Mus musculus

48 known processes

P2rx4

purinergic receptor P2X, ligand-gated ion channel 4

(Aliases: P2X4,D5Ertd444e,AW555605,AI504491)

P2rx4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.182
lymphocyte mediated immunityGO:00024491390.181
Mouse
positive regulation of t cell mediated cytotoxicityGO:0001916150.126
Mouse
lytic vacuole organizationGO:0080171210.120
Mouse
positive regulation of cytokine productionGO:00018191740.104
Mouse
adaptive immune responseGO:00022501550.104
Mouse
leukocyte mediated immunityGO:00024431740.100
Mouse
transmembrane transportGO:00550854120.099
cytokine productionGO:00018163190.097
Mouse
immune effector processGO:00022523210.090
Mouse
regulation of adaptive immune responseGO:0002819900.089
Mouse
carbohydrate derivative catabolic processGO:19011362310.078
reactive nitrogen species metabolic processGO:200105700.077
cation transportGO:00068123990.073
regulation of leukocyte mediated immunityGO:00027031040.069
Mouse
vacuole organizationGO:0007033380.067
Mouse
cellular ketone metabolic processGO:0042180840.065
cellular amine metabolic processGO:0044106440.064
t cell mediated immunityGO:0002456500.062
Mouse
sphingolipid metabolic processGO:0006665450.062
Mouse
positive regulation of apoptotic processGO:00430652170.062
Mouse
regulation of peptidase activityGO:0052547960.059
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.059
Mouse
divalent metal ion transportGO:00708381720.057
cation transmembrane transportGO:00986552660.054
regulation of lymphocyte mediated immunityGO:0002706840.053
Mouse
apoptotic signaling pathwayGO:00971903060.051
Human Mouse
organonitrogen compound catabolic processGO:19015652640.050
cellular amino acid metabolic processGO:00065201030.049
response to molecule of bacterial originGO:00022371430.049
Mouse
ceramide biosynthetic processGO:0046513200.048
Mouse
lysosome organizationGO:0007040210.048
Mouse
reactive oxygen species biosynthetic processGO:190340980.045
positive regulation of apoptotic signaling pathwayGO:2001235950.044
metal ion homeostasisGO:00550651890.044
Human Mouse
cation homeostasisGO:00550802120.044
Human Mouse
positive regulation of proteolysisGO:0045862850.044
Mouse
interleukin 1 beta productionGO:0032611300.043
Mouse
positive regulation of cell deathGO:00109422240.042
Mouse
regulation of membrane potentialGO:00423911920.042
regulation of cellular ketone metabolic processGO:0010565660.042
protein maturationGO:00516041760.042
Mouse
regulation of cellular amine metabolic processGO:0033238200.041
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.040
Mouse
regulation of establishment of protein localizationGO:00702011810.039
Mouse
regulation of cellular catabolic processGO:00313292420.039
nucleobase containing small molecule metabolic processGO:00550863520.039
cellular lipid metabolic processGO:00442553230.039
Mouse
phospholipid transfer to membraneGO:000664920.039
Mouse
nitrogen compound transportGO:00717052710.039
Mouse
multicellular organismal homeostasisGO:00488711640.039
Mouse
organophosphate catabolic processGO:00464342320.038
anion transportGO:00068201770.038
Mouse
regulation of t cell mediated immunityGO:0002709340.038
Mouse
amino acid transportGO:0006865610.038
Mouse
t cell activationGO:00421102890.038
Mouse
response to lipopolysaccharideGO:00324961280.037
Mouse
divalent inorganic cation transportGO:00725111780.037
protein processingGO:00164851630.036
Mouse
amine metabolic processGO:0009308450.036
homeostasis of number of cellsGO:00488722100.036
Mouse
glycosyl compound catabolic processGO:19016582060.036
regulation of cellular amino acid metabolic processGO:000652150.035
ossificationGO:00015032160.034
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342620.034
nucleoside phosphate metabolic processGO:00067533380.034
calcium ion transportGO:00068161590.033
alpha beta t cell activationGO:0046631910.032
sequestering of metal ionGO:0051238190.031
Mouse
cellular nitrogen compound catabolic processGO:00442702800.031
inorganic cation transmembrane transportGO:00986622070.031
endocytosisGO:00068971680.031
Mouse
ribonucleoside catabolic processGO:00424542060.030
nucleoside triphosphate metabolic processGO:00091412300.030
male gamete generationGO:00482322850.030
oxidation reduction processGO:00551143420.030
