Mus musculus

33 known processes

Hps6

Hermansky-Pudlak syndrome 6

(Aliases: 5330434M19Rik,ru,MGC31055,BLOC2)

Hps6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pigment accumulationGO:004347610.989
pigmentationGO:0043473710.942
establishment of melanosome localizationGO:0032401110.926
melanosome organizationGO:003243880.845
coagulationGO:0050817780.833
pigment granule localizationGO:0051875130.832
melanocyte differentiationGO:0030318250.807
hemostasisGO:0007599780.783
anterograde axon cargo transportGO:0008089200.782
microtubule based transportGO:0010970500.774
microtubule based movementGO:0007018840.749
pigment cell differentiationGO:0050931270.721
regulation of natural killer cell activationGO:0032814220.699
melanosome transportGO:0032402110.628
regulation of body fluid levelsGO:00508781620.538
melanosome localizationGO:0032400120.534
secretion of lysosomal enzymesGO:003329960.503
wound healingGO:00420601570.455
secretory granule organizationGO:0033363200.403
anterograde synaptic vesicle transportGO:0048490150.383
vesicle organizationGO:0016050600.355
vesicle localizationGO:0051648860.355
cellular pigmentationGO:0033059200.335
pigment granule transportGO:0051904120.319
blood coagulationGO:0007596760.301
neuroepithelial cell differentiationGO:0060563370.300
pigment granule organizationGO:004875390.296
synaptic vesicle transportGO:0048489570.240
cytoskeleton dependent intracellular transportGO:0030705500.228
developmental pigmentationGO:0048066400.224
establishment of organelle localizationGO:00516561220.218
natural killer cell activationGO:0030101440.201
pigment biosynthetic processGO:0046148260.153
axon cargo transportGO:0008088330.142
positive regulation of natural killer cell activationGO:0032816150.123
regulation of lymphocyte activationGO:00512492400.121
regulation of pigment cell differentiationGO:005093270.113
regulation of cell activationGO:00508652890.108
establishment of vesicle localizationGO:0051650810.103
lytic vacuole organizationGO:0080171210.102
positive regulation of cell activationGO:00508671580.094
establishment of synaptic vesicle localizationGO:0097480570.091
organelle localizationGO:00516401790.088
lysosome organizationGO:0007040210.084
eye pigmentationGO:004806930.078
synaptic vesicle localizationGO:0097479590.078
microtubule based processGO:00070172360.072
natural killer cell degranulationGO:004332030.069
positive regulation of lymphocyte activationGO:00512511400.066
regulation of reactive oxygen species biosynthetic processGO:190342620.054
synaptic transmissionGO:00072683290.051
nucleoside metabolic processGO:00091162460.050
cellular amino acid metabolic processGO:00065201030.048
columnar cuboidal epithelial cell differentiationGO:0002065820.048
protein targetingGO:00066051430.047
establishment of pigment granule localizationGO:0051905120.047
natural killer cell activation involved in immune responseGO:0002323100.046
camera type eye developmentGO:00430102660.044
aromatic compound catabolic processGO:00194392860.042
positive regulation of reactive oxygen species biosynthetic processGO:190342820.042
protein targeting to vacuoleGO:000662330.041
retina development in camera type eyeGO:00600411190.040
vacuole organizationGO:0007033380.039
nucleotide metabolic processGO:00091173320.038
protein secretionGO:00093061110.036
pigment metabolic processGO:0042440320.035
ketone body metabolic processGO:190222430.035
leukocyte differentiationGO:00025213420.035
cytoplasmic transportGO:00164822340.034
purine ribonucleoside metabolic processGO:00461282410.034
alpha amino acid metabolic processGO:1901605590.034
heterocycle catabolic processGO:00467002800.033
carbohydrate derivative catabolic processGO:19011362310.033
nucleotide catabolic processGO:00091662170.032
regulation of cellular amino acid metabolic processGO:000652150.032
reactive oxygen species biosynthetic processGO:190340980.031
ribonucleoside triphosphate catabolic processGO:00092031990.030
regulation of leukocyte differentiationGO:19021051590.030
purine nucleoside triphosphate metabolic processGO:00091442260.029
adaptive immune responseGO:00022501550.029
neuromuscular process controlling balanceGO:0050885590.029
negative regulation of protein metabolic processGO:00512482820.029
small gtpase mediated signal transductionGO:0007264970.029
cell adhesionGO:00071553290.029
organic cyclic compound catabolic processGO:19013612950.027
regulation of organelle organizationGO:00330432890.027
t cell activationGO:00421102890.027
purine containing compound metabolic processGO:00725213110.027
glycosyl compound metabolic processGO:19016572460.026
nucleoside catabolic processGO:00091642060.026
purine ribonucleoside catabolic processGO:00461302050.026
organic hydroxy compound transportGO:0015850930.025
amine metabolic processGO:0009308450.025
immune effector processGO:00022523210.025
cation transportGO:00068123990.025
cellular amine metabolic processGO:0044106440.024
organonitrogen compound catabolic processGO:19015652640.024
nucleobase containing small molecule metabolic processGO:00550863520.024
lymphocyte mediated immunityGO:00024491390.024
