Mus musculus

0 known processes

Arhgef18

rho/rac guanine nucleotide exchange factor (GEF) 18

(Aliases: D030053O22Rik,AI467246)

Arhgef18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular nitrogen compound catabolic processGO:00442702800.077
Human Mouse
ribonucleotide catabolic processGO:00092612080.075
Human Mouse
nucleobase containing small molecule metabolic processGO:00550863520.073
Human Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.066
Human Mouse
ras protein signal transductionGO:0007265770.063
Mouse
purine nucleoside triphosphate catabolic processGO:00091462030.060
Human Mouse
small gtpase mediated signal transductionGO:0007264970.060
Human Mouse
glycosyl compound catabolic processGO:19016582060.059
Human Mouse
nucleoside phosphate catabolic processGO:19012922220.056
Human Mouse
nucleotide metabolic processGO:00091173320.055
Human Mouse
purine ribonucleoside catabolic processGO:00461302050.055
Human Mouse
negative regulation of molecular functionGO:00440922580.052
organic cyclic compound catabolic processGO:19013612950.051
Human Mouse
nucleoside phosphate metabolic processGO:00067533380.051
Human Mouse
regulation of cell projection organizationGO:00313442060.051
actin cytoskeleton organizationGO:00300362200.051
Human Mouse
purine ribonucleoside triphosphate metabolic processGO:00092052200.048
Human Mouse
regulation of hydrolase activityGO:00513362460.048
Human Mouse
positive regulation of purine nucleotide metabolic processGO:19005441140.047
Human Mouse
organophosphate catabolic processGO:00464342320.047
Human Mouse
purine nucleotide metabolic processGO:00061633020.047
Human Mouse
regulation of purine nucleotide metabolic processGO:19005421690.046
Human Mouse
nucleoside metabolic processGO:00091162460.046
Human Mouse
protein modification by small protein conjugationGO:00324461870.046
amine metabolic processGO:0009308450.045
rho protein signal transductionGO:0007266320.045
Mouse
regulation of cellular amino acid metabolic processGO:000652150.045
nucleoside triphosphate metabolic processGO:00091412300.045
Human Mouse
regulation of cellular catabolic processGO:00313292420.045
Human Mouse
nucleotide catabolic processGO:00091662170.044
Human Mouse
purine containing compound catabolic processGO:00725232130.043
Human Mouse
regulation of organelle organizationGO:00330432890.042
cellular amine metabolic processGO:0044106440.042
purine ribonucleotide metabolic processGO:00091502900.042
Human Mouse
glycosyl compound metabolic processGO:19016572460.041
Human Mouse
purine nucleoside catabolic processGO:00061522050.041
Human Mouse
nucleoside catabolic processGO:00091642060.041
Human Mouse
regulation of cellular amine metabolic processGO:0033238200.041
protein ubiquitinationGO:00165671710.041
ribonucleoside triphosphate catabolic processGO:00092031990.040
Human Mouse
regulation of nucleoside metabolic processGO:00091181300.040
Human Mouse
purine containing compound metabolic processGO:00725213110.039
Human Mouse
regulation of cellular ketone metabolic processGO:0010565660.038
cellular amino acid metabolic processGO:00065201030.038
purine nucleoside triphosphate metabolic processGO:00091442260.037
Human Mouse
purine nucleoside metabolic processGO:00422782410.037
Human Mouse
negative regulation of cellular component organizationGO:00511291940.036
organonitrogen compound catabolic processGO:19015652640.036
Human Mouse
organelle localizationGO:00516401790.036
Mouse
ribonucleotide metabolic processGO:00092592910.036
Human Mouse
regulation of gtp catabolic processGO:00331241130.036
Human Mouse
heterocycle catabolic processGO:00467002800.035
Human Mouse
negative regulation of cellular protein metabolic processGO:00322692470.035
purine nucleotide catabolic processGO:00061952110.035
Human Mouse
regulation of neuron projection developmentGO:00109751690.035
ribonucleoside triphosphate metabolic processGO:00091992200.035
Human Mouse
purine ribonucleoside metabolic processGO:00461282410.035
Human Mouse
aromatic compound catabolic processGO:00194392860.034