positive regulation of cellular amine metabolic processGO:003324050.029
carboxylic acid transportGO:00469421000.029
Mouse
regulation of secretionGO:00510462740.028
Mouse
negative regulation of cell activationGO:00508661110.028
carbohydrate metabolic processGO:00059752300.028
cell killingGO:0001906670.028
Mouse
skeletal system developmentGO:00015013560.027
Mouse
heterocycle catabolic processGO:00467002800.027
organic cyclic compound catabolic processGO:19013612950.027
interleukin 1 productionGO:0032612310.027
Mouse
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.027
Mouse
positive regulation of reactive oxygen species biosynthetic processGO:190342820.027
sphingolipid catabolic processGO:003014970.027
nucleoside catabolic processGO:00091642060.027
macromolecule catabolic processGO:00090572810.027
Mouse
cell activation involved in immune responseGO:00022631260.026
positive regulation of peptidase activityGO:0010952490.026
Mouse
purine ribonucleoside catabolic processGO:00461302050.026
regulation of apoptotic signaling pathwayGO:20012331970.026
leukocyte apoptotic processGO:0071887710.026
Mouse
cellular chemical homeostasisGO:00550822150.026
Human Mouse
regulation of interferon gamma productionGO:0032649570.025
glycosyl compound metabolic processGO:19016572460.025
regulation of protein localizationGO:00328802310.025
Mouse
cellular macromolecule catabolic processGO:00442652060.025
regulation of cytokine productionGO:00018172660.025
Mouse
maintenance of locationGO:0051235890.025
Mouse
leukocyte differentiationGO:00025213420.025
defense response to bacteriumGO:00427421190.025
Mouse
regulation of defense responseGO:00313472330.025
purine ribonucleoside metabolic processGO:00461282410.025
ceramide metabolic processGO:0006672310.024
Mouse
organic anion transportGO:00157111370.024
Mouse
aromatic compound catabolic processGO:00194392860.024
cellular metal ion homeostasisGO:00068751510.024
Human Mouse
response to extracellular stimulusGO:00099911270.024
Mouse
organic acid transportGO:00158491010.024
Mouse
regulation of secretion by cellGO:19035302490.024
Mouse
nucleotide metabolic processGO:00091173320.024
antigen processing and presentation of exogenous antigenGO:0019884260.024
ribonucleotide metabolic processGO:00092592910.024
interleukin 1 secretionGO:0050701160.023
Mouse
transition metal ion transportGO:0000041380.023
response to endoplasmic reticulum stressGO:0034976530.023
glycoprotein metabolic processGO:00091001160.023
negative regulation of lymphocyte proliferationGO:0050672450.023
cellular homeostasisGO:00197252400.023
Human Mouse
regulation of body fluid levelsGO:00508781620.022
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.022
regulation of lymphocyte proliferationGO:00506701170.022
multicellular organismal signalingGO:0035637910.022
neuronal action potentialGO:0019228540.022
divalent inorganic cation homeostasisGO:00725071380.022
Human Mouse
negative regulation of cytokine productionGO:0001818840.022
leukocyte activation involved in immune responseGO:00023661260.022
regulation of cell activationGO:00508652890.022
cellular response to lipidGO:00713961450.022
nucleoside metabolic processGO:00091162460.022
positive regulation of defense responseGO:00313491240.022
positive regulation of immune effector processGO:00026991070.021
Mouse
regulation of protein secretionGO:0050708820.021
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
positive regulation of programmed cell deathGO:00430682180.021
Mouse
regulation of bindingGO:00510981110.021
regulation of t cell activationGO:00508631700.021
anatomical structure homeostasisGO:00602491450.021
Mouse
regulation of leukocyte mediated cytotoxicityGO:0001910380.021
Mouse
interleukin 8 productionGO:003263740.021
cellular divalent inorganic cation homeostasisGO:00725031270.021
Human Mouse
antigen processing and presentationGO:0019882470.021
production of molecular mediator of immune responseGO:00024401030.021
regulation of hydrolase activityGO:00513362460.021
Mouse
cellular ion homeostasisGO:00068731650.021
Human Mouse
cellular protein catabolic processGO:00442571550.020
peptidyl amino acid modificationGO:00181933360.020
calcium ion transmembrane transportGO:0070588850.020
antigen processing and presentation of endogenous peptide antigen via mhc class ibGO:000247640.020
