Mus musculus

217 known processes

Cdkn1a

cyclin-dependent kinase inhibitor 1A (P21)

(Aliases: Waf1,CIP1,CDKI,Cdkn1,CAP20,SDI1,P21,p21Cip1,mda6,p21WAF)

Cdkn1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
signal transduction involved in dna integrity checkpointGO:007240130.994
Human
regulation of kinase activityGO:00435492490.991
regulation of transferase activityGO:00513382630.989
activation of mapkkk activityGO:000018510.987
g1 s transition of mitotic cell cycleGO:0000082570.983
Human Mouse
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.980
cell cycle arrestGO:0007050370.973
negative regulation of protein phosphorylationGO:00019331260.965
regulation of cell cycleGO:00517262810.964
positive regulation of apoptotic processGO:00430652170.961
negative regulation of cellular protein metabolic processGO:00322692470.960
fibroblast proliferationGO:0048144350.952
Human
negative regulation of blood vessel endothelial cell migrationGO:004353730.943
negative regulation of fibroblast proliferationGO:0048147140.940
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.937
response to endoplasmic reticulum stressGO:0034976530.932
positive regulation of cell deathGO:00109422240.926
regulation of protein kinase activityGO:00458592320.912
gland developmentGO:00487323300.912
Mouse
negative regulation of leukocyte differentiationGO:1902106510.908
apoptotic process involved in mammary gland involutionGO:006005740.903
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.899
reactive oxygen species metabolic processGO:0072593840.895
negative regulation of molecular functionGO:00440922580.880
negative regulation of phosphatidylinositol 3 kinase activityGO:004355310.878
cellular response to radiationGO:0071478280.851
signal transduction involved in cell cycle checkpointGO:007239530.848
Human
negative regulation of protein modification processGO:00314001630.847
oocyte axis specificationGO:000730920.846
negative regulation of protein metabolic processGO:00512482820.839
cellular response to dna damage stimulusGO:00069742070.833
regulation of epithelial cell proliferationGO:00506781410.833
Mouse
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361880.829
positive regulation of cellular amino acid metabolic processGO:004576430.825
negative regulation of cell proliferationGO:00082852960.821
response to acid chemicalGO:00011011110.812
regulation of cellular amino acid metabolic processGO:000652150.810
blood vessel morphogenesisGO:00485142850.807
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.807
regulation of mitochondrial membrane permeabilityGO:0046902170.805
negative regulation of apoptotic signaling pathwayGO:20012341040.804
cation transportGO:00068123990.804
Mouse
signal transduction involved in dna damage checkpointGO:007242230.803
Human
sphingolipid metabolic processGO:0006665450.802
intracellular signal transduction involved in g1 dna damage checkpointGO:190240030.800
Human
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.797
mitotic cell cycleGO:00002781950.790
positive regulation of cardiac muscle cell apoptotic processGO:001066630.776
regulation of dna templated transcription in response to stressGO:004362090.773
muscle tissue developmentGO:00605373080.763
erythrocyte differentiationGO:0030218880.755
angiogenesisGO:00015252010.750
positive regulation of reactive oxygen species metabolic processGO:2000379110.737
germ cell developmentGO:00072811850.737
activation of mapkk activityGO:0000186150.727
response to oxidative stressGO:00069791230.722
mitotic g1 dna damage checkpointGO:003157140.716
Human
positive regulation of protein modification processGO:00314012990.712
Human
microtubule based processGO:00070172360.712
Mouse
positive regulation of protein phosphorylationGO:00019342420.710
Human
cellular response to inorganic substanceGO:0071241370.703
digestive tract developmentGO:00485651900.695
release of cytochrome c from mitochondriaGO:0001836230.691
cellular response to cytokine stimulusGO:00713451890.683
regionalizationGO:00030023370.683
cellular response to gamma radiationGO:007148040.682
response to radiationGO:00093141650.679
skeletal muscle organ developmentGO:00605381630.671
metanephric glomerular mesangium developmentGO:007222330.666
negative regulation of phosphorylationGO:00423261660.663
negative regulation of cellular amine metabolic processGO:003323910.657
signal transduction involved in mitotic dna damage checkpointGO:190240230.654
Human
positive regulation of neuron apoptotic processGO:0043525250.653
