Mus musculus

0 known processes

Rapgef6

Rap guanine nucleotide exchange factor (GEF) 6

(Aliases: mKIAA4052,C030018K18Rik,KIAA4052,AI844632,Pdzgef2,PDZ-GEF2,BB085664,Ragef2,RA-GEF-2,A530068K01)

Rapgef6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone modificationGO:00165701590.176
ras protein signal transductionGO:0007265770.151
regulation of cellular amine metabolic processGO:0033238200.144
regulation of cellular amino acid metabolic processGO:000652150.126
covalent chromatin modificationGO:00165691630.122
positive regulation of cellular amine metabolic processGO:003324050.116
amine metabolic processGO:0009308450.115
cellular ketone metabolic processGO:0042180840.110
positive regulation of cellular amino acid metabolic processGO:004576430.109
cellular amino acid metabolic processGO:00065201030.107
cellular amine metabolic processGO:0044106440.097
regulation of cellular ketone metabolic processGO:0010565660.095
organic cyclic compound catabolic processGO:19013612950.094
Human Mouse Worm Fly
peptidyl amino acid modificationGO:00181933360.093
purine nucleoside catabolic processGO:00061522050.093
Human Mouse Worm Fly
purine ribonucleoside triphosphate catabolic processGO:00092071990.091
Human Mouse Worm Fly
purine nucleoside triphosphate metabolic processGO:00091442260.091
Human Mouse Worm Fly
nucleoside catabolic processGO:00091642060.091
Human Mouse Worm Fly
cellular nitrogen compound catabolic processGO:00442702800.087
Human Mouse Worm Fly
histone methylationGO:0016571710.087
organonitrogen compound catabolic processGO:19015652640.086
Human Mouse Worm Fly
heterocycle catabolic processGO:00467002800.079
Human Mouse Worm Fly
small gtpase mediated signal transductionGO:0007264970.076
purine containing compound metabolic processGO:00725213110.076
Human Mouse Worm Fly
protein modification by small protein conjugation or removalGO:00706472070.073
glycosyl compound catabolic processGO:19016582060.072
Human Mouse Worm Fly
regulation of kinase activityGO:00435492490.071
Mouse
guanosine containing compound metabolic processGO:19010681440.071
Human Mouse Worm Fly
purine nucleotide catabolic processGO:00061952110.069
Human Mouse Worm Fly
aromatic compound catabolic processGO:00194392860.068
Human Mouse Worm Fly
positive regulation of protein phosphorylationGO:00019342420.067
Mouse
positive regulation of protein modification processGO:00314012990.066
Mouse
purine ribonucleotide metabolic processGO:00091502900.065
Human Mouse Worm Fly
chromatin organizationGO:00063252060.065
rho protein signal transductionGO:0007266320.064
ribonucleoside triphosphate catabolic processGO:00092031990.061
Human Mouse Worm Fly
nucleotide metabolic processGO:00091173320.061
Human Mouse Worm Fly
glycerolipid metabolic processGO:00464861220.058
ribonucleoside catabolic processGO:00424542060.058
Human Mouse Worm Fly
purine ribonucleotide catabolic processGO:00091542080.058
Human Mouse Worm Fly
nucleoside metabolic processGO:00091162460.057
Human Mouse Worm Fly
nucleoside triphosphate catabolic processGO:00091432050.057
Human Mouse Worm Fly
purine nucleotide metabolic processGO:00061633020.056
Human Mouse Worm Fly
regulation of gtp catabolic processGO:00331241130.056
Human Mouse Worm Fly
cytokine productionGO:00018163190.052
methylationGO:00322591340.051
organophosphate catabolic processGO:00464342320.051
Human Mouse Worm Fly
nucleoside phosphate metabolic processGO:00067533380.050
Human Mouse Worm Fly
histone h3 k4 trimethylationGO:008018250.049
ribonucleoside metabolic processGO:00091192450.047
Human Mouse Worm Fly
cell type specific apoptotic processGO:00972852680.047
Mouse
purine containing compound catabolic processGO:00725232130.047
Human Mouse Worm Fly
purine nucleoside triphosphate catabolic processGO:00091462030.045
Human Mouse Worm Fly
nucleotide catabolic processGO:00091662170.045