purine nucleotide catabolic processGO:00061952110.023
lipid localizationGO:00108761260.023
purine containing compound catabolic processGO:00725232130.023
protein localization to vacuoleGO:007266540.023
cellular nitrogen compound catabolic processGO:00442702800.023
regulation of reactive oxygen species metabolic processGO:2000377400.023
purine nucleoside catabolic processGO:00061522050.022
t cell differentiationGO:00302171740.022
antigen processing and presentation exogenous lipid antigen via mhc class ibGO:004800730.022
response to lipopolysaccharideGO:00324961280.022
regulation of secretion by cellGO:19035302490.022
nucleoside phosphate catabolic processGO:19012922220.022
negative regulation of phosphate metabolic processGO:00459361840.022
glycosyl compound catabolic processGO:19016582060.022
establishment of protein localization to organelleGO:00725941180.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
stem cell proliferationGO:00720891170.021
purine ribonucleotide catabolic processGO:00091542080.021
lymphocyte differentiationGO:00300982420.021
apoptotic signaling pathwayGO:00971903060.021
regulation of cellular ketone metabolic processGO:0010565660.021
guanosine containing compound catabolic processGO:19010691440.021
transmembrane transportGO:00550854120.021
antigen processing and presentation of lipid antigen via mhc class ibGO:004800330.021
nucleoside triphosphate catabolic processGO:00091432050.021
purine ribonucleotide metabolic processGO:00091502900.021
positive regulation of cell developmentGO:00107202370.021
cation transmembrane transportGO:00986552660.021
placenta developmentGO:00018901400.020
nucleoside phosphate metabolic processGO:00067533380.020
ribonucleotide metabolic processGO:00092592910.020
cell killingGO:0001906670.020
glycoprotein metabolic processGO:00091001160.020
cell activation involved in immune responseGO:00022631260.020
intracellular protein transportGO:00068862040.020
cellular lipid metabolic processGO:00442553230.019
compound eye developmentGO:004874910.019
fatty acid metabolic processGO:00066311210.019
positive regulation of pigment cell differentiationGO:005094250.019
regulation of hydrolase activityGO:00513362460.019
cellular ketone metabolic processGO:0042180840.018
inorganic cation transmembrane transportGO:00986622070.018
establishment of protein localization to vacuoleGO:007266640.018
endomembrane system organizationGO:00102561470.018
regulation of lymphocyte differentiationGO:00456191070.018
regulation of protein transportGO:00512231630.018
dna metabolic processGO:00062593030.018
positive regulation of reactive oxygen species metabolic processGO:2000379110.018
defense response to bacteriumGO:00427421190.018
guanosine containing compound metabolic processGO:19010681440.018
negative regulation of cellular protein metabolic processGO:00322692470.018
purine nucleoside metabolic processGO:00422782410.017
regulation of ion transportGO:00432692150.017
monocarboxylic acid metabolic processGO:00327871910.017
regulation of cellular amine metabolic processGO:0033238200.017
ribonucleotide catabolic processGO:00092612080.017
actin cytoskeleton organizationGO:00300362200.017
regulation of cellular catabolic processGO:00313292420.017
negative regulation of phosphorus metabolic processGO:00105631840.017
organic hydroxy compound metabolic processGO:19016152030.017
cellular homeostasisGO:00197252400.017
cellular macromolecule catabolic processGO:00442652060.017
regulation of endocytosisGO:0030100690.017
nitrogen compound transportGO:00717052710.017
positive regulation of cellular amine metabolic processGO:003324050.016
cytokine productionGO:00018163190.016
regulation of secretionGO:00510462740.016
neuromuscular processGO:0050905990.016
lipid homeostasisGO:0055088630.016
purine nucleotide metabolic processGO:00061633020.016
inorganic ion transmembrane transportGO:00986602340.016
positive regulation of nervous system developmentGO:00519622210.016
negative regulation of cellular amino acid metabolic processGO:004576300.016
sensory organ morphogenesisGO:00905962420.016
positive regulation of cellular amino acid metabolic processGO:004576430.016
organonitrogen compound biosynthetic processGO:19015661920.016
gtp catabolic processGO:00061841430.016
ribonucleoside catabolic processGO:00424542060.016
cell type specific apoptotic processGO:00972852680.016
negative regulation of cellular amine metabolic processGO:003323910.016
g protein coupled receptor signaling pathwayGO:00071862430.016
antigen processing and presentationGO:0019882470.015
myeloid cell differentiationGO:00300992330.015
oxidation reduction processGO:00551143420.015
carbohydrate derivative biosynthetic processGO:19011371830.015
reactive oxygen species metabolic processGO:0072593840.015
cation homeostasisGO:00550802120.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
alpha beta t cell differentiationGO:0046632690.015
regulation of defense responseGO:00313472330.014
protein maturationGO:00516041760.014
response to molecule of bacterial originGO:00022371430.014