regulation of cell cycle processGO:00105641600.650
Human
regulation of cellular ketone metabolic processGO:0010565660.648
response to vitamin dGO:003328030.647
single organismal cell cell adhesionGO:00163371310.641
negative regulation of phosphate metabolic processGO:00459361840.641
response to ionizing radiationGO:0010212420.640
cellular response to x rayGO:007148120.639
cellular ketone metabolic processGO:0042180840.634
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.633
negative regulation of kinase activityGO:0033673810.630
mitochondrial dna repairGO:004350430.628
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.626
cellular response to oxidative stressGO:0034599760.620
nitric oxide mediated signal transductionGO:000726340.614
regulation of mitotic cell cycleGO:00073461260.614
establishment or maintenance of cytoskeleton polarityGO:003095220.612
apoptotic process involved in embryonic digit morphogenesisGO:190226330.610
positive regulation of glial cell proliferationGO:006025240.609
endothelial cell apoptotic processGO:007257790.609
negative regulation of oxidative stress induced cell deathGO:190320290.604
signal transduction involved in mitotic cell cycle checkpointGO:007241330.603
Human
regulation of somitogenesisGO:001480760.600
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.597
Human
pole plasm assemblyGO:000731520.596
urogenital system developmentGO:00016552610.595
Mouse
negative regulation of epithelial cell proliferationGO:0050680640.589
Mouse
positive regulation of protein serine threonine kinase activityGO:00719021060.586
positive regulation of mammary gland involutionGO:190352140.585
cellular amine metabolic processGO:0044106440.584
myeloid cell homeostasisGO:00022621140.582
mitotic cell cycle processGO:19030471590.577
Human Mouse
cellular amino acid metabolic processGO:00065201030.576
cellular response to metal ionGO:0071248310.573
placenta blood vessel developmentGO:0060674310.572
negative regulation of cellular amino acid metabolic processGO:004576300.571
mapk cascadeGO:00001652810.568
response to x rayGO:0010165110.568
regulation of response to oxidative stressGO:1902882190.565
digestive system developmentGO:00551232000.564
negative regulation of immune system processGO:00026832090.563
regulation of cellular amine metabolic processGO:0033238200.557
positive regulation of programmed cell deathGO:00430682180.557
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.554
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.553
positive regulation of striated muscle cell apoptotic processGO:001066330.547
homeostasis of number of cellsGO:00488722100.545
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.544
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.542
cerebral cortex developmentGO:0021987860.541
cellular response to external stimulusGO:0071496880.535
Human
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361920.534
regulation of fibroblast proliferationGO:0048145340.529
Human
lymphocyte differentiationGO:00300982420.520
response to hyperoxiaGO:005509320.519
myeloid cell differentiationGO:00300992330.516
striated muscle tissue developmentGO:00147062930.514
regulation of protein maturationGO:1903317960.508
amine metabolic processGO:0009308450.507
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108140.499
cellular response to growth factor stimulusGO:00713631970.499
negative regulation of lipid kinase activityGO:009021910.496
epithelial cell proliferationGO:00506731740.495
Mouse
ectopic germ cell programmed cell deathGO:003523490.495
regulation of cellular component biogenesisGO:00440871810.494
Mouse
kidney developmentGO:00018222130.493
negative regulation of intracellular signal transductionGO:19025321670.483
protein processingGO:00164851630.481
cell adhesionGO:00071553290.481
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.480
regulation of p38mapk cascadeGO:190074430.480
regulation of blood coagulationGO:0030193280.479
t cell activationGO:00421102890.475
regulation of protein serine threonine kinase activityGO:00719001570.473
positive regulation of protein kinase activityGO:00458601440.473
Human
negative regulation of lymphocyte apoptotic processGO:0070229240.471
positive regulation of p38mapk cascadeGO:190074510.470
pallium developmentGO:00215431200.469
protein modification by small protein conjugationGO:00324461870.469
positive regulation of cellular amine metabolic processGO:003324050.466
positive regulation of cell cycle phase transitionGO:1901989170.460