Human Mouse Worm Fly
mapk cascadeGO:00001652810.044
Mouse Fly
regulation of organelle organizationGO:00330432890.043
histone lysine methylationGO:0034968500.042
regulation of ras gtpase activityGO:0032318880.042
Mouse Worm Fly
nucleobase containing small molecule metabolic processGO:00550863520.042
Human Mouse Worm Fly
guanosine containing compound catabolic processGO:19010691440.042
Human Mouse Worm Fly
macromolecule catabolic processGO:00090572810.041
positive regulation of cell deathGO:00109422240.041
Mouse
establishment of vesicle localizationGO:0051650810.041
glycerophospholipid metabolic processGO:0006650710.041
macromolecule methylationGO:00434141200.041
carbohydrate metabolic processGO:00059752300.040
nucleoside phosphate catabolic processGO:19012922220.040
Human Mouse Worm Fly
homeostasis of number of cellsGO:00488722100.040
positive regulation of apoptotic processGO:00430652170.040
Mouse
protein autophosphorylationGO:0046777610.040
development of primary sexual characteristicsGO:00451371430.039
histone h3 k9 trimethylationGO:003612460.038
ribose phosphate metabolic processGO:00196932910.038
Human Mouse Worm Fly
regulation of transferase activityGO:00513382630.038
Mouse
cellular response to dna damage stimulusGO:00069742070.038
regulation of neuron differentiationGO:00456642810.037
Mouse Fly
cellular lipid metabolic processGO:00442553230.037
purine ribonucleoside metabolic processGO:00461282410.037
Human Mouse Worm Fly
regulation of hydrolase activityGO:00513362460.035
Human Mouse Worm Fly
chromatin modificationGO:00165681870.035
ribonucleotide catabolic processGO:00092612080.035
Human Mouse Worm Fly
chemotaxisGO:00069352470.034
regulation of mapk cascadeGO:00434082480.034
Mouse
cellular response to lipidGO:00713961450.034
regulation of lymphocyte activationGO:00512492400.033
cytoplasmic transportGO:00164822340.033
regulation of purine nucleotide metabolic processGO:19005421690.033
Human Mouse Worm Fly
organelle fissionGO:00482851700.032
protein methylationGO:0006479810.032
transmembrane transportGO:00550854120.032
leukocyte differentiationGO:00025213420.032
nuclear transportGO:00511691390.032
regulation of cell motilityGO:20001452360.031
Mouse
peptidyl serine phosphorylationGO:0018105740.031
hematopoietic progenitor cell differentiationGO:00022441430.031
histone h3 k9 methylationGO:0051567170.030
nucleoside triphosphate metabolic processGO:00091412300.030
Human Mouse Worm Fly
response to molecule of bacterial originGO:00022371430.030
protein alkylationGO:0008213810.030
glycosyl compound metabolic processGO:19016572460.030
Human Mouse Worm Fly
purine ribonucleoside catabolic processGO:00461302050.029
Human Mouse Worm Fly
purine ribonucleoside triphosphate metabolic processGO:00092052200.028
Human Mouse Worm Fly
regulation of rho protein signal transductionGO:0035023710.028
gtp catabolic processGO:00061841430.028
Human Mouse Worm Fly
regulation of cellular catabolic processGO:00313292420.028
Human Mouse Worm Fly
regulation of cell activationGO:00508652890.028
carbohydrate derivative catabolic processGO:19011362310.028
Human Mouse Worm Fly
b cell activationGO:00421131610.028
organelle localizationGO:00516401790.027
gland developmentGO:00487323300.027
regulation of protein kinase activityGO:00458592320.027
Mouse
regulation of membrane potentialGO:00423911920.027
negative regulation of molecular functionGO:00440922580.027
ribonucleoside triphosphate metabolic processGO:00091992200.026
Human Mouse Worm Fly
positive regulation of lymphocyte activationGO:00512511400.026
ion transmembrane transportGO:00342203610.026
mitotic cell cycle processGO:19030471590.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.026
protein catabolic processGO:00301632210.026
protein localization to organelleGO:00333651850.026
calcium ion transportGO:00068161590.026