Human Mouse
cellular ketone metabolic processGO:0042180840.034
macromolecule catabolic processGO:00090572810.034
ribose phosphate metabolic processGO:00196932910.034
Human Mouse
ribonucleoside metabolic processGO:00091192450.033
Human Mouse
positive regulation of nucleotide metabolic processGO:00459811140.033
Human Mouse
intracellular protein transportGO:00068862040.032
carbohydrate derivative catabolic processGO:19011362310.032
Human Mouse
ribonucleoside catabolic processGO:00424542060.032
Human Mouse
positive regulation of nucleotide catabolic processGO:0030813880.032
Human Mouse
ion transmembrane transportGO:00342203610.032
cellular lipid metabolic processGO:00442553230.031
protein localization to organelleGO:00333651850.031
negative regulation of cell developmentGO:00107211690.031
Mouse
regulation of anatomical structure sizeGO:00900661780.030
regulation of vesicle mediated transportGO:00606271390.030
positive regulation of hydrolase activityGO:00513451480.030
Human Mouse
regulation of neuron differentiationGO:00456642810.030
negative regulation of protein metabolic processGO:00512482820.030
cation transportGO:00068123990.029
endomembrane system organizationGO:00102561470.029
regulation of membrane potentialGO:00423911920.029
microtubule based processGO:00070172360.029
Mouse
histone modificationGO:00165701590.029
endocytosisGO:00068971680.029
nucleoside triphosphate catabolic processGO:00091432050.029
Human Mouse
guanosine containing compound metabolic processGO:19010681440.029
Human Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.029
transmembrane transportGO:00550854120.029
regulation of nucleotide metabolic processGO:00061401690.029
Human Mouse
cytokine productionGO:00018163190.028
regulation of purine nucleotide catabolic processGO:00331211220.028
Human Mouse
establishment of organelle localizationGO:00516561220.028
Mouse
organelle assemblyGO:00709251770.028
positive regulation of cellular catabolic processGO:00313311480.028
Human Mouse
regulation of protein kinase activityGO:00458592320.028
chromatin organizationGO:00063252060.028
positive regulation of cellular amine metabolic processGO:003324050.027
cellular homeostasisGO:00197252400.027
gtp catabolic processGO:00061841430.027
Human Mouse
mapk cascadeGO:00001652810.027
negative regulation of cellular amine metabolic processGO:003323910.027
protein modification by small protein conjugation or removalGO:00706472070.027
peptidyl amino acid modificationGO:00181933360.027
purine ribonucleotide catabolic processGO:00091542080.027
Human Mouse
synaptic transmissionGO:00072683290.027
sequestering of metal ionGO:0051238190.027
protein targetingGO:00066051430.027
regulation of kinase activityGO:00435492490.026
cell adhesionGO:00071553290.026
positive regulation of gtpase activityGO:0043547850.026
Human Mouse
membrane organizationGO:00610242450.026
regulation of nucleotide catabolic processGO:00308111220.025
Human Mouse
positive regulation of protein modification processGO:00314012990.025
cation transmembrane transportGO:00986552660.025
immune effector processGO:00022523210.025
maintenance of locationGO:0051235890.025
positive regulation of purine nucleotide catabolic processGO:0033123880.025
Human Mouse
regulation of cellular component biogenesisGO:00440871810.025
regulation of intracellular transportGO:00323861590.025
inorganic cation transmembrane transportGO:00986622070.025
negative regulation of protein modification processGO:00314001630.025
negative regulation of immune system processGO:00026832090.025
cellular macromolecule catabolic processGO:00442652060.025
apoptotic signaling pathwayGO:00971903060.024
positive regulation of cell developmentGO:00107202370.024
dna metabolic processGO:00062593030.024
positive regulation of ras gtpase activityGO:0032320650.024
Mouse
axonogenesisGO:00074092740.024
positive regulation of nucleoside metabolic processGO:0045979910.024
Human Mouse
covalent chromatin modificationGO:00165691630.024
cellular response to lipidGO:00713961450.024
