Mus musculus

287 known processes

Pnp

purine-nucleoside phosphorylase

(Aliases: AU015798,Pnp1,Np,AL024301,Np-1,Np-2)

Pnp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heterocycle catabolic processGO:00467002800.242
cellular ketone metabolic processGO:0042180840.164
cellular lipid metabolic processGO:00442553230.138
regulation of cellular amino acid metabolic processGO:000652150.120
regulation of hydrolase activityGO:00513362460.117
ribose phosphate metabolic processGO:00196932910.115
cellular amino acid metabolic processGO:00065201030.109
regulation of cellular catabolic processGO:00313292420.107
oxidation reduction processGO:00551143420.105
cellular amine metabolic processGO:0044106440.104
nucleotide metabolic processGO:00091173320.100
proteolysis involved in cellular protein catabolic processGO:00516031470.094
organic cyclic compound catabolic processGO:19013612950.091
myeloid cell differentiationGO:00300992330.089
protein importGO:00170381010.082
aromatic compound catabolic processGO:00194392860.079
lymphocyte proliferationGO:00466511640.079
cellular response to lipopolysaccharideGO:0071222770.078
positive regulation of proteolysisGO:0045862850.076
cation transportGO:00068123990.076
amine metabolic processGO:0009308450.073
neuron apoptotic processGO:00514021420.071
purine containing compound catabolic processGO:00725232130.071
regulation of apoptotic signaling pathwayGO:20012331970.070
regulation of proteolysisGO:00301621640.068
regulation of cellular ketone metabolic processGO:0010565660.068
immune effector processGO:00022523210.068
regulation of cellular amine metabolic processGO:0033238200.067
cellular modified amino acid metabolic processGO:0006575630.067
positive regulation of cellular amine metabolic processGO:003324050.067
negative regulation of molecular functionGO:00440922580.065
apoptotic signaling pathwayGO:00971903060.065
cell type specific apoptotic processGO:00972852680.062
organophosphate biosynthetic processGO:00904071220.061
i kappab kinase nf kappab signalingGO:0007249850.059
response to nutrient levelsGO:00316671090.059
regulation of ion transmembrane transportGO:00347651190.059
small molecule biosynthetic processGO:00442831320.056
cellular homeostasisGO:00197252400.056
purine ribonucleoside catabolic processGO:00461302050.054
response to oxidative stressGO:00069791230.054
ion transmembrane transportGO:00342203610.054
response to lipopolysaccharideGO:00324961280.053
positive regulation of cellular catabolic processGO:00313311480.053
inflammatory responseGO:00069542440.052
epidermis developmentGO:00085441870.050
regulation of membrane potentialGO:00423911920.048
glycerolipid metabolic processGO:00464861220.048
regulation of cellular response to stressGO:00801351590.047
response to organic cyclic compoundGO:00140701980.047
neuron deathGO:00709971540.047
regulation of cell activationGO:00508652890.046
protein catabolic processGO:00301632210.046
organic hydroxy compound metabolic processGO:19016152030.046
nucleoside triphosphate metabolic processGO:00091412300.044
muscle cell differentiationGO:00426922610.044
homeostasis of number of cellsGO:00488722100.043
sensory perceptionGO:00076002450.043
positive regulation of cellular amino acid metabolic processGO:004576430.042
glycosyl compound catabolic processGO:19016582060.041
membrane organizationGO:00610242450.041
purine containing compound metabolic processGO:00725213110.041
cellular protein catabolic processGO:00442571550.040
nucleoside triphosphate catabolic processGO:00091432050.040
nadph regenerationGO:000674020.039
nucleoside metabolic processGO:00091162460.039
gland developmentGO:00487323300.039
carbohydrate biosynthetic processGO:0016051740.039
monocarboxylic acid metabolic processGO:00327871910.038
cellular response to dna damage stimulusGO:00069742070.038
actin cytoskeleton organizationGO:00300362200.038
response to molecule of bacterial originGO:00022371430.038
extracellular structure organizationGO:00430621480.038
placenta developmentGO:00018901400.037
regulation of leukocyte differentiationGO:19021051590.037
regulation of kinase activityGO:00435492490.036
