Mus musculus

19 known processes

Hps5

Hermansky-Pudlak syndrome 5 homolog (human)

(Aliases: hz,C85120,MGC99886,maroon,AI646796,haze,mr,ru2,AL022647,ru-2)

Hps5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pigment accumulationGO:004347611.000
establishment of melanosome localizationGO:0032401110.993
pigment granule localizationGO:0051875130.967
melanosome transportGO:0032402110.925
melanosome localizationGO:0032400120.922
coagulationGO:0050817780.902
melanosome organizationGO:003243880.853
anterograde synaptic vesicle transportGO:0048490150.844
anterograde axon cargo transportGO:0008089200.826
microtubule based transportGO:0010970500.825
blood coagulationGO:0007596760.790
microtubule based movementGO:0007018840.773
hemostasisGO:0007599780.766
pigment granule transportGO:0051904120.731
regulation of natural killer cell activationGO:0032814220.712
vesicle localizationGO:0051648860.687
cytoskeleton dependent intracellular transportGO:0030705500.679
pigment cell differentiationGO:0050931270.629
pigmentationGO:0043473710.627
cellular pigmentationGO:0033059200.583
secretion of lysosomal enzymesGO:003329960.555
melanocyte differentiationGO:0030318250.550
regulation of body fluid levelsGO:00508781620.525
developmental pigmentationGO:0048066400.492
Zebrafish
synaptic vesicle localizationGO:0097479590.436
secretory granule organizationGO:0033363200.400
establishment of vesicle localizationGO:0051650810.383
establishment of organelle localizationGO:00516561220.353
axon cargo transportGO:0008088330.345
natural killer cell degranulationGO:004332030.329
pigment granule organizationGO:004875390.316
natural killer cell activationGO:0030101440.312
organelle localizationGO:00516401790.304
synaptic transmissionGO:00072683290.303
lytic vacuole organizationGO:0080171210.284
positive regulation of natural killer cell activationGO:0032816150.283
vesicle organizationGO:0016050600.273
positive regulation of lymphocyte activationGO:00512511400.272
wound healingGO:00420601570.268
natural killer cell activation involved in immune responseGO:0002323100.245
establishment of synaptic vesicle localizationGO:0097480570.220
regulation of pigment cell differentiationGO:005093270.181
establishment of pigment granule localizationGO:0051905120.175
microtubule based processGO:00070172360.174
regulation of lymphocyte activationGO:00512492400.165
synaptic vesicle transportGO:0048489570.153
endomembrane system organizationGO:00102561470.148
neuroepithelial cell differentiationGO:0060563370.146
positive regulation of cell activationGO:00508671580.144
organophosphate catabolic processGO:00464342320.142
regulation of cell activationGO:00508652890.121
cellular nitrogen compound catabolic processGO:00442702800.120
nucleoside phosphate catabolic processGO:19012922220.092
purine ribonucleoside triphosphate metabolic processGO:00092052200.090
regulation of reactive oxygen species biosynthetic processGO:190342620.088
columnar cuboidal epithelial cell differentiationGO:0002065820.084
lysosome organizationGO:0007040210.083
nucleoside phosphate metabolic processGO:00067533380.082
nucleotide metabolic processGO:00091173320.081
purine nucleoside metabolic processGO:00422782410.076
purine nucleotide metabolic processGO:00061633020.073
antigen processing and presentation of lipid antigen via mhc class ibGO:004800330.072
positive regulation of reactive oxygen species biosynthetic processGO:190342820.071
nucleoside catabolic processGO:00091642060.070
purine containing compound metabolic processGO:00725213110.068
leukocyte differentiationGO:00025213420.067
transmembrane transportGO:00550854120.067
exosomal secretionGO:199018210.066
purine nucleoside triphosphate metabolic processGO:00091442260.065
nucleoside triphosphate metabolic processGO:00091412300.062
nucleobase containing small molecule metabolic processGO:00550863520.061
ribose phosphate metabolic processGO:00196932910.061
