IMP: Integrative Multi-species Prediction

Mus musculus

29 known processes

Gpx3

glutathione peroxidase 3

(Aliases: AA960521,EGPx,GPx,GSHPx-P,GSHPx-3)

Ensembl: ENSMUSG00000018339
Entrez: 14778
UniProtKB: P46412

Process Predictions
Disease Predictions

Gpx3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
oxidation reduction process	GO:0055114	342	0.299
regulation of cellular ketone metabolic process	GO:0010565	66	0.262
peptidyl amino acid modification	GO:0018193	336	0.226
circulatory system process	GO:0003013	197	0.222	Mouse
cell adhesion	GO:0007155	329	0.221
regulation of hydrolase activity	GO:0051336	246	0.207
blood vessel morphogenesis	GO:0048514	285	0.190	Mouse
regulation of hormone levels	GO:0010817	211	0.175
regulation of cellular amino acid metabolic process	GO:0006521	5	0.171
inflammatory response	GO:0006954	244	0.170	Mouse
amine metabolic process	GO:0009308	45	0.168
positive regulation of mapk cascade	GO:0043410	170	0.168
muscle cell differentiation	GO:0042692	261	0.164	Mouse
carbohydrate metabolic process	GO:0005975	230	0.164
urogenital system development	GO:0001655	261	0.155
fat cell differentiation	GO:0045444	160	0.150	Mouse
regulation of cell motility	GO:2000145	236	0.141
regulation of cellular amine metabolic process	GO:0033238	20	0.137
carbohydrate homeostasis	GO:0033500	128	0.135
cellular ketone metabolic process	GO:0042180	84	0.135
regulation of cell migration	GO:0030334	219	0.131
negative regulation of protein metabolic process	GO:0051248	282	0.129
skeletal muscle organ development	GO:0060538	163	0.127	Mouse
extracellular matrix organization	GO:0030198	147	0.126
muscle tissue development	GO:0060537	308	0.125	Mouse
cellular amine metabolic process	GO:0044106	44	0.124
cellular lipid metabolic process	GO:0044255	323	0.124	Mouse
regulation of glucose metabolic process	GO:0010906	60	0.118
protein kinase b signaling	GO:0043491	74	0.113	Mouse
glucose homeostasis	GO:0042593	128	0.109
wound healing	GO:0042060	157	0.106	Mouse
cell type specific apoptotic process	GO:0097285	268	0.106	Mouse
negative regulation of cellular protein metabolic process	GO:0032269	247	0.104
cellular response to hormone stimulus	GO:0032870	150	0.102
muscle cell development	GO:0055001	133	0.100	Mouse
negative regulation of molecular function	GO:0044092	258	0.098
positive regulation of protein modification process	GO:0031401	299	0.097
regulation of peptidase activity	GO:0052547	96	0.097
positive regulation of protein phosphorylation	GO:0001934	242	0.096
response to organonitrogen compound	GO:0010243	246	0.094
cellular amino acid metabolic process	GO:0006520	103	0.092	Rat
regulation of protein localization	GO:0032880	231	0.091
protein localization to organelle	GO:0033365	185	0.091
regulation of transferase activity	GO:0051338	263	0.089
response to peptide	GO:1901652	136	0.088
response to monosaccharide	GO:0034284	67	0.082
epithelial cell development	GO:0002064	159	0.082	Mouse
regulation of actin filament based process	GO:0032970	99	0.081
apoptotic signaling pathway	GO:0097190	306	0.079	Mouse
regulation of proteolysis	GO:0030162	164	0.078
negative regulation of proteolysis	GO:0045861	74	0.077
regulation of apoptotic signaling pathway	GO:2001233	197	0.077	Mouse
small gtpase mediated signal transduction	GO:0007264	97	0.076
triglyceride metabolic process	GO:0006641	51	0.076	Mouse
negative regulation of hydrolase activity	GO:0051346	71	0.076
regulation of protein kinase activity	GO:0045859	232	0.075
cellular response to growth factor stimulus	GO:0071363	197	0.074
organonitrogen compound catabolic process	GO:1901565	264	0.072
ossification	GO:0001503	216	0.072
regulation of blood pressure	GO:0008217	93	0.072
vascular process in circulatory system	GO:0003018	62	0.070	Mouse
actin cytoskeleton organization	GO:0030036	220	0.070
negative regulation of intracellular signal transduction	GO:1902532	167	0.069	Mouse
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.069	Mouse
regulation of vasculature development	GO:1901342	88	0.069
