Mus musculus

60 known processes

Smek1

SMEK homolog 1, suppressor of mek1 (Dictyostelium)

(Aliases: BC064465,1110034C04Rik,mKIAA2010)

Smek1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
male gamete generationGO:00482322850.056
cellular macromolecule catabolic processGO:00442652060.042
mrna processingGO:0006397630.040
mrna metabolic processGO:0016071840.040
rna processingGO:00063961050.040
histone modificationGO:00165701590.037
covalent chromatin modificationGO:00165691630.036
heterocycle catabolic processGO:00467002800.035
macromolecule catabolic processGO:00090572810.033
regulation of organelle organizationGO:00330432890.032
positive regulation of cellular amino acid metabolic processGO:004576430.029
spermatogenesisGO:00072832840.028
cellular amino acid metabolic processGO:00065201030.027
cellular amine metabolic processGO:0044106440.027
regulation of membrane potentialGO:00423911920.027
cellular nitrogen compound catabolic processGO:00442702800.026
regulation of cellular ketone metabolic processGO:0010565660.026
chromatin organizationGO:00063252060.025
positive regulation of apoptotic processGO:00430652170.025
chromatin modificationGO:00165681870.025
mitotic cell cycleGO:00002781950.024
nuclear divisionGO:00002801580.024
regulation of cellular amino acid metabolic processGO:000652150.024
negative regulation of cellular component organizationGO:00511291940.023
modification dependent macromolecule catabolic processGO:00436321330.023
regulation of cellular amine metabolic processGO:0033238200.023
regulation of neuron differentiationGO:00456642810.022
ubiquitin dependent protein catabolic processGO:00065111290.021
inflammatory responseGO:00069542440.021
proteolysis involved in cellular protein catabolic processGO:00516031470.021
positive regulation of cellular amine metabolic processGO:003324050.021
protein catabolic processGO:00301632210.021
organelle fissionGO:00482851700.021
aromatic compound catabolic processGO:00194392860.021
organic cyclic compound catabolic processGO:19013612950.020
cellular response to dna damage stimulusGO:00069742070.020
nitrogen compound transportGO:00717052710.020
dna metabolic processGO:00062593030.020
posttranscriptional regulation of gene expressionGO:00106081550.020
ribose phosphate metabolic processGO:00196932910.020
protein maturationGO:00516041760.020
cation transportGO:00068123990.020
cell type specific apoptotic processGO:00972852680.019
mitotic cell cycle processGO:19030471590.019
membrane organizationGO:00610242450.019
negative regulation of protein metabolic processGO:00512482820.018
mrna splicing via spliceosomeGO:0000398430.018
spermatid differentiationGO:00485151150.018
amine metabolic processGO:0009308450.018
sensory perceptionGO:00076002450.018
leukocyte differentiationGO:00025213420.018
germ cell developmentGO:00072811850.018
modification dependent protein catabolic processGO:00199411330.018
regulation of cellular catabolic processGO:00313292420.018
spermatid developmentGO:00072861080.018
cytokine productionGO:00018163190.018
transmembrane transportGO:00550854120.017
reactive oxygen species metabolic processGO:0072593840.017
rna splicing via transesterification reactionsGO:0000375430.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
cellular homeostasisGO:00197252400.017
nucleobase containing small molecule metabolic processGO:00550863520.017
mitochondrion organizationGO:00070051340.017
negative regulation of immune system processGO:00026832090.017
regulation of mrna metabolic processGO:1903311430.017
homeostasis of number of cellsGO:00488722100.017
response to organonitrogen compoundGO:00102432460.017
lymphocyte differentiationGO:00300982420.016
positive regulation of nervous system developmentGO:00519622210.016
rna splicingGO:0008380540.016
peptidyl amino acid modificationGO:00181933360.016
positive regulation of cell developmentGO:00107202370.016
purine ribonucleotide metabolic processGO:00091502900.016
cellular protein complex assemblyGO:00436231160.016
cellular ketone metabolic processGO:0042180840.016
protein modification by small protein conjugationGO:00324461870.016
positive regulation of cell deathGO:00109422240.016
regulation of cell activationGO:00508652890.016
regulation of cell projection organizationGO:00313442060.016
regulation of neuron projection developmentGO:00109751690.016
multicellular organismal homeostasisGO:00488711640.016
regulation of apoptotic signaling pathwayGO:20012331970.016
action potentialGO:0001508780.015
glycosyl compound metabolic processGO:19016572460.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
regulation of mrna processingGO:0050684410.015
regulation of anatomical structure sizeGO:00900661780.015
positive regulation of programmed cell deathGO:00430682180.015
engulfment of apoptotic cellGO:004365230.015
regulation of cellular component biogenesisGO:00440871810.015
negative regulation of cellular protein metabolic processGO:00322692470.015
negative regulation of molecular functionGO:00440922580.015
cellular chemical homeostasisGO:00550822150.015
nucleoside phosphate metabolic processGO:00067533380.015
regulation of secretionGO:00510462740.015
oocyte axis specificationGO:000730920.015
mapk cascadeGO:00001652810.015
regulation of protein localizationGO:00328802310.015
dna repairGO:00062811070.015
cellular response to organonitrogen compoundGO:00714171450.015
regulation of cell cycleGO:00517262810.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.015
regulation of cell cycle processGO:00105641600.015
synaptic transmissionGO:00072683290.014
embryonic epithelial tube formationGO:00018381300.014
epithelial tube formationGO:00721751300.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
regulation of translationGO:0006417710.014
regulation of lymphocyte activationGO:00512492400.014
cellular lipid metabolic processGO:00442553230.014
nucleotide metabolic processGO:00091173320.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.014