regulation of cell morphogenesis involved in differentiationGO:00107691510.024
protein maturationGO:00516041760.023
regulation of cellular component sizeGO:00325351210.023
regulation of protein localizationGO:00328802310.023
cell growthGO:00160491300.022
gtp metabolic processGO:00460391440.022
Human Mouse
myeloid cell differentiationGO:00300992330.022
stem cell differentiationGO:00488632680.022
cellular chemical homeostasisGO:00550822150.022
negative regulation of protein phosphorylationGO:00019331260.022
leukocyte differentiationGO:00025213420.022
response to organonitrogen compoundGO:00102432460.022
plasma membrane organizationGO:0007009900.022
negative regulation of cell proliferationGO:00082852960.021
muscle cell differentiationGO:00426922610.021
negative regulation of nervous system developmentGO:00519611560.021
Mouse
inorganic ion transmembrane transportGO:00986602340.021
lipid localizationGO:00108761260.021
lipid biosynthetic processGO:00086101790.021
negative regulation of phosphorus metabolic processGO:00105631840.021
male gamete generationGO:00482322850.021
organonitrogen compound biosynthetic processGO:19015661920.021
cellular protein complex assemblyGO:00436231160.021
divalent inorganic cation transportGO:00725111780.021
innate immune responseGO:00450871570.021
actin filament organizationGO:00070151130.021
Mouse
compound eye developmentGO:004874910.020
cellular metal ion homeostasisGO:00068751510.020
protein processingGO:00164851630.020
divalent inorganic cation homeostasisGO:00725071380.020
guanosine containing compound catabolic processGO:19010691440.020
Human Mouse
homeostasis of number of cellsGO:00488722100.020
g protein coupled receptor signaling pathwayGO:00071862430.020
negative regulation of phosphate metabolic processGO:00459361840.020
cation homeostasisGO:00550802120.020
chemotaxisGO:00069352470.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.020
stem cell developmentGO:00488642190.020
metal ion homeostasisGO:00550651890.020
response to growth factorGO:00708481980.019
cell type specific apoptotic processGO:00972852680.019
ubiquitin dependent protein catabolic processGO:00065111290.019
cell divisionGO:00513011200.019
positive regulation of kinase activityGO:00336741550.019
negative regulation of intracellular signal transductionGO:19025321670.019
sequestering of calcium ionGO:0051208180.019
cellular ion homeostasisGO:00068731650.019
carbohydrate derivative biosynthetic processGO:19011371830.019
establishment of protein localization to organelleGO:00725941180.019
protein catabolic processGO:00301632210.019
t cell activationGO:00421102890.019
myosin filament assemblyGO:003103420.019
anatomical structure homeostasisGO:00602491450.019
gland developmentGO:00487323300.019
regulation of reactive oxygen species metabolic processGO:2000377400.018
protein localization to nucleusGO:00345041210.018
morphogenesis of embryonic epitheliumGO:00163311590.018
cellular response to organonitrogen compoundGO:00714171450.018
regulation of endocytosisGO:0030100690.018
reactive oxygen species metabolic processGO:0072593840.018
regulation of ras gtpase activityGO:0032318880.018
Mouse
engulfment of apoptotic cellGO:004365230.018
chromatin modificationGO:00165681870.018
ossificationGO:00015032160.018
macromolecule methylationGO:00434141200.018
positive regulation of programmed cell deathGO:00430682180.018
sensory perceptionGO:00076002450.018
cognitionGO:00508901490.018
regulation of mapk cascadeGO:00434082480.018
positive regulation of protein phosphorylationGO:00019342420.018
response to molecule of bacterial originGO:00022371430.018
regulation of transferase activityGO:00513382630.018
positive regulation of nervous system developmentGO:00519622210.018
negative regulation of cellular amino acid metabolic processGO:004576300.018
positive regulation of mapk cascadeGO:00434101700.018
divalent metal ion transportGO:00708381720.017
spermatogenesisGO:00072832840.017
myosin filament organizationGO:003103330.017
