00434101700.024
cellular response to growth factor stimulusGO:00713631970.024
lung developmentGO:00303241640.024
nitrogen compound transportGO:00717052710.024
response to growth factorGO:00708481980.023
proteolysis involved in cellular protein catabolic processGO:00516031470.023
organelle fissionGO:00482851700.023
lymphocyte differentiationGO:00300982420.023
organelle localizationGO:00516401790.023
organonitrogen compound biosynthetic processGO:19015661920.023
cellular homeostasisGO:00197252400.023
positive regulation of protein serine threonine kinase activityGO:00719021060.023
gland developmentGO:00487323300.023
positive regulation of cell deathGO:00109422240.023
wound healingGO:00420601570.022
protein targetingGO:00066051430.022
embryonic organ morphogenesisGO:00485622760.022
neurotransmitter transportGO:0006836760.022
negative regulation of intracellular signal transductionGO:19025321670.022
canonical wnt signaling pathwayGO:00600701300.022
sulfur compound metabolic processGO:00067901000.022
protein localization to membraneGO:00726571080.022
establishment of organelle localizationGO:00516561220.021
regulation of secretionGO:00510462740.021
establishment or maintenance of cell polarityGO:0007163860.021
regulation of vesicle mediated transportGO:00606271390.021
carbohydrate derivative biosynthetic processGO:19011371830.021
cell substrate adhesionGO:00315891300.021
cell adhesionGO:00071553290.021
hormone secretionGO:00468791280.021
organophosphate biosynthetic processGO:00904071220.021
negative regulation of organelle organizationGO:0010639900.021
muscle cell differentiationGO:00426922610.021
cytoplasmic transportGO:00164822340.021
cellular response to hormone stimulusGO:00328701500.021
regulation of anatomical structure sizeGO:00900661780.020
negative regulation of cellular component organizationGO:00511291940.020
ensheathment of neuronsGO:0007272760.020
negative regulation of protein modification processGO:00314001630.020
rhythmic processGO:00485111740.020
endomembrane system organizationGO:00102561470.020
small gtpase mediated signal transductionGO:0007264970.020
regulation of wnt signaling pathwayGO:00301111230.020
lateral line system developmentGO:004892510.020
nucleobase containing small molecule metabolic processGO:00550863520.020
nuclear divisionGO:00002801580.020
germ cell developmentGO:00072811850.020
regulation of cell activationGO:00508652890.020
establishment of vesicle localizationGO:0051650810.020
monosaccharide metabolic processGO:00059961060.020
glial cell differentiationGO:00100011310.020
positive regulation of neuron differentiationGO:00456661410.020
sensory organ morphogenesisGO:00905962420.020
developmental maturationGO:00217001930.020
protein localization to organelleGO:00333651850.020
cell growthGO:00160491300.020
negative regulation of phosphate metabolic processGO:00459361840.019
positive regulation of programmed cell deathGO:00430682180.019
mitotic cell cycle processGO:19030471590.019
regulation of neuron projection developmentGO:00109751690.019
morphogenesis of a branching structureGO:00017632030.019
regulation of transporter activityGO:0032409570.019
inorganic cation transmembrane transportGO:00986622070.019
cellular protein complex assemblyGO:00436231160.019
lateral inhibitionGO:004633110.019
dna metabolic processGO:00062593030.019
negative regulation of phosphorus metabolic processGO:00105631840.019
cell type specific apoptotic processGO:00972852680.019
positive regulation of secretionGO:00510471300.019
developmental cell growthGO:0048588840.019
regulation of defense responseGO:00313472330.019
organic hydroxy compound metabolic processGO:19016152030.019
leukocyte differentiationGO:00025213420.019
t cell activationGO:00421102890.018
memoryGO:0007613580.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.018
locomotory behaviorGO:00076261950.018
regulation of cytokine productionGO:00018172660.018
negative regulation of cellular amine metabolic processGO:003323910.018
central nervous system neuron differentiationGO:00219531620.018
positive regulation of cellular component biogenesisGO:0044089940.018
mitotic cell cycleGO:00002781950.018
regulation of map kinase activityGO:00434051200.018
establishment of protein localization to organelleGO:00725941180.018
extracellular structure organizationGO:00430621480.018
inorganic ion transmembrane transportGO:00986602340.018
synapse organizationGO:00508081250.017
erk1 and erk2 cascadeGO:0070371770.017
positive regulation of secretion by cellGO:19035321140.017
