Mus musculus

76 known processes

Hpse

heparanase

(Aliases: HSE1,Hpa,Hpr1)

Hpse biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleobase containing small molecule metabolic processGO:00550863520.081
immune effector processGO:00022523210.076
regulation of cell activationGO:00508652890.069
nucleoside phosphate metabolic processGO:00067533380.068
membrane organizationGO:00610242450.062
regulation of cytokine productionGO:00018172660.057
regulation of hydrolase activityGO:00513362460.056
heterocycle catabolic processGO:00467002800.055
t cell activationGO:00421102890.055
regulation of lymphocyte activationGO:00512492400.054
cellular nitrogen compound catabolic processGO:00442702800.053
cellular amino acid metabolic processGO:00065201030.049
purine containing compound catabolic processGO:00725232130.048
purine nucleotide metabolic processGO:00061633020.047
immune response regulating signaling pathwayGO:00027641250.047
adaptive immune responseGO:00022501550.047
negative regulation of phosphorus metabolic processGO:00105631840.047
regulation of cellular ketone metabolic processGO:0010565660.046
regulation of cellular amino acid metabolic processGO:000652150.045
purine containing compound metabolic processGO:00725213110.045
cytokine productionGO:00018163190.045
nucleoside catabolic processGO:00091642060.045
negative regulation of cellular protein metabolic processGO:00322692470.044
purine nucleoside triphosphate metabolic processGO:00091442260.043
macromolecule catabolic processGO:00090572810.042
response to organonitrogen compoundGO:00102432460.042
organic cyclic compound catabolic processGO:19013612950.042
purine ribonucleoside triphosphate catabolic processGO:00092071990.041
cellular chemical homeostasisGO:00550822150.041
activation of immune responseGO:00022531380.041
cellular amine metabolic processGO:0044106440.041
leukocyte mediated immunityGO:00024431740.041
cation transportGO:00068123990.041
lymphocyte mediated immunityGO:00024491390.040
carbohydrate derivative catabolic processGO:19011362310.040
innate immune responseGO:00450871570.040
nucleoside phosphate catabolic processGO:19012922220.040
purine ribonucleoside metabolic processGO:00461282410.039
regulation of membrane potentialGO:00423911920.039
cell adhesionGO:00071553290.039
response to organic cyclic compoundGO:00140701980.038
purine ribonucleotide catabolic processGO:00091542080.038
ribonucleoside catabolic processGO:00424542060.038
transmembrane transportGO:00550854120.036
spermatogenesisGO:00072832840.036
male gamete generationGO:00482322850.036
negative regulation of cell proliferationGO:00082852960.035
ribonucleoside metabolic processGO:00091192450.035
small gtpase mediated signal transductionGO:0007264970.035
regulation of cellular amine metabolic processGO:0033238200.035
positive regulation of cellular amine metabolic processGO:003324050.035
nucleoside metabolic processGO:00091162460.035
regulation of t cell activationGO:00508631700.035
carbohydrate metabolic processGO:00059752300.034
nucleoside triphosphate metabolic processGO:00091412300.034
purine nucleoside triphosphate catabolic processGO:00091462030.034
nucleoside triphosphate catabolic processGO:00091432050.034
nucleotide metabolic processGO:00091173320.034
multicellular organismal homeostasisGO:00488711640.034
organonitrogen compound catabolic processGO:19015652640.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.033
negative regulation of protein metabolic processGO:00512482820.033
purine nucleoside metabolic processGO:00422782410.033
regulation of secretionGO:00510462740.032
purine ribonucleoside triphosphate metabolic processGO:00092052200.032
ribose phosphate metabolic processGO:00196932910.032
anion transportGO:00068201770.032
ribonucleoside triphosphate metabolic processGO:00091992200.032
purine ribonucleoside catabolic processGO:00461302050.032
cellular ketone metabolic processGO:0042180840.031
regulation of system processGO:00440572000.031
nitrogen compound transportGO:00717052710.031
mapk cascadeGO:00001652810.030
glycosyl compound metabolic processGO:19016572460.030
positive regulation of cell deathGO:00109422240.030
regulation of mapk cascadeGO:00434082480.030
cell type specific apoptotic processGO:00972852680.029
purine ribonucleotide metabolic processGO:00091502900.029
ion transmembrane transportGO:00342203610.029
