Mus musculus

172 known processes

Kat2a

K(lysine) acetyltransferase 2A

(Aliases: AW212720,Gcn5l2,1110051E14Rik,Gcn5,mmGCN5)

Kat2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h3 acetylationGO:0043966141.000
histone acetylationGO:0016573411.000
histone modificationGO:00165701590.999
covalent chromatin modificationGO:00165691630.999
chromatin organizationGO:00063252060.998
internal protein amino acid acetylationGO:0006475420.994
internal peptidyl lysine acetylationGO:0018393420.990
peptidyl amino acid modificationGO:00181933360.986
protein acylationGO:0043543640.974
chromatin modificationGO:00165681870.973
peptidyl lysine modificationGO:0018205770.967
tubulin deacetylationGO:009004240.939
peptidyl lysine acetylationGO:0018394450.869
regulation of protein deacetylationGO:0090311170.833
positive regulation of gluconeogenesis by positive regulation of transcription from rna polymerase ii promoterGO:003594850.755
regulation of histone modificationGO:0031056560.689
histone h4 k16 acetylationGO:004398430.658
regulation of histone deacetylationGO:0031063120.563
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoterGO:007236470.520
histone deubiquitinationGO:001657820.519
Human
protein methylationGO:0006479810.485
mitotic cell cycleGO:00002781950.457
purine nucleoside triphosphate metabolic processGO:00091442260.356
histone h4 acetylationGO:0043967100.323
regulation of chromatin organizationGO:1902275570.317
dna metabolic processGO:00062593030.304
mitotic cell cycle processGO:19030471590.304
histone methylationGO:0016571710.286
regulation of cell cycle phase transitionGO:1901987770.238
establishment of protein localization to organelleGO:00725941180.235
regulation of organelle organizationGO:00330432890.232
regulation of chromatin modificationGO:1903308570.224
protein deacetylationGO:0006476320.219
cell cycle checkpointGO:0000075470.217
cellular ketone metabolic processGO:0042180840.201
regulation of intracellular transportGO:00323861590.189
intracellular steroid hormone receptor signaling pathwayGO:0030518290.186
nuclear divisionGO:00002801580.183
nuclear transportGO:00511691390.181
transdifferentiationGO:006029010.181
posttranscriptional regulation of gene expressionGO:00106081550.176
Human
regulation of chromosome organizationGO:0033044830.171
skeletal system developmentGO:00015013560.166
regulation of cytoplasmic transportGO:19036491120.144
single organism nuclear importGO:1902593950.143
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoterGO:003594770.137
protein alkylationGO:0008213810.133
cellular nitrogen compound catabolic processGO:00442702800.130
regulation of protein import into nucleusGO:0042306520.123
regulation of protein stabilityGO:0031647520.121
Human
regulation of establishment of protein localizationGO:00702011810.120
protein import into nucleusGO:0006606950.111
cellular amine metabolic processGO:0044106440.101
regulation of protein localizationGO:00328802310.100
guanosine containing compound catabolic processGO:19010691440.098
negative regulation of phosphorus metabolic processGO:00105631840.097
Mouse
regulation of mitotic cell cycle phase transitionGO:1901990730.097
ribonucleotide metabolic processGO:00092592910.095
apoptotic signaling pathwayGO:00971903060.092
nuclear importGO:0051170950.090
histone deacetylationGO:0016575260.090
protein localization to organelleGO:00333651850.089
negative regulation of cell cycleGO:00457861230.089
Mouse
regulation of cell cycleGO:00517262810.088
Mouse
protein localization to nucleusGO:00345041210.085
glycosyl compound metabolic processGO:19016572460.080
regulation of cellular catabolic processGO:00313292420.079
embryonic organ morphogenesisGO:00485622760.079
histone lysine methylationGO:0034968500.079
protein targetingGO:00066051430.078
regulation of nucleoside metabolic processGO:00091181300.078
mitotic cell cycle checkpointGO:0007093310.077
intracellular protein transportGO:00068862040.076
nucleocytoplasmic transportGO:00069131390.076
skeletal system morphogenesisGO:00487052030.075
regulation of purine nucleotide catabolic processGO:00331211220.074
dendrite developmentGO:00163581150.074
Fly
