Mus musculus

0 known processes

Sppl3

signal peptide peptidase 3

(Aliases: Usmg3,4833416I09Rik,MGC90867,Psl4)

Sppl3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular ketone metabolic processGO:0010565660.158
regulation of cellular amine metabolic processGO:0033238200.099
purine containing compound metabolic processGO:00725213110.086
proteolysis involved in cellular protein catabolic processGO:00516031470.072
amine metabolic processGO:0009308450.065
male gamete generationGO:00482322850.064
regulation of membrane potentialGO:00423911920.062
macromolecule catabolic processGO:00090572810.058
cellular macromolecule catabolic processGO:00442652060.056
cellular amine metabolic processGO:0044106440.055
cellular ketone metabolic processGO:0042180840.053
purine nucleotide metabolic processGO:00061633020.052
spermatogenesisGO:00072832840.050
apoptotic signaling pathwayGO:00971903060.050
mitotic cell cycle processGO:19030471590.049
cellular amino acid metabolic processGO:00065201030.048
heterocycle catabolic processGO:00467002800.047
rhythmic processGO:00485111740.047
cell growthGO:00160491300.045
regulation of cellular catabolic processGO:00313292420.044
negative regulation of cellular component organizationGO:00511291940.044
myeloid cell differentiationGO:00300992330.043
regulation of neuron differentiationGO:00456642810.043
cellular nitrogen compound catabolic processGO:00442702800.042
regulation of cellular amino acid metabolic processGO:000652150.041
cytoplasmic transportGO:00164822340.041
skeletal system developmentGO:00015013560.041
protein modification by small protein conjugation or removalGO:00706472070.041
asymmetric stem cell divisionGO:009872230.040
negative regulation of protein metabolic processGO:00512482820.040
regulation of cell cycleGO:00517262810.040
microtubule cytoskeleton organizationGO:00002261570.040
response to organonitrogen compoundGO:00102432460.039
purine containing compound catabolic processGO:00725232130.039
muscle cell differentiationGO:00426922610.039
organic cyclic compound catabolic processGO:19013612950.039
negative regulation of organelle organizationGO:0010639900.038
negative regulation of molecular functionGO:00440922580.037
ubiquitin dependent protein catabolic processGO:00065111290.037
regulation of cellular component biogenesisGO:00440871810.036
rho protein signal transductionGO:0007266320.036
asymmetric neuroblast divisionGO:005505910.036
negative regulation of protein modification processGO:00314001630.036
negative regulation of cellular amine metabolic processGO:003323910.036
germ cell developmentGO:00072811850.036
purine ribonucleoside triphosphate catabolic processGO:00092071990.036
nucleoside phosphate metabolic processGO:00067533380.035
ras protein signal transductionGO:0007265770.035
regulation of cell projection organizationGO:00313442060.035
establishment of organelle localizationGO:00516561220.034
axonogenesisGO:00074092740.034
muscle tissue developmentGO:00605373080.034
homeostasis of number of cellsGO:00488722100.034
ribonucleoside catabolic processGO:00424542060.034
regulation of neuron projection developmentGO:00109751690.033
maintenance of locationGO:0051235890.032
aromatic compound catabolic processGO:00194392860.032
cellular response to dna damage stimulusGO:00069742070.032
modification dependent macromolecule catabolic processGO:00436321330.031
mitotic cell cycleGO:00002781950.031
regulation of lymphocyte activationGO:00512492400.031
striated muscle tissue developmentGO:00147062930.031
protein polyubiquitinationGO:0000209330.031
positive regulation of nervous system developmentGO:00519622210.031
retrograde transport endosome to golgiGO:004214720.031
intracellular protein transportGO:00068862040.030
microtubule based processGO:00070172360.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
lymphocyte homeostasisGO:0002260640.030
negative regulation of cellular amino acid metabolic processGO:004576300.029
positive regulation of cell developmentGO:00107202370.029
nucleoside catabolic processGO:00091642060.029
glycosyl compound metabolic processGO:19016572460.029
regulation of apoptotic signaling pathwayGO:20012331970.029
cell adhesionGO:00071553290.029
purine nucleoside catabolic processGO:00061522050.029
negative regulation of cell cycleGO:00457861230.029
cognitionGO:00508901490.028
chemotaxisGO:00069352470.028
regulation of cell morphogenesis involved in differentiationGO:00107691510.028
protein ubiquitinationGO:00165671710.028
blood circulationGO:00080151950.028
regulation of secretionGO:00510462740.028
regionalizationGO:00030023370.028
regulation of synaptic growth at neuromuscular junctionGO:000858240.027
