Mus musculus

76 known processes

Hps1

Hermansky-Pudlak syndrome 1 homolog (human)

(Aliases: Hps,MGC102063,BB405864,6030422N11Rik,ep)

Hps1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pigment accumulationGO:004347610.999
pigment granule localizationGO:0051875130.997
coagulationGO:0050817780.997
pigmentationGO:0043473710.996
establishment of melanosome localizationGO:0032401110.996
melanocyte differentiationGO:0030318250.996
melanosome organizationGO:003243880.994
pigment cell differentiationGO:0050931270.992
hemostasisGO:0007599780.980
developmental pigmentationGO:0048066400.977
secretory granule organizationGO:0033363200.971
lytic vacuole organizationGO:0080171210.971
lysosome organizationGO:0007040210.966
cellular pigmentationGO:0033059200.960
neuroepithelial cell differentiationGO:0060563370.959
blood coagulationGO:0007596760.958
melanosome transportGO:0032402110.936
pigment granule organizationGO:004875390.923
pigment granule transportGO:0051904120.916
vesicle organizationGO:0016050600.895
melanosome localizationGO:0032400120.865
establishment of vesicle localizationGO:0051650810.861
vesicle localizationGO:0051648860.856
microtubule based movementGO:0007018840.791
regulation of body fluid levelsGO:00508781620.716
vacuole organizationGO:0007033380.697
microtubule based transportGO:0010970500.659
cytoskeleton dependent intracellular transportGO:0030705500.652
anterograde axon cargo transportGO:0008089200.567
establishment of organelle localizationGO:00516561220.536
secretion of lysosomal enzymesGO:003329960.514
antigen processing and presentation of lipid antigen via mhc class ibGO:004800330.512
establishment of synaptic vesicle localizationGO:0097480570.444
establishment of pigment granule localizationGO:0051905120.330
wound healingGO:00420601570.321
pigment biosynthetic processGO:0046148260.317
phenol containing compound biosynthetic processGO:0046189210.313
cytoplasmic transportGO:00164822340.267
organelle localizationGO:00516401790.257
regulation of pigment cell differentiationGO:005093270.239
anterograde synaptic vesicle transportGO:0048490150.231
pigment metabolic processGO:0042440320.201
columnar cuboidal epithelial cell differentiationGO:0002065820.162
positive regulation of secretion by cellGO:19035321140.155
cellular ion homeostasisGO:00068731650.131
natural killer cell degranulationGO:004332030.129
synaptic vesicle transportGO:0048489570.114
neutrophil mediated immunityGO:0002446190.106
regulation of cell activationGO:00508652890.104
organic hydroxy compound metabolic processGO:19016152030.102
natural killer cell activation involved in immune responseGO:0002323100.099
cation homeostasisGO:00550802120.090
cellular homeostasisGO:00197252400.088
organic hydroxy compound biosynthetic processGO:1901617770.086
short chain fatty acid metabolic processGO:004645960.086
defense response to bacteriumGO:00427421190.082
leukocyte differentiationGO:00025213420.082
regulation of secretion by cellGO:19035302490.076
phagosome maturationGO:009038240.075
fatty acid metabolic processGO:00066311210.074
leukocyte mediated immunityGO:00024431740.072
defense response to gram positive bacteriumGO:0050830500.071
synaptic vesicle localizationGO:0097479590.070
immune effector processGO:00022523210.069
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.066
protein targetingGO:00066051430.065
axon cargo transportGO:0008088330.063
interspecies interaction between organismsGO:0044419830.062
reactive oxygen species biosynthetic processGO:190340980.062
regulation of lymphocyte activationGO:00512492400.059
nucleoside metabolic processGO:00091162460.058
microtubule based processGO:00070172360.057
protein secretionGO:00093061110.056
protein localization to vacuoleGO:007266540.055
positive regulation of cell activationGO:00508671580.055
innate immune responseGO:00450871570.054
protein targeting to vacuoleGO:000662330.053
regulation of reactive oxygen species biosynthetic processGO:190342620.053
melanin metabolic processGO:0006582120.053
phagocytosisGO:0006909660.051
phospholipid transfer to membraneGO:000664920.051
positive regulation of lymphocyte activationGO:00512511400.048