positive regulation of cellular amine metabolic process	GO:0033240	5	0.068
blood circulation	GO:0008015	195	0.068	Mouse
response to radiation	GO:0009314	165	0.068	Mouse
kidney development	GO:0001822	213	0.067
regulation of angiogenesis	GO:0045765	81	0.066
ameboidal type cell migration	GO:0001667	128	0.065	Mouse
striated muscle tissue development	GO:0014706	293	0.064	Mouse
protein maturation	GO:0051604	176	0.064
response to nutrient levels	GO:0031667	109	0.064
neutral lipid metabolic process	GO:0006638	57	0.064	Mouse
monosaccharide metabolic process	GO:0005996	106	0.063
response to extracellular stimulus	GO:0009991	127	0.063
mapk cascade	GO:0000165	281	0.062
hormone secretion	GO:0046879	128	0.061
response to peptide hormone	GO:0043434	127	0.061
glycerolipid metabolic process	GO:0046486	122	0.060	Mouse
response to insulin	GO:0032868	100	0.060
intracellular protein transport	GO:0006886	204	0.060
embryonic organ morphogenesis	GO:0048562	276	0.060
response to amino acid	GO:0043200	37	0.059
morphogenesis of a branching epithelium	GO:0061138	193	0.059
regulation of protein processing	GO:0070613	96	0.059
response to organic cyclic compound	GO:0014070	198	0.058	Rat
cell matrix adhesion	GO:0007160	68	0.058
endothelial cell differentiation	GO:0045446	41	0.058	Mouse
macromolecule catabolic process	GO:0009057	281	0.057
negative regulation of immune system process	GO:0002683	209	0.057	Mouse
regulation of kinase activity	GO:0043549	249	0.056
heart contraction	GO:0060047	93	0.056	Mouse
extracellular structure organization	GO:0043062	148	0.056
positive regulation of protein kinase activity	GO:0045860	144	0.055
g protein coupled receptor signaling pathway	GO:0007186	243	0.054
angiogenesis	GO:0001525	201	0.054	Mouse
regulation of anatomical structure size	GO:0090066	178	0.054	Mouse
gland development	GO:0048732	330	0.054
negative regulation of protein processing	GO:0010955	79	0.053
hexose metabolic process	GO:0019318	98	0.053
renal system development	GO:0072001	225	0.053
regulation of defense response	GO:0031347	233	0.052	Mouse
regulation of mapk cascade	GO:0043408	248	0.052
regulation of phospholipase a2 activity	GO:0032429	3	0.051
positive regulation of angiogenesis	GO:0045766	46	0.051
epithelial cell proliferation	GO:0050673	174	0.051
regulation of lipid metabolic process	GO:0019216	118	0.050
nucleoside phosphate metabolic process	GO:0006753	338	0.050
negative regulation of cell migration	GO:0030336	59	0.049
peptidyl tyrosine phosphorylation	GO:0018108	143	0.048
peptidyl tyrosine modification	GO:0018212	145	0.048
cellular carbohydrate metabolic process	GO:0044262	119	0.048
regulation of neuron death	GO:1901214	134	0.047	Mouse
positive regulation of nervous system development	GO:0051962	221	0.047
regulation of protein kinase b signaling	GO:0051896	56	0.047	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.047
neuronal action potential	GO:0019228	54	0.047
lipid biosynthetic process	GO:0008610	179	0.046
multicellular organism growth	GO:0035264	161	0.046
cellular chemical homeostasis	GO:0055082	215	0.046
muscle contraction	GO:0006936	101	0.046
protein targeting	GO:0006605	143	0.046
monocarboxylic acid metabolic process	GO:0032787	191	0.046
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.045
reactive oxygen species metabolic process	GO:0072593	84	0.045
positive regulation of apoptotic process	GO:0043065	217	0.045
cellular response to oxidative stress	GO:0034599	76	0.045
regulation of system process	GO:0044057	200	0.045
nitrogen compound transport	GO:0071705	271	0.044
negative regulation of peptidase activity	GO:0010466	46	0.044
regulation of fat cell differentiation	GO:0045598	81	0.043
positive regulation of transferase activity	GO:0051347	167	0.043
protein processing	GO:0016485	163	0.042
regulation of systemic arterial blood pressure	GO:0003073	61	0.042
regulation of secretion	GO:0051046	274	0.042
negative regulation of cell proliferation	GO:0008285	296	0.042
cellular homeostasis	GO:0019725	240	0.042
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	GO:2000166	1	0.041
