Mus musculus

226 known processes

Gpx1

glutathione peroxidase 1

(Aliases: AI195024,GPx-1,AL033363,CGPx,Gpx,GSHPx-1)

Gpx1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular hyperosmotic salinity responseGO:007147501.000
cellular response to salt stressGO:007147210.535
response to hydroperoxideGO:003319460.308
oxidation reduction processGO:00551143420.295
cellular lipid metabolic processGO:00442553230.267
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.227
response to acid chemicalGO:00011011110.223
cellular hyperosmotic responseGO:007147400.220
response to organonitrogen compoundGO:00102432460.213
cellular response to lipidGO:00713961450.201
cellular amino acid metabolic processGO:00065201030.185
reactive oxygen species metabolic processGO:0072593840.178
cellular modified amino acid metabolic processGO:0006575630.132
cellular response to acid chemicalGO:0071229680.128
regulation of cellular ketone metabolic processGO:0010565660.121
response to organic cyclic compoundGO:00140701980.117
positive regulation of cell deathGO:00109422240.110
protein oxidationGO:001815820.109
cellular response to amino acid stimulusGO:0071230290.100
hydrogen peroxide catabolic processGO:004274450.089
response to steroid hormoneGO:0048545560.083
negative regulation of apoptotic signaling pathwayGO:20012341040.083
response to symbiontGO:000960820.081
cellular ketone metabolic processGO:0042180840.078
negative regulation of response to oxidative stressGO:1902883100.078
regulation of cellular amino acid metabolic processGO:000652150.071
response to molecule of fungal originGO:000223840.069
regulation of cellular response to stressGO:00801351590.069
regulation of apoptotic signaling pathwayGO:20012331970.067
inflammatory responseGO:00069542440.063
amine metabolic processGO:0009308450.063
ameboidal type cell migrationGO:00016671280.062
symbiosis encompassing mutualism through parasitismGO:0044403830.061
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.060
cell type specific apoptotic processGO:00972852680.058
cellular response to osmotic stressGO:007147070.057
organic cyclic compound catabolic processGO:19013612950.057
positive regulation of cellular amino acid metabolic processGO:004576430.057
cellular macromolecule catabolic processGO:00442652060.056
cellular response to oxidative stressGO:0034599760.054
neutral lipid metabolic processGO:0006638570.054
tissue migrationGO:0090130680.054
purine containing compound metabolic processGO:00725213110.053
regulation of cellular amine metabolic processGO:0033238200.052
myotube cell developmentGO:0014904600.052
striated muscle tissue developmentGO:00147062930.052
muscle cell developmentGO:00550011330.051
interaction with symbiontGO:0051702140.050
epithelial cell migrationGO:0010631630.049
cellular amine metabolic processGO:0044106440.049
inflammatory response to antigenic stimulusGO:0002437300.049
positive regulation of protein phosphorylationGO:00019342420.048
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.048
cellular chemical homeostasisGO:00550822150.047
glutathione metabolic processGO:0006749160.047
regulation of cellular response to oxidative stressGO:1900407190.047
multicellular organismal homeostasisGO:00488711640.046
cellular response to estrogen stimulusGO:0071391120.045
positive regulation of protein modification processGO:00314012990.045
skeletal muscle organ developmentGO:00605381630.045
hyperosmotic responseGO:000697240.045
circulatory system processGO:00030131970.045
regulation of response to oxidative stressGO:1902882190.045
blood vessel endothelial cell migrationGO:0043534230.044
neuron deathGO:00709971540.044
response to oxidative stressGO:00069791230.044
cellular homeostasisGO:00197252400.044
pigment metabolic processGO:0042440320.043
immune effector processGO:00022523210.043
sensory perception of soundGO:0007605970.043
positive regulation of programmed cell deathGO:00430682180.042
blood vessel morphogenesisGO:00485142850.042
response to reactive oxygen speciesGO:0000302560.041
regulation of proteolysisGO:00301621640.041
vasodilationGO:0042311280.041
positive regulation of apoptotic processGO:00430652170.040
