Mus musculus

57 known processes

Astl

astacin-like metalloendopeptidase (M12 family)

(Aliases: MGC76457,7420700F21,C87576)

Astl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cytokine productionGO:00018163190.103
regulation of cellular amino acid metabolic processGO:000652150.065
regulation of cytokine productionGO:00018172660.064
defense response to bacteriumGO:00427421190.064
cellular amino acid metabolic processGO:00065201030.062
inflammatory responseGO:00069542440.056
defense response to other organismGO:00985421970.048
regulation of cellular ketone metabolic processGO:0010565660.044
cellular amine metabolic processGO:0044106440.041
positive regulation of cellular amino acid metabolic processGO:004576430.041
amine metabolic processGO:0009308450.037
cellular ketone metabolic processGO:0042180840.036
lymphocyte differentiationGO:00300982420.035
positive regulation of cytokine productionGO:00018191740.035
dna metabolic processGO:00062593030.034
cation homeostasisGO:00550802120.034
leukocyte differentiationGO:00025213420.034
regulation of lymphocyte activationGO:00512492400.033
regulation of secretion by cellGO:19035302490.033
cation transmembrane transportGO:00986552660.032
cation transportGO:00068123990.032
small molecule biosynthetic processGO:00442831320.032
regulation of secretionGO:00510462740.031
organonitrogen compound catabolic processGO:19015652640.031
regulation of establishment of protein localizationGO:00702011810.031
cellular protein complex assemblyGO:00436231160.031
positive regulation of programmed cell deathGO:00430682180.030
regulation of ion transportGO:00432692150.030
regulation of cellular amine metabolic processGO:0033238200.030
cell activation involved in immune responseGO:00022631260.030
positive regulation of cellular amine metabolic processGO:003324050.030
nucleobase containing small molecule metabolic processGO:00550863520.029
interleukin 8 secretionGO:007260630.029
immune effector processGO:00022523210.029
apoptotic signaling pathwayGO:00971903060.028
regulation of defense responseGO:00313472330.028
heterocycle catabolic processGO:00467002800.028
t cell activationGO:00421102890.028
reactive oxygen species metabolic processGO:0072593840.027
sensory perceptionGO:00076002450.027
regulation of cell activationGO:00508652890.027
chemotaxisGO:00069352470.027
leukocyte activation involved in immune responseGO:00023661260.027
regulation of membrane potentialGO:00423911920.027
negative regulation of intracellular signal transductionGO:19025321670.026
g protein coupled receptor signaling pathwayGO:00071862430.026
leukocyte migrationGO:00509001240.025
response to molecule of bacterial originGO:00022371430.025
detection of molecule of bacterial originGO:003249020.025
t cell proliferationGO:00420981200.025
developmental growth involved in morphogenesisGO:00605601380.025
regulation of t cell activationGO:00508631700.025
regulation of interleukin 8 productionGO:003267730.024
inorganic cation transmembrane transportGO:00986622070.024
regulation of cell cycleGO:00517262810.024
leukocyte proliferationGO:00706611720.024
purine containing compound metabolic processGO:00725213110.024
gland developmentGO:00487323300.023
positive regulation of cell deathGO:00109422240.023
endocytosisGO:00068971680.023
homeostasis of number of cellsGO:00488722100.023
interleukin 8 productionGO:003263740.023
cell growthGO:00160491300.022
lymphocyte proliferationGO:00466511640.022
positive regulation of apoptotic processGO:00430652170.022
regulation of multi organism processGO:00439001110.021
calcitriol biosynthetic process from calciolGO:003637830.021
response to lipopolysaccharideGO:00324961280.021
purine nucleotide metabolic processGO:00061633020.021
t cell differentiationGO:00302171740.021
negative regulation of immune system processGO:00026832090.021
camera type eye developmentGO:00430102660.021
cellular nitrogen compound catabolic processGO:00442702800.020
protein ubiquitinationGO:00165671710.020
regulation of protein localizationGO:00328802310.020
transmembrane transportGO:00550854120.020
regulation of organelle organizationGO:00330432890.020
protein catabolic processGO:00301632210.020
striated muscle tissue developmentGO:00147062930.020
ribonucleotide metabolic processGO:00092592910.019
mitotic cell cycleGO:00002781950.019
nucleotide metabolic processGO:00091173320.019
carbohydrate metabolic processGO:00059752300.019
membrane organizationGO:00610242450.019
sulfur compound metabolic processGO:00067901000.019
positive regulation of protein modification processGO:00314012990.019
protein secretionGO:00093061110.019
cell fate commitmentGO:00451652100.019
protein modification by small protein conjugation or removalGO:00706472070.019
cell type specific apoptotic processGO:00972852680.018
regulation of cell projection organizationGO:00313442060.018
ubiquitin dependent protein catabolic processGO:00065111290.018
fat soluble vitamin biosynthetic processGO:004236240.018
cellular homeostasisGO:00197252400.018
purine nucleoside triphosphate metabolic processGO:00091442260.018
neural tube developmentGO:00219151600.018
regulation of t cell proliferationGO:0042129920.018
ribose phosphate metabolic processGO:00196932910.017