purine nucleoside triphosphate catabolic processGO:00091462030.059
ribonucleoside metabolic processGO:00091192450.059
cytoplasmic transportGO:00164822340.057
purine ribonucleoside triphosphate catabolic processGO:00092071990.057
organonitrogen compound catabolic processGO:19015652640.055
organic cyclic compound catabolic processGO:19013612950.054
ribonucleoside catabolic processGO:00424542060.054
nucleoside metabolic processGO:00091162460.054
cellular lipid metabolic processGO:00442553230.054
eye pigmentationGO:004806930.053
Zebrafish
ribonucleotide metabolic processGO:00092592910.053
regulation of cellular catabolic processGO:00313292420.052
purine ribonucleotide metabolic processGO:00091502900.051
regulation of lymphocyte differentiationGO:00456191070.051
purine nucleotide catabolic processGO:00061952110.051
camera type eye developmentGO:00430102660.049
glycosyl compound metabolic processGO:19016572460.049
aromatic compound catabolic processGO:00194392860.048
purine nucleoside catabolic processGO:00061522050.045
cytotoxic t cell degranulationGO:004331620.044
heterocycle catabolic processGO:00467002800.044
protein targetingGO:00066051430.044
cellular protein catabolic processGO:00442571550.043
purine ribonucleoside catabolic processGO:00461302050.043
gtp metabolic processGO:00460391440.043
neuromuscular processGO:0050905990.043
nucleoside triphosphate catabolic processGO:00091432050.043
glycosyl compound catabolic processGO:19016582060.042
cation transmembrane transportGO:00986552660.042
lymphocyte mediated immunityGO:00024491390.041
protein targeting to vacuoleGO:000662330.041
nitrogen compound transportGO:00717052710.040
vacuole organizationGO:0007033380.039
nucleotide catabolic processGO:00091662170.039
reactive oxygen species biosynthetic processGO:190340980.038
ribonucleotide catabolic processGO:00092612080.038
immune effector processGO:00022523210.038
purine ribonucleotide catabolic processGO:00091542080.038
purine ribonucleoside metabolic processGO:00461282410.038
t cell differentiationGO:00302171740.038
regulation of reactive oxygen species metabolic processGO:2000377400.038
ribonucleoside triphosphate metabolic processGO:00091992200.038
carbohydrate derivative catabolic processGO:19011362310.037
ribonucleoside triphosphate catabolic processGO:00092031990.036
macromolecule catabolic processGO:00090572810.035
inorganic ion transmembrane transportGO:00986602340.035
membrane organizationGO:00610242450.035
reactive oxygen species metabolic processGO:0072593840.034
lipid homeostasisGO:0055088630.034
establishment of protein localization to vacuoleGO:007266640.033
lipid localizationGO:00108761260.033
regulation of endocytosisGO:0030100690.032
protein localization to vacuoleGO:007266540.032
intracellular protein transportGO:00068862040.031
defense response to bacteriumGO:00427421190.031
natural killer cell mediated cytotoxicityGO:0042267290.030
protein secretionGO:00093061110.030
t cell activationGO:00421102890.029
positive regulation of cellular catabolic processGO:00313311480.028
positive regulation of pigment cell differentiationGO:005094250.028
regulation of protein catabolic processGO:00421761080.028
protein catabolic processGO:00301632210.028
purine containing compound catabolic processGO:00725232130.028
establishment of protein localization to organelleGO:00725941180.028
positive regulation of phagocytosisGO:0050766260.027
neuromuscular process controlling balanceGO:0050885590.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
positive regulation of reactive oxygen species metabolic processGO:2000379110.026
cellular homeostasisGO:00197252400.026
cellular macromolecule catabolic processGO:00442652060.026
regulation of cellular ketone metabolic processGO:0010565660.026
inorganic cation transmembrane transportGO:00986622070.025
positive regulation of cellular protein catabolic processGO:1903364340.025
regulation of purine nucleotide metabolic processGO:19005421690.025
