Mus musculus

186 known processes

Cdkn1b

cyclin-dependent kinase inhibitor 1B

(Aliases: AI843786,p27,Kip1,AA408329,p27Kip1)

Cdkn1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of somitogenesisGO:001480761.000
regulation of cellular ketone metabolic processGO:0010565661.000
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.999
cellular response to dna damage stimulusGO:00069742070.999
Mouse
t cell activationGO:00421102890.999
mitotic cell cycleGO:00002781950.999
regulation of insulin receptor signaling pathwayGO:0046626210.997
regionalizationGO:00030023370.997
response to ionizing radiationGO:0010212420.995
Mouse
regulation of kinase activityGO:00435492490.994
negative regulation of cell proliferationGO:00082852960.993
negative regulation of protein phosphorylationGO:00019331260.992
regulation of fat cell differentiationGO:0045598810.991
signal transduction by p53 class mediatorGO:0072331510.990
Mouse
cellular ketone metabolic processGO:0042180840.990
negative regulation of fat cell differentiationGO:0045599360.990
lymphocyte differentiationGO:00300982420.989
regulation of mitotic cell cycleGO:00073461260.989
Human Mouse
regulation of transferase activityGO:00513382630.988
liver developmentGO:0001889660.987
mitotic g1 dna damage checkpointGO:003157140.986
regulation of feeding behaviorGO:006025930.985
negative regulation of protein serine threonine kinase activityGO:0071901490.985
cellular response to peptideGO:1901653920.985
negative regulation of kinase activityGO:0033673810.985
negative regulation of cell cycle phase transitionGO:1901988480.984
negative regulation of growthGO:0045926990.983
Human
negative regulation of transferase activityGO:0051348850.983
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.982
Mouse
regulation of hydrolase activityGO:00513362460.982
Human
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.981
gland developmentGO:00487323300.980
regulation of bmp signaling pathwayGO:0030510600.979
response to testosteroneGO:003357430.978
negative regulation of leukocyte differentiationGO:1902106510.978
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.977
negative regulation of cell cycleGO:00457861230.977
response to x rayGO:0010165110.976
g1 s transition of mitotic cell cycleGO:0000082570.976
regulation of cell cycleGO:00517262810.976
cyclic purine nucleotide metabolic processGO:0052652430.975
regulation of cohesin localization to chromatinGO:007192210.974
regulation of protein import into nucleus translocationGO:003315820.972
Mouse
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoterGO:007236470.970
intrinsic apoptotic signaling pathwayGO:00971931320.970
Mouse
tyrosine phosphorylation of stat1 proteinGO:004250830.968
cohesin localization to chromatinGO:007192110.966
negative regulation of insulin receptor signaling pathwayGO:0046627140.963
positive regulation of peptide hormone secretionGO:0090277310.963
negative regulation of phosphorylationGO:00423261660.961
fat cell differentiationGO:00454441600.961
apoptotic signaling pathwayGO:00971903060.958
Mouse
response to nutrient levelsGO:00316671090.957
dna damage checkpointGO:0000077260.953
wnt signaling pathwayGO:00160551880.951
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.949
monosaccharide metabolic processGO:00059961060.947
regulation of cellular amino acid metabolic processGO:000652150.947
cellular amino acid metabolic processGO:00065201030.944
regulation of cell cycle processGO:00105641600.942
regulation of epithelial cell proliferation involved in prostate gland developmentGO:0060768100.941
cellular response to hormone stimulusGO:00328701500.938
regulation of cell cycle phase transitionGO:1901987770.935
cellular response to peptide hormone stimulusGO:0071375920.934
erythrocyte differentiationGO:0030218880.933
response to peptideGO:19016521360.931
regulation of nucleocytoplasmic transportGO:0046822730.930
Mouse
regulation of triglyceride metabolic processGO:0090207170.930
somitogenesisGO:0001756690.929
macroautophagyGO:0016236210.926
mitotic cell cycle processGO:19030471590.922
insulin secretionGO:0030073890.922
jak stat cascadeGO:0007259420.921
positive regulation of cell cycleGO:0045787920.919
intra s dna damage checkpointGO:003157340.918
microtubule based processGO:00070172360.917
multicellular organism growthGO:00352641610.917
regulation of protein kinase activityGO:00458592320.914
lactationGO:0007595250.914
leukocyte proliferationGO:00706611720.912
Mouse
male gamete generationGO:00482322850.909
