Mus musculus

33 known processes

Hps4

Hermansky-Pudlak syndrome 4 homolog (human)

(Aliases: BLOC-3,le,mKIAA1667,AU040608,C130020P05Rik,2010205O06Rik)

Hps4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pigment accumulationGO:004347611.000
microtubule based movementGO:0007018840.874
microtubule based transportGO:0010970500.694
pigment cell differentiationGO:0050931270.635
anterograde synaptic vesicle transportGO:0048490150.613
developmental pigmentationGO:0048066400.603
anterograde axon cargo transportGO:0008089200.532
antigen processing and presentation of lipid antigen via mhc class ibGO:004800330.461
axon cargo transportGO:0008088330.447
cytoskeleton dependent intracellular transportGO:0030705500.446
synaptic vesicle localizationGO:0097479590.407
vesicle localizationGO:0051648860.389
synaptic transmissionGO:00072683290.380
pigmentationGO:0043473710.362
microtubule based processGO:00070172360.361
antigen processing and presentation exogenous lipid antigen via mhc class ibGO:004800730.350
antigen processing and presentation via mhc class ibGO:000247580.305
melanosome organizationGO:003243880.272
synaptic vesicle transportGO:0048489570.271
protein localization to organelleGO:00333651850.267
gene silencing by rnaGO:0031047190.256
establishment of organelle localizationGO:00516561220.251
vesicle organizationGO:0016050600.235
regulation of cell activationGO:00508652890.234
establishment of synaptic vesicle localizationGO:0097480570.228
positive regulation of lymphocyte activationGO:00512511400.227
eye pigmentationGO:004806930.225
regulation of lymphocyte activationGO:00512492400.215
positive regulation of cell activationGO:00508671580.209
synaptic vesicle membrane organizationGO:004849910.207
lymphocyte differentiationGO:00300982420.199
pigment granule organizationGO:004875390.199
establishment of melanosome localizationGO:0032401110.179
organelle localizationGO:00516401790.177
lysosome organizationGO:0007040210.174
regulation of t cell activationGO:00508631700.168
establishment of vesicle localizationGO:0051650810.168
secretion of lysosomal enzymesGO:003329960.167
regulation of alpha beta t cell differentiationGO:0046637350.159
regulation of natural killer cell activationGO:0032814220.157
positive regulation of alpha beta t cell activationGO:0046635390.155
melanosome transportGO:0032402110.144
pigment granule localizationGO:0051875130.125
regulation of alpha beta t cell activationGO:0046634530.112
positive regulation of alpha beta t cell differentiationGO:0046638280.111
zinc ion homeostasisGO:0055069100.111
cellular zinc ion homeostasisGO:000688290.103
regulation of lymphocyte differentiationGO:00456191070.102
cellular pigmentationGO:0033059200.101
pigment biosynthetic processGO:0046148260.099
nk t cell differentiationGO:000186580.091
antigen processing and presentationGO:0019882470.089
alpha beta t cell differentiationGO:0046632690.088
antigen processing and presentation of exogenous antigenGO:0019884260.086
cation homeostasisGO:00550802120.086
cellular ion homeostasisGO:00068731650.082
secondary metabolite biosynthetic processGO:0044550110.078
lytic vacuole organizationGO:0080171210.078
maintenance of locationGO:0051235890.078
positive regulation of lymphocyte differentiationGO:0045621610.074
positive regulation of leukocyte differentiationGO:1902107860.073
transition metal ion homeostasisGO:0055076540.070
alpha beta t cell activationGO:0046631910.066
regulation of t cell differentiationGO:0045580830.065
negative regulation of gene silencingGO:006096920.064
metal ion homeostasisGO:00550651890.063
secretory granule organizationGO:0033363200.063
intracellular protein transportGO:00068862040.062
endocytosisGO:00068971680.062
cellular transition metal ion homeostasisGO:0046916320.062
cytoplasmic transportGO:00164822340.060
t cell activationGO:00421102890.060
cellular homeostasisGO:00197252400.055
cellular chemical homeostasisGO:00550822150.055
leukocyte differentiationGO:00025213420.055
modification dependent macromolecule catabolic processGO:00436321330.054
positive regulation of t cell activationGO:00508701010.054
vacuole organizationGO:0007033380.053
establishment of protein localization to vacuoleGO:007266640.051