pigment biosynthetic processGO:0046148260.040
acylglycerol metabolic processGO:0006639550.039
apoptotic signaling pathwayGO:00971903060.039
interspecies interaction between organismsGO:0044419830.039
response to molecule of bacterial originGO:00022371430.038
regulation of hydrolase activityGO:00513362460.037
response to ionizing radiationGO:0010212420.037
skeletal muscle fiber developmentGO:0048741580.036
sterol metabolic processGO:0016125580.036
skeletal muscle tissue regenerationGO:0043403200.035
heterocycle catabolic processGO:00467002800.035
regulation of response to woundingGO:19030341890.035
negative regulation of oxidative stress induced cell deathGO:190320290.034
gland developmentGO:00487323300.034
response to osmotic stressGO:0006970210.034
muscle tissue developmentGO:00605373080.033
positive regulation of mapk cascadeGO:00434101700.033
regulation of protein kinase activityGO:00458592320.033
muscle fiber developmentGO:0048747760.032
muscle cell differentiationGO:00426922610.032
negative regulation of immune system processGO:00026832090.032
positive regulation of transferase activityGO:00513471670.032
wound healingGO:00420601570.031
innate immune responseGO:00450871570.031
negative regulation of cellular response to oxidative stressGO:1900408100.031
angiogenesisGO:00015252010.031
regulation of secretionGO:00510462740.031
epithelial cell developmentGO:00020641590.031
regulation of mapk cascadeGO:00434082480.031
cellular response to steroid hormone stimulusGO:0071383330.031
positive regulation of cellular amine metabolic processGO:003324050.030
epithelium migrationGO:0090132630.030
purine nucleoside metabolic processGO:00422782410.029
nitrogen compound transportGO:00717052710.029
mapk cascadeGO:00001652810.029
negative regulation of defense responseGO:0031348770.029
protein modification by small protein conjugation or removalGO:00706472070.029
metal ion homeostasisGO:00550651890.028
negative regulation of molecular functionGO:00440922580.028
myoblast proliferationGO:0051450110.028
positive regulation of kinase activityGO:00336741550.028
cation transportGO:00068123990.028
carbohydrate homeostasisGO:00335001280.028
protein processingGO:00164851630.028
regulation of kinase activityGO:00435492490.028
regulation of transmembrane transportGO:00347621280.028
regulation of ion transportGO:00432692150.028
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.027
triglyceride metabolic processGO:0006641510.027
endothelial cell developmentGO:0001885200.027
negative regulation of cellular protein metabolic processGO:00322692470.027
regulation of homeostatic processGO:00328441820.026
response to radiationGO:00093141650.026
regulation of cell adhesionGO:00301551540.026
ion transmembrane transportGO:00342203610.026
striated muscle cell developmentGO:00550021250.025
sulfur compound metabolic processGO:00067901000.024
single organism cell adhesionGO:00986021560.024
nucleotide metabolic processGO:00091173320.024
intrinsic apoptotic signaling pathwayGO:00971931320.024
negative regulation of inflammatory responseGO:0050728610.024
male gamete generationGO:00482322850.024
protein kinase b signalingGO:0043491740.024
protein maturationGO:00516041760.024
regulation of transferase activityGO:00513382630.024
cation homeostasisGO:00550802120.024
nucleoside phosphate biosynthetic processGO:1901293790.024
negative regulation of protein metabolic processGO:00512482820.024
protein catabolic processGO:00301632210.024
regulation of tube sizeGO:0035150570.023
macromolecule catabolic processGO:00090572810.023
positive regulation of reactive oxygen species metabolic processGO:2000379110.023
response to inorganic substanceGO:0010035960.023
defense response to other organismGO:00985421970.022
regulation of cellular catabolic processGO:00313292420.022
epithelial cell proliferationGO:00506731740.022
fatty acid metabolic processGO:00066311210.022
cellular response to hormone stimulusGO:00328701500.022
monocarboxylic acid metabolic processGO:00327871910.022
regulation of protein localizationGO:00328802310.022
regulation of endocytosisGO:0030100690.022