platelet aggregationGO:0070527200.048
adaptive immune responseGO:00022501550.047
cation transmembrane transportGO:00986552660.047
cell chemotaxisGO:0060326810.047
cellular lipid metabolic processGO:00442553230.047
positive regulation of nervous system developmentGO:00519622210.046
secondary metabolic processGO:0019748180.044
protein modification by small protein conjugation or removalGO:00706472070.044
cellular chemical homeostasisGO:00550822150.044
positive regulation of exocytosisGO:0045921200.043
fertilizationGO:00095661270.043
alpha beta t cell differentiationGO:0046632690.043
nucleotide metabolic processGO:00091173320.043
lipid localizationGO:00108761260.042
macromolecule catabolic processGO:00090572810.042
purine nucleoside triphosphate metabolic processGO:00091442260.042
establishment of protein localization to vacuoleGO:007266640.041
production of molecular mediator of immune responseGO:00024401030.041
membrane organizationGO:00610242450.040
lipid homeostasisGO:0055088630.040
nucleobase containing small molecule metabolic processGO:00550863520.040
b cell activationGO:00421131610.040
response to inorganic substanceGO:0010035960.040
natural killer cell activationGO:0030101440.040
defense response to other organismGO:00985421970.039
negative regulation of immune system processGO:00026832090.039
cell killingGO:0001906670.038
alpha amino acid metabolic processGO:1901605590.038
regulation of endocytosisGO:0030100690.037
synaptic transmissionGO:00072683290.036
melanin biosynthetic processGO:0042438100.035
reactive oxygen species metabolic processGO:0072593840.035
actin cytoskeleton organizationGO:00300362200.035
cell proliferation in forebrainGO:0021846300.034
regulation of intracellular phGO:0051453110.034
alpha beta t cell activationGO:0046631910.034
skeletal system morphogenesisGO:00487052030.034
secondary metabolite biosynthetic processGO:0044550110.033
lymphocyte differentiationGO:00300982420.033
response to transforming growth factor betaGO:0071559880.032
regulation of ion transportGO:00432692150.032
cell activation involved in immune responseGO:00022631260.032
cell type specific apoptotic processGO:00972852680.031
phospholipid metabolic processGO:0006644870.031
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.031
positive regulation of reactive oxygen species biosynthetic processGO:190342820.031
body morphogenesisGO:0010171450.031
regulation of developmental pigmentationGO:0048070140.030
platelet activationGO:0030168400.030
dna metabolic processGO:00062593030.029
spermatogenesisGO:00072832840.028
transmembrane transportGO:00550854120.028
ribonucleotide metabolic processGO:00092592910.028
organic cyclic compound catabolic processGO:19013612950.028
lymphocyte mediated immunityGO:00024491390.028
regulation of secretionGO:00510462740.028
positive regulation of secretionGO:00510471300.027
regulation of vascular smooth muscle contractionGO:000305610.027
mesodermal cell migrationGO:000807840.027
regulation of interleukin 8 productionGO:003267730.027
regulation of cell adhesionGO:00301551540.027
cellular macromolecule catabolic processGO:00442652060.027
endomembrane system organizationGO:00102561470.027
cellular response to dna damage stimulusGO:00069742070.027
nitrogen compound transportGO:00717052710.027
ketone body metabolic processGO:190222430.027
cell adhesionGO:00071553290.027
immune response regulating signaling pathwayGO:00027641250.027
lipid storageGO:0019915360.027
lymphocyte homeostasisGO:0002260640.026
neuromuscular processGO:0050905990.026
interleukin 8 productionGO:003263740.026
regulation of cellular phGO:0030641120.025
cytokine productionGO:00018163190.025
ion transmembrane transportGO:00342203610.025
embryonic skeletal system developmentGO:00487061200.025
protein catabolic processGO:00301632210.025
calcium ion homeostasisGO:00550741270.024
multicellular organismal homeostasisGO:00488711640.024
cofactor transportGO:005118140.024
purine containing compound metabolic processGO:00725213110.024
trachea cartilage morphogenesisGO:006053540.024
male gamete generationGO:00482322850.023
aromatic compound catabolic processGO:00194392860.023