positive regulation of t cell differentiationGO:0045582520.050
protein targetingGO:00066051430.049
gene silencingGO:0016458380.048
pigment granule transportGO:0051904120.047
regulation of ion homeostasisGO:2000021640.046
membrane organizationGO:00610242450.045
developmental maturationGO:00217001930.045
sequestering of metal ionGO:0051238190.045
endomembrane system organizationGO:00102561470.044
cellular macromolecule catabolic processGO:00442652060.043
positive regulation of natural killer cell activationGO:0032816150.042
regulation of leukocyte differentiationGO:19021051590.042
camera type eye developmentGO:00430102660.042
exocytosisGO:00068871210.042
cellular nitrogen compound catabolic processGO:00442702800.042
nucleotide metabolic processGO:00091173320.041
body morphogenesisGO:0010171450.039
dna repairGO:00062811070.039
ear developmentGO:00435832000.038
nucleobase containing small molecule metabolic processGO:00550863520.037
protein targeting to vacuoleGO:000662330.036
cellular metal ion homeostasisGO:00068751510.036
embryonic organ morphogenesisGO:00485622760.035
dna metabolic processGO:00062593030.035
regulation of transcription from rna polymerase iii promoterGO:000635920.034
macromolecule catabolic processGO:00090572810.034
cellular protein catabolic processGO:00442571550.033
regulation of homeostatic processGO:00328441820.032
ear morphogenesisGO:00424711180.032
t cell differentiationGO:00302171740.032
cell divisionGO:00513011200.032
protein localization to vacuoleGO:007266540.031
mitotic cytokinesisGO:000028140.031
nitrogen compound transportGO:00717052710.031
sensory organ morphogenesisGO:00905962420.030
chromatin modificationGO:00165681870.030
small gtpase mediated signal transductionGO:0007264970.030
immune effector processGO:00022523210.030
negative regulation of protein metabolic processGO:00512482820.030
pigment metabolic processGO:0042440320.029
purine nucleotide metabolic processGO:00061633020.028
regulation of cellular catabolic processGO:00313292420.028
amine metabolic processGO:0009308450.028
protein secretionGO:00093061110.028
establishment of protein localization to organelleGO:00725941180.028
nucleoside phosphate catabolic processGO:19012922220.028
secondary metabolic processGO:0019748180.027
coagulationGO:0050817780.027
carbohydrate derivative biosynthetic processGO:19011371830.027
regulation of body fluid levelsGO:00508781620.026
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.026
negative regulation of gene silencing by rnaGO:006096710.026
purine nucleoside triphosphate metabolic processGO:00091442260.026
heterocycle catabolic processGO:00467002800.026
melanosome localizationGO:0032400120.026
glycosyl compound catabolic processGO:19016582060.025
ribonucleoside catabolic processGO:00424542060.025
transmembrane transportGO:00550854120.025
retina development in camera type eyeGO:00600411190.025
proteasomal protein catabolic processGO:0010498980.024
cellular divalent inorganic cation homeostasisGO:00725031270.024
gpi anchor metabolic processGO:000650570.023
cellular response to dna damage stimulusGO:00069742070.023
regulation of cellular amino acid metabolic processGO:000652150.023
ribonucleotide metabolic processGO:00092592910.022
protein catabolic processGO:00301632210.022
nucleoside catabolic processGO:00091642060.022
positive regulation of cellular amine metabolic processGO:003324050.022
protein modification by small protein conjugationGO:00324461870.022
positive regulation of protein catabolic processGO:0045732600.022
purine nucleoside metabolic processGO:00422782410.021
regulation of organelle organizationGO:00330432890.021
regulation of proteolysisGO:00301621640.020
inclusion body assemblyGO:007084130.020
regulation of mitotic cell cycleGO:00073461260.020
neuronal action potentialGO:0019228540.020
innate immune responseGO:00450871570.020
regulation of cytoskeleton organizationGO:00514931220.020
regulation of cellular ketone metabolic processGO:0010565660.019
male gamete generationGO:00482322850.019
cytokine productionGO:00018163190.019
regulation of protein catabolic processGO:00421761080.019
cell adhesionGO:00071553290.019