ameboidal type cell migrationGO:00016671280.017
neuron migrationGO:00017641220.017
tube formationGO:00351481400.017
regulation of protein transportGO:00512231630.017
regulation of ion transmembrane transportGO:00347651190.017
ribonucleoside metabolic processGO:00091192450.017
gonad developmentGO:00084061410.017
hematopoietic progenitor cell differentiationGO:00022441430.017
regulation of cell substrate adhesionGO:0010810730.017
peptidyl tyrosine modificationGO:00182121450.017
actin cytoskeleton organizationGO:00300362200.017
negative regulation of cell developmentGO:00107211690.017
multicellular organismal homeostasisGO:00488711640.016
reactive oxygen species metabolic processGO:0072593840.016
learning or memoryGO:00076111480.016
regulation of cellular catabolic processGO:00313292420.016
regulation of organ morphogenesisGO:20000271440.016
peptide secretionGO:00027901140.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
positive regulation of map kinase activityGO:0043406840.016
regulation of cell migrationGO:00303342190.016
nucleoside phosphate metabolic processGO:00067533380.016
jnk cascadeGO:0007254720.016
circulatory system processGO:00030131970.016
aromatic compound catabolic processGO:00194392860.016
regulation of homeostatic processGO:00328441820.016
small molecule biosynthetic processGO:00442831320.016
response to radiationGO:00093141650.016
anatomical structure homeostasisGO:00602491450.016
peptidyl tyrosine phosphorylationGO:00181081430.016
regulation of nucleotide metabolic processGO:00061401690.016
amide transportGO:00428861380.016
blood circulationGO:00080151950.016
positive regulation of growthGO:00459271040.016
purine ribonucleotide metabolic processGO:00091502900.016
hormone metabolic processGO:0042445860.016
immune effector processGO:00022523210.016
development of primary sexual characteristicsGO:00451371430.016
cation homeostasisGO:00550802120.016
sodium ion transportGO:0006814730.015
oocyte constructionGO:000730820.015
regulation of carbohydrate metabolic processGO:0006109750.015
regulation of metal ion transportGO:00109591060.015
regulation of leukocyte differentiationGO:19021051590.015
regulation of mitotic cell cycleGO:00073461260.015
compound eye developmentGO:004874910.015
purine nucleotide metabolic processGO:00061633020.015
regulation of neuron deathGO:19012141340.015
neuromuscular processGO:0050905990.015
sensory system developmentGO:004888030.015
positive regulation of apoptotic processGO:00430652170.015
regulation of body fluid levelsGO:00508781620.015
protein secretionGO:00093061110.015
epidermis developmentGO:00085441870.015
regulation of cellular response to growth factor stimulusGO:0090287820.015
lymphocyte mediated immunityGO:00024491390.015
regulation of jnk cascadeGO:0046328620.015
response to oxidative stressGO:00069791230.015
response to organic cyclic compoundGO:00140701980.015
nucleocytoplasmic transportGO:00069131390.015
stress activated protein kinase signaling cascadeGO:0031098810.015
pallium developmentGO:00215431200.014
sensory perceptionGO:00076002450.014
exocytosisGO:00068871210.014
glycoprotein biosynthetic processGO:0009101890.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
neural precursor cell proliferationGO:00613511210.014
telencephalon developmentGO:00215371860.014
glucose metabolic processGO:0006006920.014
cellular response to peptideGO:1901653920.014
negative regulation of phosphorylationGO:00423261660.014
positive regulation of cytokine productionGO:00018191740.014
anion transportGO:00068201770.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.014
multi multicellular organism processGO:00447061090.014
peptide hormone secretionGO:00300721090.014
cellular carbohydrate metabolic processGO:00442621190.014
pigmentationGO:0043473710.014
stress activated mapk cascadeGO:0051403800.014
meiotic nuclear divisionGO:00071261150.014
response to extracellular stimulusGO:00099911270.014
asymmetric stem cell divisionGO:009872230.014
regulation of synaptic plasticityGO:0048167870.014
actin filament organizationGO:00070151130.014
chemotaxisGO:00069352470.014
response to acid chemicalGO:00011011110.014
organ growthGO:00352651170.014
response to peptide hormoneGO:00434341270.014
regulation of canonical wnt signaling pathwayGO:0060828820.014
leukocyte mediated immunityGO:00024431740.014
epithelial tube formationGO:00721751300.014
myeloid leukocyte differentiationGO:00025731190.014
defense response to other organismGO:00985421970.014
neuron deathGO:00709971540.014
skeletal system morphogenesisGO:00487052030.014