regulation of apoptotic signaling pathwayGO:20012331970.460
positive regulation of cell cycle g1 s phase transitionGO:190280890.460
skeletal system developmentGO:00015013560.459
wound healingGO:00420601570.457
regulation of cell cycle phase transitionGO:1901987770.453
Human
response to nutrient levelsGO:00316671090.451
response to inorganic substanceGO:0010035960.447
response to amino acidGO:0043200370.442
protein modification by small protein conjugation or removalGO:00706472070.442
negative regulation of endothelial cell migrationGO:001059640.442
positive regulation of apoptotic process involved in morphogenesisGO:190233940.441
intrinsic apoptotic signaling pathwayGO:00971931320.439
mammary gland epithelial cell proliferationGO:0033598240.433
labyrinthine layer developmentGO:0060711490.433
regulation of lymphocyte activationGO:00512492400.432
negative regulation of ubiquitin protein transferase activityGO:005144430.428
regulation of mapk cascadeGO:00434082480.428
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217590.427
cell cycle g1 s phase transitionGO:0044843570.413
Human Mouse
regulation of leukocyte differentiationGO:19021051590.413
negative regulation of phosphorus metabolic processGO:00105631840.413
regulation of endothelial cell apoptotic processGO:200035190.401
response to hypoxiaGO:0001666580.400
apoptotic mitochondrial changesGO:0008637480.398
positive regulation of leukocyte differentiationGO:1902107860.396
microtubule cytoskeleton organizationGO:00002261570.396
Mouse
regulation of peptidase activityGO:0052547960.395
modulation by virus of host morphology or physiologyGO:001904830.394
spermatid differentiationGO:00485151150.394
positive regulation of angiogenesisGO:0045766460.385
positive regulation of lymphocyte apoptotic processGO:0070230130.384
t cell selectionGO:0045058340.384
negative regulation of proteolysisGO:0045861740.384
positive regulation of cell cycleGO:0045787920.381
Human
positive regulation of protein oligomerizationGO:003246140.378
negative regulation of map kinase activityGO:0043407340.372
cellular lipid metabolic processGO:00442553230.370
oocyte differentiationGO:0009994350.369
response to vitamin aGO:003318910.367
embryonic placenta developmentGO:0001892980.366
mitochondrial membrane organizationGO:0007006260.363
keratinocyte migrationGO:005154630.359
cell growthGO:00160491300.358
Human
developmental maturationGO:00217001930.358
protein maturationGO:00516041760.357
positive regulation of cell developmentGO:00107202370.356
epithelial cell differentiation involved in prostate gland developmentGO:0060742130.356
negative regulation of protein serine threonine kinase activityGO:0071901490.356
modification dependent macromolecule catabolic processGO:00436321330.356
positive regulation of mitotic cell cycle phase transitionGO:1901992170.354
renal system developmentGO:00720012250.351
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337630.348
regulation of cell activationGO:00508652890.348
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.346
negative regulation of protein processingGO:0010955790.346
protein ubiquitinationGO:00165671710.343
regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006141820.343
positive regulation of mitochondrial membrane permeabilityGO:0035794120.340
cellular response to decreased oxygen levelsGO:0036294180.339
tissue remodelingGO:00487711020.339
negative regulation of syncytium formation by plasma membrane fusionGO:003424250.336
regulation of endopeptidase activityGO:0052548890.335
negative regulation of hydrolase activityGO:0051346710.333
t cell differentiationGO:00302171740.329
divalent inorganic cation homeostasisGO:00725071380.326
response to uvGO:0009411440.324
sprouting angiogenesisGO:0002040260.324
negative regulation of cellular response to oxidative stressGO:1900408100.324
extrinsic apoptotic signaling pathwayGO:00971911260.323
glomerulus developmentGO:0032835400.323
regulation of blood vessel remodelingGO:006031230.322
negative regulation of response to oxidative stressGO:1902883100.320
jnk cascadeGO:0007254720.315
oocyte constructionGO:000730820.313
centrosome organizationGO:0051297260.311
forebrain developmentGO:00309003020.307
mammary gland epithelium developmentGO:0061180650.306
hair follicle morphogenesisGO:0031069290.304
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.304
leukocyte differentiationGO:00025213420.304
b cell activationGO:00421131610.303
negative regulation of protein maturationGO:1903318790.301