amine metabolic processGO:0009308450.029
cellular lipid metabolic processGO:00442553230.028
immune response activating signal transductionGO:00027571160.028
positive regulation of protein modification processGO:00314012990.028
ribonucleotide metabolic processGO:00092592910.028
cellular response to cytokine stimulusGO:00713451890.028
organophosphate catabolic processGO:00464342320.028
cellular homeostasisGO:00197252400.028
negative regulation of immune system processGO:00026832090.028
organonitrogen compound biosynthetic processGO:19015661920.027
metal ion homeostasisGO:00550651890.027
aromatic compound catabolic processGO:00194392860.027
glycosyl compound catabolic processGO:19016582060.027
inflammatory responseGO:00069542440.027
leukocyte differentiationGO:00025213420.027
nucleotide catabolic processGO:00091662170.027
reactive oxygen species metabolic processGO:0072593840.027
oxidation reduction processGO:00551143420.026
regulation of kinase activityGO:00435492490.026
purine nucleoside catabolic processGO:00061522050.026
regulation of defense responseGO:00313472330.025
cell killingGO:0001906670.025
cellular metal ion homeostasisGO:00068751510.025
fat cell differentiationGO:00454441600.025
purine nucleotide catabolic processGO:00061952110.025
myeloid cell differentiationGO:00300992330.025
calcium ion transportGO:00068161590.024
peptidyl amino acid modificationGO:00181933360.024
carbohydrate derivative biosynthetic processGO:19011371830.024
regulation of cellular catabolic processGO:00313292420.024
positive regulation of defense responseGO:00313491240.024
regulation of transferase activityGO:00513382630.024
homeostasis of number of cellsGO:00488722100.024
muscle system processGO:00030121410.024
skeletal system developmentGO:00015013560.024
cellular response to lipopolysaccharideGO:0071222770.024
regulation of innate immune responseGO:0045088910.024
regulation of protein kinase activityGO:00458592320.024
ribonucleoside triphosphate catabolic processGO:00092031990.024
protein maturationGO:00516041760.023
ras protein signal transductionGO:0007265770.023
single organism cell adhesionGO:00986021560.023
cytoplasmic transportGO:00164822340.023
lipid biosynthetic processGO:00086101790.023
positive regulation of programmed cell deathGO:00430682180.023
negative regulation of cell activationGO:00508661110.023
leukocyte proliferationGO:00706611720.023
g protein coupled receptor signaling pathwayGO:00071862430.023
toll like receptor signaling pathwayGO:0002224380.023
defense response to other organismGO:00985421970.023
cellular response to organonitrogen compoundGO:00714171450.022
epidermis developmentGO:00085441870.022
cellular ion homeostasisGO:00068731650.022
response to molecule of bacterial originGO:00022371430.022
regulation of organelle organizationGO:00330432890.022
regulation of apoptotic signaling pathwayGO:20012331970.022
cellular response to molecule of bacterial originGO:0071219830.022
negative regulation of intracellular signal transductionGO:19025321670.021
regulation of ion transportGO:00432692150.021
regulation of secretion by cellGO:19035302490.021
action potentialGO:0001508780.021
positive regulation of apoptotic signaling pathwayGO:2001235950.021
defense response to bacteriumGO:00427421190.021
cell activation involved in immune responseGO:00022631260.021
ribonucleotide catabolic processGO:00092612080.021
myeloid leukocyte differentiationGO:00025731190.021
ossificationGO:00015032160.021
positive regulation of apoptotic processGO:00430652170.020
regulation of map kinase activityGO:00434051200.020
gland developmentGO:00487323300.020
regulation of proteolysisGO:00301621640.020
fertilizationGO:00095661270.020
lymphocyte proliferationGO:00466511640.020
protein catabolic processGO:00301632210.020
organic anion transportGO:00157111370.020
multicellular organismal signalingGO:0035637910.020
sensory perceptionGO:00076002450.020
regulation of leukocyte proliferationGO:00706631210.020
natural killer cell activationGO:0030101440.019
regulation of hormone levelsGO:00108172110.019
cellular response to lipidGO:00713961450.019
regulation of nucleotide metabolic processGO:00061401690.019
glycoprotein metabolic processGO:00091001160.019
cytokine mediated signaling pathwayGO:00192211150.019
divalent inorganic cation transportGO:00725111780.019