response to organic cyclic compoundGO:00140701980.073
protein modification by small protein removalGO:0070646210.072
Human
development of primary sexual characteristicsGO:00451371430.071
regulation of nucleocytoplasmic transportGO:0046822730.070
nucleotide catabolic processGO:00091662170.070
methylationGO:00322591340.068
gonad developmentGO:00084061410.067
protein importGO:00170381010.065
positive regulation of intracellular transportGO:0032388700.064
carbohydrate derivative catabolic processGO:19011362310.063
purine containing compound metabolic processGO:00725213110.063
negative regulation of phosphorylationGO:00423261660.063
Mouse
nucleoside phosphate metabolic processGO:00067533380.060
organonitrogen compound biosynthetic processGO:19015661920.059
regulation of cell cycle processGO:00105641600.058
regulation of hydrolase activityGO:00513362460.057
purine ribonucleoside catabolic processGO:00461302050.056
cellular macromolecule catabolic processGO:00442652060.055
response to reactive oxygen speciesGO:0000302560.054
regulation of defense response to bacteriumGO:190042430.053
stem cell developmentGO:00488642190.053
macromolecule methylationGO:00434141200.052
regulation of cellular amine metabolic processGO:0033238200.052
organelle fissionGO:00482851700.051
nucleoside metabolic processGO:00091162460.051
antimicrobial peptide productionGO:000277520.051
positive regulation of hydrolase activityGO:00513451480.048
protein modification by small protein conjugation or removalGO:00706472070.048
Human
regulation of protein transportGO:00512231630.048
macromolecule deacylationGO:0098732370.046
regulation of mitotic cell cycleGO:00073461260.046
ribonucleotide catabolic processGO:00092612080.045
purine nucleoside metabolic processGO:00422782410.044
negative regulation of cell cycle processGO:0010948690.044
ribose phosphate metabolic processGO:00196932910.044
regulation of cellular ketone metabolic processGO:0010565660.044
anatomical structure homeostasisGO:00602491450.042
positive regulation of apoptotic processGO:00430652170.040
heterocycle catabolic processGO:00467002800.040
positive regulation of gtp catabolic processGO:0033126850.039
spermatogenesisGO:00072832840.039
positive regulation of gtpase activityGO:0043547850.039
cell divisionGO:00513011200.038
positive regulation of programmed cell deathGO:00430682180.037
positive regulation of defense response to bacteriumGO:190042610.037
regulation of protein targetingGO:1903533610.037
nucleoside triphosphate metabolic processGO:00091412300.037
rrna transcriptionGO:000930390.037
amine metabolic processGO:0009308450.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
cellular protein catabolic processGO:00442571550.036
aromatic compound catabolic processGO:00194392860.036
positive regulation of nucleoside metabolic processGO:0045979910.036
cell cycle g2 m phase transitionGO:0044839200.036
maintenance of locationGO:0051235890.035
cajal body organizationGO:003057610.035
negative regulation of phosphate metabolic processGO:00459361840.035
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.035
nucleotide metabolic processGO:00091173320.035
protein deubiquitinationGO:0016579190.034
Human
cellular carbohydrate metabolic processGO:00442621190.034
regulation of purine nucleotide metabolic processGO:19005421690.034
positive regulation of intracellular protein transportGO:0090316420.034
regulation of protein serine threonine kinase activityGO:00719001570.033
Mouse
cellular amino acid metabolic processGO:00065201030.033
stem cell differentiationGO:00488632680.033
carbohydrate biosynthetic processGO:0016051740.033
dna integrity checkpointGO:0031570280.033
regulation of anatomical structure sizeGO:00900661780.033
regulation of endopeptidase activityGO:0052548890.033
positive regulation of growthGO:00459271040.033
sensory organ morphogenesisGO:00905962420.033
hexose metabolic processGO:0019318980.032
intracellular receptor signaling pathwayGO:0030522740.032
purine containing compound catabolic processGO:00725232130.032
mitotic nuclear divisionGO:0007067480.031
organic cyclic compound catabolic processGO:19013612950.031