axonogenesisGO:00074092740.025
Fly
synaptic transmissionGO:00072683290.025
regulation of nucleotide metabolic processGO:00061401690.025
Human Mouse Worm Fly
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.025
cell adhesionGO:00071553290.025
negative regulation of protein metabolic processGO:00512482820.024
regulation of apoptotic signaling pathwayGO:20012331970.024
histone h4 k20 methylationGO:003477080.024
regulation of nucleotide catabolic processGO:00308111220.024
Human Mouse Worm Fly
apoptotic signaling pathwayGO:00971903060.024
regulation of nucleoside metabolic processGO:00091181300.024
Human Mouse Worm Fly
positive regulation of hydrolase activityGO:00513451480.024
Human Mouse Worm Fly
action potentialGO:0001508780.024
learning or memoryGO:00076111480.024
sensory perceptionGO:00076002450.024
ribonucleotide metabolic processGO:00092592910.024
Human Mouse Worm Fly
nuclear divisionGO:00002801580.024
sensory organ morphogenesisGO:00905962420.024
Fly
lymphocyte differentiationGO:00300982420.023
regulation of purine nucleotide catabolic processGO:00331211220.023
Human Mouse Worm Fly
regulation of protein complex assemblyGO:0043254830.023
peptidyl serine modificationGO:0018209830.023
regulation of neuron projection developmentGO:00109751690.023
Mouse
regulation of cytokine productionGO:00018172660.023
extrinsic apoptotic signaling pathwayGO:00971911260.023
gtp metabolic processGO:00460391440.022
Human Mouse Worm Fly
dna metabolic processGO:00062593030.022
immune effector processGO:00022523210.022
adaptive immune responseGO:00022501550.022
protein localization to nucleusGO:00345041210.022
cellular response to lipopolysaccharideGO:0071222770.022
protein ubiquitinationGO:00165671710.022
response to organic cyclic compoundGO:00140701980.022
Mouse
leukocyte mediated immunityGO:00024431740.022
regulation of ras protein signal transductionGO:00465781140.022
Mouse Worm Fly
muscle system processGO:00030121410.022
dna repairGO:00062811070.022
mitotic cell cycleGO:00002781950.021
dephosphorylationGO:00163111290.021
cellular response to molecule of bacterial originGO:0071219830.021
phospholipid metabolic processGO:0006644870.021
microtubule cytoskeleton organizationGO:00002261570.021
heart morphogenesisGO:00030071780.021
cellular response to hormone stimulusGO:00328701500.021
multicellular organism growthGO:00352641610.021
inorganic ion transmembrane transportGO:00986602340.021
regulation of cellular component biogenesisGO:00440871810.021
cellular response to organonitrogen compoundGO:00714171450.021
Mouse
cellular macromolecule catabolic processGO:00442652060.020
cation transmembrane transportGO:00986552660.020
positive regulation of nervous system developmentGO:00519622210.020
Mouse
histone deubiquitinationGO:001657820.020
negative regulation of cellular amine metabolic processGO:003323910.020
neuron deathGO:00709971540.020
gene silencing by rnaGO:0031047190.020
intracellular protein transportGO:00068862040.020
positive regulation of gtpase activityGO:0043547850.020
Human Mouse Worm Fly
cellular homeostasisGO:00197252400.020
purine nucleoside metabolic processGO:00422782410.020
Human Mouse Worm Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.019
vesicle localizationGO:0051648860.019
response to lipopolysaccharideGO:00324961280.019
protein kinase b signalingGO:0043491740.019
negative regulation of nervous system developmentGO:00519611560.019
Mouse
positive regulation of organelle organizationGO:00106381280.019
embryonic organ morphogenesisGO:00485622760.019
actin filament organizationGO:00070151130.019
nucleocytoplasmic transportGO:00069131390.019
myeloid cell differentiationGO:00300992330.019
b cell differentiationGO:0030183780.019
regulation of cell migrationGO:00303342190.019
Mouse
negative regulation of cellular component organizationGO:00511291940.019
Mouse
