Mus musculus

55 known processes

Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

(Aliases: Pedfl,EPC-1,Pedf,AI195227,Sdf3)

Serpinf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
extracellular structure organizationGO:00430621480.229
Mouse
oxidation reduction processGO:00551143420.113
glycoprotein metabolic processGO:00091001160.091
regulation of cellular ketone metabolic processGO:0010565660.084
immune effector processGO:00022523210.081
protein processingGO:00164851630.073
Mouse
regulation of proteolysisGO:00301621640.071
Mouse
innate immune responseGO:00450871570.070
defense response to other organismGO:00985421970.067
ossificationGO:00015032160.066
cellular amino acid metabolic processGO:00065201030.062
peptide metabolic processGO:0006518460.062
carbohydrate metabolic processGO:00059752300.061
regulation of hydrolase activityGO:00513362460.058
Mouse
skeletal system developmentGO:00015013560.058
sulfur compound metabolic processGO:00067901000.058
negative regulation of protein activation cascadeGO:200025830.055
regulation of cellular response to stressGO:00801351590.055
response to organic cyclic compoundGO:00140701980.054
activation of immune responseGO:00022531380.053
small gtpase mediated signal transductionGO:0007264970.051
complement activationGO:0006956160.051
regulation of peptidase activityGO:0052547960.049
Mouse
monocarboxylic acid metabolic processGO:00327871910.049
humoral immune responseGO:0006959570.048
regulation of apoptotic signaling pathwayGO:20012331970.047
regulation of protein processingGO:0070613960.047
Mouse
fat cell differentiationGO:00454441600.047
cell type specific apoptotic processGO:00972852680.046
protein maturationGO:00516041760.046
Mouse
negative regulation of protein metabolic processGO:00512482820.045
Mouse
ras protein signal transductionGO:0007265770.045
negative regulation of immune system processGO:00026832090.044
organonitrogen compound biosynthetic processGO:19015661920.044
extracellular matrix organizationGO:00301981470.043
Mouse
protein hydroxylationGO:001812640.041
response to organonitrogen compoundGO:00102432460.041
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.040
connective tissue developmentGO:00614481790.040
extrinsic apoptotic signaling pathwayGO:00971911260.039
bone developmentGO:00603481200.039
negative regulation of cell proliferationGO:00082852960.038
organelle assemblyGO:00709251770.038
regulation of defense responseGO:00313472330.037
cellular nitrogen compound catabolic processGO:00442702800.037
regulation of cellular amino acid metabolic processGO:000652150.037
cell substrate adhesionGO:00315891300.036
regulation of cytokine productionGO:00018172660.036
Mouse
cellular modified amino acid metabolic processGO:0006575630.036
cellular response to organonitrogen compoundGO:00714171450.036
positive regulation of protein modification processGO:00314012990.035
regulation of innate immune responseGO:0045088910.035
regulation of cell projection organizationGO:00313442060.035
spermatogenesisGO:00072832840.034
negative regulation of apoptotic signaling pathwayGO:20012341040.034
response to molecule of bacterial originGO:00022371430.034
mapk cascadeGO:00001652810.034
cytokine productionGO:00018163190.034
Mouse
negative regulation of protein processingGO:0010955790.033
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.032
Mouse
cell adhesionGO:00071553290.032
rho protein signal transductionGO:0007266320.031
digestive system developmentGO:00551232000.031
biomineral tissue developmentGO:0031214640.031
positive regulation of cellular amine metabolic processGO:003324050.031
muscle system processGO:00030121410.031
organic hydroxy compound metabolic processGO:19016152030.031
regulation of mapk cascadeGO:00434082480.031
inflammatory responseGO:00069542440.030
protein activation cascadeGO:0072376190.030
regulation of cellular amine metabolic processGO:0033238200.030
regulation of ras protein signal transductionGO:00465781140.029
sensory organ morphogenesisGO:00905962420.029
monosaccharide metabolic processGO:00059961060.029
respiratory tube developmentGO:00303231670.029
blood circulationGO:00080151950.029
Mouse
regulation of hormone levelsGO:00108172110.028
cellular ketone metabolic processGO:0042180840.028
anatomical structure homeostasisGO:00602491450.028
proteoglycan metabolic processGO:0006029380.028
reactive oxygen species biosynthetic processGO:190340980.028