apoptotic signaling pathwayGO:00971903060.014
t cell activationGO:00421102890.014
b cell activationGO:00421131610.014
cellular protein catabolic processGO:00442571550.014
purine containing compound catabolic processGO:00725232130.014
small gtpase mediated signal transductionGO:0007264970.014
epithelial tube morphogenesisGO:00605623030.014
endomembrane system organizationGO:00102561470.014
cellular response to hormone stimulusGO:00328701500.014
gland developmentGO:00487323300.014
negative regulation of cellular amino acid metabolic processGO:004576300.013
purine nucleoside metabolic processGO:00422782410.013
tube formationGO:00351481400.013
regulation of cellular component sizeGO:00325351210.013
response to light stimulusGO:00094161350.013
ribonucleoside metabolic processGO:00091192450.013
purine containing compound metabolic processGO:00725213110.013
regulation of mapk cascadeGO:00434082480.013
axonogenesisGO:00074092740.013
oxidation reduction processGO:00551143420.013
stem cell developmentGO:00488642190.013
regulation of mrna splicing via spliceosomeGO:0048024320.013
cytoplasmic transportGO:00164822340.013
methylationGO:00322591340.013
negative regulation of nervous system developmentGO:00519611560.013
cation homeostasisGO:00550802120.013
translationGO:0006412930.013
organelle localizationGO:00516401790.013
protein methylationGO:0006479810.013
regulation of hormone levelsGO:00108172110.013
regulation of cytokine productionGO:00018172660.013
organophosphate catabolic processGO:00464342320.013
neural tube formationGO:00018411080.013
meiotic cell cycleGO:00513211220.013
transmission of nerve impulseGO:0019226760.013
compound eye developmentGO:004874910.013
anatomical structure homeostasisGO:00602491450.013
purine nucleoside triphosphate catabolic processGO:00091462030.012
neural tube closureGO:0001843900.012
purine ribonucleoside catabolic processGO:00461302050.012
nucleoside catabolic processGO:00091642060.012
negative regulation of organelle organizationGO:0010639900.012
protein ubiquitinationGO:00165671710.012
nucleoside triphosphate metabolic processGO:00091412300.012
endocytosisGO:00068971680.012
morphogenesis of embryonic epitheliumGO:00163311590.012
amide transportGO:00428861380.012
regulation of secretion by cellGO:19035302490.012
tube closureGO:0060606910.012
regulation of proteolysisGO:00301621640.012
nucleocytoplasmic transportGO:00069131390.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
nucleoside triphosphate catabolic processGO:00091432050.012
blastocyst developmentGO:0001824800.012
regulation of defense responseGO:00313472330.012
primary neural tube formationGO:0014020950.012
rhythmic processGO:00485111740.012
cation transmembrane transportGO:00986552660.012
purine nucleoside catabolic processGO:00061522050.012
regulation of inflammatory responseGO:00507271470.012
ribonucleotide metabolic processGO:00092592910.012
adaptive immune responseGO:00022501550.012
nucleotide catabolic processGO:00091662170.012
multicellular organismal signalingGO:0035637910.012
microtubule based processGO:00070172360.012
response to organic cyclic compoundGO:00140701980.012
mitotic nuclear divisionGO:0007067480.012
muscle cell differentiationGO:00426922610.012
oocyte constructionGO:000730820.011
purine ribonucleotide catabolic processGO:00091542080.011
neural tube developmentGO:00219151600.011
tissue homeostasisGO:00018941150.011
nucleoside metabolic processGO:00091162460.011
regulation of leukocyte differentiationGO:19021051590.011
multicellular organism growthGO:00352641610.011
regulation of response to woundingGO:19030341890.011
positive regulation of neuron differentiationGO:00456661410.011
ribonucleotide catabolic processGO:00092612080.011
purine nucleotide catabolic processGO:00061952110.011
response to radiationGO:00093141650.011
maintenance of locationGO:0051235890.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
neuron apoptotic processGO:00514021420.011
fertilizationGO:00095661270.011
circadian regulation of gene expressionGO:0032922480.011
cell adhesionGO:00071553290.011
nuclear transportGO:00511691390.011
neuron deathGO:00709971540.011
cellularizationGO:000734910.011
regulation of wnt signaling pathwayGO:00301111230.011
ras protein signal transductionGO:0007265770.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
establishment of organelle localizationGO:00516561220.011
positive regulation of organelle organizationGO:00106381280.011
regulation of protein kinase activityGO:00458592320.011
regionalizationGO:00030023370.011
myeloid cell differentiationGO:00300992330.011
regulation of cell migrationGO:00303342190.011
purine ribonucleoside metabolic processGO:00461282410.011
microtubule cytoskeleton organizationGO:00002261570.011
forebrain developmentGO:00309003020.011
meiotic nuclear divisionGO:00071261150.011
chromosome segregationGO:0007059480.011
female gamete generationGO:0007292740.010
proteasomal protein catabolic processGO:0010498980.010
muscle tissue developmentGO:00605373080.010
cellular ion homeostasisGO:00068731650.010
rna interferenceGO:001624620.010
response to lipopolysaccharideGO:00324961280.010
neuronal action potentialGO:0019228540.010
nucleic acid phosphodiester bond hydrolysisGO:0090305490.010
lung developmentGO:00303241640.010
regulation of homeostatic processGO:00328441820.010
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
respiratory tube developmentGO:00303231670.010
lipid biosynthetic processGO:00086101790.010
cell divisionGO:00513011200.010
positive regulation of cell projection organizationGO:0031346950.010
response to acid chemicalGO:00011011110.010
cellular response to peptide hormone stimulusGO:0071375920.010
regulation of protein serine threonine kinase activityGO:00719001570.010
regulation of neuron apoptotic processGO:00435231220.010

Smek1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.013
central nervous system diseaseDOID:33100.011