negative regulation of glial cell proliferationGO:006025340.906
response to organonitrogen compoundGO:00102432460.904
negative regulation of oligodendrocyte differentiationGO:0048715110.904
regulation of mitotic cell cycle phase transitionGO:1901990730.903
positive regulation of transferase activityGO:00513471670.900
germ cell developmentGO:00072811850.899
neuron deathGO:00709971540.897
negative regulation of mitotic cell cycleGO:0045930580.889
Human
positive regulation of kinase activityGO:00336741550.889
enucleate erythrocyte differentiationGO:004335380.889
cellular response to cytokine stimulusGO:00713451890.888
carbohydrate homeostasisGO:00335001280.884
dna damage response signal transduction by p53 class mediatorGO:0030330190.883
regulation of cellular amine metabolic processGO:0033238200.881
cellular glucan metabolic processGO:0006073320.876
insulin receptor signaling pathwayGO:0008286490.876
somite developmentGO:0061053810.873
cell cycle arrestGO:0007050370.870
negative regulation of auditory receptor cell differentiationGO:004560820.867
negative regulation of cell cycle arrestGO:007115710.865
negative regulation of epithelial cell proliferationGO:0050680640.864
canonical wnt signaling pathwayGO:00600701300.863
negative regulation of t cell differentiationGO:0045581230.861
regulation of cell morphogenesis involved in differentiationGO:00107691510.861
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.857
Mouse
cyclic nucleotide biosynthetic processGO:0009190440.856
mammary gland epithelium developmentGO:0061180650.854
negative regulation of epithelial cell proliferation involved in prostate gland developmentGO:006077070.853
positive regulation of cell developmentGO:00107202370.851
creatine metabolic processGO:000660040.849
positive regulation of camp metabolic processGO:0030816190.848
cell growthGO:00160491300.848
Human
mitotic cell cycle checkpointGO:0007093310.847
positive regulation of bmp signaling pathwayGO:0030513230.845
positive regulation of apoptotic signaling pathwayGO:2001235950.844
acylglycerol metabolic processGO:0006639550.839
response to extracellular stimulusGO:00099911270.838
mitotic cell cycle arrestGO:007185040.837
Human Mouse
positive regulation of epithelial cell proliferationGO:0050679680.835
lymphocyte proliferationGO:00466511640.833
Mouse
regulation of lymphocyte activationGO:00512492400.833
Mouse
t cell differentiationGO:00302171740.832
cellular senescenceGO:0090398110.831
regulation of cellular catabolic processGO:00313292420.830
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.830
spermatogenesisGO:00072832840.829
hepaticobiliary system developmentGO:0061008670.824
cellular amine metabolic processGO:0044106440.821
epithelial tube morphogenesisGO:00605623030.819
cell cycle g1 s phase transitionGO:0044843570.818
regulation of cellular response to stressGO:00801351590.816
response to insulinGO:00328681000.816
b cell proliferationGO:0042100530.813
Mouse
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.812
regulation of intracellular transportGO:00323861590.809
Mouse
negative regulation of blood vessel endothelial cell migrationGO:004353730.802
regulation of lymphocyte proliferationGO:00506701170.795
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.795
negative regulation of phosphorus metabolic processGO:00105631840.794
peripheral nervous system neuron axonogenesisGO:004893630.793
carbohydrate derivative biosynthetic processGO:19011371830.792
stem cell developmentGO:00488642190.792
hormone mediated signaling pathwayGO:0009755230.792
positive regulation of protein modification processGO:00314012990.787
cell divisionGO:00513011200.782
radial glial cell differentiationGO:006001960.782
activation of janus kinase activityGO:004297620.781
androgen receptor signaling pathwayGO:003052180.780
stem cell differentiationGO:00488632680.780
stem cell maintenanceGO:00198271300.779
regulation of neural precursor cell proliferationGO:2000177700.777
forebrain radial glial cell differentiationGO:002186140.771
negative regulation of pancreatic a cell differentiationGO:200022710.769
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.768
positive regulation of mitotic cell cycleGO:0045931410.765
regulation of apoptotic signaling pathwayGO:20012331970.765
cell cycle checkpointGO:0000075470.764
cellular response to growth factor stimulusGO:00713631970.763
embryonic organ morphogenesisGO:00485622760.756
regulation of lipid metabolic processGO:00192161180.755