negative regulation of cell developmentGO:00107211690.019
Mouse
positive regulation of programmed cell deathGO:00430682180.018
Mouse
cellular response to cytokine stimulusGO:00713451890.018
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.018
divalent metal ion transportGO:00708381720.018
response to growth factorGO:00708481980.018
negative regulation of phosphorus metabolic processGO:00105631840.018
positive regulation of cell activationGO:00508671580.018
regulation of vesicle mediated transportGO:00606271390.018
Mouse
membrane organizationGO:00610242450.018
neuronal action potentialGO:0019228540.018
posttranscriptional regulation of gene expressionGO:00106081550.018
cellular protein complex assemblyGO:00436231160.018
regulation of cell cycleGO:00517262810.018
regulation of cell adhesionGO:00301551540.018
cation transportGO:00068123990.018
negative regulation of cell proliferationGO:00082852960.017
Mouse
cognitionGO:00508901490.017
regulation of secretionGO:00510462740.017
Mouse
negative regulation of phosphorylationGO:00423261660.017
regulation of neuron apoptotic processGO:00435231220.017
regulation of neuron deathGO:19012141340.017
inorganic cation transmembrane transportGO:00986622070.017
regulation of cell cycle processGO:00105641600.017
skeletal system developmentGO:00015013560.016
protein maturationGO:00516041760.016
regulation of rho gtpase activityGO:0032319580.016
blood vessel morphogenesisGO:00485142850.016
Mouse
peptidyl lysine methylationGO:0018022290.016
multicellular organismal signalingGO:0035637910.016
ubiquitin dependent protein catabolic processGO:00065111290.016
neural tube developmentGO:00219151600.016
hindbrain developmentGO:00309021280.016
genetic imprintingGO:0071514270.016
regulation of protein kinase b signalingGO:0051896560.016
lipid localizationGO:00108761260.016
positive regulation of cell cycle processGO:0090068610.016
protein polymerizationGO:0051258570.016
t cell activationGO:00421102890.016
divalent inorganic cation transportGO:00725111780.016
cell activation involved in immune responseGO:00022631260.016
negative regulation of organelle organizationGO:0010639900.016
regulation of system processGO:00440572000.016
anion transportGO:00068201770.015
embryonic placenta developmentGO:0001892980.015
gonad developmentGO:00084061410.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
Human Mouse Worm Fly
cellular carbohydrate metabolic processGO:00442621190.015
leukocyte homeostasisGO:0001776790.015
epithelial tube morphogenesisGO:00605623030.015
leukocyte migrationGO:00509001240.015
dendrite developmentGO:00163581150.015
Mouse
organic hydroxy compound metabolic processGO:19016152030.015
Mouse
bone developmentGO:00603481200.015
leukocyte activation involved in immune responseGO:00023661260.015
rna processingGO:00063961050.015
regulation of nuclear divisionGO:0051783560.015
nuclear importGO:0051170950.015
epithelial tube formationGO:00721751300.015
regulation of histone methylationGO:0031060300.015
actin cytoskeleton organizationGO:00300362200.015
glycoprotein metabolic processGO:00091001160.015
epithelial cell developmentGO:00020641590.014
endocytosisGO:00068971680.014
protein modification by small protein conjugationGO:00324461870.014
meiotic cell cycleGO:00513211220.014
ameboidal type cell migrationGO:00016671280.014
regulation of cytoplasmic transportGO:19036491120.014
response to organonitrogen compoundGO:00102432460.014
Mouse
regulation of ion transportGO:00432692150.014
regulation of chromosome organizationGO:0033044830.014
cellular chemical homeostasisGO:00550822150.014
apical constrictionGO:000338340.014
regulation of cytoskeleton organizationGO:00514931220.014
carbohydrate derivative biosynthetic processGO:19011371830.014
inflammatory responseGO:00069542440.014
regulation of lymphocyte differentiationGO:00456191070.014