nucleoside catabolic processGO:00091642060.017
circulatory system processGO:00030131970.017
negative regulation of growthGO:0045926990.017
cellular response to dna damage stimulusGO:00069742070.017
regulation of cellular catabolic processGO:00313292420.017
forebrain developmentGO:00309003020.017
divalent inorganic cation transportGO:00725111780.017
defense response to gram positive bacteriumGO:0050830500.017
glycoprotein metabolic processGO:00091001160.017
proteolysis involved in cellular protein catabolic processGO:00516031470.017
protein modification by small protein conjugationGO:00324461870.016
carbohydrate derivative biosynthetic processGO:19011371830.016
response to inorganic substanceGO:0010035960.016
axonogenesisGO:00074092740.016
nucleoside phosphate metabolic processGO:00067533380.016
spinal cord developmentGO:0021510810.016
gamma delta t cell lineage commitmentGO:000236510.016
positive regulation of immune effector processGO:00026991070.016
aromatic compound catabolic processGO:00194392860.016
ribonucleoside catabolic processGO:00424542060.016
microtubule based processGO:00070172360.016
embryonic organ morphogenesisGO:00485622760.016
organic cyclic compound catabolic processGO:19013612950.016
regulation of cell morphogenesis involved in differentiationGO:00107691510.016
defense response to gram negative bacteriumGO:0050829280.016
metal ion homeostasisGO:00550651890.016
positive regulation of cell activationGO:00508671580.016
modification dependent protein catabolic processGO:00199411330.016
nucleoside triphosphate metabolic processGO:00091412300.016
nucleoside phosphate catabolic processGO:19012922220.015
production of molecular mediator of immune responseGO:00024401030.015
alcohol metabolic processGO:00060661160.015
negative regulation of cell activationGO:00508661110.015
protein oligomerizationGO:0051259670.015
nucleoside triphosphate catabolic processGO:00091432050.015
oxidation reduction processGO:00551143420.015
mitotic cell cycle processGO:19030471590.015
ribonucleoside metabolic processGO:00091192450.015
organophosphate catabolic processGO:00464342320.015
germ cell developmentGO:00072811850.015
ras protein signal transductionGO:0007265770.015
lipid catabolic processGO:0016042690.015
cellular response to cytokine stimulusGO:00713451890.015
glycoprotein biosynthetic processGO:0009101890.015
muscle cell differentiationGO:00426922610.015
regulation of proteolysisGO:00301621640.015
regulation of cell migrationGO:00303342190.015
myeloid leukocyte activationGO:0002274830.015
muscle cell developmentGO:00550011330.015
purine ribonucleotide metabolic processGO:00091502900.015
regulation of interleukin 8 secretionGO:200048220.015
purine ribonucleoside catabolic processGO:00461302050.015
blood circulationGO:00080151950.014
positive regulation of secretionGO:00510471300.014
regulation of feeding behaviorGO:006025930.014
b cell activationGO:00421131610.014
response to organonitrogen compoundGO:00102432460.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
sensory organ morphogenesisGO:00905962420.014
developmental maturationGO:00217001930.014
detection of bacterial lipoproteinGO:004249410.014
ribonucleotide catabolic processGO:00092612080.014
nucleoside metabolic processGO:00091162460.014
organic hydroxy compound metabolic processGO:19016152030.014
cellular protein catabolic processGO:00442571550.014
negative regulation of interleukin 8 secretionGO:200048310.014
carboxylic acid biosynthetic processGO:0046394860.014
ion transmembrane transportGO:00342203610.014
small gtpase mediated signal transductionGO:0007264970.014
regulation of neuron differentiationGO:00456642810.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
regulation of cell growthGO:0001558910.014
purine nucleoside metabolic processGO:00422782410.014
protein maturationGO:00516041760.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
immune response regulating signaling pathwayGO:00027641250.014
regulation of cell cycle processGO:00105641600.014
naphthalene metabolic processGO:001893110.013
negative regulation of cell proliferationGO:00082852960.013
myosin filament assemblyGO:003103420.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
wnt signaling pathwayGO:00160551880.013
exocytosisGO:00068871210.013
regulation of neuron projection developmentGO:00109751690.013
cytokine secretionGO:0050663720.013
cellular response to biotic stimulusGO:0071216920.013
nucleotide catabolic processGO:00091662170.013
posttranscriptional regulation of gene expressionGO:00106081550.013
purine ribonucleoside metabolic processGO:00461282410.013
adaptive immune responseGO:00022501550.013
regulation of lymphocyte differentiationGO:00456191070.013
immune response activating signal transductionGO:00027571160.013
cellular macromolecule catabolic processGO:00442652060.013
regulation of vesicle mediated transportGO:00606271390.013
oocyte constructionGO:000730820.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
muscle tissue developmentGO:00605373080.013
regulation of cell motilityGO:20001452360.013
lipid biosynthetic processGO:00086101790.012
regulation of protein transportGO:00512231630.012
regulation of leukocyte differentiationGO:19021051590.012