sensory organ morphogenesisGO:00905962420.752
dna integrity checkpointGO:0031570280.750
glucose homeostasisGO:00425931280.748
t cell proliferationGO:00420981200.747
generation of precursor metabolites and energyGO:00060911030.744
protein localization to organelleGO:00333651850.743
Mouse
rhythmic processGO:00485111740.739
positive regulation of hormone secretionGO:0046887380.737
myeloid cell differentiationGO:00300992330.736
regulation of jak stat cascadeGO:0046425340.735
negative regulation of lymphocyte differentiationGO:0045620320.735
positive regulation of mitotic sister chromatid separationGO:190197020.734
regulation of androgen receptor signaling pathwayGO:006076530.734
midbrain hindbrain boundary morphogenesisGO:002155540.732
positive regulation of histone h3 k9 methylationGO:005157440.727
positive regulation of cellular amine metabolic processGO:003324050.727
specification of loop of henle identityGO:007208640.726
prostate gland morphogenetic growthGO:006073740.722
regulation of glucose metabolic processGO:0010906600.722
hexose biosynthetic processGO:0019319390.718
positive regulation of protein kinase activityGO:00458601440.716
positive regulation of protein phosphorylationGO:00019342420.715
positive regulation of programmed cell deathGO:00430682180.713
Human Mouse
positive regulation of b cell proliferationGO:0030890240.712
Mouse
negative regulation of cellular senescenceGO:200077330.711
cellular polysaccharide metabolic processGO:0044264380.710
regulation of g1 s transition of mitotic cell cycleGO:2000045350.709
regulation of stomach neuroendocrine cell differentiationGO:006110510.708
triglyceride metabolic processGO:0006641510.707
regulation of notch signaling pathwayGO:0008593350.704
cellular carbohydrate metabolic processGO:00442621190.703
mammary gland lobule developmentGO:0061377220.703
regulation of wnt signaling pathwayGO:00301111230.699
response to peptide hormoneGO:00434341270.698
maintenance of epithelial cell apical basal polarityGO:004519920.694
regulation of lipid kinase activityGO:0043550140.693
epithelial cell proliferationGO:00506731740.687
cellular response to nutrient levelsGO:0031669640.686
carbohydrate metabolic processGO:00059752300.683
muscle cell differentiationGO:00426922610.681
positive regulation of protein serine threonine kinase activityGO:00719021060.680
prostate gland developmentGO:0030850480.679
somite specificationGO:000175740.679
pole plasm assemblyGO:000731520.676
creatinine metabolic processGO:004644930.674
regulation of camp metabolic processGO:0030814300.673
polysaccharide metabolic processGO:0005976390.672
b cell activationGO:00421131610.672
Mouse
microtubule cytoskeleton organizationGO:00002261570.669
development of primary female sexual characteristicsGO:0046545730.667
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.665
positive regulation of cell deathGO:00109422240.664
Human Mouse
notch signaling pathwayGO:0007219710.664
regulation of fatty acid metabolic processGO:0019217280.662
positive regulation of carbohydrate metabolic processGO:0045913300.661
camp biosynthetic processGO:0006171310.661
regulation of response to woundingGO:19030341890.661
negative regulation of organ growthGO:0046621170.661
negative regulation of mitotic cell cycle phase transitionGO:1901991450.659
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.656
male gonad developmentGO:0008584880.656
segmentationGO:0035282930.653
cellular response to organonitrogen compoundGO:00714171450.652
negative regulation of endothelial cell migrationGO:001059640.650
signal transduction in absence of ligandGO:0038034550.648
negative regulation of g1 s transition of mitotic cell cycleGO:2000134180.645
regulation of protein serine threonine kinase activityGO:00719001570.645
organophosphate biosynthetic processGO:00904071220.644
negative regulation of glial cell differentiationGO:0045686210.644
glycerolipid metabolic processGO:00464861220.643
positive regulation of apoptotic processGO:00430652170.642
Human
positive regulation of endothelial cell proliferationGO:0001938170.641
fibroblast proliferationGO:0048144350.639
regulation of gliogenesisGO:0014013500.636
small gtpase mediated signal transductionGO:0007264970.635
negative regulation of cell growthGO:0030308440.635
Human
negative regulation of cellular response to insulin stimulusGO:1900077160.631
signal transduction involved in dna damage checkpointGO:007242230.629
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.628