dna recombinationGO:0006310920.014
camera type eye developmentGO:00430102660.014
spermatogenesisGO:00072832840.014
digestive tract developmentGO:00485651900.014
regulation of cell divisionGO:0051302760.014
regulation of adaptive immune responseGO:0002819900.014
negative regulation of neuron deathGO:1901215980.014
microtubule based processGO:00070172360.014
response to peptide hormoneGO:00434341270.014
g protein coupled receptor signaling pathwayGO:00071862430.014
Mouse
regulation of chromatin modificationGO:1903308570.014
development of primary male sexual characteristicsGO:0046546880.014
cytokine mediated signaling pathwayGO:00192211150.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
morphogenesis of embryonic epitheliumGO:00163311590.013
Fly
developmental growth involved in morphogenesisGO:00605601380.013
positive regulation of cell developmentGO:00107202370.013
Mouse
calcium ion homeostasisGO:00550741270.013
transmission of nerve impulseGO:0019226760.013
digestive tract morphogenesisGO:00485461470.013
respiratory system developmentGO:00605411900.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
cellular response to biotic stimulusGO:0071216920.013
protein import into nucleusGO:0006606950.013
fertilizationGO:00095661270.013
muscle cell differentiationGO:00426922610.013
negative regulation of neuron apoptotic processGO:0043524920.013
modification dependent macromolecule catabolic processGO:00436321330.013
angiogenesisGO:00015252010.013
blood circulationGO:00080151950.013
response to light stimulusGO:00094161350.013
mrna metabolic processGO:0016071840.013
positive regulation of transferase activityGO:00513471670.013
Mouse
regulation of transcription by chromatin organizationGO:003440100.013
lateral inhibitionGO:004633110.013
anatomical structure homeostasisGO:00602491450.013
forebrain developmentGO:00309003020.013
Mouse
establishment of organelle localizationGO:00516561220.013
muscle tissue developmentGO:00605373080.013
lymphocyte activation involved in immune responseGO:0002285930.013
negative regulation of immune system processGO:00026832090.013
meiotic nuclear divisionGO:00071261150.013
cell divisionGO:00513011200.013
endodermal cell fate specificationGO:000171440.013
divalent inorganic cation homeostasisGO:00725071380.013
positive regulation of mapk cascadeGO:00434101700.013
Mouse
synaptic vesicle transportGO:0048489570.013
regulation of map kinase activityGO:00434051200.012
regulation of cell morphogenesis involved in differentiationGO:00107691510.012
Mouse
male gamete generationGO:00482322850.012
nitrogen compound transportGO:00717052710.012
Mouse
central nervous system neuron differentiationGO:00219531620.012
Mouse
chromosome segregationGO:0007059480.012
protein importGO:00170381010.012
neural precursor cell proliferationGO:00613511210.012
regulation of cell substrate adhesionGO:0010810730.012
heterochromatin organizationGO:007082840.012
positive regulation of nucleoside metabolic processGO:0045979910.012
Human Mouse Worm Fly
alpha beta t cell activationGO:0046631910.012
muscle contractionGO:00069361010.012
embryonic epithelial tube formationGO:00018381300.012
sensory perception of mechanical stimulusGO:00509541070.012
positive regulation of apoptotic signaling pathwayGO:2001235950.012
stem cell proliferationGO:00720891170.012
positive regulation of protein kinase activityGO:00458601440.012
Mouse
positive regulation of nucleotide catabolic processGO:0030813880.012
Human Mouse Worm Fly
lipid transportGO:0006869980.012
establishment of protein localization to organelleGO:00725941180.012
regulation of leukocyte mediated immunityGO:00027031040.012
regulation of wnt signaling pathwayGO:00301111230.012
neural tube formationGO:00018411080.012
cellular response to peptide hormone stimulusGO:0071375920.012
regulation of protein localizationGO:00328802310.012