defense response to protozoanGO:0042832250.023
regulation of phGO:0006885260.022
leukocyte migrationGO:00509001240.022
dna repairGO:00062811070.022
stem cell developmentGO:00488642190.022
positive regulation of reactive oxygen species metabolic processGO:2000379110.022
nucleoside phosphate metabolic processGO:00067533380.022
regulation of asymmetric cell divisionGO:000978640.022
defecationGO:003042110.021
ectodermal cell differentiationGO:001066830.021
cholesterol metabolic processGO:0008203560.021
regulation of organelle organizationGO:00330432890.021
cellular response to acid chemicalGO:0071229680.021
compound eye developmentGO:004874910.020
regulation of reactive oxygen species metabolic processGO:2000377400.020
cellular protein catabolic processGO:00442571550.020
purine nucleoside catabolic processGO:00061522050.020
cellular response to oxidative stressGO:0034599760.020
extrinsic apoptotic signaling pathwayGO:00971911260.020
homeostasis of number of cellsGO:00488722100.020
divalent inorganic cation homeostasisGO:00725071380.020
regulation of interleukin 6 productionGO:0032675550.020
regulation of cytoskeleton organizationGO:00514931220.020
genetic imprintingGO:0071514270.020
regulation of cellular response to stressGO:00801351590.019
skeletal system developmentGO:00015013560.019
purine nucleotide metabolic processGO:00061633020.019
regulation of lymphocyte differentiationGO:00456191070.019
inorganic cation transmembrane transportGO:00986622070.019
gastrulationGO:00073691160.019
chromatin modificationGO:00165681870.019
spinal cord developmentGO:0021510810.019
regulation of membrane protein ectodomain proteolysisGO:005104330.019
digestive system developmentGO:00551232000.019
cellular amine metabolic processGO:0044106440.019
pharynx developmentGO:006046510.019
cellular response to transforming growth factor beta stimulusGO:0071560880.019
blastocyst developmentGO:0001824800.019
single organism cell adhesionGO:00986021560.018
purine ribonucleoside metabolic processGO:00461282410.018
maintenance of locationGO:0051235890.018
carbohydrate homeostasisGO:00335001280.018
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433640.018
nucleoside catabolic processGO:00091642060.018
lateral inhibitionGO:004633110.018
organelle assemblyGO:00709251770.018
regulation of multi organism processGO:00439001110.018
glycosyl compound metabolic processGO:19016572460.018
signal transduction in absence of ligandGO:0038034550.018
early endosome to late endosome transportGO:004502220.018
glycosyl compound catabolic processGO:19016582060.018
protein processingGO:00164851630.018
adult behaviorGO:00305341350.017
negative regulation of protein metabolic processGO:00512482820.017
heterocycle catabolic processGO:00467002800.017
stem cell proliferationGO:00720891170.017
tissue remodelingGO:00487711020.017
apoptotic signaling pathwayGO:00971903060.017
membrane lipid metabolic processGO:0006643530.017
positive regulation of transcription by glucoseGO:004601630.017
hormone secretionGO:00468791280.017
t cell activationGO:00421102890.017
negative regulation of cell activationGO:00508661110.017
response to protozoanGO:0001562280.017
stem cell differentiationGO:00488632680.016
nucleoside phosphate catabolic processGO:19012922220.016
reverse cholesterol transportGO:004369160.016
transition metal ion transportGO:0000041380.016
positive regulation of phagocytosisGO:0050766260.016
small molecule biosynthetic processGO:00442831320.016
oocyte constructionGO:000730820.016
intestinal epithelial structure maintenanceGO:006072940.016
organonitrogen compound catabolic processGO:19015652640.016
protein maturationGO:00516041760.016
cellular response to biotic stimulusGO:0071216920.016
positive regulation of cellular amine metabolic processGO:003324050.016
response to lipopolysaccharideGO:00324961280.016
pallium developmentGO:00215431200.016
regulation of protein catabolic processGO:00421761080.016
activation of immune responseGO:00022531380.016
nuclear divisionGO:00002801580.015
immune response regulating cell surface receptor signaling pathwayGO:0002768800.015
dna recombinationGO:0006310920.015
immunoglobulin productionGO:0002377730.015