dna metabolic processGO:00062593030.027
complement activation lectin pathwayGO:000186750.027
regulation of organ morphogenesisGO:20000271440.027
defense response to bacteriumGO:00427421190.027
camera type eye developmentGO:00430102660.027
apoptotic signaling pathwayGO:00971903060.026
cellular lipid metabolic processGO:00442553230.026
transmembrane transportGO:00550854120.026
blood vessel morphogenesisGO:00485142850.026
nucleoside phosphate metabolic processGO:00067533380.026
positive regulation of protein phosphorylationGO:00019342420.025
intracellular protein transportGO:00068862040.025
skeletal system morphogenesisGO:00487052030.025
lymphocyte mediated immunityGO:00024491390.025
chondroitin sulfate proteoglycan metabolic processGO:0050654200.025
cytoplasmic transportGO:00164822340.025
negative regulation of phosphorus metabolic processGO:00105631840.024
regulation of cell adhesionGO:00301551540.024
cardiac chamber morphogenesisGO:0003206930.024
male gamete generationGO:00482322850.024
negative regulation of protein maturationGO:1903318790.024
Mouse
negative regulation of phospholipase activityGO:001051940.024
nucleobase containing small molecule metabolic processGO:00550863520.024
respiratory system developmentGO:00605411900.024
cartilage developmentGO:00512161400.023
negative regulation of hydrolase activityGO:0051346710.023
Mouse
cellular response to dna damage stimulusGO:00069742070.023
ear developmentGO:00435832000.023
regulation of protein serine threonine kinase activityGO:00719001570.023
collagen fibril organizationGO:0030199320.023
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.023
regulation of protein transportGO:00512231630.023
developmental growth involved in morphogenesisGO:00605601380.023
chemotaxisGO:00069352470.023
negative regulation of intracellular signal transductionGO:19025321670.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.022
regulation of anatomical structure sizeGO:00900661780.022
Mouse
macromolecule catabolic processGO:00090572810.022
response to decreased oxygen levelsGO:0036293590.022
regulation of kinase activityGO:00435492490.022
response to endoplasmic reticulum stressGO:0034976530.022
regulation of neuron differentiationGO:00456642810.022
epithelial cell developmentGO:00020641590.022
cellular amine metabolic processGO:0044106440.022
regulation of fat cell differentiationGO:0045598810.022
response to lipopolysaccharideGO:00324961280.022
peptidyl amino acid modificationGO:00181933360.022
hexose metabolic processGO:0019318980.021
response to oxygen levelsGO:0070482620.021
brown fat cell differentiationGO:0050873360.021
regulation of endopeptidase activityGO:0052548890.021
Mouse
cellular response to lipidGO:00713961450.021
regulation of inflammatory responseGO:00507271470.021
carbohydrate derivative biosynthetic processGO:19011371830.021
amine metabolic processGO:0009308450.021
hormone metabolic processGO:0042445860.021
organonitrogen compound catabolic processGO:19015652640.020
reactive oxygen species metabolic processGO:0072593840.020
sensory perceptionGO:00076002450.020
positive regulation of nervous system developmentGO:00519622210.020
Human
response to acid chemicalGO:00011011110.020
regulation of neuron projection developmentGO:00109751690.020
regulation of cell migrationGO:00303342190.020
embryonic organ morphogenesisGO:00485622760.020
tissue homeostasisGO:00018941150.020
chondroitin sulfate metabolic processGO:0030204170.020
negative regulation of molecular functionGO:00440922580.020
Mouse
nitrogen compound transportGO:00717052710.020
single organism nuclear importGO:1902593950.019
aromatic compound catabolic processGO:00194392860.019
regulation of cellular component biogenesisGO:00440871810.019
positive regulation of reactive oxygen species biosynthetic processGO:190342820.019
skin developmentGO:00435882200.019
regulation of cell morphogenesis involved in differentiationGO:00107691510.019
negative regulation of proteolysisGO:0045861740.019
Mouse
cellular amide metabolic processGO:0043603580.019
regulation of cell substrate adhesionGO:0010810730.019
urogenital system developmentGO:00016552610.019
signal transduction in absence of ligandGO:0038034550.019
gland developmentGO:00487323300.019
regulation of reactive oxygen species biosynthetic processGO:190342620.019
negative regulation of blood vessel morphogenesisGO:2000181250.019
digestive tract developmentGO:00485651900.019