protein maturationGO:00516041760.036
nucleoside phosphate catabolic processGO:19012922220.036
sequestering of metal ionGO:0051238190.036
hexose catabolic processGO:001932030.035
purine nucleotide catabolic processGO:00061952110.035
organonitrogen compound catabolic processGO:19015652640.035
cellular protein complex assemblyGO:00436231160.035
macromolecule catabolic processGO:00090572810.035
triglyceride metabolic processGO:0006641510.035
modification dependent protein catabolic processGO:00199411330.035
dna metabolic processGO:00062593030.034
positive regulation of protein modification processGO:00314012990.034
positive regulation of peptidase activityGO:0010952490.034
spermatogenesisGO:00072832840.034
regulation of defense responseGO:00313472330.033
purine ribonucleoside metabolic processGO:00461282410.033
negative regulation of cellular protein metabolic processGO:00322692470.032
positive regulation of programmed cell deathGO:00430682180.032
blood circulationGO:00080151950.032
multicellular organism growthGO:00352641610.032
maintenance of locationGO:0051235890.032
cellular macromolecule catabolic processGO:00442652060.031
peptidyl amino acid modificationGO:00181933360.031
regulation of transmembrane transportGO:00347621280.031
sulfur compound metabolic processGO:00067901000.031
ribonucleotide catabolic processGO:00092612080.030
rho protein signal transductionGO:0007266320.030
carbohydrate metabolic processGO:00059752300.030
regulation of peptidase activityGO:0052547960.029
cellular response to hormone stimulusGO:00328701500.029
male gamete generationGO:00482322850.029
leukocyte mediated immunityGO:00024431740.029
protein localization to nucleusGO:00345041210.028
negative regulation of apoptotic signaling pathwayGO:20012341040.028
guanosine containing compound metabolic processGO:19010681440.028
amide transportGO:00428861380.028
acylglycerol metabolic processGO:0006639550.028
regulation of ion transportGO:00432692150.028
peptidyl tyrosine modificationGO:00182121450.028
negative regulation of cellular amine metabolic processGO:003323910.027
regulation of purine nucleotide catabolic processGO:00331211220.027
nitrogen compound transportGO:00717052710.027
nucleoside catabolic processGO:00091642060.027
small gtpase mediated signal transductionGO:0007264970.027
cellular response to lipidGO:00713961450.027
regulation of protein kinase activityGO:00458592320.027
t cell differentiationGO:00302171740.027
response to organonitrogen compoundGO:00102432460.027
purine ribonucleotide catabolic processGO:00091542080.027
transmembrane transportGO:00550854120.026
leukocyte differentiationGO:00025213420.026
regulation of purine nucleotide metabolic processGO:19005421690.026
cellular response to cytokine stimulusGO:00713451890.026
negative regulation of immune system processGO:00026832090.026
purine nucleoside catabolic processGO:00061522050.026
negative regulation of cell proliferationGO:00082852960.026
cofactor metabolic processGO:0051186800.026
Human
regulation of mapk cascadeGO:00434082480.025
ribonucleotide metabolic processGO:00092592910.025
reactive oxygen species metabolic processGO:0072593840.025
negative regulation of cellular amino acid metabolic processGO:004576300.025
nucleoside phosphate metabolic processGO:00067533380.025
skin developmentGO:00435882200.024
negative regulation of cell activationGO:00508661110.024
lipid localizationGO:00108761260.024
calcium ion transportGO:00068161590.024
epithelial tube morphogenesisGO:00605623030.024
carboxylic acid biosynthetic processGO:0046394860.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
positive regulation of secretion by cellGO:19035321140.024
cellular nitrogen compound catabolic processGO:00442702800.024
cellular response to molecule of bacterial originGO:0071219830.024
glycosyl compound metabolic processGO:19016572460.024
nucleotide catabolic processGO:00091662170.023
multicellular organismal homeostasisGO:00488711640.023
cation homeostasisGO:00550802120.023
cytoplasmic transportGO:00164822340.023
organonitrogen compound biosynthetic processGO:19015661920.023
peptide transportGO:00158331330.023