cellular response to organonitrogen compound	GO:0071417	145	0.040
cell junction assembly	GO:0034329	52	0.040
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.040	Mouse
regulation of tube size	GO:0035150	57	0.039	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.039
cytoplasmic transport	GO:0016482	234	0.039
protein catabolic process	GO:0030163	221	0.038
protein localization to nucleus	GO:0034504	121	0.038
regulation of establishment of protein localization	GO:0070201	181	0.038
single organismal cell cell adhesion	GO:0016337	131	0.037
response to inorganic substance	GO:0010035	96	0.037
negative regulation of endopeptidase activity	GO:0010951	44	0.037
skeletal muscle fiber development	GO:0048741	58	0.037	Mouse
alcohol metabolic process	GO:0006066	116	0.037
formation of radial glial scaffolds	GO:0021943	4	0.037
ion transmembrane transport	GO:0034220	361	0.037
multicellular organismal homeostasis	GO:0048871	164	0.037	Mouse
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.036
cardiocyte differentiation	GO:0035051	87	0.036
lipid transport	GO:0006869	98	0.036
regulation of cellular response to stress	GO:0080135	159	0.036	Mouse
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.036
regulation of membrane potential	GO:0042391	192	0.036
cation homeostasis	GO:0055080	212	0.036
regulation of protein maturation	GO:1903317	96	0.036
wnt signaling pathway	GO:0016055	188	0.035
cellular response to peptide hormone stimulus	GO:0071375	92	0.035
epithelium migration	GO:0090132	63	0.035	Mouse
sphingolipid metabolic process	GO:0006665	45	0.035
regulation of ossification	GO:0030278	112	0.035
regulation of epithelial cell proliferation	GO:0050678	141	0.035
digestive system development	GO:0055123	200	0.034
intracellular sterol transport	GO:0032366	3	0.034
intrinsic apoptotic signaling pathway	GO:0097193	132	0.034	Mouse
neuron death	GO:0070997	154	0.034	Mouse
positive regulation of cell migration	GO:0030335	109	0.034
cellular response to peptide	GO:1901653	92	0.033
negative regulation of protein maturation	GO:1903318	79	0.033
epithelial tube morphogenesis	GO:0060562	303	0.033
skin development	GO:0043588	220	0.033
regulation of hormone secretion	GO:0046883	88	0.033
peptide secretion	GO:0002790	114	0.032
purine containing compound metabolic process	GO:0072521	311	0.032
nucleotide metabolic process	GO:0009117	332	0.032
regulation of organelle organization	GO:0033043	289	0.032
regulation of planar cell polarity pathway involved in outflow tract morphogenesis	GO:2000163	1	0.032
positive regulation of kinase activity	GO:0033674	155	0.031
positive regulation of cell death	GO:0010942	224	0.031
response to symbiont	GO:0009608	2	0.031	Mouse
peptide hormone secretion	GO:0030072	109	0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.031
nucleobase containing small molecule metabolic process	GO:0055086	352	0.031
peptide transport	GO:0015833	133	0.031
respiratory tube development	GO:0030323	167	0.031
amide transport	GO:0042886	138	0.031
spermatogenesis	GO:0007283	284	0.030
cellular response to monosaccharide stimulus	GO:0071326	47	0.030
negative regulation of protein phosphorylation	GO:0001933	126	0.030
response to acid chemical	GO:0001101	111	0.030
regulation of response to wounding	GO:1903034	189	0.030	Mouse
organic cyclic compound catabolic process	GO:1901361	295	0.030
response to oxidative stress	GO:0006979	123	0.030
regulation of response to oxidative stress	GO:1902882	19	0.029	Mouse
interspecies interaction between organisms	GO:0044419	83	0.029	Mouse
cell substrate adhesion	GO:0031589	130	0.029
negative regulation of phosphorylation	GO:0042326	166	0.029
regulation of homeostatic process	GO:0032844	182	0.029
single organism cell adhesion	GO:0098602	156	0.029
cell migration involved in kidney development	GO:0035787	3	0.029
purine nucleoside metabolic process	GO:0042278	241	0.029
epidermis development	GO:0008544	187	0.029
aromatic compound catabolic process	GO:0019439	286	0.029
negative regulation of cell motility	GO:2000146	61	0.029