regulation of interleukin 10 secretionGO:200117940.012
atp catabolic processGO:0006200550.012
regulation of leukocyte proliferationGO:00706631210.012
respiratory system developmentGO:00605411900.012
cellular lipid metabolic processGO:00442553230.012
purine containing compound catabolic processGO:00725232130.012
modification dependent macromolecule catabolic processGO:00436321330.012
organonitrogen compound biosynthetic processGO:19015661920.012
leukocyte mediated immunityGO:00024431740.012
negative regulation of cellular component organizationGO:00511291940.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
regulation of protein secretionGO:0050708820.012
proteoglycan metabolic processGO:0006029380.012
negative regulation of protein metabolic processGO:00512482820.012
plasma membrane organizationGO:0007009900.012
nucleocytoplasmic transportGO:00069131390.012
regulation of cell sizeGO:0008361720.012
positive regulation of defense responseGO:00313491240.012
negative regulation of cell developmentGO:00107211690.012
regulation of lymphocyte proliferationGO:00506701170.012
regulation of blood pressureGO:0008217930.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
regulation of hormone levelsGO:00108172110.012
multi multicellular organism processGO:00447061090.012
nuclear divisionGO:00002801580.012
negative regulation of cytokine productionGO:0001818840.012
regulation of cytokine secretionGO:0050707610.012
regulation of leukocyte mediated immunityGO:00027031040.012
cartilage developmentGO:00512161400.012
glycosyl compound metabolic processGO:19016572460.012
regulation of hydrolase activityGO:00513362460.011
antimicrobial peptide biosynthetic processGO:000277720.011
macromolecule catabolic processGO:00090572810.011
monocarboxylic acid metabolic processGO:00327871910.011
chromatin organizationGO:00063252060.011
interleukin 10 secretionGO:007260840.011
humoral immune responseGO:0006959570.011
regulation of protein maturationGO:1903317960.011
nucleoside monophosphate metabolic processGO:0009123850.011
ribonucleoside monophosphate catabolic processGO:0009158570.011
innate immune responseGO:00450871570.011
regulation of protein complex assemblyGO:0043254830.011
negative regulation of secretion by cellGO:1903531540.011
response to painGO:0048265260.011
activation of immune responseGO:00022531380.011
purine ribonucleotide catabolic processGO:00091542080.011
calcium ion transportGO:00068161590.011
regulation of anatomical structure sizeGO:00900661780.011
stem cell differentiationGO:00488632680.011
carbohydrate derivative catabolic processGO:19011362310.011
compound eye developmentGO:004874910.011
cell fate specificationGO:0001708720.011
regulation of innate immune responseGO:0045088910.011
multicellular organismal homeostasisGO:00488711640.011
cellular response to molecule of bacterial originGO:0071219830.011
regulation of cytoskeleton organizationGO:00514931220.011
negative regulation of cellular amine metabolic processGO:003323910.011
chemokine productionGO:0032602340.011
lipid transportGO:0006869980.011
somatotropin secreting cell differentiationGO:006012640.011
cellular response to lipopolysaccharideGO:0071222770.011
naphthalene containing compound metabolic processGO:009042010.011
lymphocyte activation involved in immune responseGO:0002285930.011
g1 s transition of mitotic cell cycleGO:0000082570.011
regionalizationGO:00030023370.011
steroid metabolic processGO:00082021190.011
neuron projection extensionGO:1990138640.011
microtubule cytoskeleton organizationGO:00002261570.011
peptidyl amino acid modificationGO:00181933360.011
negative regulation of secretionGO:0051048610.011
antimicrobial peptide productionGO:000277520.011
skeletal muscle organ developmentGO:00605381630.011
meiotic cell cycleGO:00513211220.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.010
regulation of metal ion transportGO:00109591060.010
atp metabolic processGO:0046034750.010
receptor mediated endocytosisGO:0006898510.010
regulation of striated muscle cell differentiationGO:0051153810.010
negative regulation of cellular response to growth factor stimulusGO:0090288460.010
cellular response to hormone stimulusGO:00328701500.010
regulation of protein processingGO:0070613960.010
organic hydroxy compound biosynthetic processGO:1901617770.010
lymphocyte mediated immunityGO:00024491390.010
positive regulation of cellular catabolic processGO:00313311480.010
regulation of system processGO:00440572000.010
response to acid chemicalGO:00011011110.010
protein localization to membraneGO:00726571080.010
negative regulation of lymphocyte activationGO:0051250910.010
intracellular protein transportGO:00068862040.010
mesodermal cell migrationGO:000807840.010
rho protein signal transductionGO:0007266320.010
positive regulation of lymphocyte activationGO:00512511400.010
organelle fissionGO:00482851700.010
regulation of cellular component biogenesisGO:00440871810.010

Astl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
inherited metabolic disorderDOID:65500.012
disease of cellular proliferationDOID:1456600.010
gastrointestinal system cancerDOID:311900.010
cancerDOID:16200.010
organ system cancerDOID:005068600.010