negative regulation of cellular amine metabolic processGO:003323910.626
regulation of fatty acid oxidationGO:0046320100.623
glomerulus developmentGO:0032835400.617
gluconeogenesisGO:0006094390.616
dna metabolic processGO:00062593030.613
Mouse
amine metabolic processGO:0009308450.612
regulation of nucleotide biosynthetic processGO:0030808340.612
nuclear transportGO:00511691390.611
Mouse
cellular macromolecule catabolic processGO:00442652060.606
response to vitamin dGO:003328030.604
negative regulation of phosphate metabolic processGO:00459361840.603
regulation of transcription by galactoseGO:000040910.601
neuroblast fate determinationGO:000740010.599
regulation of adenylate cyclase activityGO:0045761100.599
stat protein import into nucleusGO:000726260.596
negative regulation of molecular functionGO:00440922580.594
dna biosynthetic processGO:0071897220.592
Mouse
positive regulation of fibroblast proliferationGO:0048146200.591
response to ketoneGO:1901654150.587
negative regulation of protein processingGO:0010955790.587
formation of radial glial scaffoldsGO:002194340.587
lipid biosynthetic processGO:00086101790.586
negative regulation of fatty acid metabolic processGO:0045922100.585
neuron apoptotic processGO:00514021420.581
regulation of peptide secretionGO:0002791770.577
central nervous system myelinationGO:0022010120.575
regulation of cell growthGO:0001558910.565
Human
regulation of carbohydrate metabolic processGO:0006109750.562
cell adhesionGO:00071553290.561
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.559
regulation of gluconeogenesisGO:0006111300.559
negative regulation of inner ear receptor cell differentiationGO:200098130.557
prolactin signaling pathwayGO:003816150.555
response to light stimulusGO:00094161350.548
Mouse
sprouting angiogenesisGO:0002040260.548
stem cell proliferationGO:00720891170.546
antral ovarian follicle growthGO:000154750.546
circadian regulation of gene expressionGO:0032922480.543
negative regulation of cell motilityGO:2000146610.538
response to alcoholGO:0097305480.534
stomach neuroendocrine cell differentiationGO:006110220.533
regulation of epithelial cell proliferationGO:00506781410.532
negative regulation of astrocyte differentiationGO:0048712100.529
peptidyl tyrosine phosphorylationGO:00181081430.526
regulation of cell cycle g1 s phase transitionGO:1902806350.524
positive regulation of insulin receptor signaling pathwayGO:004662840.522
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771240.518
Mouse
microtubule polymerization or depolymerizationGO:0031109260.517
development of primary sexual characteristicsGO:00451371430.516
nuclear importGO:0051170950.512
Mouse
regulation of oligodendrocyte differentiationGO:0048713230.510
negative regulation of protein metabolic processGO:00512482820.509
negative regulation of systemic arterial blood pressureGO:0003085150.509
regulation of macroautophagyGO:0016241120.507
negative regulation of gliogenesisGO:0014014230.504
organ regenerationGO:003110020.503
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433640.503
negative regulation of stomach neuroendocrine cell differentiationGO:006110610.503
monosaccharide biosynthetic processGO:0046364440.502
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoterGO:003594770.502
ossificationGO:00015032160.501
innate immune responseGO:00450871570.500
response to corticosteroidGO:0031960200.498
signal transduction involved in mitotic dna damage checkpointGO:190240230.498
positive regulation of mitotic cell cycle embryonicGO:004597720.497
succinate metabolic processGO:000610540.494
extrinsic apoptotic signaling pathwayGO:00971911260.493
regulation of cell divisionGO:0051302760.492
mammary gland alveolus developmentGO:0060749220.492
regulation of cell migrationGO:00303342190.490
signal transduction involved in dna integrity checkpointGO:007240130.490
regulation of pro b cell differentiationGO:200097350.488
axonogenesisGO:00074092740.485
positive regulation of mitotic metaphase anaphase transitionGO:004584220.484
regulation of secretion by cellGO:19035302490.484
leukocyte differentiationGO:00025213420.483
enteroendocrine cell differentiationGO:0035883160.483
negative regulation of response to dna damage stimulusGO:2001021100.482
cellular homeostasisGO:00197252400.480
regulation of response to dna damage stimulusGO:2001020340.480
negative regulation of cell activationGO:00508661110.477
oligodendrocyte developmentGO:0014003200.475
negative regulation of protein modification processGO:00314001630.474