mesonephros development	GO:0001823	97	0.029
leukocyte differentiation	GO:0002521	342	0.029
nuclear import	GO:0051170	95	0.029
lung development	GO:0030324	164	0.029
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:2000162	1	0.029
stem cell differentiation	GO:0048863	268	0.028
gliogenesis	GO:0042063	141	0.028
locomotory behavior	GO:0007626	195	0.028
regulation of peptide secretion	GO:0002791	77	0.028
negative regulation of platelet derived growth factor receptor beta signaling pathway	GO:2000587	2	0.028
cellular response to extracellular stimulus	GO:0031668	81	0.028
protein import	GO:0017038	101	0.028
regulation of protein catabolic process	GO:0042176	108	0.028
negative regulation of phosphorus metabolic process	GO:0010563	184	0.027
membrane organization	GO:0061024	245	0.027
myotube differentiation	GO:0014902	105	0.027	Mouse
establishment of protein localization to organelle	GO:0072594	118	0.027
organic hydroxy compound transport	GO:0015850	93	0.027
metanephric mesenchymal cell migration	GO:0035789	2	0.027
renal system process	GO:0003014	48	0.027
regulation of endopeptidase activity	GO:0052548	89	0.027
heterocycle catabolic process	GO:0046700	280	0.027
regulation of secretion by cell	GO:1903530	249	0.026
negative regulation of nervous system development	GO:0051961	156	0.026
striated muscle cell development	GO:0055002	125	0.026	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	157	0.026
anatomical structure homeostasis	GO:0060249	145	0.026
negative regulation of ossification	GO:0030279	49	0.026
insulin secretion	GO:0030073	89	0.026
male gonad development	GO:0008584	88	0.026
cellular glucose homeostasis	GO:0001678	52	0.026
regulation of inflammatory response	GO:0050727	147	0.026	Mouse
nuclear transport	GO:0051169	139	0.026
purine ribonucleotide catabolic process	GO:0009154	208	0.025
epithelial cell migration	GO:0010631	63	0.025	Mouse
steroid metabolic process	GO:0008202	119	0.025
negative regulation of leukocyte differentiation	GO:1902106	51	0.025
positive regulation of cellular component biogenesis	GO:0044089	94	0.025
positive regulation of protein kinase b signaling	GO:0051897	32	0.025	Mouse
platelet derived growth factor receptor beta signaling pathway	GO:0035791	4	0.025
cation transport	GO:0006812	399	0.025
peptide metabolic process	GO:0006518	46	0.024	Rat
morphogenesis of a branching structure	GO:0001763	203	0.024
digestive tract morphogenesis	GO:0048546	147	0.024
cardiac muscle tissue development	GO:0048738	130	0.024
posttranscriptional regulation of gene expression	GO:0010608	155	0.024
regulation of carbohydrate metabolic process	GO:0006109	75	0.024
organic hydroxy compound metabolic process	GO:1901615	203	0.024
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	GO:2000148	1	0.024
blood vessel endothelial cell migration	GO:0043534	23	0.024	Mouse
leukocyte migration	GO:0050900	124	0.024
negative regulation of wnt signaling pathway involved in heart development	GO:0003308	4	0.024
nucleoside phosphate catabolic process	GO:1901292	222	0.024
regulation of intracellular transport	GO:0032386	159	0.024
protein localization to membrane	GO:0072657	108	0.024
transmembrane transport	GO:0055085	412	0.023
regulation of ras protein signal transduction	GO:0046578	114	0.023
positive regulation of intracellular transport	GO:0032388	70	0.023
cellular response to dna damage stimulus	GO:0006974	207	0.023
platelet derived growth factor receptor signaling pathway	GO:0048008	32	0.023
tissue homeostasis	GO:0001894	115	0.023
cellular response to insulin stimulus	GO:0032869	78	0.023
negative regulation of protein modification process	GO:0031400	163	0.023
acylglycerol metabolic process	GO:0006639	55	0.023	Mouse
regulation of wnt signaling pathway	GO:0030111	123	0.023
nucleocytoplasmic transport	GO:0006913	139	0.023
basement membrane assembly	GO:0070831	2	0.023
organ regeneration	GO:0031100	2	0.023
cellular response to glucose stimulus	GO:0071333	45	0.023
cell junction organization	GO:0034330	77	0.022
regulation of neuron differentiation	GO:0045664	281	0.022