inorganic ion transmembrane transportGO:00986602340.023
sensory organ morphogenesisGO:00905962420.023
ribonucleoside catabolic processGO:00424542060.023
nucleobase containing small molecule metabolic processGO:00550863520.023
regulation of transferase activityGO:00513382630.023
intracellular protein transportGO:00068862040.023
defense response to other organismGO:00985421970.023
lipid biosynthetic processGO:00086101790.023
purine ribonucleoside triphosphate metabolic processGO:00092052200.022
superoxide metabolic processGO:0006801270.022
response to acid chemicalGO:00011011110.022
regulation of metal ion transportGO:00109591060.022
regulation of reactive oxygen species metabolic processGO:2000377400.022
calcium ion homeostasisGO:00550741270.022
cellular response to biotic stimulusGO:0071216920.022
guanosine containing compound catabolic processGO:19010691440.022
purine nucleoside triphosphate metabolic processGO:00091442260.022
regulation of secretion by cellGO:19035302490.022
positive regulation of apoptotic processGO:00430652170.022
protein localization to organelleGO:00333651850.021
multicellular organismal signalingGO:0035637910.021
ras protein signal transductionGO:0007265770.021
positive regulation of nucleoside metabolic processGO:0045979910.021
regulation of protein import into nucleusGO:0042306520.021
regulation of neuron deathGO:19012141340.021
stress activated mapk cascadeGO:0051403800.021
anion transportGO:00068201770.021
angiogenesisGO:00015252010.021
regulation of intracellular transportGO:00323861590.021
regulation of nucleotide metabolic processGO:00061401690.021
endocytosisGO:00068971680.021
vesicle organizationGO:0016050600.020
regulation of response to woundingGO:19030341890.020
posttranscriptional regulation of gene expressionGO:00106081550.020
pentose phosphate shuntGO:000609820.020
protein localization to membraneGO:00726571080.020
purine nucleotide metabolic processGO:00061633020.020
regulation of blood pressureGO:0008217930.020
regulation of cytoplasmic transportGO:19036491120.020
circulatory system processGO:00030131970.020
regulation of lipid biosynthetic processGO:0046890540.020
regulation of organelle organizationGO:00330432890.020
regulation of protein localizationGO:00328802310.020
ossificationGO:00015032160.020
extracellular matrix organizationGO:00301981470.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
regulation of endopeptidase activityGO:0052548890.020
nuclear transportGO:00511691390.020
regulation of multi organism processGO:00439001110.019
cellular chemical homeostasisGO:00550822150.019
response to extracellular stimulusGO:00099911270.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
t cell proliferationGO:00420981200.019
cellular metal ion homeostasisGO:00068751510.019
positive regulation of purine nucleotide metabolic processGO:19005441140.019
regulation of cytokine productionGO:00018172660.019
regulation of tube sizeGO:0035150570.019
cellular response to extracellular stimulusGO:0031668810.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
nuclear importGO:0051170950.019
positive regulation of endopeptidase activityGO:0010950430.019
signal transduction in absence of ligandGO:0038034550.019
erythrocyte differentiationGO:0030218880.019
positive regulation of cell deathGO:00109422240.019
development of primary male sexual characteristicsGO:0046546880.019
carbohydrate homeostasisGO:00335001280.019
purine nucleoside metabolic processGO:00422782410.019
carboxylic acid catabolic processGO:0046395510.019
organic anion transportGO:00157111370.018
g protein coupled receptor signaling pathwayGO:00071862430.018
peptide metabolic processGO:0006518460.018
action potentialGO:0001508780.018
carbohydrate derivative catabolic processGO:19011362310.018
regulation of actin filament based processGO:0032970990.018
regulation of nucleotide catabolic processGO:00308111220.018
alcohol metabolic processGO:00060661160.018
regulation of lipid metabolic processGO:00192161180.018
establishment of protein localization to organelleGO:00725941180.018
cellular amide metabolic processGO:0043603580.018
myeloid leukocyte differentiationGO:00025731190.018