regulation of b cell proliferationGO:0030888390.468
Mouse
glial cell apoptotic processGO:003434930.467
cellular response to extracellular stimulusGO:0031668810.462
nuclear divisionGO:00002801580.461
development of primary male sexual characteristicsGO:0046546880.460
endothelial tube morphogenesisGO:006115420.459
negative regulation of mechanoreceptor differentiationGO:004563230.458
positive regulation of cellular amino acid metabolic processGO:004576430.458
response to oxygen levelsGO:0070482620.456
hexose metabolic processGO:0019318980.456
protein maturationGO:00516041760.456
Human
positive regulation of macrophage differentiationGO:004565150.456
positive regulation of lipid catabolic processGO:005099660.455
regulation of protein processingGO:0070613960.454
epithelial cell differentiation involved in prostate gland developmentGO:0060742130.453
regulation of neuron apoptotic processGO:00435231220.444
regulation of cysteine type endopeptidase activityGO:2000116650.442
Human
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.441
regulation of intrinsic apoptotic signaling pathway in response to dna damageGO:1902229140.440
camp metabolic processGO:0046058400.437
segment specificationGO:0007379150.437
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.437
cell fate determinationGO:0001709320.435
positive regulation of dephosphorylationGO:003530660.431
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.430
maintenance of locationGO:0051235890.429
protein autophosphorylationGO:0046777610.429
positive regulation of gluconeogenesisGO:0045722110.427
glycogen metabolic processGO:0005977320.427
homeostasis of number of cellsGO:00488722100.426
organic cyclic compound catabolic processGO:19013612950.424
nucleotide biosynthetic processGO:0009165780.422
heterocycle catabolic processGO:00467002800.422
response to radiationGO:00093141650.421
Mouse
regulation of peptidyl tyrosine phosphorylationGO:0050730930.421
regulation of transcription involved in cell fate commitmentGO:0060850150.419
regulation of leukocyte differentiationGO:19021051590.417
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.415
glandular epithelial cell differentiationGO:0002067380.415
reactive oxygen species metabolic processGO:0072593840.414
Mouse
regulation of t cell differentiationGO:0045580830.413
skeletal muscle cell differentiationGO:0035914660.413
positive regulation of neuron apoptotic processGO:0043525250.412
type i pneumocyte differentiationGO:006050970.408
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.404
blood vessel morphogenesisGO:00485142850.403
peptide transportGO:00158331330.401
bmp signaling pathwayGO:0030509930.400
gliogenesisGO:00420631410.400
protein localization to nucleusGO:00345041210.395
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.394
tyrosine phosphorylation of stat proteinGO:0007260230.393
intracellular steroid hormone receptor signaling pathwayGO:0030518290.390
mitotic spindle organizationGO:0007052100.389
prostate gland growthGO:0060736130.389
regulation of histone methylationGO:0031060300.388
positive regulation of stress fiber assemblyGO:005149690.388
inner ear receptor cell differentiationGO:0060113610.388
purine nucleotide biosynthetic processGO:0006164650.387
actin cytoskeleton reorganizationGO:0031532210.386
morphogenesis of a branching structureGO:00017632030.386
lipid localizationGO:00108761260.385
cellular response to growth hormone stimulusGO:007137870.383
signal transduction involved in cell cycle checkpointGO:007239530.383
response to uvGO:0009411440.383
Mouse
positive regulation of neuron differentiationGO:00456661410.382
negative regulation of immune system processGO:00026832090.381
positive regulation of organelle organizationGO:00106381280.375
inositol lipid mediated signalingGO:0048017410.374
energy reserve metabolic processGO:0006112390.374
regulation of auditory receptor cell differentiationGO:004560740.371
immature b cell differentiationGO:0002327100.370
positive regulation of osteoblast differentiationGO:0045669340.369
forebrain developmentGO:00309003020.369
somatic stem cell maintenanceGO:0035019470.369
purine nucleoside metabolic processGO:00422782410.368
positive regulation of histone methylationGO:0031062160.367
negative regulation of fibroblast migrationGO:001076420.366
learning or memoryGO:00076111480.365
circadian rhythmGO:00076231140.365
response to corticosteroneGO:005141210.364
apoptotic process involved in mammary gland involutionGO:006005740.364