epidermis developmentGO:00085441870.019
multicellular organismal homeostasisGO:00488711640.018
cellular response to cytokine stimulusGO:00713451890.018
glucose metabolic processGO:0006006920.018
cellular component assembly involved in morphogenesisGO:00109271390.018
peptidyl serine modificationGO:0018209830.018
odontogenesisGO:0042476780.018
symbiosis encompassing mutualism through parasitismGO:0044403830.018
regulation of reactive oxygen species metabolic processGO:2000377400.018
organic cyclic compound catabolic processGO:19013612950.018
transmission of nerve impulseGO:0019226760.018
positive regulation of defense responseGO:00313491240.018
cell killingGO:0001906670.018
cell growthGO:00160491300.018
regulation of ossificationGO:00302781120.018
muscle cell differentiationGO:00426922610.018
muscle tissue developmentGO:00605373080.018
engulfment of apoptotic cellGO:004365230.018
ribose phosphate metabolic processGO:00196932910.018
regulation of transmembrane transportGO:00347621280.018
negative regulation of phosphorylationGO:00423261660.017
glycerolipid metabolic processGO:00464861220.017
carbohydrate biosynthetic processGO:0016051740.017
hexose biosynthetic processGO:0019319390.017
purine containing compound metabolic processGO:00725213110.017
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.017
small molecule catabolic processGO:0044282710.017
protein targetingGO:00066051430.017
fibril organizationGO:009743520.017
regulation of protein kinase activityGO:00458592320.017
cell recognitionGO:0008037830.016
glycosaminoglycan metabolic processGO:0030203340.016
heart morphogenesisGO:00030071780.016
t cell activationGO:00421102890.016
cellular response to transforming growth factor beta stimulusGO:0071560880.016
posttranscriptional regulation of gene expressionGO:00106081550.016
nuclear importGO:0051170950.016
regulation of tooth mineralizationGO:007017020.016
regulation of nucleocytoplasmic transportGO:0046822730.016
response to oxidative stressGO:00069791230.016
protein localization to organelleGO:00333651850.016
regulation of map kinase activityGO:00434051200.016
anion transportGO:00068201770.016
zygotic determination of anterior posterior axis embryoGO:000735430.016
regulation of response to woundingGO:19030341890.016
cellular response to biotic stimulusGO:0071216920.016
negative regulation of angiogenesisGO:0016525250.016
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.016
reactive nitrogen species metabolic processGO:200105700.016
lipid modificationGO:0030258650.016
actin cytoskeleton organizationGO:00300362200.016
embryonic skeletal system developmentGO:00487061200.016
interspecies interaction between organismsGO:0044419830.015
establishment of protein localization to organelleGO:00725941180.015
skeletal muscle satellite cell maintenance involved in skeletal muscle regenerationGO:001483430.015
regulation of establishment of protein localizationGO:00702011810.015
ribonucleotide metabolic processGO:00092592910.015
mucopolysaccharide metabolic processGO:1903510250.015
circulatory system processGO:00030131970.015
Mouse
production of molecular mediator of immune responseGO:00024401030.015
lymphocyte differentiationGO:00300982420.015
negative regulation of multi organism processGO:0043901680.015
positive regulation of transferase activityGO:00513471670.015
positive regulation of apoptotic signaling pathwayGO:2001235950.015
stem cell developmentGO:00488642190.015
regulation of epithelial cell proliferationGO:00506781410.015
response to peptideGO:19016521360.015
canonical wnt signaling pathwayGO:00600701300.015
regulation of angiogenesisGO:0045765810.015
cellular response to external stimulusGO:0071496880.015
mesenchymal cell differentiationGO:00487621070.015
positive regulation of cell developmentGO:00107202370.014
Human
striated muscle tissue developmentGO:00147062930.014
limb morphogenesisGO:00351081490.014
positive regulation of kinase activityGO:00336741550.014
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.014
angiogenesisGO:00015252010.014
lung developmentGO:00303241640.014
glucose homeostasisGO:00425931280.014
oocyte axis specificationGO:000730920.014
gliogenesisGO:00420631410.014
acylglycerol metabolic processGO:0006639550.014
purine nucleotide metabolic processGO:00061633020.014
regulation of cell sizeGO:0008361720.014
wnt signaling pathwayGO:00160551880.014