cellular response to oxygen radicalGO:0071450140.030
male gamete generationGO:00482322850.030
positive regulation of cellular catabolic processGO:00313311480.030
regulation of intracellular protein transportGO:0033157820.030
nucleoside catabolic processGO:00091642060.030
leukocyte differentiationGO:00025213420.029
cellular response to transforming growth factor beta stimulusGO:0071560880.029
nucleoside triphosphate catabolic processGO:00091432050.028
embryonic skeletal system developmentGO:00487061200.028
innate immune responseGO:00450871570.027
nucleobase containing small molecule metabolic processGO:00550863520.027
positive regulation of protein modification processGO:00314012990.027
gland developmentGO:00487323300.027
rna processingGO:00063961050.027
purine nucleoside triphosphate catabolic processGO:00091462030.027
ribonucleoside triphosphate metabolic processGO:00091992200.026
chemotaxisGO:00069352470.026
mitochondrion organizationGO:00070051340.026
positive regulation of organelle organizationGO:00106381280.026
negative regulation of cell proliferationGO:00082852960.026
regulation of antimicrobial humoral responseGO:000275930.026
regulation of cellular amino acid metabolic processGO:000652150.026
positive regulation of gluconeogenesisGO:0045722110.026
purine ribonucleotide metabolic processGO:00091502900.025
microtubule based processGO:00070172360.025
protein processingGO:00164851630.025
guanosine containing compound metabolic processGO:19010681440.025
endonucleolytic cleavage involved in rrna processingGO:000047810.025
ribonucleoside metabolic processGO:00091192450.024
multicellular organismal homeostasisGO:00488711640.023
positive regulation of protein phosphorylationGO:00019342420.023
positive regulation of protein transportGO:0051222930.023
negative regulation of apoptotic signaling pathwayGO:20012341040.023
macromolecule catabolic processGO:00090572810.023
tissue remodelingGO:00487711020.023
histone h3 k4 methylationGO:0051568230.022
protein maturationGO:00516041760.022
cellular response to oxidative stressGO:0034599760.022
axonogenesisGO:00074092740.022
Fly
response to organonitrogen compoundGO:00102432460.022
cellular response to external stimulusGO:0071496880.022
response to temperature stimulusGO:0009266550.022
regulation of protein localization to nucleusGO:1900180600.022
positive regulation of chromosome segregationGO:005198440.022
response to oxidative stressGO:00069791230.022
positive regulation of protein import into nucleusGO:0042307260.022
negative regulation of cellular protein metabolic processGO:00322692470.021
Mouse
regulation of proteolysisGO:00301621640.021
cellular response to cytokine stimulusGO:00713451890.021
localization within membraneGO:005166840.021
chromatin remodelingGO:0006338320.021
Fly
positive regulation of cellular amine metabolic processGO:003324050.021
sensory perceptionGO:00076002450.021
regulation of histone methylationGO:0031060300.021
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
positive regulation of nucleotide catabolic processGO:0030813880.021
negative regulation of cell cycle phase transitionGO:1901988480.021
post embryonic retina morphogenesis in camera type eyeGO:006006030.021
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.021
regulation of mammary gland epithelial cell proliferationGO:0033599120.021
regulation of organ morphogenesisGO:20000271440.021
circadian regulation of gene expressionGO:0032922480.020
cellular response to organic cyclic compoundGO:0071407870.020
microtubule cytoskeleton organizationGO:00002261570.020
negative regulation of synapse assemblyGO:005196430.020
stem cell maintenanceGO:00198271300.020
mammary gland epithelium developmentGO:0061180650.020
genitalia developmentGO:0048806370.020
response to heatGO:0009408270.020
telomere maintenanceGO:0000723190.020
negative regulation of neuron deathGO:1901215980.019
epithelial cell proliferationGO:00506731740.019
regulation of epithelial cell proliferationGO:00506781410.019
positive regulation of antimicrobial peptide productionGO:000222510.019
cytoplasmic transportGO:00164822340.019
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.019