positive regulation of hydrolase activityGO:00513451480.018
myeloid cell homeostasisGO:00022621140.018
regulation of protein serine threonine kinase activityGO:00719001570.018
lipid transportGO:0006869980.018
regulation of anatomical structure sizeGO:00900661780.018
negative regulation of protein phosphorylationGO:00019331260.018
plasma membrane organizationGO:0007009900.018
steroid metabolic processGO:00082021190.017
organic acid catabolic processGO:0016054510.017
monosaccharide biosynthetic processGO:0046364440.017
striated muscle tissue developmentGO:00147062930.017
negative regulation of intracellular signal transductionGO:19025321670.017
hair follicle developmentGO:0001942850.017
skeletal system developmentGO:00015013560.017
organophosphate catabolic processGO:00464342320.017
purine ribonucleotide metabolic processGO:00091502900.017
regulation of transcription factor import into nucleusGO:0042990240.017
extrinsic apoptotic signaling pathwayGO:00971911260.017
pyridine nucleotide biosynthetic processGO:001936340.017
Human
respiratory system developmentGO:00605411900.017
cellular response to oxidative stressGO:0034599760.017
morphogenesis of a branching structureGO:00017632030.017
protein processingGO:00164851630.017
negative regulation of lymphocyte activationGO:0051250910.016
hexose metabolic processGO:0019318980.016
respiratory tube developmentGO:00303231670.016
camera type eye developmentGO:00430102660.016
cellular response to thyroid hormone stimulusGO:009706710.016
regulation of cell motilityGO:20001452360.016
positive regulation of secretionGO:00510471300.016
divalent metal ion transportGO:00708381720.016
regulation of ossificationGO:00302781120.016
cellular ion homeostasisGO:00068731650.016
substantia nigra developmentGO:002176220.016
single organism nuclear importGO:1902593950.016
microtubule based processGO:00070172360.016
neural tube developmentGO:00219151600.016
nicotinamide nucleotide biosynthetic processGO:001935940.016
Human
lymphocyte mediated immunityGO:00024491390.016
ribose phosphate biosynthetic processGO:0046390590.016
stress activated protein kinase signaling cascadeGO:0031098810.016
organic hydroxy compound biosynthetic processGO:1901617770.016
negative regulation of t cell activationGO:0050868650.016
ribonucleoside metabolic processGO:00091192450.016
cation transmembrane transportGO:00986552660.016
regulation of protein targetingGO:1903533610.016
meiotic cell cycleGO:00513211220.015
metal ion homeostasisGO:00550651890.015
wnt signaling pathwayGO:00160551880.015
positive regulation of t helper 1 cell differentiationGO:004562740.015
cellular response to organonitrogen compoundGO:00714171450.015
response to hydroperoxideGO:003319460.015
regulation of vesicle mediated transportGO:00606271390.015
regulation of t cell activationGO:00508631700.015
anatomical structure homeostasisGO:00602491450.015
retina development in camera type eyeGO:00600411190.015
primitive erythrocyte differentiationGO:006031930.015
tissue homeostasisGO:00018941150.015
regulation of homeostatic processGO:00328441820.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
positive regulation of response to woundingGO:1903036660.015
regulation of protein transportGO:00512231630.015
b cell activationGO:00421131610.015
positive regulation of purine nucleotide catabolic processGO:0033123880.015
regulation of neuron apoptotic processGO:00435231220.015
regulation of protein catabolic processGO:00421761080.015
anion transmembrane transportGO:0098656710.015
endomembrane system organizationGO:00102561470.015
nucleocytoplasmic transportGO:00069131390.015
maternal process involved in female pregnancyGO:0060135320.015
carbohydrate derivative biosynthetic processGO:19011371830.015
protein polymerizationGO:0051258570.015
cytosolic calcium ion homeostasisGO:0051480700.015
positive regulation of mapk cascadeGO:00434101700.015
t cell activationGO:00421102890.015
protein targetingGO:00066051430.015
muscle system processGO:00030121410.015
negative regulation of phosphorus metabolic processGO:00105631840.015
sterol metabolic processGO:0016125580.015
regulation of nucleoside metabolic processGO:00091181300.015
