Mus musculus

22 known processes

Igj

immunoglobulin joining chain

(Aliases: AI323815,Jch,9530090F24Rik)

Igj biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
stimulatory c type lectin receptor signaling pathwayGO:000222320.518
activation of immune responseGO:00022531380.236
hematopoietic stem cell migrationGO:003570110.141
positive regulation of immunological synapse formationGO:200052210.111
microglial cell activation involved in immune responseGO:000228210.108
positive regulation of t cell receptor signaling pathwayGO:005086240.106
immune response activating signal transductionGO:00027571160.103
membrane organizationGO:00610242450.091
cellular ketone metabolic processGO:0042180840.090
regulation of lymphocyte activationGO:00512492400.089
second messenger mediated signalingGO:0019932730.084
innate immune response activating cell surface receptor signaling pathwayGO:000222040.083
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.078
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationGO:200052610.074
helper t cell chemotaxisGO:003570410.073
cellular response to molecule of bacterial originGO:0071219830.069
leukocyte chemotaxisGO:0030595690.066
inflammatory responseGO:00069542440.066
eosinophil activation involved in immune responseGO:000227810.065
cellular amino acid metabolic processGO:00065201030.064
positive regulation of cell activationGO:00508671580.064
monocyte extravasationGO:003569620.063
positive regulation of t cell activationGO:00508701010.060
regulation of cellular amine metabolic processGO:0033238200.060
cd8 positive alpha beta t cell extravasationGO:003569730.060
detection of yeastGO:000187920.060
chemokine mediated signaling pathwayGO:0070098170.058
amine metabolic processGO:0009308450.058
cell chemotaxisGO:0060326810.057
regulation of vesicle mediated transportGO:00606271390.056
regulation of synaptic growth at neuromuscular junctionGO:000858240.056
cellular response to molecule of fungal originGO:007122620.056
regulation of reactive oxygen species biosynthetic processGO:190342620.056
nucleotide metabolic processGO:00091173320.055
sensory perceptionGO:00076002450.055
cation transportGO:00068123990.052
positive regulation of t cell extravasationGO:200040920.051
cellular lipid metabolic processGO:00442553230.050
microglial cell activationGO:000177430.049
negative regulation of eosinophil degranulationGO:004331010.049
leukocyte mediated cytotoxicityGO:0001909620.049
cellular amine metabolic processGO:0044106440.048
detection of stimulusGO:0051606840.047
response to molecule of fungal originGO:000223840.047
cell surface pattern recognition receptor signaling pathwayGO:000275220.046
regulation of t cell activationGO:00508631700.046
positive regulation of t cell costimulationGO:200052520.046
cellular response to lipidGO:00713961450.046
microglia differentiationGO:001400420.045
eosinophil activationGO:004330710.045
regulation of response to woundingGO:19030341890.044
circulatory system processGO:00030131970.044
organophosphate biosynthetic processGO:00904071220.044
regulation of eosinophil degranulationGO:004330910.044
microglia developmentGO:001400520.044
thymic t cell selectionGO:0045061220.043
regulation of immune complex clearance by monocytes and macrophagesGO:009026420.043
positive regulation of inflammatory responseGO:0050729470.042
ribose phosphate metabolic processGO:00196932910.042
regulation of t cell costimulationGO:200052320.042
cellular homeostasisGO:00197252400.041
apoptotic signaling pathwayGO:00971903060.041
detection of fungusGO:001604620.040
positive regulation of cellular amine metabolic processGO:003324050.040
positive regulation of alpha beta t cell activationGO:0046635390.040
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.040
eosinophil mediated immunityGO:000244710.039
regulation of cellular amino acid metabolic processGO:000652150.039
blood circulationGO:00080151950.039
myeloid cell differentiationGO:00300992330.039
ion transmembrane transportGO:00342203610.038
regulation of endocytosisGO:0030100690.038
regulation of immunological synapse formationGO:200052020.037
immune effector processGO:00022523210.037
t helper 17 cell chemotaxisGO:003570510.037
regulation of cellular ketone metabolic processGO:0010565660.037
positive regulation of hematopoietic stem cell migrationGO:200047310.036