ribonucleoside metabolic processGO:00091192450.027
ribose phosphate metabolic processGO:00196932910.027
organelle assemblyGO:00709251770.027
regulation of cell activationGO:00508652890.027
negative regulation of cell proliferationGO:00082852960.027
purine nucleoside triphosphate metabolic processGO:00091442260.027
purine ribonucleotide metabolic processGO:00091502900.027
wnt signaling pathwayGO:00160551880.027
ossificationGO:00015032160.026
actin cytoskeleton organizationGO:00300362200.026
nucleoside triphosphate catabolic processGO:00091432050.026
learning or memoryGO:00076111480.026
negative regulation of nervous system developmentGO:00519611560.026
nuclear transportGO:00511691390.025
cellular protein catabolic processGO:00442571550.025
regulation of organelle organizationGO:00330432890.025
lateral inhibitionGO:004633110.025
small gtpase mediated signal transductionGO:0007264970.025
regulation of sequence specific dna binding transcription factor activityGO:00510901060.025
multicellular organismal signalingGO:0035637910.025
purine ribonucleoside triphosphate metabolic processGO:00092052200.025
positive regulation of cellular catabolic processGO:00313311480.025
mitochondrion organizationGO:00070051340.025
regulation of hydrolase activityGO:00513362460.024
ribonucleotide metabolic processGO:00092592910.024
developmental maturationGO:00217001930.024
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.024
nucleobase containing small molecule metabolic processGO:00550863520.024
leukocyte homeostasisGO:0001776790.024
positive regulation of cell deathGO:00109422240.024
neural tube developmentGO:00219151600.024
guanosine containing compound catabolic processGO:19010691440.024
synaptic transmissionGO:00072683290.024
regulation of protein localizationGO:00328802310.024
negative regulation of cellular protein metabolic processGO:00322692470.023
heart morphogenesisGO:00030071780.023
regulation of purine nucleotide metabolic processGO:19005421690.023
regulation of anatomical structure sizeGO:00900661780.023
regulation of intracellular transportGO:00323861590.023
locomotory behaviorGO:00076261950.023
purine nucleoside metabolic processGO:00422782410.022
cellular response to hormone stimulusGO:00328701500.022
modification dependent protein catabolic processGO:00199411330.022
cytokine productionGO:00018163190.022
regulation of cell growthGO:0001558910.022
skin developmentGO:00435882200.022
histone modificationGO:00165701590.022
carbohydrate derivative catabolic processGO:19011362310.022
protein maturationGO:00516041760.022
organonitrogen compound biosynthetic processGO:19015661920.022
negative regulation of synapse assemblyGO:005196430.022
cellular protein complex assemblyGO:00436231160.022
nucleotide metabolic processGO:00091173320.021
regulation of t cell activationGO:00508631700.021
dephosphorylationGO:00163111290.021
circadian rhythmGO:00076231140.021
meiotic cell cycle processGO:1903046770.021
regulation of bindingGO:00510981110.021
histone lysine methylationGO:0034968500.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.021
organelle localizationGO:00516401790.021
nuclear divisionGO:00002801580.021
purine nucleotide catabolic processGO:00061952110.021
regulation of cellular response to stressGO:00801351590.021
regulation of leukocyte differentiationGO:19021051590.021
ribonucleoside triphosphate metabolic processGO:00091992200.021
protein catabolic processGO:00301632210.021
regulation of transferase activityGO:00513382630.020
cell fate commitmentGO:00451652100.020
circulatory system processGO:00030131970.020
regulation of nucleotide catabolic processGO:00308111220.020
regulation of mitotic cell cycle phase transitionGO:1901990730.020
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.020
blood vessel morphogenesisGO:00485142850.020
protein modification by small protein conjugationGO:00324461870.020
limb morphogenesisGO:00351081490.020
regulation of actin filament polymerizationGO:0030833380.020
positive regulation of bindingGO:0051099490.020
proteasomal protein catabolic processGO:0010498980.020
organophosphate catabolic processGO:00464342320.020
protein localization to organelleGO:00333651850.020
positive regulation of cellular amine metabolic processGO:003324050.019
respiratory tube developmentGO:00303231670.019
positive regulation of dna templated transcription elongationGO:003278620.019
compound eye developmentGO:004874910.019
carbohydrate metabolic processGO:00059752300.019
developmental growth involved in morphogenesisGO:00605601380.019
negative regulation of growthGO:0045926990.019
positive regulation of protein modification processGO:00314012990.019