respiratory system development	GO:0060541	190	0.022
purine nucleotide metabolic process	GO:0006163	302	0.022
tissue migration	GO:0090130	68	0.022	Mouse
action potential	GO:0001508	78	0.022
hormone metabolic process	GO:0042445	86	0.022
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.022
tissue remodeling	GO:0048771	102	0.022
response to steroid hormone	GO:0048545	56	0.022	Rat
germ cell development	GO:0007281	185	0.022
negative regulation of growth	GO:0045926	99	0.022
ribonucleotide metabolic process	GO:0009259	291	0.021
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.021	Mouse
endothelial cell development	GO:0001885	20	0.021	Mouse
regulation of protein transport	GO:0051223	163	0.021
cell proliferation involved in outflow tract morphogenesis	GO:0061325	4	0.021
protein modification by small protein conjugation	GO:0032446	187	0.021
stem cell maintenance	GO:0019827	130	0.021
camera type eye development	GO:0043010	266	0.021
positive regulation of programmed cell death	GO:0043068	218	0.021
regulation of lipid biosynthetic process	GO:0046890	54	0.021
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.021
regulation of blood circulation	GO:1903522	93	0.021
forebrain radial glial cell differentiation	GO:0021861	4	0.021
ribonucleotide catabolic process	GO:0009261	208	0.021
negative regulation of platelet derived growth factor receptor signaling pathway	GO:0010642	7	0.021
response to molecule of bacterial origin	GO:0002237	143	0.021
glycolipid metabolic process	GO:0006664	25	0.021
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	GO:2000149	1	0.021
positive regulation of homeostatic process	GO:0032846	64	0.021
digestive tract development	GO:0048565	190	0.020
male gamete generation	GO:0048232	285	0.020
organophosphate biosynthetic process	GO:0090407	122	0.020
immune effector process	GO:0002252	321	0.020
protein import into nucleus	GO:0006606	95	0.020
regulation of cellular component biogenesis	GO:0044087	181	0.020
establishment of tissue polarity	GO:0007164	28	0.020
cellular response to carbohydrate stimulus	GO:0071322	50	0.020
platelet derived growth factor receptor alpha signaling pathway	GO:0035790	3	0.020
single organism nuclear import	GO:1902593	95	0.020
ribonucleoside metabolic process	GO:0009119	245	0.020
muscle system process	GO:0003012	141	0.020
type b pancreatic cell proliferation	GO:0044342	10	0.020
inorganic cation transmembrane transport	GO:0098662	207	0.020
purine containing compound catabolic process	GO:0072523	213	0.020
purine ribonucleoside metabolic process	GO:0046128	241	0.020
negative regulation of cell development	GO:0010721	169	0.020
intracellular cholesterol transport	GO:0032367	3	0.019
lipid localization	GO:0010876	126	0.019
bone morphogenesis	GO:0060349	78	0.019
response to lipopolysaccharide	GO:0032496	128	0.019
coagulation	GO:0050817	78	0.019
rho protein signal transduction	GO:0007266	32	0.019
lipid catabolic process	GO:0016042	69	0.019
skeletal system development	GO:0001501	356	0.019
response to decreased oxygen levels	GO:0036293	59	0.019
endothelial cell apoptotic process	GO:0072577	9	0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	61	0.019
male sex differentiation	GO:0046661	109	0.019
connective tissue development	GO:0061448	179	0.019
regulation of bone remodeling	GO:0046850	28	0.019
ribose phosphate metabolic process	GO:0019693	291	0.019
negative regulation of phosphate metabolic process	GO:0045936	184	0.019
response to growth factor	GO:0070848	198	0.019
cell cell junction organization	GO:0045216	72	0.019
regulation of body fluid levels	GO:0050878	162	0.019
regulation of cell activation	GO:0050865	289	0.019
forebrain cell migration	GO:0021885	58	0.019
fatty acid metabolic process	GO:0006631	121	0.019
carbohydrate biosynthetic process	GO:0016051	74	0.019
limb morphogenesis	GO:0035108	149	0.019
endocytosis	GO:0006897	168	0.018
regulation of intracellular protein transport	GO:0033157	82	0.018
cellular response to hexose stimulus	GO:0071331	47	0.018