positive regulation of defense responseGO:00313491240.035
divalent inorganic cation transportGO:00725111780.035
regulation of monocyte extravasationGO:200043720.035
antigen receptor mediated signaling pathwayGO:0050851640.035
t cell extravasationGO:007268340.034
positive regulation of leukocyte differentiationGO:1902107860.034
nucleobase containing small molecule metabolic processGO:00550863520.033
blood vessel morphogenesisGO:00485142850.033
immune complex clearance by monocytes and macrophagesGO:000243620.033
innate immune responseGO:00450871570.032
Human
purine containing compound metabolic processGO:00725213110.032
nitrogen compound transportGO:00717052710.032
fatty acid metabolic processGO:00066311210.032
adaptive immune responseGO:00022501550.032
Human
maintenance of locationGO:0051235890.031
lymphocyte mediated immunityGO:00024491390.031
tissue remodelingGO:00487711020.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
regulation of t cell extravasationGO:200040730.031
cell recognitionGO:0008037830.030
positive regulation of monocyte extravasationGO:200043910.030
aromatic compound catabolic processGO:00194392860.030
calcium mediated signalingGO:0019722460.029
neuron migrationGO:00017641220.029
regulation of cell activationGO:00508652890.029
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.029
forebrain developmentGO:00309003020.029
leukocyte migrationGO:00509001240.029
negative regulation of protein metabolic processGO:00512482820.029
regulation of dendritic cell chemotaxisGO:200050810.029
axonogenesisGO:00074092740.029
endocytosisGO:00068971680.028
cell adhesionGO:00071553290.028
cyclic nucleotide metabolic processGO:0009187590.028
interleukin 12 secretionGO:007261030.028
neutrophil migrationGO:1990266370.028
leukocyte mediated immunityGO:00024431740.028
g protein coupled receptor signaling pathwayGO:00071862430.028
positive regulation of cell developmentGO:00107202370.028
multicellular organismal signalingGO:0035637910.027
positive regulation of bone remodelingGO:0046852130.027
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.027
peptidyl amino acid modificationGO:00181933360.027
regulation of cell motilityGO:20001452360.027
regulation of myeloid cell differentiationGO:0045637960.027
positive regulation of lymphocyte activationGO:00512511400.027
positive regulation of homeostatic processGO:0032846640.027
positive regulation of dendritic cell chemotaxisGO:200051010.027
positive regulation of leukocyte mediated immunityGO:0002705700.027
cell killingGO:0001906670.027
immune response regulating signaling pathwayGO:00027641250.027
cytokine productionGO:00018163190.026
carbohydrate derivative biosynthetic processGO:19011371830.026
purine ribonucleotide metabolic processGO:00091502900.026
regulation of hematopoietic stem cell migrationGO:200047110.026
angiogenesisGO:00015252010.026
thermosensory behaviorGO:004004010.026
cognitionGO:00508901490.025
response to extracellular stimulusGO:00099911270.025
organic cyclic compound catabolic processGO:19013612950.025
regulation of inflammatory response to antigenic stimulusGO:0002861210.025
rho protein signal transductionGO:0007266320.025
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.025
acute inflammatory response to antigenic stimulusGO:0002438120.025
leukocyte differentiationGO:00025213420.025
regulation of chloride transportGO:200122520.024
neural precursor cell proliferationGO:00613511210.024
response to organic cyclic compoundGO:00140701980.024
immune complex clearanceGO:000243420.024
regulation of antigen receptor mediated signaling pathwayGO:0050854290.024
negative regulation of macrophage apoptotic processGO:200011030.024
regulation of cyclic nucleotide metabolic processGO:0030799400.023
macrophage activationGO:0042116270.023
adult behaviorGO:00305341350.023
regulation of hormone levelsGO:00108172110.023
oxidation reduction processGO:00551143420.023
regulation of homeostatic processGO:00328441820.023
regulation of blood pressureGO:0008217930.023
positive regulation of immune complex clearance by monocytes and macrophagesGO:009026520.023
t cell differentiationGO:00302171740.023
cellular response to cytokine stimulusGO:00713451890.023
lymphocyte differentiationGO:00300982420.023