organelle fissionGO:00482851700.019
t cell activationGO:00421102890.019
regulation of protein transportGO:00512231630.019
meiotic cell cycleGO:00513211220.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
lipid localizationGO:00108761260.019
regulation of secretion by cellGO:19035302490.019
carbohydrate derivative biosynthetic processGO:19011371830.019
actin filament polymerizationGO:0030041440.019
nucleotide catabolic processGO:00091662170.019
nucleoside phosphate catabolic processGO:19012922220.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019
gland developmentGO:00487323300.019
membrane organizationGO:00610242450.019
regulation of establishment of protein localizationGO:00702011810.018
embryonic limb morphogenesisGO:00303261260.018
negative regulation of protein phosphorylationGO:00019331260.018
intrinsic apoptotic signaling pathwayGO:00971931320.018
regulation of cytokine productionGO:00018172660.018
response to growth factorGO:00708481980.018
forebrain developmentGO:00309003020.018
erythrocyte differentiationGO:0030218880.018
epithelial tube morphogenesisGO:00605623030.018
muscle cell developmentGO:00550011330.018
ribonucleoside triphosphate catabolic processGO:00092031990.018
memoryGO:0007613580.018
cell type specific apoptotic processGO:00972852680.018
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.018
inflammatory responseGO:00069542440.018
immune effector processGO:00022523210.018
single organism cell adhesionGO:00986021560.017
protein processingGO:00164851630.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.017
carbohydrate homeostasisGO:00335001280.017
epithelial cell proliferationGO:00506731740.017
innate immune responseGO:00450871570.017
cellular component assembly involved in morphogenesisGO:00109271390.017
ribonucleotide catabolic processGO:00092612080.017
peptidyl amino acid modificationGO:00181933360.017
endocytosisGO:00068971680.017
cation transmembrane transportGO:00986552660.017
negative regulation of phosphate metabolic processGO:00459361840.017
digestive system developmentGO:00551232000.017
cellular homeostasisGO:00197252400.017
cellular response to cytokine stimulusGO:00713451890.017
actin filament organizationGO:00070151130.017
extrinsic apoptotic signaling pathwayGO:00971911260.017
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.017
nucleocytoplasmic transportGO:00069131390.017
action potentialGO:0001508780.017
covalent chromatin modificationGO:00165691630.017
regulation of mapk cascadeGO:00434082480.017
purine ribonucleotide catabolic processGO:00091542080.017
transmission of nerve impulseGO:0019226760.017
positive regulation of programmed cell deathGO:00430682180.017
regulation of hormone levelsGO:00108172110.017
cellular carbohydrate metabolic processGO:00442621190.016
response to molecule of bacterial originGO:00022371430.016
positive regulation of apoptotic processGO:00430652170.016
endomembrane system organizationGO:00102561470.016
regulation of nucleoside metabolic processGO:00091181300.016
respiratory system developmentGO:00605411900.016
glycosyl compound catabolic processGO:19016582060.016
developmental cell growthGO:0048588840.016
posttranscriptional regulation of gene expressionGO:00106081550.016
cytokine mediated signaling pathwayGO:00192211150.016
regulation of circadian rhythmGO:0042752580.016
oocyte constructionGO:000730820.016
regulation of protein bindingGO:0043393600.016
negative regulation of phosphorus metabolic processGO:00105631840.016
ion transmembrane transportGO:00342203610.016
regulation of cell motilityGO:20001452360.016
regulation of chromosome organizationGO:0033044830.016
myotube differentiationGO:00149021050.016
regulation of ossificationGO:00302781120.016
cellular lipid metabolic processGO:00442553230.015
cellularizationGO:000734910.015
regulation of system processGO:00440572000.015
negative regulation of cell developmentGO:00107211690.015
positive regulation of apoptotic signaling pathwayGO:2001235950.015
nucleoside metabolic processGO:00091162460.015
regulation of purine nucleotide catabolic processGO:00331211220.015
transmembrane transportGO:00550854120.015
multicellular organism growthGO:00352641610.015
protein deacylationGO:0035601360.015
meiosis iGO:0007127600.015
positive regulation of purine nucleotide catabolic processGO:0033123880.015
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.015
regulation of gtp catabolic processGO:00331241130.015
regulation of cellular protein catabolic processGO:1903362610.015
actin polymerization or depolymerizationGO:0008154540.015
female gamete generationGO:0007292740.015
leukocyte differentiationGO:00025213420.015
oocyte axis specificationGO:000730920.015
