Mus musculus

60 known processes

Smek2

SMEK homolog 2, suppressor of mek1 (Dictyostelium)

(Aliases: KIAA1387,AW557776,AW011752,mKIAA1387)

Smek2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine ribonucleoside catabolic processGO:00461302050.166
organic cyclic compound catabolic processGO:19013612950.142
ribonucleoside triphosphate catabolic processGO:00092031990.127
mitotic cell cycleGO:00002781950.122
aromatic compound catabolic processGO:00194392860.103
cellular response to dna damage stimulusGO:00069742070.098
ribose phosphate metabolic processGO:00196932910.091
nucleotide metabolic processGO:00091173320.091
regulation of cell cycle processGO:00105641600.090
ras protein signal transductionGO:0007265770.086
dna metabolic processGO:00062593030.085
chromatin organizationGO:00063252060.079
regulation of organelle organizationGO:00330432890.079
genetic imprintingGO:0071514270.075
gene silencing by rnaGO:0031047190.067
cellular nitrogen compound catabolic processGO:00442702800.063
positive regulation of protein modification processGO:00314012990.061
carbohydrate derivative catabolic processGO:19011362310.058
regulation of cellular ketone metabolic processGO:0010565660.057
neural tube developmentGO:00219151600.055
purine ribonucleotide catabolic processGO:00091542080.055
posttranscriptional gene silencingGO:0016441100.052
positive regulation of cell cycle processGO:0090068610.048
organelle fissionGO:00482851700.047
nucleobase containing small molecule metabolic processGO:00550863520.047
apical constrictionGO:000338340.047
rna interferenceGO:001624620.047
cellular amino acid metabolic processGO:00065201030.047
heterocycle catabolic processGO:00467002800.046
regulation of chromosome organizationGO:0033044830.046
negative regulation of molecular functionGO:00440922580.046
chromatin modificationGO:00165681870.045
histone modificationGO:00165701590.045
nucleoside phosphate metabolic processGO:00067533380.045
myeloid cell differentiationGO:00300992330.043
histone lysine methylationGO:0034968500.043
erythrocyte differentiationGO:0030218880.043
purine containing compound metabolic processGO:00725213110.043
purine ribonucleoside triphosphate catabolic processGO:00092071990.042
rna processingGO:00063961050.042
nuclear divisionGO:00002801580.041
purine containing compound catabolic processGO:00725232130.041
ribonucleotide catabolic processGO:00092612080.040
organophosphate catabolic processGO:00464342320.040
macromolecule methylationGO:00434141200.039
cell divisionGO:00513011200.038
purine nucleoside triphosphate metabolic processGO:00091442260.037
cellular ketone metabolic processGO:0042180840.036
protein polymerizationGO:0051258570.036
purine ribonucleoside metabolic processGO:00461282410.036
cell type specific apoptotic processGO:00972852680.036
methylationGO:00322591340.036
positive regulation of cellular amine metabolic processGO:003324050.036
bone developmentGO:00603481200.035
vacuole organizationGO:0007033380.035
organonitrogen compound catabolic processGO:19015652640.035
regulation of chromatin modificationGO:1903308570.034
nucleoside phosphate catabolic processGO:19012922220.034
mitotic nuclear divisionGO:0007067480.034
ribonucleoside catabolic processGO:00424542060.034
ribonucleoside triphosphate metabolic processGO:00091992200.034
nucleoside triphosphate catabolic processGO:00091432050.034
regulation of protein complex assemblyGO:0043254830.033
germ cell developmentGO:00072811850.033
regulation of nucleotide metabolic processGO:00061401690.033
cell cycle checkpointGO:0000075470.032
ossificationGO:00015032160.031
development of primary sexual characteristicsGO:00451371430.031
purine ribonucleotide metabolic processGO:00091502900.030
purine nucleoside triphosphate catabolic processGO:00091462030.030
blastocyst developmentGO:0001824800.029
positive regulation of protein phosphorylationGO:00019342420.029
cellular response to radiationGO:0071478280.029
ribonucleoside metabolic processGO:00091192450.029
mrna metabolic processGO:0016071840.028
glycosyl compound metabolic processGO:19016572460.028
regulation of nucleoside metabolic processGO:00091181300.027
epithelial cell developmentGO:00020641590.027
nucleotide catabolic processGO:00091662170.027
meiotic cell cycle processGO:1903046770.027