glucose homeostasisGO:00425931280.022
response to mineralocorticoidGO:005138510.022
peptidyl amino acid modificationGO:00181933360.022
nucleobase containing small molecule metabolic processGO:00550863520.022
endothelial cell differentiationGO:0045446410.021
negative regulation of cellular component organizationGO:00511291940.021
myeloid cell differentiationGO:00300992330.021
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transportGO:009011810.021
regulation of cell motilityGO:20001452360.021
nucleoside phosphate metabolic processGO:00067533380.021
positive regulation of protein kinase activityGO:00458601440.021
regulation of bindingGO:00510981110.021
regulation of protein processingGO:0070613960.021
aromatic compound catabolic processGO:00194392860.021
cellular metal ion homeostasisGO:00068751510.020
cellular nitrogen compound catabolic processGO:00442702800.020
organic acid biosynthetic processGO:0016053860.020
anatomical structure homeostasisGO:00602491450.020
ribonucleoside metabolic processGO:00091192450.020
peptidyl tyrosine phosphorylationGO:00181081430.020
sensory perception of mechanical stimulusGO:00509541070.020
cofactor metabolic processGO:0051186800.020
response to amino acidGO:0043200370.020
detection of molecule of bacterial originGO:003249020.020
myeloid cell homeostasisGO:00022621140.019
blood circulationGO:00080151950.019
transmembrane transportGO:00550854120.019
regulation of body fluid levelsGO:00508781620.019
regulation of cell migrationGO:00303342190.019
second messenger mediated signalingGO:0019932730.019
multi multicellular organism processGO:00447061090.019
response to symbiotic bacteriumGO:000960920.019
innate immune response in mucosaGO:000222730.018
regulation of phospholipase a2 activityGO:003242930.018
regulation of hormone levelsGO:00108172110.018
lateral inhibitionGO:004633110.018
negative regulation of cell proliferationGO:00082852960.018
regulation of peptidase activityGO:0052547960.018
regulation of cell morphogenesis involved in differentiationGO:00107691510.018
regulation of defense responseGO:00313472330.018
lipid biosynthetic processGO:00086101790.018
steroid metabolic processGO:00082021190.018
negative regulation of proteolysisGO:0045861740.018
negative regulation of sterol transportGO:003237240.018
cell killingGO:0001906670.018
alcohol metabolic processGO:00060661160.017
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217590.017
regulation of presynaptic membrane organizationGO:190162930.017
cellular response to molecule of bacterial originGO:0071219830.017
cellular response to biotic stimulusGO:0071216920.017
regulation of cytokine productionGO:00018172660.017
heart contractionGO:0060047930.017
protein localization to membraneGO:00726571080.017
response to monosaccharideGO:0034284670.017
cellular response to dna damage stimulusGO:00069742070.017
leukocyte mediated immunityGO:00024431740.017
positive regulation of bindingGO:0051099490.017
regulation of cell projection organizationGO:00313442060.017
negative regulation of neuron differentiationGO:00456651010.017
negative regulation of cholesterol transportGO:003237540.017
regulation of reactive oxygen species metabolic processGO:2000377400.017
cellular response to cytokine stimulusGO:00713451890.016
membrane organizationGO:00610242450.016
modification dependent protein catabolic processGO:00199411330.016
response to endoplasmic reticulum stressGO:0034976530.016
fat cell differentiationGO:00454441600.016
spermatogenesisGO:00072832840.016
regulation of cell activationGO:00508652890.016
coenzyme metabolic processGO:0006732520.016
monosaccharide metabolic processGO:00059961060.016
response to xenobiotic stimulusGO:0009410130.016
leukocyte proliferationGO:00706611720.016
positive regulation of phagocytosisGO:0050766260.016
regulation of secretion by cellGO:19035302490.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
porphyrin containing compound metabolic processGO:0006778220.016
peptide metabolic processGO:0006518460.016
posttranscriptional regulation of gene expressionGO:00106081550.016
carboxylic acid biosynthetic processGO:0046394860.016