positive regulation of hydrolase activityGO:00513451480.015
response to peptideGO:19016521360.015
protein importGO:00170381010.015
digestive tract morphogenesisGO:00485461470.015
response to light stimulusGO:00094161350.015
dna repairGO:00062811070.015
nucleoside triphosphate metabolic processGO:00091412300.014
canonical wnt signaling pathwayGO:00600701300.014
epithelial tube formationGO:00721751300.014
regulation of extent of cell growthGO:0061387520.014
response to insulinGO:00328681000.014
positive regulation of cell activationGO:00508671580.014
lymphocyte proliferationGO:00466511640.014
protein secretionGO:00093061110.014
negative regulation of glial cell proliferationGO:006025340.014
cellular response to growth factor stimulusGO:00713631970.014
kidney developmentGO:00018222130.014
nitrogen compound transportGO:00717052710.014
purine ribonucleoside metabolic processGO:00461282410.014
regulation of myeloid cell differentiationGO:0045637960.014
regulation of protein processingGO:0070613960.014
regulation of adaptive immune responseGO:0002819900.014
dna metabolic processGO:00062593030.014
b cell activationGO:00421131610.014
protein localization to membraneGO:00726571080.014
mapk cascadeGO:00001652810.014
sensory organ morphogenesisGO:00905962420.014
regulation of cellular component sizeGO:00325351210.014
dendrite developmentGO:00163581150.014
organophosphate biosynthetic processGO:00904071220.014
exocytosisGO:00068871210.014
regulation of lymphocyte proliferationGO:00506701170.014
establishment of protein localization to organelleGO:00725941180.014
myeloid cell homeostasisGO:00022621140.014
cardiac muscle tissue developmentGO:00487381300.014
gtp metabolic processGO:00460391440.014
sulfur compound biosynthetic processGO:0044272370.014
maternal determination of anterior posterior axis embryoGO:000835820.014
cellular response to lipidGO:00713961450.014
regulation of defense responseGO:00313472330.014
hormone secretionGO:00468791280.013
oogenesisGO:0048477560.013
limb developmentGO:00601731660.013
regulation of homeostatic processGO:00328441820.013
connective tissue developmentGO:00614481790.013
appendage developmentGO:00487361660.013
adult behaviorGO:00305341350.013
cell divisionGO:00513011200.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.013
establishment or maintenance of cytoskeleton polarityGO:003095220.013
negative regulation of immune system processGO:00026832090.013
protein acylationGO:0043543640.013
neuron deathGO:00709971540.013
organic hydroxy compound transportGO:0015850930.013
regulation of histone modificationGO:0031056560.013
stem cell differentiationGO:00488632680.013
response to radiationGO:00093141650.013
renal system developmentGO:00720012250.013
cartilage developmentGO:00512161400.013
chromatin organizationGO:00063252060.013
skeletal system morphogenesisGO:00487052030.013
sensory perceptionGO:00076002450.013
regulation of lymphocyte differentiationGO:00456191070.013
fertilizationGO:00095661270.013
regulation of protein catabolic processGO:00421761080.013
lymphocyte mediated immunityGO:00024491390.013
protein localization to nucleusGO:00345041210.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.013
macromolecule methylationGO:00434141200.013
skeletal muscle organ developmentGO:00605381630.013
meiotic nuclear divisionGO:00071261150.013
negative regulation of phosphorylationGO:00423261660.013
tube formationGO:00351481400.013
lipid transportGO:0006869980.013
single fertilizationGO:0007338820.013
regulation of actin polymerization or depolymerizationGO:0008064450.013
oocyte anterior posterior axis specificationGO:000731420.013
positive regulation of t cell activationGO:00508701010.013
regulation of mitotic cell cycleGO:00073461260.013
cellular response to peptideGO:1901653920.013
protein targetingGO:00066051430.013
regulation of proteolysisGO:00301621640.013
regulation of inflammatory responseGO:00507271470.013
positive regulation of nucleoside metabolic processGO:0045979910.012
reactive oxygen species biosynthetic processGO:190340980.012
positive regulation of leukocyte differentiationGO:1902107860.012
positive regulation of neuron projection developmentGO:0010976790.012
negative regulation of neuron differentiationGO:00456651010.012
positive regulation of secretionGO:00510471300.012
spermatid developmentGO:00072861080.012
cellular response to organonitrogen compoundGO:00714171450.012
negative regulation of mapk cascadeGO:0043409650.012
dna alkylationGO:0006305430.012
determination of left right symmetryGO:0007368800.012
leukocyte mediated immunityGO:00024431740.012
immune response regulating signaling pathwayGO:00027641250.012