posttranscriptional regulation of gene expressionGO:00106081550.019
regulation of lymphocyte proliferationGO:00506701170.019
positive regulation of cytokine productionGO:00018191740.019
regulation of protein localizationGO:00328802310.019
regulation of multi organism processGO:00439001110.019
positive regulation of innate immune responseGO:0045089800.019
cellular macromolecule catabolic processGO:00442652060.019
leukocyte activation involved in immune responseGO:00023661260.019
myeloid leukocyte activationGO:0002274830.019
muscle cell differentiationGO:00426922610.019
response to radiationGO:00093141650.019
regulation of purine nucleotide metabolic processGO:19005421690.019
transmission of nerve impulseGO:0019226760.018
negative regulation of molecular functionGO:00440922580.018
synaptic transmissionGO:00072683290.018
t cell proliferationGO:00420981200.018
negative regulation of immune effector processGO:0002698550.018
positive regulation of cell activationGO:00508671580.018
monocarboxylic acid metabolic processGO:00327871910.018
response to lipopolysaccharideGO:00324961280.018
cation transmembrane transportGO:00986552660.018
protein processingGO:00164851630.018
vesicle organizationGO:0016050600.018
lymphocyte differentiationGO:00300982420.018
inorganic cation transmembrane transportGO:00986622070.018
response to extracellular stimulusGO:00099911270.017
regulation of body fluid levelsGO:00508781620.017
dna metabolic processGO:00062593030.017
negative regulation of lymphocyte activationGO:0051250910.017
sequestering of calcium ionGO:0051208180.017
cellular divalent inorganic cation homeostasisGO:00725031270.017
positive regulation of kinase activityGO:00336741550.017
positive regulation of hydrolase activityGO:00513451480.017
muscle contractionGO:00069361010.017
respiratory system developmentGO:00605411900.017
guanosine containing compound catabolic processGO:19010691440.017
regulation of intracellular transportGO:00323861590.017
cellular response to biotic stimulusGO:0071216920.017
hormone secretionGO:00468791280.016
organic acid transportGO:00158491010.016
single organismal cell cell adhesionGO:00163371310.016
skin developmentGO:00435882200.016
carbohydrate homeostasisGO:00335001280.016
leukocyte mediated cytotoxicityGO:0001909620.016
regulation of homeostatic processGO:00328441820.016
exocytosisGO:00068871210.016
positive regulation of nervous system developmentGO:00519622210.016
regulation of vesicle mediated transportGO:00606271390.016
regulation of ossificationGO:00302781120.016
intracellular receptor signaling pathwayGO:0030522740.016
rho protein signal transductionGO:0007266320.015
negative regulation of phosphate metabolic processGO:00459361840.015
apoptotic signaling pathwayGO:00971903060.015
response to light stimulusGO:00094161350.015
regulation of response to woundingGO:19030341890.015
neuronal action potentialGO:0019228540.015
response to peptideGO:19016521360.015
multicellular organism growthGO:00352641610.015
organic acid biosynthetic processGO:0016053860.015
activation of innate immune responseGO:0002218560.015
regulation of protein transportGO:00512231630.015
protein modification by small protein conjugation or removalGO:00706472070.015
regulation of t cell proliferationGO:0042129920.015
chromatin modificationGO:00165681870.015
negative regulation of phosphorylationGO:00423261660.015
forebrain developmentGO:00309003020.015
maintenance of locationGO:0051235890.015
reactive nitrogen species metabolic processGO:200105700.015
positive regulation of protein phosphorylationGO:00019342420.015
protein localization to organelleGO:00333651850.015
compound eye developmentGO:004874910.015
cellular carbohydrate metabolic processGO:00442621190.014
immune response activating cell surface receptor signaling pathwayGO:0002429720.014
gtp catabolic processGO:00061841430.014
negative regulation of cytokine productionGO:0001818840.014
regulation of cell projection organizationGO:00313442060.014
angiogenesisGO:00015252010.014
nucleoside monophosphate metabolic processGO:0009123850.014
guanosine containing compound metabolic processGO:19010681440.014
regulation of nucleoside metabolic processGO:00091181300.014
organic hydroxy compound metabolic processGO:19016152030.014
positive regulation of cell developmentGO:00107202370.014
cognitionGO:00508901490.014