regulation of angiotensin levels in bloodGO:000200240.022
protein catabolic processGO:00301632210.022
alcohol metabolic processGO:00060661160.022
granulocyte chemotaxisGO:0071621390.022
antigen processing and presentationGO:0019882470.022
response to molecule of bacterial originGO:00022371430.022
immune response regulating cell surface receptor signaling pathwayGO:0002768800.022
humoral immune responseGO:0006959570.022
Human
lipid biosynthetic processGO:00086101790.021
t cell receptor signaling pathwayGO:0050852460.021
fatty acid biosynthetic processGO:0006633410.021
cellular chemical homeostasisGO:00550822150.021
neuron projection guidanceGO:00974851410.021
ribonucleotide metabolic processGO:00092592910.021
ras protein signal transductionGO:0007265770.021
macromolecule catabolic processGO:00090572810.021
regulation of leukocyte proliferationGO:00706631210.021
positive regulation of protein phosphorylationGO:00019342420.021
regulation of monocyte chemotaxisGO:009002530.021
monocarboxylic acid metabolic processGO:00327871910.020
leukocyte degranulationGO:0043299270.020
cytokine mediated signaling pathwayGO:00192211150.020
regulation of defense responseGO:00313472330.020
organonitrogen compound biosynthetic processGO:19015661920.020
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiationGO:200072120.020
positive regulation of lymphocyte anergyGO:000291340.020
positive regulation of reactive oxygen species biosynthetic processGO:190342820.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
positive regulation of cell deathGO:00109422240.020
transforming growth factor beta receptor signaling pathwayGO:0007179710.020
immune response activating cell surface receptor signaling pathwayGO:0002429720.020
myeloid leukocyte migrationGO:0097529570.019
nucleoside phosphate metabolic processGO:00067533380.019
germ cell developmentGO:00072811850.019
fat cell differentiationGO:00454441600.019
eosinophil degranulationGO:004330810.019
glycoprotein biosynthetic processGO:0009101890.019
chemotaxisGO:00069352470.019
carboxylic acid biosynthetic processGO:0046394860.019
regulation of apoptotic signaling pathwayGO:20012331970.019
innate immune response activating signal transductionGO:0002758500.019
single organism cell adhesionGO:00986021560.019
metal ion homeostasisGO:00550651890.019
branching morphogenesis of an epithelial tubeGO:00487541590.018
regulation of ion transportGO:00432692150.018
purine nucleotide metabolic processGO:00061633020.018
plasma membrane organizationGO:0007009900.018
reactive nitrogen species metabolic processGO:200105700.018
negative regulation of cellular component organizationGO:00511291940.018
positive regulation of cell adhesionGO:0045785800.018
extrinsic apoptotic signaling pathwayGO:00971911260.018
regulation of chemotaxisGO:0050920530.018
cyclic nucleotide biosynthetic processGO:0009190440.018
regulation of cell projection organizationGO:00313442060.018
alpha beta t cell activationGO:0046631910.017
localization within membraneGO:005166840.017
regulation of acute inflammatory responseGO:0002673270.017
transmembrane transportGO:00550854120.017
transmission of nerve impulseGO:0019226760.017
positive regulation of reactive oxygen species metabolic processGO:2000379110.017
regulation of inflammatory responseGO:00507271470.017
amino acid transportGO:0006865610.017
regulation of macrophage activationGO:0043030170.017
divalent metal ion transportGO:00708381720.017
positive regulation of cell killingGO:0031343330.017
cytoplasmic transportGO:00164822340.017
single organismal cell cell adhesionGO:00163371310.017
positive regulation of monocyte chemotaxisGO:009002620.017
positive regulation of calcium mediated signalingGO:0050850150.017
positive regulation of lymphocyte proliferationGO:0050671700.017
positive regulation of nervous system developmentGO:00519622210.016
response to lipopolysaccharideGO:00324961280.016
positive regulation of cytokine productionGO:00018191740.016
signal transduction in absence of ligandGO:0038034550.016
axon guidanceGO:00074111410.016
cellular ion homeostasisGO:00068731650.016
regulation of nucleotide metabolic processGO:00061401690.016
dendritic spine maintenanceGO:009706240.016
regulation of purine nucleotide metabolic processGO:19005421690.016
acute inflammatory responseGO:0002526410.016