purine ribonucleotide catabolic processGO:00091542080.019
blastocyst developmentGO:0001824800.019
monosaccharide metabolic processGO:00059961060.018
protein deacylationGO:0035601360.018
muscle tissue developmentGO:00605373080.018
ossificationGO:00015032160.018
signal transduction by p53 class mediatorGO:0072331510.018
purine nucleoside catabolic processGO:00061522050.018
regulation of cell motilityGO:20001452360.018
regulation of homeostatic processGO:00328441820.018
cation homeostasisGO:00550802120.018
regulation of neuron deathGO:19012141340.018
meiosis iGO:0007127600.018
dna replication independent nucleosome assemblyGO:000633610.018
regulation of cytoskeleton organizationGO:00514931220.018
cognitionGO:00508901490.018
cellular response to lipidGO:00713961450.017
cellular ion homeostasisGO:00068731650.017
organophosphate catabolic processGO:00464342320.017
symbiosis encompassing mutualism through parasitismGO:0044403830.017
embryonic skeletal system morphogenesisGO:0048704910.017
cellular response to dna damage stimulusGO:00069742070.017
histone h3 k9 acetylationGO:004397050.017
Mouse
regulation of cellular response to stressGO:00801351590.017
neuron deathGO:00709971540.017
monosaccharide biosynthetic processGO:0046364440.017
metal ion homeostasisGO:00550651890.017
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.017
cellular response to vitamin dGO:007130520.017
interspecies interaction between organismsGO:0044419830.016
regulation of gtp catabolic processGO:00331241130.016
regulation of cell sizeGO:0008361720.016
positive regulation of cellular carbohydrate metabolic processGO:0010676290.016
proteasomal protein catabolic processGO:0010498980.016
meiotic cell cycleGO:00513211220.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
cellular homeostasisGO:00197252400.016
purine nucleotide metabolic processGO:00061633020.016
nitrogen compound transportGO:00717052710.016
positive regulation of nucleotide metabolic processGO:00459811140.016
regulation of apoptotic signaling pathwayGO:20012331970.016
small gtpase mediated signal transductionGO:0007264970.016
regulation of nucleotide metabolic processGO:00061401690.016
negative regulation of proteolysisGO:0045861740.016
purine nucleotide catabolic processGO:00061952110.016
regulation of nucleotide catabolic processGO:00308111220.015
response to peptideGO:19016521360.015
negative regulation of protein phosphorylationGO:00019331260.015
Mouse
receptor mediated endocytosisGO:0006898510.015
calcium ion homeostasisGO:00550741270.015
cellular response to growth factor stimulusGO:00713631970.015
regulation of transferase activityGO:00513382630.015
Mouse
intrinsic apoptotic signaling pathwayGO:00971931320.015
gtp catabolic processGO:00061841430.015
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.015
cellular calcium ion homeostasisGO:00068741190.015
protein catabolic processGO:00301632210.015
negative regulation of mitotic cell cycle phase transitionGO:1901991450.015
negative regulation of molecular functionGO:00440922580.015
Mouse
purine ribonucleoside metabolic processGO:00461282410.015
negative regulation of protein maturationGO:1903318790.015
cytokine productionGO:00018163190.015
energy derivation by oxidation of organic compoundsGO:0015980770.015
dna methylationGO:0006306430.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
regulation of cytokine productionGO:00018172660.015
synapsisGO:0007129340.015
response to transforming growth factor betaGO:0071559880.014
multi multicellular organism processGO:00447061090.014
skin developmentGO:00435882200.014
regulation of myeloid leukocyte differentiationGO:0002761580.014
cellular response to organonitrogen compoundGO:00714171450.014
bone resorptionGO:0045453380.014
regulation of protein catabolic processGO:00421761080.014
regulation of myeloid cell differentiationGO:0045637960.014
striated muscle tissue developmentGO:00147062930.014
nls bearing protein import into nucleusGO:000660720.014
positive regulation of cell deathGO:00109422240.014
negative regulation of kinase activityGO:0033673810.014
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