positive regulation of protein modification processGO:00314012990.014
regulation of nucleotide metabolic processGO:00061401690.014
protein processingGO:00164851630.014
ribonucleoside metabolic processGO:00091192450.014
membrane organizationGO:00610242450.014
positive regulation of nucleoside metabolic processGO:0045979910.013
cellular ion homeostasisGO:00068731650.013
defense response to other organismGO:00985421970.013
regulation of inflammatory responseGO:00507271470.013
neuronal action potentialGO:0019228540.013
regulation of t cell activationGO:00508631700.013
organophosphate catabolic processGO:00464342320.013
ossificationGO:00015032160.013
regulation of t cell differentiationGO:0045580830.013
protein catabolic processGO:00301632210.013
embryonic organ morphogenesisGO:00485622760.013
cell divisionGO:00513011200.013
negative regulation of intracellular signal transductionGO:19025321670.013
chromatin modificationGO:00165681870.013
ras protein signal transductionGO:0007265770.013
positive regulation of secretion by cellGO:19035321140.013
maintenance of locationGO:0051235890.013
regulation of protein localizationGO:00328802310.013
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433640.013
spermatogenesisGO:00072832840.013
positive regulation of lymphocyte differentiationGO:0045621610.013
regulation of neurotransmitter transportGO:0051588350.012
thymus developmentGO:0048538410.012
cellular protein catabolic processGO:00442571550.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
negative regulation of cellular component organizationGO:00511291940.012
alpha beta t cell activationGO:0046631910.012
response to inorganic substanceGO:0010035960.012
ear developmentGO:00435832000.012
negative regulation of phosphorylationGO:00423261660.012
leukocyte activation involved in immune responseGO:00023661260.012
regulation of transferase activityGO:00513382630.012
positive regulation of secretionGO:00510471300.012
regulation of anatomical structure sizeGO:00900661780.012
negative regulation of molecular functionGO:00440922580.012
carbohydrate metabolic processGO:00059752300.012
regulation of interleukin 8 productionGO:003267730.012
gtp metabolic processGO:00460391440.012
positive regulation of cellular catabolic processGO:00313311480.012
single organismal cell cell adhesionGO:00163371310.012
small molecule biosynthetic processGO:00442831320.012
interleukin 8 productionGO:003263740.012
adult behaviorGO:00305341350.012
tyrosine metabolic processGO:000657040.012
innate immune responseGO:00450871570.012
mapk cascadeGO:00001652810.012
regulation of response to woundingGO:19030341890.012
glycoprotein biosynthetic processGO:0009101890.011
ribose phosphate metabolic processGO:00196932910.011
forebrain developmentGO:00309003020.011
cellular response to lipopolysaccharideGO:0071222770.011
early endosome to late endosome transportGO:004502220.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
male gamete generationGO:00482322850.011
nucleoside triphosphate metabolic processGO:00091412300.011
tissue remodelingGO:00487711020.011
negative regulation of cell activationGO:00508661110.011
organophosphate biosynthetic processGO:00904071220.011
muscle system processGO:00030121410.011
regulation of proteolysisGO:00301621640.011
regulation of kinase activityGO:00435492490.011
regulation of apoptotic signaling pathwayGO:20012331970.011
regulation of cysteine type endopeptidase activityGO:2000116650.011
natural killer cell mediated cytotoxicityGO:0042267290.011
protein localization to organelleGO:00333651850.011
regulation of establishment of protein localizationGO:00702011810.011
negative regulation of cell cycleGO:00457861230.011
cytotoxic t cell degranulationGO:004331620.011
positive regulation of nucleotide catabolic processGO:0030813880.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
multicellular organismal signalingGO:0035637910.011
cellular response to organonitrogen compoundGO:00714171450.011
negative regulation of cell developmentGO:00107211690.010
positive regulation of hydrolase activityGO:00513451480.010
rna interferenceGO:001624620.010
response to organonitrogen compoundGO:00102432460.010
germ cell developmentGO:00072811850.010
cellular response to lipidGO:00713961450.010
lymphocyte activation involved in immune responseGO:0002285930.010
positive regulation of nucleotide metabolic processGO:00459811140.010
heart morphogenesisGO:00030071780.010
organic hydroxy compound biosynthetic processGO:1901617770.010
lateral inhibitionGO:004633110.010
positive regulation of gtpase activityGO:0043547850.010
anion transportGO:00068201770.010
protein targeting to lysosomeGO:000662220.010

Hps6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.033
disease of anatomical entityDOID:700.033
immune system diseaseDOID:291400.021
sensory system diseaseDOID:005015500.016
eye diseaseDOID:561400.014
eye and adnexa diseaseDOID:149200.014
disease of metabolismDOID:001466700.013
musculoskeletal system diseaseDOID:1700.012
connective tissue diseaseDOID:6500.010
bone diseaseDOID:008000100.010
neuromuscular diseaseDOID:44000.010
neuropathyDOID:87000.010