positive regulation of protein complex assemblyGO:0031334450.300
Mouse
negative regulation of cell cycle arrestGO:007115710.300
negative regulation of photoreceptor cell differentiationGO:004653340.295
segmentationGO:0035282930.295
response to extracellular stimulusGO:00099911270.294
Human
response to oxygen levelsGO:0070482620.289
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.288
zymogen activationGO:0031638410.287
protein catabolic processGO:00301632210.287
response to chromateGO:004668710.285
lymphocyte homeostasisGO:0002260640.285
glial cell apoptotic processGO:003434930.282
regulation of cellular response to stressGO:00801351590.282
multi multicellular organism processGO:00447061090.281
female genitalia morphogenesisGO:004880730.280
negative regulation of cell cycleGO:00457861230.279
negative regulation of transferase activityGO:0051348850.279
odontogenesisGO:0042476780.278
actin filament organizationGO:00070151130.278
regulation of b cell activationGO:0050864810.276
ras protein signal transductionGO:0007265770.276
Human
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.275
positive regulation of mitotic cell cycleGO:0045931410.274
regulation of cellular response to oxidative stressGO:1900407190.274
positive regulation of histone modificationGO:0031058280.274
sensory organ morphogenesisGO:00905962420.272
regulation of mitotic cell cycle phase transitionGO:1901990730.272
Human
proteolysis involved in cellular protein catabolic processGO:00516031470.272
regulation of neuron differentiationGO:00456642810.272
mitotic cell cycle arrestGO:007185040.272
response to lithium ionGO:0010226100.271
positive regulation of cell cycle processGO:0090068610.270
Human
response to organophosphorusGO:0046683220.269
plasma membrane long chain fatty acid transportGO:001591110.262
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.261
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.258
negative regulation of glial cell proliferationGO:006025340.258
pharynx developmentGO:006046510.257
morphogenesis of a branching epitheliumGO:00611381930.256
cell chemotaxisGO:0060326810.253
negative regulation of lipid metabolic processGO:0045833300.250
regulation of protein processingGO:0070613960.250
dendrite developmentGO:00163581150.248
positive regulation of mapk cascadeGO:00434101700.248
mitochondrion degradationGO:000042230.247
appendage morphogenesisGO:00351071490.244
regulation of epidermal cell divisionGO:001048230.243
response to growth factorGO:00708481980.240
negative regulation of dendritic spine developmentGO:006100030.240
mitotic sister chromatid cohesionGO:000706410.240
peptidyl amino acid modificationGO:00181933360.238
regulation of wound healingGO:0061041400.237
cellular response to abiotic stimulusGO:0071214560.235
microtubule depolymerizationGO:0007019150.234
regulation of protein stabilityGO:0031647520.232
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.230
regulation of tissue remodelingGO:0034103380.229
neuronal action potentialGO:0019228540.226
cellular response to extracellular stimulusGO:0031668810.226
Human
negative regulation of cellular protein catabolic processGO:1903363220.225
calcium ion transportGO:00068161590.225
regulation of mammary gland involutionGO:190351940.223
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.223
signal transduction by p53 class mediatorGO:0072331510.223
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225520.221
positive regulation of cytokine productionGO:00018191740.219
cellular response to prostaglandin stimulusGO:007137920.218
positive regulation of muscle cell apoptotic processGO:001066160.218
negative regulation of cell migrationGO:0030336590.216
regulation of leukocyte apoptotic processGO:2000106560.216
response to decreased oxygen levelsGO:0036293590.215
macrophage differentiationGO:0030225200.215
leukocyte apoptotic processGO:0071887710.210
stem cell maintenanceGO:00198271300.210
face morphogenesisGO:0060325290.210
purine ribonucleotide metabolic processGO:00091502900.210
positive regulation of map kinase activityGO:0043406840.210
peptidyl tyrosine phosphorylationGO:00181081430.209
female gamete generationGO:0007292740.208
neuroblast fate determinationGO:000740010.207
dna metabolic processGO:00062593030.206
regulation of proteolysisGO:00301621640.205
cell type specific apoptotic processGO:00972852680.205
negative regulation of transcription from rna polymerase ii promoter in response to stressGO:009720110.204
response to light stimulusGO:00094161350.204