g1 s transition of mitotic cell cycleGO:0000082570.014
regulation of mitochondrion organizationGO:0010821270.014
regulation of cysteine type endopeptidase activityGO:2000116650.014
digestive tract developmentGO:00485651900.014
tissue homeostasisGO:00018941150.014
ribonucleoside catabolic processGO:00424542060.014
regulation of peptidase activityGO:0052547960.014
gtp metabolic processGO:00460391440.014
regulation of vitamin d receptor signaling pathwayGO:007056220.013
cellular response to hormone stimulusGO:00328701500.013
developmental growth involved in morphogenesisGO:00605601380.013
chromatin mediated maintenance of transcriptionGO:004809620.013
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.013
Mouse
regulation of ras protein signal transductionGO:00465781140.013
g2 m transition of mitotic cell cycleGO:0000086200.013
epidermis developmentGO:00085441870.013
rhythmic processGO:00485111740.013
canonical wnt signaling pathwayGO:00600701300.013
nucleic acid phosphodiester bond hydrolysisGO:0090305490.013
positive regulation of fibroblast proliferationGO:0048146200.013
negative regulation of intracellular signal transductionGO:19025321670.013
nucleolus organizationGO:000700050.013
cell cycle arrestGO:0007050370.013
cellular response to nutrient levelsGO:0031669640.013
nucleus organizationGO:0006997450.013
primary neural tube formationGO:0014020950.013
habituationGO:004695930.012
cell growthGO:00160491300.012
heart processGO:0003015940.012
peptidyl lysine methylationGO:0018022290.012
regulation of antimicrobial peptide productionGO:000278410.012
chromatin silencingGO:0006342150.012
glycosyl compound catabolic processGO:19016582060.012
dna damage checkpointGO:0000077260.012
circulatory system processGO:00030131970.012
myeloid leukocyte differentiationGO:00025731190.012
regulation of rna export from nucleusGO:004683140.012
immune effector processGO:00022523210.012
mitotic g2 dna damage checkpointGO:000709580.012
mitotic cytokinesisGO:000028140.012
rna phosphodiester bond hydrolysisGO:0090501190.012
cellular response to peptide hormone stimulusGO:0071375920.012
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.012
rna interferenceGO:001624620.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.011
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.011
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000047910.011
pyrimidine nucleobase metabolic processGO:000620630.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
positive regulation of antimicrobial humoral responseGO:000276020.011
regulation of bindingGO:00510981110.011
positive regulation of protein localization to nucleusGO:1900182300.011
rna 5 end processingGO:000096610.011
regulation of multi organism processGO:00439001110.011
regulation of map kinase activityGO:00434051200.011
cellular response to alcoholGO:0097306230.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.011
transmembrane transportGO:00550854120.011
phagocytosisGO:0006909660.011
hatchingGO:003518840.011
neural tube developmentGO:00219151600.011
regulation of kinase activityGO:00435492490.011
Mouse
chromosome organization involved in meiosisGO:0070192390.011
mitochondrion transport along microtubuleGO:004749730.010
regulation of protein kinase activityGO:00458592320.010
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.010
regulation of glucose metabolic processGO:0010906600.010
mapk cascadeGO:00001652810.010
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.010
neural retina developmentGO:0003407410.010
atp metabolic processGO:0046034750.010
regulation of ossificationGO:00302781120.010
cell cycle g1 s phase transitionGO:0044843570.010
hexose biosynthetic processGO:0019319390.010

Kat2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.012
gastrointestinal system cancerDOID:311900.012
cancerDOID:16200.012
eye diseaseDOID:561400.012
sensory system diseaseDOID:005015500.012
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012
retinal diseaseDOID:567900.012
retinal degenerationDOID:846600.012
eye and adnexa diseaseDOID:149200.012
large intestine cancerDOID:567200.011
intestinal cancerDOID:1015500.011