| covalent chromatin modification | GO:0016569 | 163 | 0.741 | Human |
| histone methylation | GO:0016571 | 71 | 0.441 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.436 | Human |
| chromatin silencing | GO:0006342 | 15 | 0.322 | |
| dna metabolic process | GO:0006259 | 303 | 0.297 | |
| histone modification | GO:0016570 | 159 | 0.265 | Human |
| macromolecule methylation | GO:0043414 | 120 | 0.209 | |
| methylation | GO:0032259 | 134 | 0.205 | |
| histone lysine methylation | GO:0034968 | 50 | 0.190 | |
| protein alkylation | GO:0008213 | 81 | 0.162 | |
| protein methylation | GO:0006479 | 81 | 0.137 | |
| gene silencing | GO:0016458 | 38 | 0.113 | |
| negative regulation of chromatin silencing | GO:0031936 | 1 | 0.110 | |
| histone h3 k4 trimethylation | GO:0080182 | 5 | 0.110 | |
| mrna metabolic process | GO:0016071 | 84 | 0.106 | |
| multicellular organism growth | GO:0035264 | 161 | 0.099 | |
| peptidyl lysine methylation | GO:0018022 | 29 | 0.097 | |
| chromatin organization | GO:0006325 | 206 | 0.093 | Human |
| stem cell fate specification | GO:0048866 | 3 | 0.085 | |
| chromatin modification | GO:0016568 | 187 | 0.080 | Human |
| histone h3 k9 methylation | GO:0051567 | 17 | 0.080 | |
| regulation of chromatin silencing | GO:0031935 | 2 | 0.078 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.076 | |
| histone h3 k4 methylation | GO:0051568 | 23 | 0.076 | |
| rna processing | GO:0006396 | 105 | 0.069 | |
| dna methylation | GO:0006306 | 43 | 0.068 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 28 | 0.068 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.062 | |
| intracellular receptor signaling pathway | GO:0030522 | 74 | 0.062 | |
| dna recombination | GO:0006310 | 92 | 0.061 | |
| spermatogenesis | GO:0007283 | 284 | 0.058 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.055 | |
| digestive system development | GO:0055123 | 200 | 0.054 | Human |
| epithelial cell development | GO:0002064 | 159 | 0.054 | |
| male gamete generation | GO:0048232 | 285 | 0.050 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.049 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.047 | Human |
| histone h3 k9 trimethylation | GO:0036124 | 6 | 0.046 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.046 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.046 | |
| regulation of gene silencing | GO:0060968 | 7 | 0.045 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.044 | |
| dna repair | GO:0006281 | 107 | 0.043 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.042 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.042 | Human |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.041 | |
| cellular response to lipid | GO:0071396 | 145 | 0.040 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.039 | |
| stem cell maintenance | GO:0019827 | 130 | 0.038 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.036 | |
| protein acylation | GO:0043543 | 64 | 0.036 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.036 | |
| positive regulation of histone h3 k9 methylation | GO:0051574 | 4 | 0.036 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.036 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.035 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.035 | |
| blastocyst development | GO:0001824 | 80 | 0.035 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.033 | |
| digestive tract development | GO:0048565 | 190 | 0.033 | Human |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.033 | |
| actin mediated cell contraction | GO:0070252 | 15 | 0.033 | |
| nucleosome positioning | GO:0016584 | 4 | 0.032 | |
| immune effector process | GO:0002252 | 321 | 0.032 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.032 | |
| regulation of protein stability | GO:0031647 | 52 | 0.031 | |
| neural tube development | GO:0021915 | 160 | 0.031 | |
| mapk cascade | GO:0000165 | 281 | 0.031 | |
| regulation of system process | GO:0044057 | 200 | 0.030 | |
| regulation of histone modification | GO:0031056 | 56 | 0.030 | Human |
| cytoplasmic mrna processing body assembly | GO:0033962 | 6 | 0.029 | |
| regulation of histone h3 k9 methylation | GO:0051570 | 8 | 0.028 | |
| protein dna complex subunit organization | GO:0071824 | 28 | 0.028 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.028 | |
| multi organism reproductive behavior | GO:0044705 | 29 | 0.028 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.027 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 15 | 0.026 | |
| regulation of jak stat cascade | GO:0046425 | 34 | 0.026 | |
| compound eye development | GO:0048749 | 1 | 0.025 | |
| epithalamus development | GO:0021538 | 2 | 0.024 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.024 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.023 | |
| regulation of rna export from nucleus | GO:0046831 | 4 | 0.023 | |
| nuclear transcribed mrna catabolic process | GO:0000956 | 16 | 0.022 | |
| negative regulation of mesenchymal cell proliferation | GO:0072201 | 3 | 0.022 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.022 | |
| rna catabolic process | GO:0006401 | 29 | 0.022 | |
| regulation of cell motility | GO:2000145 | 236 | 0.021 | |
| stem cell development | GO:0048864 | 219 | 0.021 | |
| respiratory system development | GO:0060541 | 190 | 0.021 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 49 | 0.021 | |
| amine metabolic process | GO:0009308 | 45 | 0.020 | |
| gonad development | GO:0008406 | 141 | 0.020 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.020 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.020 | |
| lung development | GO:0030324 | 164 | 0.020 | |
| regulation of cell migration | GO:0030334 | 219 | 0.020 | |
| dna damage checkpoint | GO:0000077 | 26 | 0.020 | |
| central nervous system projection neuron axonogenesis | GO:0021952 | 21 | 0.019 | |
| male sex differentiation | GO:0046661 | 109 | 0.019 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.019 | |