peptide transportGO:00158331330.014
positive regulation of cell motilityGO:20001471160.014
regulation of purine nucleotide metabolic processGO:19005421690.014
axon ensheathmentGO:0008366760.014
regulation of cell adhesionGO:00301551540.014
cell divisionGO:00513011200.014
divalent inorganic cation transportGO:00725111780.014
positive regulation of cell projection organizationGO:0031346950.013
localization within membraneGO:005166840.013
skeletal muscle organ developmentGO:00605381630.013
negative regulation of apoptotic signaling pathwayGO:20012341040.013
regulation of system processGO:00440572000.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
vesicle localizationGO:0051648860.013
positive regulation of nucleotide metabolic processGO:00459811140.013
t cell differentiationGO:00302171740.013
ossificationGO:00015032160.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
female sex differentiationGO:0046660840.013
regulation of protein serine threonine kinase activityGO:00719001570.013
regulation of erk1 and erk2 cascadeGO:0070372710.013
cellular response to peptide hormone stimulusGO:0071375920.013
glycerolipid metabolic processGO:00464861220.013
extracellular matrix organizationGO:00301981470.013
regulation of stress activated mapk cascadeGO:0032872690.013
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.013
regulation of ion transportGO:00432692150.013
ribose phosphate metabolic processGO:00196932910.013
response to peptideGO:19016521360.013
spermatid differentiationGO:00485151150.013
glucose homeostasisGO:00425931280.013
negative regulation of nervous system developmentGO:00519611560.013
myotube differentiationGO:00149021050.013
regulation of cytoskeleton organizationGO:00514931220.013
cell maturationGO:00484691270.013
angiogenesisGO:00015252010.013
digestive tract developmentGO:00485651900.013
posttranscriptional regulation of gene expressionGO:00106081550.013
nucleoside phosphate catabolic processGO:19012922220.013
regulation of protein catabolic processGO:00421761080.013
oocyte axis specificationGO:000730920.013
positive regulation of protein transportGO:0051222930.013
negative regulation of wnt signaling pathwayGO:0030178730.013
response to light stimulusGO:00094161350.013
appendage morphogenesisGO:00351071490.012
adult behaviorGO:00305341350.012
generation of precursor metabolites and energyGO:00060911030.012
proteasomal protein catabolic processGO:0010498980.012
myelinationGO:0042552740.012
retrograde transport endosome to golgiGO:004214720.012
endocytosisGO:00068971680.012
calcium ion homeostasisGO:00550741270.012
blastocyst developmentGO:0001824800.012
forebrain cell migrationGO:0021885580.012
blood coagulationGO:0007596760.012
ureteric bud developmentGO:0001657940.012
rho protein signal transductionGO:0007266320.012
metanephros developmentGO:0001656790.012
fibroblast growth factor receptor signaling pathwayGO:0008543460.012
regulation of peptide transportGO:0090087910.012
carbohydrate derivative catabolic processGO:19011362310.012
protein processingGO:00164851630.012
negative regulation of immune system processGO:00026832090.012
embryonic epithelial tube formationGO:00018381300.012
positive regulation of neuron projection developmentGO:0010976790.012
retina development in camera type eyeGO:00600411190.012
skeletal system developmentGO:00015013560.012
meiotic cell cycleGO:00513211220.012
neuron projection extensionGO:1990138640.012
insulin secretionGO:0030073890.012
regulation of cell growthGO:0001558910.012
rna processingGO:00063961050.012
regulation of inflammatory responseGO:00507271470.012
hexose metabolic processGO:0019318980.012
regulation of clathrin mediated endocytosisGO:200036940.012
cellular response to dna damage stimulusGO:00069742070.012
regulation of hydrolase activityGO:00513362460.012
regulation of cellular component sizeGO:00325351210.012
neuron apoptotic processGO:00514021420.012
negative regulation of protein phosphorylationGO:00019331260.012
negative regulation of cell cycleGO:00457861230.012
nuclear transportGO:00511691390.012
cellular chemical homeostasisGO:00550822150.012
cellular response to transforming growth factor beta stimulusGO:0071560880.012
defecationGO:003042110.012
cellular metal ion homeostasisGO:00068751510.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
purine containing compound metabolic processGO:00725213110.012
positive regulation of hydrolase activityGO:00513451480.012
mrna metabolic processGO:0016071840.012
regulation of ras protein signal transductionGO:00465781140.011