positive regulation of gtp catabolic processGO:0033126850.017
Human Mouse
cytoplasmic transportGO:00164822340.017
positive regulation of cell deathGO:00109422240.017
modification dependent protein catabolic processGO:00199411330.017
regulation of cytokine productionGO:00018172660.017
negative regulation of phosphorylationGO:00423261660.017
establishment or maintenance of cell polarityGO:0007163860.017
Mouse
response to inorganic substanceGO:0010035960.017
modification dependent macromolecule catabolic processGO:00436321330.017
regulation of ion transportGO:00432692150.017
regulation of cell motilityGO:20001452360.017
calcium ion homeostasisGO:00550741270.017
cellular protein catabolic processGO:00442571550.017
cellular response to biotic stimulusGO:0071216920.017
microtubule cytoskeleton organizationGO:00002261570.017
Mouse
blood vessel morphogenesisGO:00485142850.017
positive regulation of apoptotic processGO:00430652170.017
nitrogen compound transportGO:00717052710.017
proteolysis involved in cellular protein catabolic processGO:00516031470.016
regulation of actin cytoskeleton organizationGO:0032956840.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
regulation of feeding behaviorGO:006025930.016
nuclear transportGO:00511691390.016
nucleoside monophosphate metabolic processGO:0009123850.016
exocytosisGO:00068871210.016
regionalizationGO:00030023370.016
vesicle localizationGO:0051648860.016
asymmetric stem cell divisionGO:009872230.016
organelle fissionGO:00482851700.016
posttranscriptional regulation of gene expressionGO:00106081550.016
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.016
organophosphate biosynthetic processGO:00904071220.016
regulation of establishment of protein localizationGO:00702011810.016
regulation of proteolysisGO:00301621640.016
regulation of ras protein signal transductionGO:00465781140.016
Mouse
positive regulation of neuron differentiationGO:00456661410.016
respiratory system developmentGO:00605411900.016
response to organic cyclic compoundGO:00140701980.016
lymphocyte differentiationGO:00300982420.016
positive regulation of protein kinase activityGO:00458601440.015
positive regulation of cellular component biogenesisGO:0044089940.015
asymmetric neuroblast divisionGO:005505910.015
regulation of cell sizeGO:0008361720.015
regulation of apoptotic signaling pathwayGO:20012331970.015
regulation of cell activationGO:00508652890.015
striated muscle myosin thick filament assemblyGO:007168810.015
regulation of chromosome organizationGO:0033044830.015
mesodermal cell migrationGO:000807840.015
locomotory behaviorGO:00076261950.015
striated muscle tissue developmentGO:00147062930.015
multicellular organismal homeostasisGO:00488711640.015
regulation of cell cycleGO:00517262810.015
cellular divalent inorganic cation homeostasisGO:00725031270.015
regulation of cell adhesionGO:00301551540.015
vesicle organizationGO:0016050600.015
muscle tissue developmentGO:00605373080.015
muscle system processGO:00030121410.014
action potentialGO:0001508780.014
myeloid leukocyte activationGO:0002274830.014
cellular response to molecule of bacterial originGO:0071219830.014
regulation of neuron deathGO:19012141340.014
developmental maturationGO:00217001930.014
cellular response to growth factor stimulusGO:00713631970.014
positive regulation of transferase activityGO:00513471670.014
cellular response to cytokine stimulusGO:00713451890.014
neural precursor cell proliferationGO:00613511210.014
ribonucleoside monophosphate metabolic processGO:0009161800.014
skeletal system developmentGO:00015013560.014
skeletal muscle organ developmentGO:00605381630.014
regulation of body fluid levelsGO:00508781620.014
response to radiationGO:00093141650.014
germ cell developmentGO:00072811850.014
atp metabolic processGO:0046034750.014
cytokinetic processGO:003250620.014
regulation of cytoskeleton organizationGO:00514931220.014
protein alkylationGO:0008213810.014
regulation of homeostatic processGO:00328441820.014
cellular response to lipopolysaccharideGO:0071222770.014