negative regulation of mitotic cell cycle phase transitionGO:1901991450.027
regulation of cell cycleGO:00517262810.026
uterus morphogenesisGO:006103820.026
mitotic cell cycle processGO:19030471590.026
response to radiationGO:00093141650.026
nucleoside metabolic processGO:00091162460.026
small gtpase mediated signal transductionGO:0007264970.025
positive regulation of cell cycleGO:0045787920.025
rho protein signal transductionGO:0007266320.025
ribonucleotide metabolic processGO:00092592910.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
negative regulation of immune system processGO:00026832090.024
regulation of cell motilityGO:20001452360.024
neural tube formationGO:00018411080.024
regulation of cellular catabolic processGO:00313292420.024
gene silencingGO:0016458380.023
nucleoside catabolic processGO:00091642060.023
purine nucleotide catabolic processGO:00061952110.023
regulation of transcription by chromatin organizationGO:003440100.023
microtubule cytoskeleton organizationGO:00002261570.023
nucleoside monophosphate metabolic processGO:0009123850.023
posttranscriptional regulation of gene expressionGO:00106081550.022
negative regulation of cell cycleGO:00457861230.022
microtubule based processGO:00070172360.021
purine nucleoside metabolic processGO:00422782410.021
purine nucleoside catabolic processGO:00061522050.021
stem cell developmentGO:00488642190.021
rna splicingGO:0008380540.021
regulation of chromatin organizationGO:1902275570.021
positive regulation of protein kinase activityGO:00458601440.020
retina development in camera type eyeGO:00600411190.020
chromosome segregationGO:0007059480.020
regulation of mitotic cell cycle phase transitionGO:1901990730.020
regulation of feeding behaviorGO:006025930.020
gland developmentGO:00487323300.019
cell matrix adhesionGO:0007160680.019
protein modification by small protein conjugationGO:00324461870.019
organelle assemblyGO:00709251770.019
skeletal system developmentGO:00015013560.019
nucleoside triphosphate metabolic processGO:00091412300.019
neuron apoptotic processGO:00514021420.019
regulation of meiotic cell cycleGO:0051445340.019
positive regulation of apoptotic processGO:00430652170.018
locomotory behaviorGO:00076261950.018
regulation of mapk cascadeGO:00434082480.018
peptidyl amino acid modificationGO:00181933360.018
meiotic cell cycleGO:00513211220.018
appendage developmentGO:00487361660.018
regulation of neuron projection developmentGO:00109751690.018
heart morphogenesisGO:00030071780.018
cellular response to abiotic stimulusGO:0071214560.018
ribonucleoside monophosphate catabolic processGO:0009158570.017
amine metabolic processGO:0009308450.017
angiogenesisGO:00015252010.017
endocytosisGO:00068971680.017
atp catabolic processGO:0006200550.017
termination of rna polymerase i transcriptionGO:000636320.017
regulation of nucleotide catabolic processGO:00308111220.017
circulatory system processGO:00030131970.017
histone h3 k9 trimethylationGO:003612460.016
positive regulation of kinase activityGO:00336741550.016
regulation of cell substrate adhesionGO:0010810730.016
purine ribonucleoside monophosphate metabolic processGO:0009167800.016
dna repairGO:00062811070.016
oxidation reduction processGO:00551143420.016
divalent inorganic cation homeostasisGO:00725071380.016
chromatin silencing at rdnaGO:000018330.016
homeostasis of number of cellsGO:00488722100.016
regulation of apoptotic signaling pathwayGO:20012331970.016
positive regulation of gtpase activityGO:0043547850.016
histone h4 k20 trimethylationGO:003477320.016
positive regulation of transferase activityGO:00513471670.016
blood circulationGO:00080151950.016
regulation of cellular amino acid metabolic processGO:000652150.015
regulation of transferase activityGO:00513382630.015
fat cell differentiationGO:00454441600.015
cellular response to lipidGO:00713961450.015
regulation of hydrolase activityGO:00513362460.015
negative regulation of phosphate metabolic processGO:00459361840.015
regulation of cell migrationGO:00303342190.015
establishment or maintenance of polarity of embryonic epitheliumGO:001633210.015
spermatogenesisGO:00072832840.015
protein autophosphorylationGO:0046777610.015
necrotic cell deathGO:0070265300.015