regulation of canonical wnt signaling pathwayGO:0060828820.364
positive regulation of macrophage apoptotic processGO:200011130.361
glucose metabolic processGO:0006006920.361
locomotor rhythmGO:004547580.361
hormone secretionGO:00468791280.360
regulation of cell adhesionGO:00301551540.358
somite rostral caudal axis specificationGO:0032525130.356
regulation of t cell activationGO:00508631700.356
activation of jak2 kinase activityGO:004297720.355
hindbrain radial glia guided cell migrationGO:0021932120.353
valine metabolic processGO:000657340.349
chromatin silencingGO:0006342150.349
positive regulation of glial cell proliferationGO:006025240.347
ear developmentGO:00435832000.346
columnar cuboidal epithelial cell differentiationGO:0002065820.345
activation of cysteine type endopeptidase activityGO:0097202270.345
Human
positive regulation of mammary gland epithelial cell proliferationGO:003360150.344
positive regulation of lymphocyte activationGO:00512511400.344
Mouse
neural precursor cell proliferationGO:00613511210.343
regulation of hormone levelsGO:00108172110.343
angiogenesisGO:00015252010.341
taurine metabolic processGO:001953040.341
establishment of protein localization to organelleGO:00725941180.339
Mouse
actin filament bundle assemblyGO:0051017400.339
response to organic cyclic compoundGO:00140701980.338
positive regulation of myeloid cell apoptotic processGO:003303440.336
attachment of spindle microtubules to kinetochoreGO:000860840.334
positive regulation of proteolysisGO:0045862850.333
Human
leydig cell differentiationGO:0033327100.333
regulation of leukocyte proliferationGO:00706631210.332
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.332
organ growthGO:00352651170.332
female gamete generationGO:0007292740.331
response to steroid hormoneGO:0048545560.328
adaptive immune responseGO:00022501550.326
posttranscriptional regulation of gene expressionGO:00106081550.325
steroid hormone mediated signaling pathwayGO:004340160.324
regulation of microtubule polymerizationGO:003111370.323
smoothened signaling pathwayGO:00072241050.322
regulation of cellular response to insulin stimulusGO:1900076300.321
odontogenesisGO:0042476780.320
negative regulation of hydrolase activityGO:0051346710.318
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.317
negative regulation of mammary gland epithelial cell proliferationGO:003360030.315
response to iron ionGO:001003940.315
blastocyst growthGO:0001832230.313
mitotic sister chromatid cohesionGO:000706410.313
cellular response to oxidative stressGO:0034599760.310
negative regulation of oxidative stress induced cell deathGO:190320290.310
maintenance of apical basal cell polarityGO:003509030.309
activation of adenylate cyclase activityGO:000719040.309
tyrosine phosphorylation of stat3 proteinGO:0042503120.307
mapk cascadeGO:00001652810.307
dna repairGO:00062811070.306
regulation of neuron differentiationGO:00456642810.305
positive regulation of cyclin dependent protein serine threonine kinase activityGO:004573760.304
nucleoside triphosphate catabolic processGO:00091432050.304
mitotic g2 dna damage checkpointGO:000709580.304
defense response to bacteriumGO:00427421190.303
cell type specific apoptotic processGO:00972852680.302
positive regulation of cyclic nucleotide biosynthetic processGO:0030804240.302
purine ribonucleotide biosynthetic processGO:0009152590.298
oligodendrocyte differentiationGO:0048709530.298
regulation of mammary gland epithelial cell proliferationGO:0033599120.296

Cdkn1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system cancerDOID:006008300.994
cancerDOID:16200.994
disease of cellular proliferationDOID:1456600.994
organ system cancerDOID:005068600.994
hematologic cancerDOID:253100.982
bone marrow cancerDOID:496000.903
disease of metabolismDOID:001466700.878
urinary system cancerDOID:399600.550
disease of anatomical entityDOID:700.505
endocrine system diseaseDOID:2800.505
colon carcinomaDOID:152000.482
large intestine cancerDOID:567200.482
colon cancerDOID:21900.482
gastrointestinal system cancerDOID:311900.482
intestinal cancerDOID:1015500.482
colorectal cancerDOID:925600.482
diabetes mellitusDOID:935100.404
type 2 diabetes mellitusDOID:935200.404
carbohydrate metabolism diseaseDOID:005001300.404
glucose metabolism diseaseDOID:419400.404
acquired metabolic diseaseDOID:006015800.404
immune system diseaseDOID:291400.385
bone marrow diseaseDOID:496100.385
hematopoietic system diseaseDOID:7400.385
respiratory system cancerDOID:005061500.318
lung cancerDOID:132400.318