vesicle organizationGO:0016050600.020
Mouse
cytoplasmic transportGO:00164822340.020
Human Mouse
leukocyte mediated cytotoxicityGO:0001909620.019
Mouse
inorganic ion transmembrane transportGO:00986602340.019
negative regulation of t cell activationGO:0050868650.019
neurotransmitter transportGO:0006836760.019
Mouse
interferon gamma productionGO:0032609670.019
peptidyl tyrosine modificationGO:00182121450.019
positive regulation of protein phosphorylationGO:00019342420.019
Mouse
muscle system processGO:00030121410.019
Human Mouse
cellular response to molecule of bacterial originGO:0071219830.019
tissue homeostasisGO:00018941150.019
Mouse
reactive oxygen species metabolic processGO:0072593840.018
Mouse
membrane lipid metabolic processGO:0006643530.018
Mouse
cellular response to cytokine stimulusGO:00713451890.018
lipid transportGO:0006869980.018
Mouse
nucleoside phosphate catabolic processGO:19012922220.018
regulation of reactive oxygen species metabolic processGO:2000377400.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
t cell mediated cytotoxicityGO:0001913260.018
Mouse
regulation of leukocyte apoptotic processGO:2000106560.018
Mouse
negative regulation of cellular component organizationGO:00511291940.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.018
positive regulation of interleukin 1 beta productionGO:0032731160.018
Mouse
organonitrogen compound biosynthetic processGO:19015661920.018
Mouse
nucleoside triphosphate catabolic processGO:00091432050.018
negative regulation of cell proliferationGO:00082852960.018
response to organic cyclic compoundGO:00140701980.018
Human Mouse
purine nucleoside triphosphate metabolic processGO:00091442260.018
cytokine secretionGO:0050663720.018
Mouse
cell recognitionGO:0008037830.017
glucose homeostasisGO:00425931280.017
positive regulation of secretion by cellGO:19035321140.017
Mouse
peptidyl tyrosine phosphorylationGO:00181081430.017
regulation of homeostatic processGO:00328441820.017
Human Mouse
purine nucleoside triphosphate catabolic processGO:00091462030.017
regulation of endopeptidase activityGO:0052548890.017
Mouse
purine nucleotide catabolic processGO:00061952110.017
multi multicellular organism processGO:00447061090.017
Mouse
epithelial cell proliferationGO:00506731740.017
angiogenesisGO:00015252010.017
ribonucleotide catabolic processGO:00092612080.017
intrinsic apoptotic signaling pathwayGO:00971931320.017
regulation of cellular response to stressGO:00801351590.017
cellular response to lipopolysaccharideGO:0071222770.017
positive regulation of interferon gamma productionGO:0032729390.017
regulation of inflammatory responseGO:00507271470.017
glial cell apoptotic processGO:003434930.016
locomotory behaviorGO:00076261950.016
regulation of system processGO:00440572000.016
Human Mouse
positive regulation of macroautophagyGO:001623930.016
t cell differentiationGO:00302171740.016
macromolecule glycosylationGO:0043413550.016
neuron deathGO:00709971540.016
positive regulation of lymphocyte mediated immunityGO:0002708620.016
Mouse
cytokine biosynthetic processGO:0042089680.016
purine containing compound catabolic processGO:00725232130.016
nucleotide catabolic processGO:00091662170.015
purine ribonucleotide catabolic processGO:00091542080.015
wound healingGO:00420601570.015
Mouse
regulation of lymphocyte activationGO:00512492400.015
positive regulation of secretionGO:00510471300.015
Mouse
endomembrane system organizationGO:00102561470.015
Mouse
synaptic transmissionGO:00072683290.015
ribonucleoside triphosphate catabolic processGO:00092031990.015
carbohydrate derivative biosynthetic processGO:19011371830.015
extracellular structure organizationGO:00430621480.015
negative regulation of cellular protein metabolic processGO:00322692470.015
atp metabolic processGO:0046034750.015
action potentialGO:0001508780.015
ribose phosphate metabolic processGO:00196932910.015
purine nucleoside catabolic processGO:00061522050.015
regulation of postsynaptic membrane potentialGO:0060078480.015
ribonucleoside metabolic processGO:00091192450.015
spermatogenesisGO:00072832840.015
transition metal ion homeostasisGO:0055076540.015
positive regulation of protein modification processGO:00314012990.015
Mouse
negative regulation of response to woundingGO:1903035770.015
response to inorganic substanceGO:0010035960.015