regulation of leukocyte proliferationGO:00706631210.012
positive regulation of nucleotide metabolic processGO:00459811140.012
guanosine containing compound metabolic processGO:19010681440.012
regulation of schwann cell proliferationGO:001062420.012
protein methylationGO:0006479810.012
purine ribonucleoside catabolic processGO:00461302050.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.012
protein polymerizationGO:0051258570.012
response to lipopolysaccharideGO:00324961280.012
heart contractionGO:0060047930.012
regulation of cell cycle processGO:00105641600.012
angiogenesisGO:00015252010.012
regulation of chromatin organizationGO:1902275570.012
glucose homeostasisGO:00425931280.012
negative regulation of intracellular signal transductionGO:19025321670.012
positive regulation of protein kinase activityGO:00458601440.012
positive regulation of lymphocyte activationGO:00512511400.012
adaptive immune responseGO:00022501550.012
rna processingGO:00063961050.012
bmp signaling pathwayGO:0030509930.012
positive regulation of cell projection organizationGO:0031346950.012
lung developmentGO:00303241640.012
negative regulation of cytoskeleton organizationGO:0051494360.012
learningGO:0007612980.012
protein import into nucleusGO:0006606950.011
regulation of kinase activityGO:00435492490.011
regulation of response to dna damage stimulusGO:2001020340.011
methylationGO:00322591340.011
neuron projection extensionGO:1990138640.011
negative regulation of lymphocyte activationGO:0051250910.011
stem cell maintenanceGO:00198271300.011
regulation of cell migrationGO:00303342190.011
retina development in camera type eyeGO:00600411190.011
divalent inorganic cation homeostasisGO:00725071380.011
myeloid leukocyte differentiationGO:00025731190.011
primary neural tube formationGO:0014020950.011
regulation of map kinase activityGO:00434051200.011
palate developmentGO:0060021760.011
regulation of chromatin modificationGO:1903308570.011
positive regulation of defense responseGO:00313491240.011
photoreceptor cell morphogenesisGO:000859430.011
axon ensheathmentGO:0008366760.011
positive regulation of cell cycleGO:0045787920.011
actin filament based movementGO:0030048230.011
development of primary sexual characteristicsGO:00451371430.011
regulation of blood circulationGO:1903522930.011
chromatin modificationGO:00165681870.011
lipid biosynthetic processGO:00086101790.011
striated muscle cell developmentGO:00550021250.011
appendage morphogenesisGO:00351071490.011
response to organic cyclic compoundGO:00140701980.011
telencephalon developmentGO:00215371860.011
signal transduction in absence of ligandGO:0038034550.011
protein deacetylationGO:0006476320.011
positive regulation of immune effector processGO:00026991070.011
regulation of gliogenesisGO:0014013500.011
neural precursor cell proliferationGO:00613511210.011
organic hydroxy compound metabolic processGO:19016152030.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
regulation of cell cycle phase transitionGO:1901987770.011
mitochondrion distributionGO:004831140.011
tissue homeostasisGO:00018941150.011
gonad developmentGO:00084061410.011
cell maturationGO:00484691270.011
embryonic skeletal system developmentGO:00487061200.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
tube closureGO:0060606910.011
smoothened signaling pathwayGO:00072241050.010
synapse organizationGO:00508081250.010
attachment of spindle microtubules to kinetochoreGO:000860840.010
glial cell differentiationGO:00100011310.010
regulation of response to woundingGO:19030341890.010
i kappab kinase nf kappab signalingGO:0007249850.010
negative regulation of mitotic cell cycleGO:0045930580.010
gtp catabolic processGO:00061841430.010
myelinationGO:0042552740.010
negative regulation of kinase activityGO:0033673810.010
dna modificationGO:0006304500.010
neural tube closureGO:0001843900.010
cell cycle g1 s phase transitionGO:0044843570.010
sequestering of calcium ionGO:0051208180.010
divalent metal ion transportGO:00708381720.010
hematopoietic progenitor cell differentiationGO:00022441430.010
cardiac chamber morphogenesisGO:0003206930.010
negative regulation of cell projection organizationGO:0031345560.010
reactive nitrogen species metabolic processGO:200105700.010
macromolecule deacylationGO:0098732370.010
regulation of cell adhesionGO:00301551540.010

Sppl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.025
cardiovascular system diseaseDOID:128700.022
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.017
organ system cancerDOID:005068600.015
connective tissue diseaseDOID:6500.011
musculoskeletal system diseaseDOID:1700.011
central nervous system diseaseDOID:33100.011