myotube differentiationGO:00149021050.016
adaptive immune responseGO:00022501550.016
regulation of anatomical structure sizeGO:00900661780.016
nucleosome disassemblyGO:000633710.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
hexose metabolic processGO:0019318980.015
hematopoietic progenitor cell differentiationGO:00022441430.015
cellular response to lipopolysaccharideGO:0071222770.015
organonitrogen compound catabolic processGO:19015652640.015
purine nucleobase biosynthetic processGO:000911330.015
ribose phosphate metabolic processGO:00196932910.015
cytokine productionGO:00018163190.015
cholesterol metabolic processGO:0008203560.015
cofactor catabolic processGO:005118760.015
ras protein signal transductionGO:0007265770.015
cellular protein complex assemblyGO:00436231160.015
morphogenesis of a branching structureGO:00017632030.015
regulation of protein kinase b signalingGO:0051896560.015
signal transduction in absence of ligandGO:0038034550.015
response to hydrogen peroxideGO:0042542320.015
regulation of epithelial cell proliferationGO:00506781410.015
negative regulation of intracellular signal transductionGO:19025321670.015
regulation of intracellular transportGO:00323861590.015
hydrogen peroxide metabolic processGO:0042743160.015
ossificationGO:00015032160.015
intracellular protein transportGO:00068862040.014
regulation of ion transmembrane transportGO:00347651190.014
regulation of transporter activityGO:0032409570.014
homeostasis of number of cellsGO:00488722100.014
regulation of engulfment of apoptotic cellGO:190107420.014
regulation of protein transportGO:00512231630.014
protein localization to organelleGO:00333651850.014
leukocyte migrationGO:00509001240.014
response to lipopolysaccharideGO:00324961280.014
cytoplasmic transportGO:00164822340.014
regulation of inflammatory responseGO:00507271470.014
amide transportGO:00428861380.014
regulation of organelle organizationGO:00330432890.014
regulation of ion transmembrane transporter activityGO:0032412540.014
defense response to bacteriumGO:00427421190.014
small molecule biosynthetic processGO:00442831320.014
regulation of multi organism processGO:00439001110.014
extrinsic apoptotic signaling pathwayGO:00971911260.014
cellular glucose homeostasisGO:0001678520.014
response to oxygen radicalGO:0000305160.014
regulation of reactive oxygen species biosynthetic processGO:190342620.014
response to iron ionGO:001003940.014
lymphocyte mediated immunityGO:00024491390.014
morphogenesis of a branching epitheliumGO:00611381930.013
t cell differentiationGO:00302171740.013
tumor necrosis factor productionGO:0032640500.013
purine containing compound biosynthetic processGO:0072522700.013
humoral immune responseGO:0006959570.013
endothelium developmentGO:0003158450.013
synaptic transmissionGO:00072683290.013
alpha amino acid metabolic processGO:1901605590.013
cellular protein catabolic processGO:00442571550.013
dna repairGO:00062811070.013
nucleoside metabolic processGO:00091162460.013
leukocyte differentiationGO:00025213420.013
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.013
regulation of protein serine threonine kinase activityGO:00719001570.013
purine ribonucleoside biosynthetic processGO:0046129190.013
peptidyl tyrosine modificationGO:00182121450.013
purine nucleotide metabolic processGO:00061633020.013
regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014810.013
regulation of leukocyte mediated immunityGO:00027031040.013
camera type eye developmentGO:00430102660.013
regulation of protein catabolic processGO:00421761080.013
sensory perceptionGO:00076002450.013
cellular calcium ion homeostasisGO:00068741190.013
kidney developmentGO:00018222130.013
pyridine containing compound catabolic processGO:007252640.013
regulation of inflammatory response to antigenic stimulusGO:0002861210.013
regulation of peptidyl tyrosine phosphorylationGO:0050730930.013
lymphocyte proliferationGO:00466511640.012
calcium ion homeostasisGO:00550741270.012
lymphocyte differentiationGO:00300982420.012
hormone metabolic processGO:0042445860.012
regulation of cellular component biogenesisGO:00440871810.012