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.018
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	GO:2000164	1	0.018
regulation of transmembrane transport	GO:0034762	128	0.018
bone resorption	GO:0045453	38	0.018
negative regulation of defense response	GO:0031348	77	0.018	Mouse
regulation of cytokine production	GO:0001817	266	0.018
protein hydroxylation	GO:0018126	4	0.018
cellular lipid catabolic process	GO:0044242	52	0.018
kidney epithelium development	GO:0072073	121	0.018
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.018
actin filament organization	GO:0007015	113	0.018
cellular response to starvation	GO:0009267	57	0.018
energy derivation by oxidation of organic compounds	GO:0015980	77	0.018
maintenance of location	GO:0051235	89	0.018
bone development	GO:0060348	120	0.018
carbohydrate transport	GO:0008643	62	0.017
regulation of cellular response to oxidative stress	GO:1900407	19	0.017	Mouse
nucleoside triphosphate metabolic process	GO:0009141	230	0.017
negative regulation of planar cell polarity pathway involved in heart morphogenesis	GO:2000160	1	0.017
generation of precursor metabolites and energy	GO:0006091	103	0.017
regulation of peptide hormone secretion	GO:0090276	75	0.017
embryonic appendage morphogenesis	GO:0035113	126	0.017
cellular component assembly involved in morphogenesis	GO:0010927	139	0.017
liposaccharide metabolic process	GO:1903509	27	0.017
embryonic epithelial tube formation	GO:0001838	130	0.017
cardiac chamber development	GO:0003205	108	0.017
canonical wnt signaling pathway	GO:0060070	130	0.017
regulation of fatty acid metabolic process	GO:0019217	28	0.017
hexose transport	GO:0008645	56	0.017
monosaccharide transport	GO:0015749	58	0.017
sensory organ morphogenesis	GO:0090596	242	0.017
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	GO:2000161	1	0.017
ras protein signal transduction	GO:0007265	77	0.017
development of primary male sexual characteristics	GO:0046546	88	0.017
stem cell development	GO:0048864	219	0.017
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	GO:0061310	1	0.017
regulation of cell cycle process	GO:0010564	160	0.017
heart morphogenesis	GO:0003007	178	0.017
positive regulation of cell development	GO:0010720	237	0.016
negative regulation of smooth muscle cell migration	GO:0014912	2	0.016
canonical wnt signaling pathway involved in neural crest cell differentiation	GO:0044335	1	0.016
regulation of angiotensin metabolic process	GO:0060177	4	0.016
cellular amide metabolic process	GO:0043603	58	0.016	Rat
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.016
skeletal system morphogenesis	GO:0048705	203	0.016
purine nucleoside catabolic process	GO:0006152	205	0.016
small molecule catabolic process	GO:0044282	71	0.016
molting cycle	GO:0042303	90	0.016
hindbrain morphogenesis	GO:0021575	46	0.016
negative regulation of fat cell differentiation	GO:0045599	36	0.016
regulation of ion transport	GO:0043269	215	0.016
sprouting angiogenesis	GO:0002040	26	0.016
regulation of peptidyl serine phosphorylation	GO:0033135	39	0.016
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.016
nucleoside triphosphate catabolic process	GO:0009143	205	0.016
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.016
response to osmotic stress	GO:0006970	21	0.016
negative regulation of epithelial cell proliferation	GO:0050680	64	0.016
positive regulation of hormone secretion	GO:0046887	38	0.016
nucleoside catabolic process	GO:0009164	206	0.016
developmental growth involved in morphogenesis	GO:0060560	138	0.015
establishment of planar polarity	GO:0001736	28	0.015
positive regulation of cell motility	GO:2000147	116	0.015
response to estrogen	GO:0043627	24	0.015
cholesterol metabolic process	GO:0008203	56	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.015
intrinsic apoptotic signaling pathway in response to oxidative stress	GO:0008631	19	0.015	Mouse
carbohydrate derivative catabolic process	GO:1901136	231	0.015
cyclic nucleotide metabolic process	GO:0009187	59	0.015
positive regulation of lipid metabolic process	GO:0045834	40	0.015