protein modification by small protein conjugation or removalGO:00706472070.019
spermatogenesisGO:00072832840.019
aromatic compound catabolic processGO:00194392860.019
ribose phosphate metabolic processGO:00196932910.019
lymphocyte mediated immunityGO:00024491390.019
cilium morphogenesisGO:00602711020.019
protein targeting to lysosomeGO:000662220.018
protein localization to membraneGO:00726571080.018
neuromuscular processGO:0050905990.018
notch receptor processingGO:000722040.018
nucleoside triphosphate catabolic processGO:00091432050.018
phospholipid metabolic processGO:0006644870.018
organic cyclic compound catabolic processGO:19013612950.018
actin cytoskeleton organizationGO:00300362200.018
fertilizationGO:00095661270.018
protein localization to nucleusGO:00345041210.018
cellular ketone metabolic processGO:0042180840.018
cellular amine metabolic processGO:0044106440.017
posttranscriptional regulation of gene expressionGO:00106081550.017
lipid localizationGO:00108761260.017
modification dependent protein catabolic processGO:00199411330.017
interleukin 8 productionGO:003263740.017
purine nucleotide catabolic processGO:00061952110.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
negative regulation of cellular component organizationGO:00511291940.017
cellular lipid metabolic processGO:00442553230.017
regulation of reactive oxygen species biosynthetic processGO:190342620.017
reactive oxygen species metabolic processGO:0072593840.016
cell type specific apoptotic processGO:00972852680.016
reactive oxygen species biosynthetic processGO:190340980.016
heart morphogenesisGO:00030071780.016
epithelial tube formationGO:00721751300.016
homeostasis of number of cellsGO:00488722100.016
protein processingGO:00164851630.016
nucleoside metabolic processGO:00091162460.015
multicellular organismal signalingGO:0035637910.015
natural killer cell activationGO:0030101440.015
nucleoside phosphate metabolic processGO:00067533380.015
carbohydrate metabolic processGO:00059752300.015
mitotic cell cycle processGO:19030471590.015
positive regulation of bindingGO:0051099490.015
negative regulation of cellular protein metabolic processGO:00322692470.015
appendage developmentGO:00487361660.015
telencephalon developmentGO:00215371860.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
wound healingGO:00420601570.014
regulation of mapk cascadeGO:00434082480.014
positive regulation of programmed cell deathGO:00430682180.014
regulation of actin nucleationGO:005112540.014
organophosphate catabolic processGO:00464342320.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.014
regulation of hydrolase activityGO:00513362460.014
purine containing compound catabolic processGO:00725232130.014
digestive tract developmentGO:00485651900.014
pallium developmentGO:00215431200.014
regulation of cellular amine metabolic processGO:0033238200.014
adaptive immune responseGO:00022501550.014
single fertilizationGO:0007338820.014
cation transmembrane transportGO:00986552660.014
purine containing compound metabolic processGO:00725213110.014
response to acid chemicalGO:00011011110.014
viral gene expressionGO:001908030.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
purine ribonucleotide catabolic processGO:00091542080.014
mapk cascadeGO:00001652810.014
dna replicationGO:0006260520.014
negative regulation of immune system processGO:00026832090.014
protein maturationGO:00516041760.014
activation of immune responseGO:00022531380.014
regulation of membrane potentialGO:00423911920.013
positive regulation of actin nucleationGO:005112730.013
negative regulation of intracellular signal transductionGO:19025321670.013
ribonucleoside metabolic processGO:00091192450.013
lipid storageGO:0019915360.013
b cell activationGO:00421131610.013
positive regulation of proteolysisGO:0045862850.013
ribonucleotide catabolic processGO:00092612080.013
organelle assemblyGO:00709251770.013
regulation of cytokine productionGO:00018172660.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
cell activation involved in immune responseGO:00022631260.013
inorganic ion transmembrane transportGO:00986602340.013
rna processingGO:00063961050.013
tube closureGO:0060606910.013