cell adhesionGO:00071553290.025
adaptive immune responseGO:00022501550.025
cation transportGO:00068123990.024
positive regulation of leukocyte differentiationGO:1902107860.024
amine metabolic processGO:0009308450.024
early endosome to late endosome transportGO:004502220.024
regulation of nucleotide metabolic processGO:00061401690.024
cellular amine metabolic processGO:0044106440.024
apoptotic signaling pathwayGO:00971903060.023
cellular amino acid metabolic processGO:00065201030.023
regulation of ion transportGO:00432692150.023
positive regulation of cellular amine metabolic processGO:003324050.023
carbohydrate derivative biosynthetic processGO:19011371830.022
regulation of cellular amino acid metabolic processGO:000652150.022
regulation of leukocyte differentiationGO:19021051590.022
phospholipid metabolic processGO:0006644870.022
gtp catabolic processGO:00061841430.021
embryonic organ morphogenesisGO:00485622760.021
protein targeting to lysosomeGO:000662220.021
ear morphogenesisGO:00424711180.021
carbohydrate metabolic processGO:00059752300.021
endosome organizationGO:000703290.021
ear developmentGO:00435832000.021
regulation of cellular protein catabolic processGO:1903362610.021
leukocyte mediated cytotoxicityGO:0001909620.020
regulation of hydrolase activityGO:00513362460.020
ion transmembrane transportGO:00342203610.020
monocarboxylic acid metabolic processGO:00327871910.020
positive regulation of purine nucleotide metabolic processGO:19005441140.019
antigen processing and presentationGO:0019882470.019
positive regulation of protein catabolic processGO:0045732600.019
natural killer cell mediated immunityGO:0002228290.019
sensory organ morphogenesisGO:00905962420.019
guanosine containing compound catabolic processGO:19010691440.019
organic hydroxy compound metabolic processGO:19016152030.019
lymphocyte differentiationGO:00300982420.018
cation homeostasisGO:00550802120.018
neurotransmitter transportGO:0006836760.018
retina development in camera type eyeGO:00600411190.018
phagocytosisGO:0006909660.018
cell activation involved in immune responseGO:00022631260.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.018
endocytosisGO:00068971680.018
membrane fusionGO:0061025380.018
organonitrogen compound biosynthetic processGO:19015661920.017
protein maturationGO:00516041760.017
cellular ketone metabolic processGO:0042180840.017
regulation of alpha beta t cell activationGO:0046634530.017
cellular ion homeostasisGO:00068731650.017
platelet activationGO:0030168400.017
g protein coupled receptor signaling pathwayGO:00071862430.017
maintenance of locationGO:0051235890.016
glucose homeostasisGO:00425931280.016
interleukin 8 productionGO:003263740.016
lipid biosynthetic processGO:00086101790.016
regulation of cellular amine metabolic processGO:0033238200.016
innate immune responseGO:00450871570.016
regulation of t cell activationGO:00508631700.016
protein localization to organelleGO:00333651850.016
leukocyte mediated immunityGO:00024431740.016
guanosine containing compound metabolic processGO:19010681440.015
cell killingGO:0001906670.015
chromatin modificationGO:00165681870.015
small gtpase mediated signal transductionGO:0007264970.015
urogenital system developmentGO:00016552610.015
myeloid cell differentiationGO:00300992330.015
compound eye developmentGO:004874910.015
peptidyl amino acid modificationGO:00181933360.014
regulation of phagocytosisGO:0050764330.014
alpha beta t cell differentiationGO:0046632690.014
lymphocyte activation involved in immune responseGO:0002285930.014
regulation of nucleotide catabolic processGO:00308111220.014
oxidation reduction processGO:00551143420.014
positive regulation of hydrolase activityGO:00513451480.014
platelet aggregationGO:0070527200.014
divalent metal ion transportGO:00708381720.014
protein processingGO:00164851630.014
regulation of t cell differentiationGO:0045580830.014
actin cytoskeleton organizationGO:00300362200.014