regulation of cellular component biogenesisGO:00440871810.015
bone morphogenesisGO:0060349780.015
purine nucleotide metabolic processGO:00061633020.015
response to growth factorGO:00708481980.014
regulation of cell activationGO:00508652890.014
sensory organ morphogenesisGO:00905962420.014
regulation of cell projection organizationGO:00313442060.014
mapk cascadeGO:00001652810.014
positive regulation of response to woundingGO:1903036660.014
regulation of cell cycle phase transitionGO:1901987770.014
membrane organizationGO:00610242450.014
positive regulation of mitotic cell cycleGO:0045931410.014
meiotic nuclear divisionGO:00071261150.013
dna replicationGO:0006260520.013
regulation of gtp catabolic processGO:00331241130.013
regulation of neuron deathGO:19012141340.013
regulation of vasculature developmentGO:1901342880.013
leukocyte differentiationGO:00025213420.013
male gamete generationGO:00482322850.013
transmission of nerve impulseGO:0019226760.013
limb developmentGO:00601731660.013
regulation of cellular amine metabolic processGO:0033238200.013
ion transmembrane transportGO:00342203610.013
action potentialGO:0001508780.013
regulation of ossificationGO:00302781120.013
apoptotic signaling pathwayGO:00971903060.013
protein methylationGO:0006479810.013
negative regulation of dna replicationGO:000815640.013
cellular amine metabolic processGO:0044106440.013
cytokine productionGO:00018163190.013
protein alkylationGO:0008213810.013
blood vessel morphogenesisGO:00485142850.013
positive regulation of organelle organizationGO:00106381280.013
negative regulation of rho gtpase activityGO:003425910.013
positive regulation of hydrolase activityGO:00513451480.013
retina morphogenesis in camera type eyeGO:0060042450.013
sensory perceptionGO:00076002450.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
glycosyl compound catabolic processGO:19016582060.012
adult behaviorGO:00305341350.012
regulation of embryonic developmentGO:0045995710.012
regulation of purine nucleotide metabolic processGO:19005421690.012
regulation of mitotic cell cycleGO:00073461260.012
regulation of cytoskeleton organizationGO:00514931220.012
embryonic epithelial tube formationGO:00018381300.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
regulation of neurotransmitter levelsGO:0001505870.012
regulation of cellular response to stressGO:00801351590.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
mitotic sister chromatid segregationGO:0000070140.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
mitotic cell cycle checkpointGO:0007093310.012
positive regulation of nucleotide metabolic processGO:00459811140.012
negative regulation of protein processingGO:0010955790.012
cellular homeostasisGO:00197252400.012
positive regulation of nervous system developmentGO:00519622210.012
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.011
cell adhesionGO:00071553290.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
negative regulation of cell cycle processGO:0010948690.011
hepaticobiliary system developmentGO:0061008670.011
negative regulation of neuron deathGO:1901215980.011
inorganic cation transmembrane transportGO:00986622070.011
positive regulation of translational initiationGO:004594840.011
regulation of purine nucleotide catabolic processGO:00331211220.011
actin mediated cell contractionGO:0070252150.011
negative regulation of mitotic cell cycleGO:0045930580.011
regulation of system processGO:00440572000.011
neuron deathGO:00709971540.011
regulation of planar cell polarity pathway involved in axis elongationGO:200004030.010
calcium ion homeostasisGO:00550741270.010
histone h3 k9 methylationGO:0051567170.010
regulation of protein maturationGO:1903317960.010
developmental growth involved in morphogenesisGO:00605601380.010
regulation of cell shapeGO:0008360390.010
cell substrate adhesionGO:00315891300.010
modification dependent protein catabolic processGO:00199411330.010
negative regulation of cell cycle phase transitionGO:1901988480.010
negative regulation of protein maturationGO:1903318790.010

Smek2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.037
disease of cellular proliferationDOID:1456600.037
nervous system diseaseDOID:86300.011
disease of anatomical entityDOID:700.011
sensory system diseaseDOID:005015500.010