anion transportGO:00068201770.014
forebrain developmentGO:00309003020.014
telencephalon developmentGO:00215371860.014
lung developmentGO:00303241640.014
glucose homeostasisGO:00425931280.014
regulation of system processGO:00440572000.014
organic hydroxy compound transportGO:0015850930.013
wound healingGO:00420601570.013
ameboidal type cell migrationGO:00016671280.013
developmental growth involved in morphogenesisGO:00605601380.013
transmission of nerve impulseGO:0019226760.013
nucleocytoplasmic transportGO:00069131390.013
response to lipopolysaccharideGO:00324961280.013
single organismal cell cell adhesionGO:00163371310.013
regulation of hormone levelsGO:00108172110.013
negative regulation of transferase activityGO:0051348850.013
regulation of cellular response to stressGO:00801351590.013
response to oxidative stressGO:00069791230.013
response to light stimulusGO:00094161350.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
protein importGO:00170381010.013
cellular component assembly involved in morphogenesisGO:00109271390.013
regulation of protein serine threonine kinase activityGO:00719001570.013
response to extracellular stimulusGO:00099911270.013
organic hydroxy compound metabolic processGO:19016152030.013
oxidation reduction processGO:00551143420.013
canonical wnt signaling pathwayGO:00600701300.013
regulation of cell growthGO:0001558910.013
stem cell maintenanceGO:00198271300.013
response to acid chemicalGO:00011011110.013
regulation of transmembrane transportGO:00347621280.013
learningGO:0007612980.013
regulation of secretion by cellGO:19035302490.013
tube formationGO:00351481400.013
methylationGO:00322591340.013
male genitalia morphogenesisGO:004880840.013
regulation of defense responseGO:00313472330.013
proteasomal protein catabolic processGO:0010498980.013
protein localization to plasma membraneGO:0072659570.012
spermatid differentiationGO:00485151150.012
fertilizationGO:00095661270.012
neuron deathGO:00709971540.012
mitotic cytokinesisGO:000028140.012
regulation of protein transportGO:00512231630.012
response to endoplasmic reticulum stressGO:0034976530.012
viral gene expressionGO:001908030.012
multicellular organism growthGO:00352641610.012
positive regulation of organelle organizationGO:00106381280.012
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.012
carbohydrate homeostasisGO:00335001280.012
dendrite developmentGO:00163581150.012
neural tube formationGO:00018411080.012
regulation of cell migrationGO:00303342190.012
nucleoside monophosphate catabolic processGO:0009125590.012
protein localization to membraneGO:00726571080.012
lipid homeostasisGO:0055088630.012
lipid transportGO:0006869980.012
wnt signaling pathwayGO:00160551880.012
cellular calcium ion homeostasisGO:00068741190.012
single organism cell adhesionGO:00986021560.012
protein methylationGO:0006479810.012
defecationGO:003042110.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
positive regulation of cytokine productionGO:00018191740.012
cell activation involved in immune responseGO:00022631260.012
protein polyubiquitinationGO:0000209330.012
regulation of ion transmembrane transportGO:00347651190.012
meiotic cell cycleGO:00513211220.012
leukocyte activation involved in immune responseGO:00023661260.012
regulation of map kinase activityGO:00434051200.012
monocarboxylic acid metabolic processGO:00327871910.012
cell substrate adhesionGO:00315891300.012
interleukin 8 productionGO:003263740.012
regulation of cytoplasmic transportGO:19036491120.012
cellular response to acid chemicalGO:0071229680.012
phospholipid metabolic processGO:0006644870.012
peptide transportGO:00158331330.012
glial cell differentiationGO:00100011310.012
t cell differentiationGO:00302171740.012
defense response to virusGO:0051607680.012
regulation of secretionGO:00510462740.012
calcium ion transportGO:00068161590.012
reactive nitrogen species metabolic processGO:200105700.012
embryonic epithelial tube formationGO:00018381300.011