multi multicellular organism processGO:00447061090.015
regulation of system processGO:00440572000.015
hair cycleGO:0042633900.015
inorganic cation transmembrane transportGO:00986622070.015
negative regulation of protein modification processGO:00314001630.015
development of primary sexual characteristicsGO:00451371430.015
lymphocyte differentiationGO:00300982420.014
er nucleus signaling pathwayGO:0006984270.014
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.014
response to peptide hormoneGO:00434341270.014
regulation of peptide transportGO:0090087910.014
fat soluble vitamin biosynthetic processGO:004236240.014
regulation of secretionGO:00510462740.014
innate immune responseGO:00450871570.014
Worm
nucleotide biosynthetic processGO:0009165780.014
regulation of cell migrationGO:00303342190.014
leukocyte proliferationGO:00706611720.014
cellular response to peptideGO:1901653920.014
regulation of peptidyl tyrosine phosphorylationGO:0050730930.014
neutral lipid metabolic processGO:0006638570.014
transcription factor import into nucleusGO:0042991260.014
cytokine productionGO:00018163190.014
Human
cellular divalent inorganic cation homeostasisGO:00725031270.014
regulation of epithelial cell proliferationGO:00506781410.014
autophagyGO:0006914450.014
regulation of inflammatory responseGO:00507271470.014
retrograde transport endosome to golgiGO:004214720.014
transmission of nerve impulseGO:0019226760.014
protein import into nucleusGO:0006606950.014
response to inorganic substanceGO:0010035960.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
stem cell differentiationGO:00488632680.013
mapk cascadeGO:00001652810.013
forebrain developmentGO:00309003020.013
blood vessel morphogenesisGO:00485142850.013
sensory perception of mechanical stimulusGO:00509541070.013
gtp metabolic processGO:00460391440.013
l ascorbic acid metabolic processGO:001985240.013
regulation of establishment of protein localizationGO:00702011810.013
positive regulation of ion transportGO:0043270650.013
epithelial cell proliferationGO:00506731740.013
morphogenesis of embryonic epitheliumGO:00163311590.013
regulation of endocytosisGO:0030100690.013
developmental maturationGO:00217001930.013
positive regulation of transferase activityGO:00513471670.013
rhythmic processGO:00485111740.013
organelle fissionGO:00482851700.013
response to temperature stimulusGO:0009266550.013
synaptic transmissionGO:00072683290.013
viral life cycleGO:0019058360.013
peptidyl serine modificationGO:0018209830.013
fat cell differentiationGO:00454441600.013
lung developmentGO:00303241640.013
cell activation involved in immune responseGO:00022631260.013
cellular carbohydrate metabolic processGO:00442621190.013
peptidyl serine phosphorylationGO:0018105740.013
purine containing compound biosynthetic processGO:0072522700.013
notochord cell developmentGO:006003510.013
epithelial cell developmentGO:00020641590.013
vascular process in circulatory systemGO:0003018620.013
regulation of blood vessel sizeGO:0050880560.012
divalent inorganic cation homeostasisGO:00725071380.012
response to topologically incorrect proteinGO:0035966250.012
regulation of actin cytoskeleton organizationGO:0032956840.012
blastocyst developmentGO:0001824800.012
glucose homeostasisGO:00425931280.012
generation of precursor metabolites and energyGO:00060911030.012
positive regulation of protein kinase activityGO:00458601440.012
response to radiationGO:00093141650.012
gonad developmentGO:00084061410.012
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.012
regulation of intracellular protein transportGO:0033157820.012
monocarboxylic acid biosynthetic processGO:0072330610.012
regulation of cell projection organizationGO:00313442060.012
response to growth factorGO:00708481980.012
small molecule catabolic processGO:0044282710.012
muscle tissue developmentGO:00605373080.012
fatty acid metabolic processGO:00066311210.012
mitotic cell cycleGO:00002781950.012
positive regulation of nucleotide metabolic processGO:00459811140.012
cellular response to topologically incorrect proteinGO:0035967250.012
regulation of ras protein signal transductionGO:00465781140.012