chondrocyte differentiationGO:0002062720.011
mesodermal cell migrationGO:000807840.011
tissue homeostasisGO:00018941150.011
epithelial cell proliferationGO:00506731740.011
methylationGO:00322591340.011
regionalizationGO:00030023370.011
regulation of ossificationGO:00302781120.011
sterol metabolic processGO:0016125580.011
regulation of fat cell differentiationGO:0045598810.011
positive regulation of fatty acid oxidationGO:004632140.011
nuclear importGO:0051170950.011
regulation of exocytosisGO:0017157610.011
regulation of cell cycle processGO:00105641600.011
bone developmentGO:00603481200.011
organic cyclic compound catabolic processGO:19013612950.011
monocarboxylic acid metabolic processGO:00327871910.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
purine nucleoside triphosphate metabolic processGO:00091442260.011
metal ion homeostasisGO:00550651890.011
fatty acid metabolic processGO:00066311210.011
positive regulation of membrane potentialGO:0045838150.011
regulation of neurotransmitter levelsGO:0001505870.011
ribonucleotide metabolic processGO:00092592910.011
purine ribonucleoside metabolic processGO:00461282410.011
divalent inorganic cation homeostasisGO:00725071380.011
regulation of epithelial cell proliferationGO:00506781410.011
protein import into nucleusGO:0006606950.011
response to nutrient levelsGO:00316671090.011
carboxylic acid biosynthetic processGO:0046394860.011
intracellular mrna localizationGO:000829840.011
cellular response to acid chemicalGO:0071229680.011
regulation of myeloid cell differentiationGO:0045637960.011
lipid biosynthetic processGO:00086101790.011
negative regulation of growthGO:0045926990.011
microtubule based movementGO:0007018840.011
regulation of response to woundingGO:19030341890.011
dephosphorylationGO:00163111290.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
metanephric loop of henle developmentGO:007223640.011
neural tube developmentGO:00219151600.011
regulation of hormone secretionGO:0046883880.011
regulation of endocytosisGO:0030100690.011
positive regulation of wnt signaling pathwayGO:0030177450.011
regulation of protein maturationGO:1903317960.011
regulation of cell motilityGO:20001452360.011
cellular response to epidermal growth factor stimulusGO:007136440.011
purine nucleoside metabolic processGO:00422782410.011
nucleotide metabolic processGO:00091173320.011
midgut developmentGO:000749440.011
alcohol metabolic processGO:00060661160.011
regulation of lipid metabolic processGO:00192161180.011
cellular response to insulin stimulusGO:0032869780.010
cellular response to oxidative stressGO:0034599760.010
cellular ion homeostasisGO:00068731650.010
chromatin organizationGO:00063252060.010
positive regulation of reactive oxygen species metabolic processGO:2000379110.010
regulation of extent of cell growthGO:0061387520.010
regulation of blood pressureGO:0008217930.010
synaptic vesicle transportGO:0048489570.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
ear morphogenesisGO:00424711180.010
sulfur compound biosynthetic processGO:0044272370.010
reactive oxygen species biosynthetic processGO:190340980.010
positive regulation of cell migrationGO:00303351090.010
calcium ion dependent exocytosisGO:0017156350.010
fertilizationGO:00095661270.010
mesonephric epithelium developmentGO:0072163940.010
gastrulationGO:00073691160.010
positive regulation of erk1 and erk2 cascadeGO:0070374470.010
learningGO:0007612980.010
epithelial cell developmentGO:00020641590.010
cardiac chamber developmentGO:00032051080.010
morphogenesis of a branching epitheliumGO:00611381930.010
tube closureGO:0060606910.010
membrane tubulationGO:009732040.010
cell cell adhesionGO:0098609410.010
transition metal ion homeostasisGO:0055076540.010
engulfment of apoptotic cellGO:004365230.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.010
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.010
response to molecule of bacterial originGO:00022371430.010
cell cell junction organizationGO:0045216720.010
regulation of feeding behaviorGO:006025930.010
development of primary female sexual characteristicsGO:0046545730.010
regulation of peptide secretionGO:0002791770.010
sensory perception of soundGO:0007605970.010
maternal determination of anterior posterior axis embryoGO:000835820.010
neural tube formationGO:00018411080.010

Mapk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
nervous system diseaseDOID:86300.023
central nervous system diseaseDOID:33100.015
disease of metabolismDOID:001466700.011
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011