Mouse
biomineral tissue developmentGO:0031214640.015
Mouse
regulation of neuron deathGO:19012141340.015
positive regulation of interleukin 1 alpha productionGO:003273040.015
Mouse
regulation of neuron apoptotic processGO:00435231220.015
antigen processing and presentation of peptide antigenGO:0048002290.015
regulation of response to woundingGO:19030341890.014
negative regulation of t cell proliferationGO:0042130380.014
positive regulation of transferase activityGO:00513471670.014
Mouse
extracellular matrix organizationGO:00301981470.014
calcium ion homeostasisGO:00550741270.014
Human Mouse
iron ion import into cellGO:009745940.014
lipid localizationGO:00108761260.014
Mouse
membrane lipid biosynthetic processGO:0046467320.014
Mouse
negative regulation of protein metabolic processGO:00512482820.014
lung developmentGO:00303241640.014
fertilizationGO:00095661270.014
purine ribonucleotide metabolic processGO:00091502900.014
cell adhesionGO:00071553290.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
cellular response to extracellular stimulusGO:0031668810.014
Mouse
inflammatory responseGO:00069542440.014
Mouse
negative regulation of nervous system developmentGO:00519611560.014
purine nucleotide metabolic processGO:00061633020.014
interleukin 6 productionGO:0032635580.014
Mouse
lymphocyte activation involved in immune responseGO:0002285930.014
regulation of cell cycleGO:00517262810.014
positive regulation of cell activationGO:00508671580.013
cytosolic calcium ion homeostasisGO:0051480700.013
Human Mouse
immune response regulating signaling pathwayGO:00027641250.013
regulation of kinase activityGO:00435492490.013
Mouse
purine nucleoside metabolic processGO:00422782410.013
membrane organizationGO:00610242450.013
Mouse
nitric oxide metabolic processGO:0046209250.013
anion transmembrane transportGO:0098656710.013
interleukin 1 beta secretionGO:0050702160.013
Mouse
immunoglobulin mediated immune responseGO:0016064690.013
positive regulation of innate immune responseGO:0045089800.013
myelinationGO:0042552740.013
neurotransmitter secretionGO:0007269620.013
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.013
negative regulation of defense responseGO:0031348770.013
regulation of ossificationGO:00302781120.013
Mouse
regulation of cytokine secretionGO:0050707610.013
Mouse
negative regulation of immune effector processGO:0002698550.013
positive regulation of protein secretionGO:0050714520.013
Mouse
glycosphingolipid catabolic processGO:004647950.013
protein oligomerizationGO:0051259670.013
Mouse
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988530.013
regulation of proteolysisGO:00301621640.013
Mouse
negative regulation of hypersensitivityGO:000288430.013
purine nucleoside monophosphate catabolic processGO:0009128580.013
organelle assemblyGO:00709251770.013
Mouse
innate immune responseGO:00450871570.013
macroautophagyGO:0016236210.013
learning or memoryGO:00076111480.013
lateral inhibitionGO:004633110.013
lymphocyte proliferationGO:00466511640.012
Mouse
regulation of cytoskeleton organizationGO:00514931220.012
blood vessel morphogenesisGO:00485142850.012
sequestering of calcium ionGO:0051208180.012
Mouse
dicarboxylic acid transportGO:0006835290.012
Mouse
response to acid chemicalGO:00011011110.012
positive regulation of hydrolase activityGO:00513451480.012
Mouse
nitric oxide biosynthetic processGO:0006809250.012
small molecule catabolic processGO:0044282710.012
muscle contractionGO:00069361010.012
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
establishment of vesicle localizationGO:0051650810.012
Mouse
exocytosisGO:00068871210.012
Mouse
negative regulation of molecular functionGO:00440922580.012
regulation of neuron differentiationGO:00456642810.012
regulation of vesicle mediated transportGO:00606271390.012
phospholipid transportGO:0015914210.012
Mouse
neuron apoptotic processGO:00514021420.012
organic hydroxy compound metabolic processGO:19016152030.012
cytokine production involved in immune responseGO:0002367340.012
detection of stimulusGO:0051606840.012
Mouse
negative regulation of lymphocyte activationGO:0051250910.012
negative regulation of phosphorus metabolic processGO:00105631840.012
Mouse
gtp metabolic processGO:00460391440.012
lipid catabolic processGO:0016042690.012