regulation of endopeptidase activityGO:0052548890.012
regulation of ossificationGO:00302781120.012
insulin secretion involved in cellular response to glucose stimulusGO:0035773360.012
organonitrogen compound biosynthetic processGO:19015661920.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.012
cellular response to hexose stimulusGO:0071331470.012
epidermis developmentGO:00085441870.012
glycosyl compound metabolic processGO:19016572460.012
response to testosteroneGO:003357430.012
urogenital system developmentGO:00016552610.012
actin cytoskeleton organizationGO:00300362200.012
regulation of neuron projection developmentGO:00109751690.012
carbohydrate derivative biosynthetic processGO:19011371830.012
germ cell developmentGO:00072811850.012
translationGO:0006412930.012
carbohydrate metabolic processGO:00059752300.012
negative regulation of protein maturationGO:1903318790.012
positive regulation of cell activationGO:00508671580.012
monocarboxylic acid biosynthetic processGO:0072330610.012
cognitionGO:00508901490.012
regulation of membrane potentialGO:00423911920.012
regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016310.012
gonad developmentGO:00084061410.012
regulation of establishment of protein localizationGO:00702011810.012
response to drugGO:0042493750.012
endocytosisGO:00068971680.012
negative regulation of homeostatic processGO:0032845710.012
regulation of myeloid cell differentiationGO:0045637960.012
organophosphate biosynthetic processGO:00904071220.011
cellular amide metabolic processGO:0043603580.011
cellular response to growth factor stimulusGO:00713631970.011
purine nucleobase metabolic processGO:000614440.011
defense response to gram positive bacteriumGO:0050830500.011
purine ribonucleoside metabolic processGO:00461282410.011
regulation of intracellular protein transportGO:0033157820.011
leukocyte mediated cytotoxicityGO:0001909620.011
phagocytosisGO:0006909660.011
carboxylic acid catabolic processGO:0046395510.011
tissue remodelingGO:00487711020.011
negative regulation of peptidase activityGO:0010466460.011
adiponectin activated signaling pathwayGO:003321140.011
protein ubiquitinationGO:00165671710.011
angiogenesis involved in wound healingGO:006005570.011
regulation of fat cell differentiationGO:0045598810.011
nucleocytoplasmic transportGO:00069131390.011
response to superoxideGO:0000303160.011
spermatid differentiationGO:00485151150.011
transition metal ion homeostasisGO:0055076540.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
positive regulation of cell motilityGO:20001471160.011
positive regulation of proteolysisGO:0045862850.011
establishment of protein localization to organelleGO:00725941180.011
myeloid leukocyte differentiationGO:00025731190.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
multicellular organismal signalingGO:0035637910.010
cellular response to monosaccharide stimulusGO:0071326470.010
regulation of plasma lipoprotein particle levelsGO:0097006230.010
developmental growth involved in morphogenesisGO:00605601380.010
actin filament organizationGO:00070151130.010
purine nucleoside biosynthetic processGO:0042451190.010
nuclear importGO:0051170950.010
glial cell differentiationGO:00100011310.010
placenta developmentGO:00018901400.010
cellular response to arsenic containing substanceGO:007124340.010
chromatin disassemblyGO:003149810.010
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016210.010
calcium mediated signalingGO:0019722460.010
regulation of lymphocyte mediated immunityGO:0002706840.010
regulation of glutamate receptor signaling pathwayGO:1900449160.010
ubiquitin dependent protein catabolic processGO:00065111290.010
skin developmentGO:00435882200.010
regulation of vesicle mediated transportGO:00606271390.010

Gpx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.038
immune system diseaseDOID:291400.032
disease of metabolismDOID:001466700.030
inherited metabolic disorderDOID:65500.030
musculoskeletal system diseaseDOID:1700.023
connective tissue diseaseDOID:6500.023
primary immunodeficiency diseaseDOID:61200.013
central nervous system diseaseDOID:33100.013
sensory system diseaseDOID:005015500.012