regulation of phagocytosisGO:0050764330.016
natural killer cell mediated immunityGO:0002228290.016
lymphocyte proliferationGO:00466511640.016
regulation of t cell proliferationGO:0042129920.016
cellular macromolecule catabolic processGO:00442652060.016
negative thymic t cell selectionGO:0045060120.016
negative regulation of vasculature developmentGO:1901343260.015
small gtpase mediated signal transductionGO:0007264970.015
negative regulation of cell migrationGO:0030336590.015
epithelial tube morphogenesisGO:00605623030.015
small molecule biosynthetic processGO:00442831320.015
granulocyte activationGO:0036230100.015
male gamete generationGO:00482322850.015
anion transmembrane transportGO:0098656710.015
positive regulation of neutrophil mediated killing of symbiont cellGO:007096110.015
chloride transportGO:0006821320.015
multicellular organismal homeostasisGO:00488711640.015
Human
regulation of cell adhesionGO:00301551540.015
regulation of leukocyte mediated immunityGO:00027031040.015
response to peptide hormoneGO:00434341270.015
carbohydrate homeostasisGO:00335001280.015
response to oxidative stressGO:00069791230.015
regulation of membrane potentialGO:00423911920.014
sequestering of calcium ionGO:0051208180.014
cellular calcium ion homeostasisGO:00068741190.014
cellular carbohydrate metabolic processGO:00442621190.014
inorganic ion transmembrane transportGO:00986602340.014
protein localization to nucleusGO:00345041210.014
anion transportGO:00068201770.014
b cell activationGO:00421131610.014
muscle tissue developmentGO:00605373080.014
regulation of type 2 immune responseGO:0002828180.014
membrane invaginationGO:0010324170.014
organic hydroxy compound metabolic processGO:19016152030.014
bone resorptionGO:0045453380.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
sulfur compound metabolic processGO:00067901000.014
regulation of cellular component biogenesisGO:00440871810.014
reactive oxygen species metabolic processGO:0072593840.014
regulation of vasculature developmentGO:1901342880.014
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.014
positive regulation of phagocytosisGO:0050766260.013
cellular metal ion homeostasisGO:00068751510.013
positive regulation of interleukin 2 productionGO:0032743190.013
cytosolic calcium ion homeostasisGO:0051480700.013
neuronal action potentialGO:0019228540.013
cell cell recognitionGO:0009988440.013
leukocyte proliferationGO:00706611720.013
negative regulation of synapse assemblyGO:005196430.013
phagocytosisGO:0006909660.013
positive regulation of kinase activityGO:00336741550.013
morphogenesis of a branching epitheliumGO:00611381930.013
regulation of epithelial cell proliferationGO:00506781410.013
substrate dependent cell migrationGO:0006929180.013
regulation of organelle organizationGO:00330432890.013
carbohydrate metabolic processGO:00059752300.013
negative regulation of immune system processGO:00026832090.013
brown fat cell differentiationGO:0050873360.013
positive regulation of intracellular transportGO:0032388700.013
epithelial cell proliferationGO:00506731740.013
interferon gamma productionGO:0032609670.013
mature dendritic cell differentiationGO:009702930.013
memoryGO:0007613580.013
interleukin 2 productionGO:0032623330.013
regulation of anatomical structure sizeGO:00900661780.013
cellular protein catabolic processGO:00442571550.013
negative regulation of phospholipase activityGO:001051940.013
negative regulation of growthGO:0045926990.013
cation transmembrane transportGO:00986552660.013
microtubule based processGO:00070172360.013
protein localization to organelleGO:00333651850.013
positive regulation of endocytosisGO:0045807420.012
regulation of tissue remodelingGO:0034103380.012
positive regulation of camp mediated signalingGO:004395030.012
regulation of interleukin 2 productionGO:0032663280.012
regulation of cellular catabolic processGO:00313292420.012
cerebral cortex developmentGO:0021987860.012
positive regulation of response to woundingGO:1903036660.012
positive regulation of cell motilityGO:20001471160.012
regulation of hydrolase activityGO:00513362460.012
negative regulation of molecular functionGO:00440922580.012
regulation of intracellular transportGO:00323861590.012
regulation of lymphocyte mediated immunityGO:0002706840.012
sensory organ morphogenesisGO:00905962420.012