regulation of protein transportGO:00512231630.012
Mouse
protein secretionGO:00093061110.012
Mouse
leukocyte proliferationGO:00706611720.012
Mouse
negative regulation of leukocyte proliferationGO:0070664460.012
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.012
engulfment of apoptotic cellGO:004365230.012
establishment of synaptic vesicle localizationGO:0097480570.012
Mouse
cellular calcium ion homeostasisGO:00068741190.012
Human Mouse
neuromuscular processGO:0050905990.012
regulation of neurotransmitter levelsGO:0001505870.012
Mouse
sterol transportGO:0015918380.012
coagulationGO:0050817780.012
Mouse
regulation of protein maturationGO:1903317960.012
regulation of interleukin 1 beta productionGO:0032651250.012
Mouse
defense response to other organismGO:00985421970.012
Mouse
viral processGO:0016032410.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.012
Mouse
nucleoside monophosphate metabolic processGO:0009123850.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.011
developmental maturationGO:00217001930.011
organelle membrane fusionGO:009017410.011
regulation of interleukin 8 productionGO:003267730.011
lymphocyte apoptotic processGO:0070227540.011
Mouse
epidermis developmentGO:00085441870.011
regulation of t cell mediated cytotoxicityGO:0001914180.011
Mouse
skin developmentGO:00435882200.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
response to starvationGO:0042594650.011
interleukin 2 productionGO:0032623330.011
respiratory system developmentGO:00605411900.011
adult behaviorGO:00305341350.011
regulation of protein serine threonine kinase activityGO:00719001570.011
Mouse
negative regulation of proteolysisGO:0045861740.011
regulation of mapk cascadeGO:00434082480.011
Mouse
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
negative regulation of immune system processGO:00026832090.011
positive regulation of protein transportGO:0051222930.011
Mouse
ear developmentGO:00435832000.011
cytokine metabolic processGO:0042107710.011
acute inflammatory responseGO:0002526410.011
regulation of interleukin 1 productionGO:0032652260.011
Mouse
negative regulation of phosphate metabolic processGO:00459361840.011
Mouse
immune response inhibiting signal transductionGO:000276540.011
phagolysosome assemblyGO:000184530.011
Mouse
adult locomotory behaviorGO:0008344910.011
negative regulation of interleukin 8 productionGO:003271710.010
multicellular organismal metabolic processGO:0044236280.010
Mouse
cognitionGO:00508901490.010
regulation of leukocyte proliferationGO:00706631210.010
dephosphorylationGO:00163111290.010
synaptic vesicle localizationGO:0097479590.010
Mouse
positive regulation of t cell mediated immunityGO:0002711240.010
Mouse
response to topologically incorrect proteinGO:0035966250.010
oligosaccharide catabolic processGO:000931320.010
glucosamine containing compound metabolic processGO:190107130.010
antigen processing and presentation of exogenous peptide antigenGO:0002478210.010
atp catabolic processGO:0006200550.010
regulation of t cell proliferationGO:0042129920.010
regulation of acute inflammatory responseGO:0002673270.010
cellular amide metabolic processGO:0043603580.010
negative regulation of cellular amine metabolic processGO:003323910.010
monosaccharide metabolic processGO:00059961060.010
icosanoid secretionGO:0032309120.010
Mouse

P2rx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.596
inherited metabolic disorderDOID:65500.596
nervous system diseaseDOID:86300.160
disease of anatomical entityDOID:700.160
central nervous system diseaseDOID:33100.096
sensory system diseaseDOID:005015500.031
eye and adnexa diseaseDOID:149200.022
retinal diseaseDOID:567900.021
eye diseaseDOID:561400.021
lysosomal storage diseaseDOID:321100.019
lipid storage diseaseDOID:945500.018
immune system diseaseDOID:291400.018
cerebral degenerationDOID:144300.015
brain diseaseDOID:93600.015
retinal degenerationDOID:846600.014
neuropathyDOID:87000.013
connective tissue diseaseDOID:6500.013
musculoskeletal system diseaseDOID:1700.013
disease of mental healthDOID:15000.013
sphingolipidosisDOID:192700.012
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
acquired metabolic diseaseDOID:006015800.012
vascular diseaseDOID:17800.010
cardiovascular system diseaseDOID:128700.010
bone diseaseDOID:008000100.010