regulation of cytokine productionGO:00018172660.015
response to molecule of bacterial originGO:00022371430.015
regulation of neurotransmitter levelsGO:0001505870.015
anion transportGO:00068201770.015
nucleoside triphosphate metabolic processGO:00091412300.015
purine containing compound catabolic processGO:00725232130.015
megakaryocyte differentiationGO:0030219260.015
negative regulation of cytokine productionGO:0001818840.015
regulation of defense responseGO:00313472330.015
positive regulation of proteolysisGO:0045862850.015
exocytosisGO:00068871210.014
cellular nitrogen compound catabolic processGO:00442702800.014
t cell differentiationGO:00302171740.014
regulation of leukocyte mediated immunityGO:00027031040.014
regulation of vesicle mediated transportGO:00606271390.014
positive regulation of mapk cascadeGO:00434101700.014
negative regulation of cellular catabolic processGO:0031330470.014
organic anion transportGO:00157111370.014
positive regulation of phagocytosis engulfmentGO:006010030.014
inorganic ion transmembrane transportGO:00986602340.014
peptide transportGO:00158331330.014
organonitrogen compound biosynthetic processGO:19015661920.014
cognitionGO:00508901490.014
ear developmentGO:00435832000.014
response to organonitrogen compoundGO:00102432460.014
forebrain developmentGO:00309003020.014
purine ribonucleotide catabolic processGO:00091542080.014
negative regulation of glycoprotein metabolic processGO:190301930.014
positive regulation of protein catabolic processGO:0045732600.014
development of primary sexual characteristicsGO:00451371430.014
regulation of cysteine type endopeptidase activityGO:2000116650.014
ribonucleoside metabolic processGO:00091192450.013
ameboidal type cell migrationGO:00016671280.013
ossificationGO:00015032160.013
positive regulation of b cell activationGO:0050871490.013
carbohydrate derivative catabolic processGO:19011362310.013
intracellular protein transportGO:00068862040.013
endocytosisGO:00068971680.013
thick ascending limb developmentGO:007202320.013
glucose homeostasisGO:00425931280.013
regulation of cell projection organizationGO:00313442060.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
muscle cell differentiationGO:00426922610.013
neural tube closureGO:0001843900.013
reactive nitrogen species metabolic processGO:200105700.013
regulation of production of molecular mediator of immune responseGO:0002700650.013
peptide secretionGO:00027901140.013
signal transduction involved in mitotic dna damage checkpointGO:190240230.013
regulation of leukocyte differentiationGO:19021051590.013
stem cell maintenanceGO:00198271300.013
negative regulation of intracellular signal transductionGO:19025321670.013
placenta developmentGO:00018901400.013
negative regulation of lymphocyte activationGO:0051250910.013
epithelium migrationGO:0090132630.013
cellular amino acid metabolic processGO:00065201030.013
leukocyte activation involved in immune responseGO:00023661260.013
t cell mediated cytotoxicityGO:0001913260.013
tissue migrationGO:0090130680.013
homotypic cell cell adhesionGO:0034109280.013
dendrite developmentGO:00163581150.013
wnt signaling pathwayGO:00160551880.013
amine metabolic processGO:0009308450.013
anatomical structure homeostasisGO:00602491450.013
exosomal secretionGO:199018210.013
morphogenesis of embryonic epitheliumGO:00163311590.013
forebrain ventricular zone progenitor cell divisionGO:002186960.012
catecholamine metabolic processGO:0006584300.012
natural killer cell mediated cytotoxicityGO:0042267290.012
modification dependent protein catabolic processGO:00199411330.012
protein targeting to lysosomeGO:000662220.012
alcohol metabolic processGO:00060661160.012
gonad developmentGO:00084061410.012
response to peptideGO:19016521360.012
negative regulation of cell developmentGO:00107211690.012
peptide hormone secretionGO:00300721090.012
response to superoxideGO:0000303160.012
hematopoietic progenitor cell differentiationGO:00022441430.012
head morphogenesisGO:0060323340.012
midgut developmentGO:000749440.012
neurotransmitter secretionGO:0007269620.012
neuromuscular process controlling balanceGO:0050885590.012