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.204
notch signaling pathwayGO:0007219710.204
regulation of fibrinolysisGO:005191710.203
regulation of organelle organizationGO:00330432890.202
Mouse
engulfment of apoptotic cellGO:004365230.202
regulation of protein targetingGO:1903533610.202
b cell apoptotic processGO:0001783190.201
positive regulation of protein acetylationGO:190198590.201
regulation of anoikisGO:200020920.200
negative regulation of cell motilityGO:2000146610.199
regulation of lymphocyte differentiationGO:00456191070.198
axonogenesisGO:00074092740.198
positive regulation of osteoclast differentiationGO:0045672150.196
regulation of hydrolase activityGO:00513362460.194
blood vessel endothelial cell migrationGO:0043534230.194
nuclear divisionGO:00002801580.194
regulation of cellular response to growth factor stimulusGO:0090287820.194
organ growthGO:00352651170.193
cellular response to ionizing radiationGO:0071479110.193
regulation of endothelial cell chemotaxisGO:200102610.192
positive regulation of myeloid leukocyte differentiationGO:0002763260.192
proteasomal protein catabolic processGO:0010498980.191
neuron apoptotic processGO:00514021420.191
apoptotic signaling pathwayGO:00971903060.191
peptidyl tyrosine modificationGO:00182121450.190
positive regulation of epithelial cell proliferationGO:0050679680.190
posttranscriptional regulation of gene expressionGO:00106081550.190
branching morphogenesis of an epithelial tubeGO:00487541590.189
regulation of cytoskeleton organizationGO:00514931220.188
Mouse
myeloid cell apoptotic processGO:0033028220.188
negative regulation of cell growthGO:0030308440.188
Human
limb developmentGO:00601731660.185
carbohydrate metabolic processGO:00059752300.185
modification dependent protein catabolic processGO:00199411330.183
regulation of lymphocyte proliferationGO:00506701170.182
fibroblast growth factor receptor signaling pathwayGO:0008543460.181
appendage developmentGO:00487361660.180
regulation of membrane permeabilityGO:0090559180.180
regulation of t cell differentiationGO:0045580830.180
prostate gland developmentGO:0030850480.180
Mouse
circulatory system processGO:00030131970.179
platelet derived growth factor receptor alpha signaling pathwayGO:003579030.179
response to peptideGO:19016521360.177
growth involved in heart morphogenesisGO:000324140.176
regulation of transmembrane transportGO:00347621280.176
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.175
actin filament bundle assemblyGO:0051017400.175
myeloid leukocyte activationGO:0002274830.174
positive t cell selectionGO:0043368230.174
liposaccharide metabolic processGO:1903509270.174
regulation of cell cycle g1 s phase transitionGO:1902806350.173
Human
regulation of vasculature developmentGO:1901342880.172
response to ischemiaGO:0002931140.172
cytokine productionGO:00018163190.171
cellular protein catabolic processGO:00442571550.170
positive regulation of mitotic sister chromatid separationGO:190197020.167
cell death in response to oxidative stressGO:0036473240.166
cellular response to amino acid stimulusGO:0071230290.166
negative regulation of endopeptidase activityGO:0010951440.165
p38mapk cascadeGO:003806640.165
regulation of stress activated mapk cascadeGO:0032872690.165
liver developmentGO:0001889660.164
regulation of hemostasisGO:1900046280.164
negative regulation of keratinocyte differentiationGO:004561740.163
glycolipid metabolic processGO:0006664250.163
modification by symbiont of host morphology or physiologyGO:004400340.162
glomerular capillary formationGO:007210460.162
regulation of cellular response to hypoxiaGO:190003720.161
cellular chemical homeostasisGO:00550822150.161
cgmp mediated signalingGO:001993430.161
negative regulation of cell activationGO:00508661110.160
positive regulation of nervous system developmentGO:00519622210.159
endothelial cell proliferationGO:0001935270.159
positive regulation of mitochondrion organizationGO:0010822170.159
carbohydrate derivative biosynthetic processGO:19011371830.159
response to tumor necrosis factorGO:0034612260.157
negative regulation of cellular component organizationGO:00511291940.156
epidermis developmentGO:00085441870.156
cell migration involved in endocardial cushion formationGO:000327330.155
membrane organizationGO:00610242450.155
stress response to metal ionGO:009750130.155
regulation of b cell differentiationGO:0045577230.155
telencephalon developmentGO:00215371860.154
regulation of angiogenesisGO:0045765810.153
hypoxia inducible factor 1alpha signaling pathwayGO:009741120.152