neural tube formationGO:00018411080.012
wound healingGO:00420601570.012
negative regulation of protein maturationGO:1903318790.012
positive regulation of organelle organizationGO:00106381280.012
t cell mediated cytotoxicityGO:0001913260.012
thymus developmentGO:0048538410.011
adaptive immune responseGO:00022501550.011
skeletal muscle organ developmentGO:00605381630.011
developmental growth involved in morphogenesisGO:00605601380.011
nuclear divisionGO:00002801580.011
actin polymerization or depolymerizationGO:0008154540.011
glucose metabolic processGO:0006006920.011
heart contractionGO:0060047930.011
response to oxygen radicalGO:0000305160.011
organic acid biosynthetic processGO:0016053860.011
purine nucleoside biosynthetic processGO:0042451190.011
monosaccharide metabolic processGO:00059961060.011
cellular response to organic cyclic compoundGO:0071407870.011
striated muscle cell developmentGO:00550021250.011
interleukin 8 productionGO:003263740.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
regulation of myeloid cell differentiationGO:0045637960.011
gtp catabolic processGO:00061841430.011
mitotic cytokinesisGO:000028140.011
regulation of neuron differentiationGO:00456642810.011
plasma membrane long chain fatty acid transportGO:001591110.011
water soluble vitamin biosynthetic processGO:004236430.011
positive regulation of protein phosphorylationGO:00019342420.011
cytokinetic processGO:003250620.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
negative regulation of phosphate metabolic processGO:00459361840.011
regulation of immunological synapse formationGO:200052020.011
cell substrate adhesionGO:00315891300.011
positive regulation of kinase activityGO:00336741550.011
male sex differentiationGO:00466611090.011
embryonic epithelial tube formationGO:00018381300.011
alpha amino acid metabolic processGO:1901605590.011
response to insulinGO:00328681000.011
positive regulation of transmembrane transportGO:0034764290.011
glycoprotein metabolic processGO:00091001160.011
regulation of wnt signaling pathwayGO:00301111230.011
purine ribonucleotide biosynthetic processGO:0009152590.011
branching morphogenesis of an epithelial tubeGO:00487541590.011
eosinophil migrationGO:007267730.011
negative regulation of protein metabolic processGO:00512482820.011
inflammatory response to antigenic stimulusGO:0002437300.011
divalent inorganic cation transportGO:00725111780.010
removal of superoxide radicalsGO:0019430120.010
engulfment of apoptotic cellGO:004365230.010
pigment biosynthetic processGO:0046148260.010
positive regulation of nucleotide catabolic processGO:0030813880.010
jnk cascadeGO:0007254720.010
negative regulation of transferase activityGO:0051348850.010
regulation of body fluid levelsGO:00508781620.010
pigment metabolic processGO:0042440320.010
regulation of hormone levelsGO:00108172110.010
methylationGO:00322591340.010
regulation of lymphocyte activationGO:00512492400.010
olfactory learningGO:000835520.010
positive regulation of lymphocyte activationGO:00512511400.010
response to reactive oxygen speciesGO:0000302560.010
dendrite developmentGO:00163581150.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.010
negative regulation of leukocyte differentiationGO:1902106510.010
regulation of interleukin 8 productionGO:003267730.010
pentose metabolic processGO:001932150.010
response to thyroid hormoneGO:009706620.010
positive regulation of cytosolic calcium ion concentrationGO:0007204650.010
cytosolic calcium ion transportGO:0060401480.010
regulation of leukocyte apoptotic processGO:2000106560.010
peptidyl tyrosine phosphorylationGO:00181081430.010

Pnp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
Human
immune system diseaseDOID:291400.040
Human
cancerDOID:16200.037
disease of cellular proliferationDOID:1456600.037
nervous system diseaseDOID:86300.029
organ system cancerDOID:005068600.014
musculoskeletal system diseaseDOID:1700.013
connective tissue diseaseDOID:6500.013
neuropathyDOID:87000.012
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
hematologic cancerDOID:253100.010
immune system cancerDOID:006008300.010