regulation of protein catabolic processGO:00421761080.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
protein import into nucleusGO:0006606950.011
angiogenesisGO:00015252010.011
nuclear divisionGO:00002801580.011
regulation of actin filament based processGO:0032970990.011
hormone secretionGO:00468791280.011
regulation of interleukin 8 productionGO:003267730.011
camera type eye developmentGO:00430102660.011
negative regulation of organelle organizationGO:0010639900.011
oocyte axis specificationGO:000730920.011
regulation of sequence specific dna binding transcription factor activityGO:00510901060.011
actin filament polymerizationGO:0030041440.011
regulation of protein maturationGO:1903317960.011
respiratory tube developmentGO:00303231670.011
rab protein signal transductionGO:003248210.011
amide transportGO:00428861380.011
regulation of metal ion transportGO:00109591060.011
regulation of cell substrate adhesionGO:0010810730.011
skin developmentGO:00435882200.011
carbohydrate metabolic processGO:00059752300.011
positive regulation of neuron projection developmentGO:0010976790.011
regulation of lymphocyte activationGO:00512492400.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
multicellular organismal signalingGO:0035637910.011
digestive system developmentGO:00551232000.011
reactive oxygen species biosynthetic processGO:190340980.011
peptidyl tyrosine modificationGO:00182121450.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
learning or memoryGO:00076111480.011
inflammatory responseGO:00069542440.011
muscle adaptationGO:0043500390.011
neural tube developmentGO:00219151600.011
tissue homeostasisGO:00018941150.011
lateral inhibitionGO:004633110.011
extracellular matrix organizationGO:00301981470.011
blood circulationGO:00080151950.011
regulation of intracellular protein transportGO:0033157820.011
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.011
response to peptideGO:19016521360.011
protein polymerizationGO:0051258570.011
fatty acid metabolic processGO:00066311210.011
atp catabolic processGO:0006200550.011
cholesterol transportGO:0030301380.011
response to nutrient levelsGO:00316671090.011
glycoprotein metabolic processGO:00091001160.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
epithelial tube morphogenesisGO:00605623030.011
skeletal system morphogenesisGO:00487052030.011
dna repairGO:00062811070.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
b cell activationGO:00421131610.010
glycerolipid metabolic processGO:00464861220.010
intrinsic apoptotic signaling pathwayGO:00971931320.010
myotube differentiationGO:00149021050.010
development of primary sexual characteristicsGO:00451371430.010
regulation of cell cycle processGO:00105641600.010
cellular response to dna damage stimulusGO:00069742070.010
regulation of actin nucleationGO:005112540.010
nuclear importGO:0051170950.010
mitotic cell cycleGO:00002781950.010
Mouse
positive regulation of apoptotic signaling pathwayGO:2001235950.010
regulation of protein processingGO:0070613960.010
cellularizationGO:000734910.010
rhythmic processGO:00485111740.010
establishment of vesicle localizationGO:0051650810.010
cellular response to extracellular stimulusGO:0031668810.010
interspecies interaction between organismsGO:0044419830.010
positive regulation of innate immune responseGO:0045089800.010
cellular response to organic cyclic compoundGO:0071407870.010
localization within membraneGO:005166840.010
regulation of response to woundingGO:19030341890.010
establishment of protein localization to membraneGO:0090150540.010
epithelial tube formationGO:00721751300.010
positive regulation of cell activationGO:00508671580.010

Arhgef18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.030
disease of anatomical entityDOID:700.030
disease of metabolismDOID:001466700.018
central nervous system diseaseDOID:33100.017
immune system diseaseDOID:291400.016
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.012
organ system cancerDOID:005068600.012
musculoskeletal system diseaseDOID:1700.010
sensory system diseaseDOID:005015500.010