positive regulation of apoptotic signaling pathwayGO:2001235950.151
hippocampus developmentGO:0021766520.151
response to hydrogen peroxideGO:0042542320.151
cellular response to acid chemicalGO:0071229680.151
morphogenesis of a branching structureGO:00017632030.151
traversing start control point of mitotic cell cycleGO:000708920.150
negative regulation of peptidase activityGO:0010466460.150
regulation of myeloid leukocyte differentiationGO:0002761580.149
dephosphorylationGO:00163111290.146
maternal determination of anterior posterior axis embryoGO:000835820.146
negative regulation of lymphocyte differentiationGO:0045620320.145
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697820.145
response to corticosteroneGO:005141210.145
placenta developmentGO:00018901400.144
negative regulation of anoikisGO:200081120.144
renal system vasculature morphogenesisGO:006143870.144
negative regulation of neuron apoptotic processGO:0043524920.143
response to corticosteroidGO:0031960200.142
regulation of lipid kinase activityGO:0043550140.142
regulation of body fluid levelsGO:00508781620.142
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathwayGO:003579310.142
response to drugGO:0042493750.141
receptor biosynthetic processGO:003280030.141
mitochondrial transportGO:0006839360.141
neuroblast differentiationGO:001401620.140
epithelial tube morphogenesisGO:00605623030.140
positive regulation of cell motilityGO:20001471160.140
negative regulation of mitotic cell cycle phase transitionGO:1901991450.140
Human
embryonic limb morphogenesisGO:00303261260.139
skin developmentGO:00435882200.139
establishment or maintenance of cell polarityGO:0007163860.138
dna replicationGO:0006260520.138
multicellular organismal metabolic processGO:0044236280.138
cellular response to hypoxiaGO:0071456170.138
epidermis morphogenesisGO:0048730330.137
positive regulation of keratinocyte differentiationGO:004561830.136
ubiquitin dependent protein catabolic processGO:00065111290.135
digestive tract morphogenesisGO:00485461470.134
neutrophil apoptotic processGO:000178130.134
cell cycle checkpointGO:0000075470.134
Human
carbohydrate homeostasisGO:00335001280.133
dendritic spine maintenanceGO:009706240.133
hematopoietic progenitor cell differentiationGO:00022441430.132
b cell lineage commitmentGO:000232640.132
meiotic cell cycleGO:00513211220.132
lymphocyte proliferationGO:00466511640.131
regulation of ion transportGO:00432692150.131
regulation of developmental pigmentationGO:0048070140.131
tissue migrationGO:0090130680.130
leukocyte homeostasisGO:0001776790.129
regulation of ubiquitin protein transferase activityGO:005143870.128
inflammatory responseGO:00069542440.128
actin cytoskeleton organizationGO:00300362200.127
signal transduction involved in mitotic g1 dna damage checkpointGO:007243130.127
Human
oocyte developmentGO:0048599330.127
purine nucleotide metabolic processGO:00061633020.127
response to reactive oxygen speciesGO:0000302560.126
smooth muscle tissue developmentGO:0048745220.125
microtubule organizing center organizationGO:0031023280.125
regulation of coagulationGO:0050818310.124
organelle fissionGO:00482851700.124
b cell differentiationGO:0030183780.123
rrna transcriptionGO:000930390.123
regulation of notch signaling pathwayGO:0008593350.123
positive regulation of organelle organizationGO:00106381280.122
Mouse
activation of cysteine type endopeptidase activityGO:0097202270.122
cytokine mediated signaling pathwayGO:00192211150.121
regulation of g1 s transition of mitotic cell cycleGO:2000045350.121
Human
cloacal septationGO:006019720.120
positive regulation of coagulationGO:0050820130.120
response to starvationGO:0042594650.120
response to increased oxygen levelsGO:003629620.120
protein localization to organelleGO:00333651850.120
regulation of epidermal cell differentiationGO:0045604210.120
long chain fatty acid transportGO:0015909150.119
single organism nuclear importGO:1902593950.119
photoreceptor cell differentiationGO:0046530520.119

Cdkn1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.957
cancerDOID:16200.783
organ system cancerDOID:005068600.665
disease of anatomical entityDOID:700.277
musculoskeletal system diseaseDOID:1700.277
connective tissue diseaseDOID:6500.277
immune system diseaseDOID:291400.210
immune system cancerDOID:006008300.208
gastrointestinal system cancerDOID:311900.203
urinary system cancerDOID:399600.197
endocrine gland cancerDOID:17000.195
hematopoietic system diseaseDOID:7400.146
kidney cancerDOID:26300.119