negative regulation of endopeptidase activityGO:0010951440.014
Mouse
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.014
negative regulation of dna replicationGO:000815640.014
negative regulation of cellular component organizationGO:00511291940.014
regulation of intracellular transportGO:00323861590.014
response to transforming growth factor betaGO:0071559880.014
morphogenesis of embryonic epitheliumGO:00163311590.014
rhythmic processGO:00485111740.013
regulation of rho protein signal transductionGO:0035023710.013
small molecule biosynthetic processGO:00442831320.013
cell chemotaxisGO:0060326810.013
heterocycle catabolic processGO:00467002800.013
ion transmembrane transportGO:00342203610.013
regulation of organelle organizationGO:00330432890.013
cation transmembrane transportGO:00986552660.013
mesenchyme developmentGO:00604851520.013
positive regulation of hydrolase activityGO:00513451480.013
activation of nf kappab inducing kinase activityGO:000725040.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
positive regulation of cellular catabolic processGO:00313311480.013
forebrain developmentGO:00309003020.013
cardiocyte differentiationGO:0035051870.013
regulation of cellular catabolic processGO:00313292420.013
sensory perception of mechanical stimulusGO:00509541070.013
multicellular organism growthGO:00352641610.013
nucleotide metabolic processGO:00091173320.013
cellular macromolecule catabolic processGO:00442652060.013
negative regulation of phosphate metabolic processGO:00459361840.013
nucleoside triphosphate metabolic processGO:00091412300.013
protein importGO:00170381010.013
transition metal ion transportGO:0000041380.013
leukocyte mediated cytotoxicityGO:0001909620.013
oocyte constructionGO:000730820.013
regulation of striated muscle cell differentiationGO:0051153810.013
negative regulation of peptidase activityGO:0010466460.013
Mouse
aminoglycan metabolic processGO:0006022340.013
negative regulation of odontogenesisGO:004248330.013
regulation of protein maturationGO:1903317960.013
Mouse
mesenchymal cell developmentGO:0014031930.013
regulation of ion transportGO:00432692150.013
homeostasis of number of cellsGO:00488722100.013
activation of mapk activityGO:0000187590.013
negative regulation of protein modification processGO:00314001630.013
protein oligomerizationGO:0051259670.012
positive regulation of t cell mediated cytotoxicityGO:0001916150.012
palate developmentGO:0060021760.012
multicellular organismal signalingGO:0035637910.012
positive regulation of innate immune responseGO:0045089800.012
regulation of transferase activityGO:00513382630.012
leukocyte chemotaxisGO:0030595690.012
cellular glucan metabolic processGO:0006073320.012
regulation of multi organism processGO:00439001110.012
mitotic cell cycle processGO:19030471590.012
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.012
cell matrix adhesionGO:0007160680.012
regulation of purine nucleotide metabolic processGO:19005421690.012
regulation of cytoplasmic transportGO:19036491120.012
cellular response to hormone stimulusGO:00328701500.012
positive regulation of reactive oxygen species metabolic processGO:2000379110.012
lateral inhibitionGO:004633110.012
negative regulation of tooth mineralizationGO:007017110.012
endomembrane system organizationGO:00102561470.012
response to extracellular stimulusGO:00099911270.012
regulation of neuron deathGO:19012141340.012
regulation of wnt signaling pathwayGO:00301111230.012
skeletal muscle organ developmentGO:00605381630.012
regulation of neuron apoptotic processGO:00435231220.012
multicellular organismal macromolecule metabolic processGO:0044259190.012
Mouse
regulation of membrane potentialGO:00423911920.012
response to epidermal growth factorGO:007084940.012
cardiac chamber developmentGO:00032051080.012
regulation of glucose metabolic processGO:0010906600.012
fatty acid metabolic processGO:00066311210.012
regulation of protein localizationGO:00328802310.012
positive regulation of immune effector processGO:00026991070.012
inorganic ion transmembrane transportGO:00986602340.012
regulation of cellular response to growth factor stimulusGO:0090287820.012
cellular response to lipopolysaccharideGO:0071222770.012
stem cell differentiationGO:00488632680.012
response to drugGO:0042493750.012
nuclear transportGO:00511691390.012
limb developmentGO:00601731660.012
carbohydrate homeostasisGO:00335001280.012