transcription from rna polymerase iii promoterGO:000638330.013
nucleoside triphosphate metabolic processGO:00091412300.013
regulation of bindingGO:00510981110.012
adult behaviorGO:00305341350.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
regulation of interleukin 8 productionGO:003267730.012
action potentialGO:0001508780.012
inorganic cation transmembrane transportGO:00986622070.012
immune response regulating signaling pathwayGO:00027641250.012
peptidyl amino acid modificationGO:00181933360.012
regulation of cell motilityGO:20001452360.012
purine nucleoside catabolic processGO:00061522050.012
defense response to bacteriumGO:00427421190.012
muscle tissue developmentGO:00605373080.012
negative regulation of viral transcriptionGO:003289730.012
negative regulation of phosphorus metabolic processGO:00105631840.012
urogenital system developmentGO:00016552610.012
production of molecular mediator of immune responseGO:00024401030.012
neural tube closureGO:0001843900.012
regulation of cell cycleGO:00517262810.012
oocyte constructionGO:000730820.012
primary neural tube formationGO:0014020950.012
neuroepithelial cell differentiationGO:0060563370.012
positive regulation of interleukin 8 productionGO:003275720.012
apoptotic signaling pathwayGO:00971903060.012
regulation of cellular response to stressGO:00801351590.012
compound eye developmentGO:004874910.012
spermatid differentiationGO:00485151150.012
anatomical structure homeostasisGO:00602491450.012
hemostasisGO:0007599780.012
negative regulation of phosphate metabolic processGO:00459361840.012
positive regulation of mapk cascadeGO:00434101700.012
purine ribonucleoside metabolic processGO:00461282410.012
response to light stimulusGO:00094161350.012
germ cell developmentGO:00072811850.011
morphogenesis of embryonic epitheliumGO:00163311590.011
nucleoside monophosphate metabolic processGO:0009123850.011
positive regulation of nucleoside metabolic processGO:0045979910.011
transmission of nerve impulseGO:0019226760.011
histone deubiquitinationGO:001657820.011
nucleotide catabolic processGO:00091662170.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
negative regulation of cell developmentGO:00107211690.011
organophosphate biosynthetic processGO:00904071220.011
forebrain developmentGO:00309003020.011
peptidyl tyrosine phosphorylationGO:00181081430.011
segmentationGO:0035282930.011
symbiosis encompassing mutualism through parasitismGO:0044403830.011
norepinephrine transportGO:001587420.011
cellular protein complex assemblyGO:00436231160.011
skeletal system developmentGO:00015013560.011
glycosyl compound metabolic processGO:19016572460.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
male meiosis iGO:0007141160.011
defense response to other organismGO:00985421970.011
cellular response to acid chemicalGO:0071229680.011
negative regulation of cell cycleGO:00457861230.010
telomere maintenance in response to dna damageGO:004324740.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.010
cellular response to transforming growth factor beta stimulusGO:0071560880.010
cellular amino acid metabolic processGO:00065201030.010
regulation of protein complex assemblyGO:0043254830.010
tube formationGO:00351481400.010
lipid homeostasisGO:0055088630.010
cilium assemblyGO:0042384810.010
membrane lipid metabolic processGO:0006643530.010
sequestering of calcium ionGO:0051208180.010
purine ribonucleotide metabolic processGO:00091502900.010
neural tube formationGO:00018411080.010
oxidation reduction processGO:00551143420.010
regulation of defense responseGO:00313472330.010
carbohydrate derivative catabolic processGO:19011362310.010
chromosome segregationGO:0007059480.010
phospholipid biosynthetic processGO:0008654360.010
response to retinoic acidGO:0032526560.010
hematopoietic progenitor cell differentiationGO:00022441430.010
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.010
mrna metabolic processGO:0016071840.010
regulation of nlrp3 inflammasome complex assemblyGO:190022540.010

Hps4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.038
central nervous system diseaseDOID:33100.016
neuropathyDOID:87000.014
neurodegenerative diseaseDOID:128900.011
sensory system diseaseDOID:005015500.010