regulation of systemic arterial blood pressure by renin angiotensin	GO:0003081	20	0.015
mitotic cell cycle process	GO:1903047	159	0.015
plasma membrane organization	GO:0007009	90	0.015
regulation of smad protein import into nucleus	GO:0060390	3	0.015
purine ribonucleotide metabolic process	GO:0009150	290	0.015
positive regulation of protein transport	GO:0051222	93	0.015
sterol metabolic process	GO:0016125	58	0.015
small molecule biosynthetic process	GO:0044283	132	0.015
regulation of cell projection organization	GO:0031344	206	0.015
muscle fiber development	GO:0048747	76	0.015	Mouse
cytokine production	GO:0001816	319	0.015
regulation of bmp signaling pathway	GO:0030510	60	0.015
axonogenesis	GO:0007409	274	0.015
cell chemotaxis	GO:0060326	81	0.015
striated muscle myosin thick filament assembly	GO:0071688	1	0.015
positive regulation of behavior	GO:0048520	40	0.015
response to starvation	GO:0042594	65	0.015
hair follicle development	GO:0001942	85	0.015
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transport	GO:0090118	1	0.015
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.015
negative regulation of response to oxidative stress	GO:1902883	10	0.015	Mouse
response to reactive oxygen species	GO:0000302	56	0.015
nucleoside metabolic process	GO:0009116	246	0.015
spermatid development	GO:0007286	108	0.015
morphogenesis of a polarized epithelium	GO:0001738	37	0.015
ear development	GO:0043583	200	0.015
establishment of protein localization to membrane	GO:0090150	54	0.015
regulation of phospholipid biosynthetic process	GO:0071071	3	0.015
response to alcohol	GO:0097305	48	0.015	Rat
negative regulation of cellular amine metabolic process	GO:0033239	1	0.015
tube formation	GO:0035148	140	0.015
cellular response to estrogen stimulus	GO:0071391	12	0.015
cellular macromolecule catabolic process	GO:0044265	206	0.015
retina development in camera type eye	GO:0060041	119	0.015
negative regulation of cellular component organization	GO:0051129	194	0.015
muscle cell migration	GO:0014812	19	0.015
regulation of peptide transport	GO:0090087	91	0.015
regeneration	GO:0031099	38	0.015	Mouse
cellular response to nutrient levels	GO:0031669	64	0.014
spermatid differentiation	GO:0048515	115	0.014
regulation of endothelial cell apoptotic process	GO:2000351	9	0.014
regulation of metanephric mesenchymal cell migration	GO:2000589	2	0.014
amino acid transmembrane transport	GO:0003333	37	0.014
regulation of lymphocyte differentiation	GO:0045619	107	0.014
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	34	0.014	Mouse
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.014
adherens junction organization	GO:0034332	28	0.014
female sex differentiation	GO:0046660	84	0.014
insulin secretion involved in cellular response to glucose stimulus	GO:0035773	36	0.014
embryonic limb morphogenesis	GO:0030326	126	0.014
acetylcholine transport	GO:0015870	2	0.014
cardiac muscle cell differentiation	GO:0055007	69	0.014
nucleotide biosynthetic process	GO:0009165	78	0.014
organic acid transport	GO:0015849	101	0.014
cell division	GO:0051301	120	0.014
multi multicellular organism process	GO:0044706	109	0.014	Rat
organelle assembly	GO:0070925	177	0.014
regulation of leukocyte differentiation	GO:1902105	159	0.014
inorganic ion transmembrane transport	GO:0098660	234	0.014
hair cycle	GO:0042633	90	0.014
negative regulation of cell growth	GO:0030308	44	0.014
regulation of ion transmembrane transport	GO:0034765	119	0.014
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.014
metal ion homeostasis	GO:0055065	189	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.014
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	GO:2000151	1	0.014

Gpx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.104
inherited metabolic disorder	DOID:655	0.074
immune system disease	DOID:2914	0.060
disease of anatomical entity	DOID:7	0.060
nervous system disease	DOID:863	0.025
hematopoietic system disease	DOID:74	0.023

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