inter male aggressive behaviorGO:000212130.012
regulation of cell killingGO:0031341400.012
regulation of cell motilityGO:20001452360.012
positive regulation of apoptotic processGO:00430652170.012
synaptic transmissionGO:00072683290.012
myeloid cell differentiationGO:00300992330.012
cation transportGO:00068123990.012
response to amino acidGO:0043200370.012
physiological cardiac muscle hypertrophyGO:000330130.011
neuron deathGO:00709971540.011
substrate adhesion dependent cell spreadingGO:0034446300.011
positive regulation of cell killingGO:0031343330.011
positive regulation of cytokine productionGO:00018191740.011
Mouse
smoothened signaling pathwayGO:00072241050.011
regulation of macrophage migration inhibitory factor signaling pathwayGO:200044610.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
positive regulation of cell deathGO:00109422240.011
regulation of fatty acid metabolic processGO:0019217280.011
neutral lipid metabolic processGO:0006638570.011
regulation of nucleotide metabolic processGO:00061401690.011
hepaticobiliary system developmentGO:0061008670.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
fatty acid oxidationGO:0019395280.011
nucleocytoplasmic transportGO:00069131390.011
muscle cell developmentGO:00550011330.011
morphogenesis of a branching epitheliumGO:00611381930.011
monosaccharide transportGO:0015749580.011
regulation of blood pressureGO:0008217930.011
Mouse
carboxylic acid biosynthetic processGO:0046394860.011
leukocyte migrationGO:00509001240.011
organophosphate biosynthetic processGO:00904071220.011
negative regulation of protein phosphorylationGO:00019331260.011
monosaccharide biosynthetic processGO:0046364440.011
epithelial tube formationGO:00721751300.011
positive regulation of proteolysisGO:0045862850.011
cardiac muscle tissue developmentGO:00487381300.011
negative regulation of epithelial cell proliferationGO:0050680640.011
single organism cell adhesionGO:00986021560.011
purine ribonucleotide metabolic processGO:00091502900.011
diterpenoid metabolic processGO:0016101240.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
i kappab kinase nf kappab signalingGO:0007249850.011
detection of stimulusGO:0051606840.011
glycoprotein biosynthetic processGO:0009101890.011
protein localization to nucleusGO:00345041210.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
regulation of cardiac muscle hypertrophyGO:0010611130.010
regulation of membrane protein ectodomain proteolysisGO:005104330.010
protein kinase b signalingGO:0043491740.010
protein modification by small protein conjugation or removalGO:00706472070.010
protein catabolic processGO:00301632210.010
negative regulation of cell developmentGO:00107211690.010
positive regulation of mapk cascadeGO:00434101700.010
proteoglycan biosynthetic processGO:0030166200.010
negative regulation of nervous system developmentGO:00519611560.010
glycosylationGO:0070085620.010
positive regulation of cellular component biogenesisGO:0044089940.010
myeloid leukocyte migrationGO:0097529570.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.010
positive regulation of protein transportGO:0051222930.010
positive regulation of protein kinase activityGO:00458601440.010
hexose transportGO:0008645560.010
carbohydrate derivative catabolic processGO:19011362310.010
triglyceride metabolic processGO:0006641510.010
insulin metabolic processGO:190114230.010
cellular response to oxidative stressGO:0034599760.010
embryonic limb morphogenesisGO:00303261260.010
positive regulation of neuron differentiationGO:00456661410.010
insulin processingGO:003007020.010

Serpinf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.095
Human
musculoskeletal system diseaseDOID:1700.095
Human
bone diseaseDOID:008000100.053
Human
connective tissue diseaseDOID:6500.053
Human
bone development diseaseDOID:008000600.053
Human
osteochondrodysplasiaDOID:225600.035
Human
disease of metabolismDOID:001466700.033
inherited metabolic disorderDOID:65500.033
muscle tissue diseaseDOID:6600.027
muscular diseaseDOID:008000000.027
myopathyDOID:42300.025
nervous system diseaseDOID:86300.024
heart diseaseDOID:11400.019
cardiomyopathyDOID:005070000.019
cardiovascular system diseaseDOID:128700.019
lipid metabolism disorderDOID:314600.015
intrinsic cardiomyopathyDOID:006003600.014
immune system diseaseDOID:291400.014
sensory system diseaseDOID:005015500.010
eye and adnexa diseaseDOID:149200.010
eye diseaseDOID:561400.010