cytokine biosynthetic processGO:0042089680.012
cerebral cortex cell migrationGO:0021795440.012
ribonucleotide biosynthetic processGO:0009260590.012
negative regulation of angiogenesisGO:0016525250.012
engulfment of apoptotic cellGO:004365230.012
t cell selectionGO:0045058340.012
regulation of interferon gamma productionGO:0032649570.012
positive thymic t cell selectionGO:0045059130.012
cellular response to transforming growth factor beta stimulusGO:0071560880.012
response to drugGO:0042493750.012
renal system developmentGO:00720012250.012
antigen processing and presentation of exogenous antigenGO:0019884260.012
lipid homeostasisGO:0055088630.012
reactive oxygen species biosynthetic processGO:190340980.012
regulation of lymphocyte differentiationGO:00456191070.012
positive regulation of immune effector processGO:00026991070.012
kidney developmentGO:00018222130.011
b cell mediated immunityGO:0019724710.011
granulocyte migrationGO:0097530430.011
positive regulation of natural killer cell mediated immunityGO:0002717160.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
neuromuscular processGO:0050905990.011
positive regulation of cell migrationGO:00303351090.011
regulation of neuron differentiationGO:00456642810.011
peptidyl tyrosine modificationGO:00182121450.011
ameboidal type cell migrationGO:00016671280.011
positive regulation of lymphocyte differentiationGO:0045621610.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.011
positive regulation of apoptotic processGO:00430652170.011
ribonucleoside metabolic processGO:00091192450.011
regulation of lymphocyte proliferationGO:00506701170.011
antibacterial humoral responseGO:001973180.011
Human
nucleoside phosphate catabolic processGO:19012922220.011
positive regulation of map kinase activityGO:0043406840.011
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.011
glucose homeostasisGO:00425931280.011
mapk cascadeGO:00001652810.011
organophosphate catabolic processGO:00464342320.011
nucleoside phosphate biosynthetic processGO:1901293790.011
defense response to bacteriumGO:00427421190.011
Human
calcium ion homeostasisGO:00550741270.011
nucleotide biosynthetic processGO:0009165780.011
bone remodelingGO:0046849530.011
inorganic anion transportGO:0015698430.011
extracellular matrix organizationGO:00301981470.011
integrin activationGO:003362280.011
inflammatory response to antigenic stimulusGO:0002437300.011
neutrophil chemotaxisGO:0030593360.011
peptide transportGO:00158331330.011
positive regulation of bone resorptionGO:0045780130.011
cell adhesion mediated by integrinGO:0033627180.011
regulation of adaptive immune responseGO:0002819900.011
gliogenesisGO:00420631410.011
locomotory behaviorGO:00076261950.010
compound eye developmentGO:004874910.010
positive regulation of leukocyte proliferationGO:0070665730.010
learning or memoryGO:00076111480.010
phagocytosis recognitionGO:0006910120.010
steroid metabolic processGO:00082021190.010
sterol metabolic processGO:0016125580.010
regulation of type ii hypersensitivityGO:000289240.010
exocytosisGO:00068871210.010
negative regulation of cellular amine metabolic processGO:003323910.010
divalent inorganic cation homeostasisGO:00725071380.010
respiratory system developmentGO:00605411900.010
regulation of lymphocyte anergyGO:000291140.010
negative regulation of signal transduction in absence of ligandGO:1901099160.010
positive regulation of type ii hypersensitivityGO:000289440.010
regulation of reactive oxygen species metabolic processGO:2000377400.010
regulation of cell killingGO:0031341400.010
chromatin organizationGO:00063252060.010
regulation of leukocyte differentiationGO:19021051590.010
positive regulation of eosinophil migrationGO:200041820.010
cation homeostasisGO:00550802120.010

Igj disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hematopoietic system diseaseDOID:7400.331
immune system diseaseDOID:291400.331
disease of anatomical entityDOID:700.331
primary immunodeficiency diseaseDOID:61200.059
sensory system diseaseDOID:005015500.034
nervous system diseaseDOID:86300.034
eye and adnexa diseaseDOID:149200.034
blood protein diseaseDOID:62000.032
eye diseaseDOID:561400.027
b cell deficiencyDOID:211500.026
retinal diseaseDOID:567900.012
retinal degenerationDOID:846600.012
disease of metabolismDOID:001466700.012