immune response regulating cell surface receptor signaling pathwayGO:0002768800.014
lymphocyte activation involved in immune responseGO:0002285930.014
regulation of nucleotide catabolic processGO:00308111220.014
cellular response to dna damage stimulusGO:00069742070.014
positive regulation of mapk cascadeGO:00434101700.014
intracellular protein transportGO:00068862040.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
circulatory system processGO:00030131970.014
inorganic ion transmembrane transportGO:00986602340.014
anatomical structure homeostasisGO:00602491450.014
regulation of muscle system processGO:0090257800.014
retrograde transport endosome to golgiGO:004214720.014
wound healingGO:00420601570.014
chromatin organizationGO:00063252060.014
blood vessel morphogenesisGO:00485142850.014
organophosphate biosynthetic processGO:00904071220.014
regulation of purine nucleotide catabolic processGO:00331211220.014
regulation of leukocyte differentiationGO:19021051590.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
methylationGO:00322591340.013
cellular response to hormone stimulusGO:00328701500.013
regulation of cell adhesionGO:00301551540.013
negative regulation of cellular amine metabolic processGO:003323910.013
negative regulation of mapk cascadeGO:0043409650.013
regulation of cell motilityGO:20001452360.013
sequestering of metal ionGO:0051238190.013
negative regulation of transferase activityGO:0051348850.013
phagocytosisGO:0006909660.013
organelle localizationGO:00516401790.013
positive regulation of transferase activityGO:00513471670.013
tissue homeostasisGO:00018941150.013
negative regulation of protein modification processGO:00314001630.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.013
positive regulation of nucleotide catabolic processGO:0030813880.013
extrinsic apoptotic signaling pathwayGO:00971911260.013
regulation of peptidase activityGO:0052547960.013
camera type eye developmentGO:00430102660.013
regulation of neuron differentiationGO:00456642810.013
divalent inorganic cation homeostasisGO:00725071380.013
stem cell differentiationGO:00488632680.013
organic hydroxy compound transportGO:0015850930.013
glial cell differentiationGO:00100011310.013
regulation of protein catabolic processGO:00421761080.013
hematopoietic progenitor cell differentiationGO:00022441430.013
cell growthGO:00160491300.013
glucose homeostasisGO:00425931280.013
lung developmentGO:00303241640.013
regulation of cellular response to stressGO:00801351590.013
positive regulation of lymphocyte activationGO:00512511400.013
positive regulation of cellular catabolic processGO:00313311480.013
respiratory tube developmentGO:00303231670.013
regulation of cytokine biosynthetic processGO:0042035590.013
positive regulation of t cell activationGO:00508701010.013
purinergic nucleotide receptor signaling pathwayGO:003559030.013
blood circulationGO:00080151950.013
mitochondrion organizationGO:00070051340.013
leukocyte homeostasisGO:0001776790.013
alcohol metabolic processGO:00060661160.013
t cell mediated immunityGO:0002456500.013
b cell activationGO:00421131610.013
cation homeostasisGO:00550802120.013
muscle tissue developmentGO:00605373080.013
tissue remodelingGO:00487711020.013
adult behaviorGO:00305341350.013
extracellular structure organizationGO:00430621480.013
negative regulation of growthGO:0045926990.013
peptidyl tyrosine phosphorylationGO:00181081430.012
regulation of interleukin 1 alpha productionGO:003265040.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
protein ubiquitinationGO:00165671710.012
hexose metabolic processGO:0019318980.012
negative regulation of hydrolase activityGO:0051346710.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
calcium ion homeostasisGO:00550741270.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
carboxylic acid biosynthetic processGO:0046394860.012
regulation of protein serine threonine kinase activityGO:00719001570.012
lymphocyte homeostasisGO:0002260640.012
cellular calcium ion homeostasisGO:00068741190.012
reactive oxygen species biosynthetic processGO:190340980.012
antigen receptor mediated signaling pathwayGO:0050851640.012
regulation of transmembrane transportGO:00347621280.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
nucleocytoplasmic transportGO:00069131390.012
nuclear divisionGO:00002801580.012