carbohydrate derivative biosynthetic processGO:19011371830.012
regulation of anion transportGO:0044070270.012
equilibrioceptionGO:005095730.012
single fertilizationGO:0007338820.012
sphingolipid metabolic processGO:0006665450.012
somatic stem cell divisionGO:0048103190.012
response to oxidative stressGO:00069791230.012
actomyosin structure organizationGO:0031032560.012
positive regulation of protein modification processGO:00314012990.012
regulation of exocytosisGO:0017157610.012
calcium ion dependent exocytosisGO:0017156350.012
single organismal cell cell adhesionGO:00163371310.012
regulation of excitatory postsynaptic membrane potentialGO:0060079410.012
oocyte anterior posterior axis specificationGO:000731420.012
cellular response to abiotic stimulusGO:0071214560.012
forebrain generation of neuronsGO:0021872630.012
protein localization to membraneGO:00726571080.012
cell divisionGO:00513011200.012
mesenchymal cell developmentGO:0014031930.012
positive regulation of cytokine productionGO:00018191740.011
regulation of leukocyte apoptotic processGO:2000106560.011
sterol transportGO:0015918380.011
transforming growth factor beta receptor signaling pathwayGO:0007179710.011
cellular response to lipidGO:00713961450.011
neuron apoptotic processGO:00514021420.011
regulation of proteolysisGO:00301621640.011
regulation of cellular amino acid metabolic processGO:000652150.011
defense response to gram negative bacteriumGO:0050829280.011
regulation of actin filament based processGO:0032970990.011
protein ubiquitinationGO:00165671710.011
regulation of hormone levelsGO:00108172110.011
positive regulation of cytokine secretionGO:0050715410.011
regulation of peptide hormone secretionGO:0090276750.011
regulation of gamma aminobutyric acid secretionGO:001405220.011
morphogenesis of a branching structureGO:00017632030.011
response to temperature stimulusGO:0009266550.011
calcium ion transportGO:00068161590.011
regulation of cellular protein catabolic processGO:1903362610.011
response to acid chemicalGO:00011011110.011
regulation of bone resorptionGO:0045124240.011
ribonucleotide catabolic processGO:00092612080.011
antigen processing and presentationGO:0019882470.011
chemotaxisGO:00069352470.011
forebrain neuroblast divisionGO:002187390.011
regulation of embryonic developmentGO:0045995710.011
leukocyte chemotaxisGO:0030595690.011
phagolysosome assemblyGO:000184530.011
regulation of establishment of protein localizationGO:00702011810.011
interleukin 13 secretionGO:007261120.011
ribose phosphate metabolic processGO:00196932910.011
cellular response to growth factor stimulusGO:00713631970.011
positive regulation of gamma aminobutyric acid secretionGO:001405420.011
negative regulation of hydrolase activityGO:0051346710.010
organophosphate biosynthetic processGO:00904071220.010
negative regulation of synaptic vesicle transportGO:190280430.010
purine ribonucleoside triphosphate metabolic processGO:00092052200.010
regulation of protein transportGO:00512231630.010
aromatic amino acid family metabolic processGO:000907290.010
positive regulation of immune effector processGO:00026991070.010
cilium morphogenesisGO:00602711020.010
neural precursor cell proliferationGO:00613511210.010
glutamate receptor signaling pathwayGO:0007215350.010
negative regulation of cellular component organizationGO:00511291940.010
innate immune response in mucosaGO:000222730.010
lymphocyte activation involved in immune responseGO:0002285930.010
regulation of alpha beta t cell differentiationGO:0046637350.010
tyrosine metabolic processGO:000657040.010

Hps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
nervous system diseaseDOID:86300.065
inherited metabolic disorderDOID:65500.040
disease of metabolismDOID:001466700.040
sensory system diseaseDOID:005015500.028
eye diseaseDOID:561400.028
eye and adnexa diseaseDOID:149200.028
immune system diseaseDOID:291400.021
retinal diseaseDOID:567900.019
central nervous system diseaseDOID:33100.016
neurodegenerative diseaseDOID:128900.016
retinal degenerationDOID:846600.016
connective tissue diseaseDOID:6500.016
musculoskeletal system diseaseDOID:1700.016
bone diseaseDOID:008000100.011