axon guidanceGO:00074111410.012
placenta developmentGO:00018901400.012
tube formationGO:00351481400.012
neuron apoptotic processGO:00514021420.012
rna interferenceGO:001624620.012
regulation of establishment of protein localizationGO:00702011810.012
t cell differentiationGO:00302171740.012
dna dependent dna replication maintenance of fidelityGO:004500530.012
negative regulation of cellular amino acid metabolic processGO:004576300.012
peptidyl threonine phosphorylationGO:0018107310.012
positive regulation of cytokine productionGO:00018191740.012
retina homeostasisGO:0001895230.011
sensory system developmentGO:004888030.011
lipid modificationGO:0030258650.011
male sex differentiationGO:00466611090.011
positive regulation of kinase activityGO:00336741550.011
Mouse
stem cell developmentGO:00488642190.011
Fly
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.011
cell substrate adhesionGO:00315891300.011
histone h3 k4 methylationGO:0051568230.011
lymphocyte mediated immunityGO:00024491390.011
epithelial to mesenchymal transitionGO:0001837470.011
actin filament polymerizationGO:0030041440.011
production of molecular mediator of immune responseGO:00024401030.011
synapse organizationGO:00508081250.011
regulation of homeostatic processGO:00328441820.011
negative regulation of protein modification processGO:00314001630.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
response to acid chemicalGO:00011011110.011
axon ensheathmentGO:0008366760.011
neuron projection guidanceGO:00974851410.011
glucose homeostasisGO:00425931280.011
regulation of chromatin organizationGO:1902275570.011
phosphatidylinositol metabolic processGO:0046488450.011
positive regulation of nucleotide metabolic processGO:00459811140.011
Human Mouse Worm Fly
establishment of synaptic vesicle localizationGO:0097480570.011
epithelial cell proliferationGO:00506731740.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
organic anion transportGO:00157111370.011
regulation of b cell activationGO:0050864810.011
telencephalon developmentGO:00215371860.011
jak stat cascadeGO:0007259420.011
positive regulation of gtp catabolic processGO:0033126850.011
Human Mouse Worm Fly
regulation of response to woundingGO:19030341890.011
cellular calcium ion homeostasisGO:00068741190.010
tissue homeostasisGO:00018941150.010
second messenger mediated signalingGO:0019932730.010
Mouse
hexose metabolic processGO:0019318980.010
peptidyl tyrosine modificationGO:00182121450.010
sensory perception of soundGO:0007605970.010
branching morphogenesis of an epithelial tubeGO:00487541590.010
calcium ion transmembrane transportGO:0070588850.010
mitotic sister chromatid cohesionGO:000706410.010
positive regulation of tor signalingGO:003200830.010
gastrulationGO:00073691160.010
regulation of histone modificationGO:0031056560.010
regulation of transmembrane transportGO:00347621280.010
stress activated protein kinase signaling cascadeGO:0031098810.010
double strand break repairGO:0006302480.010
regulation of peptidyl serine phosphorylationGO:0033135390.010
single organism nuclear importGO:1902593950.010
regulation of t cell activationGO:00508631700.010
lymphocyte homeostasisGO:0002260640.010
positive regulation of immune effector processGO:00026991070.010
nucleoside monophosphate metabolic processGO:0009123850.010
lymphocyte apoptotic processGO:0070227540.010
cellular response to extracellular stimulusGO:0031668810.010
regulation of defense responseGO:00313472330.010

Rapgef6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.024
organ system cancerDOID:005068600.024
cancerDOID:16200.024
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
central nervous system diseaseDOID:33100.012
immune system diseaseDOID:291400.011
connective tissue diseaseDOID:6500.011
musculoskeletal system diseaseDOID:1700.011
bone diseaseDOID:008000100.011