small molecule biosynthetic processGO:00442831320.012
lymphocyte apoptotic processGO:0070227540.012
negative regulation of t cell activationGO:0050868650.012
regulation of leukocyte mediated immunityGO:00027031040.012
regulation of protein complex assemblyGO:0043254830.012
nuclear transportGO:00511691390.012
regulation of cell cycleGO:00517262810.012
regulation of anatomical structure sizeGO:00900661780.012
single fertilizationGO:0007338820.012
interleukin 8 productionGO:003263740.012
divalent metal ion transportGO:00708381720.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
peptide hormone secretionGO:00300721090.012
atp metabolic processGO:0046034750.012
peptidyl tyrosine modificationGO:00182121450.011
cell substrate adhesionGO:00315891300.011
organelle fissionGO:00482851700.011
endocytosisGO:00068971680.011
negative regulation of kinase activityGO:0033673810.011
lipid transportGO:0006869980.011
connective tissue developmentGO:00614481790.011
sensory organ morphogenesisGO:00905962420.011
modification dependent protein catabolic processGO:00199411330.011
learning or memoryGO:00076111480.011
regulation of inflammatory responseGO:00507271470.011
meiotic cell cycleGO:00513211220.011
peptide transportGO:00158331330.011
extracellular matrix organizationGO:00301981470.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
brown fat cell differentiationGO:0050873360.011
urogenital system developmentGO:00016552610.011
microtubule based processGO:00070172360.011
response to nutrient levelsGO:00316671090.011
regulation of protein processingGO:0070613960.011
response to insulinGO:00328681000.011
protein localization to nucleusGO:00345041210.011
regulation of adaptive immune responseGO:0002819900.011
response to acid chemicalGO:00011011110.011
positive regulation of immune effector processGO:00026991070.011
engulfment of apoptotic cellGO:004365230.011
amide transportGO:00428861380.011
placenta developmentGO:00018901400.011
regulation of metal ion transportGO:00109591060.011
regulation of establishment of protein localizationGO:00702011810.011
gtp metabolic processGO:00460391440.011
protein oligomerizationGO:0051259670.011
regulation of ras protein signal transductionGO:00465781140.011
regulation of gtp catabolic processGO:00331241130.011
positive regulation of cell adhesionGO:0045785800.011
positive regulation of organelle organizationGO:00106381280.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
t cell extravasationGO:007268340.011
monocarboxylic acid biosynthetic processGO:0072330610.011
negative regulation of protein phosphorylationGO:00019331260.011
negative regulation of protein serine threonine kinase activityGO:0071901490.011
cellular response to growth factor stimulusGO:00713631970.011
innate immune response activating signal transductionGO:0002758500.011
actin cytoskeleton organizationGO:00300362200.011
monosaccharide metabolic processGO:00059961060.010
response to growth factorGO:00708481980.010
regulation of lymphocyte differentiationGO:00456191070.010
positive regulation of interferon alpha productionGO:003272740.010
dephosphorylationGO:00163111290.010
spermatid developmentGO:00072861080.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.010
regulation of cellular component biogenesisGO:00440871810.010
neuron deathGO:00709971540.010
mitotic cell cycle processGO:19030471590.010
bone remodelingGO:0046849530.010
renal system developmentGO:00720012250.010
relaxation of muscleGO:0090075180.010
smooth muscle contractionGO:0006939440.010
cellular response to extracellular stimulusGO:0031668810.010
regulation of leukocyte apoptotic processGO:2000106560.010
positive regulation of secretion by cellGO:19035321140.010
epithelial tube morphogenesisGO:00605623030.010
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.010
negative regulation of multi organism processGO:0043901680.010
pattern recognition receptor signaling pathwayGO:0002221470.010
cellular response to organic cyclic compoundGO:0071407870.010

Hpse disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
immune system diseaseDOID:291400.028
disease of metabolismDOID:001466700.024
nervous system diseaseDOID:86300.022
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.014
cancerDOID:16200.014
musculoskeletal system diseaseDOID:1700.013
connective tissue diseaseDOID:6500.012