| central nervous system neuron differentiation | GO:0021953 | 162 | 0.019 | |
| negative regulation of vasculature development | GO:1901343 | 26 | 0.019 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.019 | |
| endocytosis | GO:0006897 | 168 | 0.019 | |
| multicellular organismal reproductive behavior | GO:0033057 | 23 | 0.019 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.019 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.018 | Human |
| regulation of gene expression by genetic imprinting | GO:0006349 | 15 | 0.018 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.018 | |
| rna interference | GO:0016246 | 2 | 0.018 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 29 | 0.018 | |
| male gonad development | GO:0008584 | 88 | 0.018 | |
| regulation of defense response | GO:0031347 | 233 | 0.018 | |
| gene silencing by mirna | GO:0035195 | 10 | 0.018 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.018 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.017 | |
| negative regulation of bmp signaling pathway | GO:0030514 | 35 | 0.017 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.017 | |
| negative regulation of gene silencing | GO:0060969 | 2 | 0.017 | |
| regulation of rna splicing | GO:0043484 | 37 | 0.017 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.017 | Human |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.017 | |
| habenula development | GO:0021986 | 2 | 0.017 | |
| chromatin silencing at rdna | GO:0000183 | 3 | 0.017 | |
| rna phosphodiester bond hydrolysis | GO:0090501 | 19 | 0.017 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.017 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.016 | |
| t cell activation | GO:0042110 | 289 | 0.016 | |
| heart morphogenesis | GO:0003007 | 178 | 0.016 | Human |
| rab protein signal transduction | GO:0032482 | 1 | 0.016 | |
| oogenesis | GO:0048477 | 56 | 0.016 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.016 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.016 | |
| chromosome organization involved in meiosis | GO:0070192 | 39 | 0.016 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.016 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.016 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.015 | |
| posttranscriptional gene silencing | GO:0016441 | 10 | 0.015 | |
| germ cell development | GO:0007281 | 185 | 0.015 | |
| organelle assembly | GO:0070925 | 177 | 0.015 | |
| cerebellar purkinje cell layer morphogenesis | GO:0021692 | 14 | 0.015 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.015 | |
| multi organism behavior | GO:0051705 | 62 | 0.015 | |
| regulation of chromatin organization | GO:1902275 | 57 | 0.015 | Human |
| protein dealkylation | GO:0008214 | 13 | 0.015 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.014 | |
| histone h3 k9 dimethylation | GO:0036123 | 4 | 0.014 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.014 | |
| histone h3 k36 demethylation | GO:0070544 | 2 | 0.014 | |
| mitotic sister chromatid cohesion | GO:0007064 | 1 | 0.014 | Human |
| histone h4 k20 methylation | GO:0034770 | 8 | 0.014 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.014 | |
| chromatin mediated maintenance of transcription | GO:0048096 | 2 | 0.013 | |
| dna modification | GO:0006304 | 50 | 0.013 | |
| limb development | GO:0060173 | 166 | 0.013 | Human |
| dna alkylation | GO:0006305 | 43 | 0.013 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.013 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.013 | |
| cell division | GO:0051301 | 120 | 0.013 | |
| indole containing compound metabolic process | GO:0042430 | 12 | 0.012 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.012 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.012 | |
| adaptive immune response | GO:0002250 | 155 | 0.012 | |
| neuron projection guidance | GO:0097485 | 141 | 0.012 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.012 | |
| mrna catabolic process | GO:0006402 | 22 | 0.012 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.012 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.012 | |
| mrna processing | GO:0006397 | 63 | 0.012 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.012 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.012 | |
| dendrite development | GO:0016358 | 115 | 0.011 | |
| regulation of platelet derived growth factor receptor alpha signaling pathway | GO:2000583 | 2 | 0.011 | |
| myeloid leukocyte mediated immunity | GO:0002444 | 42 | 0.011 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.011 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.011 | |
| negative regulation of germinal center formation | GO:0002635 | 2 | 0.011 | |
| gene silencing by rna | GO:0031047 | 19 | 0.011 | |
| regulation of innate immune response | GO:0045088 | 91 | 0.011 | |
| multinuclear osteoclast differentiation | GO:0072674 | 4 | 0.011 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.011 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 57 | 0.011 | |
| negative regulation of pancreatic juice secretion | GO:0090188 | 3 | 0.011 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.011 | |
| body morphogenesis | GO:0010171 | 45 | 0.011 | Human |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.011 | |
| regulation of mrna processing | GO:0050684 | 41 | 0.010 | |
| somitogenesis | GO:0001756 | 69 | 0.010 | |
| feeding behavior | GO:0007631 | 62 | 0.010 | |
| chromatin assembly | GO:0031497 | 13 | 0.010 | |
| regulation of viral transcription | GO:0046782 | 3 | 0.010 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.010 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 22 | 0.010 | |
| axon guidance | GO:0007411 | 141 | 0.010 | |
| morphogenesis of an endothelium | GO:0003159 | 2 | 0.010 | |
| regulation of transcription by chromatin organization | GO:0034401 | 0 | 0.010 | |
| epithelial cell morphogenesis | GO:0003382 | 41 | 0.010 | |
| somite development | GO:0061053 | 81 | 0.010 | |