muscle tissue developmentGO:00605373080.014
regulation of interleukin 8 productionGO:003267730.013
cellular chemical homeostasisGO:00550822150.013
cellular carbohydrate metabolic processGO:00442621190.013
pigment metabolic processGO:0042440320.013
positive regulation of endocytosisGO:0045807420.013
regulation of organelle organizationGO:00330432890.013
glycoprotein metabolic processGO:00091001160.013
cytokine productionGO:00018163190.012
adult behaviorGO:00305341350.012
anion transportGO:00068201770.012
positive regulation of nucleoside metabolic processGO:0045979910.012
organelle assemblyGO:00709251770.012
cell type specific apoptotic processGO:00972852680.012
negative regulation of cellular component organizationGO:00511291940.012
hematopoietic progenitor cell differentiationGO:00022441430.012
alpha amino acid metabolic processGO:1901605590.012
development of primary sexual characteristicsGO:00451371430.012
male gamete generationGO:00482322850.012
regulation of nucleoside metabolic processGO:00091181300.012
neuronal action potentialGO:0019228540.012
glycoprotein biosynthetic processGO:0009101890.012
neurotransmitter secretionGO:0007269620.012
organophosphate biosynthetic processGO:00904071220.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
single organismal cell cell adhesionGO:00163371310.012
protein modification by small protein conjugationGO:00324461870.011
regulation of proteolysisGO:00301621640.011
negative regulation of intracellular signal transductionGO:19025321670.011
positive regulation of lymphocyte differentiationGO:0045621610.011
cellular protein complex assemblyGO:00436231160.011
protein ubiquitinationGO:00165671710.011
protein modification by small protein conjugation or removalGO:00706472070.011
rna interferenceGO:001624620.011
t cell mediated immunityGO:0002456500.011
response to extracellular stimulusGO:00099911270.011
dephosphorylationGO:00163111290.011
organic anion transportGO:00157111370.011
renal system developmentGO:00720012250.011
leukocyte activation involved in immune responseGO:00023661260.011
asymmetric stem cell divisionGO:009872230.011
positive regulation of t cell differentiationGO:0045582520.011
wnt signaling pathwayGO:00160551880.011
regulation of secretion by cellGO:19035302490.011
posttranscriptional regulation of gene expressionGO:00106081550.011
homotypic cell cell adhesionGO:0034109280.011
positive regulation of secretionGO:00510471300.011
carboxylic acid biosynthetic processGO:0046394860.011
negative regulation of protein metabolic processGO:00512482820.011
tissue remodelingGO:00487711020.011
calcium ion dependent exocytosisGO:0017156350.011
hormone secretionGO:00468791280.011
organic acid biosynthetic processGO:0016053860.011
small molecule biosynthetic processGO:00442831320.010
negative regulation of cell developmentGO:00107211690.010
gonad developmentGO:00084061410.010
positive regulation of programmed cell deathGO:00430682180.010
sulfur compound biosynthetic processGO:0044272370.010
positive regulation of interferon alpha productionGO:003272740.010
positive regulation of protein modification processGO:00314012990.010
ossificationGO:00015032160.010
myeloid leukocyte mediated immunityGO:0002444420.010
glycerolipid metabolic processGO:00464861220.010
regulation of exocytosisGO:0017157610.010
positive regulation of developmental pigmentationGO:004808760.010
regulation of gtp catabolic processGO:00331241130.010
negative regulation of cellular protein metabolic processGO:00322692470.010
positive regulation of secretion by cellGO:19035321140.010

Hps5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.032
disease of anatomical entityDOID:700.032
immune system diseaseDOID:291400.025
musculoskeletal system diseaseDOID:1700.014
inherited metabolic disorderDOID:65500.014
disease of metabolismDOID:001466700.014
connective tissue diseaseDOID:6500.013
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
bone diseaseDOID:008000100.011